Inventor profile of:

David M. Goldenberg

City:

Mendham, New Jersey

Country:

United States

Published Applications:

451

Last publication date:

2021-11-11

Top Assignees for applications by David M. Goldenberg

The entities that hold a legal rights for patent applications filed by inventor Goldenberg David M.:

Recent patent applications by Goldenberg David M.

David M. Goldenberg from Mendham, US has applied for patents for these inventions. The list has both pending applications and granted patents:

#1 | 2021-11-11
US20210346511A1
Human necessities

IMMUNOCONJUGATES WITH AN INTRACELLULARLY-CLEAVABLE LINKAGE

#2 | 2020-10-08
US20200316054A1
Human necessities

Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity

#3 | 2020-09-03
US20200276325A1
Human necessities

Immunoconjugates with an intracellularly-cleavable linkage

#4 | 2020-08-06
US20200246481A1
Human necessities

Antibody-drug conjugates and uses thereof

#5 | 2019-08-15
US20190248917A1
Chemistry; metallurgy

Combination of ABCG2 inhibitors with sacituzumab govitecan (IMMU-132) overcomes resistance to SN-38 in Trop-2 expressing cancers

#6 | 2019-07-11
US20190209703A1
Human necessities

Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer

#7 | 2019-06-13
US20190177427A1
Chemistry; metallurgy

Efficacy of anti-Trop-2-SN-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors

#8 | 2019-06-06
US20190167805A1
Human necessities

Immunoconjugates with an intracellularly-cleavable linkage

#9 | 2019-05-16
US20190142939A1
Human necessities

COMBINATION THERAPY FOR INDUCING IMMUNE RESPONSE TO DISEASE

#10 | 2019-03-21
US20190083621A1
Human necessities

RS7 Antibodies

#11 | 2019-03-07
US20190070308A1
Human necessities

Antibody-drug conjugates and uses thereof

#12 | 2019-01-31
US20190030175A1
Human necessities

Antibody-SN-38 immunoconjugates with a CL2A linker

#13 | 2019-01-17
US20190015405A1
Human necessities

Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity

#14 | 2018-11-08
US20180318439A1
Human necessities

Immunoconjugates with an intracellularly-cleavable linkage

#15 | 2018-10-18
US20180296689A1
Human necessities

NEOADJUVANT USE OF ANTIBODY-DRUG CONJUGATES

#16 | 2018-10-04
US20180280532A1
Human necessities

Subcutaneous administration of antibody-drug conjugates for cancer therapy

#17 | 2018-09-27
US20180271992A1
Human necessities

Treatment of high Trop-2 expressing triple negative breast cancer (TNBC) with sacituzumab govitecan (IMMU-132) overcomes homologous recombination repair (HRR) rescue mediated by Rad51

#18 | 2018-09-06
US20180250406A1
Human necessities

RS7 antibodies

#19 | 2018-07-05
US20180186898A1
Chemistry; metallurgy

Murine, chimeric, humanized or human anti-TNF-alpha antibodies

#20 | 2018-07-05
US20180185351A1
Human necessities

Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2

#21 | 2018-06-21
US20180171003A1
Chemistry; metallurgy

Chimeric and humanized anti-histone antibodies

#22 | 2018-06-14
US20180162945A1
Chemistry; metallurgy

Subcutaneous anti-HLA-DR monoclonal antibody for treatment of hematologic malignancies

#23 | 2018-06-14
US20180161440A1
Human necessities

Antibody-SN-38 immunoconjugates with a CL2A linker

#24 | 2018-05-31
US20180149657A1
Physics

Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells

#25 | 2018-05-17
US20180133322A1
Human necessities

RS7 antibodies

#26 | 2018-05-03
US20180118846A1
Chemistry; metallurgy

Disease therapy by inducing immune response to Trop-2 expressing cells

#27 | 2018-04-26
US20180110772A1
Human necessities

Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)

#28 | 2018-03-29
US20180085469A1
Human necessities

Antibody-SN-38 immunoconjugates with a CL2A linker

#29 | 2018-03-22
US20180079816A1
Chemistry; metallurgy

Multivalent Antibody Complexes Targeting IGF-1R Show Potent Toxicity Against Solid Tumors

#30 | 2018-02-22
US20180051085A1
Chemistry; metallurgy

Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1

#31 | 2018-01-25
US20180022796A1
Chemistry; metallurgy

Methods for treating ischemic stroke using chimeric and humanized anti-histone antibodies

#32 | 2017-12-21
US20170360770A1
Human necessities

Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers

#33 | 2017-11-23
US20170334996A1
Chemistry; metallurgy

FUSION PROTEINS CONTAINING RECOMBINANT CYTOTOXIC RNASES

#34 | 2017-11-16
US20170326238A1
Human necessities

CROSSLINKING OF CD22 BY EPRATUZUMAB TRIGGERS BCR SIGNALING AND CASPASE-DEPENDENT APOPTOSIS IN HEMATOPOIETIC CANCER CELLS

#35 | 2017-11-09
US20170320952A1
Chemistry; metallurgy

Isolated nucleic acid encoding an anti-IGF-1R antibody

#36 | 2017-11-02
US20170313781A1
Chemistry; metallurgy

Efficacy of anti-trop-2-SN-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors

#37 | 2017-10-05
US20170283511A1
Chemistry; metallurgy

Murine, chimeric, humanized or human anti-IL-6 antibodies

#38 | 2017-10-05
US20170283442A1
Chemistry; metallurgy

Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules

#39 | 2017-10-05
US20170281791A1
Human necessities

ANTI-TROP-2 ANTIBODY-DRUG CONJUGATES AND USES THEREOF

#40 | 2017-10-05
US20170281767A1
Human necessities

Combination therapy for inducing immune response to disease

#41 | 2017-09-28
US20170275375A1
Chemistry; metallurgy

Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors

#42 | 2017-09-28
US20170275363A1
Chemistry; metallurgy

Humanized anti-CD22 antibody

#43 | 2017-09-28
US20170274093A1
Human necessities

COMBINING ANTI-HLA-DR OR ANTI-TROP-2 ANTIBODIES WITH MICROTUBULE INHIBITORS, PARP INHIBITORS, BRUTON KINASE INHIBITORS OR PHOSPHOINOSITIDE 3-KINASE INHIBITORS SIGNIFICANTLY IMPROVES THERAPEUTIC OUTCOME IN CANCER

#44 | 2017-09-28
US20170274079A1
Human necessities

RS7 antibodies

#45 | 2017-09-21
US20170266316A1
Human necessities

Immunoconjugates with an intracellularly-cleavable linkage

#46 | 2017-09-21
US20170266310A1
Human necessities

PRO-DRUG FORM (P2PDOX) OF THE HIGHLY POTENT 2-PYRROLINODOXORUBICIN CONJUGATED TO ANTIBODIES FOR TARGETED THERAPY OF CANCER

#47 | 2017-09-21
US20170266281A1
Human necessities

Subcutaneous administration of anti-CD74 antibody for systemic lupus erythematosus

#48 | 2017-09-14
US20170260287A1
Chemistry; metallurgy

Stable compositions of high-concentration allotype-selected antibodies for small-volume administration

#49 | 2017-08-31
US20170247417A1
Chemistry; metallurgy

T-cell redirecting bispecific antibodies for treatment of disease

#50 | 2017-08-31
US20170246291A1
Human necessities

T20 constructs for anti-HIV (human immunodeficiency virus) therapy and/or vaccines

#51 | 2017-08-24
US20170239368A1
Human necessities

Immunoconjugates with an intracellularly-cleavable linkage

#52 | 2017-08-10
US20170226219A1
Chemistry; metallurgy

Disease therapy by inducing immune response to Trop-2 expressing cells

#53 | 2017-08-10
US20170226205A1
Chemistry; metallurgy

Therapeutic use of anti-CD22 antibodies for inducing trogocytosis

#54 | 2017-08-10
US20170224837A1
Human necessities

COMBINATION OF ABCG2 INHIBITORS WITH SACITUZUMAB GOVITECAN (IMMU-132) OVERCOMES RESISTANCE TO SN-38 IN TROP-2 EXPRESSING CANCERS

#55 | 2017-08-03
US20170218059A1
Chemistry; metallurgy

Methods for treating thrombosis using chimeric and humanized anti-histone antibodies

#56 | 2017-08-03
US20170216447A1
Human necessities

Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers

#57 | 2017-07-27
US20170209594A1
Human necessities

Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors

#58 | 2017-06-22
US20170173167A1
Human necessities

Methods and Compositions for Treatment of Human Immunodeficiency Virus Infection with Conjugated Antibodies or Antibody Fragments

