170636 ⎘
Assays involving biological materials from specific organisms or of a specific nature; Enzymes; Proenzymes; Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7); Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
Sub-classes:TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS
#2BIOMARKER COMPOSITIONS AND METHODS OF USE THEREOF
#3ANTI-MERTK ANTIBODIES AND METHODS OF USE THEREOF
#4MARKER FOR DNA DAMAGE IN PROXIMITY OF TRANSCRIBED GENOMIC LOCI AND METHODS FOR IDENTIFYING AND/OR QUANTIFYING THESE DNA DAMAGES
#5SFLT1 MARKER PANELS FOR EARLY DETECTION OF SEPSIS
#6GDF15 MARKER PANELS FOR EARLY DETECTION OF SEPSIS
#7COMBINATION THERAPY WITH A MEK INHIBITOR AND A SRC INHIBITOR FOR THE TREATMENT OF COLORECTAL CANCER
#8INHIBITION OF FGR REDUCES FIBROSIS
#9METHODS FOR PREDICTING THE RESPONSE OF A PATIENT TO TREATMENT WITH A PD-1 OR PD-L1 IMMUNE CHECKPOINT INHIBITOR
#10RET (REARRANGED DURING TRANSFECTION) FOR THE ASSESSMENT OF STROKE
#11PROGNOSTIC BIOMARKER OF CANCER
#12Method for Diagnosing Cancer, Cancer Diagnosis Composition, Cancer Diagnosis Kit, Method for Evaluating State of Cancer, and Method for Screening Agents for Preventing and/or Treating Cancer
#13Bruton's Tyrosine Kinase as Anti-Cancer Drug Target
#14Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer
#15METHODS AND APPARATUS FOR CONDUCTING MULTIPLE MEASUREMENTS ON A SAMPLE
#16Treatment of cancers using PI3 kinase isoform modulators
#17METHOD FOR DETECTING ATP BY USING PERSONAL BLOOD GLUCOSE METER
#18High temperature selection of nucleotide-supported carbohydrate vaccines and resulting glycosylated oligonucleotides
#19METHODS AND APPARATUS FOR CONDUCTING MULTIPLE MEASUREMENTS ON A SAMPLE
#20METHOD FOR PREDICTING THE RESPONSE TO HER2-DIRECTED THERAPY
#21Methods of diagnosing and prognosing lung cancer
#22Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer
#23Compositions for detecting mutant anaplastic lymphoma kinase in human lung cancer
#24CDK12 inhibitors and their uses
#25Method for measuring tyrosine phosphatase and tyrosine kinase activity
#26METHODS USING AXL AS A BIOMARKER OF EPITHELIAL-TO-MESENCHYMAL TRANSITION
#27METHODS OF TREATING LUNG CANCER BY ADMINISTRATION OF AN ALK INHIBITOR
#28Methods And Compositions For Detection Of Cowden Syndrome (CS) And CS-Like Syndrome
#29METHOD FOR PREDICTING THE RESPONSE TO HER2-DIRECTED THERAPY
#30TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS
#31Methods of diagnosing and treating autism spectrum disorders
#32Bruton's tyrosine kinase as anti-cancer drug target
#33Systems and methods for electrochemical triglycerides assays
#34Bruton's tyrosine kinase as anti-cancer drug target
#35Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
#36USE OF PROTEIN S100A12 AS A MARKER FOR COLORECTAL CANCER
#37Method for detection of a TECR:PKN1 or an ANXA4:PKN1 gene fusion
#38Covalently linked thermostable kinase for decontamination process validation
#39Biomarkers associated with schizophrenia
#40Anticancer adjuvant composition containing RIP3 expression promoter as active ingredient, method for screening for anticancer adjuvant enhancing sensitivity of anticancer drug by promoting RIP3 expression, and method for monitoring sensitivity of anticancer drug
#41Biaryl bruton's tyrosine kinase inhibitors
#42High temperature selection of nucleotide-supported carbohydrate vaccines and resulting glycosylated oligonucleotides
#43METHODS AND APPARATUS FOR CONDUCTING MULTIPLE MEASUREMENTS ON A SAMPLE
#44Compositions and methods for treating cancer with JAK2 activity
#45Methods and compositions for detection of Cowden syndrome (CS) and CS-like syndrome
#46Methods and means for treatment of osteoarthritis
#47Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer
#48Fluorescent probe sensing tyrosine kinase and use thereof
#49Bruton's tyrosine kinase as anti-cancer drug target
