ClassID:

112760

C12Q2525/197 - CPC Classification

Classification description:

Reactions involving modified oligonucleotides, nucleic acids, or nucleotides; Modifications characterised by incorporating a spacer/coupling moiety

Recent Application in this class:
#1
20260125754
2026-05-07

HIGH INTENSITY LABELED REACTANT COMPOSITIONS AND METHODS FOR SEQUENCING

#2
20250362291
2025-11-27

ASSAY METHODS

#3
20250313901
2025-10-09

CIRCULATING MUTANT DNA TO ASSESS TUMOR DYNAMICS

#4
20250257389
2025-08-14

METHODS AND PROBES FOR PERFORMING PCR WITH MELT ANALYSIS FOR INCREASED MULTIPLEXING

#5
20250115899
2025-04-10

BISTABLE POLYNUCLEOTIDE DEVICES FOR THE SENSING AND QUANTIFICATION OF MOLECULAR EVENTS

#6
20240271199
2024-08-15

UNIVERSAL SHORT ADAPTERS WITH VARIABLE LENGTH NON-RANDOM UNIQUE MOLECULAR IDENTIFIERS

#7
20240209432
2024-06-27

POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION

#8
20240191285
2024-06-13

COMPOSITIONS, METHODS AND DEVICES COMPRISING STEM-LOOP CAPTOR MOLECULES

#9
20240124915
2024-04-18

METHODS FOR DELIVERING AN ANALYTE TO TRANSMEMBRANE PORES

#10
20240002948
2024-01-04

CIRCULATING MUTANT DNA TO ASSESS TUMOR DYNAMICS

#11
20230399681
2023-12-14

OLIGONUCLEOTIDE-FUNCTIONALIZED HYDROPHOBIC POLYMER NANOPARTICLES

#12
20230357821
2023-11-09

METHODS FOR DELIVERING AN ANALYTE TO TRANSMEMBRANE PORES

#13
20230242977
2023-08-03

Universal short adapters with variable length non-random unique molecular identifiers

#14
20220357318
2022-11-10

ASSAY METHODS

#15
20220282307
2022-09-08

Methods and probes for performing PCR with melt analysis for increased multiplexing

#16
20220195421
2022-06-23

Bistable polynucleotide devices for the sensing and quantification of molecular events

#17
20220090189
2022-03-24

Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection

#18
20210403978
2021-12-30

Methods for detecting agglutination and compositions for use in practicing the same

#19
20210147951
2021-05-20

In silico design of mammalian promoters with user-defined functionality

#20
20210147904
2021-05-20

Methods for delivering an analyte to transmembrane pores

#21
20210130875
2021-05-06

Oligonucleotide-functionalized hydrophobic polymer nanoparticles

#22
20210010061
2021-01-14

Method and apparatus to normalize quantitative readouts in single-cell experiments

#23
20210002696
2021-01-07

Method for amplifying target nucleic acid and composition for amplifying target nucleic acid

#24
20200370123
2020-11-26

CIRCULATING MUTANT DNA TO ASSESS TUMOR DYNAMICS

#25
20200354779
2020-11-12

Compositions, methods and devices comprising stem-loop captor molecules

#26
20200277665
2020-09-03

REVERSIBLE THERMODYNAMIC TRAP (THERMOTRAP) IN AMPLIFICATION OF NUCLEIC ACIDS

#27
20200172964
2020-06-04

Methods and probes for performing PCR with melt analysis for increased multiplexing

#28
20200087726
2020-03-19

ULTRA SENSITIVE PROBES FOR DETECTION OF NUCLEIC ACID

#29
20190391140
2019-12-26

Assay kits

#30
20190352327
2019-11-21

Compositions and methods for chemical cleavage and deprotection of surface-bound oligonucleotides

#31
20190323002
2019-10-24

Bistable polynucleotide devices for the sensing and quantification of molecular events

#32
20190093146
2019-03-28

Methods of identifying multiple epitopes in cells

#33
20190085384
2019-03-21

Universal short adapters with variable length non-random unique molecular identifiers

#34
20190062833
2019-02-28

Delaying real-time sequencing

#35
20190062807
2019-02-28

Substrates and methods useful in sequencing

#36
20190062805
2019-02-28

Methods of depleting a target molecule from an initial collection of nucleic acids, and compositions and kits for practicing the same

