108958 ⎘
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
ENGINEERED BACTERIA AND METHODS OF USE IN TUMOR REMODELING
#2ANTIBODIES THAT BIND OX40L AND ANTIBODIES THAT BIND TSLP IN COMBINATION WITH HYALURONIDASE OR A VARIANT THEREOF
#3HIGH-REACTIVITY HYDROGEL PARTICLE AND PREPARATION METHOD THEREFOR AND USE THEREOF
#4NOVEL HYALURONIDASE VARIANTS AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
#5HYALURONIDASE HYAL1 VARIANT EXHIBITING ACTIVITY IN NEUTRAL PH
#6PERTUZUMAB PLUS TRASTUZUMAB FIXED DOSE COMBINATION
#7IMMOBILIZED ENZYME NANOGEL AND PREPARATION METHOD AND APPLICATION THEREOF
#8RECOMBINANT TMEM2 EXTRACELLULAR DOMAIN AND USES THEREOF
#9PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#10PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#11PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#12PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#13PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#14CULTURE OF TUMOR INFILTRATING LYMPHOCYTES FROM TUMOR DIGEST
#15PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#16HYALURONIC ACID-PRODUCING RECOMBINANT CELLS
#17MANIPULATION OF ZONA PELLUCIDA TO FACILITATE DELIVERY OF NUCLEIC ACIDS FOR GENE EDITING IN EMBRYO
#18METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE
#19METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE
#20N-terminal and/or C-terminal Cleaved Soluble PH20 Polypeptide and Use Thereof
#21VIRAL PARTICLES WITH MEMBRANE-BOUND HYALURONIDASE
#22MULTIFUNCTIONAL MOLECULES AND USES THEREOF
#23PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#24ENGINEERED ONCOLYTIC HERPESVIRUSES
#25ONCOLYTIC ADENOVIRUSES FOR TREATING CANCER
#26A PRODUCTION OF A PURIFIED MODIFIED BACTERIAL HYALURONIDASE POLYPEPTIDE, PHARMACEUTICAL COMPOSITIONS AND THEIR USES
#27HYALURONIDASE POLYPEPTIDE FOR USE IN THE TREATMENT OR PROPHYLAXIS OF A NEURODEGENERATIVE DISEASE
#28FACILITATED DELIVERY OF CONCENTRATED ANTIBODY FORMULATIONS USING HYALURONIDASE
#29DIGITAL MICROBIOLOGY
#30PH20 polypeptide variants, formulations and uses thereof
#31PH20 polypeptide variants, formulations and uses thereof
#32GENE FOR EFFICIENTLY EXPRESSING HYALURONIC ACID HYDROLASE AND EXPRESSION METHOD THEREOF
#33PH20 polypeptide variants, formulations and uses thereof
#34PH20 polypeptide variants with a modification at position 309 of the PH20 polypeptide and a method of making thereof
#35PH20 polypeptide variants, formulations and uses thereof
#36PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#37PH20 polypeptide variants, formulations and uses thereof
#38PH20 polypeptide variants, formulations and uses thereof
#39SOLUBLE HYALURONIDASE GLYCOPROTEIN (sHASEGP), PROCESS FOR PREPARING THE SAME, USES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF
#40PH20 polypeptide variants, formulations and uses thereof
#41PH20 polypeptide variants, formulations and uses thereof
#42PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
#43PH20 polypeptide variants, formulations and uses thereof
#44NOVEL HYALURONIDASE VARIANTS WITH IMPROVED STABILITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
#45PH20 polypeptide variants, formulations and uses thereof
#46Method for producing recombinant hyaluronidase
#47A MODIFIED BACTERIAL HYALURONIDASE POLYPEPTIDE, PRODUCTION PROCESS, PHARMACEUTICAL COMPOSITIONS AND THEIR USES
#48PH20 polypeptide variants, formulations and uses thereof
#49HYALURONIDASE COMPOSITIONS AND METHODS OF USING SAME TO TREAT FIBROSIS
#50METHODS AND COMPOSITIONS TO PREVENT AND TREAT INFLAMMATION AND ALLERGIC REACTIONS
#51SUBCUTANEOUS DELIVERY OF MESSENGER RNA
#52High-efficiency synthesis and high-purity hyaluronic acid, and recombinant for oligosaccharide thereof
#53COMBINATION THERAPY WITH A HYALURONAN-DEGRADING ENZYME AND AN IMMUNE CHECKPOINT INHIBITOR
#54PHARMACEUTICAL COMPOSITION FOR SUBCUTANEOUS INJECTION COMPRISING HUMAN HYALURONIDASE PH20 VARIANT AND DRUG
#55Engineered heme-binding compositions and uses thereof
#56Digital microbiology
#57COMPOSITIONS AND METHODS FOR TARGETING TUMOR-ASSOCIATED EXTRACELLULAR MATRIX COMPONENTS TO IMPROVE DRUG DELIVERY
#58Stable Formulations of Programmed Death Receptor 1 (PD-1) Antibodies and Hyaluronidase Variants and Fragments Thereof and Methods of Use Thereof
#59Pertuzumab plus trastuzumab fixed dose combination
#60PHARMACEUTICAL COMPOSITION FOR SUBCUTANEOUS INJECTION COMPRISING HUMAN HYALURONIDASE PH20 VARIANT AND DRUG
