Patents-Review.com
ClassID:

109196 ⎘

C12N2310/3515 - page 3 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Chemical structure; Nature of the modification; Conjugate Lipophilic moiety, e.g. cholesterol

Recent Application in this class:
#601
20180371465
2018-12-27

Polynucleotide agents targeting programmed cell death 1 ligand 1 (PD-L1) and methods of use thereof

 #602
20180371464
2018-12-27

RNA interference in dermal and fibrotic indications

 #603
20180362978
2018-12-20

Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes

 #604
20180360866
2018-12-20

MicroRNA (miRNA) and downstream targets for diagnostic and therapeutic purposes

 #605
20180355362
2018-12-13

Organic compositions to treat beta-ENaC-related diseases

 #606
20180327748
2018-11-15

RNA interference in skin indications

 #607
20180327741
2018-11-15

Nucleic acid nanostructures with core motifs

 #608
20180320181
2018-11-08

Chimeric double-stranded nucleic acid

 #609
20180312847
2018-11-01

Methods of treatment using antisense oligomers and conjugates targeting PCSK9

 #610
20180312846
2018-11-01

Manufacture of antisense oligomers and conjugates targeting PCSK9

 #611
20180312841
2018-11-01

RIG-I ligands and methods for producing them

 #612
20180312536
2018-11-01

Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use

 #613
20180305696
2018-10-25

METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS

 #614
20180298379
2018-10-18

SMALL INTERFERING RNA MODIFICATION METHOD BY COMBINING WITH ISONUCLEOSIDE MODIFICATION, TERMINAL PEPTIDE CONJUGATION AND CATIONIC LIPOSOMES, AND PREPARATION

 #615
20180282725
2018-10-04

Lipid formulated compositions and methods for inhibiting expression of Serum Amyloid A gene

 #616
20180273955
2018-09-27

Sterol regulatory element binding protein (SREBP) chaperone (SCAP) iRNA compositions and methods of use thereof

 #617
20180273953
2018-09-27

Compositions and methods for modulating apolipoprotein (a) expression

 #618
20180273952
2018-09-27

Compositions and methods for modulating apolipoprotein C-III expression

 #619
20180273947
2018-09-27

Programmed cell death 1 ligand 1 (PD-L1) iRNA compositions and methods of use thereof

 #620
20180258430
2018-09-13

Compositions and Methods for Inhibiting Gene Expression of Alpha-1 AntiTrypsin

 #621
20180258427
2018-09-13

Modified iRNA agents

 #622
20180256729
2018-09-13

Conjugated antisense compounds and their use

 #623
20180251766
2018-09-06

Targeting microRNAs for metabolic disorders

 #624
20180251764
2018-09-06

Oligonucleotide conjugates

 #625
20180245077
2018-08-30

COMPOSITIONS AND METHODS FOR TREATING HYPERTRIGLYCERIDEMIA

 #626
20180230467
2018-08-16

Brush polymer-assisted compaction of oligonucleotides

 #627
20180216116
2018-08-02

Antisense oligomers targeting PCSK9

 #628
20180216115
2018-08-02

Compositions and methods for inhibiting expression of the PCSK9 gene

 #629
20180216113
2018-08-02

METHODS FOR REDUCING PROTEOTOXICITY

 #630
20180201929
2018-07-19

Insulin-like growth factor binding protein, acid labile subunit (IGFALS) compositions and methods of use thereof

 #631
20180195062
2018-07-12

Pharmaceutical Composition

 #632
20180171332
2018-06-21

siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis

 #633
20180169016
2018-06-21

Lipid-derived neutral nanoparticles

 #634
20180169015
2018-06-21

Lipid-derived neutral nanoparticles

 #635
20180163204
2018-06-14

Micro-RNA family that modulates extracellular matrix genes and uses thereof

 #636
20180155718
2018-06-07

RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality

 #637
20180148726
2018-05-31

RNAi inhibition of alpha-ENaC expression

 #638
20180148723
2018-05-31

Chemical modification of short small hairpin RNAs for inhibition of gene expression

