108854 ⎘
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1) Dihydrofolate reductase [DHFR] (1.5.1.3)
COMPOSITIONS AND METHODS FOR CHIMERIC LIGAND RECEPTOR (CLR)-MEDIATED CONDITIONAL GENE EXPRESSION
#2COMPOSITIONS AND METHODS FOR CHIMERIC LIGAND RECEPTOR (CLR)-MEDIATED CONDITIONAL GENE EXPRESSION
#3REGULATION OF GENE EXPRESSION BY APTAMER-MEDIATED MODULATION OF ALTERNATIVE SPLICING
#4COMPUTATIONAL METHODS TO IDENTIFY ALLOSTERIC SITES THAT MODULATE ENZYME ACTIVITY
#5TRANSPOSASE FUSION PROTEINS FOR USE IN CELL AND GENE THERAPY
#6ENGINEERING CHEMICALLY INDUCIBLE SPLIT PROTEIN ACTUATORS (CISPA)
#7ENGINEERED SPLIT DHFR-BASED METHODS AND SYSTEMS FOR SELECTING CELLS THAT HAVE STABLY ACQUIRED A HETEROLOGOUS POLYNUCLEOTIDE
#8Ribosome-Mediated Incorporation of Peptides and Peptidomimetics
#9RETINAL PROTECTIVE FACTOR 2 (RPF2) PROTEIN DELIVERED BY ADENO-ASSOCIATED VIRUS EXPRESSION
#10VECTORS INCORPORATING A COMBINATION OF PROMOTERS DRIVING SELECTABLE MARKER EXPRESSION
#11DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN
#12DHFR TUNABLE PROTEIN REGULATION
#13COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
#14CONJUGATES AND METHODS OF USE THEREOF
#15CONTROL OF PROTEIN EXPRESSION WITH TMP-PROTAC COMPOUNDS
#16M6A-COUPLED EFFECTOR PROTEIN EXPRESSION SYSTEM AND METHODS OF MAKING AND USING SAME
#17METHOD FOR PRODUCING DEMETHYLATED COMPOUND
#18COMPOSITIONS AND METHODS FOR THE TARGETING OF SOD1
#19METHODS OF REGULATING ADENO-ASSOCIATED VIRUS PRODUCTION
#20SYNTHETIC PROTEIN-LEVEL NEURAL NETWORK IN MAMMALIAN CELLS
#21MULTIPARTITE SIGNALING PROTEINS AND USES THEREOF
#22REAL-TIME CELLULAR THERMAL SHIFT ASSAY (RT-CETSA) FOR RESEARCH AND DRUG DISCOVERY
#23Protein enriched microvesicles and methods of making and using the same
#24SELECTABLE MARKER PROTEINS, EXPRESSION VECTORS, ENGINEERED CELLS AND EXTRACELLULAR VESICLES FOR THE PRODUCTION OF VIRUS-LIKE PARTICLES FOR THERAPEUTIC AND PROPHYLACTIC APPLICATIONS
#25EXOSOMAL NUCLEIC ACID VACCINE MODULARLY CONFIGURED TO HARNESS MULTIPLE ANTIGEN PRESENTATION MECHANISMS
#26TANDEM CD19 CAR-BASED COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY
#27COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OF TRANSCRIPTION
#28Ribosome-mediated incorporation of peptides and peptidomimetics
#29COMPOSITIONS AND METHODS FOR DHFR TUNABLE PROTEIN REGULATION
#30COMPOSITIONS AND METHODS FOR THE TARGETING OF SOD1
#31METHODS AND PRODUCTS FOR PRODUCING ENGINEERED MAMMALIAN CELL LINES WITH AMPLIFIED TRANSGENES
#32REGULATION OF GENE EXPRESSION BY APTAMER-MEDIATED MODULATION OF ALTERNATIVE SPLICING
#33DHFR tunable protein regulation
#34CD40L COMPOSITIONS AND METHODS FOR TUNABLE REGULATION
#35Destabilising domains for conditionally stabilising a protein
#36Small Molecules for Dual Function Positron Emission Tomography (PET) and Cell Suicide Switches
#37SYSTEMS AND METHODS FOR METABOLIC ENGINEERING
#38Compositions and methods for the targeting of SOD1
#39METHODS AND COMPOSITIONS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
#40METHODS TO ENRICH GENETICALLY ENGINEERED T CELLS
#41Cell Expression System
#42Production of soluble recombinant proteins without N-terminal methionine in
#43DOUBLE KNOCK-OUT CHO CELL LINE METHOD OF ITS GENERATION AND PRODUCING THERAPEUTIC PROTEINS THEREFROM
#44Complement Component 1s (C1s) Deficient Cells for Production of Vaccines and Biopharmaceutical Proteins
#45Programmable protein circuits in living cells
#46CRISPR HAVING OR ASSOCIATED WITH DESTABILIZATION DOMAINS
#47COMPOSITIONS AND METHODS FOR CHIMERIC LIGAND RECEPTOR (CLR)-MEDIATED CONDITIONAL GENE EXPRESSION
#48SYSTEMS AND METHODS FOR ENGINEERING ENZYMES
#49SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS
#50DRUG STABILIZED THERAPEUTIC TRANSGENES DELIVERED BY ADENO-ASSOCIATED VIRUS EXPRESSION
#51METHODS, COMPOSITIONS AND CELLS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
#52Protein enriched microvesicles and methods of making and using the same
#53Ribosome-mediated incorporation of peptides and peptidomimetics
#54Compositions and methods for selective protein degradation
#55Virus-like particle (VLP) based small molecule-protein interaction trap
#56Sensors, methods and kits for detecting NADPH based on resonance energy transfer
