112695 ⎘
Reaction characterised by the enzymatic activity; Phosphoric diester hydrolysing, i.e. nuclease Endonuclease
DETECTING OVARIAN CANCER
#2T CELL-TARGETED T CELLS
#3DETERMINATION OF POLYMORPHISMS USING ISOTHERMAL NUCLEIC ACID AMPLIFICATION
#4METHYLATION DETECTION WITH A NON-NATURAL/UNNATURAL BASE
#5POLYNUCLEOTIDE ENRICHMENT USING CRISPR-CAS SYSTEM
#6SINGLE MOLECULE NUCLEIC ACID DETECTION BY MISMATCH CLEAVAGE
#7DETERMINATION OF POLYMORPHISMS USING ISOTHERMAL NUCLEIC ACID AMPLIFICATION
#8METHODS FOR THE IDENTIFICATION AND CHARACTERIZATION OF DOUBLE-STRAND BREAK SITES AND COMPOSITIONS AND USES THEREOF
#9RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE
#10Multiplex Amplification Detection Assay II
#11Methods Of Producing Nucleic Acids Using Oligonucleotides Modified By A Stimulus
#12METHODS AND COMPOSITIONS FOR TARGET DETECTION
#13METHODS FOR AMPLIFICATION OF NUCLEIC ACIDS WITH ENDONUCLEASE-MEDIATED SHIFTING EQUILIBRIUM (EM-SEQ)
#14POLYNUCLEOTIDE AMPLIFICATION USING CRISPR-CAS SYSTEMS
#15RNA-guided nucleases and active fragments and variants thereof and methods of use
#16SINGLE NUCLEOTIDE DETECTION METHOD AND ASSOCIATED PROBES
#17RNA-GUIDED CAS NUCLEASES AND USES THEREOF IN DIAGNOSTICS AND THERAPY
#18HOMOLOGOUS RECOMBINATION VIA TRANSCRIPTIONAL ACTIVATION
#19DETECTING OVARIAN CANCER
#20HOMOLOGOUS RECOMBINATION VIA TRANSCRIPTIONAL ACTIVATION
#21Analysis of Chromatin Using a Nicking Enzyme
#22SYSTEMS AND METHODS FOR ANALYZING SEQUENCE DATA
#23Methods for Detecting Site-Specific and Spurious Genomic Deamination Induced by Base Editing Technologies
#24RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE
#25COMPOSITIONS AND METHODS FOR HIGH FIDELITY ASSEMBLY OF NUCLEIC ACIDS
#26TRANSPOSITION INTO NATIVE CHROMATIN FOR PERSONAL EPIGENOMICS
#27Methods of producing nucleic acids using oligonucleotides modified by a stimulus
#28METHODS OF IDENTIFYING AND CHARACTERIZING GENE EDITING VARIATIONS IN NUCLEIC ACIDS
#29RNA-guided nucleases and active fragments and variants thereof and methods of use
#30RNA-guided nucleases and active fragments and variants thereof and methods of use
#31RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE
#32APPLICATION OF EPIGENETIC CHROMOSOMAL INTERACTIONS IN CANCER DIAGNOSTICS
#33METHOD FOR DETERMINATION OF 3D GENOME ARCHITECTURE WITH BASE PAIR RESOLUTION AND FURTHER USES THEREOF
#34PRODUCTION AND TRACKING OF ENGINEERED CELLS WITH COMBINATORIAL GENETIC MODIFICATIONS
#35VITRO ISOLATION AND ENRICHMENT OF NUCLEIC ACIDS USING SITE-SPECIFIC NUCLEASES
#36Transposition of native chromatin for personal epigenomics
#37Multiplex amplification detection assay II
#38Analysis of chromatin using a nicking enzyme
#39Compositions and methods for high fidelity assembly of nucleic acids
#40Method for constructing library of cell-free DNAs in body fluids and application thereof
#41Transposition of Native Chromatin for Personal Epigenomics
#42Systems and methods for analyzing sequence data
#43SINGLE MOLECULE NUCLEIC ACID DETECTION BY MISMATCH CLEAVAGE
#44Methods for the identification and characterization of double-strand break sites and compositions and uses thereof
#45Method for identifying gene fusions by circle cDNA amplification
#46Detecting ovarian cancer
#47METHOD FOR PURIFYING TOTAL MRNA FROM TOTAL RNA USING SLFN13
#48METHODS FOR AMPLIFICATION OF NUCLEIC ACIDS WITH ENDONUCLEASE-MEDIATED SHIFTING EQUILIBRIUM (EM-SEQ)
#49Small RNA detection method based on small RNA primed xenosensor module amplification
#50COMPOSITIONS AND METHODS FOR IMPROVED DETECTION OF GENOMIC EDITING EVENTS
#51Homologous recombination via transcriptional activation
#52Method for direct quantification of nucleic acids in real time qPCR
#53Transposition of native chromatin for personal epigenomics
#54Methods of producing nucleic acids using oligonucleotides modified by a stimulus
#55Multiplexed Screening
#56DIGITAL NUCLEASE DETECTION COMPOSITIONS AND METHODS
