ClassID:

109178

C12N2310/332 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Chemical structure of the base Abasic residue

Recent Application in this class:
#1
20260109728
2026-04-23

IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE

#2
20260098263
2026-04-09

MODIFIED DOUBLE-STRANDED RNA AGENTS

#3
20260043025
2026-02-12

RNAi Agents And Compositions for Inhibiting Expression of Apolipoprotein C-III (APOC3)

#4
20250388897
2025-12-25

NUCLEIC ACID COMPOUNDS

#5
20250354148
2025-11-20

DUAL-ACTING siRNA BASED MODULATION OF C9orf72

#6
20250320502
2025-10-16

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE THEREOF

#7
20250171785
2025-05-29

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE

#8
20250171544
2025-05-29

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

#9
20250163417
2025-05-22

COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED

#10
20250075205
2025-03-06

AFFINITY REAGENT, MARKER AND METHOD FOR ANALYSING A BIOLOGICAL SAMPLE

#11
20250075204
2025-03-06

AFFINITY REAGENT, MARKER AND METHOD FOR ANALYSING A BIOLOGICAL SAMPLE

#12
20250066791
2025-02-27

RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#13
20250034572
2025-01-30

MODIFIED DOUBLE-STRANDED RNA AGENTS

#14
20250002913
2025-01-02

NUCLEIC ACIDS CONTAINING ABASIC NUCLEOSIDES

#15
20240425864
2024-12-26

ANTISENSE OLIGONUCLEOTIDES HAVING ONE OR MORE ABASIC UNITS

#16
20240409942
2024-12-12

MODIFIED DOUBLE-STRANDED RNA AGENTS

#17
20240287566
2024-08-29

NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES

#18
20240279658
2024-08-22

DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO

#19
20240254480
2024-08-01

MODIFIED NUCLEIC ACID INHIBITING MICRO RNA, AND USE THEREOF

#20
20240247271
2024-07-25

RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#21
20240218363
2024-07-04

OPTIMIZED 2'- MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE

#22
20240191229
2024-06-13

RNA SILENCING AGENTS AND METHODS OF USE

#23
20240093199
2024-03-21

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE

#24
20240018519
2024-01-18

Stabilized saRNA Compositions and Methods of Use

#25
20240011032
2024-01-11

SNCA IRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING SNCA-ASSOCIATED NEURODEGENERATIVE DISEASES

#26
20230407311
2023-12-21

NUCLEIC ACIDS CONTAINING ABASIC NUCLEOTIDES

#27
20230323350
2023-10-12

RNAi Agents And Compositions for Inhibiting Expression of Apolipoprotein C-III (APOC3)

#28
20230183701
2023-06-15

Modified double-stranded RNA agents

#29
20230159923
2023-05-25

RIG-I Agonists and Methods of Using Same

#30
20230110876
2023-04-13

MODIFIED DOUBLE-STRANDED RNA AGENTS

#31
20230095192
2023-03-30

SYNTHETIC AGONISTS OF DNA-PK AND THEIR USE

#32
20230030119
2023-02-02

RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#33
20230013022
2023-01-19

RNAi Agents for Inhibiting Expression of Beta-ENaC, Compositions Thereof, and Methods of Use

#34
20220411797
2022-12-29

Twist signaling inhibitor compositions and methods of using the same

#35
20220396799
2022-12-15

THERAPEUTIC INHIBITION OF LACTATE DEHYDROGENASE AND AGENTS THEREFOR

#36
20220389424
2022-12-08

Modified double-stranded RNA agents

#37
20220380772
2022-12-01

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#38
20220348929
2022-11-03

CRISPR ABASIC RESTRICTED NUCLEOTIDES AND CRISPR ACCURACY VIA ANALOGS

#39
20220324984
2022-10-13

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

#40
20220275366
2022-09-01

RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (SINA)

