169324 ⎘
Investigating or analysing materials by specific methods not covered by groups -; Biological material, e.g. blood, urine ; Haemocytometers; Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids Intracellular protein regulatory factors and their receptors, e.g. including ion channels
High-Throughput Cell-Based Screening Methodology For Evaluating Carbohydrate-Active Enzymes
#302Activatable antibodies that bind epidermal growth factor receptor and methods thereof
#303Graphene oxide-based nanolab and methods of detecting of exosomes
#304DOC2B AS A BIOMARKER FOR TYPE 1 DIABETES
#305Modifiers of CFTR-directed therapy
#306Systems and methods for determining a chemical state
#307NEUROPILIN-1 SPECIFIC BINDING PEPTIDE, FUSION PROTEIN FUSED WITH SAME, AND USE THEREOF
#308Loss of function mutations in cause SeSAME, a human syndrome with sensory, neurological, and renal deficits
#309Biomarkers, test method, and test kit for predicting therapeutic effect of anti-VEGFR-2 antibody drug
#310Target Detection with Nanopore
#311Use of leucine-zipper protein for diagnosis or treatment of fatty liver
#312Compositions and methods for modulating dysferlin expression
#313INDUCTION OF SENESCENCE USING PROTON PUMP INHIBITORS
#314NOVEL TFEB PATHWAY AGONISTS FOR METABOLIC DISEASES AND AGEING
#315COMPOSITIONS AND METHODS FOR FETAL GROWTH
#316Molecularly imprinted polymer sensors for neurotrophic factors
#317METHOD OF IDENTIFYING ADIPOSE STEM CELLS
#318Screening method for materials that suppress characteristic body odor of elderly people
#319Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use
#320KITS FOR DETECTION OF HEPCIDIN
#321Biosensors and methods for detection of lysophosphatidic acid for signaling of ovarian cancer
#322Identification and monitoring of apoptosis inhibitor of macrophage
#323CONJUGATED PROTEINS AND USES THEREOF
#324Use of radiolabeled nanobody in prognosis and diagnosis of cancer
#325Methods of identifying a moldulator of otopetrin-mediated proton translocation activity
#326Cystic fibrosis transmembrane conductance regulator gene mutations
#327Glypican-3-binding fibronectin based scaffold molecules
#328Membrane and droplet-interface bilayer systems and methods
#329CONJUGATES FOR TREATING INFLAMMATORY DISEASE AND IDENTIFICATION OF PATIENTS LIKELY TO BENEFIT FROM SUCH TREATMENT
#330Selection of agents modulating gastrointestinal pain
#331METHODS TO TARGET PKD1/PKD2 ION CHANNEL COMPLEX
#332MODULATORS OF ALPHA-SYNUCLEIN
#333INHIBITOR OF TRPM-4 ION CHANNEL FOR TREATING OR PREVENTING NEURODEGENERATION
#334IDENTIFICATION OF PATIENTS IN NEED OF PD-L1 INHIBITOR COTHERAPY
#335Serotonin transporter gene and treatment of opioid-related disorders
#336Humanized or chimeric CD3 antibodies
#337METHODS FOR TREATING DRUG RESISTANT CANCERS
#338Methods for detecting Na/K-ATPase-mediated Src signaling for diagnosis and prognosis of cancer
#339DIAGNOSTIC METHODS FOR NEURAL DISORDERS
#340KV1.3-BLOCKING VENOM PEPTIDE VARIANTS AND RELATED USES
#341Predicting patient response to sodium channel blockers
#342Recombinant cardiomyocytes and cardiomyocyte cell lines expressing hERG
#343MYB-RELATED TRANSCRIPTION FACTOR (MYPOP) AS DIAGNOSTIC MARKER AND THERAPEUTIC TARGET FOR TUMOR THERAPY
#344IL-10, S100B AND H-FABP MARKERS AND THEIR USE IN DETECTING TRAUMATIC BRAIN INJURY
#345Cardiovascular Risk Event Prediction and Uses Thereof
#346Epitopes in the RNA recognition motif 1 (RRM1) of TDP-43 and misfolding-selective antibodies thereto
#347ANTIGEN BINDING CONSTRUCTS TO CD8
#348Substituted heterocyclic compounds as allosteric modulators of group II metabotropic glutamate receptors
#349Bone Marrow Adipose Portion Isolation Device and Methods
#350HUMANIZED OR CHIMERIC CD3 ANTIBODIES
#351Nucleic acid molecules encoding anti-GPRC5D antibodies
#352METHODS OF TREATING CANCERS USING ANTI-GPRC5D ANTIBODIES
#353Compositions and methods for programmable sensing and control through combinatorial molecular interactions
#354Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
#355Modulators of ATP-binding cassette transporters
#356Cell analysis system, cell analysis program and cell analysis method
#357CHIMERIC RECEPTOR FOR USE IN WHOLE-CELL SENSORS FOR DETECTING ANALYTES OF INTEREST
