116520 ⎘
Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2); Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1) Alpha-galactosidase (3.2.1.22)
A METHOD FOR ENHANCING THE FLAVOR AND/OR THE TEXTURE OF A PLANT-BASED PRODUCT
#2ALPHA-GALACTOSIDASE PROTEIN FOR ENZYME REPLACEMENT THERAPY (ERT) AND METHODS OF USE
#3COMPOUNDS, DEVICES, AND USES THEREOF
#4STABILIZED ALPHA-GALACTOSIDASE AND USES THEREOF
#5OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF
#6ICAM-1 TARGETED FUSION ENZYMES
#7Disulfide Bond Stabilized Polypeptide Compositions And Methods Of Use
#8HUMAN ALPHA-GALACTOSIDASE VARIANTS
#9COMPOSITIONS AND METHODS FOR INTERNALIZING ENZYMES
#10NOVEL IN VITRO AND IN VIVO ENRICHMENT STRATEGY TARGETING LYMPHOCYTES DERIVED FROM VECTOR TRANSDUCED HSCS FOR THERAPY OF DISORDERS
#11HUMAN ALPHA-GALACTOSIDASE VARIANTS
#12USE OF LENTIVECTOR-TRANSDUCED T-RAPA CELLS FOR AMELIORATION OF LYSOSOMAL STORAGE DISORDERS
#13ADENO-ASSOCIATED VIRUS VARIANT CAPSIDS AND METHODS OF USE THEREOF
#14Lyophilized Pharmaceutical Compositions Comprising A Lipid Nanoparticle
#15LIQUID FORMULATION COMPRISING A FUSION PROTEIN INCLUDING a-GALACTOSIDASE A
#16Lipid Nanoparticle Compositions and Methods for mRNA Delivery
#17METHODS FOR USE OF VIRAL VECTOR CONSTRUCTS FOR THE TREATMENT OF FABRY DISEASE
#18COMPOSITIONS AND METHODS OF USING TWO-PROMOTER VECTOR FOR TREATMENT OF LYSOSOMAL STORAGE DISORDERS
#19THERAPEUTIC REGIMEN FOR THE TREATMENT OF FABRY USING STABILIZED ALPHA-GALACTOSIDASE
#20BIOMARKERS OF METHOTREXATE-INDUCED IMMUNE TOLERANCE
#21Lipid Nanoparticle Compositions and Methods for mRNA Delivery
#22LYOPHILIZED FORMULATION COMPRISING A FUSION PROTEIN INCLUDING a-GALACTOSIDASE A
#23TARGETED DELIVERY OF MODIFIED RNA
#24RECOMBINANT AAV FOR THE GENE THERAPY OF FABRY DISEASE
#25Human alpha-galactosidase variants
#26COMPOSITION COMPRISING GALACTINOL AND USE THEREOF
#27Integrated Continuous Manufacturing of Therapeutic Protein Drug Substances
#28COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE
#29Lyophilized Pharmaceutical Compositions Comprising a Lipid Nanoparticle
#30Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders
#31ENGINEERED ALPHA-GALACTOSIDASE A (A-GAL A) PEPTIDES AND FUNCTIONAL VARIANTS THEREOF AND ASSOCIATED METHODS OF TREATING FABRY DISEASE
#32DIGITAL MICROBIOLOGY
#33ICAM-1 targeted fusion enzymes
#34Compositions and Methods for Treating Fabry Disease
#35COMPOUNDS, DEVICES, AND USES THEREOF
#36COMPOSITIONS AND METHODS FOR INCREASING EXTRACTIBILITY OF SOLIDS FROM COFFEE BEANS
#37SITE-SPECIFIC GLYCAN REMODELING OF LYSOSOMAL ENZYMES AND APPLICATIONS THEREOF
#38GENETICALLY MODIFIED HUMAN CELL LINES AND USES THEREOF
#39COMPOSITION AND METHODS FOR THE TREATMENT OF FABRY DISEASE
#40LIPOSOMES AND ITS USE FOR ENZYME DELIVERY
#41Method and special complex enzyme for hydrolyzing galactomannan (GM) to prepare small-molecule GM and galactomannan oligosaccharide (GMOS)
#42METHOD FOR OBTAINING MATERIAL FROM PLANT CELL SURFACES
#43CODON OPTIMIZED GLA GENES AND USES THEREOF
#44ASSAYS FOR FABRY DISEASE TREATMENT
#45LYSOSOMAL ENZYMES MODIFIED BY CELL BASED GLYCOENGINEERING
#46USE OF THERAPEUTIC ENZYME FUSION PROTEIN IN PREVENTION AND TREATMENT OF RENAL DISEASES CAUSED BY OR ACCOMPANIED BY FABRY DISEASE
#47COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE
#48AFFINITY PURIFICATION OF GLYCOSIDE-CLEAVING ENZYMES
#49Yeast promotors for protein expression
#50Novel In Vitro and In Vivo Enrichment Strategy Targeting Lymphocytes Derived from Vector Transduced HSCS for Therapy of Disorders
#51Lipid nanoparticle compositions and methods for mRNA delivery
#52POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE
#53LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY
#54Lipid nanoparticle compositions and methods for MRNA delivery
#55Lipid nanoparticle compositions and methods for MRNA delivery
#56Methods and compositions for the treatment of steatosis-associated disorders