#50SYSTEMS AND METHODS FOR FACILITATING DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER BASED ON DETECTION OF HER3 ACTIVATION
#51HER3 protein SRM/MRM assay
#52Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for tor kinase inhibitory activity
#53Biomarker for the prediction of responsiveness to an anti-tumour necrosis factor alpha (TNF) treatment
#54FURTHER USE OF PROTEIN KINASE N BETA
#55TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS
#56Substituted pyrazolo[1,5-a]pyrimidines as Syk inhibitors
#57USE OF PROTEIN S100A12 AS A MARKER FOR COLORECTAL CANCER
#58PEPTIDE AND ANTIBODY LIBRARIES AND USES THEREOF
#59Method for predicting the response to HER2-directed therapy
#60Mutant ROS expression in human cancer
#61Methods for Screening Inhibitors of Tau Phosphorylation By Casein Kinase I
#62Biomarker for the prediction of responsiveness to an anti-tumour necrosis factor alpha (TNF) treatment
#63Profiling of signal pathway proteins to determine therapeutic efficacy
#64Induced pluripotent stem cell model of chronic myeloid leukemia revealed olfactomedin 4 as a novel therapeutic target in leukemia stem cells
#65Biosensor for detecting RAF/KSR family kinase dimerization and uses thereof
#66Genes and polypeptides relating to breast cancers
#67Molecules inhibiting a metabolic pathway involving the Syk protein tyrosine kinase and method for identifying said molecules
#68Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity
#69Bruton's tyrosine kinase as anti-cancer drug target
#70MAPKAP kinase-2 as a specific target for blocking proliferation of P53-defective
#71Imidazopyrazine Syk inhibitors
#72Therapeutic and diagnostic applications targeting TNK-1
#73Her3 protein SRM/MRM assay
#74Total and phosphorylated IL-1 receptor-associated kinase-1 and IL-1 receptor-associated kinase-4 as a biomarker for cancer progression and chemotherapy resistance
#75Upregulation of rack-1 in melanoma and its use as a marker
#76Compositions and methods for treating cancer and neurodegenerative diseases
#77Identification, assessment, and therapy of cancers with innate or acquired resistance to ALK inhibitors
#78Method for Diagnosing or Determining the Prognosis of Colorectal Cancer (CRC) Using Novel Autoantigens: Gene Expression Guided Autoantigen Discovery
#79PTP1B inhibitors
#80COMPOSITIONS AND METHODS FOR DETECTING NOONAN SYNDROME
#81Method for Diagnosing or Determining the Prognosis of Colorectal Cancer (CRC) Using Novel Autoantigens: Gene Expression Guided Autoantigen Discovery
#82Methods And Compositions For Detection Of Cowden Syndrome (CS) and CS-Like Syndrome
#83Gene defects and mutant ALK kinase in human solid tumors
#84Method for screening anti-cancer compounds inhibiting function of TM4SF5 and anti-cancer composition containing chalcone compounds
#85Methods and uses of KSR kinase, and mutations thereof
#86RAF DIMERS AND USES THEREOF
#87MATERIALS AND METHODS FOR THE IDENTIFICATION OF DRUG-RESISTANT CANCERS AND TREATMENT OF SAME
#88SERUM BIOMARKERS FOR CHAGAS DISEASE
#89Methods of treating lung cancer using inhibitors anaplastic lymphoma kinase
#90Further use of protein kinase N beta
#91Bruton's tyrosine kinase as anti-cancer drug target
#92PTP1B INHIBITORS
#93METHODS USING AXL AS A BIOMARKER OF EPITHELIAL-TO-MESENCHYMAL TRANSITION
#94METHODS FOR MODULATING TOLL-LIKE RECEPTOR MEDIATED ACTIVATION OF CELLS OF THE INNATE SYSTEM BY MODULATING XBP-1 ACTIVITY
#95Methods and Compounds for the Diagnosis of Inflammatory Disease and Identification of Pharmacological Agents Useful in the Treatment of Inflammatory Disease
#96METHODS FOR MODULATING METABOLIC AND CIRCADIAN RHYTHMS
#97Prohibitin as target for cancer therapy
#98Antibody specific for a mammalian sphingosine kinase type 2 isoform protein and methods of use thereof
#99Kinase and phosphatase assays
#100AKT tyrosine 176 phosphorylation cancer biomarker
#101Anti-MST1R antibodies and uses thereof
