ClassID:

109136

C12N2310/121 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Type of nucleic acid catalytic nucleic acids, e.g. ribozymes Hammerhead

Recent Application in this class:
#1
20260115275
2026-04-30

RIBOZYME-ACTIVATED RNA CONSTRUCTS AND USES THEREOF

#2
20250369036
2025-12-04

RIBOZYMES

#3
20250304975
2025-10-02

APTAMER AND RIBOZYME EQUILIBRIUM SHIFTING (ARES) RNA CIRCUITS AND USES THEREOF

#4
20250283077
2025-09-11

ENHANCED HAMMERHEAD RIBOZYMES AND METHODS OF USE

#5
20250236889
2025-07-24

METHODS AND COMPOSITIONS FOR TRANSDUCING LYMPHOCYTES AND REGULATING THE ACTIVITY THEREOF

#6
20250230452
2025-07-17

POLYNUCLEOTIDES FOR MODIFYING ORGANISMS

#7
20250215437
2025-07-03

COMPOSITIONS AND METHODS FOR TREATMENT OF DOMINANT RETINITIS PIGMENTOSA

#8
20250179494
2025-06-05

RIBOZYME-ENHANCED RNA TRANS-SPLICING

#9
20250136994
2025-05-01

COMPOSITIONS AND METHODS TO RESTORE PATERNAL UBE3A GENE EXPRESSION IN HUMAN ANGELMAN SYNDROME

#10
20250127932
2025-04-24

METHOD FOR DELIVERING RNA TO NEURONS TO TREAT HERPES INFECTIONS

#11
20250011767
2025-01-09

COMPOSITIONS AND METHODS FOR PRODUCTION OF CIRCULAR NUCLEIC ACID MOLECULES

#12
20240425855
2024-12-26

NUCLEIC ACID-CONTROLLED CATALYTIC RNAS FOR TRIGGER-RESPONSIVE REGULATION

#13
20240355419
2024-10-24

RAPID ASSEMBLY OF MULTIPLEX GRNA ARRAYS

#14
20240336934
2024-10-10

CRISPR/CAS9-BASED COMPOSITIONS AND METHODS FOR TREATING RETINAL DEGENERATIONS

#15
20240247262
2024-07-25

CRISPR/CAS SYSTEM AND METHOD FOR GENOME EDITING AND MODULATING TRANSCRIPTION

#16
20240124877
2024-04-18

RNA CLEAVAGE-INDUCED TRANSCRIPT STABILIZER AND USES THEREOF

#17
20240102032
2024-03-28

CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF

#18
20230340536
2023-10-26

Methods and compositions for transducing lymphocytes and regulating the activity thereof

#19
20230265422
2023-08-24

EFFICIENT RNA SWITCHES AND RELATED EXPRESSION SYSTEMS

#20
20230257776
2023-08-17

METHODS AND COMPOSITIONS FOR TRANSDUCING LYMPHOCYTES AND REGULATING THE ACTIVITY THEREOF

#21
20230220382
2023-07-13

REGULATION OF GENE EXPRESSION VIA APTAMER-MEDIATED CONTROL OF SELF-CLEAVING RIBOZYMES

#22
20230073250
2023-03-09

Ribozyme-mediated RNA Assembly and Expression

#23
20220380808
2022-12-01

Method for delivering RNA to neurons to treat herpes infections

#24
20210403952
2021-12-30

METHODS AND COMPOSITIONS FOR TRANSDUCING LYMPHOCYTES AND REGULATING THE ACTIVITY THEREOF

#25
20210332368
2021-10-28

Compositions and methods to restore paternal UBE3A gene expression in human Angelman syndrome

#26
20210207169
2021-07-08

VIRAL DELIVERY OF RNA UTILIZING SELF-CLEAVING RIBOZYMES AND CRISPR-BASED APPLICATIONS THEREOF

#27
20210207147
2021-07-08

Compositions and methods for treatment of dominant retinitis pigmentosa

#28
20210139926
2021-05-13

PLANT GENOME EDITING

#29
20210123045
2021-04-29

A YEAST TWO-HYBRID RNA-PROTEIN INTERACTION SYSTEM BASED ON CATALYTICALLY INACTIVATED CRISPR-DCAS9

#30
20200308581
2020-10-01

CRISPR/Cas system and method for genome editing and modulating transcription

#31
20200277601
2020-09-03

SYNTHETIC HAMMERHEAD RIBOZYMES WITH LIGAND-RESPONSIVE TERTIARY INTERACTIONS

#32
20200255835
2020-08-13

COMPOSITIONS AND METHODS FOR REGULATION OF GENE EXPRESSION WITH, AND DETECTION OF, FOLINIC ACID AND FOLATES

#33
20200190540
2020-06-18

GENETIC TARGETING IN NON-CONVENTIONAL YEAST USING AN RNA-GUIDED ENDONUCLEASE

#34
20200181619
2020-06-11

Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation

#35
20200140887
2020-05-07

Viral delivery of RNA utilizing self-cleaving ribozymes and CRISPR-based applications thereof