#37
20190024168
2019-01-24

High intensity labeled reactant compositions and methods for sequencing

#38
20190002968
2019-01-03

Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection

#39
20180363036
2018-12-20

Cooperative primers, probes, and applications thereof

#40
20180334729
2018-11-22

HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION

#41
20180267032
2018-09-20

Microarray having a base cleavable linker

#42
20180251830
2018-09-06

Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences

#43
20180244643
2018-08-30

HIGHLY SENSITIVE DETECTION OF BIOMOLECULES USING PROXIMITY INDUCED BIOORTHOGONAL REACTIONS

#44
20180216158
2018-08-02

Enhanced DNA sensing via catalytic aggregation of gold nanoparticles by DNA hybridization chain reaction

#45
20180171382
2018-06-21

BRANCHED PROXIMITY HYBRIDIZATION ASSAY

#46
20180112265
2018-04-26

Biochemically activated electronic device

#47
20180100181
2018-04-12

Methods for detecting agglutination and compositions for use in practicing the same

#48
20180087103
2018-03-29

HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION AND RELATED METHODS

#49
20180030520
2018-02-01

METHODS AND COMPOSITIONS FOR DETECTING TARGET NUCLEIC ACIDS

#50
20170342491
2017-11-30

Methods and compositions for nucleic acid amplification

#51
20170321273
2017-11-09

Methods and compositions for nucleic acid amplification

#52
20170275676
2017-09-28

Methods for analyzing nucleic acid

#53
20170253910
2017-09-07

Methods for delivering an analyte to transmembrane pores

#54
20170089892
2017-03-30

Assay methods

#55
20140295419
2014-10-02

Methods and compositions for isothermal whole genome amplification

#56
20140178878
2014-06-26

Oligonucleotides comprising a label associated through a linker

#57
20130005594
2013-01-03

Methods and compositions for detecting target nucleic acids

#58
20120329142
2012-12-27

Integrated nucleic acid assays

#59
20120295368
2012-11-22

KITS FOR DETECTING TARGET MATERIAL AND METHODS OF DETECTING TARGET MATERIAL USING THE KITS

#60
20120289419
2012-11-15

Methods and compositions for the target-localized anchoring of detectable label

#61
20120288857
2012-11-15

MULTIFUNCTIONAL PROBE-PRIMERS

#62
20120264630
2012-10-18

Method for detecting a circularized DNA, and use of said method for detecting mutations

#63
20120264122
2012-10-18

Methods and compositions for nucleic acid amplification

#64
20120208724
2012-08-16

Linking sequence reads using paired code tags

#65
20120135530
2012-05-31

Detection of target analytes using particles and electrodes

#66
20120108440
2012-05-03

Reducing adapter dimer formation

#67
20120095201
2012-04-19

Modified nucleotides

#68
20120088235
2012-04-12

HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION AND RELATED METHODS

#69
20120071330
2012-03-22

Multiplexed identification of nucleic acid sequences

#70
20120059147
2012-03-08

METHOD FOR SITE-SELECTIVELY CLEAVING TARGET NUCLEIC ACID

#71
20120004137
2012-01-05

IDENTIFICATION OF NUCLEIC ACID DELIVERY VEHICLES USING DNA DISPLAY

#72
20110294685
2011-12-01

Sensing strategies and methods for nucleic acid detection using biosensors

#73
20110275070
2011-11-10

Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders

#74
20110269646
2011-11-03

Sensing device and manufacturing method thereof

#75
20110251079
2011-10-13

High throughput nucleic acid sequencing by expansion

#76
20110237787
2011-09-29

High throughput nucleic acid sequencing by expansion

#77
20110236898
2011-09-29

Methods for enhancing nucleic acid hybridization

#78
20110218115
2011-09-08

Test probes, common oligonucleotide chips, nucleic acid detection method, and their uses