#41
20220267770
2022-08-25

COMPOSITIONS AND METHODS OF USING C/EBP ALPHA SARNA

#42
20220106388
2022-04-07

HIGH VISCOSITY MACROMOLECULAR COMPOSITIONS FOR TREATING OCULAR CONDITIONS

#43
20220056448
2022-02-24

Modified double-stranded RNA agents

#44
20220056069
2022-02-24

IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE

#45
20220033817
2022-02-03

Targeting Ligands

#46
20220017906
2022-01-20

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE THEREOF

#47
20220002727
2022-01-06

MODIFIED DOUBLE-STRANDED RNA AGENTS

#48
20210403917
2021-12-30

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE

#49
20210340535
2021-11-04

Dual-acting siRNA based modulation of C9orf72

#50
20210317452
2021-10-14

SERPINA1 iRNA compositions and methods of use thereof

#51
20210238602
2021-08-05

RNAi Agents And Compositions for Inhibiting Expression of Angiopoietin-Like 3 (ANGPTL3), And Methods Of Use

#52
20210238594
2021-08-05

Compositions and methods for improving strand biased

#53
20210230596
2021-07-29

RIG-I Agonists and Methods of Using Same

#54
20210180068
2021-06-17

Therapeutic inhibition of lactate dehydrogenase and agents therefor

#55
20210179720
2021-06-17

Nucleic acid-polypeptide compositions and uses thereof

#56
20210108212
2021-04-15

RNAi constructs for inhibiting ASGR1 expression and methods of use thereof

#57
20210087219
2021-03-25

OLIGONUCLEOTIDES COMPRISING ACYCLIC AND ABASIC NUCLEOSIDES AND ANALOGS

#58
20210041470
2021-02-11

FUNCTIONAL LIGANDS TO OPIOIDS AND OPIOID METABOLITES

#59
20210017519
2021-01-21

Modified double-stranded RNA agents

#60
20200332299
2020-10-22

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (SINA)

#61
20200318119
2020-10-08

Compositions and Methods for Inhibiting Expression of the PCSK9 Gene

#62
20200299690
2020-09-24

RNAi agents and compositions for inhibiting expression of apolipoprotein C-III (APOC3)

#63
20200208152
2020-07-02

STABILIZED SARNA COMPOSITIONS AND METHODS OF USE

#64
20200123261
2020-04-23

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

#65
20200080087
2020-03-12

Twist signaling inhibitor compositions and methods of using the same

#66
20200080085
2020-03-12

Serpina1 iRNA compositions and methods of use thereof

#67
20190330639
2019-10-31

RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#68
20190323014
2019-10-24

Therapeutic inhibition of lactate dehydrogenase and agents therefor

#69
20190309306
2019-10-10

RNAi constructs for inhibiting ASGR1 expression and methods of use thereof

#70
20190256849
2019-08-22

Targeting ligands

#71
20190241893
2019-08-08

Modified double-stranded RNA agents

#72
20190241891
2019-08-08

Modified double-stranded RNA agents

#73
20190078089
2019-03-14

RNAi agents and compositions for inhibiting expression of angiopoietin-like 3 (ANGPTL3), and methods of use

#74
20190078088
2019-03-14

RNAi agents and compositions for inhibiting expression of apolipoprotein C-III (APOC3)

#75
20190062437
2019-02-28

Nucleic acid-polypeptide compositions and uses thereof

#76
20190062436
2019-02-28

Nucleic acid-polypeptide compositions and uses thereof

#77
20190023732
2019-01-24

Oligonucleotides

#78
20180346910
2018-12-06

Serpina1 iRNA compositions and methods of use thereof

#79
20180312536
2018-11-01

Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use

#80
20180216115
2018-08-02

Compositions and methods for inhibiting expression of the PCSK9 gene

#81
20180195071
2018-07-12

RNA interference mediated inhibition of hepatitis B Virus (HBV) gene expression using short interfering nucleic acid (siNA)

