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Inventor profile of:

John Desjarlais

City:

Pasadena, California

Country:

United States

Published Applications:

139

Last publication date:

2026-03-19

Top Assignees for applications by John Desjarlais

The entities that hold a legal rights for patent applications filed by inventor Desjarlais John:

XENCOR, INC. 73 Monrovia, CA United States
Xencor, Inc. 16 Pasadena, CA United States
Genentech, Inc. 1 South San Francisco, CA United States
Xencor, Inc. 1 Pasasdena, CA United States

Recent patent applications by Desjarlais John

John Desjarlais from Pasadena, US has applied for patents for these inventions. The list has both pending applications and granted patents:

#1 | 2026-03-19

US20260078160A1

Chemistry; metallurgy

LAG-3 TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA Fc-FUSION PROTEINS AND LAG-3 ANTIGEN BINDING DOMAINS

#2 | 2025-10-30

US20250333519A1

Chemistry; metallurgy

BISPECIFIC CHECKPOINT INHIBITOR ANTIBODIES

#3 | 2025-10-02

US20250304724A1

Chemistry; metallurgy

HETERODIMERIC ANTIBODIES THAT BIND CD3 AND TUMOR ANTIGENS

#4 | 2025-04-10

US20250114440A1

Human necessities

Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions

#5 | 2025-04-03

US20250109215A1

Chemistry; metallurgy

HETERODIMERIC ANTIBODIES THAT BIND CD3 AND TUMOR ANTIGENS

#6 | 2025-04-03

US20250109214A1

Chemistry; metallurgy

HETERODIMERIC ANTIBODIES THAT BIND CD3 AND CD38

#7 | 2025-03-20

US20250092108A1

Chemistry; metallurgy

ENGINEERED IL-2 Fc FUSION PROTEINS

#8 | 2025-02-20

US20250057919A1

Human necessities

IL-15/IL-15RA HETERODIMERIC FC FUSION PROTEINS AND USES THEREOF

#9 | 2025-01-30

US20250034247A1

Chemistry; metallurgy

OPTIMIZED ANTIBODY VARIABLE REGIONS

#10 | 2025-01-09

US20250011440A1

Chemistry; metallurgy

Fc VARIANTS WITH ALTERED BINDING TO FcRn

#11 | 2024-09-05

US20240294593A1

Chemistry; metallurgy

PD-1 TARGETED IL-15/IL-15RALPHA FC FUSION PROTEINS WITH IMPROVED PROPERTIES

#12 | 2024-03-21

US20240092871A1

Chemistry; metallurgy

HETERODIMERIC PROTEINS

#13 | 2024-01-25

US20240026023A1

Chemistry; metallurgy

OPTIMIZED Fc VARIANTS

#14 | 2024-01-25

US20240026002A1

Chemistry; metallurgy

BISPECIFIC IMMUNOMODULATORY ANTIBODIES THAT BIND COSTIMULATORY AND CHECKPOINT RECEPTORS

#15 | 2023-12-14

US20230399401A1

Chemistry; metallurgy

OPTIMIZED ANTIBODY VARIABLE REGIONS

#16 | 2023-11-16

US20230365717A1

Chemistry; metallurgy

HETERODIMERIC ANTIBODIES THAT BIND CD3 AND TUMOR ANTIGENS

#17 | 2023-10-19

US20230331813A1

Chemistry; metallurgy

TIM-3 TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA Fc-FUSION PROTEINS AND TIM-3 ANTIGEN BINDING DOMAINS

#18 | 2023-09-07

US20230279154A1

Chemistry; metallurgy

NOVEL HETERODIMERIC PROTEINS

#19 | 2023-09-07

US20230279071A1

Chemistry; metallurgy

LAG-3 TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA Fc-FUSION PROTEINS AND LAG-3 ANTIGEN BINDING DOMAINS

#20 | 2023-07-13

US20230220081A1

Chemistry; metallurgy

BISPECIFIC HETERODIMERIC FUSION PROTEINS CONTAINING IL-15 - IL-15Ralpha Fc-FUSION PROTEINS AND IMMUNE CHECKPOINT ANTIBODY FRAGMENTS