 #639
20180148719
2018-05-31

Delivering CRISPR therapeutics with lipid nanoparticles

 #640
20180125985
2018-05-10

Lipids and compositions for the delivery of therapeutics

 #641
20180119151
2018-05-03

Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability

 #642
20180119147
2018-05-03

RNA amidates and thioamidates for RNAi

 #643
20180094263
2018-04-05

Oligonucleotide compounds for targeting huntingtin mRNA

 #644
20180092990
2018-04-05

Polynucleotide agents targeting hydroxyacid oxidase (glycolate oxidase, HAO1) and methods of use thereof

 #645
20180092971
2018-04-05

Lipids and compositions for the delivery of therapeutics

 #646
20180087054
2018-03-29

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

 #647
20180080024
2018-03-22

Single-stranded RNAi agents containing an internal, non-nucleic acid spacer

 #648
20180080023
2018-03-22

MIRNA MIMETICS AND THEIR USE IN TREATING SENSORY CONDITIONS

 #649
20180078625
2018-03-22

Compositions and methods for delivery of biomacromolecule agents

 #650
20180073024
2018-03-15

Chimeric double-stranded nucleic acid

 #651
20180066255
2018-03-08

Compositions and methods for inhibition of expression of protein C (PROC) genes

 #652
20180066254
2018-03-08

RNA interference mediated therapy for neurodegenerative diseases

 #653
20180064819
2018-03-08

Targeting ligands

 #654
20180064807
2018-03-08

NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

 #655
20180064749
2018-03-08

Conjugation of lipophilic albumin-binding moiety to RNA for improved carrier-free in vivo pharmacokinetics and gene silencing

 #656
20180057814
2018-03-01

Compositions and methods for inhibition of nucleic acids function

 #657
20180044676
2018-02-15

Compositions and methods for modulating TTR expression

 #658
20180043009
2018-02-15

Lipids and compositions for the delivery of therapeutics

 #659
20180042849
2018-02-15

Cochleates and methods of using the same to enhance tissue penetration of pharmacologically active agent

 #660
20180030451
2018-02-01

Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1

 #661
20180030437
2018-02-01

Acyl-amino-LNA and/or hydrocarbyl-amino-LNA oligonucleotides

 #662
20180023086
2018-01-25

Compositions and methods for inhibiting gene expression of factor XII

 #663
20180023084
2018-01-25

Disulfide-containing alkyne linking agents

 #664
20180016294
2018-01-18

Oligonucleotide compositions and methods of making the same

 #665
20180016293
2018-01-18

Oligonucleotide compositions and methods of making the same

 #666
20180010128
2018-01-11

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

 #667
20180002724
2018-01-04

Agents for improved delivery of nucleic acids to eukaryotic cells

 #668
20180002693
2018-01-04

COMPOSITIONS AND METHODS

 #669
20170369882
2017-12-28

FULLY STABILIZED ASYMMETRIC SIRNA

 #670
20170355994
2017-12-14

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

 #671
20170349901
2017-12-07

Hepatitis D virus (HDV) iRNA compositions and methods of use thereof

 #672
20170349900
2017-12-07

Hepatitis B virus (HBV) iRNA compositions and methods of use thereof

 #673
20170348432
2017-12-07

Modified polycationic polymers

 #674
20170342416
2017-11-30

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

 #675
20170340661
2017-11-30

Patatin-like phospholipase domain containing 3 (PNPLA3) iRNA compositions and methods of use thereof

 #676
20170335327
2017-11-23

Methods and compositions for preventing ischemia reperfusion injury in organs

 #677
20170327829
2017-11-16

Organic compositions to treat Beta-ENaC-related diseases

 #678
20170321213
2017-11-09

Compositions and methods for inhibiting expression of transthyretin

 #679
20170312367
2017-11-02

Branched oligonucleotides

 #680
20170306331
2017-10-26

Anti-TNF compounds

 #681
20170304446
2017-10-26

Compositions and methods for inhibition of HAO1 (Hydroxyacid Oxidase 1 (Glycolate Oxidase)) gene expression

