Medical treatment

Use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases

Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina)

Modulation of cell phenotype by inhibitory rna

Regulation of food intake by modulation of long-chain fatty acyl-CoA levels in the hypothalamus

Compositions and methods for diagnosing and treating cancers

Method for changing genetic properties of eukaryotic organism

siRNA targeting tumor necrosis factor superfamily member 1A

siRNA targeting complement factor B

siRNA targeting BCL2L1

siRNA targeting KRAS

Pluripotential stem cells

Methods of treating ocular conditions

Method of identifying agents that inhibit the growth of cancer cells

Methods of treatment and diagnosis using modulators of virus-induced cellular gene sequences

Therapeutic methods, compounds and compositions

Human microRNA targets in HIV genome and a method of identification thereof

Rab9a, rab11a, and modulators thereof related to infectious disease

Method for inducing a specific rnai activity in cells and nucleic acids for carrying out said method

FERRITIN AS A THERAPEUTIC TARGET IN ABNORMAL CELLS

Method for reducing HIV viral budding by administering a VPS28-specfic antibody that disrupts Gag-TSG101-VPS28 binding interactions

Multiple RNAi expression cassettes for simultaneous delivery of RNAi agents related to heterozygotic expression patterns

Methods and compositions for the utilization and targeting of osteomimicry

Therapeutic compounds

siRNA targeting survivin

Tumor inhibition by modulating sprouty expression or activity

Novel oligonucleotide compositions and probe sequences useful for detection and analysis of microRNAS and their target mRNAS

Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof

Shc proteins as therapeutic targets in proliferative diseases

Methods and compositions for inhibiting viral infections

Pure miRNA Sample Preparation Method

Method for diagnosing hepatocellular carcinomas

Modulation of hnRNP H and treatment of DM1

Modulation of s6 kinase activity for the treatment of obesity

Micrornas and uses thereof

RNA interference mediated inhibition of 11 beta-hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) gene expression using short interfering nucleic acid siNA

Oligonucleotide inhibiting the expression of star-binding protein (sbp) gene and method therefor

METHOD FOR TREATING PSORIASIS

P2Y4 Receptor transgenic and knockout non-human mammals

Methods for producing microRNAs

RNAi modulation of the Rho-A gene in research models

Methods of inhibiting VEGF-C

iRNA agents targeted to the Rho-A gene

Gp131: methods and compositions for treating cancer

Oligonucleic acid-bearing composite and pharmaceutical composition containing the composite

Bioinformatically detectable group of novel regulatory viral and viral associated oligonucleotides and uses thereof

Functional and hyperfunctional siRNA

Compositions and methods for siRNA inhibition of angiogenesis

Compositions and methods for siRNA inhibition of angiogenesis

COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ANGIOGENESIS

Modulation of hair growth

ES cells having enhanced RNAi effect

Production of reprogrammed cells with restored potential

Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina)

Oligonucleotides directed against a survivin gene and use thereof

Methods for inducing differentiation of undifferentiated mammalian cells into osteoblasts

Functional and hyperfunctional siRNA

Vaccinia virus-related nucleic acids and microRNA

Polypeptide compounds for inhibiting angiogenesis and tumor growth

Methods and compositions for silencing genes without inducing toxicity

Small interfering RNA with improved activity

GLUCOSE TRANSPORT-RELATED GENES, POLYPEPTIDES, AND METHODS OF USE THEREOF

Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same

Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies

RNAi expression constructs

Structural-based inhibitors of the glutathione binding site in aldose reductase, methods of screening therefor and methods of use

Inhibition of Lysyl oxidase for treating tumor growth and diagnostics relating thereto

Methods and compositions for RNA interference

Modulation of endogenous AICAR levels for the treatment of diabetes and obesity

Methods and compositions for the inhibition of stat5 in prostate cancer cells

Antibody against nox1 polypeptide, method of diagnosing cancer with the use of nox1 gene and method of screening cancer growth inhibitor

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Method and means for treatment of osteoarthritis

Diagnosis and treatment of kidney fibrosis and other fibrotic diseases

Methods for modulating bone tissue formation, orthogenic agents and pharmaceutical compositions

