117112 ⎘
Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1) Asparaginase (3.5.1.1)
NON-FOULING OR SUPER STEALTH VESICLE
#2METHOD FOR TREATING CANCER BY USING COMBINATION OF ASPARAGINE INHIBITOR AND IMMUNE CHECKPOINT INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING COMBINATION OF ASPARAGINE INHIBITOR AND IMMUNE CHECKPOINT INHIBITOR
#3FUNCTIONALIZED BIOCATALYTICAL COMPOSITIONS
#4CELL THERAPY COMPOSITIONS AND METHODS OF USE THEREOF
#5COMBINATION THERAPIES INVOLVING L-ASPARAGINASE
#6USE OF A L-ASPARAGINASE IN COMBINATION WITH A FERROPTOSIS INDUCER FOR THE TREATMENT OF EXTRANODAL NATURAL KILLER/T-CELL LYMPHOMA
#7NOVEL TUMOR ANTIGEN-TARGETING ANTICANCER AGENT
#8GCN2 INHIBITOR (as amended)
#9FORMULATIONS OF POLYALKYLENE OXIDE-ASPARAGINASE AND METHODS OF MAKING AND USING THE SAME
#10ANALYTICAL METHOD AND THERAPEUTICAL AGENT FOR USE IN COMBINATION WITH L-ASPARAGINASE IN TUMOUR THERAPY
#11METHODS RELATED TO ADMINISTERING IMMUNOSUPPRESSANTS AND THERAPEUTIC MACROMOLECULES AT A REDUCED PHARMACODYNAMICALLY EFFECTIVE DOSE
#12DEGRADATION OF TOXINS IN VIVO
#13Variant Asparaginase Polypeptides for Medical Use
#14ERYTHROCYTE-BINDING THERAPEUTICS
#15RECOMBINANT L-ASPARAGINASE
#16COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS
#17METHODS FOR IMPROVING THE EFFICACY AND EXPANSION OF CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS
#18METHODS OF ADMINISTERING IMMUNOSUPPRESSANTS HAVING A SPECIFIED PHARMACODYNAMIC EFFECTIVE LIFE AND THERAPEUTIC MACROMOLECULES FOR THE INDUCTION OF IMMUNE TOLERANCE
#19FUNCTIONALIZED BIOCATALYTICAL COMPOSITIONS
#20FORMULATIONS OF POLYALKYLENE OXIDE-ASPARAGINASE AND METHODS OF MAKING AND USING THE SAME
#21MODIFIED L-ASPARAGINASE
#22STRAIN WITH IMPROVED AROMATIC AMINO ACID PRODUCTION CAPACITY BY ANSB GENE INACTIVATION
#23METHOD FOR TREATING CANCER
#24ASPARAGINASE PROTEINS
#25CELL THERAPY COMPOSITIONS AND METHODS OF USE THEREOF
#26METHODS OF TREATMENT WITH ASPARAGINASE
#27INJECTABLE HIGH CONCENTRATION PHARMACEUTICAL FORMULATIONS AND METHODS OF MANUFACTURING AND USE THEREOF
#28METHODS PROVIDING A THERAPEUTIC MACROMOLECULE AND SYNTHETIC NANOCARRIERS COMPRISING IMMUNOSUPPRESSANT LOCALLY AND CONCOMITANTLY TO REDUCE BOTH TYPE 1 AND TYPE IV HYPERSENSITIVITY
#29METHOD FOR TREATING CANCER
#30STRAIN WITH IMPROVED AROMATIC AMINO ACID PRODUCTION CAPACITY BY ANSB GENE INACTIVATION
#31Asparaginase Based Selection System for Heterologous Protein Expression in Mammalian Cells
#32DOSING AND ADMINISTRATION OF RECOMBINANT L-ASPARAGINASE
#33TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM
#34COMBINATION IMMUNOTHERAPY APPROACH FOR TREATMENT OF CANCER
#35METHODS OF PURIFYING CHARGE-SHIELDED FUSION PROTEINS
#36COMPOSITIONS AND METHODS FOR INDUCING ANTIGEN-SPECIFIC TOLERANCE
#37A LYOPHILIZED COMPOSITION OF PEGASPARGASE
#38Modified L-asparaginase
#39ASPARAGINASE-INDUCED GLUTAMINE DEPLETION COMBINED WITH BCL-2 INHIBITION FOR TREATMENT OF HEMATOLOGIC AND SOLID CANCERS
#40METHOD OF TREATING A MAMMAL, INCLUDING HUMAN, AGAINST CANCER USING METHIONINE AND ASPARAGINE DEPLETION
#41ASPARAGINASE THERAPEUTIC METHODS
#42Pegylated L-Asparaginase
#43In vivo protein N-acylation
#44Recombinant L-asparaginase
#45Erythrocyte-binding therapeutics
#46Variant Asparaginase Polypeptides for Medical Use
#47Method for production of recombinant asparaginase
#48PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
#49PEGylated L-asparaginase
#50Protein deamidase
#51Method for production of recombinant asparaginase
#52Truncated guinea pig L-asparaginase variants and methods of use
#53Site-specific polyethylene glycolylated (pegylated) asparaginase, preparation method therefor and use thereof
#54METHODS RELATED TO ADMINISTERING IMMUNOSUPPRESSANTS AND THERAPEUTIC MACROMOLECULES AT A REDUCED PHARMACODYNAMICALLY EFFECTIVE DOSE
#55Enzyme-responsive peptide nanofiber compositions and uses thereof
#56Antigen-specific tolerance and compositions for induction of same
