ClassID:

116865

C12Y304/21068 - CPC Classification

Classification description:

Hydrolases acting on peptide bonds, i.e. peptidases (3.4); Serine endopeptidases (3.4.21) Tissue plasminogen activator (3.4.21.68), i.e. tPA

Recent Application in this class:
#1
20260151389
2026-06-04

Use of Tetramethylpyrazine Nitrone Derivatives In The Treatment of Ischemic Stroke

#2
20260108481
2026-04-23

COMPOUNDS FOR PREVENTION AND TREATMENT OF HEMORRHAGE AND VASCULATURE INSTABILITY

#3
20260041778
2026-02-12

SHEAR RESPONSIVE APTAMER-BASED CONJUGATE FOR TARGETED DRUG DELIVERY

#4
20260007614
2026-01-08

THROMBOLYTIC AND NEURO/VASCULOPROTECTIVE NANOCONJUGATES

#5
20250276048
2025-09-04

Tissue Modifier And Uses Therefor

#6
20250255938
2025-08-14

CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO

#7
20250213695
2025-07-03

ULTRASOUND-MEDIATED GENE THERAPY FOR DEEP VEIN THROMBOSIS AND POST-THROMBOTIC SYNDROME

#8
20250205317
2025-06-26

METHODS AND COMPOSITIONS FOR THE TREATMENT OF STROKE

#9
20250186372
2025-06-12

FLEXIBLE INTERCONNECTED MICROPARTICLES ARRAYS: DEVICES, METHODS, COMPOSITIONS AND APPLICATIONS

#10
20250161330
2025-05-22

METHODS OF MEDICAL TREATMENT WITH SUR1-TRPM4 CHANNEL INHIBITORS

#11
20250115891
2025-04-10

TREATMENT FOR AIRWAY CAST OBSTRUCTION

#12
20250115640
2025-04-10

NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF

#13
20240424093
2024-12-26

DRUG REGIMEN FOR TREATMENT OF CEREBRAL ISCHEMIA

#14
20240382594
2024-11-21

MAGNETIC PARTICLE CONTROL AND VISUALIZATION

#15
20240360431
2024-10-31

ENGINEERED ALPHA-GALACTOSIDASE A (A-GAL A) PEPTIDES AND FUNCTIONAL VARIANTS THEREOF AND ASSOCIATED METHODS OF TREATING FABRY DISEASE

#16
20240358836
2024-10-31

DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS

#17
20240307331
2024-09-19

COMPOUNDS FOR PREVENTION AND TREATMENT OF HEMORRHAGE AND VASCULATURE INSTABILITY

#18
20240252452
2024-08-01

METHODS, COMPOSITIONS, AND DEVICES FOR DRUG / LIVE CELL MICROARRAYS

#19
20240226243
2024-07-11

CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO

#20
20240207372
2024-06-27

CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO

#21
20240207190
2024-06-27

FUCOIDAN-FUNCTIONALIZED POLYSACCHARIDE PARTICLES WITH T-PA FOR TARGETED THROMBOLYTIC THERAPY

#22
20240197840
2024-06-20

Tissue modifier and uses therefor

#23
20240173301
2024-05-30

2-IMINOBIOTIN FOR USE IN THE TREATMENT OF STROKE

#24
20240131118
2024-04-25

CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO

#25
20240115672
2024-04-11

TREATMENT OF AN IOP CONDITION

#26
20240084280
2024-03-14

FUSION PROTEIN CONTAINING TISSUE PLASMINOGEN ACTIVATOR OR ITS VARIANT AND TARGETING INTEGRIN ALPHA(IIB)BETA(3) AND THE APPLICATION THEREOF

#27
20240009187
2024-01-11

Methods of Treating Ischemic Disease by Administering an ATR Kinase Inhibitor

#28
20230404928
2023-12-21

NANOCAPSULE AND USES THEREOF

#29
20230263870
2023-08-24

SLOW RELEASE PLASMINOGEN ACTIVATOR FORMULATION FOR USE IN THE TREATMENT OF THROMBOTIC OR HAEMORRHAGIC DISEASE

#30
20230263832
2023-08-24

TARGETED DRUG DELIVERY TO SITES OF INTRAVASCULAR OCCLUSION

#31
20230146662
2023-05-11

PLASMINOGEN FOR USE IN TREATING AND PREVENTING LUNG DYSFUNCTION

#32
20230125052
2023-04-20

RED BLOOD CELL-DERIVED VESICLE

#33
20230103858
2023-04-06

MEDICAL USE OF ICARITIN

#34
20230085357
2023-03-16

INJECTABLE HIGH CONCENTRATION PHARMACEUTICAL FORMULATIONS AND METHODS OF MANUFACTURING AND USE THEREOF

#35
20220226445
2022-07-21

CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO

#36
20220211634
2022-07-07

THROMBOLYTIC AND NEURO/VASCULOPROTECTIVE NANOCONJUGATES

#37
20220184189
2022-06-16

METHODS FOR SAFE AND EFFECTIVE THROMBOLYSIS USING SEQUENTIAL ADMINISTRATION OF TISSUE PLASMINOGEN ACTIVATOR AND MUTANT PRO-UROKINASE