RNAi agents for maintenance of stem cells

RNA sequence-specific mediators of RNA interference

RNA sequence-specific mediators of RNA interference

RNA sequence-specific mediators of RNA interference

RNA sequence-specific mediators of RNA interference

Vectorization of dsRNA by cationic particles and topical use

Viral and viral associated miRNAs and uses thereof

Compositions and methods for siRNA inhibition of angiogenesis

Targets for tumor growth inhibition

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Dual functional oligonucleotides for use as anti-viral agents

Inhibition of gene expression using RNA interfering agents

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ANGIOGENESIS

Modulation of negative immune regulators and applications for immunotherapy

Methods and reagents for inhibiting cell proliferation

Methods for determining specificity of RNA silencing and for genetic analysis of the silenced gene or protein

Short interfering nucleic acid hybrids and methods thereof

RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA)

RNA interference mediated ihibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNAi modulation of the BCR-ABL fusion gene and uses thereof

Oligonucleotides comprising a non-phosphate backbone linkage

Compositions and methods for combined therapy of disease

Compositions and methods for siRNA inhibition of angiogenesis

Transgenic plant-derived siRNAs for suppression of influenza virus propagation in mammalian cells

Animal models for demyelination disorders

Methods and compositions for modulating vascular integrity

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Compositions and methods for treatment of prostate and other cancers

Survivin-directed RNA interference-compositions and methods

RNA interference mediated inhibition of B7-H1 gene expression using short interfering nucleic acid (siNA)

Staple type oligonucleotide and drug comprising the same

METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS

Use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Methods of treatment and diagnosis of kaposi's sarcoma (ks) and ks related diseases

Method of detecting target base sequence of rna interference, method of designing polynucleotide base sequence causing rna interference, method of constructing double-stranded polynucleotide, method of regulating gene expression, base sequence processing apparatus, program for running base sequence processing method on comp

Potent inhibition of influenza virus by specifically designed short interfering RNA

RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)

RNA interference compositions and methods

Modulation of cytokine signaling regulators and applications for immunotherapy

Small interference RNA gene therapy

Oncogene HOXB13 and its siRNAs

Composition for treatment or prevention of endometrial cancer and method of preventing or treating endometrial cancer using the composition

Livin-specific sirnas for the treatment of therapy-resistant tumors

Mule: Mcl-1 ubiquitination ligase E3

System and method for identification of MicroRNA precursor sequences and corresponding mature MicroRNA sequences from genomic sequences

Methods and constructs for evaluation of rnai targets and effector molecules

Inhibitors of ribonucleotide reductase subunit 2 and uses thereof

Inhibition of SARS-associated coronavirus (SCoV) infection and replication by RNA interference

RNAi modulation of RSV and therapeutic uses thereof

Use of IL-17F in diagnosis and therapy of airway inflammation

Methods and sequences to suppress primate huntington gene expression

Cell lines and host nucleic acid sequences related to infectious disease

Use of sirnas for gene silencing in antigen presenting cells

Oligomeric compounds and compositions for use in modulation of pri-mirnas

Retroviral vectors for delivery of interfering RNA

FBL2-specific agents as modulators of Flaviviridae RNA replication

Methods of treatment of feeding disorders or disorders of glucose uptake and for modifying metabolism and identifying therapeutic reagents therefor

Treatment of Duchenne muscular dystrophy with myoblasts expressing dystrophin and treated to block myostatin signaling

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

Method for down-regulating gene expression in fungi

Rna interference mediated treatment of alzheimer's disease using short interfering nucleic acid (sina)

Regulation of gene expression by dna interference

Micro-RNA's that regulate muscle cells

Targeted therapy via targeted delivery of energy susceptible nanoscale magnetic particles

RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)

Oligomeric compounds for use in gene modulation

Means for preventing and treating cellular death and their biological applications

Protein Arginine N-Methyltransferase 2 (PRMT-2)

Methods for attenuating dengue virus infection

Transcription factor RNA interference reagents and methods of use thereof

Methods and compositions for the treatment of eye disorders with increased intraocular pressure