#57DHFR tunable protein regulation
#58Regulation of gene expression by aptamer-mediated modulation of alternative splicing
#59Multipartite signaling proteins and uses thereof
#60MULTIPARTITE SIGNALING PROTEINS AND USES THEREOF
#61CELL EXPRESSION SYSTEM
#62Virus-like particle (VLP) based small molecule-protein interaction trap
#63DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN
#64METHODS AND PRODUCTS FOR PRODUCING ENGINEERED MAMMALIAN CELL LINES WITH AMPLIFIED TRANSGENES
#65METHODS FOR IMPROVING RECOMBINANT PROTEIN EXPRESSION
#66Multipartite signaling proteins and uses thereof
#67COMBINATION THERAPY WITH AN ANTI-HYALURONAN AGENT AND THERAPEUTIC AGENT
#68CELL LINE FOR RECOMBINANT PROTEIN AND/OR VIRAL VECTOR PRODUCTION
#69Methods and compositions for preparing surfactant protein D (SP-D)
#70Methods, compositions and cells for preparing surfactant protein D (SP-D)
#71Small molecules for dual function positron emission tomography (PET) and cell suicide switches
#72Expression and purification of CRM proteins and related proteins, and protein domains
#73Selection methods for genetically-modified T cells
#74SYSTEM FOR OVER-EXPRESSING TARGET PROTEIN AND METHOD FOR OVER-EXPRESSING TARGET PROTEIN
#75Expression vector system comprising two selection markers
#76RAPID DEPLETION AND REVERSIBLE ACCUMULATION OF PROTEINS IN VIVO
#77CELL EXPRESSION SYSTEM
#78METHODS AND PRODUCTS FOR PRODUCING ENGINEERED MAMMALIAN CELL LINES WITH AMPLIFIED TRANSGENES
#79Virus-like particle (VLP) based small molecule-protein interaction trap
#80Regulation of gene expression by aptamer-mediated modulation of alternative splicing
#81Ribosome-mediated incorporation of peptides and peptidomimetics
#82CRISPR HAVING OR ASSOCIATED WITH DESTABILIZATION DOMAINS
#83Combination therapy with an anti-hyaluronan agent and therapeutic agent
#84Protein enriched microvesicles and methods of making and using the same
#85Expression vector system comprising two selection markers
#86Chemically defined cell culture media additive
#87Multipartite signaling proteins and uses thereof
#88Cell expression system
#89cell line with thyA knockout, folA knockout, and one or both of folP knockout, and folK knockout
#90METHOD FOR MASS PRODUCTION OF FACTOR VII/VIIA DERIVATIVES
#91Methods for improving recombinant protein expression
#92Methods and products for producing engineered mammalian cell lines with amplified transgenes
#93Cell expression system
#94Methods of making and using chemically self assembled-nanorings
#95Expression vector
#96Multipartite signaling proteins and uses thereof
#97cell line with knockout and knockout
#98Combination therapy with an anti-hyaluronan agent and therapeutic agent
#99Methods for improving recombinant protein expression
#100TARGETING NUCLEIC ACIDS IN MITOCHONDRIA
#101OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES
#102Expression vector system comprising two selection markers
#103Recombinant expression vector for animal cell
#104OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES
#105Methods of gene amplification and expression
#106Vector and expression cell line for mass production of recombinant protein and a process of producing recombinant protein using same
#107Cell growth
#108Nucleic acid and its use effecting ciliate tetrahymena bifunctional dihydrofolate reductase-thymidylate synthase deficiency
#109Production host cell lines
#110OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES
#111Method for Modulating the Evolution of a Polypeptide Encoded by a Nucleic Acid Sequence
#112Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues
#113Method for making recombinant protein using complementation dependent DHFR mutants
#114Compositions and methods for non-targeted activation of endogenous genes
#115Compositions and methods for non-targeted activation of endogenous genes
#116Compositions and methods for non-targeted activation of endogenous genes
#117Sulfur atom-free enzyme protein
#118Method for modulating the evolution of a polypeptide encoded by a nucleic acid sequence
#119Novel method for purification of recombinant proteins
#120Compositions and methods for non-targeted activation of endogenous genes
#121Method for modulating the production of a selected protein in vivo