114207 ⎘
Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12) Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
SPLIT RIBOZYME BIOSENSOR SYSTEMS
#2AGENT FOR DETECTING STRUCTURALLY ABNORMAL PROTEIN AND AGENT FOR REDUCING STRUCTURALLY ABNORMAL PROTEIN
#3OPLOPHORUS-DERIVED LUCIFERASES, NOVEL COELENTERAZINE SUBSTRATES, AND METHODS OF USE
#4INDUCIBLE PROMOTER, VECTOR AND HOST CELL BASED THEREON
#5NOVEL LUCIFERASES WITH IMPROVED PROPERTIES
#6BLOCK COPOLYMERS
#7DE NOVO DESIGNED LUCIFERASE
#8MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF ONCOLOGY-RELATED PROTEINS AND PEPTIDES
#9MUTANTS AND USE THEREOF
#10MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE
#11MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS
#12COMPLEMENTATION-BASED TAGS AND REPORTERS FOR DUAL-MODALITY LABELING
#13MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE
#14BLOCK COPOLYMERS
#15TUMOR-TARGETING SYNTHETIC ADENOVIRUSES AND USES THEREOF
#16AGENTS FOR MANUFACTURE OF CO-ASSEMBLING PEPTIDES
#17OPLOPHORUS-DERIVED LUCIFERASES, NOVEL COELENTERAZINE SUBSTRATES, AND METHODS OF USE
#18ENZYMES OF LUCIFERIN BIOSYNTHESIS AND USE THEREOF
#19NOVEL LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS
#20ALTERNATIVE NUCLEIC ACID MOLECULES CONTAINING REDUCED URACIL CONTENT AND USES THEREOF
#21DETECTION OF ENVIRONMENTAL INFLUENCES BY BIOLUMINESCENCE
#22LIPID NANOPARTICLE FORMULATIONS
#23SYNTHETIC ADENOVIRUSES TARGETING BONE TISSUE AND USES THEREOF
#24Luciferase-based thermal shift assays
#25ISOLATED NUCLEIC ACID MOLECULE AND APPLICATION THEREOF
#26DETECTION ASSAY FOR ANTI-SARS-COV-2 ANTIBODIES
#27NON-REPLICATIVE TRANSDUCTION PARTICLES WITH ONE OR MORE NON-NATIVE TAIL FIBERS AND TRANSDUCTION PARTICLE-BASED REPORTER SYSTEMS
#28AUTO-INDUCTION REGULATORY SYSTEM BASED ON QUORUM SENSING AND APPLICATION THEREOF
#29Synthetic luciferases with enhanced light output
#30DNA VACCINES
#31Quantitative assessment for cap efficiency of messenger RNA
#32Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
#33Methods and Compositions for Selecting siRNA of Improved Functionality
#34Polypeptide having luciferase activity
#35NOVEL LUCIFERASE SEQUENCES UTILIZING INFRARED-EMITTING SUBSTRATES TO PRODUCE ENHANCED LUMINESCENCE
#36Lipids and lipid nanoparticle formulations for delivery of nucleic acids
#37LUCIFERASE VARIANT
#38Method for visually enhancing the experience of an audience during a performance
#39MONOCLONAL ANTIBODY FUSIONS
#40MODIFIED RNA WITH DECREASED IMMUNOSTIMULATORY PROPERTIES
#41LUCIFERASE VARIANT
#42ENZYMES OF LUCIFERIN BIOSYNTHESIS AND USE THEREOF
#43MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE
#44Luciferase-based thermal shift assays
#45METHODS OF IMMUNOSTIMULATION WITH COMPLEXES OF RNA AND CATIONIC CARRIERS
#46Lipid-derived neutral nanoparticles
#47Block copolymers
#48Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
#49Complex BRET technique for measuring biological interactions
#50Method for inhibiting the expression of cancer-promoting factors
#51MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS
#52Carbohydrate sensors
#53Methods and compositions for selecting siRNA of improved functionality
#54MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF ONCOLOGY-RELATED PROTEINS AND PEPTIDES
#55KDAC VARIANTS AND USES THEREOF
#56Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems
#57Wash monitor and method of use
#58Luciferase-based thermal shift assays
#59Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
#60Lipid nanoparticle formulations
#61Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence
#62METHODS OF ATTACHING A MOLECULE-OF-INTEREST TO A MICROTUBE
#63METHOD OF ATTACHING A CELL-OF-INTEREST TO A MICROTUBE
#64THIENOPYRROLE COMPOUNDS AND USES THEREOF
#65Mutated genes for the catalytic protein of oplophorus luciferase and use thereof
#66Stable VAMP reporter assay
#67Bioluminescent assays utilising secreted luciferases
#68METHODS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS WITH ENHANCED PHARMACOLOGICAL PROPERTIES
#69Heat-resistant luciferase
#70Modified polynucleotides for the production of secreted proteins
#71Nucleic acid constructs and methods of using the same
#72Mutant beetle luciferase, gene, recombinant vector, transformant, and method for preparing mutant beetle luciferase
#73Methods and Compositions for Selecting siRNA of Improved Functionality
#74Reagent cartridge for detection of cells
#75Methods and Compositions for Selecting siRNA of Improved Functionality
#76Modified polynucleotides for the production of secreted proteins
#77In vivo production of proteins