#79
20110160082
2011-06-30

Mobility-Modified Nucleobase Polymers and Methods of Using Same

#80
20110111975
2011-05-12

PROBE FOR NUCLEIC ACID SEQUENCING AND METHODS OF USE

#81
20110053788
2011-03-03

Detection of target analytes using particles and electrodes

#82
20110046350
2011-02-24

LENGTH-ADJUSTABLE NANOSCALE TETHER FOR BINDING TARGETS TO SUBSTRATES

#83
20110039264
2011-02-17

Format of probes to detect nucleic acid differences

#84
20110008787
2011-01-13

Detection primers for nucleic acid extension or amplification reactions

#85
20100317004
2010-12-16

PROBES

#86
20100292452
2010-11-18

Modified nucleotides

#87
20100279882
2010-11-04

SEQUENCING METHODS

#88
20100267169
2010-10-21

Electromagnetic molecular sensors and methods of using same

#89
20100248991
2010-09-30

Solid support for high-throughput nucleic acid analysis

#90
20100248237
2010-09-30

MINIATURIZED, HIGH-THROUGHPUT NUCLEIC ACID ANALYSIS

#91
20100227913
2010-09-09

Nanoprobes for detection or modification of molecules

#92
20100227329
2010-09-09

Method for introducing a sample specific DNA tag into a plurality of DNA fragments from a plurality of samples

#93
20100203541
2010-08-12

Nucleotide analogs

#94
20100197041
2010-08-05

NUCLEIC ACID BINDING ASSAYS

#95
20100197032
2010-08-05

Nanoassembled complexes of nucleic acids, avidin and polymers, use and preparation thereof

#96
20100184022
2010-07-22

Hybridization Probe Assay and Array

#97
20100151464
2010-06-17

Compositions and methods for preparing oligonucleotide solutions

#98
20100129819
2010-05-27

Methods and compositions in particle-based detection of target molecules using linking molecules

#99
20100099858
2010-04-22

Maximizing Oligonucleotide Loading on Gold Nanoparticle

#100
20100087329
2010-04-08

Enzymatic labeling of RNA

#101
20100041048
2010-02-18

Circulating Mutant DNA to Assess Tumor Dynamics

#102
20100029494
2010-02-04

Macromolecular nucleotide compounds and methods for using the same

#103
20100028885
2010-02-04

Labelled nucleotides

#104
20090325812
2009-12-31

Nanoparticles having oligonucleotides attached thereto and uses therefor

#105
20090325172
2009-12-31

Modified nucleotides

#106
20090280998
2009-11-12

Microarray having a base cleavable linker

#107
20090269759
2009-10-29

Unnatural polymerase substrates that can sustain enzymatic synthesis of double stranded nucleic acids from a nucleic acid template and methods of use

#108
20090221435
2009-09-03

MICROARRAY FOR DETECTING AND QUANTIFYING MICRORNA

#109
20090215032
2009-08-27

Analyte detection using barcoded polymers

#110
20090163366
2009-06-25

TWO-PRIMER SEQUENCING FOR HIGH-THROUGHPUT EXPRESSION ANALYSIS

#111
20090148933
2009-06-11

Integrated nucleic acid assays

#112
20090148847
2009-06-11

RAPID MAGNETIC FLOW ASSAYS

#113
20090099039
2009-04-16

BINARY-COUPLED PROBE ARRAY, BIOCHIP, AND METHOD OF FABRICATION

#114
20090078574
2009-03-26

Charge tags and the separation of nucleic acid molecules

#115
20090075275
2009-03-19

NUCLEIC ACID PROBE-IMMOBILIZED SUBSTRATE AND METHOD OF DETECTING THE PRESENCE OF TARGET NUCLEIC ACID BY USING THE SAME

#116
20090061435
2009-03-05

Methods and compositions for rapid amplification, capture and detection of nucleic acids and proteins

#117
20090048427
2009-02-19

Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders

#118
20090035777
2009-02-05

High throughput nucleic acid sequencing by expansion

#119
20090023150
2009-01-22

DNA Diagnostics Based on Mass Spectrometry

#120
20080305482
2008-12-11

Methods and compositions for nucleic acid amplification

#121
20080299565
2008-12-04

Probe for nucleic acid sequencing and methods of use

#122
20080293930
2008-11-27

3′ end tagged oligonucleotides

#123
20080286837
2008-11-20

Nucleotide analogs

#124
20080254548
2008-10-16

Detection of target analytes using particles and electrodes

#125
20080248592
2008-10-09

Detection of target analytes using particles and electrodes

#126
20080131880
2008-06-05

PNA-DNA oligomers and methods of use thereof

#127
20080125327
2008-05-29

RNA sequences generated using a microarray having a base cleavable succinate linker