#82
20180171321
2018-06-21

PLATFORM FOR A NON-NATURAL AMINO ACID INCORPORATION INTO PROTEINS

#83
20180112216
2018-04-26

Segmented micro RNA mimetics

#84
20180100154
2018-04-12

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#85
20180080024
2018-03-22

Single-stranded RNAi agents containing an internal, non-nucleic acid spacer

#86
20180064819
2018-03-08

Targeting ligands

#87
20180057814
2018-03-01

Compositions and methods for inhibition of nucleic acids function

#88
20180030454
2018-02-01

RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)

#89
20170306332
2017-10-26

Therapeutic inhibition of lactate dehydrogenase and agents therefor

#90
20170275626
2017-09-28

Modified double-stranded RNA agents

#91
20170233733
2017-08-17

Twist signaling inhibitor compositions and methods of using the same

#92
20170114342
2017-04-27

Serpina1 iRNA compositions and methods of use thereof

#93
20170009232
2017-01-12

Compositions and methods for inhibition of nucleic acids function

#94
20160348117
2016-12-01

Compositions and methods for inhibiting expression of the PCSK9 gene

#95
20160348115
2016-12-01

CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity

#96
20160304878
2016-10-20

Nucleic acid inducing RNA interference modified for preventing off-target, and use thereof

#97
20160298123
2016-10-13

RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)

#98
20160257962
2016-09-08

RNA INTERFERENCE MEDIATED INHIBITION OF ISOCITRATE DEHYDROGENASE (IDH1) GENE EXPRESSION

#99
20160244756
2016-08-25

Formats for organic compounds for use in RNA interference

#100
20150376613
2015-12-31

Segmented micro RNA mimetics

#101
20150322433
2015-11-12

Post-synthetic orthogonal amidation plus metal catalyzed azide-alkyne cycloaddition click chemistry on siRNA

#102
20150259675
2015-09-17

Short interfering ribonucleic acid (siRNA) for oral administration

#103
20150166992
2015-06-18

Compositions and methods for inhibition of nucleic acids function

#104
20150159154
2015-06-11

Oligonucleotide compounds comprising non-nucleotide overhangs

#105
20140350075
2014-11-27

Compositions and methods for inhibiting expression of the PCSK9 gene

#106
20140350071
2014-11-27

Serapina1 iRNA compositions and methods of use thereof

#107
20140163213
2014-06-12

CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity

#108
20140127255
2014-05-08

Chimeric immunomodulatory compounds and methods of using the same-IV

#109
20140094503
2014-04-03

RNA interference mediated inhibition of isocitrate dehydrogenase (IDH1) gene expression

#110
20130230923
2013-09-05

Short interfering ribonucleic acid (siRNA) for oral administration

#111
20130225652
2013-08-29

Segmented micro RNA mimetics

#112
20130172399
2013-07-04

Selective inhibition of polyglutamine protein expression

#113
20130165500
2013-06-27

RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)

#114
20130130378
2013-05-23

Oligonucleotides comprising acyclic and abasic nucleosides and analogs

#115
20130035368
2013-02-07

Oligonucleotide compounds comprising non-nucleotide overhangs

#116
20130012567
2013-01-10

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#117
20120231039
2012-09-13

Chimeric immunomodulatory compounds and methods of using the same-IV

#118
20120148664
2012-06-14

CHEMICAL MODIFICATIONS MOTIFS FOR MIRNA INHIBITORS AND MIMETICS

#119
20120142011
2012-06-07

Modified siNA

#120
20120029053
2012-02-02

Short interfering ribonucleic acid (siRNA) for oral administration

#121
20120029052
2012-02-02

Short interfering ribonucleic acid (siRNA) for oral administration

#122
20120022139
2012-01-26

Short interfering ribonucleic acid (siRNA) for oral administration

#123
20110313022
2011-12-22

Compositions and methods for diminishing viral infection and inflammation associated with viral infection

