ClassID:

109554

C12N2521/00 - CPC Classification

Classification description:

Culture process characterised by the use of hydrostatic pressure, flow or shear forces

Sub-classes:
Recent Application in this class:
#1
20260137835
2026-05-21

DECELLULARIZED CELL AGGREGATE AND PRODUCTION METHOD THEREFOR

#2
20260109945
2026-04-23

ANIMAL CELL GROWTH PROMOTER, MEDIUM FOR CULTURING ANIMAL CELLS, AND DEVICE FOR CULTURING ANIMAL CELLS

#3
20260015579
2026-01-15

ARTIFICIAL UTERINE PLATFORM AND APPLICATIONS THEREOF

#4
20260009001
2026-01-08

SYSTEMS AND METHODS FOR APPLYING MECHANICAL FORCE TO LIVING CELLS TO GENERATE A PHENOTYPIC RESPONSE

#5
20250388670
2025-12-25

CONTINUOUS MANUFACTURING PROCESS FOR BISPECIFIC ANTIBODY PRODUCTS

#6
20250241963
2025-07-31

PRODUCTION OF ENHANCED STEM CELL-BASED EXOSOMES AND USES IN SCAR TISSUE PREVENTION AND TREATMENT

#7
20250223624
2025-07-10

PRODUCTION METHOD FOR PRODUCT

#8
20250207098
2025-06-26

METHOD FOR CULTIVATING MESENCHYMAL STEM CELL

#9
20250073272
2025-03-06

PRODUCTION OF ENHANCED STEM CELL-BASED EXOSOMES AND USES IN SCAR TISSUE PREVENTION AND TREATMENT

#10
20250066723
2025-02-27

METHOD FOR THE GENERATION OF OUTER RADIAL GLIAL (ORG) CELLS

#11
20240409894
2024-12-12

METHOD FOR PRODUCING HIGH-DENSITY CULTURE CELLS

#12
20240279591
2024-08-22

COMPOSITIONS COMPRISING SPHERICAL PARTICLES AND USES OF SAME

#13
20240093136
2024-03-21

CONTROLLING PRESSURE

#14
20240066069
2024-02-29

DRIED CELL SECRETOME-BASED THERAPEUTIC AGENT FOR OSTEOARTHRITIS TREATMENT

#15
20240034998
2024-02-01

A METHOD OF PRODUCING A CARDIOMYOCYTE SPHEROID

#16
20240018475
2024-01-18

Expanding Cells In A Bioreactor

#17
20240000849
2024-01-04

MICROFLUIDIC DEVICE FOR ISOLATING COMPONENTS OF BODILY FLUIDS

#18
20230372460
2023-11-23

METHODS OF TREATING CANCER AND MONITORING ANTI-CANCER IMMUNITY

#19
20230348860
2023-11-02

Systems and methods for producing injectable enhanced stem cell exosomes, improved exosomes and methods of use