#36
20200080108
2020-03-12

CRISPR/CAS9-BASED COMPOSITIONS AND METHODS FOR TREATING RETINAL DEGENERATIONS

#37
20200063124
2020-02-27

Methods for RNA promoter identification

#38
20200032253
2020-01-30

Regulation of gene expression via aptamer-mediated control of self-cleaving ribozymes

#39
20190231902
2019-08-01

Method for delivering RNA to neurons to treat herpes infections

#40
20190032054
2019-01-31

RNA cleavage-induced transcript stabilizer and uses thereof

#41
20180326092
2018-11-15

Argonaute protein-double stranded RNA complexes and uses related thereto

#42
20180237781
2018-08-23

Compositions and methods for regulation of gene expression with, and detection of, folinic acid and folates

#43
20180187192
2018-07-05

Synthetic hammerhead ribozymes with ligand-responsive tertiary interactions

#44
20180171385
2018-06-21

ALKB -FACILITATED RNA METHYLATION SEQUENCING (ARM-SEQ)

#45
20180155713
2018-06-07

Methods for RNA promoter identification

#46
20180080022
2018-03-22

Catalytic strands of minimal hammerhead ribozymes and methods of using the same

#47
20180030445
2018-02-01

Compositions and methods using capsids resistant to hydrolases

#48
20170356010
2017-12-14

Methods and compositions for transducing lymphocytes and regulating the activity thereof

#49
20160331716
2016-11-17

Molecular targets for healing or treating wounds

#50
20160177299
2016-06-23

Compositions and methods using capsids resistant to hydrolases

#51
20160046938
2016-02-18

HAMMERHEAD RIBOZYMES

#52
20140302593
2014-10-09

Process for purifying VLPs

#53
20140242114
2014-08-28

cDNA construct of Salmonidae alphavirus

#54
20140228556
2014-08-14

Ribozyme for identifying modification on RNA sequence and RNA cleavage method using same

#55
20130022964
2013-01-24

Use of ribozymes in the detection of adventitious agents

#56
20120321613
2012-12-20

MOLECULAR TARGETS FOR HEALING OR TREATING WOUNDS

#57
20120263691
2012-10-18

Modular aptamer-regulated ribozymes

#58
20120202982
2012-08-09

Compositions and methods for therapy of macular degeneration

#59
20120151614
2012-06-14

Vector utilizing borna disease virus and use thereof

#60
20120149763
2012-06-14

PHARMACEUTICAL COMPOSITION FOR TREATING ADVERSE REACTIONS DUE TO ADMINISTRATION OF SPIEGELMERS

#61
20120058092
2012-03-08

PROCESS FOR THE PREPARATION OF A COMPOSITION OF GENETICALLY MODIFIED HEMATOPOIETIC PROGENITOR CELLS

#62
20110207694
2011-08-25

MAMMALIAN HYPOTHALAMIC NUTRIENT MODULATION OF GLUCOSE METABOLISM

#63
20110064767
2011-03-17

CDNA CONSTRUCT OF SALMONIDAE ALPHAVIRUS

#64
20110046208
2011-02-24

Nucleolar targeting of therapeutics against HIV

#65
20110002892
2011-01-06

Modular aptamer-regulated ribozymes

#66
20100316615
2010-12-16

Antisense Oligonucleotides Against VR1

#67
20100273997
2010-10-28

Ribozyme to cleave coronavirus gene

#68
20100168208
2010-07-01

RNA interference mediated treatment of alzheimer's disease using short interfering nucleic acid (siNA)

#69
20100143892
2010-06-10

Use of ribozymes in the detection of adventitious agents

#70
20100036107
2010-02-11

RNA INTERFERENCE COMPOSITIONS AND METHODS

#71
20100003753
2010-01-07

Multivalent rna nanoparticles for delivery of active agents to a cell

#72
20090233368
2009-09-17

ALLELE SUPPRESSION

#73
20090227659
2009-09-10

Nucleolar targeting of therapeutics against HIV

#74
20090221807
2009-09-03

2' Deoxy-2'-Alkylnucleotide Containing Nucleic Acid

#75
20090197336
2009-08-06

SUPPRESSION OF POLYMORPHIC ALLELES

#76
20090192104
2009-07-30

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#77
20090170197
2009-07-02

Nucleic Acid-Mediated Treatment of Diseases or Conditions Related to Levels of Vascular Endothelial Growth Factor Receptor (VEGF-R)

