170784 ⎘
Screening for compounds of potential therapeutic value Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
ANTIFUGETACTIC AGENTS FOR THE TREATMENT OF CANCERS
#302Methods for selecting protease resistant polypeptides
#303Anti-ANG2 antibody
#304CKAP4-molecular-targeted antitumor agent
#305Interaction of methylated LSD1 and CHD1, a compound inhibiting this interaction for use in therapy, and a screening method for such a compound
#306Methods for screening compounds for treating or preventing a viral infection or a virus-related condition
#307Biological Materials and Uses Thereof
#308HISTONE PROTEIN UBIQUITINATION AS A CANCER BIOMARKER
#309POLYPEPTIDE FRAGMENTS COMPRISING ENDONUCLEASE ACTIVITY AND THEIR USE
#310Agent for controlling cells constituting cancer microenvironment or inflammatory microenvironment
#311MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS
#312METHOD FOR DETECTING MOLECULES THAT INHIBIT THE INTERACTION OF CD36 PROTEIN WITH AMYLOID BETA
#313USE OF BLOCKING-REAGENTS FOR REDUCING UNSPECIFIC T CELL-ACTIVATION
#314Pharmaceuticals and methods for treating hypoxia and screening methods therefor
#315FLT3 receptor antagonists for the treatment or the prevention of pain disorders
#316Methods for modulating ATRX-dependent gene repression
#317Bak binding proteins
#318Method for identifying a compound useful with myosin regulatory light chain polypeptide antibody for treatment of an inflammatory disease
#319Substrates for FLT3 kinase and uses thereof
#320NEUROTOXIC TARGET FOR AMYLOSPHEROID, METHOD AND MATERIAL FOR REDUCING THE NEUROTOXICITY OF AMYLOSPHEROID, AND USE THEREOF
#321ANTIFUGETACTIC AGENTS FOR THE TREATMENT OF CANCERS
#322METHOD FOR SCREENING COMPOUND SPECIFICALLY SUPPRESSING FORMATION OF CAVEOLAE OF CANCER CELLS, SCREENING KIT, VECTOR AND TRANSFORMANT TO BE USED IN KIT, AND METHOD FOR SELECTING PATIENT FOR WHOM MOLECULARLY TARGETED DRUG IS INDICATED
#323Uses of FAHD1
#324Inhibitors of mitochondrial fission and methods of use thereof
#325BIOMARKER FOR DETERMINING MITOCHONDRIAL DAMAGE IN FRIEDREICH'S ATAXIA
#326Compositions and methods for treating malignancies
#327COMPOSITIONS AND METHODS FOR MODULATING BODY WEIGHT
#328Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
#329Methods of identifying modulators of sestrin-gator-2 interaction for modulating mTORC1 activity
#330COMPLIMENT FACTOR I BIOASSAY
#331ANTI-HIMF ANTIBODIES TO TREAT LUNG DISEASES
#332IDENTIFICATION OF MODULATORS OF BINDING PROPERTIES OF ANTIBODIES REACTIVE WITH A MEMBER OF THE INSULIN RECEPTOR FAMILY
#333Cancer treatment and immune system regulation through FAT10 pathway inhibition
#334Lysosome membrane protein 2 (LIMP-2) based peptides and related uses
#335Binding domains directed against GPCR:G protein complexes and uses derived thereof
#336Method and Compositions for Inducing Differentiation of Myeloid Derived Suppressor Cell to Treat Cancer and Infectious Diseases
#337Desmoglein 2 (DSG2) binding proteins and uses therefor
#338MULTIPROTEIN ASSEMBLIES
#339CSN5 polypeptides and uses thereof for screening therapeutic agents
#340METHODS FOR IDENTIFYING COMPOUNDS THAT ALTER THE ACTIVITY OF IRHOM POLYPEPTIDES AND USE THEREOF
#341AGENTS USEFUL IN DIAGNOSTIC AND THERAPY OF BETA-AMYLOID AGGREGATION RELATED DISORDERS AND SCREENING METHODS
#342Biosensor based on Gβγ-interacting proteins to monitor G-protein activation
#343Prophylactic agent and therapeutic agent for fibrodysplasia ossificans progressiva
#344Compositions and methods for regulating glucose metabolism