#78SYNTHETIC ADENOVIRUSES TARGETING BONE TISSUE AND USES THEREOF
#79Lipids and lipid nanoparticle formulations for delivery of nucleic acids
#80Tumor-targeting synthetic adenoviruses and uses thereof
#81Thermal stable luciferase with improved resistance to inhibition by luciferin break-down products
#82Cell-based assay for determining mTOR activity
#83Reporter construct and biosensor for interferon second messenger 2-5A
#84Method for visually enhancing the experience of an audience during a performance
#85Targeted effector proteins and uses thereof
#86Method for increasing expression of RNA-encoded proteins
#87DNA vaccines
#88Chemiluminescent wetness indicator for absorbent products
#89Lipid-derived neutral nanoparticles
#90METHODS OF TREATING A SUBJECT HAVING GLYCOGEN STORAGE DISEASE WITH mRNA ENCODING GLUCOSE-6-PHOSPHATASE CATALYTIC SUBUNIT (G6PC)
#91METHODS OF TREATING A SUBJECT HAVING PROPIONIC ACIDEMIA WITH mRNA ENCODING PROPIONYL-COA CARBOXYLASE, SUBUNIT ALPHA AND/OR BETA (PCCA AND/OR PCCB)
#92METHODS OF TREATING A SUBJECT HAVING CITRULLINEMIA WITH mRNA ENCODING ARGININOSUCCINATE SYNTHASE (ASS)
#93METHODS OF TREATING A SUBJECT HAVING FRIEDREICH'S ATAXIA WITH mRNA ENCODING FRATAXIN
#94METHODS OF TREATING A SUBJECT HAVING GLYCOGEN STORAGE DISEASE II WITH mRNA ENCODING ACID GLUCOSIDASE ALPHA (GAA)
#95METHODS OF TREATING A SUBJECT WITH mRNA ENCODING COAGULATION FACTOR VIII (F8)
#96METHODS OF TREATING PHENYLKETONURIA WITH MRNA ENCODING PHENYLALANINE HYDROXYLASE (PAH)
#97Recombinant polynucleotide coding for polypeptide comprising reporter moiety, substrate moiety and destabilizing moiety, host cell comprising same and use of same
#98Method for synthetic genes
#99Nucleic acid encoding a luminescent enzyme protein
#100ALTERNATIVE NUCLEIC ACID MOLECULES CONTAINING REDUCED URACIL CONTENT AND USES THEREOF
#101Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
#102Methods and Compositions for Selecting siRNA of Improved Functionality
#103NANOBIONIC LIGHT EMITTING PLANTS
#104Modified Polynucleotides for the production of biologics and proteins associated with human disease
#105COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#106Quantitative assessment for cap efficiency of messenger RNA
#107Block copolymers
#108COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#109Functionalized NANOLUC inhibitors
#110Mutated genes for the catalytic protein of oplophorus luciferase and use thereof
#111Methods and compositions for selecting siRNA of improved functionality
#112Methods and compositions for selecting siRNA of improved functionality
#113Method for synthetic genes
#114MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS
#115COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#116COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#117Lipid-derived neutral nanoparticles
#118Lipid-derived neutral nanoparticles
#119Cell-based assay for determining mTOR activity
#120COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#121COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#122COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#123COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#124COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#125Methods and compositions for selecting siRNA of improved functionality
#126COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#127MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE
#128Red-shifted luciferase-luciferin pairs for enhanced bioluminescence
#129Alternative nucleic acid molecules containing reduced uracil content and uses thereof
#130Modified polynucleotides for the production of oncology-related proteins and peptides
#131Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
#132Methods and Compositions for Selecting siRNA of Improved Functionality
#133In vivo production of proteins
#134Luciferin-containing substrate and monitoring device including the substrate
#135Modified Luciferases And Uses Thereof
#136Non-replicative transduction particles and transduction particle-based reporter systems
#137Non-replicative transduction particles and transduction particle-based reporter systems
#138Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence
#139METHOD FOR PURIFYING PROTEIN
#140Methods for establishing animal model of hepatocellular carcinoma bone metastasis
#141GENETIC DETECTION PLATFORM
#142Biosensor based on Gβγ-interacting proteins to monitor G-protein activation
#143Substituted benzo[f]imidazo[1,2-a]quinoxalines
#144Bioluminescent assays utilising secreted luciferases