#78
20090156528
2009-06-18

RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)

#79
20090149407
2009-06-11

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#80
20090131644
2009-05-21

Herpesvirus ribozymes and vectors

#81
20090099119
2009-04-16

RNA INTERFERENCE MEDIATED INHIBITION OF RAS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#82
20090099118
2009-04-16

RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA)

#83
20090099115
2009-04-16

RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA)

#84
20090011402
2009-01-08

Biosensors based on directed assembly of particles

#85
20080317777
2008-12-25

cDNA construct of salmonidae alphavirus

#86
20080317717
2008-12-25

ANTI-HEPATITIS B VIRUS RIBOZYMAL NUCLEIC ACID

#87
20080261277
2008-10-23

pRNA chimera

#88
20080227160
2008-09-18

Circular DNA vectors for synthesis of RNA and DNA

#89
20080207539
2008-08-28

Self-Processing Rna Expression Cassette

#90
20080188430
2008-08-07

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#91
20080108052
2008-05-08

Use of Ribozymes in the Detection of Adventitious Agents

#92
20080064647
2008-03-13

pRNA chimera

#93
20080044394
2008-02-21

Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells

#94
20080033156
2008-02-07

Polycationic compositions for cellular delivery of polynucleotides

#95
20080032942
2008-02-07

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#96
20070249820
2007-10-25

Activatable Ribozymal Purification Constructs and Methods of Use

#97
20070212330
2007-09-13

Nucleic Acid Molecules As Herpanase Potent Inhibitors, Compositions And Methods Of Use Thereof

#98
20070178064
2007-08-02

Antisense IAP nucleobase oligomers and uses thereof

#99
20070161596
2007-07-12

RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA)

#100
20070135371
2007-06-14

Antisense IAP nucleobase oligomers and uses thereof

#101
20070093437
2007-04-26

Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina)

#102
20070087008
2007-04-19

Rab9a, rab11a, and modulators thereof related to infectious disease

#103
20070049544
2007-03-01

Antisense IAP nucleobase oligomers and uses thereof

#104
20070042029
2007-02-22

Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)

#105
20070032445
2007-02-08

Antisense IAP nucleobase oligomers and uses thereof

#106
20070026394
2007-02-01

Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies

#107
20060270621
2006-11-30

Inhibition of hair growth with RNAi targeting desmoglein 4 and nude mRNAs

#108
20060269530
2006-11-30

RNA interference compositions and methods

#109
20060248604
2006-11-02

Adeno-associated virus-delivered ribozyme compositions and methods of use

#110
20060223990
2006-10-05

Synthesis, deprotection, analysis & purification of RNA & ribozymes

#111
20060216824
2006-09-28

Paramyxovirus vector encoding ribozyme and utilization thereof

#112
20060178331
2006-08-10

Antisense oligonucleotides targeting folate receptor alpha, and the use thereof

#113
20060178326
2006-08-10

Ribozyme therapy for the treatment of proliferative skin and eye diseases

#114
20060154271
2006-07-13

Enzymatic nucleic acid treatment of diseases or conditions related to levels of IKK-gamma and PKR

#115
20060142557
2006-06-29

2'-deoxy-2'alkylnucleotide containing nucleic acid

#116
20060142225
2006-06-29

RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)

#117
20060128648
2006-06-15

Genetic suppression and replacement

#118
20060127891
2006-06-15

RNA interference mediated inhibition of MAP kinase gene expression or expression of genes involved in MAP kinase pathway using short interfering nucleic acid (siNA)

#119
20060121466
2006-06-08

Hammerhead ribozymes

#120
20060105977
2006-05-18

Desmoglein 4 is a novel gene involved in hair growth

#121
20060094026
2006-05-04

Nucleic acid enzyme light-up sensor utilizing invasive DNA

#122
20060058252
2006-03-16

Methods and materials for treating human papillomavirus infections

#123
20050288242
2005-12-29

RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)

#124
20050261212
2005-11-24

RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering RNA

#125
20050257277
2005-11-17

Regulation of transcription with a cis-acting ribozyme

#126
20050256068
2005-11-17

RNA interference mediated inhibition of stearoyl-CoA desaturase (SCD) gene expression using short interfering nucleic acid (siNA)