#345Feline bitter taste receptors and methods
#346Compositions and methods for detecting S-nitrosylation and S-sulfinylation
#347METHOD FOR MONITORING CATHEPSIN S INHIBITION
#348Tyrosine kinase biosensors and methods of use
#349Methods, compositions, diagnostics and assays for the treatment of Alzheimer's disease
#350Method of Modulating Protein 14-3-3 Functionality By Facilitating or Inhibiting Phosphorylation
#351COMPOSITIONS AND METHODS FOR IDENTIFYING ENZYME MODULATORS OR INHIBITORS
#352Use of DDX3X inhibitors for the treatment of pneumovirus infections
#353Methods for breast cancer treatment
#354COMPOSITIONS AND METHOD FOR IDENTIFYING ENZYME AND TRANSPORT PROTEIN INHIBITORS
#355TFPI inhibitors and methods of use
#356RECEPTORS OF RSPO2 AND RSPO3
#357Dendritic cell immune receptor activator, method for activating dendritic cell immune receptor, osteoclast formation inhibitor, method for inhibiting osteoclast formation, dendritic cell differentiation/proliferation inhibitor, method for inhibiting dendritic cell differentiation/proliferation, cytokine production inhibitor, method for inhibiting cytokine production, therapeutic method and screening method
#358Engineered renal tissues, arrays thereof, and methods of making the same
#359Methods of measuring factor D activity and potency of factor D inhibitors
#360Methodologies for measuring isopeptidase activity in biological samples in a high throughput manner
#361Methods and reagents for analyzing protein-protein interfaces
#362FGF21 protein with enhanced binding affinity for β-Klotho for the treatment of type II diabetes, obesity, and related metabolic disorders
#363CELL LINE-BASED REDIRECTED T-CELL CYTOTOXICITY ASSAY
#364Sensor peptide and methods of use thereof to identify substances that modulate gibberellic acid action
#365Methods and Pharmaceutical Compositions for the Treatment of Diseases Mediated by the NRP-1/OBR Complex Signaling Pathway
#366Target for Firmicutes and Related Bacteria: The PRP Protease
#367Polypeptides and uses thereof for reducing CD95-mediated cell motility
#368Compositions and methods for treating hepatitis B
#369Chimeric fibroblast growth factor 21 proteins and methods of use
#370Methods and pharmaceutical compositions for the treatment of beta-thalassemias
#371DDX5 AND ASSOCIATED NON-CODING RNAs AND MODULATION OF TH17 EFFECTOR FUNCTION
#372Methods of treating or preventing pruritis by blocking natriuretic polypeptide B
#373Method for detecting protein-protein interaction
#374Methods of identifying insect-TRPA1 modulators
#375IDENTIFICATION OF CXCR8, A NOVEL CHEMOKINE RECEPTOR
#376Blockade of CCL18 signaling via CCR6 as a therapeutic option in treating interstitial lung disease
#377Peptide mimotopes of claudin 18.2 and uses thereof
#378Methods for testing anti-thrombotic agents
#379Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
#380Use of antagonists of the interaction between HIV GP120 and α4β7 integrin
#381Modulators of ATP-binding cassette transporters
#382MODULATORS OF GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE PROTEINS
#383DRG11-RESPONSIVE (DRAGON) GENE AND USES THEREOF
#384Drug target site within GP120 of HIV
#385METHOD OF TREATING TUBERCULOSIS
#386Neuregulin variants and methods of screening and using thereof
#387Biomarker for MELK activity and methods of using same
#388COMPOSITIONS AND METHODS FOR TREATING IMMUNE AND VIRAL DISORDERS AND MODULATING PROTEIN-RNA INTERACTION
#389Modulation of T cell signaling threshold and T cell sensitivity to antigens
#390Fluorescent-HAP: a diagnostic stain for HBV cores in cells
