ClassID:

109200

C12N2310/3521 - page 3 - CPC Classification

Classification description:

Structure or type of the nucleic acid; Chemical structure; Nature of the modification linked to the nucleic acid via a carbon atom Methyl

Recent Application in this class:
#601
20090239933
2009-09-24

HEPATITIS C ANTIVIRALS

#602
20090239931
2009-09-24

RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#603
20090228998
2009-09-10

Induction of exon skipping in eukaryotic cells

#604
20090215864
2009-08-27

Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer

#605
20090209626
2009-08-20

Duplex oligonucleotides with enhanced functionality in gene regulation

#606
20090209478
2009-08-20

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE HAMP GENE

#607
20090203893
2009-08-13

ANTISENSE COMPOUNDS HAVING ENHANCED ANTI-MICRORNA ACTIVITY

#608
20090203890
2009-08-13

HEPATITIS C ANTIVIRALS

#609
20090203766
2009-08-13

vWF aptamer formulations and methods for use

#610
20090202493
2009-08-13

MIR-150 FOR THE TREATMENT OF BLOOD DISORDERS

#611
20090198047
2009-08-06

2'-Modified Oligonucleotides

#612
20090197332
2009-08-06

Modified short interfering RNA

#613
20090192110
2009-07-30

RNA antagonist compounds for the modulation of PIK3CA expression

#614
20090192106
2009-07-30

Modulation of eIF4E expression

#615
20090192105
2009-07-30

RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA)

#616
20090192104
2009-07-30

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#617
20090186846
2009-07-23

Methods to reprogram splice site selection in pre-messenger RNAs

#618
20090186845
2009-07-23

Interfering RNA molecules

#619
20090186843
2009-07-23

RNA sequence-specific mediators of RNA interference

#620
20090182136
2009-07-16

Small internally segmented interfering RNA

#621
20090176729
2009-07-09

METHOD OF TREATING NEURODEGENERATIVE DISEASE

#622
20090176723
2009-07-09

Methods and compositions involving miRNA and miRNA inhibitor molecules

#623
20090176710
2009-07-09

Complex for transferring an anionic substance into a cell

#624
20090170219
2009-07-02

Nucleic acid capable of binding to immunoglobulin G and use thereof

#625
20090170197
2009-07-02

Nucleic Acid-Mediated Treatment of Diseases or Conditions Related to Levels of Vascular Endothelial Growth Factor Receptor (VEGF-R)

#626
20090162365
2009-06-25

Novel siRNAS and methods of use thereof

#627
20090156541
2009-06-18

DBAIT and uses thereof

#628
20090156539
2009-06-18

Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field

#629
20090156533
2009-06-18

RNA INTERFERENCE MEDIATED INHIBITION OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#630
20090156529
2009-06-18

RNAi inhibition of alpha-ENaC expression

#631
20090156528
2009-06-18

RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)

#632
20090156527
2009-06-18

Antiviral oligonucleotides targeting viral families

#633
20090156524
2009-06-18

Novel siRNAS and methods of use thereof

#634
20090155174
2009-06-18

RNA Interference Mediating Small RNA Molecules

#635
20090149643
2009-06-11

Aptamers to von Willebrand factor and their use as thrombotic disease therapeutics

#636
20090149408
2009-06-11

RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)

#637
20090149407
2009-06-11

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#638
20090143325
2009-06-04

RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)

#639
20090143324
2009-06-04

RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)

#640
20090143323
2009-06-04

Compositions and methods for inhibiting expression of a gene from the Ebola

#641
20090143322
2009-06-04

Cell transfecting formulations of small interfering RNA related compositions and methods of making and use

#642
20090143319
2009-06-04

Transcription factor decoy

#643
20090137513
2009-05-28

RNA Interference Mediated Inhibition of Acetyl-CoA-Carboxylase Gene Expression Using Short Interfering Nucleic Acid (siNA)

#644
20090137512
2009-05-28

RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)

#645
20090137511
2009-05-28

RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (SINA)

#646
20090137510
2009-05-28

RNA INTERFERENCE MEDIATED INHIBITION OF NF-KAPPA B/ REL-A GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#647
20090137509
2009-05-28

RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATION CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#648
20090137508
2009-05-28

RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)

#649
20090137507
2009-05-28

RNA INTERFERENCE MEDIATED INHIBITION OF ANGIOPOIETIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#650
20090137500
2009-05-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)