#358Method for inhibiting calcification of a smooth muscle cell (SMC)
#359Agents that modulate immune cell activation and methods of use thereof
#360Affinity-oligonucleotide conjugates and uses thereof
#361EGFR-binding agents and uses thereof
#362Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
#363Soluble mediator
#364CELL LINE, SYSTEM AND METHOD FOR OPTICAL-BASED SCREENING OF ION-CHANNEL MODULATORS
#365ANTIBODIES TO NON-FUNCTIONAL P2X7 RECEPTOR
#366PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST CANCERS
#367Soluble CD33 for treating myelodysplastic syndromes (MDS)
#368Methods for in vitro investigating mitochondrial replication dysfunction in a biological sample, kits and uses thereof, therapeutic methods against progeroid-like syndromes or symptoms and screening method for identifying particular protease inhibitor(s) and/or nitroso-redox stress scavenger compound(s)
#369Endoglin Antibodies
#370NOVEL USE OF REGULATORY T CELL-SPECIFIC SURFACE PROTEIN LRIG-1
#371Use of caspase-3 inhibitors and caspase-3 activators in the manufacture of medicament for treating cancer and wound healing
#372ANTIBODY AND ANTIGEN RECOGNIZING TUMOR-INITIATING CELLS AND USE THEREOF
#373Modified integrin polypeptides, modified integrin polypeptide dimers, and uses thereof
#374Protein binding domains stabilizing functional conformational states of GPCRS and uses thereof
#375FOXC1 ANTIBODIES AND METHODS OF THEIR USE
#376TRPC6 involved in glomerulonephritis
#377BAFF selective binding compounds and related methods
#378Methods and compositions for SIRT1 expression as a marker for endometriosis and subfertility
#379Method for assessing the efficacy of IMiDs and composition or combination for use in treating IMiD sensitive diseases
#380NEUROPILIN-1 SPECIFIC BINDING PEPTIDE, FUSION PROTEIN FUSED WITH SAME, AND USE THEREOF
#381Synthetic library of specific binding molecules
#382METHODS AND COMPOSITIONS FOR MODIFYING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR ACTIVITY
#383System for optical stimulation of target cells
#384PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#385Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof
#386PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#387PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#388PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#389Methods and compositions useful in detecting proteins
#390METHOD TO PREDICT THE PATTERN OF LOCOMOTION IN HORSES
#391ANTIGEN BINDING CONSTRUCTS TO CD8
#392ANTIGEN BINDING CONSTRUCTS TO CD8
#393Anastasis biosensor
#394DIAGNOSTIC AND SCREENING METHODS FOR ATOPIC DERMATITIS
#395Mutations associated with cystic fibrosis
#396Use of recombinant lymphocyte activation gene-3 as a companion therapeutic for patients at risk for cardiovascular disease and other chronic inflammatory diseases
#397Sensors and assays for ubiquitin or ubiquitin-like proteins
#398Lipocalin muteins with binding affinity for LAG-3
#399PD-L1 binding polypeptides for imaging
#400RNA-YY1 Interactions
#401Material for screening for compound acting on ION channel and use thereof
#402CRY1-Clock-BMAL1 Complex-Disrupting Agents and Methods of Identifying and Using Same
#403LYMPHANGIOGENESIS-PROMOTING AGENTS
#404Anti-complement factor H antibodies
#405TRPA1 and TRPV4 inhibitors and methods of using the same for organ-specific inflammation and itch
#406Rhodol-based thallium sensors for high-throughput screening of potassium channels
#407Non-alcoholic fatty liver regulator 14-3-3 protein
#408NOVEL ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE
#409Use of leucine-zipper protein for diagnosis or treatment of fatty liver
#410METHOD OF PREDICTING RESPONSIVENESS OF WET AMD PATIENT TO ANTI-VEGF THERAPY
#411METHODS FOR IDENTIFYING MODULATORS OF MEMBRANE POTENTIALS IN BIPOLAR DISORDER AND ATTENTION DEFICIT HYPERACTIVITY DISORDER
#412SRM/MRM Assays For CD56 And CHGA Proteins
#413Systems and methods to identify and treat subjects at risk for obstetrical complications
#414Disruption of EGFR-SAR1 interaction for cancer treatment
#415USE OF sCD14 OR ITS FRAGMENTS OR DERIVATIVES FOR RISK STRATIFICATION, DIAGNOSIS AND PROGNOSIS
#416Drug target for preventing pathologic calcium overload in cardiomyocytes and methods of screening for same