#145Blue light-inducible system for gene expression
#146Luciferase showing orange luminescence
#147Non-replicative transduction particles and transduction particle-based reporter systems
#148Two-dimensional fluorescence difference spectroscopy characterization of nanoparticles and their interactions
#149Recombinant RSV reporter virus
#150COELENTERAZINE ANALOGS
#151ENZYMATIC SYNTHESIS OF POLY(AMINE-CO-ESTERS) AND METHODS OF USE THEREOF FOR GENE DELIVERY
#152Mutated genes for the catalytic protein of oplophorus luciferase and use thereof
#153Antibacterial and plasmid elimination agents
#154Reagent cartridge for detection of cells
#155COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES
#156MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS
#157Treatment of proliferative disorders with a chemiluminescent agent
#158METHODS OF ATTACHING A MOLECULE-OF-INTEREST TO A MICROTUBE
#159Red-shifted luciferins and methods of using same
#160Thienopyrrole compounds and uses thereof
#161Cyan-excitable orange-red fluorescent proteins and bioluminescent resonance energy transfer systems
#162Modified polynucleotides for the production of secreted proteins
#163COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#164Mutated genes for the catalytic protein of and use thereof
#165Permuted and nonpermuted luciferase biosensors
#166WASH MONITOR AND METHOD OF USE
#167Luciferase-based thermal shift assays
#168Non-replicative transduction particles and transduction particle-based reporter systems
#169Non-replicative transduction particles and transduction particle-based reporter systems
#170Luminescent substrate for use in artificial bioluminescent enzyme
#171Modified luciferases and uses thereof
#172Mutated genes for the catalytic protein of oplophorus luciferase and use thereof
#173Alternative nucleic acid molecules containing reduced uracil content and uses thereof
#174Modified RNA with decreased immunostimulatory properties
#175SCREENING FOR NITROGEN FIXATION
#176Block copolymers
#177Methods and compositions for selecting siRNA of improved functionality
#178Methods and compositions for selecting siRNA of improved functionality
#179Designed peptides for tight junction barrier modulation
#180Methods and compositions for selecting siRNA of improved functionality
#181Methods and compositions for selecting siRNA of improved functionality
#182Method for increasing expression of RNA-encoded proteins
#183Mutant protease biosensors with enhanced detection characteristics
#184Methods and compositions for delivering active agents with enhanced pharmacological properties
#185Chemiluminescent wetness indicator for absorbent products
#186Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence
#187Method for synthetic genes
#188Modified polynucleotides for the production of biologics and proteins associated with human disease
#189Quantitative assessment for cap efficiency of messenger RNA
#190Substituted imidazo[1,2-a]pyrazines for use in bioluminogenic methods
#191Modified polynucleotides for the production of secreted proteins
#192PRODUCTION OF CLOSED LINEAR DNA
#193Method of treating cancer using high efficiency self-illuminative nanocomplexes and method of manufacturing the same
#194Firefly luciferase
#195Artificial bioluminescent enzyme
#196Chimeric genes for the catalytic protein of luciferase and use thereof
#197Wash monitor and method of use
#198Isolated luciferases and the use thereof
#199Substituted benzo[f]imidazo[1,2-a]quinoxalines and imidazo[1,2-a]pyrazines
#200Mutated genes for the catalytic protein of oplophorus luciferase and use thereof
#201CHIMERIC LUCIFERASES
#202Optogenetic inhibition of overactive neuronal activity
#203Mutated genes for the catalytic protein of luciferase and use thereof
#204Process for production of recombinant proteins as a soluble form
#205Lipid-derived neutral nanoparticles
#206Imidazo[1,2-a]pyrazine derivatives
#207Compositions, systems, and methods for detecting a DNA sequence
#208COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES
#209MOLECULAR AND CELLULAR IMAGING USING ENGINEERED HEMODYNAMIC RESPONSES
#210Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
#211Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
#212Mutant luciferases
#213Methods and compositions for selecting siRNA of improved functionality
#214Complexes of RNA and cationic peptides for transfection and for immunostimulation
#215Treatment of proliferative disorders with a chemiluminescent agent
#216Biological systems input-output response system and plant sentinels