#59 | 2017-06-15
US20170166651A1
Chemistry; metallurgy

Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology

#60 | 2017-06-15
US20170165370A1
Human necessities

Antibody-SN-38 immunoconjugates with a CL2A linker

#61 | 2017-06-01
US20170152315A1
Chemistry; metallurgy

Anti-CD19 Antibodies

#62 | 2017-06-01
US20170151356A1
Human necessities

Camptothecin Conjugates of Anti-CD22 Antibodies for Treatment of B Cell Diseases

#63 | 2017-05-18
US20170137534A1
Chemistry; metallurgy

Anti-Pancreatic Cancer Antibodies

#64 | 2017-05-04
US20170121692A1
Chemistry; metallurgy

Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses

#65 | 2017-03-30
US20170088635A1
Chemistry; metallurgy

Dock-and-Lock (DNL) Complexes for Therapeutic and Diagnostic Use

#66 | 2017-03-30
US20170088619A1
Chemistry; metallurgy

Antibody-Based Depletion of Antigen-Presenting Cells and Dendritic Cells

#67 | 2017-03-09
US20170066828A1
Chemistry; metallurgy

Humanized anti-HLA-DR antibodies

#68 | 2017-03-02
US20170056516A1
Human necessities

Tetrameric cytokines with improved biological activity

#69 | 2017-02-09
US20170035908A1
Human necessities

Detection of Early-Stage Pancreatic Adenocarcinoma

#70 | 2017-02-02
US20170028081A1
Human necessities

Immunoconjugates with an intracellularly-cleavable linkage

#71 | 2017-01-26
US20170022274A1
Chemistry; metallurgy

T-cell redirecting bispecific antibodies for treatment of disease

#72 | 2017-01-26
US20170021017A1
Human necessities

Combination therapy for inducing immune response to disease

#73 | 2017-01-19
US20170014527A1
Human necessities

Antibody-drug conjugates and uses thereof

#74 | 2017-01-19
US20170014403A1
Human necessities

Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity

#75 | 2017-01-12
US20170007727A1
Human necessities

METHODS OF IMAGING WITH Ga-68 LABELED MOLECULES

#76 | 2017-01-05
US20170000896A1
Human necessities

Pro-drug form (P2PDox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer

#77 | 2016-12-29
US20160376366A1
Chemistry; metallurgy

Humanized anti-CD22 antibody

#78 | 2016-12-29
US20160375108A1
Human necessities

Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity

#79 | 2016-12-22
US20160368986A1
Chemistry; metallurgy

Therapeutic use of anti-CD22 antibodies for inducing trogocytosis

#80 | 2016-12-15
US20160361435A1
Human necessities

PEGylation by the dock and lock (DNL) technique

#81 | 2016-12-15
US20160361405A1
Human necessities

Dock-and-Lock (DNL) Vaccines for Cancer Therapy

#82 | 2016-12-15
US20160361360A1
Human necessities

DISEASE THERAPY WITH CHIMERIC ANTIGEN RECEPTOR (CAR) CONSTRUCTS AND T CELLS (CAR-T) OR NK CELLS (CAR-NK) EXPRESSING CAR CONSTRUCTS

#83 | 2016-12-08
US20160355591A1
Chemistry; metallurgy

SUBCUTANEOUS ANTI-HLA-DR MONOCLONAL ANTIBODY FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES

#84 | 2016-12-01
US20160347857A1
Chemistry; metallurgy

ANTIBODIES REACTIVE WITH AN EPITOPE LOCATED IN THE N-TERMINAL REGION OF MUC5AC COMPRISING CYSTEINE-RICH SUBDOMAIN 2 (CYS2)

#85 | 2016-12-01
US20160346380A1
Human necessities

T20 constructs for anti-HIV (human immunodeficiency virus) therapy and/or vaccines

#86 | 2016-11-24
US20160340443A1
Chemistry; metallurgy

Multimeric Complexes with Improved in Vivo Stability, Pharmacokinetics and Efficacy

#87 | 2016-11-17
US20160333098A1
Chemistry; metallurgy

Class of monospecific and bispecific humanized antibodies that target the insulin-like growth factor type I receptor (IGF-1R)

#88 | 2016-11-03
US20160319020A1
Chemistry; metallurgy

Anti-CD19 antibodies

#89 | 2016-10-27
US20160313339A1
Physics

Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells

#90 | 2016-10-27
US20160311931A1
Chemistry; metallurgy

BISPECIFIC ANTIBODIES THAT NEUTRALIZE BOTH TNF-ALPHA AND IL-6: NOVEL THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASE

#91 | 2016-10-20
US20160304611A1
Chemistry; metallurgy

COMBINATION THERAPY FOR TREATING ADULT PATIENTS WITH RELAPSED/REFRACTORY CD22+ B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

#92 | 2016-10-20
US20160303253A1
Human necessities

Antibody-SN-38 immunoconjugates with a CL2A linker

#93 | 2016-10-13
US20160296648A1
Human necessities

Y-90-LABELED ANTI-CD22 ANTIBODY (EPRATUZUMAB TETRAXETAN) IN REFRACTORY/RELAPSED ADULT CD22+ B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

#94 | 2016-10-13
US20160296633A1
Human necessities

Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer

#95 | 2016-10-06
US20160287732A1
Human necessities

TUMOR THERAPY BY BISPECIFIC ANTIBODY PRETARGETING

#96 | 2016-09-29
US20160279239A1
Human necessities

SUBCUTANEOUS ADMINISTRATION OF ANTI-CD74 ANTIBODY FOR SYSTEMIC LUPUS ERYTHEMATOSUS AND AUTOIMMUNE DISEASE

#97 | 2016-09-15
US20160264678A1
Chemistry; metallurgy

Disease therapy by inducing immune response to Trop-2 expressing cells

#98 | 2016-09-08
US20160257947A9
Chemistry; metallurgy

Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity

#99 | 2016-09-08
US20160256562A1
Human necessities

Antibody-SN-38 immunoconjugates with a CL2A linker

#100 | 2016-09-01
US20160251444A1
Chemistry; metallurgy

THERAPEUTIC USE OF ANTI-CD22 ANTIBODIES FOR INDUCING TROGOCYTOSIS

InventorID:

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