#124
20110288155
2011-11-24

SIRNA COMPOUNDS AND METHODS OF USE THEREOF

#125
20110251261
2011-10-13

Compositions and methods for inhibition of nucleic acids function

#126
20110230542
2011-09-22

Compositions and methods for inhibiting expression of the PCSK9 gene

#127
20110223665
2011-09-15

ENHANCEMENT OF siRNA SILENCING ACTIVITY USING UNIVERSAL BASES OR MISMATCHES IN THE SENSE STRAND

#128
20110171209
2011-07-14

Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9

#129
20110166198
2011-07-07

RNA COMPOSITIONS FOR MODULATING IMMUNE RESPONSE

#130
20110112168
2011-05-12

Double-stranded RNA directed to CASP2 and methods of use thereof

#131
20110105591
2011-05-05

siRNA compounds for inhibiting NRF2

#132
20110065778
2011-03-17

RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)

#133
20110059067
2011-03-10

MODULATION OF OLIGONUCLEOTIDE CPG-MEDIATED IMMUNE STIMULATION BY POSITIONAL MODIFICATION OF NUCLEOSIDES

#134
20100305191
2010-12-02

RNA INTERFERENCE MEDIATED INHIBITION OF ADENOSINE A1 RECEPTOR (ADORA1) GENE EXPRESSION USING SHORT INTERFERING RNA

#135
20100228018
2010-09-09

RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#136
20100197763
2010-08-05

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#137
20100168208
2010-07-01

RNA interference mediated treatment of alzheimer's disease using short interfering nucleic acid (siNA)

#138
20100166780
2010-07-01

CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity

#139
20100152278
2010-06-17

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#140
20100137405
2010-06-03

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#141
20100120895
2010-05-13

RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#142
20100099750
2010-04-22

RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)

#143
20100099743
2010-04-22

RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)

#144
20100015707
2010-01-21

Short interfering ribonucleic acid (siRNA) with improved pharmacological properties

#145
20090317480
2009-12-24

Chimeric immunomodulatory compounds and methods of using the same-II

#146
20090299045
2009-12-03

RNA Interference Mediated Inhibition Of Interleukin and Interleukin Gene Expression Using Short Interfering Nucleic Acid (siNA)

#147
20090264636
2009-10-22

Conjugates and compositions for cellular delivery

#148
20090247613
2009-10-01

RNA INTERFERENCE MEDIATED INHIBITION OF B-CELL CLL/LYMPHOMA-2 (BCL2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#149
20090247606
2009-10-01

RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA)

#150
20090239931
2009-09-24

RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#151
20090216003
2009-08-27

Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) and process for the preparation of TINA

#152
20090192113
2009-07-30

Interfering RNA duplex having blunt-ends and 3′-modifications

#153
20090192104
2009-07-30

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#154
20090162349
2009-06-25

METHOD FOR PREVENTION OR TREATMENT OF DISEASES OR DISORDERS RELATED TO EXCESSIVE FORMATION OF VASCULAR TISSUE OR BLOOD VESSELS

#155
20090156528
2009-06-18

RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)

#156
20090149408
2009-06-11

RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)

#157
20090149407
2009-06-11

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#158
20090137512
2009-05-28

RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)

#159
20090137511
2009-05-28

RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (SINA)

#160
20090137509
2009-05-28

RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATION CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#161
20090137508
2009-05-28

RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)

#162
20090099120
2009-04-16

RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)

#163
20090099119
2009-04-16

RNA INTERFERENCE MEDIATED INHIBITION OF RAS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#164
20090099118
2009-04-16

RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA)

#165
20090099115
2009-04-16

RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA)

#166
20090093438
2009-04-09

RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA)

#167
20090093437
2009-04-09

RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)

#168
20090023676
2009-01-22

RNA Interference Mediated Inhibition of MAP Kinase Gene Expression or Expression of Genes Involved in MAP Kinase Pathway Using Short Interfering Nucleic Acid (SiNA)

#169
20090023675
2009-01-22

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#170
20080268051
2008-10-30

High viscosity macromolecular compositions for treating ocular conditions

#171
20080249294
2008-10-09

RNA Interference Mediated Inhibition of Gene Expression Using Short Interfering Nucleic Acid (siNA)