#217Mutant firefly luciferase, its gene and method for producing mutant firefly luciferase
#218Production of closed linear DNA
#219Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
#220COMPOSITIONS CONTAINING INCLUSION COMPLEXES
#221Multiplex assays with multiple luciferases reporters and uses thereof
#222siRNA targeting spleen tyrosine kinase
#223Imidazo[1,2-α]pyrazine derivatives
#224METHODS AND COMPOSITIONS FOR SELECTING SIRNA OF IMPROVED FUNCTIONALITY
#225METHOD FOR AMPLIFYING ADENOSINE TRIPHOSPHATE AND METHOD AND REAGENT FOR DETECTING THE CONCENTRATION OF MICROORGANISMS
#226Modified luciferase gene and protein
#227siRNA targeting cyclin-dependent kinase 4 (CDK4)
#228Mutant protease biosensors with enhanced detection characteristics
#229Complexing agents for compositions containing inclusion complexes
#230Compositions containing inclusion complexes
#231Isolated luciferase gene of
#232siRNA targeting spleen tyrosine kinase
#233Methods of attaching a molecule-of-interest to a microtube
#234Method of attaching a cell-of-interest to a microtube
#235Permuted and nonpermuted luciferase biosensors
#236Use of electrospun microtubes for drug delivery
#237siRNA Targeting Survivin
#238siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)
#239Methods and compositions for selecting siRNA of improved functionality
#240siRNA targeting KRAS
#241COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
#242Isolated luciferases and the use thereof
#243siRNA targeting BCL2L1
#244Bioluminescent assays utilising secreted luciferases
#245siRNA targeting spleen tyrosine kinase
#246siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)
#247siRNA targeting survivin
#248siRNA targeting myeloid cell Leukemia sequence 1
#249Mutant firefly luciferase, gene, recombinant vector, transformant, and method for production of mutant firefly luciferase
#250siRNA targeting KRAS
#251siRNA targeting transducin (beta)-like 3 (TBL3)
#252siRNA targeting cyclin-dependent kinase 4 (CDK4)
#253siRNA targeting myeloid cell leukemia sequence 1
#254siRNA targeting tumor necrosis factor receptor superfamily member 1A
#255SiRNA targeting KRAS
#256Antibacterial and plasmid elimination agents
#257Biological systems input-output response system and plant sentinels
#258siRNA targeting transducin (beta)-like 3 (TBL3)
#259siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)
#260siRNA targeting proprotein convertase subtilisin/kexin type 9 (PCSK9)
#261siRNA targeting vascular endothelial growth factor receptor 1 (VEGFR1)
#262siRNA targeting protein tyrosine phosphatase-1B (PTP1B)
#263siRNA targeting casitas B cell lymphoma-B (CBL-B)
#264siRNA targeting cystic fibrosis transmembrane conductance regulator (CFTR)
#265siRNA targeting human hairless protein (HR)
#266siRNA targeting DNA-damage-inducible transcript 4 (DDIT4)
#267siRNA targeting myeloid cell leukemia sequence 1
#268Functional and hyperfunctional siRNA directed against Bcl-2
#269Functional and hyperfunctional siRNA directed against Bcl-2
#270Functional and hyperfunctional siRNA directed against Bcl-2
#271Functional and hyperfunctional siRNA directed against Bcl-2
#272Functional and hyperfunctional siRNA directed against Bcl-2
#273Functional and hyperfunctional siRNA directed against Bcl-2
#274Functional and hyperfunctional siRNA directed against Bcl-2
#275Functional and hyperfunctional siRNA directed against Bcl-2
#276Process for production of recombinant proteins as a soluble form
#277Lipid-Mediated Polynucleotide Administration to Deliver a Biologically Active Peptide and to Induce a Cellular Immune Response
#278Functional and hyperfunctional siRNA
#279Isolated luciferase gene of
#280Split protein self complementing fragments, systems, and methods of use thereof
#281siRNA targeting spleen tyrosine kinase
#282Complexing agents for compositions containing inclusion complexes
#283siRNA targeting carbonic anhydrase II
#284siRNA targeting MCL1
#285siRNA targeting tumor necrosis factor superfamily member 1A
#286siRNA targeting complement factor B
#287siRNA targeting BCL2L1
#288siRNA targeting KRAS
#289siRNA targeting survivin
#290Functional and hyperfunctional siRNA
#291Functional and hyperfunctional siRNA
#292Optical imaging based on locally activated bioluminescence
#293Compositions containing inclusion complexes
#294Dilation introducer for orthopedic surgery
#295Methods and compositions for selecting siRNA of improved functionality
#296Functional and hyperfunctional siRNA
#297Functional and hyperfunctional siRNA directed against Bcl-2
#298TelA variants, compositions, and methods