#417Serotonin transporter gene and treatment of opioid-related disorders
#418NOVEL IGFR-LIKE RECEPTOR AND USES THEREOF
#419Modified cystic fibrosis transmembrane conductance regulator (CFTR) polypeptides with increased stability and uses thereof
#420COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX
#421Electrophysiological assays using oocytes that express human enac and the use of phenamil to improve the effect of enac enhancers in assays using membrane potential reporting dyes
#422Methods for determining drug effects on a mature cardiomyocyte
#423System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators
#424Methods of identifying modulators of SAMTOR-GATOR1 interaction and use of same to modulate mTORC1
#425Method of synthesizing antagonist peptides for cell growth
#426Method for identifying modulators of notch signaling
#427Methods for screening cereblon modifying compounds
#428CAMEL DERIVED POLYPEPTIDES BINDING HUMAN CD3, IDENTIFIED USING A NOVEL ONE-STEP METHOD
#429Mutant light-inducible ion channel of chrimson
#430Compounds and methods for the detection of TRPV-6 cancers and drug delivery
#431Soluble mediator
#432COMPOSITION AND METHODS FOR MEASURING ION CHANNEL ACTIVITY IN A CELL
#433Use of regulatory T cell-specific surface protein LRIG-1
#434Cell-permeable imaging sensors and uses thereof
#435METHODS AND COMPOSITIONS FOR APPETITE CONTROL AND WEIGHT MANAGEMENT
#436Marker for statin treatment stratification in heart failure
#437ASSAYS AND ENHANCERS OF THE HUMAN DELTA ENAC SODIUM CHANNEL
#438Mitochondria-targeting fluorescent potassium+ sensor and method of making the same
#439Nucleic acids encoding antibodies with high affinity for Alpha-Klotho
#440Modulators of ATP-binding cassette transporters
#441Methods involving Menain screening for inhibitors of cancer invasion and metastasis
#442Humanized affinity matured anti-FcRn antibodies
#443METHOD FOR INFERRING ACTIVITY OF A TRANSCRIPTION FACTOR OF A SIGNAL TRANSDUCTION PATHWAY IN A SUBJECT
#444Defective calcium signaling as a tool in autism spectrum disorders
#445Single-molecule pore-based sensor for proteins and transient protein-protein interactions
#446Targeting NCchannel for organ protection following ischemic episode
#447HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODIES TO CD47
#448TGF-receptor II isoform, fusion peptide, methods of treatment and methods in vitro
#449ACTIVATION OF TRPV4 ION CHANNEL BY PHYSICAL STIMULI AND CRITICAL ROLE FOR TRPV4 IN ORGAN-SPECIFIC INFLAMMATION AND ITCH
#450METHODS FOR IDENTIFYING AND TREATING HEMOGLOBINOPATHIES
#451Calcium sensing receptors, ligands, compositions, and methods of use
#452System for optical stimulation of target cells
#453Determination of JAK-STAT3 pathway activity using unique combination of target genes
#454Ytterbium as a surrogate cation to measure calcium flux
#455METHOD OF IDENTIFYING ADIPOSE STEM CELLS
#456Polypeptides and uses thereof for reducing CD95-mediated cell motility
#457PROTEIN VARIANTS FOR USE AS LIPID BILAYER-INTEGRATED NANOPORE, AND METHODS THEREOF
#458Cell analysis system, cell analysis program and cell analysis method
#459DEVICES, COMPOSITIONS AND RELATED METHODS FOR DIAGNOSING AUTISM
#460Step-function channelrhodopsins for optical control of cells
#461Glypican-3-binding fibronectin based scaffold molecules
#462Mannitol-based amphipathic compound and use thereof
#463Methods for measuring analyte transport across barriers using X-ray fluorescence
#464MSP nanopores and related methods
#465NOVEL BT TOXIN RECEPTORS AND METHODS OF USE
#466Binding members to PD-L1
#467METHODS AND COMPOSITIONS FOR MODULATING HGF/MET
#468Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof
#469LIGHT-ACTIVATED CATION CHANNEL AND USES THEREOF
#470Peptide-based methods for treating neurological injury
#471PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#472MEASURING CIRCULATING THERAPEUTIC ANTIBODY, ANTIGEN AND ANTIGEN/ANTIBODY COMPLEXES USING ELISA ASSAYS
#473Methods for decreasing chord length
#474Methods of identifying modulators of CASTOR1-GATOR2 interaction and use of same to modulate mTORC1
#475Single cell characterization using affinity-oligonucleotide conjugates and vessel barcoded polynucleotides
#476Diagnostic methods for neural disorders
#477Collapsible element pocket former