#651
20090136957
2009-05-28

Methods and compositions for regulating cell cycle progression via the miR-106B family

#652
20090131360
2009-05-21

Tripartite RNAi constructs

#653
20090105174
2009-04-23

NUCLEIC ACIDS HYBRIDIZABLE TO MICRO RNA AND PRECURSORS THEREOF

#654
20090099123
2009-04-16

Antisense microRNA and uses therefor

#655
20090099121
2009-04-16

RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)

#656
20090099120
2009-04-16

RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)

#657
20090099119
2009-04-16

RNA INTERFERENCE MEDIATED INHIBITION OF RAS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#658
20090099118
2009-04-16

RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA)

#659
20090099117
2009-04-16

RNA INTERFERENCE MEDIATED INHIBITION OF MYOSTATIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#660
20090099116
2009-04-16

RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)

#661
20090099115
2009-04-16

RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA)

#662
20090099110
2009-04-16

Antiviral oligonucleotides

#663
20090093439
2009-04-09

RNA INTERFERENCE MEDIATED INHIBITION OF CHROMOSOME TRANSLOCATION GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

#664
20090093438
2009-04-09

RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA)

#665
20090093436
2009-04-09

RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)

#666
20090093435
2009-04-09

RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acid (siNA)

#667
20090093426
2009-04-09

RNAi modulation of SCAP and therapeutics uses thereof

#668
20090093059
2009-04-09

Compositions and methods to stack multiple nucleotide sequences of interest in the genome of a plant

#669
20090088721
2009-04-02

Enhanced retinal delivery of a nucleic acid through iontophoresis

#670
20090083873
2009-03-26

Sequence-specific inhibition of small RNA function

#671
20090082555
2009-03-26

Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics

#672
20090076246
2009-03-19

Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure

#673
20090075342
2009-03-19

Metabolic profile directed aptamer medicinal chemistry

#674
20090062225
2009-03-05

Compositions and methods for inhibiting expression of a gene from the JC virus

#675
20090053138
2009-02-26

Stabilized Aptamers to Platelet Derived Growth Factor and their Use as Oncology Therapeutics

#676
20090048435
2009-02-19

Oligonucleotide modulation of cell adhesion

#677
20090042827
2009-02-12

Antiviral oligonucleotides targeting HBV

#678
20090041809
2009-02-12

DOUBLE-STRANDED LOCKED NUCLEIC ACID COMPOSITIONS

#679
20090029934
2009-01-29

RNA interference in respiratory epithelial cells

#680
20090023676
2009-01-22

RNA Interference Mediated Inhibition of MAP Kinase Gene Expression or Expression of Genes Involved in MAP Kinase Pathway Using Short Interfering Nucleic Acid (SiNA)

#681
20090023675
2009-01-22

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#682
20090018097
2009-01-15

MODIFICATION OF DOUBLE-STRANDED RIBONUCLEIC ACID MOLECULES

#683
20090018093
2009-01-15

Nucleic Acid Ligands Specific to Immunoglobuline E and Their Use as Atopic Disease Therapeutics

#684
20090005336
2009-01-01

Use of the microRNA miR-1 for the treatment, prevention, and diagnosis of cardiac conditions

#685
20080306014
2008-12-11

Agents, compositions and methods for treating pathologies in which regulating an ache-associated biological pathway is beneficial

#686
20080293655
2008-11-27

Tandem siRNAS

#687
20080293136
2008-11-27

NUCLEIC ACID COMPOUNDS FOR INHIBITING AKT GENE EXPRESSION AND USES THEREOF

#688
20080292648
2008-11-27

Synthetic agonists of TLR9

#689
20080292619
2008-11-27

Pharmaceutical Composition Containing Meltrin Antagonist

#690
20080287386
2008-11-20

Oligoribonucleotides and methods of use thereof for treatment of fibrotic conditions and other diseases

#691
20080287379
2008-11-20

Oligonucleotide complex compositions and methods of use as gene alteration tools

#692
20080274116
2008-11-06

Lipids, lipid complexes and use thereof

#693
20080269147
2008-10-30

RNA interference mediating small RNA molecules

#694
20080261904
2008-10-23

Chimeric Gapped Oligomeric Compounds

#695
20080254443
2008-10-16

Norovirus detection, methods and compositions therefor

#696
20080249294
2008-10-09

RNA Interference Mediated Inhibition of Gene Expression Using Short Interfering Nucleic Acid (siNA)