#391Process for the identification of a compound which inhibits the binding of the first bromodomain of each of human BRD-2, BRD-3, and BRD-4
#392Assays for determining plasma kallikrein system biomarkers
#393PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE
#394Method for increasing interferon activity in an individual
#395Epidithiodioxopiperazine compound or its derivatives, and the use thereof
#396Soluble CD33 for treating myelodysplastic syndromes (MDS)
#397Methods for increasing DISC1 in a subject with schizophrenia or bipolar disorder by an antagonist inhibiting DISC1 binding to FBXW7
#398Compounds and methods for inhibiting Cif virulence factor
#399Method of treating pain with an antibody against netrin-4, Unc5B or neogenin
#400A high-throughput assay to identify molecules that modulate Rb-E2F binding
#401METHOD FOR SCREENING EMT INHIBITOR
#402Compositions and methods for increasing bone mineralization
#403SCREENING METHODS USING FYN IN COMBINATION WITH TAU PROTEIN
#404Therapeutic polynucleotides, compositions, and methods
#405Substituted piperazinyl acetohydrazide procaspase-activating compounds
#406Assays for BTK inhibitors
#407Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
#408METHOD OF INHIBITING BINDING OR ACTIVITY OF MIF BY ADMINISTERING A MIF ANTAGONIST
#409DOT1L probes
#410Method of screening for a compound for inhibitory activity of FN14-tweak interaction
#411Methods and compositions for modulating cancer stem cells
#412Camptothecin derivatives as anti-HIV agents and methods of identifying agents that disrupt Vif self-association
#413Inhibitors Of Fatty Acid Amide Hydrolase And Monoacylglycerol Lipase For Modulation Of Cannabinoid Receptors
#414RAGE AS A C1Q RECEPTOR, METHODS AND APPLICATIONS
#415NOVEL ASSAY
#416Treatment of brain derived neurotrophic factor (BDNF) related diseases by inhibition of natural antisense transcript to BDNF
#417Methods and materials for treating cancers that express reduced levels of wild-type p53 polypeptides
#418Detection of protein to protein interactions
#419METHODS FOR ASSAYING JAK2 ACTIVITY IN RED BLOOD CELLS AND USES THEREOF
#420Inhibitors of mitochondrial fission and methods of use thereof
#421THERAPIES FOR CARDIOMYOPATHY
#422Inflammatory disease treatment composition including anti-myosin regulatory light-chain polypeptide antibody
#423Immunomodulators
#424Screening assay for identification of poly(ADP-ribose) polymerase 1 inhibitors
#425CSN5 POLYPEPTIDES AND USES THEREOF FOR SCREENING THERAPEUTIC AGENTS
#426Use of antagonists of the interaction between HIV GP120 and α4β7 integrin
#427Peptide for inducing mast cell-specific apoptosis and use thereof
#428Energy drinks and other nutritional aids derived from agave-based spirits
#429Lamin A, an activator of longevity/anti-aging SIRT1 protein
#430Hydrolases, nucleic acids encoding them and methods for making and using them
#431FKBP52-Tau interaction as a novel therapeutical target for treating the neurological disorders involving Tau dysfunction
#432Enzymatic methods and enzymes
#433NMR ASSAY TO SCREEN PROTEIN-PROTEIN INTERACTION INHIBITORS
#434Method and kits for the diagnosis of influenza
#435Biological Materials and Uses Thereof
#436Assay and method for identifying compounds that reduce SIL1 expression or activity
#437FAM150A, FAM150B, AND FAM150 ANTAGONISTS AND USES THEREOF
#438Reagent for diagnosing tumor, pharmaceutical composition, and screening method
#439Polypeptides for treating and/or limiting influenza infection
#440Substances for treatment or relief of pain