 #682
20170298358
2017-10-19

Treatment of idiopathic pulmonary fibrosis using RNA complexes that target connective tissue growth factor

 #683
20170298086
2017-10-19

RNA interference agents for p21 gene modulation

 #684
20170283801
2017-10-05

Therapeutic compositions

 #685
20170268002
2017-09-21

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

 #686
20170260527
2017-09-14

Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof

 #687
20170260523
2017-09-14

NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY

 #688
20170260278
2017-09-14

Methods of inhibiting pathological angiogenesis with doppel-targeting molecules

 #689
20170253875
2017-09-07

Targeting ligands for therapeutic compounds

 #690
20170240890
2017-08-24

GNAQ targeted dsRNA compositions and methods for inhibiting expression

 #691
20170218376
2017-08-03

Treatment of atopic dermatitis and asthma using RNA complexes that target IL4Rα, TRPA1, or F2RL1

 #692
20170218374
2017-08-03

Treatment of angiogenesis-associated diseases using RNA complexes that target ANGPT2 and PDGFB

 #693
20170218371
2017-08-03

MicroRNA compounds and methods for modulating miR-122

 #694
20170218367
2017-08-03

Nucleic acid amphiphiles and nanostructures

 #695
20170204417
2017-07-20

dsRNA for treating viral infection

 #696
20170204415
2017-07-20

Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof

 #697
20170204408
2017-07-20

Compositions for Targeted Delivery of siRNA

 #698
20170204075
2017-07-20

Aminoalcohol lipidoids and uses thereof

 #699
20170183686
2017-06-29

Exosomal loading using hydrophobically modified oligonucleotides

 #700
20170183416
2017-06-29

Methods of inhibiting pathological angiogenesis with doppel-targeting molecules

 #701
20170182177
2017-06-29

Delivery of agents using interfering nanoparticles

 #702
20170175121
2017-06-22

SELF ASSEMBLING NUCLEIC ACID NANOSTRUCTURES

 #703
20170175112
2017-06-22

MIR-21-3P INHIBITORS IN SKIN DISORDERS

 #704
20170152512
2017-06-01

Nanoparticle type oligonucleotide structure having high efficiency and method for preparing same

 #705
20170143631
2017-05-25

LIPID FORMULATION

 #706
20170137823
2017-05-18

Inhibition of PCSK9 through RNAI

 #707
20170137821
2017-05-18

MOLECULES AND AGENTS FOR TREATING HEPATITIS B VIRUS

 #708
20170137814
2017-05-18

Organic compositions to treat APOC3-related diseases

 #709
20170130231
2017-05-11

Double-stranded oligo RNA targeted to amphiregulin and pharmaceutical composition comprising same for preventing or treating fibrosis or respiratory diseases

 #710
20170130225
2017-05-11

Modified oligonucleotides for telomerase inhibition

 #711
20170114341
2017-04-27

POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS

 #712
20170107517
2017-04-20

Double-stranded RNA conjugates and their use

 #713
20170096670
2017-04-06

DNA aptamers specific to CD200R1 and their therapeutic uses

 #714
20170067056
2017-03-09

RNA interference in dermal and fibrotic indications

 #715
20170051288
2017-02-23

Methods for treating cancer using nucleic acids targeting MDM2 or MYCN

 #716
20170051284
2017-02-23

Manipulating microRNA for the management of neurological diseases or conditions and compositions related thereto

 #717
20170051283
2017-02-23

RNA interference for the treatment of gain-of-function disorders

 #718
20170044545
2017-02-16

APTAMER FOR BONDING TO AUTOTAXIN AND INHIBITING BIOLOGICAL ACTIVITY OF AUTOTAXIN, AND USE FOR SAME

 #719
20170043024
2017-02-16

Bioactive conjugates for oligonucleotide delivery

 #720
20170037402
2017-02-09

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

 #721
20170029817
2017-02-02

Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases

 #722
20170028074
2017-02-02

MultiLigand agent for drug delivery

 #723
20170021030
2017-01-26

Asymmetric bifunctional silyl monomers and particles thereof as prodrugs and delivery vehicles for pharmaceutical, chemical and biological agents

