Jon A Wolff

Reversibly masked polymers

In vivo polynucleotide delivery conjugates having enzyme sensitive linkages

Polyconjugates for in vivo delivery of polynucleotides

In vivo polynucleotide delivery conjugates having enzyme sensitive linkages

Peptide-based in vivo siRNA delivery system

Method for single-step attachment of a label to target molecules

Intravenous delivery of polynucleotides to cells in mammalian limb

Process for delivering sirna to cardiac muscle tissue

Delivery of molecules and complexes to mammalian cells in vivo

Intravascular delivery of nucleic acid

Membrane active heteropolymers

Membrane active heteropolymers

Endosomolytic poly(acrylate) polymers

Endosomolytic poly(vinyl ether) polymers

Endosomolytic Modified Poly(Alcohol) and Poly(Amine) Polymers

Reversibly Masked Polymers

Endosomolytic Poly-Beta-Aminoester Polymers

Process for utilizing epitopes recognized by natural antibodies

Charge Reversal of Polyion Complexes

Intravascular delivery of nucleic acid

Charge reversal of polyion complexes

Polyconjugates for in vivo delivery of polynucleotides

Devices and processes for distribution of genetic material to mammalian limb

Chelating Compound for Drug Delivery

Enhancing intermolecular integration of nucleic acids using integrator complexes

Compound containing a labile disulfide bond

Lipid-mediated polynucleotide administration to deliver a biologically active peptide and to induce a cellular immune response

Expression of zeta negative and zeta positive nucleic acids using a dystrophin gene

Inhibition of gene expression by delivery of polynucleotides to animal cells in vivo

Nucleic acid injected into hepatic vein lumen

Devices and processes for distribution of genetic material to mammalian limb

Compositions and methods for drug delivery using pH sensitive molecules

Polyampholytes for delivering polyions to a cell

Endosomolytic polymers

Methods for genetic immunization

Micellar systems

Intravascular delivery of non-viral nucleic acid

Compositions and methods for drug delivery using pH sensitive molecules

Compositions and processes using siRNA, amphipathic compounds and polycations

Nucleic acid injected into hapatic vein lumen and delivered to primate liver

Compounds and processes for single-pot attachment of a label to nucleic acid

Micellar systems

Compounds and processes for single-pot attachment of a label to siRNA

Process of making a compound by forming a polymer from a template drug

Compounds for targeting hepatocytes

Compounds for targeting hepatocytes in vivo

Reversible modification of amine-containing compounds

Process of making a compound by forming a polymer from a template drug

Gene expression with covalently modified polynucleotides

Process for generating multilayered particles

Intravascular delivery of nucleic acid

pH-titratable polyampholytes for delivering polyions to a cell

Process of making a compound by forming a polymer from a template drug

In vivo inhibition of hepatitis B virus

Formation of polyampholytes in the presence of a polyion

Process of making a compound by forming a polymer from a template drug

Gene expression with covalently modified polynucleotides

Polymerized formamides for use in delivery of compounds to cells

Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo

Reversible modification of membrane interaction

Process of making a compound by forming a polymer from a template drug

Process for delivering nucleic acids to cardiac tissue

DNA cassette for cellular expression of small RNA

Therapeutic fusion protein transgenes

Compound containing a labile disulfide bond

Intravascular delivery of nucleic acid

Formation of polyampholytes in the presence of a polyion

Compositions and methods for drug delivery using pH sensitive molecules

Intravascular delivery of non-viral nucleic acid

Compositions and processes using siRNA, amphipathic compounds and polycations

Process of delivering a virally encapsulated polynucleotide or viral vector to a parenchymal cell via the vascular system

Compositions and methods for drug delivery using pH sensitive molecules

Polynucleotide complex delivery

Formation of polyampholytes in the presence of a polyion

In vitro process for selecting phage resistant to blood inactivation

Process for delivering nucleic acids to cardiac tissue

Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo

Polyampholytes for delivering polyions to a cell

Compound containing a labile disulfide bond