112224 ⎘
Nucleic acids vectors Vectors characterised by the absence of particular element, e.g. selectable marker, viral origin of replication
PROCESS FOR THE MANIPULATION OF NUCLEIC ACIDS
#2Adenoviral Vectors Comprising Partial Deletions of E3
#3Gene therapy DNA vector based on gene therapy DNA vector GDTT1.8NAS12 carrying HFE therapeutic gene for enhanced expression of the therapeutic gene, method of its production and use, Escherichia coli strain JM110-NAS/GDTT1.8NAS12-HFE carrying the gene therapy DNA vector, method of its production, method of the gene therapy DNA vector production on an industrial scale
#4COMPOSITIONS AND METHODS FOR IMPROVING THE EFFICACY OF CAS9-BASED KNOCK-IN STRATEGIES
#5IMMUNOGENIC COMPOSITION
#6Means and Methods for Improved Regeneration
#7PROCESS FOR THE MANIPULATION OF NUCLEIC ACIDS
#8METHODS AND COMPOSITIONS FOR PRODUCING AN ADENOVIRUS VECTOR FOR USE WITH MULTIPLE VACCINATIONS
#9REPLICATIVE MINICIRCLE VECTORS WITH IMPROVED EXPRESSION
#10VECTORS
#11METHODS AND COMPOSITIONS FOR PRODUCING AN ADENOVIRUS VECTOR FOR USE WITH MULTIPLE VACCINATIONS
#12CONSTRUCTS, COMPOSITIONS, CELLS AND METHODS FOR INCREASED RECOMBINANT PROTEIN EXPRESSION BY TARGETED INTEGRATION AND AMPLIFICATION
#13Adenoviral Vectors Comprising Partial Deletions of E3
#14Cancer immunotherapy by delivering class II MHC antigens using a VLP-replicon
#15Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
#16SELECTION MARKER FREE METHODS FOR MODIFYING THE GENOME OF BACILLUS AND COMPOSITIONS THEREOF
#17Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
#18ADENOVIRAL- BASED BIOLOGICAL DELIVERY AND EXPRESSION SYSTEM FOR USE IN THE TREATMENT OF OSTEOARTHRITIS
#19TREATMENT METHODS USING ADENOVIRUS
#20Helper-dependent adenoviral gene therapy delivery and expression system
#21HSD17B13 variants and uses thereof
#22Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
#23Compositions and methods for enhanced gene expression in cone cells
#24METHODS FOR CREATING INTEGRATION-FREE, VIRUS-FREE, EXOGENOUS ONCOGENE-FREE IPS CELLS AND COMPOSITIONS FOR USE IN SUCH METHODS
#25Genetically Engineered Cells and Uses Thereof
#26Process for the manipulation of nucleic acids
#27Transposon-based transfection system for primary cells
#28ADENOVIRAL-BASED BIOLOGICAL DELIVERY AND EXPRESSION SYSTEM FOR USE IN THE TREATMENT OF OSTEOARTHRITIS
#29HELPER-DEPENDENT ADENOVIRAL GENE THERAPY DELIVERY AND EXPRESSION SYSTEM
#30IMPROVED VECTOR SYSTEMS FOR CAS PROTEIN AND SGRNA DELIVERY, AND USES THEREFOR
#31Genome editing without nucleases
#32Replicative minicircle vectors with improved expression
#33COMPOSITIONS AND METHODS FOR IMPROVING THE EFFICACY OF CAS9-BASED KNOCK-IN STRATEGIES
#34Cancer immunotherapy by delivering class II MHC antigens using a VLP-replicon
#35Genome Editing without Nucleases
#36Adenoviral vectors comprising partial deletions of E3
#37HSD17B13 variants and uses thereof
#38TOOLS AND METHODS FOR GENOME EDITING ISSATCHENKIA ORIENTALIS AND OTHER INDUSTRIALLY USEFUL YEAST
#39Methods and compositions for producing an adenovirus vector for use with multiple vaccinations
#40Cancer treatment
#41DELIVERY OF PACKAGED RNA TO MAMMALIAN CELLS
#42Method of detecting Polycomb Repressive Complex activity
#43Particle for the encapsidation of a genome engineering system
#44constitutive expression vector promoter screened on the basis of transcriptome sequencing, screening method thereof, and applications thereof
#45ADENOVIRAL-BASED BIOLOGICAL DELIVERY AND EXPRESSION SYSTEM FOR USE IN THE TREATMENT OF OSTEOARTHRITIS
#46Adenoviral vectors comprising partial deletions of E3
#47Methods for creating integration-free, virus-free, exogenous oncogene-free IPS cells and compositions for use in such methods
#48COMPOSITIONS AND METHODS FOR TREATMENT OF TYPE 1 DIABETES
#49ANIMAL MODELS OF CANCER
#50Means and methods for improved regeneration
#51Viral particle for the transfer of RNAs, especially into cells involved in immune response
#52GENETIC ERASERS
#53Immunomodulatory Oncolytic Adenoviral Vectors, and Methods of Production and Use Thereof for Treatment of Cancer
#54Immunogenic composition
#55TRANSGENE EXPRESSION IN AVIANS
#56Transposon-based transfection system for primary cells
#57Vectors and host cells comprising a modified SV40 promoter for protein expression