 #724
20170009239
2017-01-12

RNA interference in skin indications

 #725
20170009232
2017-01-12

Compositions and methods for inhibition of nucleic acids function

 #726
20170007636
2017-01-12

Microbubble complexes and methods of use

 #727
20170000815
2017-01-05

LIPID FORMULATED DSRNA TARGETING THE PCSK9 GENE

 #728
20160376599
2016-12-29

RNAi inhibition of alpha-ENaC expression

 #729
20160376296
2016-12-29

Biocompatible flavonoid compounds for organelle and cell imaging

 #730
20160355808
2016-12-08

Oligonucleotide compounds for targeting huntingtin mRNA

 #731
20160354404
2016-12-08

Compositions and Methods for Inhibition of PCSK9 Genes

 #732
20160348117
2016-12-01

Compositions and methods for inhibiting expression of the PCSK9 gene

 #733
20160340679
2016-11-24

Ketohexokinase (KHK) iRNA compositions and methods of use thereof

 #734
20160333342
2016-11-17

Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes

 #735
20160319284
2016-11-03

Methods and compositions for treating cancer using peptide nucleic acid-based agents

 #736
20160312227
2016-10-27

Methods of polynucleotide preparation using multivalent cation salt compositions

 #737
20160304873
2016-10-20

Immunotherapy of cancer

 #738
20160281087
2016-09-29

Modulation of T cell signaling threshold and T cell sensitivity to antigens

 #739
20160272979
2016-09-22

Organic compositions to treat beta-ENaC-related diseases

 #740
20160272978
2016-09-22

Compositions and methods for inhibiting gene expression of factor XII

 #741
20160272971
2016-09-22

Disulfide-containing alkyne linking agents

 #742
20160264968
2016-09-15

MODIFIED iRNA AGENTS

 #743
20160264966
2016-09-15

Compositions and methods for inhibiting expression of the LECT2 gene

 #744
20160264963
2016-09-15

Compositions and Methods for Inhibiting Expression of Transthyretin

 #745
20160257955
2016-09-08

Methods for inducing cardiomyocyte proliferation

 #746
20160257954
2016-09-08

SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

 #747
20160256570
2016-09-08

Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety

 #748
20160251681
2016-09-01

Non-liposomal systems for nucleic acid delivery

 #749
20160251657
2016-09-01

MicroRNA compounds and methods for modulating miR-122

 #750
20160244765
2016-08-25

Reduced size self-delivering RNAI compounds

 #751
20160244757
2016-08-25

Compositions and methods for modulating neuronal excitability and motor behavior

 #752
20160244756
2016-08-25

Formats for organic compounds for use in RNA interference

 #753
20160244752
2016-08-25

Serpina1 siRNAs: compositions of matter and methods of treatment

 #754
20160235856
2016-08-18

Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types

 #755
20160222384
2016-08-04

Compositions for targeted delivery of siRNA

 #756
20160222381
2016-08-04

Single-stranded RNAi agents containing an internal, non-nucleic acid spacer

 #757
20160215288
2016-07-28

Organic compounds to treat hepatitis B virus

 #758
20160208265
2016-07-21

RNA interference agents for GST-PI gene modulation

 #759
20160208259
2016-07-21

Targeting microRNAs for metabolic disorders

 #760
20160208258
2016-07-21

miR-92 inhibitors and uses thereof

 #761
20160208256
2016-07-21

RNA interference agents for P21 gene modulation

 #762
20160208255
2016-07-21

RNA agents for P21 gene modulation

 #763
20160208254
2016-07-21

RNA agents for GST-Pi gene modulation

 #764
20160208245
2016-07-21

RNA/DNA nanoparticle for siRNA target-specific delivery and vehicle including the same

 #765
20160206749
2016-07-21

METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA OR A DOUBLE-STRANDED HYBRID NUCLEIC ACID TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS

 #766
20160199485
2016-07-14

Lipids and compositions for the delivery of therapeutics

 #767
20160194645
2016-07-07

Compositions and methods for inhibiting expression of mutant EGFR gene

 #768
20160194642
2016-07-07

SPHERICAL NUCLEIC ACID-BASED CONSTRUCTS AS IMMUNOREGULATORY AGENTS

 #769
20160194633
2016-07-07

Lipid formulated compositions and methods for inhibiting expression of serum amyloid A gene

 #770
20160186183
2016-06-30

Methods and compositions for treating malignant tumors associated with KRAS mutation

 #771
20160186182
2016-06-30

RNA interference compositions and methods for malignant tumors

 #772
20160186180
2016-06-30

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

 #773
20160186173
2016-06-30

C-myc antisense oligonucleotides and methods for using the same to treat cell-proliferative disorders

 #774
20160186172
2016-06-30

Compositions and methods for inhibiting hepcidin antimicrobial peptide (HAMP) or HAMP-related gene expression

 #775
20160184226
2016-06-30

Synthetic nanostructures including nucleic acids and/or other entities

 #776
20160177302
2016-06-23

MicroRNA (miRNA) and downstream targets for diagnostic and therapeutic purposes

 #777
20160152983
2016-06-02

RIG-I ligands and methods for producing them

 #778
20160151514
2016-06-02

Low density lipoprotein receptor-mediated siRNA delivery

 #779
20160145625
2016-05-26

Dnazyme for silencing the expression of EGFR

 #780
20160145622
2016-05-26

Dengue virus-specific siRNA, double helix oligo-RNA structure comprising siRNA, and composition for suppressing proliferation of dengue virus comprising RNA structure

 #781
20160145614
2016-05-26

Double-stranded agents for delivering therapeutic oligonucleotides

 #782
20160145609
2016-05-26

Micro-RNA family that modulates fibrosis and uses thereof

 #783
20160145608
2016-05-26

Micro-RNA family that modulates fibrosis and uses thereof

 #784
20160145607
2016-05-26

Micro-RNA family that modulates fibrosis and uses thereof

 #785
20160138025
2016-05-19

Oligonucleotide conjugates

 #786
20160130607
2016-05-12

Agents for improved delivery of nucleic acids to eukaryotic cells

 #787
20160130580
2016-05-12

RNA amidates and thioamidates for RNAi

 #788
20160130578
2016-05-12

Reduced size self-delivering RNAi compounds

 #789
20160122759
2016-05-05

Dosages and methods for delivering lipid formulated nucleic acid molecules

 #790
20160115482
2016-04-28

RNA interference in ocular indications

 #791
20160113957
2016-04-28

Hydrophobically modified antisense oligonucleotides comprising a triple alkyl chain

 #792
20160108398
2016-04-21

Hydrophobically modified antisense oligonucleotides comprising a ketal group

 #793
20160090596
2016-03-31

Compositions and methods for modulating apolipoprotein (a) expression

 #794
20160090595
2016-03-31

Compositions and methods for modulating apolipoprotein C-III expression

 #795
20160076040
2016-03-17

Therapeutic compositions

 #796
20160076032
2016-03-17

Compositions and methods

 #797
20160076030
2016-03-17

Compositions and methods for modulating HBV expression

 #798
20160076029
2016-03-17

siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis

 #799
20160076026
2016-03-17

DIAGNOSTIC AND THERAPEUTIC METHODS RELATING TO MICRORNA-144

 #800
20160074525
2016-03-17

NOVEL SINGLE CHEMICAL ENTITIES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES

 #801
20160030571
2016-02-04

Therapeutic agent for fibroid lung

 #802
20160024501
2016-01-28

Methods for including cardiomyocyte proliferation

 #803
20160024499
2016-01-28

Compositions and methods for inhibition of expression of protein C (PROC) genes

 #804
20160017337
2016-01-21

Compositions and Methods for Inhibiting Expression of Eg5 Gene

 #805
20160017335
2016-01-21

PCSK9 iRNA compositions and methods of use thereof

 #806
20160017330
2016-01-21

Serpinc1 iRNA compositions and methods of use thereof

 #807
20160017329
2016-01-21

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

 #808
20160010093
2016-01-14

Oligomers and oligomer conjugates

 #809
20150376624
2015-12-31

Modified oligonucleotides for telomerase inhibition

 #810
20150376621
2015-12-31

MODIFIED SMALL INTERFERING RNA MOLECULES AND METHODS OF USE

 #811
20150361427
2015-12-17

Compositions and methods for inhibiting gene expression of alpha-1 AntiTrypsin

 #812
20150352221
2015-12-10

Peptide-based in vivo siRNA delivery system

 #813
20150344879
2015-12-03

Compounds and methods for modulating gene expression

 #814
20150342982
2015-12-03

Use of Telomerase Inhibitors for the Treatment of Myeloproliferative Disorders and Myeloproliferative Neoplasms

 #815
20150337317
2015-11-26

dsRNA For Treating Viral Infection

 #816
20150337314
2015-11-26

Oligonucleotide compositions and methods of making the same

 #817
20150337305
2015-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

 #818
20150337304
2015-11-26

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

 #819
20150322438
2015-11-12

Modified oligonucleotides for telomerase inhibition

 #820
20150322437
2015-11-12

Modified oligonucleotides for telomerase inhibition

 #821
20150322432
2015-11-12

Compositions and methods for functional nucleic acid delivery

 #822
20150315584
2015-11-05

Compositions and methods for silencing apolipoprotein C-III expression

 #823
20150291958
2015-10-15

ANTI APOB ANTISENSE CONJUGATE COMPOUNDS

 #824
20150290340
2015-10-15

Short interference RNA gene delivery system for systemic circulation

 #825
20150284726
2015-10-08

RNAi inhibition of alpha-ENaC expression

 #826
20150275218
2015-10-01

Organic compositions to treat beta-ENaC-related diseases

 #827
20150275217
2015-10-01

RIG-I ligands and methods for producing them

 #828
20150275212
2015-10-01

Oligonucleotide conjugates

 #829
20150274780
2015-10-01

Conformationally-constrained kinked endosomal-disrupting peptides

 #830
20150265708
2015-09-24

Lipids and compositions for the delivery of therapeutics

 #831
20150252369
2015-09-10

METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA OR A DOUBLE-STRANDED HYBRID NUCLEIC ACID TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS

 #832
20150250898
2015-09-10

NANOCOMPOSITES FOR IMAGING AND DRUG DELIVERY

 #833
20150238517
2015-08-27

Methods and compositions for treating cancer

 #834
20150232840
2015-08-20

Methods and compositions for treating neurological disease

 #835
20150203847
2015-07-23

CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION

 #836
20150203439
2015-07-23

Aminoalcohol lipidoids and uses thereof

 #837
20150196648
2015-07-16

Methods and compositions for treating prostate cancer

 #838
20150191726
2015-07-09

Ligand-conjugated monomers

 #839
20150191722
2015-07-09

COMPOSITIONS AND METHODS FOR MODULATING APOA1 AND ABCA1 EXPRESSION

 #840
20150190525
2015-07-09

Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy

 #841
20150166992
2015-06-18

Compositions and methods for inhibition of nucleic acids function

 #842
20150165066
2015-06-18

Low density lipoprotein receptor-mediated siRNA delivery

 #843
20150159160
2015-06-11

Compositions and methods for modulating ATP2A2 expression

 #844
20150152418
2015-06-04

Methods of treating vascular inflammatory disorders

 #845
20150152414
2015-06-04

Chemical modification of short small hairpin RNAs for inhibition of gene expression

 #846
20150148530
2015-05-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

 #847
20150141348
2015-05-21

Sustained release siRNA for ocular drug delivery

 #848
20150140067
2015-05-21

Therapeutic micro RNA targets in chronic pulmonary diseases

 #849
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Compositions and methods for modulating apolipoprotein (a) expression

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2015-05-07

Compositions and methods for modulating apolipoprotein C-III expression

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20150126718
2015-05-07

Conjugated antisense compounds and their use

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20150111948
2015-04-23

RNA-interference-inducing nucleic acid molecule able to penetrate into cells, and use therefor

