Patent Applications published on Aug 9, 2012 - page 15

#4201
US20120202793A1
Chemistry; metallurgy

RHO KINASE INHIBITORS

#4202
US20120202794A1
Chemistry; metallurgy

COMPOUNDS

#4203
US20120202795A1
Chemistry; metallurgy

SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP)

#4204 ✅ Patent 9,457,018 granted on 2016-10-04
US20120202796A1
Human necessities

Method for combating adverse effects arising from antipsychotic treatment

#4205 ✅ Patent 8,314,092 granted on 2012-11-20
US20120202797A1
Chemistry; metallurgy

Substituted [(5-pyrrolo[2,1-c][1,4]benzodiazepin-11-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid compounds as dual activity H1 inverse agonists/5-HTantagonists

#4206 ✅ Patent 8,883,777 granted on 2014-11-11
US20120202798A1
Human necessities

Compositions controlling pH range of release and/or release rate

#4207
US20120202799A1
Chemistry; metallurgy

Condensed Azepine Derivatives As Bromodomain Inhibitors

#4208 ✅ Patent 8,642,610 granted on 2014-02-04
US20120202800A1
Chemistry; metallurgy

Dual small molecule inhibitors of cancer and angiogenesis

#4209
US20120202801A1
Human necessities

METHODS FOR TREATING BREAST CANCER

#4210 ✅ Patent 8,877,749 granted on 2014-11-04
US20120202802A1
Chemistry; metallurgy

Spirocyclic compounds as modulators of chemokine receptor activity

#4211 ✅ Patent 8,404,680 granted on 2013-03-26
US20120202803A1
Chemistry; metallurgy

N-[3-(5-amino-3,3a,7,7a-tetrahydro-1H-2,4-dioxa-6-aza-inden-7-yl)-phenyl]-amides as BACE1 and/or BACE2 inhibitors

#4212 ✅ Patent 9,079,914 granted on 2015-07-14
US20120202804A1
Chemistry; metallurgy

Fused aminodihydro-oxazine derivatives

#4213 ✅ Patent 8,569,296 granted on 2013-10-29
US20120202805A1
Chemistry; metallurgy

PI3K (delta) selective inhibitors

#4214
US20120202806A1
Chemistry; metallurgy

Novel Pyrimidine- And Triazine-Hepcidine Antagonists

#4215 ✅ Patent 8,759,343 granted on 2014-06-24
US20120202807A1
Chemistry; metallurgy

Azabicycloalkane derivatives, preparation thereof and use thereof in therapy

#4216 ✅ Patent 8,288,380 granted on 2012-10-16
US20120202808A1
Chemistry; metallurgy

Thiophenediamine derivative having urea structure

#4217 ✅ Patent 8,877,761 granted on 2014-11-04
US20120202809A1
Chemistry; metallurgy

N-pyrimidin-4-yl-3-amino-pyrrolo[3,4-c]pyrazole derivatives as PKC kinase inhibitors

#4218 ✅ Patent 8,835,689 granted on 2014-09-16
US20120202810A1
Chemistry; metallurgy

Substituted 4-aminocyclohexane derivatives

#4219
US20120202811A1
Human necessities

NOVEL COMPOUNDS

#4220 ✅ Patent 8,440,664 granted on 2013-05-14
US20120202812A1
Chemistry; metallurgy

Heteroaryls and uses thereof

#4221 ✅ Patent 8,329,736 granted on 2012-12-11
US20120202813A1
Chemistry; metallurgy

Triazole compounds that modulate HSP90 activity

#4222
US20120202814A1
Chemistry; metallurgy

COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF

#4223 ✅ Patent 8,921,360 granted on 2014-12-30
US20120202815A1
Chemistry; metallurgy

Heterobicycle-substituted azolyl benzene fungicides

#4224 ✅ Patent 8,378,118 granted on 2013-02-19
US20120202816A1
Chemistry; metallurgy