#57Methods and Compositions for the Treatment of Steatosis-Associated Disorders
#58Adeno-associated virus variant capsids and methods of use thereof
#59Codon optimized GLA genes and uses thereof
#60ANIMAL FEED COMPOSITIONS
#61Recombinant Alpha-Galactosidase A For Treatment Of Fabry Disease
#62STABILIZED ALPHA-GALACTOSIDASE AND USES THEREOF
#63Glycosylated lysosomal proteins, method of production and uses
#64Lipid nanoparticle compositions and methods for mRNA delivery
#65LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY
#66Human alpha-galactosidase variants
#67Improved Alpha-Galactosidase Protein for Enzyme Replacement Therapy (ERT) and Methods of Use
#68A GENETICALLY MODIFIED FUNGUS AND METHODS AND USES RELATED THERETO
#69METHODS AND COMPOSITIONS FOR THE TREATMENT OF FABRY DISEASE
#70Adeno-associated virus variant capsids and methods of use thereof
#71OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF
#72ICAM-1 targeted fusion enzymes
#73Cleavable lipids
#74Digital microbiology
#75Modified recombinant lysosomal alpha-galactosidase A and aspartylglucoaminidase having low mannose-6-phosphate and high sialic acid
#76NOVEL ALPHA-GALACTOSIDASE A DERIVATIVES
#77Lipid nanoparticle compositions and methods for mRNA delivery
#78LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY
#79Lipid nanoparticle compositions and methods for MRNA delivery
#80Lipid nanoparticle compositions and methods for mRNA delivery
#81SUBCUTANEOUS THERAPEUTIC ENZYME FORMULATIONS, USES, AND METHODS FOR GENERATING THEREOF
#82RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR FOR GENE DELIVERY
#83Recombinant Glycoproteins and Uses Thereof
#84Decellularization of Plant Cell Culture Materials for Tissue Engineering and Drug Delivery
#85mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES
#86Lipid nanoparticle compositions and methods for mRNA delivery
#87Methods and compositions for the treatment of cytoplasmic glycogen storage disorders
#88Disulfide bond stabilized polypeptide compositions and methods of use
#89Adeno-associated virus variant capsids and methods of use thereof
#90Codon optimized GLA genes and uses thereof
#91Use of lentivector-transduced T-Rapa cells for amelioration of lysosomal storage disorders
#92Lipid nanoparticle compositions and methods for mRNA delivery
#93Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
#94HUMAN ALPHA-GALACTOSIDASE VARIANTS
#95GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
#96Methods and compositions for the treatment of steatosis-associated disorders
#97Human alpha-galactosidase variants
#98COMPOSITIONS AND METHODS FOR INCREASING EXTRACTABILITY OF SOLIDS FROM COFFEE BEANS
#99ICAM-1 targeted fusion enzymes
#100Lipid nanoparticle compositions and methods for mRNA delivery
#101Affinity purification of glycosidase-cleaving enzymes
#102Yeast promotors for protein expression
#103ANIMAL CELL STRAIN AND METHOD FOR USE IN PRODUCING GLYCOPROTEIN, GLYCOPROTEIN AND USE THEREOF
#104THERAPEUTIC ENZYME FUSION PROTEIN HAVING A NOVEL STRUCTURE AND USE THEREOF
#105Biomarkers of methotrexate-induced immune tolerance
#106Human alpha-galactosidase variants
#107Polypeptides Having Alpha-Galactosidase Activity and Polynucleotides Encoding Same
#108Polypeptides Having Alpha-Galactosidase Activity and Polynucleotides Encoding Same
#109Sterile chromatography and manufacturing processes
#110Human alpha-galactosidase variants
#111Human alpha-galactosidase variants
#112Lipid nanoparticle compositions and methods for mRNA delivery
#113Integrated continuous manufacturing of therapeutic protein drug substances
#114Enzyme exhibiting fructan hydrolase activity
#115COMPOSITIONS AND METHODS FOR SUPPRESSION OF INHIBITOR FORMATION AGAINST COAGULATION FACTORS IN HEMOPHILIA PATIENTS
#116METHODS AND COMPOSITIONS FOR THE TREATMENT OF FABRY DISEASE
#117Cleavable lipids