#57Multiplex amplification detection assay II
#58UNBIASED DETECTION OF NUCLEIC ACID MODIFICATIONS
#59Methods for detecting site-specific and spurious genomic deamination induced by base editing technologies
#60METHOD, LYSIS SOLUTION AND KIT FOR SELECTIVELY DEPLETING ANIMAL NUCLEIC ACIDS IN A SAMPLE
#61Single nucleotide detection method and associated probes
#62Polynucleotide amplification using CRISPR-Cas systems
#63CRISPR effector system based diagnostics for virus detection
#64In vitro isolation and enrichment of nucleic acids using site-specific nucleases
#65Molecular computing component and method of molecular computing
#66POLYNUCLEOTIDE ENRICHMENT USING CRISPR-CAS SYSTEM
#67RIBONUCLEOPROTEIN-BASED IMAGING AND DETECTION
#68Methods of identifying and characterizing gene editing variations in nucleic acids
#69Nucleic acid detection method
#70ENRICHMENT OF DNA COMPRISING TARGET SEQUENCE OF INTEREST
#71Genome editing reagents and their use
#72METHODS OF GENOME SEQUENCING AND EPIGENETIC ANALYSIS
#73Application of epigenetic chromosomal interactions in cancer diagnostics
#74SCARLESS DNA ASSEMBLY AND GENOME EDITING USING CRISPR/CPF1 AND DNA LIGASE
#75Methods of nucleic acid sequencing
#76Transportation of native chromatin for personal epigenomics
#77Transposition of native chromatin for personal epigenomics
#78Methods of enhancing chromosomal homologous recombination
#79Analysis of chromatin using a nicking enzyme
#80Assembly system for a eukaryotic cell
#81MICROFLUIDIC SEQUENCING TECHNIQUES
#82Multiplex amplification detection assay II
#83Nucleic acid detection combining amplification with fragmentation
#84RNA-directed DNA cleavage by the Cas9-crRNA complex
#85Methods for genome assembly and haplotype phasing
#86Methods for genotyping
#87Identification of genetic modifications
#88METHODS AND COMPOSITIONS FOR TARGET DETECTION
#89EDITING MITOCHONDRIAL DNA
#90Method for using heat-resistant mismatch endonuclease
#91RNase H-Based Assays Utilizing Modified RNA Monomers
#92METHODS AND COMPOSITIONS FOR ENHANCED NUCLEASE-MEDIATED GENOME MODIFICATION AND REDUCED OFF-TARGET SITE EFFECTS
#93Transposition of native chromatin for personal epigenomics
#94TRANSPOSITION OF NATIVE CHROMATIN FOR PERSONAL EPIGENOMICS
#95DETERMINATION OF POLYMORPHISMS USING ISOTHERMAL NUCLEIC ACID AMPLIFICATION
#96Capture of nucleic acids using a nucleic acid-guided nuclease-based system
#97Methods and compositions for generating CRISPR/Cas guide RNAs
#98Probes for improved melt discrimination and multiplexing in nucleic acid assays
#99Methods of analyzing virus-derived therapeutics
#100Systems and methods for analyzing sequence data
#101Multiplex amplification methods
#102Methods and compositions to generate unique sequence DNA probes, labeling of DNA probes and the use of these probes
#103RNA-directed DNA cleavage by the Cas9-crRNA complex
#104Method, lysis solution and kit for selectively depleting animal nucleic acids in a sample
#105Methods and compositions for segregating target nucleic acid from mixed nucleic acid samples
#106Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-seq)
#107Materials and methods for the synthesis of error-minimized nucleic acid molecules
#108Method for the colorimetric detection of contamination with nucleases
#109Method for attaching a counter sequence to a nucleic acid sample
#110Methods of nucleic acid sequencing
#111Method for Sensitive Detection of Target DNA Using Target-Specific Nuclease
#112DNA glycosylase/lyase and AP endonuclease substrates
#113Endonucleases
#114Polynucleotide enrichment using CRISPR-Cas systems
#115Single molecule sequencing with two distinct chemistry steps
#116Systems and methods for analyzing sequence data
#117Method for attaching a counter sequence to a nucleic acid sample
#118Cell free DNA diagnostic testing standards
#119Endonucleases
#120Method for exclusive selection of circularized DNA from monomolecular DNA in circularizing DNA molecules