#102PROTEIN KINASE C GAMMA AS A BIOMARKER FOR NEUROPSYCHOLOGICAL AND COGNITIVE FUNCTIONS IN THE CENTRAL NERVOUS SYSTEM
#103Methods and means for treatment of osteoarthritis
#104Method of protecting against heart failure
#105Mutant ROS expression in human cancer
#106METHODS OF IDENTIFYING MODULATORS OF THE PP2A B56 BETA REGULATORY SUBUNIT
#107Method for screening cancer therapeutic agent using galectin-3, GSK-3β, and fascin-1
#108METHOD FOR JUDGING SUSCEPTIBILITY OF CANCER CELLS TO ANTHRACYCLINE ANTICANCER AGENT AND COMPUTER PROGRAM
#109Gene defects and mutant ALK kinase in human solid tumors
#110Methods and Compositions for the Diagnosis and Treatment of Cyclin A-1 Associated Conditions
#111Fluorescently Or Spin-Labeled Kinases For Rapid Screening And Identification Of Novel Kinase Inhibitor Scaffolds
#112ABNORMAL ALTERATIONS OF PKC ISOZYMES PROCESSING IN ALZHEIMER'S DISEASE PERIPHERAL CELLS
#113METHODS RELATED TO CASEIN KINASE II (CK2) INHIBITORS AND THE USE OF PURINOSOME-DISRUPTING CK2 INHIBITORS FOR ANTI-CANCER THERAPY AGENTS
#114Method for treating cancer by administering antibody to ephrin type-A receptor 7
#115STAT3 and TYK2 as drug targets for neurodegenerative diseases
#116Covalently linked thermostable kinase for decontamination process validation
#117EMISSION RATIOMETRIC INDICATORS OF PHOSPHOINOSITIDES
#118METHOD OF MODULATION OF PROTEIN PHOSPHORYLATION-DEPENDENT CONFORMATIONAL TRANSITIONS WITH LOW MOLECULAR WEIGHT COMPOUNDS
#119Methods and products relating to GSK3β regulation
#120Imaging Mass Spectrometry for Improved Prostrate Cancer Diagnostics
#121Method for predicting the response to HER2-directed therapy
#122Genes and polypeptides relating to breast cancers
#123EYA2S As Modifiers of the PTEN/AKT Pathway and Methods of Use
#124METHODS OF DIAGNOSING AND PROGNOSING LUNG CANCER
#125COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF CANCER
#126MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES
#127Methods and apparatus for conducting multiple measurements on a sample
#128Method for Treating Hepatitis C Infection
#129Biomarker for the prediction of responsiveness to an anti-tumour necrosis factor alpha (TNF) treatment
#130NOVEL FER -LIKE PROTEIN, PHARMACEUTICAL COMPOSITIONS CONTAINING IT AND METHOD FOR ITS USE
#131Gene defects and mutant ALK kinase in human solid tumors
#132Diagnostic and Therapeutic Utility of Tribbles-2 in Human Cancers
#133Further Use of Protein Kinase N Beta
#134ZAP-70 as predictor and modulator of effector function of T cells
#135MOLECULAR MODIFICATION ASSAYS
#136Gene defects and mutant ALK kinase in human solid tumors
#137EXPRESSION PROFILE OF PROSTATE CANCER
#138Upregulation of RACK-1 in melanoma and its use as a marker
#139Antibodies to Phosphorylated IRAK4
#140BRUTON'S TYROSINE KINASE AS ANTI-CANCER DRUG TARGET
#141METHODS AND COMPOSITIONS RELATED TO DLK-1 AND THE P38 MAPK PATHWAY IN NERVE REGENERATION
#142Kinase and phosphatase assays
#143Gene defects and mutant ALK kinase in human solid tumors
#144MULTIPLE MECHANISMS FOR MODULATION OF THE PI3 KINASE PATHWAY
#145Compositions and Methods for Treating Amyotrophic Lateral Sclerosis
#146Profiling for Determination of Response to Treatment for Inflammatory Disease
#147Intracellular reporters
#148DETERMINATION OF RESPONDERS TO CHEMOTHERAPY
#149Method of regulating mammalian target-of-rapamycin activity by interaction between phospholipase D and raptor
#150GALK1S AS MODIFIERS OF THE PTEN/AKT PATHWAY AND METHODS OF USE
#151Assay particles and methods of use
#152Methods of modulating metabolic memory
#153Biomarkers for chronic vascular dysfunction
#154Imidazopyrazine Syk inhibitors
#155METHOD OF DETECTING LIVER CANCER, DIAGNOSTIC FOR LIVER CANCER AND REMEDY FOR CANCER
#156Cell-signaling assays
#157UL97 INHIBITORS FOR TREATMENT OF PROLIFERATIVE DISORDERS
#158In vitro method for diagnosing prostate cancer