#118Methods and compositions for the treatment of lysosomal storage diseases
#119Human alpha-galactosidase variants
#120and enrichment strategy targeting lymphocytes derived from vector transduced HSCs for therapy of disorders
#121Therapeutic regimen for the treatment of Fabry using stabilized alpha-galactosidase
#122Polynucleotides encoding α-galactosidase A for the treatment of Fabry disease
#123Disulfide bond stabilized polypeptide compositions and methods of use
#124Elution of biomolecules from multi-modal resins using MES and MOPS as mobile phase modifiers
#125PHARMACEUTICAL COMBINATION FOR TREATMENT OF FABRY DISEASE AND USE THEREOF
#126COMPOSITION OF DIGESTIVE ENZYMES AND APPETITE SUPPRESSANTS
#127LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY
#128Decellularization of plant cell culture materials for tissue engineering and drug delivery
#129GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
#130Compounds, devices, and uses thereof
#131Oligosaccharides comprising an aminooxy group and conjugates thereof
#132Recombinant α-galactosidase A for treatment of Fabry disease
#133Lipid nanoparticle compositions and methods for mRNA delivery
#134Cleavable lipids
#135Animal feed additives
#136Stabilized alpha-galactosidase and uses thereof
#137Treatment of α-galactosidase a deficiency
#138Treatment of Fabry disease
#139Targeted Therapeutic Proteins
#140Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
#141Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from and related organisms, methods
#142Compositions and methods for suppression of inhibitor formation against coagulation factors in hemophilia patients
#143Lipid nanoparticle compositions and methods for mRNA delivery
#144Lipid nanoparticle compositions and methods for mRNA delivery
#145Enzyme exhibiting fructan hydrolase activity
#146Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
#147Glycosylation independent proteins
#148ANTIBODY FORMULATIONS CONTAINING AMINO ACIDS
#149Scavenger receptor uptake for Fabry disease enzyme replacement therapy
#150Method for controlling enzyme productivity of microorganisms
#151Targeting of glycoprotein therapeutics
#152HEMICELLULASE ENRICHED COMPOSITIONS FOR ENHANCING HYDROLYSIS OF BIOMASS
#153Conjugate of therapeutic enzymes
#154Methods and compositions for the treatment of steatosis-associated disorders
#155Digital microbiology
#156Method for the simultaneous production of ethanol and a fermented, solid product
#157Polynucleotides encoding alpha-galactosidase A for the treatment of Fabry disease
#158Polynucleotides encoding α-galactosidase A for the treatment of Fabry disease
#159POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE
#160Methods of purifying recombinant alpha-Galactosidase A
#161STERILE CHROMATOGRAPHY AND MANUFACTURING PROCESSES
#162RECOMBINANT MICROALGAE INCLUDING KETO-ACYL ACP SYNTHASE
#163Cleavage of Fucose in N-Glycans
#164Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
#165MRNA for use in treatment of human genetic diseases
#166Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from and related organisms, methods
#167THERAPEUTIC COMPOSITIONS OF ALPHA-L-IDURONIDASE, IDURONATE-2-SULFATASE, AND ALPHA-GALACTOSIDASE A AND METHODS OF USE THEREOF
#168Cleavable lipids
#169Stabilized α-galactosidase and uses thereof
#170Methods and compositions for the treatment of Fabry disease
#171Enzyme formulation for reducing histamine intolerance
#172Targeted therapeutic proteins
#173Glycosylated lysosomal proteins, method of production and uses
#174Method for production of recombinant human alpha-galactosidase A from material containing contaminant host cell proteins by chromatography
#175Cleavable Lipids
#176α-galactosidase A and 1-deoxygalactonojirimycin co-formulation
#177HUMAN ALPHA-GALACTOSIDASE VARIANTS
#178Enzyme formulation for reducing histamine intolerance
#179Lipid nanoparticle compositions and methods for MRNA delivery