#128
20080090238
2008-04-17

Increased sensitivity of proximity ligation assays

#129
20080081330
2008-04-03

Method and devices for analyzing small RNA molecules

#130
20080076131
2008-03-27

Methods and devices for nucleic acid amplification on a surface

#131
20080026382
2008-01-31

Enzymatic labeling of RNA

#132
20070269799
2007-11-22

Nucleic acid amplification methods

#133
20070259347
2007-11-08

Methods of increasing the effective probe densities of arrays

#134
20070259345
2007-11-08

Target determination using compound probes

#135
20070259344
2007-11-08

Compound probes and methods of increasing the effective probe densities of arrays

#136
20070238101
2007-10-11

Nucleic acid interaction analysis

#137
20070224605
2007-09-27

Method for preparing a DNA chip and use thereof

#138
20070202514
2007-08-30

DNA diagnostics based on mass spectrometry

#139
20070178519
2007-08-02

Length determination of nucleic acid repeat sequences by discontinuous primer extension

#140
20070166705
2007-07-19

Modified nucleotides

#141
20070148639
2007-06-28

Methods and devices for nucleic acid amplification on a surface

#142
20070128643
2007-06-07

Method for assaying nucleic acid fragment and kit thereof

#143
20070077582
2007-04-05

Method for quantitative detection of short RNA molecules

#144
20070065877
2007-03-22

Microarray having a base cleavable succinate linker

#145
20070059732
2007-03-15

Detection of target analytes using particles and electrodes

#146
20070026434
2007-02-01

Mobility-modified nucleobase polymers and methods of using same

#147
20070003957
2007-01-04

Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis

#148
20060292586
2006-12-28

ID-tag complexes, arrays, and methods of use thereof

#149
20060275787
2006-12-07

Compositions and methods for array-based genomic nucleic acid analysis of biological molecules

#150
20060269916
2006-11-30

Probes

#151
20060194240
2006-08-31

Compositions and methods of detecting an analyte by using a nucleic acid hybridization switch probe

#152
20060188901
2006-08-24

Labelled nucleotides

#153
20060177826
2006-08-10

Method of producing recombinant DNA molecules

#154
20060160075
2006-07-20

Labelled nucleotides

#155
20060147940
2006-07-06

Combinatorial affinity selection

#156
20060141523
2006-06-29

Integrated method for PCR cleanup and oligonucleotide removal

#157
20060105351
2006-05-18

Method and system for nucleic acid detection

#158
20060068378
2006-03-30

Nanoparticles having oligonucleotides attached thereto and uses therefor

#159
20060051798
2006-03-09

Bio-barcodes based on oligonucleotide-modified particles

#160
20060008813
2006-01-12

Compositions and methods of synthesis and use of novel nucleic acid structures

#161
20060003366
2006-01-05

Multiplexing assays for analyte detection

#162
20050233358
2005-10-20

Electrochemical detection of nucleic acid hybridization

#163
20050221362
2005-10-06

Method for immobilizing nucleic acid and method for manufacturing biosensor using the same method

#164
20050214825
2005-09-29

Multiplex sample analysis on universal arrays

#165
20050196786
2005-09-08

Multiplex spatial profiling of gene expression

#166
20050176023
2005-08-11

Self-hybridizing multiple target nucleic acid probes and methods of use

#167
20050130216
2005-06-16

Molecular torches and their use under strand displacement conditions

#168
20050130179
2005-06-16

Charge tags and the separation of nucleic acid molecules

#169
20050123988
2005-06-09

Molecular torches and their use under denaturing conditions

#170
20050112671
2005-05-26

FRET efficiency methods

#171
20050112619
2005-05-26

Length determination of nucleic acid repeat sequences by discontinuous primer extension

#172
20050112609
2005-05-26

Method for distinguishing different-sequence polynucleotides

#173
20050112608
2005-05-26

Method for distinguishing different-sequence polynucleotides

#174
20050112591
2005-05-26

Novel method for isolating single stranded product

#175
20050064494
2005-03-24

Chemically modified biological molecules and methods for coupling biological molecules to solid support

#176
20050064463
2005-03-24

Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders

#177
20050053979
2005-03-10

Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same

#178
20050042644
2005-02-24

Mobility-modified nucleobase polymers and methods of using same

#179
20050042638
2005-02-24

Oligonucleotides comprising a molecular switch