#697
20080249046
2008-10-09

Modified siRNA molecules and uses thereof

#698
20080242851
2008-10-02

Modified polynucleotides for reducing off-target effects in RNA interference

#699
20080241825
2008-10-02

Materials and methods for treatment of cancer

#700
20080234220
2008-09-25

Methods and compositions for reducing viral genome amounts in a target cell

#701
20080234214
2008-09-25

Oligonucleotide-containing pharmacological compositions and their use

#702
20080221055
2008-09-11

Compositions and methods for inhibiting expression of Huntingtin gene

#703
20080209595
2008-08-28

Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant

#704
20080209581
2008-08-28

Induction of exon skipping in eukaryotic cells

#705
20080207883
2008-08-28

Platelet derived growth factor (PDGF) nucleic acid ligand complexes

#706
20080200416
2008-08-21

Modulation of T cell signaling threshold and T cell sensitivity to antigens

#707
20080199960
2008-08-21

Methods for the Delivery of Oligomeric Compounds

#708
20080188430
2008-08-07

RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)

#709
20080188429
2008-08-07

Synthetic siRNA compounds and methods for the downregulation of gene expression

#710
20080176766
2008-07-24

Methods and compositions involving miRNA and miRNA inhibitor molecules

#711
20080171716
2008-07-17

NUCLEIC ACID MODULATION OF TOLL-LIKE RECEPTOR-MEDIATED IMMUNE STIMULATION

#712
20080171715
2008-07-17

Methods and compositions involving miRNA and miRNA inhibitor molecules

#713
20080171712
2008-07-17

Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8

#714
20080167257
2008-07-10

Oligonucleotide-containing pharmacological compositions and their use

#715
20080161257
2008-07-03

Oligonucleotide-containing pharmacological compositions and their use

#716
20080153769
2008-06-26

Modulators of coagulation factors

#717
20080146788
2008-06-19

Positionally modified siRNA constructs

#718
20080132461
2008-06-05

RNA sequence-specific mediators of RNA interference

#719
20080125383
2008-05-29

Modulators of coagulation factors with enhanced stability

#720
20080119427
2008-05-22

Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation

#721
20080119426
2008-05-22

Compositions and methods for the treatment of muscle wasting

#722
20080113930
2008-05-15

Compositions and methods for inhibiting expression of the PCSK9 gene

#723
20080108801
2008-05-08

Lipophilic conjugated iRNA agents

#724
20080108584
2008-05-08

Compositions and methods for inhibiting expression of IKK-B gene

#725
20080085999
2008-04-10

MODULATION OF GENE EXPRESSION USING DNA-RNA HYBRIDS

#726
20080085869
2008-04-10

Duplex oligonucleotide complexes and methods for gene silencing by RNA interference

#727
20080069827
2008-03-20

miRNA of HSV-LAT and uses thereof

#728
20080064650
2008-03-13

Therapeutic uses of inhibitors of RTP801L

#729
20080051363
2008-02-28

G-rich polynucleotides as a novel therapeutic for the treatment of huntington's disease

#730
20080051339
2008-02-28

Modulators of pharmacological agents

#731
20080050744
2008-02-28

Methods and compositions involving miRNA and miRNA inhibitor molecules

#732
20080039618
2008-02-14

POLYCYCLIC SUGAR SURROGATE-CONTAINING OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN GENE MODULATION

#733
20080039415
2008-02-14

RETROGRADE TRANSPORT OF SIRNA AND THERAPEUTIC USES TO TREAT NEUROLOGIC DISORDERS

#734
20080033156
2008-02-07

Polycationic compositions for cellular delivery of polynucleotides

#735
20080032945
2008-02-07

2'-MODIFIED OLIGONUCLEOTIDES

#736
20080032942
2008-02-07

RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

#737
20080027214
2008-01-31

Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes

#738
20080015162
2008-01-17

Short antisense compounds with gapmer configuration

#739
20080015161
2008-01-17

RNAi modulation of TGF-beta and therapeutic uses thereof

#740
20080009456
2008-01-10

Antisense modulation of kinesin-like 1 expression

#741
20070298025
2007-12-27

Pharmaceutical Compositions and Methods for Reducing Body Fat

#742
20070293657
2007-12-20

COMPLEXES AND METHODS OF FORMING COMPLEXES OF RIBONUCLEIC ACIDS AND PEPTIDES

#743
20070293452
2007-12-20

Agents, compositions and methods for treating pathologies in which regulating an ache-associated biological pathway is beneficial

