Cyanochrome fluorophores

CASPASE IMAGING PROBES

Three-component biosensors for detecting macromolecules and other analytes

Reducing optical interference in a fluidic device

HOMOGENEOUS IN VITRO FEC ASSAYS AND COMPONENTS

Carrier for analysis of an analyte and process for producing the same

Detection of analtyes using metal nanoparticle probes and dynamic light scattering

γ-Secretase substrates and methods of use

FRET-based binding assay

FLUORESCENT TWO-HYBRID (F2H) ASSAY FOR DIRECT VISUALIZATION OF PROTEIN INTERACTIONS IN LIVING CELLS

HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM

Fret assays, methods for performing the assays and compounds relevant to the assays

METHOD AND SYSTEM FOR MEASURING MEMBRANE POTENTIAL BASED ON FLUORESCENCE POLARIZATION

PEPTIDE CONJUGATES AND FLUORESCENCE DETECTION METHODS FOR INTRACELLULAR CASPASE ASSAY

NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS

Single molecule-format bioluminescent probe

Misfolded protein sensor method

Solution phase homogeneous assays

Method and apparatus for forming a homeostatic loop employing an aptamer biosensor

In vivo screen using chemical inducers of dimerization

Compounds and methods of use thereof for assaying lysophospholipase D activity

FRET-labeled compounds and uses therefor

Aggregation sensor and solutions and kits comprising the same

Multi-acceptor molecular probes and applications thereof

METHOD FOR MEASUREMENT OF CONCENTRATION OF ANTIGEN

Conjugates, and use thereof in detection methods

Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof

Nonseparation Assay Methods Using Peroxide Generating Enzymes

THYROTROPIN RELEASING HORMONE RECEPTOR-OREXIN RECEPTOR HETERO-DIMERS/-OLIGOMERS

Method for determining the presence of an enzyme in a sample

Fluorescently labeled fusion protein for assaying adenosine triphosphate

TUNABLE AFFINITY LIGANDS FOR THE SEPARATION AND DETECTION OF TARGET SUBSTANCES

CONFORMATIONALLY DYNAMIC PEPTIDES

Nanoprobes for detection or modification of molecules

STOCHASTIC CONFINEMENT TO DETECT, MANIPULATE, AND UTILIZE MOLECULES AND ORGANISMS

Semiconductor nanocrystal probes for biological applications and process for making and using such probes

Biosensors to measure InsP3 concentration in living cells

Bimolecular Constructs

METHOD FOR CARRYING OUT AND EVALUATING MIX & MEASURE ASSAYS FOR THE MEASUREMENT OF REACTION KINETICS, CONCENTRATIONS AND AFFINITIES OF ANALYTES IN MULTIPLEX FORMAT

Fluorescent phospholipase Aindicators

Generic kinase/phosphatase assay with single readout

Polymerized conjugates for biological applications

Intracellular reporters

NANOSCOPIC BIOMOLECULAR ABSORPTION SPECTROSCOPY ENABLED BY SINGLE NANOPARTICLE PLASMON RESONANCE ENERGY TRANSFER

Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity

Method for measuring bonding activity of antibody which mimics antibody-dependent cell medicated cytotoxic activity

Synthetic cell platforms and methods of use thereof

Quinolone based compounds exhibiting, prolyl hydroxylase inhibitory activity, and compositions, and uses thereof

METHODS FOR MEASURING ENZYME ACTIVITY

Assay particles and methods of use

Nucleic acid modules for expression and tagging of membrane proteins and methods of use

Ligand-regulable transactivation systems, methods of use thereof, methods of detecting estrogen receptor ligands, and methods of differentiating estrogen receptor ligand agonists and antagonists

BIOSENSORS, METHOD FOR OBTAINING THE SAME AND USES THEREOF

RECEPTOR FAMILY PROFILING

Multi-wavelength analyses of sol-particle specific binding assays

Semiconductor nanocrystal probes for biological applications and process for making and using such probes