#441MDL-1 ligand
#442Compositions and methods relating to hindering DOT1L recruitment by MLL-fusion proteins
#443RECEPTORS OF RSPO2 AND RSPO3
#444Rapid method to analyze ubiquitin-proteasome activity and to screen for ubiquitin-proteasome inhibitor
#445INHIBITION OF THE COMPLEMENT SYSTEM
#446Treatment of drug abuse by preventing GAPDH nitrosylation
#447Intracellular Phenotypic Screening
#448Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
#449ANIMAL MODEL WITH A FILAGGRIN GENE PROMOTER
#450Cyclic sulfonamides as sodium channel blockers
#451Cancer treatment and immune system regulation through FAT10 pathway inhibition
#452Identification of an inhibitor of iRhom1 or an inhibitor of iRhom2
#453Fragment ligated inhibitors selective for the polo box domain of PLK1
#454Antibiotic Peptides
#455Methods and compositions for enhanced immunological therapy and targeting of gram-positive bacteria
#456IDENTIFICATION OF MODULATORS OF BINDING PROPERTIES OF ANTIBODIES REACTIVE WITH A MEMBER OF THE INSULIN RECEPTOR FAMILY
#457Agents that modulate immune cell activation and methods of use thereof
#458Polypeptides and polypeptide constructs comprising single domain antibodies directed against von Willebrand factor
#459Development of HBV-and/or HDV-susceptible cells, cell lines and non-human animals
#460Composition and kit comprising piperazine derivatives and metformin, and use thereof in the treatment of diabetes
#461Method for crystallization of TRX-TXNIP complex mutein and 3D structure thereof
#462METHODS FOR DETERMINING RESISTANCE AGAINST MOLECULES TARGETING PROTEINS
#463Sweet taste receptor chimeric proteins and use thereof
#464Human Betacoronavirus lineage C and identification of N-terminal dipeptidyl peptidase as its virus receptor
#465TARGET INHIBITION MAP SYSTEM FOR COMBINATION THERAPY DESIGN AND METHODS OF USING SAME
#466DEVICES AND METHODS FOR SINGLE CELL ANALYSIS
#467Compounds and method for treating or preventing disease conditions associated with alpha-1-antitrypsin
#468Cell based sensor
#469Anti-MCAM Antibodies and Associated Methods of Use
#470Method for determining breast cancer treatment
#471Targets in multiple myeloma and other disorders
#472TREATMENT OF AUTOPHAGY-BASED DISORDERS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTIC AND SCREENING ASSAYS AND KITS
#473Methods for detecting LP-PLA2 activity and inhibition of LP-PLA2 activity
#474Methods and compositions for treating alzheimer's disease
#475LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS
#476IRHOM2 INHIBITION FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS
#477DETECTION AND MODULATION OF CYTOCHROME C ACETYLATION
#478Assays and Cell-Based Tests Using a Receptor Na/K-ATPase/Src Complex and Uses Thereof
#479Modulation of activity of neurotrophins
#480TFPI inhibitors and methods of use
#481Multiprotein assemblies
#482Method for identifying compounds of therapeutic interest
#483METHODS FOR IDENTIFYING ANTI-CANCER COMPOUNDS
#484Mutations In Calmodulin Genes
#485Method for designing a drug regime for HIV-infected patients
#486Methods and compositions for modulating G-alpha-Q signaling
#487Method of screening anti-plasmodial activity of acriflavin and acriflavin as an anti-malarial agent
#488ANTICOAGULANT ANTIDOTES
#489THERAPEUTIC AND DIAGNOSTIC TARGET
#490Enzyme-activating compounds and compositions
#491COMPOSITIONS AND METHODS FOR MODULATION OF IL-20 FAMILY CYTOKINE ACTIVITY
#492Composition comprising material for inhibiting SCF or receptor thereof for treating or preventing diseases associated with vascular permeability