#38
20220162579
2022-05-26

Treatment for airway cast obstruction

#39
20220088039
2022-03-24

METHODS OF MEDICAL TREATMENT WITH SUR1-TRPM4 CHANNEL INHIBITORS

#40
20220056088
2022-02-24

PEPTIDE DIRECTED PROTEIN KNOCKDOWN

#41
20210363582
2021-11-25

BIOMARKERS FOR PREDICTING RISK OF ACUTE ISCHEMIC STROKE AND METHODS OF USE THEREOF

#42
20210361769
2021-11-25

Drug regimen for treatment of cerebral ischemia

#43
20210338818
2021-11-04

Magnetic particle control and visualization

#44
20210283254
2021-09-16

DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS

#45
20210275472
2021-09-09

Methods, compositions, and devices for making sustained biodegradable implants in tissue

#46
20210220450
2021-07-22

TREATMENT OF AN IOP CONDITION

#47
20210220446
2021-07-22

Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo

#48
20210214702
2021-07-15

PROCESS FOR PRODUCTION OF RECOMBINANT TNK-TPA BY PACKED-BED PERFUSION SYSTEM

#49
20210205420
2021-07-08

CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO

#50
20210170047
2021-06-10

Heteromultivalent particle compositions

#51
20210128497
2021-05-06

Compositions, methods and devices for forming implants from injected liquids

#52
20210008223
2021-01-14

SYNTHETIC PLATELETS

#53
20200268858
2020-08-27

Glaucoma treatment

#54
20200230237
2020-07-23

Drug regimen for treatment of cerebral ischemia

#55
20200230081
2020-07-23

Method of making an in situ sustained biodegradable drug delivery implant by filling an artificial tissue cavity

#56
20200157519
2020-05-21

Polypeptide for treating pathological blood clots

#57
20200147077
2020-05-14

Methods of treating ischemic disease by administering an ATR kinase inhibitor

#58
20200121622
2020-04-23

Methods for forming implants from injected thermoreversible gels

#59
20200046811
2020-02-13

METHODS AND COMPOSITIONS FOR MODULATING FGF23 LEVELS

#60
20200030417
2020-01-30

Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo

#61
20200024589
2020-01-23

Treatment for airway cast obstruction

#62
20190315849
2019-10-17

Method of reducing the effect of a stroke comprising administering an inhibitor of vascular endothelial growth factor B (VEGF-B)

#63
20190315819
2019-10-17

Peptide directed protein knockdown

#64
20190255174
2019-08-22

Magnetic particle control and visualization

#65
20190231862
2019-08-01

Gene vaccine for preventing and treating severe fever with thrombocytopenia syndrome

#66
20190192564
2019-06-27

Human blood-derived products having decreased fibrinolytic activity and uses thereof in hemostatic disorders

#67
20190175624
2019-06-13

Methods of medical treatment with SUR1-TRPM4 channel inhibitors

#68
20190151421
2019-05-23

METHOD FOR PREVENTING OR TREATING LIVER TISSUE DAMAGE AND ASSOCIATED DISEASES

#69
20190117744
2019-04-25

Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo

#70
20190117743
2019-04-25

Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo

#71
20190117742
2019-04-25

Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo

#72
20190105375
2019-04-11

Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo

#73
20190076510
2019-03-14

PROTEIN KINASE C INHIBITION TO EXTEND TISSUE PLASMINOGEN ACTIVATOR TREATMENT FOR ISCHEMIC DISEASE

#74
20190046479
2019-02-14

Methods, compositions, and devices for drug/live cell microarrays

#75
20190038748
2019-02-07

Devices for controlling magnetic nanoparticles to treat fluid obstructions

#76
20190022035
2019-01-24

Compositions, methods and devices for forming gel implants from injected liquids

#77
20180318443
2018-11-08

Heteromultivalent particle compositions

#78
20180311378
2018-11-01

SYNTHETIC PLATELETS

#79
20180311322
2018-11-01

Methods for safe and effective thrombolysis using sequential administration of tissue plasminogen activator and mutant pro-urokinase

#80
20180237513
2018-08-23

Method of treating stroke by administering a compound that inhibits VEGF-B signaling in combination with a thrombolytic agent

#81
20180223270
2018-08-09

Purification process for isolation and commercial production of recombinant TNK-tPA tenecteplase

#82
20180185475
2018-07-05

Drug regimen for treatment of cerebral ischemia

#83
20180140547
2018-05-24

COMPOSITIONS AND METHODS FOR ADMINISTRATION OF AN ENZYME TO A SUBJECT'S AIRWAY

#84
20180000756
2018-01-04

Compositions, methods and devices for forming implants from injected liquids

#85
20170285034
2017-10-05

Methods and materials for identifying and treating mammals having lung adenocarcinoma characterized by neuroendocrine differentiation