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20150105449
2015-04-16

MicroRNA compounds and methods for modulating miR-122

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2015-03-26

Lipid-derived neutral nanoparticles

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2015-03-19

Compositions and methods related to protein displacement therapy for myotonic distrophy

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2015-02-05

Targeting MicroRNAs for metabolic disorders

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2015-01-15

Oligomer-conjugate complexes and their use

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20150011608
2015-01-08

iRNA Agents Targeting VEGF

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20150005364
2015-01-01

High-efficiency nanoparticle-type double-helical oligo-RNA structure and method for preparing same

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20150004186
2015-01-01

Modulation of T cell signaling threshold and T cell sensitivity to antigens

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20140370597
2014-12-18

RNA interference for the treatment of gain-of-function disorders

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20140364482
2014-12-11

Reduced size self-delivering RNAi compounds

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20140350232
2014-11-27

siRNA conjugate and preparation method thereof

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2014-11-27

MicroRNA compounds and methods for modulating miR-122

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Compositions and methods for inhibiting expression of the PCSK9 gene

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2014-11-20

Conjugated antisense compounds and their use

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2014-11-20

Compositions and methods for inhibiting expression of factor VII gene

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2014-11-13

Oligomeric compounds and compositions for use in modulation of small non-coding RNAs

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2014-11-06

Pharmaceutical composition comprising anti-miRNA antisense oligonucleotides

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20140329882
2014-11-06

Oligomeric compounds and compositions for use in modulation of small non-coding RNAS

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2014-11-06

METHOD FOR IMPROVING THE SUCCESS RATE OF HEMATOPOIETIC STEM CELL TRANSPLANTS

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2014-10-23

RNA interference in skin indications

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2014-10-16

Therapeutic compositions

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20140302603
2014-10-09

Chimeric double-stranded nucleic acid

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2014-10-02

Synthetic nanostructures including nucleic acids and/or other entities

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20140249205
2014-09-04

Activation of quiescent stem cells

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2014-08-21

RNA aptamer specifically binding to carcinoembryonic antigen and use thereof

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20140221466
2014-08-07

MicroRNA inhibitors

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20140194493
2014-07-10

Compositions and methods for inhibiting expression of transthyretin

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20140193366
2014-07-10

Modulators of miR-323-3p for the prevention or treatment of rheumatoid arthritis

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20140179768
2014-06-26

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

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20140179759
2014-06-26

Lipid formulated compositions and methods for inhibiting expression of serum amyloid A gene

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20140155813
2014-06-05

Therapeutic muscular dystrophy drug having bubble liposome loaded with morpholino as active ingredient

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20140142162
2014-05-22

Compositions and methods for inhibition of expression of protein C (PROC) genes

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20140134233
2014-05-15

Suppressors of CpG oligonucleotides and methods of use

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20140121264
2014-05-01

Microrna (miRNA) and downstream targets for diagnostic and therapeutic purposes

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20140121261
2014-05-01

C-myc antisense oligonucleotides and methods for using the same to treat cell-proliferative disorders

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20140113957
2014-04-24

Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes

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20140113950
2014-04-24

RNA interference in dermal and fibrotic indications

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20140100266
2014-04-10

Cancer treatment by combining DNA molecules mimicking double strand breaks with hyperthermia

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20140073683
2014-03-13

Modified small interfering RNA molecules and methods of use

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20140057965
2014-02-27

dsRNA for treating viral infection

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20140057963
2014-02-27

Oligomeric compounds and compositions for use in modulation of small non-coding RNAS

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20140045922
2014-02-13

RNAi modulation of ApoB and uses thereof

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2013-11-28

Serpinc1 iRNA compositions and methods of use thereof

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20130317080
2013-11-28

Modified iRNA agents

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20130281658
2013-10-24

Peptide-based in vivo siRNA delivery system

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20130274311
2013-10-17

Compositions and methods for inhibiting expression of Eg5 gene

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20130274310
2013-10-17

RNAi modulation of SCAP and therapeutic uses thereof

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2013-10-03

Micro-RNA family that modulates fibrosis and uses thereof