#744
20070292875
2007-12-20

Human RNase H1 oligonucleotide compositions thereof

#745
20070287179
2007-12-13

Anti-microRNA oligonucleotide molecules

#746
20070281899
2007-12-06

Compositions and methods for inhibiting expression of Eg5 gene

#747
20070274936
2007-11-29

Oligonucleotide and the use thereof for modulating an isoform C beta-1 protein-kinase in the form of a skin depigmentation agent

#748
20070270368
2007-11-22

Compositions and methods for modulation of Mcl-1 expression

#749
20070270366
2007-11-22

DOUBLE STRANDED NUCLEIC ACID MOLECULES TARGETED TO IL-4 RECEPTOR ALPHA

#750
20070270363
2007-11-22

Modulation of telomere length by oligonucleotides having a G-core sequence

#751
20070270360
2007-11-22

Rna Interference Mediated Inhibition of Severe Acute Respiratory Syndrome (Sars) Gene Expression Using Short Interfering Nucleic Acid

#752
20070269889
2007-11-22

Stabilized siRNAs as transfection controls and silencing reagents

#753
20070254362
2007-11-01

COMPOSITIONS AND METHODS EMPLOYING UNIVERSAL-BINDING NUCLEOTIDES FOR TARGETING MULTIPLE GENE VARIANTS WITH A SINGLE siRNA DUPLEX

#754
20070249551
2007-10-25

Compositions and methods for non-parenteral delivery of oligonucleotides

#755
20070249549
2007-10-25

Compounds and Methods for Rna Interference of the P65 Subunit of Nf-Kappa-B

#756
20070249538
2007-10-25

Soluble TNF receptors and their use in treatment of disease

#757
20070248535
2007-10-25

Methods to treat or prevent hormone-resistant prostate cancer using siRNA specific for protocadherin-PC, or other inhibitors of protocadherin-PC expression or activity

#758
20070218122
2007-09-20

siRNA silencing of influenza virus gene expression

#759
20070213292
2007-09-13

Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof

#760
20070198203
2007-08-23

Data correction apparatus, data correction method, magnetic resonance imaging apparatus and X-ray CT apparatus

#761
20070185049
2007-08-09

RNA interference mediated inhibition of histone deacetylase (HDAC) gene expression using short interfering nucleic acid (siNA)

#762
20070185047
2007-08-09

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#763
20070185046
2007-08-09

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#764
20070185043
2007-08-09

Rna interference mediated inhibition of nogo and nogo receptor gene expression using short interfering nucleic acid (sina)

#765
20070179109
2007-08-02

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#766
20070179108
2007-08-02

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#767
20070179107
2007-08-02

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#768
20070179106
2007-08-02

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#769
20070179100
2007-08-02

Protected monomers

#770
20070178064
2007-08-02

Antisense IAP nucleobase oligomers and uses thereof

#771
20070173476
2007-07-26

MODIFIED POLYNUCLEOTIDES FOR USE IN RNA INTERFERENCE

#772
20070173475
2007-07-26

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#773
20070173474
2007-07-26

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#774
20070172948
2007-07-26

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#775
20070167393
2007-07-19

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#776
20070167392
2007-07-19

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#777
20070167391
2007-07-19

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#778
20070167390
2007-07-19

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#779
20070167385
2007-07-19

Antisense oligonucleotides (ODN) against Smad7 and uses in medical field thereof

#780
20070167384
2007-07-19

Modified polynucleotides for use in rna interference

#781
20070166734
2007-07-19

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#782
20070161596
2007-07-12

RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA)

#783
20070161595
2007-07-12

Method of treating neurodegenerative disease

#784
20070161589
2007-07-12

Antisense modulation of CD40 expression

#785
20070155686
2007-07-05

RNAi modulation of HIF-1 and therapeutic uses thereof

#786
20070142316
2007-06-21

Antisense IAP oligonucleotides and uses thereof

#787
20070135371
2007-06-14

Antisense IAP nucleobase oligomers and uses thereof

#788
20070123484
2007-05-31

DOUBLE STRAND COMPOSITIONS COMPRISING DIFFERENTIALLY MODIFIED STRANDS FOR USE IN GENE MODULATION

#789
20070123482
2007-05-31

Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof

#790
20070123481
2007-05-31

Antisense IAP oligonucleotides and uses thereof

#791
20070123480
2007-05-31

Oligonucleotides targeting prion diseases

#792
20070117112
2007-05-24

Materials and methods for the generation of fully 2′-modified nucleic acid transcripts