#180Method for the simultaneous production of ethanol and a fermented, solid product
#181Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose
#182Integrated continuous manufacturing of therapeutic protein drug substances
#183Treatment of alpha-galactosidase a deficiency
#184Alpha-galactosidase A and 1-deoxygalactonojirimycin co-formulation for the treatment of fabry disease
#185METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS
#186Use of Hydrolytic and Oxidative Enzymes to Dissolve Biofilm in Ears
#187ORALLY ADMINISTERED PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME, COMPRISING AN INTESTINAL MOTILITY MODIFIER, AN AGENT THAT PREVENTS GAS RETENTION, AND DIGESTIVE ENZYMES, AND PREPARATION METHOD THEREOF
#188NOVEL ALPHA-GALACTOSIDASE A DERIVATIVES
#189TARGETING OF GLYCOPROTEIN THERAPEUTICS
#190Compositions for Relieving the Symptoms of Gluten Sensitivity and Methods of Use Thereof
#191Method for preparing biological tissue
#192PHARMACEUTICAL OR NUTRITIONAL COMPOSITIONS CONTAINING GALACTOSIDASE, AND THEIR USE
#193Analytical method for determining the concentration of oxidized nanofibrillar cellulose in a sample
#194Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from and related organisms, methods
#195Compositions and methods for suppression of inhibitor formation against coagulation factors in hemophilia patients
#196Protein Formulations Containing Amino Acids
#197Recombinant glycoproteins and uses thereof
#198GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
#199Tailored oils produced from recombinant heterotrophic microorganisms
#200Treatment of α-galactosidase A deficiency
#201Polypeptides having a-L-Galactosidase Activity and Polynucleotides Encoding Same
#202Targeted therapeutic proteins
#203Enzyme formulation for use as food supplement
#204mRNA for use in treatment of human genetic diseases
#205Use of glycosidase in preparation of a milk product
#206Method of treating mucopolysaccharidosis type I or II
#207Stabilized alpha-galactosidase and uses thereof
#208Purification of recombinant alpha galactosidase A
#209Recombinant microalgae including keto-acyl ACP synthase
#210Yeast promoters for protein expression
#211Targeting of glycoprotein therapeutics
#212SUBCUTANEOUS ADMINISTRATION OF ALPHA-GALACTOSIDASE A
#213Thermophilic and thermoacidophilic biopolymer degrading genes and enzymes from and related organisms, methods
#214ELUTION OF BIOMOLECULES FROM MULTI-MODAL RESINS USING MES AND MOPS AS MOBILE PHASE MODIFIERS
#215MODIFIED FUNGAL CELL
#216STERILE CHROMATOGRAPHY AND MANUFACTURING PROCESSES
#217Sterile chromatography and manufacturing processes
#218Functionalized liposomes useful for the delivery of bioactive compounds
#219Integrated continuous manufacturing of therapeutic protein drug substances
#220α-galactosidase A and 1-deoxygalactonojirimycin co-formulation
#221Oligosaccharides comprising an aminooxy group and conjugates thereof
#222Method of treating GERD with alpha and beta galactosidases
#223mRNA for use in treatment of human genetic diseases
#224Glycosidase enzymes
#225Cleavable lipids
#226Plant cell culture expressing human lysosomal proteins and uses thereof
#227Integrated continuous manufacturing of therapeutic protein drug substances
#228Highly functional enzyme having alpha-galactosidase activity
#229Intranasal delivery of AAV encoding therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
#230Scavenger receptor uptake for fabry disease enzyme replacement therapy
#231Pharmaceutical composition for treating lysosomal storage disease
#232Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from and related organisms, methods
#233Use of glycosidase in preparation of a milk product
#234Highly functional enzyme having α-galactosidase activity
#235COMPOSITIONS AND METHODS FOR PRODUCING ANTIGEN-SPECIFIC INDUCED TOLEROGENIC DENDRITIC CELLS WITH SYNTHETIC NANOCARRIERS