#127
20050250727
2005-11-10

Use of immunomodulating agents

#128
20050239061
2005-10-27

Identification and use of effectors and allosteric molecules for the alteration of gene expression

#129
20050233997
2005-10-20

RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)

#130
20050233344
2005-10-20

RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA)

#131
20050227937
2005-10-13

Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor

#132
20050222400
2005-10-06

Aptamer constructs

#133
20050222064
2005-10-06

Polycationic compositions for cellular delivery of polynucleotides

#134
20050209179
2005-09-22

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#135
20050203040
2005-09-15

RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)

#136
20050202423
2005-09-15

Method for identifying compounds or lead structures against rna target motifs and rna/protein interactions

#137
20050196767
2005-09-08

RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)

#138
20050191638
2005-09-01

RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)

#139
20050187174
2005-08-25

RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)

#140
20050182009
2005-08-18

RNA interference mediated inhibition of NF-Kappa B / REL-A gene expression using short interfering nucleic acid (siNA)

#141
20050176666
2005-08-11

RNA interference mediated inhibition of GPRA and AAA1 gene expression using short interfering nucleic acid (siNA)

#142
20050176664
2005-08-11

RNA interference mediated inhibition of cholinergic muscarinic receptor (CHRM3) gene expression using short interfering nucleic acid (siNA)

#143
20050176663
2005-08-11

RNA interference mediated inhibition of protein tyrosine phosphatase type IVA (PRL3) gene expression using short interfering nucleic acid (siNA)

#144
20050176038
2005-08-11

Polymearase III-based expression of therapeutic RNAs

#145
20050176025
2005-08-11

RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)

#146
20050176024
2005-08-11

RNA interference mediated inhibition of epidermal growth factor receptor (EGFR) gene expression using short interfering nucleic acid (siNA)

#147
20050176017
2005-08-11

Bioreactive allosteric polynucleotides

#148
20050171040
2005-08-04

RNA interference mediated inhibition of cholesteryl ester transfer protein (CEPT) gene expression using short interfering nucleic acid (siNA)

#149
20050170371
2005-08-04

RNA interference mediated inhibition of 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)

#150
20050164968
2005-07-28

RNA interference mediated inhibition of ADAM33 gene expression using short interfering nucleic acid (siNA)

#151
20050164967
2005-07-28

RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)

#152
20050164966
2005-07-28

RNA interference mediated inhibition of type 1 insulin-like growth factor receptor gene expression using short interfering nucleic acid (siNA)

#153
20050159382
2005-07-21

RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)

#154
20050159381
2005-07-21

RNA interference mediated inhibition of chromosome translocation gene expression using short interfering nucleic acid (siNA)

#155
20050159380
2005-07-21

RNA interference mediated inhibition of angiopoietin gene expression using short interfering nucleic acid (siNA)

#156
20050159379
2005-07-21

RNA interference mediated inhibition of gastric inhibitory polypeptide (GIP) and gastric inhibitory polypeptide receptor (GIPR) gene expression using short interfering nucleic acid (siNA)

#157
20050159378
2005-07-21

RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)

#158
20050158735
2005-07-21

RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)

#159
20050153916
2005-07-14

RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)

#160
20050143333
2005-06-30

RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)

#161
20050130181
2005-06-16

RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)

#162
20050124569
2005-06-09

RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)

#163
20050124567
2005-06-09

RNA interference mediated inhibition of TRPM7 gene expression using short interfering nucleic acid (siNA)

#164
20050124566
2005-06-09

RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)

#165
20050119211
2005-06-02

RNA mediated inhibition connexin gene expression using short interfering nucleic acid (siNA)

#166
20050112100
2005-05-26

Sp1 and Sp3 targeted cancer therapies and therapeutics

#167
20050096282
2005-05-05

Adeno-associated virus-delivered ribozyme compositions and methods for the treatment of retinal diseases

#168
20050080031
2005-04-14

Nucleic acid treatment of diseases or conditions related to levels of Ras, HER2 and HIV

#169
20050079610
2005-04-14

RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)

#170
20050075304
2005-04-07

RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)

#171
20050074760
2005-04-07

Enzymatic nucleic acids containing 5'-and/or 3'-cap structures

#172
20050063958
2005-03-24

Process for the preparation of a composition of genetically modified hematopoietic progenitor cells

#173
20050054596
2005-03-10

RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)

#174
20050032733
2005-02-10

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)

#175
20050032726
2005-02-10

Uses of DNA-PK

#176
20050020529
2005-01-27

Delivery construct for antisense nucleic acids and methods of use