#793
20070111963
2007-05-17

Modulation of gene expression by oligomers targeted to chromosomal DNA

#794
20070111961
2007-05-17

Dbait and uses thereof

#795
20070111228
2007-05-17

RNA interference

#796
20070105809
2007-05-10

Modulators of coagulation factors with enhanced stability

#797
20070105808
2007-05-10

Inhibition of histone deacetylase

#798
20070105807
2007-05-10

Splice switch oligomers for TNF superfamily receptors and their use in treatment of disease

#799
20070105806
2007-05-10

Compositions and methods for inhibiting expression of Nav1.8 gene

#800
20070105805
2007-05-10

G-rich polynucleotides for the treatment of Huntington's Disease

#801
20070099860
2007-05-03

Compositions and methods for inhibiting expression of Huntingtin gene

#802
20070093445
2007-04-26

RNA interference mediating small RNA molecules

#803
20070093437
2007-04-26

Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina)

#804
20070072198
2007-03-29

Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes

#805
20070066551
2007-03-22

Aptamer medicinal chemistry

#806
20070066550
2007-03-22

Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics

#807
20070066549
2007-03-22

Modulation of eIF4E expression

#808
20070059739
2007-03-15

Pure miRNA Sample Preparation Method

#809
20070058811
2007-03-15

Method and apparatus to facilitate transmission of an encrypted rolling code

#810
20070049544
2007-03-01

Antisense IAP nucleobase oligomers and uses thereof

#811
20070049543
2007-03-01

RNA interference mediated inhibition of 11 beta-hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) gene expression using short interfering nucleic acid siNA

#812
20070048248
2007-03-01

Aptamer therapeutics useful in the treatment of complement-related disorders

#813
20070044161
2007-02-22

RNAi modulation of the Rho-A gene in research models

#814
20070042985
2007-02-22

Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field

#815
20070042984
2007-02-22

iRNA agents targeted to the Rho-A gene

#816
20070042029
2007-02-22

Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)

#817
20070032445
2007-02-08

Antisense IAP nucleobase oligomers and uses thereof

#818
20070032441
2007-02-08

Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina)

#819
20070027097
2007-02-01

Small interfering RNA with improved activity

#820
20070026394
2007-02-01

Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies

#821
20070021327
2007-01-25

Methods and compositions for treatment of tumors using nucleic acid ligands to platelet-derived growth factor

#822
20070015723
2007-01-18

Antiviral oligonucleotides having a conserved G4 core sequence

#823
20070010473
2007-01-11

Nucleic acid ligands to integrins

#824
20070009907
2007-01-11

Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics

#825
20070004667
2007-01-04

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#826
20070004665
2007-01-04

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#827
20070004664
2007-01-04

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#828
20070004663
2007-01-04

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#829
20070003963
2007-01-04

RNA sequence-specific mediators of RNA interference

#830
20070003962
2007-01-04

RNA sequence-specific mediators of RNA interference

#831
20070003961
2007-01-04

RNA sequence-specific mediators of RNA interference

#832
20070003960
2007-01-04

RNA sequence-specific mediators of RNA interference

#833
20060293272
2006-12-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#834
20060293271
2006-12-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#835
20060293270
2006-12-28

Methods and compositions for treating ocular disorders

#836
20060293267
2006-12-28

Dual functional oligonucleotides for use as anti-viral agents

#837
20060292691
2006-12-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#838
20060287266
2006-12-21

RNA interference mediated ihibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#839
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2006-12-14

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#840
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2006-12-07

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#841
20060275903
2006-12-07

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#842
20060264395
2006-11-23

Modulation of apolipoprotein c-III expression

#843
20060264369
2006-11-23

Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics

#844
20060252723
2006-11-09

Combined therapy utilizing reduction of DNA methyltransferase expression and/or activity and interferon

#845
20060247429
2006-11-02

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#846
20060247428
2006-11-02

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#847
20060247194
2006-11-02

Rna interference mediated treatment of alzheimer's disease using short interfering nucleic acid (sina)

#848
20060246123
2006-11-02

Oligonucleotide mimetics

#849
20060241075
2006-10-26

RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)