#21 | 2023-05-18

US20230151095A1

Chemistry; metallurgy

BISPECIFIC ANTIBODIES THAT BIND TO B7H3 AND NKG2D

#22 | 2023-05-11

US20230146665A1

Chemistry; metallurgy

IL-18-FC FUSION PROTEINS

#23 | 2023-03-23

US20230086017A1

Chemistry; metallurgy

TRISPECIFIC ANTIBODIES

#24 | 2023-02-23

US20230059206A1

Chemistry; metallurgy

HETERODIMERIC PROTEINS

#25 | 2023-02-09

US20230041377A1

Chemistry; metallurgy

BISPECIFIC CHECKPOINT INHIBITOR ANTIBODIES

#26 | 2022-12-22

US20220403049A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and CD38

#27 | 2022-12-01

US20220380462A1

Chemistry; metallurgy

Optimized antibody variable regions

#28 | 2022-07-07

US20220213162A1

Chemistry; metallurgy

Engineered IL-2 Fc fusion proteins

#29 | 2022-06-30

US20220204624A1

Chemistry; metallurgy

Bispecific and monospecific antibodies using novel anti-PD-1 sequences

#30 | 2022-06-23

US20220195048A1

Chemistry; metallurgy

IL15/IL15Ralpha HETERODIMERIC Fc-FUSION PROTEINS

#31 | 2022-05-26

US20220162343A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#32 | 2022-02-10

US20220041757A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#33 | 2022-02-10

US20220040264A1

Human necessities

IL-15/IL-15RA heterodimeric Fc fusion proteins and uses thereof

#34 | 2021-10-07

US20210309762A1

Chemistry; metallurgy

Bispecific antibodies that bind to CD38 and CD3

#35 | 2021-09-16

US20210284754A1

Chemistry; metallurgy

HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFICATIONS

#36 | 2021-08-19

US20210253736A1

Chemistry; metallurgy

Heterodimeric antibodies that bind fibroblast activation protein

#37 | 2021-08-19

US20210253706A1

Chemistry; metallurgy

BISPECIFIC IMMUNOMODULATORY ANTIBODIES THAT BIND COSTIMULATORY AND CHECKPOINT RECEPTORS

#38 | 2021-07-29

US20210230243A1

Chemistry; metallurgy

PD-1 targeted IL-15/IL-15Rα Fc fusion proteins with improved properties

#39 | 2021-07-08

US20210205426A1

Human necessities

Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions

#40 | 2021-06-10

US20210171608A1

Chemistry; metallurgy

Heterodimeric proteins

#41 | 2021-06-03

US20210163627A1

Chemistry; metallurgy

Heterodimeric proteins

#42 | 2021-05-13

US20210139600A1

Chemistry; metallurgy

Optimized Fc variants

#43 | 2021-04-22

US20210115147A1

Chemistry; metallurgy

Fc VARIANTS WITH ALTERED BINDING TO FcRn

#44 | 2021-04-08

US20210102003A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#45 | 2021-04-08

US20210102002A1

Chemistry; metallurgy

HETERODIMERIC IgG-LIKE BISPECIFIC ANTIBODIES

#46 | 2021-04-01

US20210095030A1

Chemistry; metallurgy

BISPECIFIC IMMUNOMODULATORY ANTIBODIES THAT BIND COSTIMULATORY AND CHECKPOINT RECEPTORS

#47 | 2021-03-11

US20210070824A1

Chemistry; metallurgy

IL-7-FC-fusion proteins

#48 | 2020-10-29

US20200339624A1

Chemistry; metallurgy

MODULATION OF T CELLS WITH BISPECIFIC ANTIBODIES AND FC FUSIONS

#49 | 2020-07-09

US20200216559A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and PSMA

#50 | 2020-06-25

US20200199251A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and CD38

#51 | 2020-05-28

US20200165356A1

Chemistry; metallurgy

Heterodimeric antibodies that bind fibroblast activation protein

#52 | 2020-04-23

US20200123259A1

Chemistry; metallurgy

Bispecific heterodimeric fusion proteins containing IL-15-IL-15Ralpha Fc-fusion proteins and immune checkpoint antibody fragments

#53 | 2020-02-13

US20200048370A1

Chemistry; metallurgy

Heterodimeric proteins

#54 | 2020-02-06

US20200040083A1

Chemistry; metallurgy

IL15/IL15Ralpha HETERODIMERIC Fc-FUSION PROTEINS

#55 | 2019-12-26

US20190389954A1

Chemistry; metallurgy

Bispecific checkpoint inhibitor antibodies

#56 | 2019-12-26

US20190389933A1

Chemistry; metallurgy

PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof

#57 | 2019-12-19

US20190382495A1

Chemistry; metallurgy

Bispecific checkpoint inhibitor antibodies

#58 | 2019-12-05

US20190365861A1

Human necessities

IL-15/IL-15RA HETERODIMERIC FC FUSION PROTEINS AND USES THEREOF

#59 | 2019-11-28

US20190359684A1

Chemistry; metallurgy

TIM-3 targeted heterodimeric fusion proteins containing IL-15/IL-15RA Fc-fusion proteins and TIM-3 antigen binding domains

