ClassID:

117205

C12Y305/01098 - CPC Classification

Classification description:

Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1) Histone deacetylase (3.5.1.98), i.e. sirtuin deacetylase

Recent Application in this class:
#1
20260146241
2026-05-28

Engineered CasPhi2 Nucleases

#2
20260070895
2026-03-12

CRYSTALLINE FORMS

#3
20250346903
2025-11-13

USE OF CONJUGATES OF MICRORNA AND CARDIAC TARGETING PEPTIDES FOR TREATING HEART FAILURE

#4
20250306008
2025-10-02

PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING MALIGNANT BREAST CANCER

#5
20250197899
2025-06-19

O-ACETYL HOMOSERINE-PRODUCING MICROORGANISM AND METHOD FOR PRODUCING O-ACETYL HOMOSERINE OR L-METHIONINE USING SAME

#6
20250179463
2025-06-05

HDAC4-MEDIATED NEUROPROTECTION

#7
20250051401
2025-02-13

IMPROVED PRODUCTION OF SECRETED PROTEINS IN YEAST CELLS

#8
20240424135
2024-12-26

Compositions For and Methods of Improving Viral Vectors

#9
20240254462
2024-08-01

COMPOSITIONS AND METHODS FOR MODULATING SECRETED FRIZZLED RECEPTOR PROTEIN 1 (SFRP1) GENE EXPRESSION

#10
20240254451
2024-08-01

HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)

#11
20240167034
2024-05-23

METHODS AND COMPOSITIONS FOR REJUVENATING CNS GLIAL POPULATIONS BY SUPPRESION OF TRANSCRIPTION FACTORS

#12
20240018265
2024-01-18

HDAC6 BINDING PROTEINS AND THEIR ANTI-VIRAL USE

#13
20230374549
2023-11-23

COMPOSITIONS AND METHODS FOR INHIBITING THE EXPRESSION OF MULTIPLE GENES

#14
20230212568
2023-07-06

MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS

#15
20230190961
2023-06-22

COMPOSITIONS AND METHODS FOR TREATING MYELIN DEFICIENCY BY REJUVENATING GLIAL PROGENITOR CELLS

#16
20230174978
2023-06-08

METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION

#17
20230054672
2023-02-23

METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION

#18
20220195398
2022-06-23

ABHD5 AND PARTIAL HDAC4 FRAGMENTS AND VARIANTS AS A THERAPEUTIC APPROACH FOR THE TREATMENT OF CARDIOVASCULAR DISEASES

#19
20220002778
2022-01-06

METHODS FOR THE DESIGN OF NONALLOSTERIC SIRTUIN ACTIVATING COMPOUNDS

#20
20210355465
2021-11-18

Engineered CRISPR-Cas9 Nucleases

#21
20210228741
2021-07-29

METHODS AND COMPOSITIONS TO STIMULATE RETINAL REGENERATION

#22
20200370089
2020-11-26

Methods for the design of mechanism-based sirtuin activating compounds

#23
20200283821
2020-09-10

Compounds and methods for detection of enzymes that remove methyl succinyl groups from epsilon-amino lysine moieties

#24
20200240995
2020-07-30

KDAC VARIANTS AND USES THEREOF

#25
20200149024
2020-05-14

Engineered CRISPR-Cas9 nucleases

#26
20200131517
2020-04-30

Treatment of Sirtuin (SIRT) related diseases by inhibition of natural antisense transcript to a Sirtuin (SIRT)

#27
20190338336
2019-11-07

Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from epsilon-amino lysine moieties

#28
20190314395
2019-10-17

USE OF COMPOUNDS ACTIVATING SIRT-3 FOR MIMICKING EXERCISE

#29
20190298747
2019-10-03

Methods for treatment of cancer by targeting SIRT5

#30
20190255106
2019-08-22

METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION

#31
20190161735
2019-05-30

Human fibrolamellar hepatocellular carcinomas (hFL-HCCs)

#32
20190024086
2019-01-24

Methods and compositions for modulating gene expression

#33
20180258464
2018-09-13

Methods for the design of mechanism-based sirtuin activating compounds

#34
20180258407
2018-09-13

ABHD5 and partial HDAC4 fragments and variants as a therapeutic approach for the treatment of cardiovascular diseases