Small interference RNA (siRNA) molecules for modulating superoxide dismutase (SOD)

Silencing of tgf-beta receptor type II expression by sirna

Highly functional short hairpin RNA

RNAi-mediated inhibition of frizzled related protein-1 for treatment of glaucoma

IRNA agents targeting VEGF

Regulation of gene expression

Inhibition of SHIP to enhance stem cell harvest and transplantation

Methods and compositions for modulating Necdin function

Sirna mediated gene silencing in transgenic animals

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)

Chemically modified double stranded nucleic acid molecules that mediate RNA interference

Method of stimulating an immune response and inhibiting expression of a gene using an oligonucleotide

Therapeutic uses of inhibitors of RTP801

siRNA expression system

Group of nucleic acid fragments for prevention of HIV infection or AIDS and the usage thereof

RNAi modulation of the Nogo-L or Nogo-R gene and uses thereof

RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)

Inducible small RNA expression constructs for targeted gene silencing

RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA)

Methods of down regulating target gene expression in vivo by introduction of interfering rna

Methods and compositions for cancer treatment

Means for regulating the expression of human isoforms of ant

Antigene oligomers inhibit transcription

HIV TEV compositions and methods of use

Methods and agents for regulating angiotensin activity

Compositions and methods for short interfering nucleic acid inhibition of Na1.8

Reagents, methods and systems to suppress phospholamban expression

Target validation assay

Methods and sequences to suppress pro-inflamatory cytokine actions locally to treat pain

RNAi expression constructs with liver-specific enhancer/promoter

Molecular method to augment RNA mediated gene silencing

Inhibition of E3-ubiquitin ligase HAKAI for treatment of proliferative disorders

Methods for identifying chemotherapeutic resistance in non-hematopoietic tumors

Systems and methods for identifying miRNA targets and for altering miRNA and target expression

Therapies for cancer using RLIP76

Double-stranded and single-stranded RNA molecules with 5 ' triphosphates and their use for inducing interferon

Use of antisense oligonucleotides or siRNA to suppress expression of eIF-5A1

Devices, systems and methods for improving and/or cognitive function through brain delivery of siRNA

Inhibition of gene expression by delivery of specially selected double stranded or other forms of small interfering RNA precursors enabling the formation and function of small interfering RNA in vivo and in vitro

Lipophilic derivatives of double-stranded ribonucleic acid

Inhibiting HER2 shedding with matrix metalloprotease antagonists

Method to trigger RNA interference

RNAi-mediated inhibition of ocular targets

Methods for reducing amyloid beta levels

RNAi-mediated inhibition of ocular hypertension targets

RNAi inhibition of serum amyloid a for treatment of glaucoma

Thio-siRNA aptamers

Categorization of microbial communities

Compositions and methods of treating fibrotic disorders

Protecting cell therapy for neurological disorders including Parkinson's disease

Polynucleotides targeted against the extended 5′-UTR region of argininosuccinate synthase and uses thereof

RNAi modulation of RSV and therapeutic uses thereof

Oligonucleotide based therapeutics

RNAi inhibition of CTGF for treatment of ocular disorders

RNAi modulation of MLL-AF4 and uses thereof

Process for producing sirna

RNA-interference by single-stranded RNA molecules

High throughput assay for cancer cell growth inhibition

Apparatus and system having dry control gene silencing compositions

Immunomodulation using altered dendritic cells

Eukaryotic genes involved in adult lifespan regulation

Modulation of glucocorticoid receptor expression

Influenza therapeutic

RNA interference mediated inhibition hairless of (HR) gene expression using short interfering nucleic acid (siNA)

Methods of designing small interfering RNAs, antisense polynucleotides, and other hybridizing polynucleotides

Compositions and methods to inhibit cell loss by using inhibitors of BAG

Use of apoptosis-specific eIF-5A siRNAs and antisense polynucleotides to inhibit/suppress an inflammatory response

Nonsense-mediated mrna decay

NADPH oxidase inhibition pharmacotherapies for obstructive sleep apnea syndrome and its associated morbidities

