Gary E. Schiltz

SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS

SUBSTITUTED PYRROLIDONES AND PIPERIDONES AS SMALL MOLECULE INHIBITORS OF EZH2 AND EED PROTEIN BINDING

SUBSTITUTED [1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE COMPOUNDS AND PROTEOLYSIS-TARGETING CHIMERIC DERIVATIVES THEREOF (PROTACS) THAT INDUCE DEGRADATION OF EMBRYONIC ECTODERM DEVELOPMENT (EED) PROTEIN

SUBSTITUTED 3-AMINO-5-PHENYLBENZAMIDE COMPOUNDS AS COVALENT INHIBITORS OF ENHANCER ZESTE HOMOLOG 2 (EZH2) AND PROTEOLYSIS-TARGETING CHIMERIC DERIVATIVES THEREOF (PROTACS) THAT INDUCE DEGRADATION OF EZH2

PROTEOLYSIS-TARGETING CHIMERIC MOLECULES (PROTACS) THAT INDUCE DEGRADATION OF C-MYC PROTEIN

Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of indoleamine 2,3-dioxygenase (IDO) protein

INHIBITORS OF THE INTERACTION BETWEEN TRIP8B AND HCN CHANNELS AND USES THEREOF FOR TREATING NEUROLOGICAL DISEASES AND DISORDERS

Substituted 3-amino-5-phenylbenzamide compounds as covalent inhibitors of enhancer zeste homolog 2 (EZH2) and proteolysis-targeting chimeric derivatives thereof (PROTACs) that induce degradation of EZH2

SMALL MOLECULE MODULATORS OF SIGMA-1 AND SIGMA-2 RECEPTORS AND USES THEREOF

Substituted [1,2,4]triazolo[4,3-c]pyrimidin-5-amines and proteolysis-targeting chimeric derivatives thereof (PROTACs) that induce degradation of embryonic ectoderm development (EED) protein

Substituted pyrrolidones and piperidones as small molecule inhibitors of EZH2 and EED protein binding

Substituted fused pyrrolo-diazepinones and uses thereof

Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of indoleamine 2,3-dioxygenase (IDO) protein

TARGETING PLECKSTRIN-2 FOR TREATING CANCER

Substituted heterocycles as c-MYC targeting agents

INHIBITORS OF TISSUE TRANSGLUTAMINASE 2 (TG2) AND USES THEREOF

Small molecules for disrupting the super elongation complex and inhibiting transcription elongation for cancer therapy

3-arylindazoles as selective MEK4 inhibitors

Substituted heterocycles as c-MYC targeting agents

Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of c-MYC protein

CXCR4 CHEMOKINE RECEPTOR MODULATORS

Substituted fused pyrrolo-diazepinones and uses thereof

Substituted heterocycles as c-MYC targeting agents

Therapeutic targeting of interleukin-1 receptor-associated kinase 4 (IRAK4) in cancers characterized by rearrangements in the mixed lineage leukemia gene (MLL-r)

Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (MNK1) and 2 (MNK2)

CXCR4 chemokine receptor modulators

SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS

Substituted aromatic N-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (Mnk1) and 2 (Mnk2)

Small molecule inhibitors of superoxide dismutase expression

3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members

Substituted pyrrolo[2,3-d]pyrimidines for the treatment of cancer and proliferative disorders