#86
20170202932
2017-07-20

METHODS FOR INHIBITING NEURON APOPTOSIS AND NECROSIS

#87
20170151307
2017-06-01

Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo

#88
20170128571
2017-05-11

Magnetic particle control and visualization

#89
20170095675
2017-04-06

Therapeutic magnetic control systems and contrast agents

#90
20170056521
2017-03-02

Fusion protein for treating rejection reaction in transplantation

#91
20170056520
2017-03-02

Multi-arm linker for treating rejection reaction in transplantation

#92
20170051268
2017-02-23

NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE

#93
20170007712
2017-01-12

GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS

#94
20160346327
2016-12-01

Synthetic Platelets

#95
20160346247
2016-12-01

Gelatinase inhibitors and prodrugs

#96
20160310580
2016-10-27

Pharmaceutical compositions of tenecteplase

#97
20160279249
2016-09-29

Aminofucoidan as a vector for fibrinolysis in thrombotic diseases

#98
20160243026
2016-08-25

Compositions, methods and devices for local drug delivery

#99
20160208274
2016-07-21

BLOOD CLOT-DISSOLVING PROTEINS PRODUCED IN SEEDS

#100
20160194623
2016-07-07

Mutated tissue plasminogen activators and uses thereof

#101
20160184414
2016-06-30

PKC activators and anticoagulant in regimen for treating stroke

#102
20160144001
2016-05-26

METHODS AND COMPOSITIONS FOR MODULATING FGF23 LEVELS

#103
20160089382
2016-03-31

Steroidal nitrones for the treatment and prevention of a cerebral stroke or ischaemia, alzheimer and parkinson disease and amyotrophic lateral sclerosis

#104
20160018399
2016-01-21

METHODS AND MATERIALS FOR IDENTIFYING AND TREATING MAMMALS HAVING LUNG ADENOCARCINOMA CHARACTERIZED BY NEUROENDOCRINE DIFFERENTIATION

#105
20160015833
2016-01-21

Heteromultivalent particle compositions

#106
20160000823
2016-01-07

METHODS AND COMPOSITIONS FOR IMPROVING HEMOSTASIS

#107
20150366953
2015-12-24

Glaucoma treatment

#108
20150343080
2015-12-03

GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS

#109
20150322421
2015-11-12

Treatment for airway cast obstruction

#110
20150266935
2015-09-24

Peptide directed protein knockdown

#111
20150258193
2015-09-17

Diagnostic marker for treatment of cerebral ischemia

#112
20150238502
2015-08-27

Compositions and Methods for Treating Stroke

#113
20150190482
2015-07-09

Plasminogen activator mutants as anti-fibrinolytic agents

#114
20150183844
2015-07-02

CHIMERIC NEUREGULINS AND METHOD OF MAKING AND USE THEREOF

#115
20150147276
2015-05-28

NANOTHERAPEUTICS FOR DRUG TARGETING

#116
20150093372
2015-04-02

Gelatinase inhibitors and prodrugs

#117
20140322190
2014-10-30

Pharmaceutical compositions and methods for digesting atherosclerotic plaques

#118
20140088009
2014-03-27

Chimeric neuregulins and method of making and use thereof

#119
20130052184
2013-02-28

Gelatinase inhibitors and prodrugs

#120
20130039902
2013-02-14

NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE

#121
20120310034
2012-12-06

Devices for controlling magnetic nanoparticles to treat fluid obstructions

#122
20120296149
2012-11-22

Methods of controlling magnetic nanoparticles to improve vascular flow

#123
20120232329
2012-09-13

Magnetic-based methods for treating vessel obstructions

#124
20120226093
2012-09-06

Magnetic-based systems for treating occluded vessels

#125
20120220517
2012-08-30

Glycopegylation methods and proteins/peptides produced by the methods

#126
20120034205
2012-02-09

PKC activators and anticoagulant in regimen for treating stroke

#127
20120027687
2012-02-02

FATTY ACID PROTEIN KINASE C ACTIVATORS AND ANTICOAGULANT FOR THE TREATMENT OF STROKE

#128
20120020948
2012-01-26

DAG-TYPE AND INDIRECT PROTEIN KINASE C ACTIVATORS AND ANTICOAGULANT FOR THE TREATMENT OF STROKE

#129
20110091436
2011-04-21

Use of matrix metalloproteinase-10 (MMP-10) for thrombolytic treatments

#130
20100330083
2010-12-30

PLASMINOGEN ACTIVATOR VARIANT FORMULATIONS

#131
20100048456
2010-02-25

Glycopegylation methods and proteins/peptides produced by the methods

#132
20090263373
2009-10-22

Non-neurotoxic plasminogen activating factors for treating of stroke

#133
20090004176
2009-01-01

Non-neurotoxic plasminogen activating factors for treating stroke

#134
20070026485
2007-02-01

Glycopegylation methods and proteins/peptides produced by the methods

#135
20070014779
2007-01-18

PLASMINOGEN ACTIVATOR VARIANT FORMULATIONS

#136
20060142195
2006-06-29

Non-neurotoxic plasminogen activating factors for treating of stroke

#137
20050048027
2005-03-03

Non-neurotoxic plasminogen activating factors for treating stroke

#138
15147958
2019-06-25

Compositions and methods for treating stroke