Pyrazole-based thyroid receptor compounds

#4225 ✅ Patent 8,518,973 granted on 2013-08-27
US20120202817A1
Chemistry; metallurgy

Compounds having 4-pyridylalkylthio group as a substituent

#4226
US20120202818A1
Human necessities

UREIDOPHENYL SUBSTITUTED TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS

#4227
US20120202819A1
Human necessities

COMBINATION THERAPY USING A BETA 3 ADRENERGIC RECEPTOR AGONISTS AND AN ANTIMUSCARINIC AGENT

#4228
US20120202820A1
Human necessities

PHARMACEUTICAL COMPOSITION HAVING THE ACTIVE SUBSTANCES METFORMIN AND SITAGLIPTIN OR VILDAGLIPTIN

#4229 ✅ Patent 9,695,191 granted on 2017-07-04
US20120202821A1
Chemistry; metallurgy

Conformationally constrained, fully synthetic macrocyclic compounds

#4230
US20120202822A1
Human necessities

COMBINATION

#4231
US20120202823A1
Chemistry; metallurgy

Multi-API Loading Prodrugs

#4232 ✅ Patent 8,293,750 granted on 2012-10-23
US20120202824A1
Chemistry; metallurgy

Pyrazines as delta opioid receptor modulators

#4233
US20120202825A1
Human necessities

Soluble Salts of Thieno [2,3-d] Pyrimidine Derivatives

#4234 ✅ Patent 8,957,082 granted on 2015-02-17
US20120202826A1
Chemistry; metallurgy

Tetrahydropyrrolopyrimidinediones and their use in therapy

#4235 ✅ Patent 8,552,001 granted on 2013-10-08
US20120202827A1
Chemistry; metallurgy

Sulfoxide derivatives for the treatment of tumors

#4236 ✅ Patent 9,139,594 granted on 2015-09-22
US20120202828A1
Chemistry; metallurgy

Fused aminodihydropyrimidone derivatives

#4237 ✅ Patent 8,912,201 granted on 2014-12-16
US20120202829A1
Chemistry; metallurgy

6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders

#4238 ✅ Patent 8,987,442 granted on 2015-03-24
US20120202830A1
Human necessities

Deuterium-substituted xanthine derivatives and methods of use

#4239
US20120202831A1
Human necessities

Pharmaceutical Formulation

#4240 ✅ Patent 9,101,632 granted on 2015-08-11
US20120202832A1
Chemistry; metallurgy

Kinase inhibitors, prodrug forms thereof and their use in therapy

#4241 ✅ Patent 8,445,504 granted on 2013-05-21
US20120202833A1
Human necessities

Tricyclic pyrazolopyrimidine derivatives

#4242 ✅ Patent 8,507,533 granted on 2013-08-13
US20120202834A1
Chemistry; metallurgy

Glucagon receptor modulators

#4243 ✅ Patent 8,796,298 granted on 2014-08-05
US20120202835A1
Human necessities

Combination of a B-Raf inhibitor: N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1- dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide and the Akt inhibitor: N-{ (1S)-2-amino-1-[(3- fluorophenyl)methyl]ethyl}-5-chIoro-4-(4-chIoro- 1 -methyl- 1 H-pyrazol-5-yl)-2-10 thiophenecarboxamide useful in the treatment of cancer

#4244
US20120202836A1
Human necessities

METHOD OF TREATING PROLIFERATIVE DISORDERS AND OTHER PATHOLOGICAL CONDITIONS MEDIATED BY BCR-ABL, C-KIT, DDR1, DDR2 OR PDGF-R KINASE ACTIVITY

#4245
US20120202837A1
Chemistry; metallurgy

SPIROCYCLIC PIPERIDINE DERIVATIVES USEFUL AS RENIN INHIBITORS

#4246
US20120202838A1
Human necessities

DRUG FORMULATIONS

#4247
US20120202839A1
Human necessities

METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS

#4248
US20120202840A1
Human necessities

Use of Flubendazole and Vinca Alkaloids for Treatment of Hematological Diseases

#4249 ✅ Patent 9,402,802 granted on 2016-08-02
US20120202841A1
Human necessities

Topical compositions comprising ascomycins

#4250 ✅ Patent 8,884,017 granted on 2014-11-11
US20120202842A1
Chemistry; metallurgy