#57Methods providing a therapeutic macromolecule and synthetic nanocarriers comprising immunosuppressant locally and concomitantly to reduce both type I and type IV hypersensitivity
#58METHODS COMPRISING DOSING COMBINATIONS FOR REDUCING UNDESIRED HUMORAL IMMUNE RESPONSES
#59METHODS OF ADMINISTERING IMMUNOSUPPRESSANTS HAVING A SPECIFIED PHARMACODYNAMIC EFFECTIVE LIFE AND THERAPEUTIC MACROMOLECULES FOR THE INDUCTION OF IMMUNE TOLERANCE
#60In vivo protein N-acylation
#61Bioresponsive particles
#62Compositions and methods for treating inflammatory related diseases or conditions using probiotics
#63Endotoxin free asparaginase
#64A HIGHLY STABLE, PROTEASE-RESISTANT E. COLI ASPARAGINASE
#65FORMULATIONS OF POLYALKYLENE OXIDE-ASPARAGINASE AND METHODS OF MAKING AND USING THE SAME
#66HUMAN ASPARAGINASE LACKING GLUTAMINASE ACTIVITY
#67Thermophilic L-asparaginase mutant and screening and fermentation methods thereof
#68COMPOSITIONS AND METHODS RELATED TO THERAPEUTIC CELL SYSTEMS FOR TUMOR GROWTH INHIBITION
#69Cell therapy compositions and methods of use thereof
#70COMPOSITIONS AND METHODS FOR INHIBITING SEED GERMINATION
#71BACTERIAL LEADER SEQUENCES FOR PERlPLASMIC PROTEIN EXPRESSION
#72Method for production of recombinant asparaginase
#73Method for production of recombinant
#74MICROBIAL PRODUCTION OF NICOTINIC ACID RIBOSIDE
#75L-asparaginase variants and fusion proteins with reduced L-glutaminase activity and enhanced stability
#76Method of treating a mammal, including human, against cancer using methionine and asparagine depletion
#77Pegylated L-Asparaginase
#78Enzyme-responsive peptide nanofiber compositions and uses thereof
#79Methods for determining the metabolic status of lymphomas
#80ASPARAGINASE
#81Antigen-specific tolerance and compositions for induction of same
#82Compositions for generation of immune tolerance to specific antigens
#83Compositions for inducing antigen-specific tolerance
#84Site-specific polyethylene glycolylated (pegylated) asparaginase, preparation method therefor and use thereof
#85Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
#86Erythrocyte-binding therapeutics
#87Thermostable asparaginase variants and polynucleotides encoding same
#88sp. bacteria and minicell derived therefrom, and use thereof
#89COMPOSITIONS AND METHODS FOR DECREASING BLOOD GLUCAGON LEVELS
#90Methods of evaluating patients using E-cadherin or vimentin
#91Combination immunotherapy approach for treatment of cancer
#92Therapeutic conjugates with sulfated dendrimers for intracellular targeting
#93Mutant with enhanced secretion of L-asparaginase and its application
#94Protein deamidase
#95Method for reducing the DNA content of a fermentation broth
#96Use of multi-arm polyethylene glycol modifier and application of multi-arm polyethylene glycol modifier in L-asparaginasum modification
#97Methods And Materials For Producing Enhanced Sugar, Starch, Oil, And Cellulose Output Traits In Crop Plants
#98Compositions and methods for treating inflammatory related diseases or conditions using probiotics
#99Methods for reducing immune responses
#100REDUCTION OF TRAF1 LEVELS COMBINED WITH NUTRIENT STRESS FOR TREATING LYMPHOCYTE-RELATED CANCERS
#101Compositions for inducing antigen-specific tolerance
#102Methods for induction of antigen-specific immune tolerance
#103Compositions for generating immune tolerance by targeting erythrocytes
#104RECOMBINANT L-ASPARAGINASE FROM ZYMOMONAS
#105Compounds, compositions and methods for the preparation of peptide/protein conjugates
#106Anticancer agent composition
#107Method for improving blood persistence of protein
#108THERAPEUTIC ASPARAGINASES
#109PROTEIN AQUEOUS SUSPENSION PREPARATION
#110Method for Producing a Food Product
#111Method for Producing a Food Product
#112Production of Polypeptides Without Secretion Signal in Bacillus
#113PEGylated L-asparaginase
#114NOVEL PROCESS FOR ENZYMATIC ACRYLAMIDE REDUCTION IN FOOD PRODUCTS
#115OLIGOMERIC INFLUENZA IMMUNOGENIC COMPOSITIONS
#116Method for Producing a Food Product
#117Asparaginase and treating diseases associated with asparagine dependence