#172
20080214489
2008-09-04

Aptamer-mediated intracellular delivery of oligonucleotides

#173
20080188430
2008-08-07

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#174
20080181909
2008-07-31

Chimeric immunomodulatory compounds and methods of using the same

#175
20080113930
2008-05-15

Compositions and methods for inhibiting expression of the PCSK9 gene

#176
20080033156
2008-02-07

Polycationic compositions for cellular delivery of polynucleotides

#177
20080032942
2008-02-07

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#178
20070270360
2007-11-22

Rna Interference Mediated Inhibition of Severe Acute Respiratory Syndrome (Sars) Gene Expression Using Short Interfering Nucleic Acid

#179
20070203084
2007-08-30

Interfering Rna Duplex Having Blunt-Ends And 3'-Modifications

#180
20070185043
2007-08-09

Rna interference mediated inhibition of nogo and nogo receptor gene expression using short interfering nucleic acid (sina)

#181
20070161596
2007-07-12

RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA)

#182
20070093437
2007-04-26

Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina)

#183
20070049550
2007-03-01

Chimeric immunomodulatory compounds and methods of using the same—IV

#184
20070042029
2007-02-22

Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)

#185
20070032441
2007-02-08

Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina)

#186
20070026394
2007-02-01

Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies

#187
20060217332
2006-09-28

RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)

#188
20060160757
2006-07-20

RNA interference mediated inhibition hairless of (HR) gene expression using short interfering nucleic acid (siNA)

#189
20060154870
2006-07-13

Method for prevention or treatment of diseases or disorders related to excessive formation of vascular tissue or blood vessels

#190
20060154271
2006-07-13

Enzymatic nucleic acid treatment of diseases or conditions related to levels of IKK-gamma and PKR

#191
20060142556
2006-06-29

Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides

#192
20060142225
2006-06-29

RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)

#193
20060127891
2006-06-15

RNA interference mediated inhibition of MAP kinase gene expression or expression of genes involved in MAP kinase pathway using short interfering nucleic acid (siNA)

#194
20060105975
2006-05-18

Aptamer-mediated intracellular delivery of therapeutic oligonucleotides

#195
20060025361
2006-02-02

RNA interference mediated inhibition of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)

#196
20060019913
2006-01-26

RNA interference mediated inhibtion of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)

#197
20050288242
2005-12-29

RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)

#198
20050282188
2005-12-22

RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)

#199
20050261219
2005-11-24

RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)

#200
20050261212
2005-11-24

RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering RNA

#201
20050256068
2005-11-17

RNA interference mediated inhibition of stearoyl-CoA desaturase (SCD) gene expression using short interfering nucleic acid (siNA)

#202
20050233997
2005-10-20

RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)

#203
20050233344
2005-10-20

RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA)

#204
20050222064
2005-10-06

Polycationic compositions for cellular delivery of polynucleotides

#205
20050209182
2005-09-22

Nucleic acid mediated inhibition of enterococcus infection and cytolysin toxin activity

#206
20050209179
2005-09-22

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#207
20050203040
2005-09-15

RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)

#208
20050196767
2005-09-08

RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)

#209
20050191638
2005-09-01

RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)

#210
20050187174
2005-08-25

RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)

#211
20050182009
2005-08-18

RNA interference mediated inhibition of NF-Kappa B / REL-A gene expression using short interfering nucleic acid (siNA)

#212
20050182008
2005-08-18

RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA)

#213
20050182007
2005-08-18

RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)

#214
20050182006
2005-08-18

RNA interference mediated inhibition of protein kinase C alpha (PKC-alpha) gene expression using short interfering nucleic acid (siNA)

#215
20050176666
2005-08-11

RNA interference mediated inhibition of GPRA and AAA1 gene expression using short interfering nucleic acid (siNA)

#216
20050176664
2005-08-11

RNA interference mediated inhibition of cholinergic muscarinic receptor (CHRM3) gene expression using short interfering nucleic acid (siNA)

#217
20050176663
2005-08-11

RNA interference mediated inhibition of protein tyrosine phosphatase type IVA (PRL3) gene expression using short interfering nucleic acid (siNA)