Efficient gene suppression using a transfer RNA promoter in herpes virus vectors to deliver small interference RNAs

Enzymatic nucleic acid treatment of diseases or conditions related to levels of IKK-gamma and PKR

RNA interference mediated inhibition of histone deacetylase (HDAC) gene expression using short interfering nucleic acid (siNA)

Method of evaluating compound efficacious in treating obesity

Inhibition of stress-induced ligand-dependent egfr activation

Methods and compositions concerning siRNA's as mediators of RNA interference

RNA interference mediated inhibition of cholesteryl ester transfer protein (CETP) gene expression using short interfering nucleic acid (siNA)

RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)

Selective inhibition of rock1 in cardiac therapy

Methods and compositions for RNA interference

Down-regulation of target-gene with pei/single-stranded oligoribonucleotide complexes

Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended siRNA

Use of RNA trans-splicing for generation of interfering RNA molecules

siRNA silencing of apolipoprotein B

Treatment of diabetes using antibodies to IL-23, IL-23 receptor and IL-17

Treatment of cancer by simultaneous inhibiton of BRAF and restoration or mimicry of p16INK4A activity

Allele-specific RNA interference

Use of mob-5 in pain

RNA interference mediated inhibition of MAP kinase gene expression or expression of genes involved in MAP kinase pathway using short interfering nucleic acid (siNA)

Variants of glycogen synthase kinase 3 and uses thereof

Inducible systems and methods for controlling siRNA expression

Effective and stable DNA enzymes

Receptor and screening methods

Use of cd 137 antagonists for the treatment of tumors

Neuropilin-1 inhibitors

Apparatus and system having dry gene silencing compositions

Therapeutic RNAi agents for treating psoriasis

Therapeutic RNAi agents for treating restenosis

Methods and compositions for treating cellular proliferative diseases

Apparatus and system having dry gene silencing pools

Method of determining a cellular response to a biological agent

Treatment of cancer using TLR3 agonists

Method and system for biasing cellular development

Synergistic inhibition of VEGF and modulation of the immune response

RNAi modulation of ApoB and uses thereof

Aptamer-mediated intracellular delivery of therapeutic oligonucleotides

Modulation of deubiquitinase family members

Therapies for the regulation of insulin and glucose using RLIP76

Therapies for seizure disorders using RLIP76

Methods and compositions for inhibiting the function of polynucleotide sequences

Nuclease resistant double-stranded ribonucleic acid

Inhibition of apoptosis-specific eIF-5A ("eIF-5A1") with antisense oligonucleotides and siRNA as anti-inflammatory therapeutics

Compositions and methods for treating cancer using compositions comprising an inhibitor of endothelin receptor activity

Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases

RNA silencing in animals as an antiviral defense

Macrocyclic chelators for gene-silencing or gene disruption

iRNA agents targeting VEGF

RNAi modulation of RSV, PIV and other respiratory viruses and uses thereof

RNAi modulation of RSV, PIV and other respiratory viruses and uses thereof

Aptamer regulated nucleic acids and uses thereof

Expression system for stem-loop rna molecule having rnai effect

RNA interference in respiratory epitheial cells

Methods for delivery of nucleic acids

Conjugates for use in hepatocyte free uptake assays

B7-H1 and methods of diagnosis, prognosis, and treatment of cancer

Snornai-small nucleolar RNA degradation by RNA interference in trypanosomatids

Methods and compositions for the diagnosis and treatment of cyclin A-1 associated conditions

Method and compositions for RNA interference

Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules

IKKalpha and IKKbeta specific inhibitors

Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases

Methods and compositions for mediating gene silencing

Methods of reducing an immune response

In vivo inhibition of hepatitis B virus

MicroRNA vectors

Chemically modified oligonucleotides

Oligoribonucleotides for the treatment of degenerative skin conditions by RNA interference

RNAi-based therapeutics for allergic rhinitis and asthma

Cell specific gene silencing using cell-specific promoters in vitro and in vivo

Administration of FGF2 for treamtent of anxiety

ADAR1 antiviral pathway

RNA interference in avians

Induction of methylation of CpG sequences by dsRNAS in mammalian cells