#20
20230347344
2023-11-02

COMBINATION OF PHARMACOLOGICAL AND MICROFLUIDIC FEATURES FOR IMPROVED PLATELETS PRODUCTION

#21
20230341378
2023-10-26

COMPOSITIONS AND METHODS OF CELL ATTACHMENT

#22
20230332105
2023-10-19

Expanding Cells In A Bioreactor

#23
20230091038
2023-03-23

SCALING TISSUE PRODUCTION THROUGH IMPROVED CONTROL OF MASS TRANSFER

#24
20230022203
2023-01-26

Controlling pressure

#25
20220403312
2022-12-22

Pressure manifold and culture module

#26
20220298487
2022-09-22

IN VITRO MODEL FOR A TUMOR MICROENVIRONMENT

#27
20220280562
2022-09-08

METHOD FOR OBTAINING GLOBALLY ACTIVATED MONOCYTES

#28
20220265900
2022-08-25

NEOCARTILAGE CONSTRUCTS USING UNIVERSAL CELLS

#29
20220259556
2022-08-18

METHOD FOR OBTAINING IMMUNO-SUPPRESSIVE DENDRITIC CELLS

#30
20220195364
2022-06-23

DELIVERY OF MATERIALS TO ANUCLEATE CELLS

#31
20220193301
2022-06-23

CELL SUSPENSION AND USE THEREOF

#32
20220119747
2022-04-21

Microfluid device and three-dimensional microculture method for cell

#33
20220112462
2022-04-14

METHOD FOR OBTAINING IMMUNO-STIMULATORY DENDRITIC CELLS

#34
20220010262
2022-01-13

Method For Dissociation Of Cells

#35
20210395693
2021-12-23

METHOD AND APPARATUS FOR MESENCHYMAL STEM CELLS ISOLATION AND PURIFICATION

#36
20210395678
2021-12-23

ANIMAL CELL GROWTH PROMOTER, CULTURE MEDIUM FOR ANIMAL CELL CULTURE, AND ANIMAL CELL CULTURE APPARATUS

#37
20210354143
2021-11-18

SYSTEMS AND METHODS FOR CLASSIFYING T CELL ACTIVATION STATE

#38
20210261922
2021-08-26

Method of differentiating primordial germ cell into primordial follicle in vitro

#39
20210180024
2021-06-17

Systems and methods for producing injectable enhanced stem cell exosomes, improved exosomes and methods of use

#40
20210179992
2021-06-17

Controlling pressure

#41
20210163872
2021-06-03

Cell Reprogramming Therapy

#42
20210163592
2021-06-03

Continuous manufacturing process for bispecific antibody products

#43
20210087512
2021-03-25

CELL CULTURE SYSTEM AND CELL CULTURE METHOD

#44
20210062222
2021-03-04

Apparatuses and methods using nanostraws to deliver biologically relevant cargo into non-adherent cells

#45
20210048379
2021-02-18

Method of purifying tumor cells using shear stress

#46
20210032589
2021-02-04

METHODS AND DEVICES FOR THE ISOLATION OF SUBCELLULAR COMPONENTS

#47
20200407684
2020-12-31

Method of selectively differentiating undifferentiated macrophage into M1 macrophage

#48
20200370016
2020-11-26

METHODS OF GENERATING ENUCLEATED ERYTHROID CELLS

#49
20200261620
2020-08-20

Methods and compositions for repair of cartilage using an in vivo bioreactor

#50
20200255781
2020-08-13

Systems and methods for biomimetic fluid processing

#51
20200248147
2020-08-06

Methods of enhancing development of renal organoids and methods of using the same

#52
20200208115
2020-07-02

Adaptation of hollow-fiber-based cell culture technology for the manufacturing of (1) neo-islets, employed for the treatment of type 1 and type 2 diabetes mellitus, and (2) the generation of exosomes from various cell types, used in the treatment of different organ injuries and diseases

#53
20200190455
2020-06-18

Pressure Manifold and Culture Module

#54
20200121724
2020-04-23

Compositions and methods for glaucoma

#55
20200115681
2020-04-16

Megakaryocytic particles and microparticles for in vivo hematopoietic cell and gene therapies

#56
20200093962
2020-03-26

SYSTEMS FOR CARTILAGE REPAIR

#57
20200093952
2020-03-26

CELL SUSPENSION AND USE THEREOF

#58
20200093951
2020-03-26

CELL SUSPENSION AND USE THEREOF

#59
20200086005
2020-03-19

NEOCARTILAGE CONSTRUCTS USING UNIVERSAL CELLS

#60
20200071738
2020-03-05

Increasing ornithine accumulation to increase high mannose glycoform content of recombinant proteins

#61
20200010809
2020-01-09

In vitro model for a tumor microenvironment

#62
20190270962
2019-09-05

3D micro fabrication and screening

#63
20190169557
2019-06-06

Perfusion manifold assembly

#64
20190127683
2019-05-02

Systems and methods for growing cell cultures

#65
20190119629
2019-04-25

Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

#66
20190112566
2019-04-18

Pressure manifold and culture module

#67
20190093082
2019-03-28

Method of Differentiating Pluripotent Stem Cells

#68
20190093063
2019-03-28

Loading platform for three-dimensional tissue engineered scaffolds

#69
20190085292
2019-03-21

METHODS AND SYSTEMS FOR IMPROVING CELLS FOR USE IN THERAPY

#70
20190083544
2019-03-21

Methods and systems for conserving highly expanded cells

#71
20190054210
2019-02-21

Producing bone tissue engineered constructs

#72
20190040349
2019-02-07

Controlling pressure

#73
20190040348
2019-02-07

Controlling pressure

#74
20190031990
2019-01-31

Method for dissociating cell aggregates

#75
20190024122
2019-01-24

Apparatuses and methods using nanostraws to deliver biologically relevant cargo into non-adherent cells

#76
20190017025
2019-01-17

Methods for inducing the differentiation of blood monocytes into functional dendritic cells

