SYSTEMS AND METHODS FOR THE ASSESSMENT OF G-PROTEIN ACTIVATION

Modifiable Chemical Inducers of Proximity and Methods of Using the Same

Signaling conjugates and methods of use

Enzyme quantification

ENZYME QUANTIFICATION

Detection kit and method for detecting abused drugs

Quencher and use thereof

Bis-acetal-based substrates for imaging exo-glycosidase activity

Assays for nucleosome remodeling activity

Assays for detecting analytes in samples and kits and compositions related thereto

Detection method using fibrous substance

Polymer dye modification and applications

NOVEL ANTIBODY CONJUGATES SUITABLE FOR USE IN DISCRETE FLUORESCENCE QUENCHING DISPLACEMENT IMMUNOASSAYS

BENZAMIDE INHIBITORS OF BACTERIAL LIPOPROTEIN SIGNAL PEPTIDASE

Optical analyses of particles and vesicles

Modified-dextrans for use in optical glucose assays

Reactive peptide labeling

Nanomaterial-based bacterial sensors

Assay for determining antibody or ligand binding and function

Biosensor based on a tethered particle

Method for detecting and/or characterizing the interaction between proteins and small molecules

Real time western blot assays utilizing fluorescence resonance energy transfer (FRET)

Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence

Reporting constructs for characterization of neurotoxins

Methods and systems for detecting an analyte or classifying a sample

Chemical sensor kit and analysis method

High-Throughput Aptamer Screening Assay

KITS, METHODS AND THEIR USES FOR DETECTING CELL-CELL INTERACTIONS IN A SAMPLE KITS

Bacteriophage-based electrochemical biosensor

THIENOPYRROLE COMPOUNDS AND USES THEREOF

Fluorescent fusion proteins for use as reporters in multiplexed bioassays

SUBSTRATES RECOGNIZED BY FIBROBLAST ACTIVATION PROTEIN (FAP) AND METHODS OF USING THE SAME

Reporter protein fused antibodies

METHODS OF ASSESSING PROTEIN INTERACTIONS BETWEEN CELLS

Biosensor based on capture molecules with different affinities

Compositions and methods for allergen detection

METHOD AND APPARATUS FOR DETECTING AN ANALYTE

Fluorescent methods and materials for directed biomarker signal amplification

Light harvesting multichromophore compositions and methods of using the same

Kit for detecting antigen or measuring its amount

Multiplexed catalyzed reporter deposition

Methods for detecting multiple nucleic acids in a sample using reporter compounds and binding members thereof

Helical polycarbodiimide polymers and associated imaging, diagnostic, and therapeutic methods

System and method for identifying the presence of insects

Protein kinase allostery sensor and methods of making and using same

Intrabodies targeting post-translational modifications of native proteins and method for obtaining them

ANTI-PD-L1 ANTIBODY TREATMENT OF BLADDER CANCER

Fluorescent fusion polypeptide capable of detecting phosphorylation of cellular membrane receptors by GRKs (G-protein receptor kinases) and/or receptor tyrosine kinases (RTKs)

HIGH PRECISION SPECTRAL FRET ASSAYS

Nucleic acid nanoswitch construction methods

Breath analyte sensing apparatus that generates gas streams that flow over a nanoparticle-based sensor

Process for determining enzyme activity in a cell by activity-based reporter gene technology (ABRGT)

Nanoluc suicide substrates

Sample clarification and reduction of background fluorescence for fluorescent detection of analytes

Systems and methods for high-resolution imaging

CRYPTATES AND METHODS OF USE

In vitro and cell based assays for measuring the activity of botulinum neurotoxins

Kinase and/or phosphatase sensing via hydroxyquinoline-sensitized chelates

Allosteric split trehalase biosensor

ILT3 ligand

METHOD FOR OPTIMIZING FLUORESCENCE-BASED DETECTION

Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens

Molecular sensors

GENERATION OF PEPTIDES

Devices, Compositions, and Methods for Measuring Molecules and Forces

Co-incubating confined microbial communities

Dual-reporter electrochemical sensors with drift correction

Detection of analytes using metal nanoparticle probes and dynamic light scattering

Microbial-based biosensors

IMPROVED PHARMACOKINETIC ASSAYS FOR IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

Deep ultraviolet-excitable water-solvated polymeric dyes

Validation methods for multiplexed imaging method

Cytoplasmic protein complex comprising a kinase substrate sensor, cells comprising the complex, and associated detection methods

FLUORESCENT DETECTOR SYSTEMS FOR THE DETECTION OF CHEMICAL PERTURBATIONS IN STERILE STORAGE DEVICES

HETEROGENEOUS LUMINESCENT OXYGEN CHANNELING IMMUNOASSAYS AND METHODS OF PRODUCTION AND USE THEREOF

Method for photobleaching stained cells

Universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples

METHODS AND SYSTEMS FOR SPECIES-ON-SPECIES IMMUNOASSAY DETECTION

Polymeric BODIPY dyes and methods for using the same

Non-FRET cell based assay

Compositions and methods for identifying, quantifying, and/or characterizing an analyte

Methods and devices for detection of peripheral membrane protein interactions using nonlinear optical techniques

Regulating electron flow using fragmented proteins

FRET-based glucose-detection molecules

Methods and compositions for backscattering interferometry

Methods for the treatment of cardiac hypertrophy

DNA ink—near-field absorption coupling for colorimetric detection, DNA ink, chromic photoswitches, and chromic molecular ruler

Sensor apparatus and method for testing a sample

DETECTION OF ALLERGEN EXPOSURE

Enzyme quantification

Decoding methods for multiplexing assays and associated fluidic devices, kits, and solid supports

Material and method to screen proteasome stimulators

ASSAYS FOR MEASURING BINDING KINETICS AND BINDING CAPACITY OF ACCEPTORS FOR LIPOPHILIC OR AMPHIPHILIC MOLECULES

Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer

Methods of assessing protein interactions between cells

Fluorescent supramolecular biosensor and preparation method thereof

Multiplexed single molecule RNA visualization with a two-probe proximity ligation system

Method for determining kinetic profiles in drug discovery

Fluorescent methods and materials for directed biomarker signal amplification

Fret-labeled compounds and uses therefor

3D-exoquant method for the analysis of surface molecules and quantification of tissue-specific exosomes in biological fluids

Light harvesting multichromophore compositions and methods of using the same

Method for determining the quantity of an HbA1c in a blood sample

SIGNALING CONJUGATES AND METHODS OF USE

High throughput optical assay of human mixed cell population spheroids

Method of detecting analyte in a sample with binding reagent, first detection reagent, and second detection reagent

A method of determining the abundance of a target molecule in a sample

Methods, compositions, and kits for detection of bacterial proteases

Calcium indicator polypeptides and methods of use thereof

Polymeric dye ratiometric sensor for analyte detection and methods of using the same

Janus particle, tetrahedral structure including Janus particles, method of fabricating Janus particles, and method of detecting biomolecules

Lactate biosensors and uses thereof

NANOPORE-BASED ANALYSIS OF COMPOUNDS USING MOBILE FRET PAIRS

Cell based assay for determining antibody or ligand binding and function

Sensor for infrared communication using plant nanobionics

Microfluidic devices and methods of use in the formation and control of nanoreactors

Methods to spatially profile protease activity in tissue and sections

Signaling conjugates and methods of use

Formation and use of embedded solutions in nanoscale materials

Cellular based fret assay for the determination of simultaneous binding

Genetically encoded potassium ion indicators

Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential

Immunofluorescence assays

Medical Toilet with Aptamer Sensors to Analyze Urine

Activation of bioluminescence by structural complementation

Using a blue-shifted reference dye in an optical glucose assay

Activation of bioluminescence by structural complementation

Simultaneous measurement of halide ion concentration and pH

High-throughput fluorescence polarization microorganism screening assay

Method for measuring tyrosine phosphatase and tyrosine kinase activity

Methods for measuring binding and cellular engagement of ligands with target proteins

ANALYTE DETECTION

Probes and assays for measuring E3 ligase activity

Compositions and methods for improved neurotoxin assays

PH-responsive proteolysis probe

In vivo detection of phospholipase activation

HIGH PRECISION SPECTRAL FRET ASSAYS

ISOLATION OF ANTIGEN SPECIFIC B-CELLS

Digital immunoassay

Automatic analysis device, automatic analysis system, and automatic analysis method

Substituted triazenes protected from degradation by carboxylation of N1

Methods for measuring small molecule affinity to cereblon

Method for measuring in vivo inhibition of intracellular RNase

DRUG DISCOVERY AND PROTEIN-PROTEIN INTERACTION ASSAY USING FLUORESCENT PROTEIN EXCHANGE

PROTEIN-PROTEIN INTERACTION DETECTION SYSTEMS AND METHODS OF USE THEREOF

Methods and reagents for determining immunoglobulin gamma (IgG) antibody isotype concentration from biological samples

Activation of bioluminescence by structural complementation

QUANTITATIVE FRET-BASED INTERACTION ASSAY

Protein proximity assay in formalin fixed paffafin embedded tissue using caged haptens

Apparatus and method for improved molecular detection

Target-binding activated split reporter systems for analyte detection and related components and methods

Methods of modifying a target nucleic acid with an Argonaute

Methods for detecting protein-protein interactions

Aptasensor for detecting female-specific trace of blood and detection apparatus using the same

Method to detect activity of a polymerase

Immunological Testing

SYNAPTIC VESICLE CYCLING ASSAYS AND SYSTEMS

Rapid and high-sensitive bacteria detection

Compositions and methods for allergen detection

Molecular probe for signal amplification and kit and assay using the same

OPTICAL METHOD FOR DETECTING VIABLE CELLS IN A CELL SAMPLE

Proximity based methods for selection of binding partners

Sensor systems for target ligands and uses thereof

IMMUNOASSAY METHOD AND ASSAY REAGENT USED IN SAID METHOD

Method of determining the presence and/or amount of target molecules

Exonuclease enabled proximity extension assays

Linked Peptide Fluorogenic Biosensors

Activation of bioluminescence by structural complementation

Photoactivatable antimicrobial agents and therapeutic and diagnostic methods of using same

Sensors, methods and kits for detecting nicotinamide adenine dinucleotides

Microfluidic devices and methods of use in the formation and control of nanoreactors

Fluorescent methods and materials for directed biomarker signal amplification

Red-shifted luciferase-luciferin pairs for enhanced bioluminescence

Breath analyte sensing apparatus that generates gas streams that #flow over a nanoparticle-based sensor

Photoluminescent nanoparticles and their uses in detection or quantification of singlet oxygen

NOVEL VOLTAGE-DEPENDENT ION CHANNEL FUSIONS AND METHOD OF USE THEREOF

Molecular biosensors capable of signal amplification

Universal assay for determining the quantity of TNFα inhibitory drugs and their corresponding anti-drug-antibodies

Method for preparing a biological sample for use in an immunolabeling process

IMMUNOGLOBULIN ASSAYS USING NANOPARTICLES

METHOD FOR THE FORMATION AND USE OF AN IMMUNOLABELING COMPLEX

MOLECULAR SENSORS

HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS

Co-binder assisted assay methods

Biosensor based on a tethered particle

Phosphatase or kinase activity detection composition and detection method

Methods and systems for analyzing a sample with a construct comprising a fluorescent moiety and a magnetic moiety

Polymeric BODIPY dyes and methods for using the same

Plasmonic biosensor based on molecular conformation

Polymer-nanostructure composition for selective molecular recognition

SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS AND PROCESS FOR MAKING AND USING SUCH PROBES

Biosensor

Photoinduced electron transfer voltage-sensitive compounds

METHODS FOR BLOOD TYPING AND ANTIBODY SCREENING

Dynamic switching biosensor

BIMOLECULAR AUTOINHIBITED BIOSENSOR

Fluorescent probes for monitoring voltage by photo-induced electron transfer

Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence

Resonance energy transfer assay with cleavage sequence and spacer

Biosensor for detecting multiple epitopes on a target

Apparatus and method for controllably populating a channel with charge carriers

Devices and methods useful for detecting mechanical forces of ligand receptor interactions

Proximity assays using chemical ligation and hapten transfer

METHOD FOR THE DETECTION OF ANTIGEN PRESENTATION

Composition for enzyme immunoassay using immunofluorescence and uses thereof

SPFS biosensor based on nucleic acid ligand structural change

High-throughput screening for compounds modulating expression of cellular macromolecules

DNA-linked enzyme-coupled assays

METHOD FOR DETECTING A SPATIAL PROXIMITY OF A FIRST AND A SECOND EPITOPE

Biosensor based on Gβγ-interacting proteins to monitor G-protein activation

Oligonucleotide-based probes for detection of bacterial nucleases

Photoactivatable voltage sensitive dyes

LSPR-based high sensitivity aptamer sensor using intercalation agent

Optical molecular nanowire sensor

Unfolding Proximity Probes and Methods for the Use Thereof

Multi component detection

Yeast-based biosensor

Fluorescent AMP-kinase biosensors

Antibody-based arrays for detecting multiple signal transducers in rare circulating cells

LUMINESCENT OXYGEN CHANNELING IMMUNOASSAY UTILIZING THREE ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF

A Method of Measuring Antibody Concentration in a Sample

Substrates for detection of botulinum neurotoxin

SmFRET with membrane proteins

Enzyme quantification

Nucleosome substrate assays

Methods of measuring factor D activity and potency of factor D inhibitors

Methodologies for measuring isopeptidase activity in biological samples in a high throughput manner

Fluorescent methods and materials for directed biomarker signal amplification

Genetically encoded histone reporter allele constructs

Assays for detecting analytes in samples and kits and compositions related thereto

Dissolution-enhanced time-resolved fluoroimmunoassay based on rare earth nanomaterial

Light polarization analyzer

FLUORESCENT TWO-HYBRID (F2H) ASSAY FOR DIRECT VISUALIZATION OF PROTEIN INTERACTIONS IN LIVING CELLS

Protein L based bioassay method for determining presence of soluble antibodies in a sample and kit therefor

Microfluidic devices and methods of use in the formation and control of nanoreactors

Development of Sensitive FRET Sensors and Methods of Using the Same

NANOSENSOR FOR ASSESSING THROMBIN INHIBITORS

Steric-hindrance hybridization systems, assays and methods associated thereto

Optical analyses of particles and vesicles

Complex for detecting target material and method of detecting target material using the same

Systems and methods for the monitoring of protein complex formation in cells

Method for detecting protein-protein interaction

Sensor

Thienopyrrole compounds and uses thereof

PAPER-BASED IMMUNOASSAY WITH POLYMERIZATION-BASED SIGNAL AMPLIFICATION

Methods and Compositions for Detecting Botulinum Neurotoxin

METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEIN

Cell penetrating protein adaptor molecules and their application in research and medicine

Light harvesting multichromophore compositions and methods of using the same

Method for assaying a protease

Carboxy X rhodamine analogs

Methods for determining protein structure using a surface-selective nonlinear optical technique

Method of determining temperature and method of detecting a target peptide

REAGENT SYSTEM AND METHOD FOR MODIFYING THE LUMINESCENCE OF LANTHANIDE (III) MACROCYCLIC COMPLEXES

Biochemical markers for CVD risk assessment

Activation of bioluminescence by structural complementation

Assays for measuring binding kinetics and binding capacity of acceptors for lipophilic or amphiphilic molecules

Genetically encoded fluorescent sensors for detecting ligand bias and intracellular signaling through cAMP pathways

Detection and quantification of polymeric analytes using fluorescent lanthanide detection not relying on charge transfer from polymer aromatic groups

Fluorescent methods and materials for directed biomarker signal amplification

Methods and compositions for backscattering interferometry

Polymeric BODIPY dyes and methods for using the same

Volume response sensors having analyte controlled reversible crosslinking

Homogenous immunoassay with compensation for background signal

Human trypsinogen with reduced autoactivation and its use in an immunoassay

Bimolecular protease-based biosensor

PLASMONIC BEADS FOR MULTIPLEXED ANALYSIS BY FLOW DETECTION SYSTEMS

Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices

DEVICE FOR DETECTING AN ANALYTE

Genetically encoded probe for quantification of pyruvate concentration and methods of using the same

Fluorescent molecular rotors

Genetically encoded FRET-based MMP-9 activity biosensor and use thereof

Cell detection with conjugates having an enzymatically releasable detection moiety

Resonance energy transfer assay with cleavage sequence and spacer

Detection of analytes using metal nanoparticle probes and dynamic light scattering

Fluorogenic/fluorescent probes derivative from sulfoxanthene, and use thereof

Means and methods for bioluminescence resonance energy transfer (BRET) analysis in a biological sample

Fluorescence sensor for target analysis, kit for target analysis, and target analysis method using same

Co-incubating confined microbial communities

Thermally resolved molecule assays

Screening for inhibitors of ribosome biogenesis

Compounds useful for FRET and methods related thereto

Self-assembled peptide nanostructures by exploiting conformational change, biosensor using the same and detection method of biomolecules using the same

Molecular biosensors with a modular design

Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence

Probes and assays for measuring E3 ligase activity

Botulinum assay with synaptobrevin substrate moiety

Homogenous thermal shift ligand binding assay

System and method for iterative detection of biological molecules

Methods and apparatus for monitoring interactions between particles and molecules using nanophotonic trapping

Linked Peptide Fluorogenic Biosensors

Luminescent oxygen channeling immunoassays utilizing electrochemical discharge of singlet oxygen and methods of production and use thereof

Method and devices for discharging contaminants out of a seal chamber

Methods and systems for enhanced microfluidic processing

Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity

HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS

Real-time analytical methods and systems

CDKACT BIOSENSORS-FLUORESCENT POLYPEPTIDE TO PROBE THE ACTIVITY OF CDK/CYCLIN KINASES IN VITRO, IN CELLULO AND IN VIVO

Substituted imidazo[1,2-A]pyrazines for measuring a transcription activity

Method for in vitro detection and monitoring of a disease by measuring disease-associated protease activity in extracellular vesicles