2-heteroarylcarboxylic acid amides

#4251
US20120202843A1
Physics

H3K27me3 and Cancer

#4252 ✅ Patent 8,633,217 granted on 2014-01-21
US20120202844A1
Chemistry; metallurgy

Crystal forms of kinase inhibitors

#4253 ✅ Patent 8,377,911 granted on 2013-02-19
US20120202845A1
Chemistry; metallurgy

Diuretics

#4254
US20120202846A1
Human necessities

MOLECULAR TARGET OF NEUROTOXICITY

#4255
US20120202847A1
Chemistry; metallurgy

Novel Tetrahydroisoquinoline Compounds

#4256 ✅ Patent 8,497,285 granted on 2013-07-30
US20120202848A1
Chemistry; metallurgy

Therapy of autoimmune colitis using a TIP60 inhibitor

#4257
US20120202849A1
Human necessities

PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT/PROPHYLAXIS OF NON-ALCOHOLIC FATTY LIVER DISEASE

#4258 ✅ Patent 8,691,844 granted on 2014-04-08
US20120202850A1
Human necessities

Method for treating thrombosis and inhibiting platelet aggregation with 21-(S)-argatroban

#4259 ✅ Patent 8,829,193 granted on 2014-09-09
US20120202851A1
Chemistry; metallurgy

PIM kinase inhibitors and methods of their use

#4260 ✅ Patent 8,987,310 granted on 2015-03-24
US20120202852A1
Chemistry; metallurgy

Heterocycle amide T-type calcium channel antagonists

#4261 ✅ Patent 8,653,112 granted on 2014-02-18
US20120202853A1
Chemistry; metallurgy

Substituted pyrazoles as estrogen receptor ligands

#4262 ✅ Patent 8,492,437 granted on 2013-07-23
US20120202854A1
Chemistry; metallurgy

4-substituted phenoxyphenylacetic acid derivatives

#4263
US20120202855A1
Human necessities

METHODS FOR TREATING HYPERLIPIDEMIA WITH INTERMEDIATE RELEASE NICOTINIC ACID COMPOSITIONS HAVING UNIQUE BIOPHARMACEUTICAL CHARACTERISTICS

#4264
US20120202856A1
Chemistry; metallurgy

SUBSTITUTED BENZIMDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS

#4265 ✅ Patent 8,710,087 granted on 2014-04-29
US20120202857A1
Chemistry; metallurgy

Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents

#4266 ✅ Patent 8,268,349 granted on 2012-09-18
US20120202858A1
Human necessities

Solid pharmaceutical dosage form

#4267 ✅ Patent 8,754,116 granted on 2014-06-17
US20120202859A1
Chemistry; metallurgy

Macrocyclic inhibitors of hepatitis C virus

#4268 ✅ Patent 9,102,636 granted on 2015-08-11
US20120202860A2
Chemistry; metallurgy

Analgesic compounds, compositions, and uses thereof

#4269 ✅ Patent 8,710,243 granted on 2014-04-29
US20120202861A1
Chemistry; metallurgy

Estrogen receptor ligands

#4270 ✅ Patent 8,377,978 granted on 2013-02-19
US20120202862A1
Human necessities

Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors

#4271
US20120202863A1
Human necessities

Compositions and methods for treatment of glaucoma

#4272
US20120202864A1
Human necessities

Compositions and Methods for Treatment of Glaucoma

#4273
US20120202865A1
Chemistry; metallurgy

SUBSTITUTED-ARYL-(IMIDAZOLE)-METHYL)-PHENYL COMPOUNDS AS SUBTYPE SELECTIVE MODULATORS OF ALPHA 2B AND/OR ALPHA 2C ADRENERGIC RECEPTORS