RAPID HOMOGENEOUS DIAGNOSTIC TESTING PLATFORM BASED ON LANTHANIDE FLUORESCENT RESONANCE ENERGY TRANSFER

Kinase and ubiquination assays

Cell-signaling assays

Protein detecting device

METHOD OF DETECTION

ASSAY METHODS FOR IDENTIFYING AGENTS THAT MODIFY THE ACTIVITY OF NAPE-PLD OR Abh4

Methods of Reducing Repeat-Induced Silencing of Transgene Expression and Improved Fluorescent Biosensors

Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors

Cyanine dyes

METHOD FOR THE DETECTION OF AMYLOID-B OLIGOMERS IN BODY FLUIDS

METHOD FOR HIGH SPATIAL RESOLUTION EXAMINATION OF A SAMPLE STRUCTURE LABELED WITH A SUBSTANCE

METHOD FOR DETECTING INTERACTIONS BETWEEN TWO AND MORE BIOLOGICAL MACROMOLECULES

GPCR Arrestin Assays

Sequential analysis of biological samples

LIGAND-CONTAINING MICELLES AND USES THEREOF

Methods for determining active ingredients in pro-drug PEG protein conjugates with releasable PEG reagents (in vitro de-pegylation)

RAPID DETECTION NANOSENSORS FOR BIOLOGICAL PATHOGENS

Chromatography quantitative measuring apparatus

Chromatography quantitative measuring apparatus

Chromatography quantitative measuring apparatus

Chromatography quantitative measuring apparatus

Method for the detection of post-translational modifications

Homogeneous luminescence bioassay

Methods and devices for detecting binding events via zeta-potential and pharmacologically active compounds and delivery systems identified thereby

High-content and high throughput assays for identification of lipid-regulating pathways, and novel therapeutic agents for lipid disorders

In vivo library-versus-library selection of optimized protein-protein interactions

Ion channel assay methods

FLUORESCENCE POLARIZATION ASSAYS FOR DETERMINING CLOSTRIDIAL TOXIN ACTIVITY

FLUORESCENCE POLARIZATION ASSAYS FOR DETERMINING CLOSTRIDIAL TOXIN ACTIVITY

Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith

METHODS OF GENERATING FLORESCENCE RESONANCE ENERGY TRANSFER (FRET) BETWEEN SEMICONDUCTOR QUANTUM DOTS AND FLUORESCENT DYES/PROTEINS VIA MULTI-PHOTON EXCITATION, ACHIEVING ZERO BACKGROUND OR DIRECT EXCITATION CONTRIBUTIONS TO THE FRET SIGNATURE

ASSAY SYSTEM FOR ADENOSINE TRIPHOSPHATE AND CREATINE KINASE

Luminescence assay using macrocyclic lanthanide (III) complexes

Sequential analysis of biological samples

PROTEIN INTERACTION REPORTER AGENTS AND METHODS FOR USING SAME

Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof

Amelioration of Inflammatory Arthritis By Targeting the Pre-ligand Assembly Domain (Plad) of Tumor Necrosis Factor Receptors

PESTICIDE BIOMARKER

DEEPLY QUENCHED ENZYME SENSORS AND BINDING SENSORS

Biological targeting compositions and methods of using the same

Detection of Analytes Using Reorganization Energy

Development of sensitive FRET sensors and methods of using the same

Homogeneous time resolved fluorescence based test system for

Method for identifying modulators of the NRF2-KEAP1-AREP pathway

FLUOROGENIC HOMOGENEOUS BINDING ASSAY METHODS AND COMPOSITIONS

Inorganic phosphate assays

Methods and compositions for pathogen detection using nanoparticle-fluorescent polymer complexes