#58Treatment methods using adenovirus
#59METHODS FOR THE PRODUCTION OF IPS CELLS USING NON-VIRAL APPROACH
#60Compositions and methods for enhanced gene expression in cone cells
#61Replicative minicircle vectors with improved expression
#62Replicative minicircle vectors with improved expression
#63HER3 VACCINE VECTOR COMPOSITIONS AND METHODS OF USING THE SAME
#64Reverse genetics systems
#65HSD17B13 variants and uses thereof
#66HSD17B13 variants and uses thereof
#67Immunomodulatory oncolytic adenoviral vectors, and methods of production and use thereof for treatment of cancer
#68Human type 55 replication defective adenovirus vector, method for preparing same and uses thereof
#69Vectors
#70Polypurine tract modified retroviral vectors
#71Vectors and methods for targeted integration in loci comprising constitutively expressed genes
#72Methods and compositions for use of non-coding RNA in cell culturing and selection
#73RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS CARRYING THE MUTANT HPV- 16 E7 ANTIGEN GENE, CONSTRUCTION METHOD AND APPLICATION THEREOF
#74Adenoviral vectors comprising partial deletions of E3
#75Genome editing without nucleases
#76HPV vaccines and methods of use thereof
#77Breast cancer vaccines and methods of use thereof
#78Method of using a transgenic chicken to produce exogenous proteins in its eggs
#79Delivery of packaged RNA to mammalian cells
#80Antibiotic-free plasmid
#81Vectors and host cells comprising a modified SV40 promoter for protein expression
#82Constructs and methods for delivering molecules via viral vectors with blunted innate immune responses
#83Replicative minicircle vectors with improved expression
#84Mini-intronic plasmid DNA vaccines in combination with LAG3 blockade
#85Animal models of cancer
#86SUPERCOILED MINIVECTORS AS A TOOL FOR DNA REPAIR, ALTERATION AND REPLACEMENT
#87REPLICATIVE MINICIRCLE VECTORS WITH IMPROVED EXPRESSION
#88Compositions and methods for enhanced gene expression in cone cells
#89CONDITIONAL EXPRESSION OF TRANSGENES IN VIVO
#90Minicircle DNA vector preparations and methods of making and using the same
#91Enhanced Efficiency of Induced Pluripotent Stem Cell Generation
#92METHOD FOR EXPRESSION OF HETEROLOGOUS PROTEINS USING A RECOMBINANT NEGATIVE-STRAND RNA VIRUS VECTOR
#93Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy
#94Delivery of packaged RNA to mammalian cells
#95Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy
#96Adenoviral-based biological delivery and expression system for use in the treatment of osteoarthritis
#97Genetic variant of cytomegalovirus (CMV)
#98Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
#99Methods for the production of IPS cells using non-viral approach
#100Use of a DNA expression construct
#101Sequential administration of a replication defective adenovirus vector in vaccination protocols
#102Methods for the production of IPS cells using Epstein-Barr (EBV)-based reprogramming vectors
#103Methods and compositions for gene therapy and GHRH therapy
#104Minicircle DNA vector preparations and methods of making and using the same
#105CONDITIONAL EXPRESSION OF TRANSGENES IN VIVO
#106Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy
#107Reverse genetics systems
#108Nucleic acid construct having an ovalbumin promotor
#109Method for the production of permanent human cell lines
#110Method for selecting a high expression recombinant cell line
#111Integration-free human induced pluripotent stem cells from blood
#112Method of making induced pluripotent stem cell from adipose stem cells using minicircle DNA vectors
#113Use on minicircle vectors for cardiac gene therapy
#114Promoter and viral vector containing the same
#115Controlled activation of non-LTR retrotransposons in mammals
#116Polypurine tract modified retroviral vectors
#117Antibiotic-free plasmids
#118Compositions and methods for retinal transduction and photoreceptor specific transgene expression
#119Sequential administration of a replication defective adenovirus vector in vaccination protocols
#120Lentiviral vectors allowing RNAi mediated inhibition of GFAP and vimentin expression
#121Methods for the production of iPS cells using non-viral approach
#122DNA plasmids having improved expression and stability
#123Transgene expression in a avians