#4274
US20120202866A1
Human necessities

BUCCAL, POLAR AND NON-POLAR SPRAY CONTAINING ONDANSETRON

#4275 ✅ Patent 8,357,635 granted on 2013-01-22
US20120202867A1
Chemistry; metallurgy

Microbiocides

#4276 ✅ Patent 8,519,154 granted on 2013-08-27
US20120202868A1
Chemistry; metallurgy

Method for treatment of bronchial asthma

#4277 ✅ Patent 8,513,439 granted on 2013-08-20
US20120202869A1
Human necessities

Antidepressant oral pharmaceutical compositions

#4278 ✅ Patent 8,962,583 granted on 2015-02-24
US20120202870A1
Human necessities

Treatment of inflammatory diseases using miR-124

#4279 ✅ Patent 8,569,256 granted on 2013-10-29
US20120202871A1
Human necessities

Cationic lipids and methods for the delivery of therapeutic agents

#4280 ✅ Patent 8,957,039 granted on 2015-02-17
US20120202872A1
Chemistry; metallurgy

Methods and compositions for the diagnosis and prognosis of cervical intraepithelial neoplasia and cervical cancer

#4281 ✅ Patent 9,487,777 granted on 2016-11-08
US20120202873A1
Chemistry; metallurgy

RNAi probes targeting cancer-related proteins

#4282 ✅ Patent 8,623,643 granted on 2014-01-07
US20120202874A1
Chemistry; metallurgy

Antisense oligonucleotide modulation of STAT3 expression

#4283
US20120202875A1
Physics

Method Of Treatment

#4284
US20120202876A1
Human necessities

METHODS OF TREATING DISEASES WITH PROANTHOCYANIDIN OLIGOMERS SUCH AS CROFELEMER

#4285
US20120202877A1
Human necessities

ANTI-INFLUENZA AGENTS

#4286 ✅ Patent 9,532,969 granted on 2017-01-03
US20120202878A1
Human necessities

Method for treating psoriasis

#4287 ✅ Patent 8,324,275 granted on 2012-12-04
US20120202879A1
Human necessities

Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy

#4288 ✅ Patent 8,263,650 granted on 2012-09-11
US20120202880A1
Human necessities

Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy

#4289
US20120202881A1
Human necessities

Novel NIDDM Regimen

#4290 ✅ Patent 8,871,811 granted on 2014-10-28
US20120202882A1
Human necessities

Permeation enhancers for topical formulations

#4291
US20120202883A1
Human necessities

EFFECTS OF IDH1 AND IDH2 MUTATIONS ON THE CELLULAR METABOLOME

#4292
US20120202884A1
Human necessities

INHIBITORS OF CXCR1/2 AS ADJUVANTS IN THE TRANSPLANT OF PANCREATIC ISLETS

#4293
US20120202885A1
Human necessities

METHODS, ASSAYS AND COMPOSITIONS FOR TREATING RETINOL-RELATED DISEASES

#4294 ✅ Patent 8,632,760 granted on 2014-01-21
US20120202886A1
Human necessities

Method of enhancing hair growth

#4295 ✅ Patent 8,716,530 granted on 2014-05-06
US20120202887A1
Chemistry; metallurgy

Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof

#4296
US20120202888A1
Human necessities

BIOMARKERS OF PROSTATE CANCER AND PREDICTING MORTALITY

#4297
US20120202889A1
Human necessities

PRODUCTION METHOD FOR ASTAXANTHIN-CONTAINING COMPOSITION

#4298
US20120202890A1
Chemistry; metallurgy

POLYMER-CARBOHYDRATE-LIPID CONJUGATES

#4299
US20120202891A1
Human necessities

Cannabinoid-Containing Compositions and Methods for Their Use

#4300
US20120202892A1
Human necessities

Cannabinoid-Containing Compositions and Methods for Their Use

#4301 ✅ Patent 9,932,446 granted on 2018-04-03
US20120202893A1
Chemistry; metallurgy