#77
20190002811
2019-01-03

Droplet fluid connections

#78
20180346865
2018-12-06

Method for mechanical and hydrodynamic microfluidic transfection

#79
20180318466
2018-11-08

Methods and compositions for repair of cartilage using an in vivo bioreactor

#80
20180282695
2018-10-04

Expanding cells in a bioreactor

#81
20180237797
2018-08-23

METHODS FOR IN VITRO PRODUCTION OF PLATELETS AND COMPOSITIONS AND USES THEREOF

#82
20180224359
2018-08-09

Method of purifying tumor cells using shear stress

#83
20180201889
2018-07-19

Delivery of materials to anucleate cells

#84
20180155669
2018-06-07

Device for mechanical and hydrodynamic microfluidic transfection

#85
20180104692
2018-04-19

COMBINATION OF PHARMACOLOGICAL AND MICROFLUIDIC FEATURES FOR IMPROVED PLATELETS PRODUCTION

#86
20180066220
2018-03-08

Devices for cell culture and methods of making and using the same

#87
20180024120
2018-01-25

Compositions and methods of cell attachment

#88
20180024119
2018-01-25

Compositions and methods of cell attachment

#89
20180024118
2018-01-25

Compositions and methods of cell attachment

#90
20180024117
2018-01-25

Compositions and methods of cell attachment

#91
20180024116
2018-01-25

Compositions and methods of cell attachment

#92
20180023051
2018-01-25

Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition, system, kit and uses thereof

#93
20180023050
2018-01-25

Compositions and methods of cell attachment

#94
20180016557
2018-01-18

In vitro model for a tumor microenvironment

#95
20170354944
2017-12-14

Method for reducing the viscosity of a nanofibrillar cellulose hydrogel

#96
20170276666
2017-09-28

Multi-functional fluid flow device

#97
20170233692
2017-08-17

Method for mechanical and hydrodynamic microfluidic transfection and apparatus therefor

#98
20170183616
2017-06-29

Systems and methods for biomimetic fluid processing

#99
20170128490
2017-05-11

Method for obtaining globally activated monocytes

#100
20170121682
2017-05-04

MEGAKARYOCYTE AND PLATELET PRODUCTION FROM STEM CELLS

#101
20170058262
2017-03-02

Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells

#102
20170058257
2017-03-02

Controlling pressure

#103
20170058248
2017-03-02

Pressure manifold and culture module

#104
20170058243
2017-03-02

Droplet fluid connections

#105
20170055522
2017-03-02

Perfusion manifold assembly

#106
20170037373
2017-02-09

In vitro expansion of erythroid cells

#107
20170009194
2017-01-12

Vascularized in vitro perfusion devices, methods of fabricating, and applications thereof

#108
20170002324
2017-01-05

Surface energy directed cell self assembly

#109
20160367727
2016-12-22

SYSTEMS FOR CARTILAGE REPAIR

#110
20160333385
2016-11-17

Decreasing ornithine production to decrease high mannose glycoform content of recombinant proteins

#111
20160298082
2016-10-13

METHOD FOR OBTAINING IMMUNO-STIMULATORY DENDRITIC CELLS

#112
20160272941
2016-09-22

Fluidic device for producing platelets

#113
20160228819
2016-08-11

Electroosmotic devices for fluid handling

#114
20160228606
2016-08-11

Apparatus and process for the preparation of a biomimetic tissue prosthesis of the tympanic membrane

#115
20160201030
2016-07-14

Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

#116
20160194606
2016-07-07

Methods for inducing the differentiation of blood monocytes into functional dendritic cells

#117
20160130552
2016-05-12

METHOD FOR OBTAINING IMMUNO-SUPPRESSIVE DENDRITIC CELLS

#118
20160058910
2016-03-03

METHOD FOR PREPARING PARTICULATE DECELLULARIZED TISSUE

#119
20160002586
2016-01-07

Megakaryocyte and platelet production from stem cells

#120
20150337263
2015-11-26

Automated methods for isolating regenerative cells from adipose tissue

#121
20150315540
2015-11-05

Presaturation of supercritical COwith water for decellularization of matrices

#122
20150307848
2015-10-29

Isolation and characterization of tumor cells using shear stress measurements

#123
20150166948
2015-06-18

Fermentation of fastidious bacterial strain in perfusion suspension culture

#124
20150111240
2015-04-23

In vitro model for a tumor microenvironment

#125
20150110749
2015-04-23

Generating pluripotent cells de novo

#126
20150079048
2015-03-19

Method for in vivo, ex vivo and in vitro repair and regeneration of cartilage and collagen and bone remodeling

