112566 ⎘
Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
Modulation of Abeta levels by beta-secretase BACE2
#1502MONITOR PROTEIN FOR MEASURING PROCESSING OF PROTEIN
#1503Secreted proteins as early markers and drug targets for autoimmunity, tumorigenesis and infections
#1504Assays using amyloid precursor proteins with modified beta-secretase cleavage sites to monitor beta-secretase activity
#1505Hepatitis C virus NS2/3 activity assay
#1506Methods for identifying modulators of hedgehog autoprocessing
#1507PSEUDOMONAS AERUGINOSA L-D CARBOXYPEPTIDASE A, EXPRESSION AND ACTIVITY
#1508Self-quenching homofluorophore compositions for detecting enzyme activity
#1509Method for measuring a protein
#1510Diagnostics And Therapeutics For Diseases Associated With Arginyl Aminopeptidase Rnpep (Rnpep)
#1511Methods for quantitative proteome analysis of glycoproteins
#1512Methods for modulating proteins not previously known as proteases
#1513Signal amplification using a synthetic zymogen
#1514Diagnostics and therapeutics for diseases associated with kallikrein 8 (klk8)
#1515Hereditary angioedema type III
#1516Diagnostic method for identifying carriers of the Marburg I variant of factor VII-activating protease (FSAP) on the basis of differential modulation of FSAP activity
#1517Method and compositions for identifying anti-hiv therapeutic compounds
#1518Method and apparatus for monitoring enzyme mixtures
#1519METHODS FOR TRANSFERASES
#1520Beta-secretase substrates and uses thereof
#1521Method of cancer treatment by p53 protein control
#1522Luminogenic and nonluminogenic multiplex assay
#1523Purified active HCV NS2/3 protease
#1524Method of determining chymase activity with secretory leukocyte protease inhibitor
#1525Substrates and methods for assaying deubiquitinating enzymes
#1526Assay methods and systems
#1527VIRAL PROTEASE
#1528Purified active HCV NS2/3 protease
#1529Use of cathepsin z inhibitors for the treatment of rhuematoid arthritis and other autoimmune diseases
#1530Analytical method for detecting alkaline sphingomyelinase and kit for use in such method
#1531Method for generating F(ab′)2 antibody fragments
#1532Metalloprotease assay
#1533Methods of treatment and uses for CaMKII and its interaction with HDACs and calpain
#1534Pregnancy-associated plasma protein-A2 (PAPP-A2)
#1535Test system for the determination of in-vivo active hemostasis proteases in biological fluids and/or the usage thereof to determine the in-vivo activation of hemostasis
#1536Activity-based probes and methods of their preparation and use
#1537Nucleic acids encoding human TNF-α convertase
#1538Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
#1539Detection of secreted aspartyl proteases from species
#1540Methods for the treatment of chronic pain and compositions therefor
#1541Methods and compositions for cell culture
#1542Screening assays for agents that alter inhibitor of apoptosis (IAP) protein regulation of caspase activity
#1543Substrates, sensors, and methods for assessing conditions in females
#1544COMPOSITIONS COMPRISING ANTIBODIES TO HUMAN FGL2
#1545Method of treating cells
#1546Signal amplification using a synthetic zymogen
#1547Cross-reactive sensors
#1548CELL-BASED FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET) ASSAYS FOR CLOSTRIDIAL TOXINS
#1549Plant extracts and dermatological uses thereof
#1550Clp-protease as target for herbicides
#1551Nucleic acid aptamer-based compositions and methods
#1552Methods for achieving a protective ACE2 expression level to treat kidney disease and hypertension
#1553Cell-permeable fluorescent proteins
#1554Non-invasive enzyme screen for tissue remodeling associated conditions
#1555Methods of identifying compounds that inhibit Notch cleavage
#1556Proteolytic and covalent antibodies
#1557Rennets
#1558Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof
#1559Diagnostics and therapeutics for diseases associated with n-acetylated alpha-linked acidic dipeptidase 2(naaladase 2)
#1560Method of treating skin by delivering specific protein stabilizers/protectors to skin proteins and methods of selecting said stabilizers
#1561Process for treatment of protein samples
#1562Diagnostics and therapeutics for diseases associated with kallikrein 9 (klk9)
#1563Biocatalytic material comprising multilayer enzyme coated fiber
#1564High stability, high activity coatings and processes for using same
#1565Process for preparing multilayer enzyme coating on a fiber
#1566Method of screening compounds
#1567Gamma secretase notch biomarkers
#1568Fluorescence polarization assays for binding of caspase inhibitors and probes therefor
#1569Human PRSS11-like S2 serine protease and uses thereof
#1570Substrate polyeptides for von Willebrand factor cleaving protease ADAMTS-13
#1571Cellular libraries of peptide sequences (CLiPS) and methods of using the same
#1572Function and regulation of ADAMTS-1
#1573Method for PR-39 peptide mediated selective inhibition of IkappaBalpha degradation