Dark quenchers for donor-acceptor energy transfer

Method for analyte detection using proximity probes

Detection system and uses therefor

METHOD FOR DETERMINING TRANSPORT ACTIVITY OF A TRANSPORT PROTEIN

IMMOBILISATION OF FLUORESCENT PROTEINS

MULTIPLE LABELLING FOR ANALYTE DETECTION

HOMO-DOUBLY LABELED COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES

Membrane-Based Assay Devices that Utilize Time-Resolved Fluorescence

Methods and compositions for detecting neoplastic cells

Method and probes for the detection of a tumor-specific fusion protein

METHOD AND A MICRODEVICE FOR THE IDENTIFICATION AND/OR QUANTIFICATION OF AN ANALYTE IN A BIOLOGICAL SAMPLE

Methods and compositions related to the modulation of riboswitches

QUANTITATIVE MEASUREMENT METHOD FOR RECOMBINANT PROTEIN

Biosensors for monitoring receptor-mediated G-protein activation

Method for detecting and analyzing protein interactions in-vivo

Screening method for GPCR ligands

Rigidized trimethine cyanine dyes

NANO-SCALE FLUORO-BIOSENSORS EXHIBITING A LOW FALSE ALARM RATE FOR RAPID DETECTION OF BIOLOGICAL CONTAMINANTS

Single-molecule-format probe and utilization thereof

Compositions and methods for detection of small molecules using dyes derivatized with analyte responsive receptors in a chemiluminescent assay

Identification of substances that inhibit NEMO oligomerization

E3-INDEPENDENT UBIQUITINYLATION ASSAY

Ubiquitin Ligase Assays And Related Reagents

Devices for the detection of the presence and/or activity of proteases in biological samples

Detection systems utilizing supported lipid bilayers

Semiconductor nanocrystal probes for biological applications and process for making and using such probes

FLUORESCENT PROCHELATORS FOR CELLULAR IRON DETECTION

Ion channel assay methods

Three part assay for kinase or phosphatase activity

Annexin-based apoptosis markers

QUANTIFICATION AND AFFINITY CHARACTERIZATION OF ANTIBODIES FOR THE DIAGNOSIS OF DISEASE USING OPTICAL DIFFRACTION

Fluorescence Resonance Energy Transfer Assay Based on Modified Solid Surface

Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes

Fluorescent sensor based on two fluorescent moieties one of which is a semiconductor nanocrystal and methods of using and making

Method of revealing a biological process using a FRET measurement

Electrochemical sensor

Method for detecting intracellular interaction between biomolecules

Analyte detection using barcoded polymers

Luminescence biotin-transition metal complex conjugate, and method of amplifying signal using the same

Probe for detection and quantification of inositol-1,4,5-trisphosphate and a method for detecting and quantifying inositol-1,4,5-trisphosphate using the same

Alternate labeling strategies for single molecule sequencing

IDENTIFICATION OF MOLECULAR INTERACTIONS AND THERAPEUTIC USES THEREOF

Methods and materials for amplification of a signal in an immunoassay

FLUORESCENT PROTEINS WITH INCREASED PHOTOSTABILITY

Semiconductor nanocrystal probes for biological applications and process for making and using such probes

Luminescent Metal Oxide Films

Methods of producing competitive aptamer fret reagents and assays

Fluorescent assay

Methods for detection of botulinum neurotoxin

Fluorescent protein

METHODS FOR DETECTION OF CYCLOSPORIN A

High-Throughput Screening of Enantiomeric Excess (EE)

BLADDER CANCER TREATMENT AND METHODS

Photon reducing agents for fluorescence assays

Method for suppressing a FRET signal, FRET signal suppressor agents and use in a method for multiplexing biological events

Methods and compositions for use in analyte detection using proximity probes

FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES

Measuring receptor homodimerization

Optical determination of glucose utilizing boronic acid adducts

Optical determination of glucose utilizing boronic acid adducts

UNIVERSAL FLUORESCENT SENSORS

Methods, kits, and compositions for detecting enzyme activity

Optical determination of glucose utilizing boronic acid adducts

Method and apparatus for detecting an analyte

Environmentally stable sensors and methods of using the same

MULTICOLOR BIOLUMINESCENT VISUALIZATION PROBE SET, OR SINGLE-MOLECULE-FORMAT MULTICOLOR BIOLUMINESCENT VISUALIZATION PROBE

Method for simultaneous analysis of multiple biological reactions or changes in in vivo conditions

Surface Receptor Complexes as Biomarkers

Bivalent thrombin binding molecules comprising linkers

Visual glucose sensor and methods of use thereof

METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS USING TWO-PHOTON SIMULTANEOUS ABSORPTION

Motif of the beclin protein which interacts with anti-apoptotic members of the Bcl-2 protein family, and uses