#159Methods and Compounds for the Diagnosis of Inflammatory Disease and Identification of Pharmacological Agents Useful in the Treatment of Inflammatory Disease
#160CDC6S AS MODIFIERS OF THE PTEN/AKT PATHWAY AND METHODS OF USE
#161PHOSPHO-SPECIFIC ANTIBODIES TO FLT3 (TYR969) AND USES THEREOF
#162Methods and compositions for detection of Cowden Syndrome (CS) and CS-like syndrome
#163Method for screening anti-cancer compounds inhibiting function of TM4SF5 and anti-cancer composition containing chalcone compounds
#164PARALLEL PROFILLING OF SIGNALING PATHWAYS
#165IKB kinase, subunits thereof, and methods of using same
#166SCREENING METHOD FOR THERAPEUTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS
#167PROCESS FOR DETECTING ENZYME ACTIVITY IN AN IMMUNOASSAY
#168Compositions and methods for detecting Noonan syndrome
#169Method of regulating mammalian target-of-rapamycin activity by interaction between phospholipase D and Rheb
#170USE OF PROTEIN S100A12 AS A MARKER FOR COLORECTAL CANCER
#171Parkinson's Disease-Related Gene GRK5 and Uses Thereof
#172Hip kinase for fertility control
#173Crystallization of C-Jun N-Terminal Kinase 3 (JNK3)
#174Methods and compositions for treating cellular proliferative diseases
#175DETECTION OF PKC-IOTA AS A BIOMARKER FOR BRAIN TUMORIGENESIS
#176Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
#177Cellular assay method for identifying pkc-0 inhibitors
#178Mammalian sphingosine kinase type 2 isoforms, cloning, expression and methods of use thereof
#179DNA encoding polypeptide capable of modulating muscle-specific tyrosine kinase activity
#180Gene defects and mutant ALK kinase in human solid tumors
#181RORS as modifiers of the p21 pathway and methods of use
#182Autoantibody detection for cancer diagnostics
#183Inhibition of polo kinase by matrimony maintains G2 arrest in the meiotic cell cycle
#184Assays for determining compounds which modulate TRAM phosphorylation
#185Cancer diagnostic device
#186Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
#187AMPK Deficient Animals, Screening Methods, And Related Therapeutics And Diagnostics
#188METHOD FOR EXTRACTING QUANTITATIVE INFORMATION RELATING TO AN INFLUENCE ON A CELLULAR RESPONSE
#189Soluble ErbB3 method of detection
#190Mapkap kinase-2 as a specific target for blocking proliferation of P53-defective cells
#191Oncoprotein protein kinase antibody kit
#192Methods
#193COMPOSITIONS AND METHODS FOR MODULATION OF PLK1 KINASE ACTIVITY
#194Soluble ErbB3 receptor isoforms
#195Use of Serum/Glucocorticoid-Regulated Kinase
#196Methods and Compositions for Diagnosis and Treatment of Disorders Involving Macrophages
#197Soluble ErbB3 and treatment of cancer
#198Methods for inhibiting heregulin and treating cancer
#199Soluble ErbB3 receptor isoforms
#200Treating cancer
#201Prohibitin as Target for Cancer Therapy
#202Bruton's tyrosine kinase activity probe and method of using
#203Protein kinase C gamma as a biomarker for neuropsychological and cognitive functions in the central nervous system
#204Methods and Compositions for the Treatment of Lipid-Associated Disorders
#205OPTICAL PROBES AND ASSAYS
#206Method for Identifying Inhibitors Using a Homology Model of Polo-Like Kinase 1
#207Method for determining the efficacy of an anthracycline anticancer agent
#208Method of Detecting Liver Cancer, Diagnostic for Liver Cancer and Remedy for Cancer
#209Method of screening for inhibitors of tau protein phosphororylation by tyrosine kinase c-Abl
#210Nucleic acid molecules encoding emission ratiometric indicators of phosphoinositides
#211Method for assessing proliferation inhibiting effect of inhibitor, and method for determining sensitivity of tumor cell to inhibitor
#212Compositions and methods for detecting and treating renal injury and inflammation
#213Method of treating cell-migration conditions or diseases
#214Novel Cdk11 molecules and uses thereof
#215Diagnostics and Therapeutics for Diseases Associated With Glycogen Synthase Kinase 3 Beta (Gsk3b)
#216Integrin-linked kinase and its uses
#217Use of a Novel Polymorphism in the Hsgk1 Gene in the Diagnosis of Hypertonia an Use of the Sgk Gene Family in the Diagnosis and Therapy of the Long Qt Syndrome
#218Immunohistochemical Methods
#219METHOD FOR DETERMINING ACTIVITY OF CELL CYCLE REGULATORY FACTOR AND METHOD FOR DIAGNOSING CANCER USING THE SAME
#220Methods for Identifying Modulators of Active Kit Tyrosine Kinase Receptor
#221Integrin-linked kinase and its uses
#222Method for judging feature of malignant tumor
#223P38 MAPK pathway predicts endocrine-resistant growth of human breast cancer and provides a novel diagnostic and treatment target
#224Assay system for specific inhibitors of protein kinase C-related kinases
#225Detection of PKC-iota as a biomarker for brain tumorigenesis
#226Assay methods and systems
#227Protein tyrosine kinase substrate lat and its use in the identification of (ANT)agonists of the kinase
#228Map2k6 as modifier of branching morphogenesis and methods of use
#229Oncoprotein protein kinase
#230Kinase and phosphatase assays
#231Determination of responders to chemotherapy
#232Rsk inhibitors and therapeutic uses thereof
#233Assay particles and methods of use
#234Peptide that inhibits janus kinase
#235Crystal structure of the ITK kinase domain
#236Crystal structure of human Pim-1 kinase protein complexes and binding pockets thereof, and uses thereof in drug design
#237Predictive Methods For Cancer Chemotherapy
#238Assay for protein tyrosine phosphatases
#239Methods of preventing or treating cell migration mediated conditions or diseases
#240Methods and compositions for modulating CHK2 pathways and methods for screening for same
#241Methods and materials for characterizing and modulating interaction between heregulin and HER3
#242Compositions, kits and assays containing reagents directed to cortactin and an ARG/ABL protein kinase
#243Methods and compounds for the diagnosis of inflammatory disease and identification of pharmacological agents useful in the treatment of inflammatory disease
#244Molecular modification assays
#245Oncoprotein protein kinase
#246Methods and compositions for treating cellular proliferative diseases
#247Rors as modifiers of the p21 pathway and methods of use
#248System and method for providing personalized healthcare for alzheimer's disease
#249Predictive markers in cancer therapy
#250Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
#251Methods and compositions for the diagnosis and treatment of cyclin A-1 associated conditions
#252Protein tyrosine kinase substrate LAT and its use in the identification of (ANT) agonists of the kinase
#253Method for the idenification of ligands
#254IKK-alpha proteins, nucleic acids and methods
#255Compositions and methods for diagnosing, preventing, and treating cancers
#256Regulation of human serine-threonine protein kinase
#257Tumor suppressor gene
#258Serum biomarkers for Chagas disease
#259Methods and reagents for treating autoimmune disorders
#260Methods and compositions for the identification, assessment, and therapy of small cell lung cancer
#261Rsk inhibitors and therapeutic uses thereof
#262Cancer associated protein kinases and their uses
#263Regulation of human serine/threonine kinase
#264DNA dependent protein kinase catalytic subunit phosphorylation sites and antibodies thereto
#265PYK2 crystal structure and uses
#266Oncoprotein protein kinase
#267Methods for diagnosing and treating autoimmune disease
#268Cell-signaling assays
#269Tyrosine kinase inhibitors
#270Kinase and phosphatase assays
#271Detection of protein conformations in single cells
#272Oncoprotein protein kinase
#273Prognostic evaluation of cancer
#274Compositions and methods for the suppression of mammary epithelial cell proliferation
#275Diagnosis and treatment of AUR1 and/or AUR2 related disorders