James E Hagstrom

Reversibly masked polymers

Polyconjugates for in vivo delivery of polynucleotides

Method for single-step attachment of a label to target molecules

Intravenous delivery of polynucleotides to cells in mammalian limb

Delivery of molecules and complexes to mammalian cells in vivo

Membrane active heteropolymers

Membrane active heteropolymers

Endosomolytic poly(acrylate) polymers

Endosomolytic poly(vinyl ether) polymers

Endosomolytic Modified Poly(Alcohol) and Poly(Amine) Polymers

Reversibly Masked Polymers

Endosomolytic Poly-Beta-Aminoester Polymers

Process for delivery of polynucleotides to the prostate

Polyconjugates for in vivo delivery of polynucleotides

Chelating Compound for Drug Delivery

Inhibition of gene expression by delivery of polynucleotides to animal cells in vivo

Nucleic acid injected into hepatic vein lumen

Devices and processes for distribution of genetic material to mammalian limb

Compositions and methods for drug delivery using pH sensitive molecules

Polyampholytes for delivering polyions to a cell

Endosomolytic polymers

Micellar systems

Intravascular delivery of non-viral nucleic acid

Compositions and methods for drug delivery using pH sensitive molecules

Nucleic acid injected into hapatic vein lumen and delivered to primate liver

Compounds and processes for single-pot attachment of a label to nucleic acid

Micellar systems

Process of making a compound by forming a polymer from a template drug

Reversible modification of amine-containing compounds

Gene expression with covalently modified polynucleotides

Process for generating multilayered particles

Intravascular delivery of nucleic acid

pH-titratable polyampholytes for delivering polyions to a cell

Process of making a compound by forming a polymer from a template drug

In vivo inhibition of hepatitis B virus

Formation of polyampholytes in the presence of a polyion

Process of making a compound by forming a polymer from a template drug

Gene expression with covalently modified polynucleotides

Polymerized formamides for use in delivery of compounds to cells

Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo

Reversible modification of membrane interaction

Intravascular delivery of nucleic acid

Formation of polyampholytes in the presence of a polyion

Compositions and methods for drug delivery using pH sensitive molecules

Intravascular delivery of non-viral nucleic acid

Compositions and processes using siRNA, amphipathic compounds and polycations

Process of delivering a virally encapsulated polynucleotide or viral vector to a parenchymal cell via the vascular system

Compositions and methods for drug delivery using pH sensitive molecules

Polynucleotide complex delivery

Formation of polyampholytes in the presence of a polyion

Process for delivering nucleic acids to cardiac tissue

Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo

Polyampholytes for delivering polyions to a cell

Genetic vaccines for cancer therapy