PHOTOSTABLE FRET-COMPETENT BIARSENICAL-TETRACYSTEINE PROBES BASED ON FLUORINATED FLUORESCEINS

COLLOIDAL METAL AGGREGATES AND METHODS OF USE

RET-Based Analyte Detection

Compositions and Methods For Signal Generation

Homogeneous luminescence bioassay

Saccharidic fluorescent substrates, their process of preparation and their use

USING PHOTO-RESPONSIVE SURFACTANTS TO REVERSIBLY CONTROL PROTEIN AGGREGATION WITH LIGHT ILLUMINATION

Split protein fragments, split protein systems, methods of making split protein systems, and methods of using split protein systems

Bisdeoxycoelenterazine derivatives, methods of use, and BRET2 systems

Compounds and methods of use thereof for assaying lysophospholipase D activity

METHOD FOR EVALUATING DRUG CANDIDATES

Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications

Screening assay to identify modulators of protein kinase A

Binary signaling assay using a split-polymerase

Modulators of Retinol-Retinol Binding Protein (RBP)-Transthyretin (TTR) Complex Formation

Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye

Estrogen receptor intramolecular folding systems, estrogen receptor intramolecular folding sensors, methods of use thereof, methods of detecting ER ligands, and methods of detecting ER agonists and antagonists

Aromatic triamide-lanthanide complexes

Novel Use of Fluorescence Resonance Energy Transfer

Enzyme sensors including environmentally sensitive or fluorescent labels and uses thereof

Genetically encoded bioindicators of calcium-ions

Immunoassay method and reagent therefor

Method for quantitative analysis of interactions between HIF-1alpha C-terminal peptides and CBP or p300 proteins and method of screening inhibitors using the same

Novel Applications of Acridinium Compounds and Derivatives in Homogeneous Assays

METHOD FOR MEASURING A TARGET SUBSTANCE AND A KIT FOR MEASURING A TARGET SUBSTANCE

METHOD FOR DETERMINATION OF CONCENTRATION, CHARGE OR UNIT SIZE OF A SUBSTANCE

Biosensors, method for obtaining the same and uses thereof

Use of Sequence Specific Polymers in Chemical Detection

Detecting and Profiling Molecular Complexes

Organic Compounds

Masking background fluorescence and luminescence in the optical analysis of biomedical assays

Deeply quenched enzyme sensors

Photoinduced Signal Amplification Through Externally Sensitized Photofragmentation in Masked Photosensitizers

Differential Immunoassay

Multimetric Biosensors and Methods of Using Same

Applications of acridinium compounds and derivatives in homogeneous assays

Fluorescence polarization assays for determining clostridial toxin activity

Fluorescence polarization assays for determining clostridial toxin activity

Probe for nucleic acid sequencing and methods of use

Saccharide fluorescent substrates, preparation method and uses thereof

Fluorescent methods and materials for directed biomarker signal amplification

Fluorescence polarization assays for determining clostridial toxin activity

Fluorescence polarization assays for determining clostridial toxin activity

Methods and Reagents for Elimination or Reduction of False Positives in the Analysis of a Sample

Means and methods for the determination of camp in vitro and in vivo

Non-invasive real-time in vivo bioluminescence imaging of local Ca+ dynamics in living organisms

Hybrid nucleic acid assembly

Method for detecting a hydrophobic region of a target substance

Antibody-based arrays for detecting multiple signal transducers in rate circulating cells

Cell Free Assay for Determining a Substance of Interest and Molecular Complexes Used Therefore

Proteins, sensors, and methods of characterizing analytes using the same

Detecting molecular interactions by fluorescence resonance energy transfer on a solid-phase support

ASSAY METHOD FOR GROUP TRANSFER REACTIONS

Detecting and profiling molecular complexes

Assay method for group transfer reactions

HOMOGENEOUS ASSAY FOR ENZYMATIC ACTIVITY

Method for the detection of target molecules by fluorescence polarization using peptide mimics