#1574Methods of determining compounds useful in the treatment of bipolar disorder and methods of treating such disorders
#1575Method for measuring protease activity of transglutaminase and transglutaminase composition
#1576Selective Apoptotic Induction in Cancer Cells Including Activation of Procaspase-3
#1577Cell-based luminogenic and nonluminogenic proteasome assays
#1578Detection of plasma ACE2
#1579Method for screening for protease modulators
#1580MASP-2, a complement-fixing enzyme, and uses for it
#1581Inhibitors of amyloid precursor protein processing
#1582Novel Integrin Ligand ITGL-TSP
#1583Method for stabilizing leuco dye
#1584Novel Integrin Ligand ITGL-TSP
#1585Whole cell assay involving cathepsin s
#1586Coagulation proteins, coagulation-anticoagulation protein complexes, derivatives thereof and their uses
#1587Novel treatment
#1588Methods and compositions for treatment of tumors using nucleic acid ligands to platelet-derived growth factor
#1589Whole cell assay for inhibitors of cathepsin k
#1590Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds
#1591Fungal proteins and nucleic acids encoding same
#1592Peptide Conjugates and Fluorescence Detection Methods for Intarcellular Caspase Assay
#1593Detection of spectrin and spectrin proteolytic cleavage products in assessing nerve cell damage
#1594Methods and kits for the diagnosis of acute coronary syndrome
#1595Cross-beta structures on microbial organisms
#1596Protease regulator screening assay
#1597Phex substrates and methods using same
#1598Diagnostics and therapeutics for diseases associated with mosaic serine protease (msp)
#1599Salicylamide-lanthanide complexes for use as luminescent markers
#1600Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1601Stabilization of T4 endonuclease V
#1602Method for analyzing cell free notch cleavage and method for drug screening
#1603Methods and kits useful for the simplification of complex peptide mixtures
#1604Use of coagulation proteins to lyse clots
#1605Method for identifying and culture medium
#1606Method for chemical and enzymatic treatment of posttranslationally modified proteins bound to a protein chip
#1607Serine proteases with altered sensitivity to activity-modulating substances
#1608Method for detecting escherichia coli
#1609Peptide conjugates and fluorescence detection methods for intracellular caspase assay
#1610Bcl2L12 polypeptide activators and inhibitors
#1611Anthrax bioassays and methods of treating and diagnosing anthrax infection
#1612Chemo-enzymatic process for proteome-wide mapping of post-translational modification
#1613Compositions and methods for screening pro-apoptotic compounds
#1614Protease detection assay
#161527877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552, and 65577 molecules and uses therefor
#1616Caspase 10 as target for monitoring and treatment of diseases
#1617Method for the detection of proteolytic enzymes
#1618Secondary binding site of dipeptidyl peptidase IV (DP IV)
#1619Anthrax lethal factor is a MAPK kinase protease
#1620Method for determining the substrate specificity of an enzyme
#1621Methods of using molecular constructs for detection of biochemical reactions
#1622Methods for identifying inhibitors of neurotoxins
#1623Peptide substrates of a proteolytic ADAM33 polypeptide and assays using the same
#1624Methods for detecting and inactivating a prion
#1625Compositions and methods for detecting protease activity
#1626Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus
#1627Caspase 9 activation and uses therefor
#1628Methods and compositions to diagnose disease using concatenated oligopeptide standard
#1629Proteome-wide mapping of post-translational modifications using endopeptidases
#1630Methods and compositions for modulating prostasin
#1631Optical monitoring of cleaving enzyme activity
#1632Methods for treating pervasive development disorders
#1633Bioluminescent protease assay with modified aminoluciferin or derivatives thereof
#1634Methods for detecting TAFIa or TAFIai
#1635Novel beta-secretase and modulation of beta-secretase activity
#1636Methods for treating pervasive development disorders
#1637Methods for the treatment of chronic pain and compositions therefor
#1638Methods and reagents for protease inhibition
#1639Stable chromogenic test reagent and its use in coagulation-diagnostic tests
#1640Methodology of estimating the conformation of a protein by proteolysis
#1641Growth hormone variations in humans and its uses
#1642Detection of protease-resistant prion protein following a spontaneous transformation reaction
#1643Method of screening compound affecting amyloid beta production
#1644GFP-SNAP25 fluorescence release assay for botulinum neurotoxin protease activity
#1645Method of reducing complement - mediated disruption of cells
#1646Detection and quantification of modified proteins
#1647Homogenous assay for enzymatic activity
#1648Affinity labeling of serine proteases for simultaneous detection of multiple serine protease activity levels