#218
20050176038
2005-08-11

Polymearase III-based expression of therapeutic RNAs

#219
20050176025
2005-08-11

RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)

#220
20050176024
2005-08-11

RNA interference mediated inhibition of epidermal growth factor receptor (EGFR) gene expression using short interfering nucleic acid (siNA)

#221
20050176018
2005-08-11

Chemically modified double stranded nucleic acid molecules

#222
20050171040
2005-08-04

RNA interference mediated inhibition of cholesteryl ester transfer protein (CEPT) gene expression using short interfering nucleic acid (siNA)

#223
20050170371
2005-08-04

RNA interference mediated inhibition of 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)

#224
20050164968
2005-07-28

RNA interference mediated inhibition of ADAM33 gene expression using short interfering nucleic acid (siNA)

#225
20050164967
2005-07-28

RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)

#226
20050164966
2005-07-28

RNA interference mediated inhibition of type 1 insulin-like growth factor receptor gene expression using short interfering nucleic acid (siNA)

#227
20050164224
2005-07-28

RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)

#228
20050159382
2005-07-21

RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)

#229
20050159381
2005-07-21

RNA interference mediated inhibition of chromosome translocation gene expression using short interfering nucleic acid (siNA)

#230
20050159380
2005-07-21

RNA interference mediated inhibition of angiopoietin gene expression using short interfering nucleic acid (siNA)

#231
20050159379
2005-07-21

RNA interference mediated inhibition of gastric inhibitory polypeptide (GIP) and gastric inhibitory polypeptide receptor (GIPR) gene expression using short interfering nucleic acid (siNA)

#232
20050159378
2005-07-21

RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)

#233
20050159376
2005-07-21

RNA interference mediated inhibition 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)

#234
20050158735
2005-07-21

RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)

#235
20050153916
2005-07-14

RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)

#236
20050153915
2005-07-14

RNA interference mediated inhibition of early growth response gene expression using short interfering nucleic acid (siNA)

#237
20050153914
2005-07-14

RNA interference mediated inhibition of MDR P-glycoprotein gene expression using short interfering nucleic acid (siNA)

#238
20050143333
2005-06-30

RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)

#239
20050137155
2005-06-23

RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)

#240
20050137153
2005-06-23

RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)

#241
20050136436
2005-06-23

RNA interference mediated inhibition of G72 and D-amino acid oxidase (DAAO) gene expression using short interfering nucleic acid (siNA)

#242
20050130181
2005-06-16

RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)

#243
20050124569
2005-06-09

RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)

#244
20050124568
2005-06-09

RNA interference mediated inhibition of acetyl-CoA-carboxylase gene expression using short interfering nucleic acid (siNA)

#245
20050124567
2005-06-09

RNA interference mediated inhibition of TRPM7 gene expression using short interfering nucleic acid (siNA)

#246
20050124566
2005-06-09

RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)

#247
20050119212
2005-06-02

RNA interference mediated inhibition of FAS and FASL gene expression using short interfering nucleic acid (siNA)

#248
20050119211
2005-06-02

RNA mediated inhibition connexin gene expression using short interfering nucleic acid (siNA)

#249
20050096284
2005-05-05

RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)

#250
20050080031
2005-04-14

Nucleic acid treatment of diseases or conditions related to levels of Ras, HER2 and HIV

#251
20050079610
2005-04-14

RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)

#252
20050075304
2005-04-07

RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)

#253
20050070497
2005-03-31

RNA interference mediated inhibtion of tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)

#254
20050054598
2005-03-10

RNA interference mediated inhibition hairless (HR) gene expression using short interfering nucleic acid (siNA)

#255
20050054596
2005-03-10

RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)

#256
20050048529
2005-03-03

RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)

#257
20050043263
2005-02-24

Use of double-stranded ribonucleic acid for inducing cell lysis

#258
20050032733
2005-02-10

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)

#259
20050020525
2005-01-27

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#260
20050014172
2005-01-20

RNA interference mediated inhibition of muscarinic cholinergic receptor gene expression using short interfering nucleic acid (siNA)