#478Sensitivity markers and uses for CDK7 inhibitors in breast cancers
#479Collapsible element pocket former
#480Yeast cells expressing TAR DNA-binding protein 43 and uses therefor
#481Fusion proteins comprising partial tetraspanin sequences and a system thereof for presenting peptides on the cell surface
#482Peptides and combination of peptides for use in immunotherapy against cancers
#483DEVICE FOR DETECTING NEUROTOXINS AND PROCESS FOR MANUFACTURE THEREOF
#484Serotonin transporter gene and treatment of alcoholism
#485TDP-43 in degenerative disease
#486Use of glu-tubulin as a biomarker of drug response to furazanobenzimidazoles
#487Sensors and assays for ubiquitin or ubiquitin-like proteins
#488Treatment of tinnitus through modulation of chloride co-transporter NKCC1 in the auditory system
#489Method for analyzing the activity of an ion channel
#490Binding-triggered transcriptional switches and methods of use thereof
#491CD318 as a marker for, and CD318 inhibition as a treatment for, autoimmune disease
#492Methods for diagnosing and treating inflammatory bowel disease
#493Monomeric and Dimeric Forms of Adiponectin Receptor Fragments and Methods of Use
#494Use of receptor-binding domain derived from bovine leukemia virus for the diagnosis or treatment of cationic l-amino acid transporter-related diseases
#495Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
#496Light-activated cation channel and uses thereof
#497Anti-hypusine antibodies and uses thereof
#498PEPTIDES
#499Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis
#500Soluble MANF in pancreatic beta-cell disorders
#501Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
#502Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use
#503Methods and compositions relating to proteasome inhibitor resistance
#504Bone marrow adipose portion isolation device and methods
#505Biosensors for cellular osmolarity
#506Method for detecting lipid bilayer membrane particles or fragments thereof
#507Systems and methods for determining a chemical state
#508Micro- and nano-device for cartilage injury detection and treatment
#509KITS FOR STRATIFYING SCOLIOTIC SUBJECTS
#510DIAGNOSTIC ASSAYS FOR SUPAR-β3 INTEGRIN DRIVEN KIDNEY DISEASES
#511Antibodies that bind human cannabinoid 1 (CB1) receptor
#512FALZ for use as a target for therapies to treat cancer
#513IDENTIFICATION OF PATIENTS IN NEED OF PD-L-1 INHIBITOR COTHERAPY
#514Glycated CD59 peptides, their preparation, and uses thereof
#515Methods of treating cancer with a P2X7 peptide
#516Selection of agents modulating gastrointestinal pain
#517Soluble mediator
#518METHODS AND COMPOSITIONS FOR DETERMINING THE POTENCY OF A THERAPEUTIC CELLULAR COMPOSITION
#519Microparticle fractionation
#520MODIFIERS OF CFTR-DIRECTED THERAPY
#521Targeted delivery system and methods of use therefor
#522Methods of diagnosing and treating hyperproliferative disorders
#523KITS, COMPOSITIONS AND METHODS FOR DETECTING A BIOLOGICAL CONDITION
#524Method of treating pain with an antibody against netrin-4, UNC5B or neogenin
#525SecA INHIBITORS AND METHODS OF MAKING AND USING THEREOF
#526Methods for Identifying Compounds that Directly Bind to Insect Transient Receptor Potential Channels
#527COMPOSITIONS AND METHODS FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS
#528Compositions and methods for modulating ABHD2 activity
#529Non-alcoholic fatty liver regulator 14-3-3 protein
#530Methods and compositions for diagnosis and prognosis of renal injury and renal failure
#531METHODS FOR USING EXOSOMES TO MONITOR TRANSPLANTED ORGAN STATUS
#532Nanopores with internal protein adaptors
#533Binding-triggered transcriptional switches and methods of use thereof
#534Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use
#535Membrane and droplet-interface bilayer systems and methods
#536Cystic fibrosis transmembrane conductance regulator gene mutations
#537Endoglin Antibodies
#538Activators of TonEBP for use for hydrating skin
#539COMPOSITIONS AND METHODS FOR MODULATING PRO-INFLAMMATORY IMMUNE RESPONSE
#540Compositions and methods for programmable sensing and control through combinatorial molecular interactions
#541METHODS FOR TREATING NEURAL CELL SWELLING