#1649Assay for tissue factor in a sample
#1650Insulin-like growth factor binding protein-4 protease
#1651Analytical method for detecting alkaline sphingomyelinase and kit for use in such method
#1652Detection of protease enzymes
#1653Engineered proteases for affinity purification and processing of fusion proteins
#1654Mass spectroscopic method for comparing protein levels in two or more samples
#1655Novel serine protease
#1656Non nucleoside reverse transcriptase inhibitors
#1657Protozoan rhomboid proteins
#1658Method of treating multiple sclerosis with anti-K6 antibody
#1659Apparatuses and methods for determining protease activity
#1660Phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity
#1661Bioluminescent caspase assay compounds
#1662Molecular modification assays
#1663Protein interaction reporter agents and methods for using same
#1664Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
#1665Method and compositions for identifying anti-hiv therapeutic compounds
#1666System for protease mediated protein expression
#1667Method for single oxygen atom incorporation into digested peptides using peptidases
#1668Ubiquitin ligase assay
#166917867, a novel human aminopeptidase
#1670Tenascin-C nucleic acid ligands
#1671Novel tumor suppressor gene and compositions and methods for making and using the same
#1672Modulation of stem cell differentiation by modulation of caspase-3 activity
#1673System for cell-based screening
#1674Systematic evolution of ligands by exponential enrichment: Chemi-SELEX
#1675Compounds for enzyme inhibition
#1676Insulin degrading enzyme assays for treatment of alzheimer's disease
#1677High affinity TGFbeta nucleic acid ligands and inhibitors
#1678Methods and compositions for modulating hepatocyte growth factor activation
#1679Methods and kits for measuring ADAMTS13/FXI complexes
#1680Methods and compositions involving sortase B
#1681Luciferyl peptide substrate
#1682Antibodies, assay method by using them and judgment method for pancreas cancer
#1683Methods for detecting breast and ovarian cancer
#1684Detecting cell membrane protein endocytosis
#1685Method for the identification of modulators of a secretase activity
#1686Methods for the treatment of osteoarthritis and compositions thereof
#1687Enzymatic activities in chemokine-mediated inflammation
#1688Fluorescence polarization assays for determining clostridial toxin activity
#1689Lanthanide-based substrates and methods for determining clostridial toxin activity
#1690Novel bicyclic hydroxamates as inhibitors of histone deacetylase
#1691Method of identification and quantification of proteins, isoforms of the angiotensin I converting enzyme
#1692Method of screening cell death modulators
#1693Destructible surfactants and uses thereof
#1694Kit for determining the acetylation level of a peptide based on sensitivity of the peptide to peptidase
#1695Method for assessing proteolytic enzyme activity using ubiquitin fusion substrate
#1696Gamma secretase substrates and in vitro assays
#1697Apparatus for the detection of pepsin
#1698Chromogenic compounds, and use thereof as enzyme substrates
#1699Monitor protein for measuring processing of protein
#1700Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS
#1701Method of inhibiting angiogenesis
#1702Monitoring heart failure
#1703Mass spectrometry-based methods for detection and differentiation of botulinum neurotoxins
#1704Luminescent polymers and methods of use thereof
#1705Cleavage of VEGF and VEGF receptor by wild-type and mutant proteases
#1706Methods for measuring ADAMTS13 activity and protein on platelets and in plasma
#1707Methods for identification, and compounds useful for the treatment of degenerative & inflammatory diseases
#1708Modulation of stem cell differentiation by modulation of caspase-3 activity
#1709Novel 27875, 22025, 27420, 17906, 16319, 55092 and 10218 molecules and uses therefor
#1710Method of measuring neprilysin activity
#1711Fluorogenic enzyme activity assay methods and compositions using fragmentable linkers
#1712High throughput assays for the proteolytic activities of clostridial neurotoxins
#1713Method for detecting the presence or risk of prostate cancer by detecting products of psa or klk2
#1714Proteomic analysis
#1715Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1716Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1717Mycoplasma polypeptides
#1718Methods, compositions and compound assays for inhibiting amyloid-beta protein production
#1719Methods and compositions for activating VEGF-D and VEGF-C
#1720Novel treatment
#1721Rapid test for hemolytic streptococcus
#1722CD-10 activated prodrug compounds
#1723Detection of proteases and screening for protease inhibitors
#1724Methods for treating congestive heart failure
#1725Proteomic analysis
#1726Methods for identifying a compound that inhibits the procession of amyloid-beta protein production in a mammalian cell expressing APP and overexpressing a G-protein coupled receptor in the cell