#61PH20 polypeptide variants, formulations and uses thereof
#62PH20 polypeptide variants, formulations and uses thereof
#63Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide
#64MULTIFUNCTIONAL MOLECULES AND USES THEREOF
#65MULTISPECIFIC MOLECULES COMPRISING A NON-IMMUNOGLOBULIN HETERODIMERIZATION DOMAIN AND USES THEREOF
#66PH20 polypeptide variants, formulations and uses thereof
#67PH20 polypeptide variants, formulations and uses thereof
#68Engineered heme-binding compositions and uses thereof
#69Methods and compositions to prevent and treat inflammation and allergic reactions
#70COMBINATION OF AN ANTIBODY THAT BINDS TO THE P19 SUBUNIT OF HUMAN IL-23 AND A HYALURONIDASE ENZYME
#71Oncolytic adenoviruses for treating cancer
#72SYNTHETIC BACTERIA AND METHODS OF USE
#73Subcutaneous delivery of messenger RNA
#74Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
#75COMBINATION THERAPY WITH AN ANTI-HYALURONAN AGENT AND THERAPEUTIC AGENT
#76Digital microbiology
#77Controlling metabolism by substrate cofeeding
#78Bacterial hyaluronidase and process for its production
#79Engineered heme-binding compositions and uses thereof
#80Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
#81Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor
#82TREATMENT OF INFLAMMATORY CONDITIONS BY MODULATION OF HYALURONAN AND HYALURONIDASE ACTIVITY
#83Combination therapy with an anti-hyaluronan agent and therapeutic agent
#84STABILIZER FOR HYALURONIDASE AND LIQUID FORMULATION COMPRISING HYALURONIDASE
#85Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
#86Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor
#87Extracellular hyaluronidase from
#88Adenoassociated virus vectors for the treatment of lysosomal storage disorders
#89Method of constructing a recombinant that can produce specific-molecular-weight hyaluronic acids
#90PH20 polypeptide variants, formulations and uses thereof
#91Bacterial hyaluronidase and process for its production
#92Engineered heme-binding compositions and uses thereof
#93Treatment of inflammatory conditions with hyaluronan disaccharide
#94Stabilizer for hyaluronidase and liquid formulation comprising hyaluronidase
#95Hyaluronic Acid Decomposition-Promoting Factor and Inhibitor Thereof
#96Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
#97Bacillus, hyaluronidase, and uses thereof
#98SOLUBLE GLYCOSAMINOGLYCANASES AND METHODS OF PREPARING AND USING SOLUBLE GLYCOSAMINOGLYCANASES
#99THERMALLY STABLE PH20 HYALURONIDASE VARIANTS AND USES THEREOF
#100Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
#101RECOMBINANT HUMAN NAGLU PROTEIN AND USES THEREOF
#102Methods for reducing intraocular pressure by administering a soluble hyaluronidase glycoprotein (sHASEGP)
#103PH20 polypeptide variants, formulations and uses thereof
#104Combination therapy with an anti-hyaluronan agent and therapeutic agent
#105PH20 polypeptide variants, formulations and uses thereof
#106Methods for improving the tissue penetration of a drug by administering the drug together with a hyaluronidase protein
#107Extended Soluble PH20 Polypeptides and uses thereof
#108Recombinant human NaGlu protein and uses thereof
#109Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
#110Methods for treating edema by administering a Soluble Hyaluronidase Glycoprotein (sHASEGP)
#111EXTRACELLULAR YALURONIDASE FROM STREPTOMYCES KOGANEIENSIS
#112Neutral active soluble truncated PH20 polypeptides and uses thereof
#113Hyaluronidase and factor VIII compositions
#114Oncolytic adenoviruses for treating cancer
#115EXTRACELLULAR YALURONIDASE FROM STREPTOMYCES KOGANEIENSIS
#116Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
#117Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof
#118Methods and materials for reducing biofilms
#119Hyaluronidase and method of use thereof
#120Extended soluble PH20 polypeptides and uses thereof
#121Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
#122Methods for treating a disease characterized by an excess of hyaluronan by administering a soluble hyaluronidase glycoprotein (sHASEGP)
#123Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
#124Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
#125Human plasma hyaluronidase
#126Synthetic heparanase molecules and uses thereof
#127Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
#128PH20 polypeptide variants, formulations and uses thereof