Method of manufacturing a purified product of alkyl-modified polydimethylsiloxane, a cosmetic raw material, and cosmetics

#4302
US20120202894A1
Human necessities

Rapidly Soluble Solid Pharmaceutical Preparations Containing Amphiphilic Copolymers Based On Polyethers In Combination With Hydrophilic Polymers

#4303
US20120202895A1
Chemistry; metallurgy

PASTE COMPOSITION AND COSMETIC CONTAINING IT

#4304 ✅ Patent 9,102,828 granted on 2015-08-11
US20120202896A1
Chemistry; metallurgy

Composition including a copolyamide and a cross-linked polyolefin

#4305
US20120202897A1
Performing operations; transporting

METHOD OF PURIFYING A GAS

#4306
US20120202898A1
Performing operations; transporting

METHOD FOR OBTAINING A MULTIMETALLIC SULFUREOUS CATALYST AND USE THEREOF IN A METHOD FOR PRODUCING HIGHER ALCOHOLS BY CATALYTIC CONVERSION OF SYNTHESIS GAS

#4307 ✅ Patent 8,975,304 granted on 2015-03-10
US20120202899A1
Chemistry; metallurgy

Production of hydrocarbons

#4308 ✅ Patent 8,664,283 granted on 2014-03-04
US20120202900A1
Performing operations; transporting

Purification of acetic acid product streams

#4309 ✅ Patent 8,592,352 granted on 2013-11-26
US20120202901A1
Chemistry; metallurgy

Cement compositions comprising particulate foamed elastomers and associated methods

#4310
US20120202902A1
Chemistry; metallurgy

FOAMING AGENT FOR PLASTICS

#4311 ✅ Patent 9,290,604 granted on 2016-03-22
US20120202903A1
Chemistry; metallurgy

NPE-free emulsifiers for water-blown polyurethane spray foam

#4312 ✅ Patent 10,113,046 granted on 2018-10-30
US20120202904A1
Chemistry; metallurgy

Tetrafluorobutene blowing agent compositions for polyurethane foams

#4313 ✅ Patent 9,174,914 granted on 2015-11-03
US20120202905A1
Chemistry; metallurgy

Nanoscale β-nucleating agent for polypropylene

#4314 ✅ Patent 9,376,520 granted on 2016-06-28
US20120202906A1
Chemistry; metallurgy

Polytetrafluoroethylene aqueous emulsion and process for its production, polytetrafluoroethylene aqueous dispersion obtainable by using such an aqueous emulsion, polytetrafluoroethylene fine powder, and stretched porous material

#4315
US20120202907A1
Chemistry; metallurgy

LIGNIN BASED POLYOL FROM BLACK LIQUOR AND GLYCERINE

#4316
US20120202908A1
Chemistry; metallurgy

PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM

#4317 ✅ Patent 8,815,969 granted on 2014-08-26
US20120202909A1
Chemistry; metallurgy

Plant oil-based UV-curable coating

#4318
US20120202910A1
Physics

METHOD FOR PRODUCING POLYBUTADIENE

#4319 ✅ Patent 8,940,808 granted on 2015-01-27
US20120202911A1
Chemistry; metallurgy

Curable coating agent composition

#4320
US20120202912A1
Chemistry; metallurgy

SURFACE TREATMENT BY PHOTOPOLYMERISATION TO OBTAIN BIOCIDAL PROPERTIES

#4321 ✅ Patent 8,703,840 granted on 2014-04-22
US20120202913A1
Human necessities

Dental adhesive material kit

#4322 ✅ Patent 9,624,318 granted on 2017-04-18
US20120202914A1
Chemistry; metallurgy

Matting agent for UV varnishes

#4323 ✅ Patent 8,742,019 granted on 2014-06-03
US20120202915A1
Chemistry; metallurgy