#118Method for producing a polyglycerol nanogel for the encapsulation and release of biologically active substances
#119Methods of evaluating patients using E-cadherin and vimentin
#120Processes of producing a fermentation product
#121Thermostable asparaginase variants and polynucleotides encoding same
#122Heparosan-polypeptide and heparosan-polynucleotide drug conjugates and methods of making and using same
#123Medicament for the Treatment of Acute Myeloid Leukemia (AML)
#124Test for predicting neutralization of asparaginase activity
#125Erythrocyte-binding therapeutics
#126METHODS AND COMPOSITIONS FOR ENHANCING CD4+ REGULATORY T CELLS
#127Methods of administering immunosuppressants having a specified pharmacodynamic effective life and therapeutic macromolecules for the induction of immune tolerance
#128Methods comprising dosing combinations for reducing undesired humoral immune responses
#129Methods providing a therapeutic macromolecule and synthetic nanocarriers comprising immunosuppressant locally and concomitantly to reduce both type I and type IV hypersensitivity
#130Tolerogenic synthetic nanocarriers to reduce or prevent anaphylaxis in response to a non-allergenic antigen
#131Methods related to administering immunosuppressants and therapeutic macromolecules at a reduced pharmacodynamically effective dose
#132Asparaginase and treating diseases associated with asparagine dependence
#133Asparaginase enzyme variants and uses thereof
#134Processes of producing a fermentation product
#135Mutants of L-asparaginase
#136Variant activin receptor polypeptides and uses thereof
#137Method of preparing a heat-treated product
#138NOVEL ASPARAGINASES AND USES THEREOF
#139Variant activin receptor polypeptides and uses thereof
#140Process for Treating Vegetable Material with An Enzyme
#141Erythrocyte-binding therapeutics
#142COMPOSITIONS AND METHOD FOR DEIMMUNIZATION OF PROTEINS
#143Food production process
#144NOVEL PROCESS FOR ENZYMATIC ACRYLAMIDE REDUCTION IN FOOD PRODUCTS
#145Test for predicting neutralization of asparaginase activity
#146Method of preparing a heat-treated product
#147Pegylated L-Asparaginase
#148Asparaginases and uses thereof
#149ANTITUMOUR COMPOSITIONS CONTAINING TAXANE DERIVATIVES
#150NOVEL FOOD PRODUCTION PROCESS
#151Polysaccharide-protein conjugates reversibly coupled via imine bonds
#152NOVEL PROCESS FOR ENZYMATIC ACRYLAMIDE REDUCTION IN FOOD PRODUCTS
#153Heat-stable asparaginase for reducing acrylamide in food stuffs or stimulants
#154MEHODS AND COMPOSITIONS FOR INHIBITING IMPDH-1 ISOFORM 1
#155Asparaginases
#156Asparaginase enzyme variants and uses thereof
#157NOVEL ASPARAGINASES AND USES THEREOF
#158Asparaginases
#159COMPOSITIONS AND METHODS FOR SURFACE MODIFICATION OF ROOT VEGETABLE PRODUCTS
#160Method for reducing acrylamide in foods, foods having reduced levels of acrylamide and article of commerce
#161Asparaginases
#162Novel Process for Enzymatic Acrylamide Reduction in Food Products
#163Prcoess for Reducing Acrylamide
#164Method for increasing asparaginase activity in a solution
#165Process Flavours with Low Acrylamide
#166PROCESS FOR TREATING VEGETABLE MATERIAL WITH AN ENZYME
#167Methods for reducing asparagine in a food material using cooling
#168Method of Preparing a Heat-Treated Product
#169Asparaginases and method of preparing a heat-treated product
#170Gene products of which form odorous substances and improved biotechnological production methods based thereon
#171Novel food production process
#172Asparaginase and its use in food production
#173Asparaginases and method of preparing a heat-treated product
#174Method for reducing acrylamide formation in thermally processed foods
#175Antitumour compositions containing taxane derivatives
#176Method for reducing acrylamide in foods, foods having reduced levels of acrylamide and article of commerce
#177Method for reducing acrylamide formation in thermally processed foods
#178Asparaginase mutant with efficient expression, activity and stability