#1727Novel tumor suppressor gene and compositions and methods for making and using the same
#1728Method of decomposing protein with sulfonic acid compound
#1729Proteases and uses thereof
#1730Proteolytic biomarkers for traumatic injury to the nervous system
#1731Methods of identifying dermal papilla cells
#1732Chemosensitivity measurement using caspase activity
#1733Multilayer reagent test strips and methods for using the same to quantify glycated protein in a physiological sample
#1734Inhibition of anthrax lethal factor protease
#1735Peptides derived from cadherin and methods of use thereof
#1736Methods, compositions, and kits for analysis of enzyme activity in cells
#1737Ligand-containing micelles and uses thereof
#1738Assay system for screening protease inhibitors
#1739Transgenic mouse whose genome comprises an APP having a mutation at amino acid 664
#1740Method for detecting the von Willebrand factor-cleaving protease activity of ADAMTS-13
#1741Method and compositions for identifying anti-HIV therapeutic compounds
#1742Compositions and methods for cleaving IAP
#1743Methods for high resolution identification of solvent accessible amide hydrogens in polypeptides and for characterization of polypeptide structure
#1744Screening method for orthopoxvirus antivirals
#1745Methods and reagents for identifying inhibitors of viral protease activity
#1746Mutational profiles in HIV-1 protease correlated with phenotypic protease inhibitor resistance
#1747Fluorescence polarization assay to detect protease cleavage
#1748Methods of screening for compounds that modulate TAFIa activity, compounds, and methods of using the compounds
#1749Protease assay for therapeutic drug monitoring
#1750Method for determining mucosal neutrophil counts in neutropenia patents
#1751Novel "Cleave-N-Read" system for protease activity assay and methods of use thereof
#1752Method of diagnosing ovarian endometriosis
#1753Cyanine dyes
#1754Compositions and methods for the screening pro-apoptotic compounds
#1755Nucleic acids encoding dendritic cell transmembrane serine protease
#1756Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds
#1757Novel integrin ligand ITGL-TSP
#1758Modulators of angiogenesis
#1759Hypotensors
#1760Compounds and methods for identifying compounds which inhibit a new class of aspartyl proteases
#1761Non nucleoside reverse transcriptase inhibitors
#1762Anthrax lethal factor is a mapk kinase protease
#1763Alzheimer's disease secretase, APP substrates thereof, and uses thereof
#1764Rapid assay to detect ADAMTS-13 activity
#1765Selective substrates for matrix metalloproteinases
#1766Biological markers and diagnostic tests for angiotensin converting enzyme inhibitor and vasopeptidase inhibitor-associated angioedema
#1767Device for detecting bacterial contamination and method of use
#1768Secondary binding site of dipeptidyl peptidase IV (DPIV)
#1769Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures
#1770Multiplex protease profiling
#1771Biological entities and the pharmaceutical and diagnostic use thereof
#1772Microtiter plate format device and methods for separating differently charged molecules using an electric field
#1773Modulating angiogenesis
#1774Methods and compositions relating to modulating amyloid precursor protein cleavage
#1775Xanthene dyes
#1776Compositions comprising antibodies to human FgI2
#1777Nucleic acid ligand complexes
#1778Assays for the detection of microtubule depolymerization inhibitors
#1779High-throughput assay for virus entry and drug screening
#1780Homo-doubly labeled compositions for the detection of enzyme activity in biological samples
#1781Methods for the early diagnosis of ovarian cancer
#1782Fitness assay and associated methods
#1783Methods for determinging the influence of protein binding on antiretroviral activity
#1784Methods for diagnosing and treating autoimmune disease
#1785Fungal proteins and nucleic acids encoding same
#1786MASP-2, a complement-fixing enzyme, and uses for it
#1787Synthetic and recombinant substrates for the detecion of the von willebrand factor-cleaving protease
#1788Method for detecting microorganisms
#1789Inhibitors of amyloid precursor protein processing
#1790Assays for identifying modulators of rhomboid polypeptides
#1791System and method for the analysis of bodily fluids
#1792Method of measurement of protease and thin membranes used for said method
#1793Affinity labeling of enzymes for detection of enzyme activity level in living cells
#1794Truncation SELEX method
#1795HCV NS3-NS4A protease resistance mutants
#1796Cell-based assay for identifying peptidase inhibitors
#1797Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
#1798Method of mass spectrometry
#1799Imaging the activity of extracellular protease in cells using mutant anthrax toxin protective antigens that are cleaved by specific extracellular proteases
#1800Fluorogenic protease substrates