Crosslinked polyolefin polymer blends

#4324 ✅ Patent 8,969,429 granted on 2015-03-03
US20120202916A1
Physics

Low-tack, hydrophobic ophthalmic device materials

#4325 ✅ Patent 8,877,830 granted on 2014-11-04
US20120202917A1
Chemistry; metallurgy

Stress relief for crosslinked polymers

#4326 ✅ Patent 8,399,577 granted on 2013-03-19
US20120202918A1
Chemistry; metallurgy

Curable epoxy resin composition

#4327 ✅ Patent 8,710,120 granted on 2014-04-29
US20120202919A1
Chemistry; metallurgy

Cross-linkable compositions

#4328 ✅ Patent 8,524,834 granted on 2013-09-03
US20120202920A1
Chemistry; metallurgy

Coating compositions containing tetramethyl cyclobutanediol

#4329 ✅ Patent 8,278,373 granted on 2012-10-02
US20120202921A1
Chemistry; metallurgy

Thermoset nanocomposite particles, processing for their production, and their use in oil and natural gas drilling applications

#4330 ✅ Patent 9,018,282 granted on 2015-04-28
US20120202922A1
Chemistry; metallurgy

Homogenous dispensing process for an epoxy-composition with high filler content

#4331 ✅ Patent 10,173,902 granted on 2019-01-08
US20120202923A1
Chemistry; metallurgy

Amorphous silica and process for producing same

#4332
US20120202924A1
Performing operations; transporting

SHEET CONTAINING RICE BRAN AND GIFT-SET TRAY EMPLOYING SAME

#4333 ✅ Patent 8,507,588 granted on 2013-08-13
US20120202925A1
Chemistry; metallurgy

PHBV/ground bone meal and pumice powder engineered biobased composite materials for construction

#4334 ✅ Patent 8,916,699 granted on 2014-12-23
US20120202926A1
Chemistry; metallurgy

Cellulose resin and method for producing the same

#4335 ✅ Patent 8,313,576 granted on 2012-11-20
US20120202927A1
Chemistry; metallurgy

Preparing and dispersing surface-modified colour pigments

#4336 ✅ Patent 8,754,173 granted on 2014-06-17
US20120202928A1
Chemistry; metallurgy

Method for continuously producing polyester mixtures

#4337 ✅ Patent 9,006,335 granted on 2015-04-14
US20120202929A1
Performing operations; transporting

Rubber composition for tire tread and pneumatic tire

#4338 ✅ Patent 8,723,153 granted on 2014-05-13
US20120202930A1
Electricity

Formulations for voltage switchable dielectric materials having a stepped voltage response and methods for making the same

#4339 ✅ Patent 8,501,845 granted on 2013-08-06
US20120202931A1
Chemistry; metallurgy

Flowable polyesters with hydrolysis resistance

#4340 ✅ Patent 8,263,702 granted on 2012-09-11
US20120202932A1
Physics

Fuser coating composition and method of manufacture

#4341 ✅ Patent 8,389,632 granted on 2013-03-05
US20120202933A1
Chemistry; metallurgy

Co-continuous heterophase polymer compositions containing high melt strength polypropylene for extrusion coating

#4342 ✅ Patent 8,692,031 granted on 2014-04-08
US20120202934A1
Chemistry; metallurgy

Method for preparing polyamine compounds

#4343 ✅ Patent 8,975,330 granted on 2015-03-10
US20120202935A1
Chemistry; metallurgy

Coating composition

#4344 ✅ Patent 8,445,110 granted on 2013-05-21
US20120202936A1
Chemistry; metallurgy

Water-sensitive film containing thermoplastic polyurethanes

#4345
US20120202937A1
Chemistry; metallurgy

LOW MOLECULAR WEIGHT PHOSPHORUS-CONTAINING POLYACRYLIC ACIDS AND USE THEREOF AS DISPERSANTS

#4346
US20120202938A1
Chemistry; metallurgy

FLUOROELASTOMER PARTS FOR OIL AND GAS EXPLORATION AND PRODUCTION

#4347
US20120202939A1
Chemistry; metallurgy

HEAT RESISTANT FLUOROELASTOMER ROTARY SHAFT LIP SEALS

#4348 ✅ Patent 8,586,663 granted on 2013-11-19
US20120202940A1
Chemistry; metallurgy