#850
20060223990
2006-10-05

Synthesis, deprotection, analysis & purification of RNA & ribozymes

#851
20060223777
2006-10-05

Highly functional short hairpin RNA

#852
20060217337
2006-09-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#853
20060217336
2006-09-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#854
20060217335
2006-09-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#855
20060217334
2006-09-28

RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)

#856
20060217331
2006-09-28

Chemically modified double stranded nucleic acid molecules that mediate RNA interference

#857
20060217329
2006-09-28

Therapeutic uses of inhibitors of RTP801

#858
20060216317
2006-09-28

Delivery of polynucleotide agents to the central nervous system

#859
20060211640
2006-09-21

Antisense modulation of farnesoid X receptor expression

#860
20060193821
2006-08-31

Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics

#861
20060183702
2006-08-17

Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics

#862
20060178333
2006-08-10

Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof

#863
20060178326
2006-08-10

Ribozyme therapy for the treatment of proliferative skin and eye diseases

#864
20060172962
2006-08-03

Modification of MyD88 splicing using modified oligonucleotides

#865
20060166909
2006-07-27

Oligonucleotide inhibitors of MBD2/DNA demethylase and uses thereof

#866
20060160759
2006-07-20

Influenza therapeutic

#867
20060160757
2006-07-20

RNA interference mediated inhibition hairless of (HR) gene expression using short interfering nucleic acid (siNA)

#868
20060154271
2006-07-13

Enzymatic nucleic acid treatment of diseases or conditions related to levels of IKK-gamma and PKR

#869
20060148743
2006-07-06

RNA interference mediated inhibition of histone deacetylase (HDAC) gene expression using short interfering nucleic acid (siNA)

#870
20060147952
2006-07-06

Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure

#871
20060142236
2006-06-29

Antisense oligonucleotide modulation of raf gene expression

#872
20060142225
2006-06-29

RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)

#873
20060142224
2006-06-29

Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes

#874
20060135458
2006-06-22

Antiviral oligonucleotides

#875
20060135454
2006-06-22

Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes

#876
20060127891
2006-06-15

RNA interference mediated inhibition of MAP kinase gene expression or expression of genes involved in MAP kinase pathway using short interfering nucleic acid (siNA)

#877
20060122136
2006-06-08

Effective and stable DNA enzymes

#878
20060115461
2006-06-01

Apparatus and system having dry gene silencing compositions

#879
20060105980
2006-05-18

Aptamer therapeutics useful in the treatment of complement-related disorders

#880
20060105979
2006-05-18

Synergistic inhibition of VEGF and modulation of the immune response

#881
20060105976
2006-05-18

RNAi modulation of ApoB and uses thereof

#882
20060105378
2006-05-18

Tenascin-C nucleic acid ligands

#883
20060099616
2006-05-11

Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure

#884
20060094678
2006-05-04

Nuclease resistant double-stranded ribonucleic acid

#885
20060084620
2006-04-20

RNA interference in respiratory epitheial cells

#886
20060084094
2006-04-20

Conjugates for use in hepatocyte free uptake assays

#887
20060058253
2006-03-16

Methods to reprogram splice site selection in pre-messenger rnas

#888
20060040881
2006-02-23

Modulators of coagulation factors

#889
20060031946
2006-02-09

Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis

#890
20060030535
2006-02-09

Controlled modulation of the pharmacokinetics and biodistribution of aptamer therapeutics

#891
20060025374
2006-02-02

Oligoribonucleotide derivatives for specific inhibition of gene expression

#892
20060025361
2006-02-02

RNA interference mediated inhibition of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)

#893
20060019917
2006-01-26

RNA interference mediated inhibition of stromal cell-derived factor-1 (SDF-1) gene expression using short interfering nucleic acid (siNA)

#894
20060019913
2006-01-26

RNA interference mediated inhibtion of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)

#895
20060019912
2006-01-26

Cell transfecting formulations of small interfering RNA related compositions and methods of making and use

#896
20060018871
2006-01-26

Aptamer therapeutics useful in the treatment of complement-related disorders

#897
20060003957
2006-01-05

RNA virus expression and replication, methods and uses therefor

#898
20050288245
2005-12-29

Methods and compositions for reducing viral genome amounts in a target cell

#899
20050288242
2005-12-29

RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)

#900
20050282188
2005-12-22

RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)