#236INDUCED TOLEROGENIC DENDRITIC CELLS FOR INDUCING REGULATORY B CELLS
#237COMPOSITIONS AND METHODS RELATED TO INDUCED TOLEROGENIC DENDRITIC CELLS EXTERNALLY LOADED WITH MHC CLASS I-RESTRICTED EPITOPES
#238ALLERGEN-SPECIFIC INDUCED TOLEROGENIC DENDRITIC CELLS FOR ALLERGY THERAPY
#239ANTIGEN-SPECIFIC INDUCED TOLEROGENIC DENDRITIC CELLS TO REDUCE ANTIBODY RESPONSES
#240ANTIGEN-SPECIFIC INDUCED TOLEROGENIC DENDRITIC CELLS TO REDUCE CYTOTOXIC T LYMPHOCYTE RESPONSES
#241INDUCED TOLEROGENIC DENDRITIC CELLS TO REDUCE SYSTEMIC INFLAMMATORY CYTOKINES
#242INDUCED TOLEROGENIC DENDRITIC CELLS FOR GENERATING CD8+ REGULATORY T CELLS
#243DENDRITIC CELL SUBSETS FOR GENERATING INDUCED TOLEROGENIC DENDRITIC CELLS AND RELATED COMPOSITIONS AND METHODS
#244TRANSPLANTABLE GRAFT-SPECIFIC INDUCED TOLEROGENIC DENDRITIC CELLS AND METHODS OF USE
#245THERAPEUTIC PROTEIN-SPECIFIC INDUCED TOLEROGENIC DENDRITIC CELLS AND METHODS OF USE
#246Compositions Comprising Tailored Oils
#247Stabilized alpha-galactosidase and uses thereof
#248Tailored oils produced from recombinant heterotrophic microorganisms
#249Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
#250Human lysosomal proteins from plant cell culture
#251Glycosidase enzymes
#252comprising an α-galactosidase for removing immunodominant α-galactose monosaccharides from blood group B or AB reactive cells
#253mRNA for use in treatment of human genetic diseases
#254Targeting of glycoprotein therapeutics
#255Glycosidase Enzymes
#256Targeted therapeutic proteins
#257Glycan-specific analytical tools
#258Tailored oils produced from recombinant heterotrophic microorganisms
#259FOOD COMPOSITIONS COMPRISING TAILORED OILS
#260TREATMENT OF ALPHA-GALACTOSIDASE A DEFICIENCY
#261Human lysosomal proteins from plant cell culture
#262Human lysosomal proteins from plant cell culture
#263Highly functional enzyme having α-galactosidase activity
#264phytase
#265Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods
#266Hemicellulase Enriched Compositions for Enhancing Hydrolysis of Biomass
#267ENGINEERED MICROORGANISMS AND METHODS OF USE
#268α-galactosidases for removing immunodominant α-galactose monosaccharides from blood group B or AB reactive cells
#269Methods of preparing tissues for xenotransplantation using α-galactosidases
#270Treatment of α-galactosidase A deficiency
#271Glycosidase enzymes
#272SUBCUTANEOUS ADMINISTRATION OF ALPHA-GALACTOSIDASE A
#273Process for manufacturing tagatose using soy oligosaccharide
#274Stabilized aqueous alpha-galactosidase composition and methods relating thereto
#275USE OF HYDROLYTIC AND OXIDATIVE ENZYMES TO DISSOLVE BIOFILM IN EARS
#276PRODUCTION OF HIGH MANNOSE PROTEINS IN PLANT CULTURE
#277Highly functional enzyme having α-galactosidase activity
#278Bioactive raw vegetables
#279Methods of treating lysosomal storage related diseases by gene therapy
#280Oligosaccharides comprising an aminooxy group and conjugates thereof
#281Method of preparing non-human tissues for xenotransplantation using α-galactosidase
#282Production of high mannose proteins in plant culture and therapeutic uses thereof
#283TARGETED THERAPEUTIC PROTEINS
#284Glycosidase enzymes
#285Method for targeting lysosomal enzymes
#286Enzyme product for ruminants
#287ENZYMES HAVING GLYCOSIDASE ACTIVITY AND METHODS OF USE THEREOF
#288Hafnia phytase
#289Targeting of glycoprotein therapeutics
#290Human lysosomal proteins from plant cell culture
#291Bioactive raw vegetables
#292Enzyme Formulations
#293Genetic modification of the lung as a portal for gene delivery
#294Plant-derived alkaline alpha-galactosidase
#295Targeting of glycoprotein therapeutics
#296Process for producing a carbohydrate composition
#297Thermostable enzyme compositions
#298Treatment of α-galactosidase A deficiency
#299Plant-derived alkaline alpha-galactosidase
#300Methods of treating lysosomal storage related diseases by gene therapy