#60 | 2019-11-21

US20190352416A1

Chemistry; metallurgy

TRISPECIFIC ANTIBODIES

#61 | 2019-11-21

US20190352362A1

Chemistry; metallurgy

LAG-3 TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA Fc-FUSION PROTEINS AND LAG-3 ANTIGEN BINDING DOMAINS

#62 | 2019-09-05

US20190270816A1

Chemistry; metallurgy

Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors

#63 | 2019-09-05

US20190270810A1

Chemistry; metallurgy

Optimized antibody variable regions

#64 | 2019-08-29

US20190263909A1

Chemistry; metallurgy

Bispecific and monospecific antibodies using novel anti-PD-1 sequences

#65 | 2019-08-08

US20190241638A1

Chemistry; metallurgy

Engineered IL-2 Fc fusion proteins

#66 | 2019-07-04

US20190202938A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#67 | 2019-06-27

US20190194325A1

Chemistry; metallurgy

Modulation of T cells with bispecific antibodies and Fc fusions

#68 | 2019-03-07

US20190071512A1

Chemistry; metallurgy

Fc variants with increased affinity for FcγRIIc

#69 | 2019-01-17

US20190016778A1

Chemistry; metallurgy

Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains

#70 | 2018-12-20

US20180360981A1

Human necessities

NOVEL IMMUNOGLOBULIN VARIANTS

#71 | 2018-10-04

US20180282432A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#72 | 2018-08-09

US20180223000A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#73 | 2018-08-02

US20180215834A1

Chemistry; metallurgy

Heterodimeric proteins

#74 | 2018-07-26

US20180208668A1

Chemistry; metallurgy

OPTIMIZED Fc VARIANTS

#75 | 2018-07-19

US20180201686A1

Chemistry; metallurgy

RAPID CLEARANCE OF ANTIGEN COMPLEXES USING NOVEL ANTIBODIES

#76 | 2018-06-14

US20180162946A1

Chemistry; metallurgy

Fc VARIANTS WITH ALTERED BINDING TO FcRn

#77 | 2018-05-24

US20180142040A1

Chemistry; metallurgy

Heterodimeric proteins

#78 | 2018-05-10

US20180127501A1

Chemistry; metallurgy

Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors

#79 | 2018-05-03

US20180118836A1

Chemistry; metallurgy

Bispecific checkpoint inhibitor antibodies

#80 | 2018-05-03

US20180118828A1

Chemistry; metallurgy

Bispecific heterodimeric fusion proteins containing IL-15-IL-15Rα Fc-fusion proteins and PD-1 antibody fragments

#81 | 2018-05-03

US20180118805A1

Chemistry; metallurgy

IL15/IL15Rα heterodimeric Fc-fusion proteins

#82 | 2018-04-05

US20180094079A1

Chemistry; metallurgy

Bispecific antibodies that bind to CD38 and CD3

#83 | 2018-02-08

US20180037668A1

Chemistry; metallurgy

Heterodimeric proteins

#84 | 2017-11-09

US20170320947A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and PSMA

#85 | 2017-08-31

US20170247470A9

Chemistry; metallurgy

RAPID CLEARANCE OF ANTIGEN COMPLEXES USING NOVEL ANTIBODIES

#86 | 2017-06-15

US20170166655A1

Chemistry; metallurgy

NOVEL IMMUNOGLOBULIN VARIANTS

#87 | 2017-03-23

US20170081424A1

Chemistry; metallurgy

Heterodimeric antibodies to CD3 X CD123

#88 | 2017-03-23

US20170081420A1

Chemistry; metallurgy

Heterodimeric antibodies to CD3 X CD20

#89 | 2017-02-09

US20170037131A1

Chemistry; metallurgy

Modulation of T cells with bispecific antibodies and FC fusions

#90 | 2016-12-08

US20160355608A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#91 | 2016-12-08

US20160355600A1

Chemistry; metallurgy

Trispecific antibodies

#92 | 2016-12-01

US20160347837A1

Chemistry; metallurgy

OPTIMIZED Fc VARIANTS AND METHODS FOR THEIR GENERATION

#93 | 2016-12-01

US20160347825A1

Chemistry; metallurgy

Optimized Fc variants and methods for their generation

#94 | 2016-11-24

US20160340436A9

Chemistry; metallurgy

OPTIMIZED FC VARIANTS

#95 | 2016-11-03

US20160318993A1

Chemistry; metallurgy

Optimized Fc variants and methods for their generation

#96 | 2016-10-20

US20160304589A9

Chemistry; metallurgy

Optimized Fc variants

#97 | 2016-08-11

US20160229924A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and tumor antigens

#98 | 2016-07-28

US20160215063A1

Chemistry; metallurgy

Heterodimeric antibodies that bind CD3 and CD38

#99 | 2016-06-23

US20160176969A1

Chemistry; metallurgy

HETERODIMERIC ANTIBODIES INCLUDING BINDING TO CD8

#100 | 2016-03-10

US20160068588A1

Chemistry; metallurgy

ANTIBODIES WITH MODIFIED ISOELECTRIC POINTS AND IMMUNOFILTERING

InventorID:

298631 ⎘