#121Single molecule sequencing with two distinct chemistry steps
#122NOx control during engine idle-stop operations
#123Method of Preparing Magnetic Bead Type Nasopharyngeal Enzyme Immunoassay Reagents by Polymerase Chain Reaction
#124NUCLEIC ACID DETECTION BY OLIGONUCLEOTIDE PROBES CLEAVED BY BOTH EXONUCLEASE AND ENDONUCLEASE
#125Method of detecting ethylated thymidine DNA adducts
#126Compositions and Methods For High Fidelity Assembly of Nucleic Acids
#127Methods for sequencing polynucleotides
#128Filtering small nucleic acids using permeabilized cells
#129Method for genome complexity reduction and polymorphism detection
#130Molecular biosensors capable of signal amplification
#131SYSTEMS, DEVICES, AND METHODS FOR AUTOMATED CHARACTERIZATION OF A NUCLEIC ACID MOLECULE
#132Methods and compositions for segregating target nucleic acid from mixed nucleic acid samples
#133Detecting nucleic acid
#134Crude biological derivatives competent for nucleic acid detection
#135Assay method for target nucleic acid by signal amplification using probe hybridization and restriction
#136METHODS FOR MANIPULATING BIOMOLECULES
#137Methods for generating databases and databases for identifying polymorphic genetic markers
#138Restriction endonuclease enhanced polymorphic sequence detection
#139Restriction enzyme based whole genome sequencing
#140Method for detecting microorganisms belonging to and/or
#141Linking sequence reads using paired code tags
#142Isothermal DNA amplification
#143GENOME ASSEMBLY
#144METHODS FOR MAKING TRANSCRIPTION PRODUCTS
#145Methods for sequencing nucleic acid molecules
#146Use of stem-loop oligonucleotides in the preparation of nucleic acid molecules
#147Methylation assay
#148Restriction endonuclease enhanced polymorphic sequence detection
#149Use of enzymes for altering ratios of partially matched polynucleotides
#150Assay methods using nicking endonucleases
#151SIZE SELECTION OF DNA FOR CHROMATIN ANALYSIS
#152DETECTION OF CHROMATIN STRUCTURE
#153Methods and compositions to detect and differentiate small RNAs in RNA maturation pathway
#154METHODS OF CATEGORIZING AN ORGANISM
#155Endonuclease-enhanced helicase-dependent amplification
#156Multiplex Nucleic Acid Detection
#157Methods for multiplexing recombinase polymerase amplification
#158Methods for Genotyping
#159TARGETED SEQUENCING LIBRARY PREPARATION BY GENOMIC DNA CIRCULARIZATION
#160Differential detection of single nucleotide polymorphisms
#161Polynucleotide mapping and sequencing
#162DETERMINATION OF CHROMATIN CONFORMATION
#163Multiplex amplification methods
#164IRE-1α substrates
#165Complexity management of genomic DNA
#166Gene synthesis by convergent assembly of oligonucleotide subsets
#167Method of amplifying a target nucleic acid by rolling circle amplification
#168METHODS FOR FLIP-STRAND IMMOBILIZING AND SEQUENCING NUCLEIC ACIDS
#169Generation of random double-strand breaks in DNA using enzymes
#170Analysis of single nucleotide polymorphisms using end labeling
#171Method for Estimating Telomere Length
#172ASSAY FOR LOCALIZED DETECTION OF ANALYTES
#173Methods for genotyping
#174Single molecule sequencing with two distinct chemistry steps
#175Repair of Nucleic Acids for Improved Amplification
#176METHODS FOR REMOVING NUCLEIC ACID CONTAMINATION FROM REAGENTS
#177Solid phase sequencing of biopolymers
#178DETECTION OF NUCLEIC ACIDS BY OLIGONUCLEOTIDE PROBES CLEAVED IN PRESENCE OF ENDONUCLEASE V
#179Methods and devices for single-molecule whole genome analysis
#180Composition for detection of RNA
#181Nucleic acid enzymes and complexes and methods for their use
#182REAL TIME POLYMERASE CHAIN REACTION PROCESS USING A UNIVERSAL DETECTION SYSTEM
#183COMPOSITIONS AND METHODS FOR TARGETED NUCLEIC ACID SEQUENCE SELECTION AND AMPLIFICATION
#184SELECTIVE RESTRICTION FRAGMENT AMPLIFICATION: FINGERPRINTING
#185Methods for repairing degraded DNA
#186Methods of characterizing small nucleic acid molecules
#187Methods for producing and using stem-loop oligonucleotides