#542SYSTEMS AND METHODS FOR PREDICTING CARDIOTOXICITY OF MOLECULAR PARAMETERS OF A COMPOUND BASED ON MACHINE LEARNING ALGORITHMS
#543Methods of determining interferon having direct inhibitory effects on tumors and uses thereof
#544Sortilin 1 is a novel inducer of vascular calcification
#545Modulators of ATP-binding cassette transporters
#546Method for monitoring cancer and/or inflammatory reaction based on RelB phosphorylation
#547Treatment and Diagnosis of Hereditary Xerocytosis
#548SYNAPTIC VESICLE CYCLING ASSAYS AND SYSTEMS
#549Methods for Monitoring Responsiveness to Anti-SMAD7 Therapy
#550Antibodies targeting G-protein coupled receptor and methods of use
#551Multiples multiplex immunohistochemical assay using primary antibodies of the same host species
#552Method for determining the survival prognosis of a patient suffering from pancreatic cancer
#553METHODS AND COMPOSITIONS FOR USING MHC CLASS II INVARIANT CHAIN POLYPEPTIDES AS A RECEPTOR FOR MACROPHAGE MIGRATION INHIBITORY FACTOR
#554Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof
#555Graphene oxide-based nanolab and methods of detecting of exosomes
#556Diagnostic and screening methods for atopic dermatitis
#557Modulating the aryl hydrocarbon receptor system to treat major depressive disorder
#558Hydrogel network
#559Method of using transmembrane channel-like protein 6 (TMC6) protein to identify substances affecting salty taste
#560NOVEL MONOCLONAL ANTIBODY INHIBITORS TARGETING POTASSIUM CHANNEL KCNK9
#561T1R taste receptors and genes encoding same
#562SAB as a biomarker for degenerative diseases and therapeutic sensitivity in cancers
#563Cell line stably expressing Nav1.5 and method of screening therapeutic agent using the cell line
#564Method of identifying human compatible T cell receptors specific for an antigenic target
#565Binding-triggered transcriptional switches and methods of use thereof
#566SYSTEMS AND METHODS OF SELECTING COMPOUNDS WITH REDUCED RISK OF CARDIOTOXICITY USING CARDIAC SODIUM ION CHANNEL MODELS
#567Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof
#568Methods for the diagnosis and treatment of Sjögren's syndrome
#569COMBINATION THERAPY OF CANCER WITH ANTI-ENDOGLIN ANTIBODIES AND ANTI-VEGF AGENTS
#570Method for achieving desired glial growth factor 2 plasma levels
#571Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies
#572Neuropilin-1 specific binding peptide, fusion protein fused with same, and use thereof
#573Inflammasome activation in myelodysplastic syndromes
#574Methods And Compositions For Modifying Sensorial Perception
#575Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays
#576Detection method and kit
#577Mutant smoothened and methods of using the same
#578Compositions and methods for expressing polypeptides on the surface of cells
#579Optogenetic probes for measuring membrane potential
#580Method for diagnosing a molecular phenotype of a patient suffering from an illness accompanied by chronic inflammation
#581Anti-PD-1 antibodies
#582NOVEL VOLTAGE-DEPENDENT ION CHANNEL FUSIONS AND METHOD OF USE THEREOF
#583ACTIVATION OF TRPV4 ION CHANNEL BY PHYSICAL STIMULI AND CRITICAL ROLE FOR TRPV4 IN ORGAN-SPECIFIC INFLAMMATION AND ITCH
#584Method for the early diagnosis of a pre-diabetic state and type 2 diabetes
#585NOVEL BT TOXIN RECEPTORS AND METHODS OF USE
#586Surface plasmon resonance approach to monitor protein-ligand interactions
#587Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
#588CD247 as a biomarker for assessing the effect of chemotherapeutic and biological drugs
#589Systems and Methods for Detecting a Biological Condition
#590Simultaneous detection of cannibalism and senescence as prognostic marker for cancer
#591CEREBLON ISOFORMS AND THEIR USE AS BIOMARKERS FOR THERAPEUTIC TREATMENT
#592Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays
#593Method to predict the pattern of locomotion in horses
#594Methods of selecting compstatin mimetics
#595System for optical stimulation of target cells
#596BK Channels as Non-Genomic Estrogen Targets for Overactive Bladder
#597Methods of reducing viscosity of biological samples
#598Bak binding proteins
#599Reduction in CPC taste aversion by reducing CPC activation of TRPA1, TPRV1, or both
#600Polypeptide immunogen for generating an antibody to non-functional P2X7 receptor