Fluorescence polarization-based homogenous assay for aflatoxins

Resonance Energy Transfer System and Method

Fluorescent protein and chromoprotein

Luminescence resonance energy transfer (LRET) assays for clostridial toxin activity

SENSOR PROTEINS AND ASSAY METHODS

FLUORESCENT POLYMER SUPERQUENCHING-BASED BIOASSAYS

Screening using polarization anisotropy in FRET emissions

Assay and kit for drug efflux transporter activity

Compositions for the detection of enzyme activity in biological samples and methods of use thereof

Fiber optic device for sensing analytes

ERBB HETERODIMERS AS BIOMARKERS

Detection of analytes using reorganization energy

Fluorescent Indicators of Hydrogen Peroxide and Methods for Using Same

Correction method and measurement device for anti-stokes photoluminescence measurement

Detection of analytes using reorganization energy

Detection of analytes using reorganization energy

Detection of conformationally altered proteins and prions

Detection of analytes using reorganization energy

Molecular biosensors for use in competition assays

Immunochromatography kit

Biosensor

Fusion Proteins and Methods for Determining Protein-Protein-Interactions in Living Cells and Cell Lysates, Nucleic Acids Encoding these Fusion Proteins, as well as Vectors and Kits Containing These

Enhancement of sensitivity of fluorophore mediated biosensing and bioimaging

Lipophilic dye-based fret assays for clostridal toxin activity

Method of detection of cAMP and cGMP via a fluorophore and dequencher complex

OPTICAL PROBES AND ASSAYS

Protein fragment complementation assays in whole animals applications to drug efficacy, adme, cancer biology, immunology, infectious disease and gene therapy

Detection of analytes using reorganization energy

Antibody that binds uridine diphosphate

Homogeneous analyte detection

Sequential analysis of biological samples

Sequential analysis of biological samples

Sequential analysis of biological samples

Method for detecting oligermization of soluble amyloid beta oligomers

Kits and peptides for transferases

SENSITIZER-LABELED ANALYTE DETECTION

Resonance Energy Transfer Assay System for Multi-Component Detection

Nucleic acid molecules encoding emission ratiometric indicators of phosphoinositides

Method of controlling quantum dot photoluminescence and other intrinsic properties through biological specificity

Methods and devices for diagnostic testing

Method for Spatially High-Resolution Investigation of a Structure, Marked With a Fluorescing Substance, of a Specimen

FRET-based apoptosis detector

High throughput screening assay for histone modifying enzyme modulators

ASSAYS FOR IDENTIFYING UBIQUITIN AGENTS AND FOR IDENTIFYING AGENTS THAT MODIFY THE ACTIVITY OF UBIQUITIN AGENTS

FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET) ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY

Cooperative reporter systems, components, and methods for analyte detection

METHODS FOR CARBOXYPEPTIDASES

BIOLUMINESCENCE RESONANCE ENERGY TRANSFER REPORT ELEMENT FOR BIOLOGICAL ARRAYS

Identification of substances that inhibit NEMO oligomerization

Three-component biosensors for detecting macromolecules and other analytes

Rapid and sensitive assay for the detection and quantification of coregulators of nucleic acid binding factors

Method for Detection of Conformational Change of a Protein Immobilized on a Substrate

Assay for ubiquitin mediated proteolysis

Method for measuring dissociation constant by surface plasmon resonance analysis

Ligand-regulable transactivation systems, methods of use thereof, methods of detecting estrogen receptor ligands, and methods of differentiating estrogen receptor ligand agonists and antagonists

COMPOSITIONS AND METHODS FOR MEASURING ANALYTE CONCENTRATIONS

Assays for identification of topoisomerase inhibitors

Neurotransmitter sensors and methods of using the same

High quantum yield acridinium compounds and their uses in improving assay sensitivity

Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents

NMR-SOLVE METHOD FOR RAPID IDENTIFICATION OF BI-LIGAND DRUG CANDIDATES

Probe Complex

Determining enantiomeric excess using indicator-displacement assays

Modular molecular clasps and uses thereof

Assays of molecular or subcellular interactivity using depolarization after resonance transfer energy (DARET)

Detection of molecular interactions

KINASE AND UBIQUINATION ASSAYS

Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection