Inventor profile of:

James Bradner

City:

Weston, Massachusetts

Country:

United States

Published Applications:

39

Last publication date:

2024-10-17

Top Assignees for applications by James Bradner

The entities that hold a legal rights for patent applications filed by inventor Bradner James:

Recent patent applications by Bradner James

James Bradner from Weston, US has applied for patents for these inventions. The list has both pending applications and granted patents:

#1 | 2024-10-17
US20240342173A1
Human necessities

CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE TREATMENT OF RIBOSOMAL DISORDERS AND RIBOSOMAPATHIES

#2 | 2024-09-19
US20240309084A1
Chemistry; metallurgy

DEGRADATION OF EXTRACELLULAR TARGETS

#3 | 2024-03-21
US20240092735A1
Chemistry; metallurgy

COMPOUNDS AND METHODS FOR TREATING CANCER

#4 | 2023-09-07
US20230279394A1
Chemistry; metallurgy

COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES

#5 | 2023-04-27
US20230131952A1
Chemistry; metallurgy

DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE

#6 | 2022-05-05
US20220135967A1
Chemistry; metallurgy

TUNABLE ENDOGENOUS PROTEIN DEGRADATION

#7 | 2022-01-13
US20220008420A1
Human necessities

Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies

#8 | 2021-09-30
US20210301286A1
Chemistry; metallurgy

TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY ASSOCIATED ADVERSE INFLAMMATORY RESPONSES

#9 | 2021-05-20
US20210147359A1
Chemistry; metallurgy

Compounds and methods for treating cancer

#10 | 2021-03-04
US20210061811A1
Chemistry; metallurgy

Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use

#11 | 2021-01-21
US20210015929A1
Human necessities

Methods to induce targeted protein degradation through bifunctional molecules

#12 | 2020-10-08
US20200317635A1
Chemistry; metallurgy

Methods to induce targeted protein degradation through bifunctional molecules

#13 | 2020-07-09
US20200216454A1
Chemistry; metallurgy

BIFUNCTIONAL MOLECULES FOR HER3 DEGRADATION AND METHODS OF USE

#14 | 2020-01-23
US20200024267A1
Chemistry; metallurgy

Chromobox protein inhibitors and uses thereof

#15 | 2020-01-09
US20200010418A1
Chemistry; metallurgy

Compounds and methods for treating cancer

#16 | 2019-12-12
US20190374657A1
Human necessities

Tunable endogenous protein degradation with heterobifunctional compounds

#17 | 2019-12-12
US20190374528A1
Human necessities

Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use

#18 | 2019-12-05
US20190365875A1
Human necessities

Regulating chimeric antigen receptors

#19 | 2019-10-17
US20190314374A1
Human necessities

Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies

#20 | 2019-08-29
US20190263823A1
Chemistry; metallurgy

Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use

#21 | 2019-08-15
US20190247509A1
Human necessities

Degradation of bromodomain-containing protein 9 (BRD9) by conjugation of BRD9 inhibitors with E3 ligase ligand and methods of use

#22 | 2019-07-11
US20190209535A1
Human necessities

Degradation of tripartite motif-containing protein 24 (TRIM24) by conjugation of TRIM24 inhibitors with E3 ligase ligand and methods of use

#23 | 2019-05-23
US20190151457A1
Human necessities

Methods to induce targeted protein degradation through bifunctional molecules

#24 | 2019-05-09
US20190134141A1
Human necessities

METHODS OF DOWNREGULATING TRANSLOCATED ONCOGENE EXPRESSION USING BROMODOMAIN INHIBITORS

#25 | 2019-03-07
US20190071415A1
Chemistry; metallurgy

Methods to induce targeted protein degradation through bifunctional molecules

#26 | 2019-01-17
US20190016703A1
Chemistry; metallurgy

BIFUNCTIONAL COMPOUNDS FOR HER3 DEGRADATION AND METHODS OF USE

#27 | 2018-11-15
US20180327419A1
Chemistry; metallurgy

Targeted protein degradation using a mutant E3 ubiquitin ligase

#28 | 2018-06-28
US20180179522A1
Chemistry; metallurgy

Tunable endogenous protein degradation

#29 | 2018-06-21
US20180169109A1
Human necessities

Targeted protein degradation to attenuate adoptive T-cell therapy associated adverse inflammatory responses

#30 | 2018-05-31
US20180148410A1
Chemistry; metallurgy

Compounds and methods for treating cancer

#31 | 2018-05-17
US20180134684A1
Chemistry; metallurgy

Methods to induce targeted protein degradation through bifunctional molecules

#32 | 2018-03-29
US20180085465A1
Human necessities

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES

#33 | 2018-01-11
US20180009779A1
Chemistry; metallurgy

Methods to induce targeted protein degradation through bifunctional molecules

#34 | 2017-12-21
US20170360801A1
Human necessities

Bromodomain inhibitor as adjuvant in cancer immunotherapy

#35 | 2016-08-25
US20160243247A1
Human necessities

Methods to induce targeted protein degradation through bifunctional molecules

#36 | 2016-08-18
US20160235731A1
Human necessities

Methods to induce targeted protein degradation through bifunctional molecules

#37 | 2016-08-18
US20160235730A1
Human necessities

Methods to induce targeted protein degradation through bifunctional molecules

#38 | 2016-06-23
US20160176916A1
Chemistry; metallurgy

Methods to induce targeted protein degradation through bifunctional molecules

#39 | 2014-12-18
US20140371157A1
Human necessities

Method for identifying bromodomain inhibitors

InventorID:

1007420 ⎘