#493Complement split product C4d for the treatment of inflammatory conditions
#494Diagnostic and screening methods for atopic dermatitis
#495PTPRS AND PROTEOGLYCANS IN AUTOIMMUNE DISEASE
#496B7 family member zB7H6 and related compositions and methods
#497BIOORTHOGONAL CHEMICAL INDUCERS OF REVERSIBLE DIMERIZATION FOR CONTROL OF PROTEIN FUNCTION IN CELLS
#498Methods and compounds for increasing threonyl-tRNA synthetase activity
#499COMPOSITIONS AND METHOD FOR DETERMINING THE EFFICACY OF AMYLOIDOSIS TREATMENTS
#500COMPOSITIONS AND METHODS FOR TREATMENT
#501Selective inhibitors of undifferentiated cells
#502BIOLUMINESCENCE IMAGING-BASED SCREENING ASSAY AND INHIBITORS OF ABCG2
#503Methods and compositions for the treatment of β-thalassemia
#504COMPOSITIONS AND METHODS FOR TREATMENT
#505COMPOSITIONS AND METHODS FOR TREATMENT
#506COMPOSITIONS AND METHODS FOR TREATMENT
#507COMPOSITIONS AND METHODS FOR TREATMENT
#508COMPOSITIONS AND METHODS FOR TREATMENT
#509COMPOSITIONS AND METHODS FOR TREATMENT
#510COMPOSITIONS AND METHODS FOR TREATMENT
#511Pregnancy-associated plasma protein-A2 (PAPP-A2) polypeptides
#512Biomarker for determining mitochondrial damage in friedreich's ataxia
#513AMPK activator screening method, and AMPK activator
#514BIOMARKER
#515Modulators of ATP-Binding Cassette Transporters
#516Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide phosphodiesterases
#517Assay for identification of therapeutics targeting ternary complex formation in protein synthesis
#518Anti-FcRn antibodies
#519Conformational-specific antibodies against A[β] oligomers
#520Methods of treating a meiotic kinesin-associated disease
#521Fluorescent neutralization and adherence inhibition assays
#522CD147 as receptor for pilus-mediated adhesion of to vascular endothelia
#523Compositions and methods for treating B-lymphoid malignancies
#524METHODS FOR DETERMINING THE EFFECTS OF COMPOUNDS ON JAK/STAT ACTIVITY
#525Polypeptide fragments comprising endonuclease activity and their use
#526Compositions and methods for the diagnosis and treatment of tumor
#527COMPOSITIONS AND METHODS FOR INHIBITING RESOLVASES
#528METHODS FOR THE SCREENING OF ANTIBACTERIAL SUBSTANCES
#529NOVEL INTEGRIN alpha9 beta1 LIGAND AND USES THEREOF
#530Compositions and methods related to protein displacement therapy for myotonic distrophy
#531MENA AND ALPHA5 INTEGRIN INTERACTION
#532BIOMARKERS FOR CANCER CHARACTERIZATION AND TREATMENT
#533Polypeptides containing a modified fragment of the peptide IF1
#534DNA controlling miR-140 expression, and screening method of drugs using said DNA
#535Methods for Screening Inhibitors of Tau Phosphorylation By Casein Kinase I
#536MTK1-ACTIN INHIBITORS AND METHODS OF USE
#537COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR
#538METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF TH2 MEDIATED DISEASES
#539Method to prevent cancer metastasis and inhibit inflammation by inhibition of p68 interaction with calmodulin
#540Histamine-releasing factor (HRF), HRF-receptor and methods of modulating inflammation
#541Modulating the interaction between ZO-2/TJP2 and a Snail zinc finger transcription factor family member
#542Method of blocking vascular leakage using an anti-ANG2 antibody
#543Anti-Ang2 antibody
#544Methods of Identifying Modulators of Dephosphorylation of Histone Deacetylase
#545METHOD FOR SELECTIVELY QUANTIFYING A-BETA AGGREGATES
#546Modulation of activity of proneurotrophins
#547Theranostics platform and methods of use
#548ASSAY AND METHOD FOR IDENTIFYING COMPOUNDS THAT INHIBIT EXCITOTOXIC SIGNALS
#549Assay, composition and non-enzymatic mechanism of statin in modulating lipid metabolism
#550Membrane span-kinase fusion protein and the uses thereof
#551METHODS FOR ASSAYING PROTEIN-PROTEIN INTERACTIONS
#552Method of identifying a compound for treating a hypoxic or ischemic related disorder
#553Catalytic Tagging System to Study Macro-Molecular Interactions Using Engineered Ubiquitin Ligase and Ubiquitin-Like Proteins to Facilitate Substrate Identification
#554Modulation of T cell signaling threshold and T cell sensitivity to antigens
#555INHIBITION OF PATTERN RECOGNITION RECEPTORS IN PANCREATIC CANCER TREATMENT USING TLR INHIBITORS
#556Biosensor for detecting RAF/KSR family kinase dimerization and uses thereof
#557Method for identifying bromodomain inhibitors
#558Protease deubiquitinating inhibitor screening
#559Stabilized antiviral fusion helices
#560METHOD FOR THE IDENTIFICATION OF BETA-SHEET AGGREGATED PROTEIN LIGANDS
#561Therapeutic approach for polyglutamine degeneration
#562Tools and methods for expression of membrane proteins
#563HISTONE DEACETYLASE (HDAC) BIOMARKERS IN MULTIPLE MYELOMA
#564PROGNOSTIC, SCREENING AND TREATMENT METHODS AND AGENTS FOR TREATMENT OF METSTASIS AND INFLAMMATION USING T54 ONCOFOETAL GLYCOPROTEIN
#565Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide phosphodiesterases
#566Real-time analysis for cross-linked peptides
#567Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
#568COMPOSITIONS AND METHODS FOR SCREENING AND TREATMENT OF STURGE-WEBER SYNDROME, KLIPPEL-TRENAUNAY-WEBER SYNDROME, AND PORT-WINE STAINS (PWSS)
#569Screening methods of BMP/GDF signaling modulators using DRG11-responsive (DRAGON) proteins
#570METHOD FOR DETECTING COMPOUND-BINDING PROTEIN
#571Method for detecting protein-protein interaction
#572PHYTOPHTHORA PHOSPHOLIPASE C
#573Nicotinamide adenine dinucleotide gene encoding fluorescent probe, preparation method therefor and application thereof
#574Treatment of cancer by inhibition of the MYD88/ERK MAP kinase interaction
#575Fluorogenic Peptide Probes and Assays
#576Method for identifying modulators of ubiquitin ligases
#577Botulinum Neurotoxin E Receptors and Uses Thereof
#578Method of treating endometriosis
#579Cyclin based inhibitors of CDK2 and CDK4
#580Chaperone interaction assays and uses thereof
#581DRUG SCREENING AND POTENCY ASSAYS
#582Methods of identifying SENP1 inhibitors
#583Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
#584Autoimmune and inflammatory disorder therapy
#585Binding domains directed against GPCR:G protein complexes and uses derived thereof
#586Serology assays
#587Cell-based methods for coupling protein interactions and binding molecule selection
#588Compositions and methods for the treatment of norovirus infection
#589MDL-1 LIGAND
#590Method for screening an agent preventing or treating cancer using glycyl-tRNA synthetase and cadherin
#591Selective glycosidase inhibitors and uses thereof
#592RNA-YY1 interactions
#593Screening method for therapeutic agent for chondropathy and modified chondrocyte for treatment of chondropathy
#594Methods and compositions for enhancing proteasome activity
#595Methods for selecting protease resistant polypeptides
#596Inhibitors of viral integrase and methods of use
#597Methods and compositions for detecting and modulating O-glycosylation
#598Method of inhibiting binding or activity of MIF by administering a MIF antagonist
#599ERAP1-derived peptide and use thereof
#600Compositions and methods for treatment