#188Selective restriction fragment amplification: fingerprinting
#189DNA glycosylase/lyase and AP endonuclease substrates
#190Analysis of single nucleotide polymorphisms using a nicking endonuclease
#191Method of removing nucleic acid contamination in reverse transcription and amplification reactions
#192Methods and systems for measuring a property of a macromolecule
#193COMPOSITIONS AND METHODS FOR REVERSE TRANSCRIPTION OF NUCLEIC ACID MOLECULES
#194ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION
#195Detection of nucleic acid differences using combined endonuclease cleavage and ligation reactions
#196MEANS AND METHODS FOR DETECTION OF NUCLEIC ACIDS
#197Sequencing method
#198Method of oligonucleotide synthesis
#199Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
#200Methods for generating databases and databases for identifying polymorphic genetic markers
#201Complexity management of genomic DNA
#202T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
#203METHODS OF PREDICTING PAIRABILITY AND SECONDARY STRUCTURES OF RNA MOLECULES
#204SELECTIVE RESTRICTION FRAGMENT AMPLIFICATION: FINGERPRINTING
#205Method for treating a solution in order to destroy any ribonucleic acid after amplification
#206Isothermal strand displacement amplification using primers containing a non-regular base
#207Method for detection of mutant alleles combining real time PCR and REMS-PCR
#208Method for increasing efficiency or specificity of hybridization between PNA probes immobilized on support and target nucleic acids
#209Repair of Nucleic Acids for Improved Amplification
#210RNase H-based assays utilizing modified RNA monomers
#211DNA amplification and sequencing using DNA molecules generated by random fragmentation
#212QUALITATIVE DIFFERENTIAL SCREENING
#213Qualitative differential screening
#214Bio-driver apparatus for detecting a nucleic acid
#215Methods and compositions for ordering restriction fragments
#216Nucleic acid hybridization assay method
#217Method of Sequencing a Genome
#218Thermostable duplex-specific nuclease
#219Method for amplification of nucleotide sequence
#220Detecting nucleic acid
#221Methods of producing nucleic acid molecules comprising stem loop oligonucleotides
#222Method for methylation-selective amplification
#223Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen
#224Molecular beacon-based methods for detection of targets using abscription
#225Reverse transcription and amplification of RNA with simultaneous degradation of DNA
#226RNASE H-BASED ASSAYS UTILIZING MODIFIED RNA MONOMERS
#227Restriction endonuclease enhanced polymorphic sequence detection
#228PCR screening method
#229SYSTEM AND METHOD FOR DETECTING A GENE MUTATION
#230Methods for multiplexing recombinase polymerase amplification
#231Methods and Compositions for Amplification of DNA
#232COMPOSITIONS AND METHODS FOR REUSING ARRAYS
#233Methods and Assays for Capture of Nucleic Acids
#234Paired end sequencing
#235AUTONOMOUS IN VITRO EVOLUTION
#236System for the detection and enumeration of suspect target cells in a mixed cell population
#237METHODS OF IDENTIFYING AN ORGANISM FROM A HETEROGENEOUS SAMPLE
#238Method for the high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites
#239Use of Nucleic Acid Probes to Detect Nucleotide Sequences of Interest in a Sample
#240Method for Analysing Nucleic Acids
#241Nucleic acid detection combining amplification with fragmentation
#242ANTIBODY INHIBITING URACIL-DNA-GLYCOSYLASE AND USES THEREOF FOR DECONTAMINATING NUCLEIC ACID AMPLIFICATION REACTIONS
#243STRATEGIES FOR SEQUENCING COMPLEX GENOMES USING HIGH THROUGHPUT SEQUENCING TECHNOLOGIES
#244Use of dual-tags for the evaluation of genomic variable repeat regions
#245Methods for rapid forensic analysis of mitochondrial DNA
#246Detection of nucleic acid differences using endonuclease cleavage/ligase resealing reactions and capillary electrophoresis or microarrays