#127
20150024492
2015-01-22

Cell expansion system and methods of use

#128
20140248698
2014-09-04

METHOD FOR CULTURING PLURIPOTENCY-MAINTAINED SINGLY DISPERSED CELLS BY MEANS OF LAMINAR FLOW

#129
20140087424
2014-03-27

Process for cell culturing by continuous perfusion

#130
20140051123
2014-02-20

Method of increasing the productivity of eucaryotic cells in the production of recombinant FVIII

#131
20140038231
2014-02-06

Isolation and characterization of tumor cells using shear stress measurements

#132
20130330768
2013-12-12

Methods for culturing human myeloid leukaemia cells and cells derived therefrom

#133
20120276628
2012-11-01

Automated systems and methods for isolating regenerative cells from adipose tissue

#134
20120276573
2012-11-01

Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

#135
20120253456
2012-10-04

Method for preparation of artificial blood vessel using tube-type porous biodegradable scaffold having a double-layered structure and stem cell, and artificial blood vessel made by the same

#136
20120238020
2012-09-20

Megakaryocyte and platelet production from stem cells

#137
20120195862
2012-08-02

BIOMECHANICAL INDUCTION OF HEMATOPOIESIS

#138
20120014933
2012-01-19

Method for producing platelets from megakaryocytes

#139
20110275151
2011-11-10

Methods and compositions for repair of cartilage using an in vivo bioreactor

#140
20110059480
2011-03-10

Use of an in vitro hemodynamic endothelial/smooth muscle cell co-culture model to identify new therapeutic targets for vascular disease

#141
20110053262
2011-03-03

METHODS OF FABRICATING ENHANCED TISSUE-ENGINEERED CARTILAGE

#142
20110033933
2011-02-10

METHOD APPLYING HEMODYNAMIC FORCING AND KLF2 TO INITIATE THE GROWTH AND DEVELOPMENT OF CARDIAC VALVES

#143
20100285093
2010-11-11

Methods and compositions for repair of cartilage using an in vivo bioreactor

#144
20100285092
2010-11-11

Methods and compositions for repair of cartilage using an in vivo bioreactor

#145
20100285091
2010-11-11

Methods and compositions for repair of cartilage using an in vivo bioreactor

#146
20100285090
2010-11-11

Methods and compositions for repair of cartilage using an in vivo bioreactor

#147
20100267137
2010-10-21

Methods for inducing the differentiation of blood monocytes into functional dendritic cells

#148
20100216210
2010-08-26

Methods and compositions for repair of cartilage using an in vivo bioreactor

#149
20100035344
2010-02-11

Solutions for tissue engineering and methods of use

#150
20090176304
2009-07-09

Method for in vivo, ex vivo and in vitro repair and regeneration of cartilage and collagen and bone remodeling

#151
20090148876
2009-06-11

Methods for the generation of cartilage-like material by mechanical loading

#152
20090068740
2009-03-12

AMORPHOUS CELL DELIVERY VEHICLE TREATED WITH PHYSICAL/PHYSICOCHEMICAL STIMULI

#153
20090053752
2009-02-26

Use of an in vitro hemodynamic endothelial/smooth muscle cell co-culture model to identify new therapeutic targets for vascular disease

#154
20080220523
2008-09-11

Cell expansion system and methods of use

#155
20080145920
2008-06-19

Method of manufacturing a tissue-engineered prosthesis

#156
20080131934
2008-06-05

Process for cell culturing by continuous perfusion and alternating tangential flow

#157
20080075751
2008-03-27

Method for in vivo, ex vivo and in vitro repair and regeneration of cartilage

#158
20070280985
2007-12-06

Methods of Establishing Intercellular Communication in an Endothelial Cell Layer and Uses Thereof

#159
20070184033
2007-08-09

Methods and compositions for repair of cartilage using an in vivo bioreactor

#160
20070117203
2007-05-24

Modulation of stem and progenitor cell growth by oscillatory fluid flow

#161
20060216822
2006-09-28

Method for preparation of implantable constructs

#162
20060034808
2006-02-16

Amorphous cell delivery vehicle treated with physical/physicochemical stimuli

#163
20060008904
2006-01-12

Cell culture method and apparatus thereof

#164
20050095700
2005-05-05

Method for maintaining low shear in a bioprocessing system