#35
20180223328
2018-08-09

Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from epsilon-amino lysine moieties

#36
20180216088
2018-08-02

Engineered CRISPR-Cas9 nucleases

#37
20180179525
2018-06-28

Methods and compositions for modulating gene expression

#38
20180134662
2018-05-17

Aminopyridine Based Buffers with Wide Buffering Ranges Antibiotics and Myelin Disease Therapy

#39
20180110755
2018-04-26

Benzimidazole derivates useful as inhibitors of mammalian histone deacetylase activity

#40
20180080058
2018-03-22

Nanopatterned extracellular matrices enable cell-based assays with a mass spectrometric readout

#41
20180037903
2018-02-08

METHODS AND MEANS FOR INCREASING STRESS TOLERANCE AND BIOMASS IN PLANTS

#42
20170219594
2017-08-03

Screening method

#43
20170198333
2017-07-13

Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from epsilon-amino lysine moieties

#44
20170145421
2017-05-25

MIR-125A-5P AS A BIOMARKER FOR BREAST CANCER

#45
20170137824
2017-05-18

NEW TREATMENT AGAINST INFLUENZA VIRUS

#46
20160257937
2016-09-08

HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)

#47
20160235826
2016-08-18

HISTONE DEACETYLASE COMPOSITIONS AND USES THEREOF

#48
20160108376
2016-04-21

ABHD5 and partial HDAC4 fragments and variants as a therapeutic approach for the treatment of cardiovascular diseases

#49
20150376637
2015-12-31

METHODS AND MEANS FOR INCREASING STRESS TOLERANCE AND BIOMASS IN PLANTS

#50
20150296758
2015-10-22

HUMANIZED TRANSGENIC SINGLE NUCLEOTIDE POLYMORPHISM ANIMAL SYSTEMS

#51
20150209369
2015-07-30

Combination Therapy III

#52
20150184154
2015-07-02

NEW TREATMENT FOR NEURODEGENERATIVE DISEASES

#53
20150177248
2015-06-25

Use of SIRT7 as novel cancer therapy target and method for treating cancer using the same

#54
20150110768
2015-04-23

COMPOSITIONS AND METHODS COMPRISING SIRTUIN STIMULATORS AND NON-SIRTUIN PROTEIN DEACETYLASE INHIBITORS

#55
20140322136
2014-10-30

Methods for treating obesity

#56
20140213530
2014-07-31

Methods for treatment of cancer by targeting Sirt5

#57
20140017221
2014-01-16

Nucleic acid encoding superoxide dismutase variants and methods of use thereof

#58
20120252869
2012-10-04

TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT)

#59
20120183948
2012-07-19

Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties

#60
20120121568
2012-05-17

Superoxide dismutase variants and methods of use thereof

#61
20120071417
2012-03-22

Methods of inhibiting cancer cell growth with HDAC inhibitors and methods of screening for HDAC10 inhibitors

#62
20110319317
2011-12-29

TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRT1

#63
20110311508
2011-12-22

Method of modulating HSF-1

#64
20110237649
2011-09-29

TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRTUIN 1

#65
20110171196
2011-07-14

METHODS OF TREATMENT AND USES FOR CAMKII AND ITS INTERACTION WITH HDACS AND CALPAIN

#66
20110160287
2011-06-30

Potentiator of activity of anti-cancer agent and use thereof, and biomarker for prediction of prognosis in cancer patient and use thereof

#67
20110082189
2011-04-07

USE OF COMPOUNDS ACTIVATING SIRT-3 FOR MIMICKING EXERCISE

#68
20110077210
2011-03-31

HDAC REGULATION ASSAYS, COMPOUNDS AND THERAPEUTIC COMPOSITIONS

#69
20100303795
2010-12-02

MARKER OF PROSTATE CANCER

#70
20090311244
2009-12-17

Screening method

#71
20090162329
2009-06-25

COMPOSITIONS COMPRISING HDAC INHIBITORS AND METHODS OF THEIR USE IN RESTORING STEM CELL FUNCTION AND PREVENTING HEART FAILURE

#72
20080312175
2008-12-18

Methods and compositions for regulating HDAC4 activity

#73
20080038308
2008-02-14

Silencing RNA molecules and their use in bone formation

#74
20070142285
2007-06-21

Methods of treatment and uses for CaMKII and its interaction with HDACs and calpain