#247Methods for analyzing nucleic acid
#248Methods for detection of a target nucleic acid by forming a cleavage structure using an RNA polymerase
#249Method of amplifying a target nucleic acid by rolling circle amplification
#250Homogeneous luminescence bioassay
#251Method for identifying the sequence of one or more variant nucleotides in a nucleic acid molecule
#252Method for identifying the sequence of one or more variant nucleotides in a nucleic acid molecule
#253Dual Function Primers for Amplifying DNA and Methods of Use
#254Analytical Method and Kit
#255Accelerated cascade amplification (ACA) of nucleic acids comprising strand and sequence specific DNA nicking
#256Assays for measuring nucleic acid binding proteins and enzyme activities
#257Allele-specific copy number measurement using single nucleotide polymorphism and DNA arrays
#258Isothermal DNA amplification
#259COMPARATIVE SEQUENCE ANALYSIS PROCESSES AND SYSTEMS
#260APPARATUS, METHODS AND PRODUCTS FOR DETECTING GENETIC MUTATION
#261Compositions and Methods for Preventing Carry-Over Contamination in Nucleic Acid Amplification Reactions
#262Methods and compositions for the detection of a nucleic acid using a non-invasive cleavage reaction
#263Multiplex locus specific amplification
#2645'/3' Ratioing Procedure for Detection of Gene Rearrangements
#265Methods for using riboprimers for strand displacement replication of target sequences
#266Sequencing and genotyping using reversibly terminating nucleotides
#267Isothermal amplification of nucleic acids
#268Method and kit for detecting a target protein using a DNA aptamer
#269Assays for measuring nucleic acid binding proteins and enzyme activities
#270Assays for measuring nucleic acid binding proteins and enzyme activities
#271Circular DNA vectors for synthesis of RNA and DNA
#272Methods and Compositions for Detecting Target Sequences
#273Detection Of Nucleic Acids By Target-Catalyzed Product Formation
#274SYSTEMS AND METHODS FOR DETECTING NUCLEIC ACIDS
#275Methods and compositions for selectively cleaving DNA containing duplex nucleic acids in a complex nucleic acid mixture, and nuclease compositions for use in practicing the same
#276Methods for selective isolation of nucleic acids from microbial cells present in samples containing higher eukaryotic cells and/or tissues
#277Methods and Compositions for Detecting Target Sequences
#278Methods and compositions for selectively cleaving DNA containing duplex nucleic acids in a complex nucleic acid mixture, and nuclease compositions for use in practicing the same
#279T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
#280Methods and Compositions for Amplification of DNA
#281Cleavage of RNA at redundant sites
#282Methods and apparati using single polymer analysis
#283Reducing size of analytes in RNA sample
#284Methods for Rapid, Single-Step Strand Displacement Amplification of Nucleic Acids
#285Methods of detecting an amplified nucleic acid
#286Binary signal detection assays
#287Methods and Compositions for Amplification of DNA
#288Compositions and methods for the detection of a nucleic acid using a cleavage reaction
#289Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen
#290Methods of detecting a target nucleic acid
#291Compositions and methods for the detection of a nucleic acid using a cleavage reaction
#292Use Of A Type III Restriction Enzyme To Isolate Identification Tags Comprising More Than 25 Nucleotides
#293Detection of nucleic acid differences using combined endonuclease cleavage and ligation reactions
#294Procedure for the analysis of a sample
#295Compositions and methods for detection of a target nucleic acid sequence
#296Compositions and methods for detection of a target nucleic acid sequence
#297Methods of detection of a target nucleic acid sequence
#298Nucleic acid cleavage assays
#299Methods for quantitative cDNA analysis in single-cell
#300COMPOSITIONS AND METHODS FOR REVERSE TRANSCRIPTION OF NUCLEIC ACID MOLECULES