Polymer composition comprising polyamide and ionomer

#4349 ✅ Patent 8,609,757 granted on 2013-12-17
US20120202941A1
Chemistry; metallurgy

Cationic cross-linked polymers in water-in-water polymer dispersions

#4350 ✅ Patent 9,029,478 granted on 2015-05-12
US20120202942A1
Chemistry; metallurgy

High clarity polyethylene films

#4351
US20120202943A1
Chemistry; metallurgy

FLOWABLE POLYESTERS WITH POLYESTER ELASTOMERS

#4352 ✅ Patent 9,045,635 granted on 2015-06-02
US20120202944A1
Chemistry; metallurgy

Polylactic acid stereocomplex, method for production thereof, and nucleating agent for polylactic acid resin

#4353
US20120202945A1
Chemistry; metallurgy

POLYURETHANES AND USE THEREOF

#4354
US20120202946A1
Chemistry; metallurgy

Process for the isolation of sulfonyl fluoride polymers and polymers obtained therefrom

#4355 ✅ Patent 8,586,674 granted on 2013-11-19
US20120202947A1
Chemistry; metallurgy

Copolymer rubber composition, molded product, and automotive sealant

#4356 ✅ Patent 9,284,590 granted on 2016-03-15
US20120202948A1
Chemistry; metallurgy

Monodisperse random coil proteins and bioconjugates thereof

#4357 ✅ Patent 9,447,219 granted on 2016-09-20
US20120202949A1
Chemistry; metallurgy

Impact modified monovinylidene aromatic polymer having low rubber crosslinking

#4358 ✅ Patent 8,426,527 granted on 2013-04-23
US20120202950A1
Chemistry; metallurgy

Crosslinkable fluororubber composition and crosslinked rubber article

#4359 ✅ Patent 8,252,873 granted on 2012-08-28
US20120202951A1
Chemistry; metallurgy

Process for the production of a superabsorbent polymer

#4360 ✅ Patent 9,751,958 granted on 2017-09-05
US20120202952A1
Chemistry; metallurgy

Use of heating steam condensate for producing water-absorbent polymer particles

#4361 ✅ Patent 8,734,574 granted on 2014-05-27
US20120202953A1
Performing operations; transporting

Gas separation membrane

#4362 ✅ Patent 8,293,854 granted on 2012-10-23
US20120202954A1
Chemistry; metallurgy

Synthesis of chabazite-containing molecular sieves and their use in the conversion of oxygenates to olefins

#4363 ✅ Patent 10,711,077 granted on 2020-07-14
US20120202955A1
Chemistry; metallurgy

Ziegler-natta catalyst composition with controlled morphology

#4364 ✅ Patent 8,546,595 granted on 2013-10-01
US20120202956A1
Chemistry; metallurgy

Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization

#4365 ✅ Patent 8,895,775 granted on 2014-11-25
US20120202957A1
Chemistry; metallurgy

Method for preparing conjugated diene phosphonate compounds

#4366 ✅ Patent 9,120,917 granted on 2015-09-01
US20120202958A1
Chemistry; metallurgy

N-substituted acrylamides, preparation method and use thereof

#4367
US20120202959A1
Chemistry; metallurgy

Process for Producing Water-Absorbing Polymer Particles

#4368 ✅ Patent 8,372,934 granted on 2013-02-12
US20120202960A1
Chemistry; metallurgy

Method for producing organopolysiloxanes

#4369 ✅ Patent 8,552,217 granted on 2013-10-08
US20120202961A1
Chemistry; metallurgy

Isocyanate manufacture

#4370 ✅ Patent 8,604,156 granted on 2013-12-10
US20120202962A1
Chemistry; metallurgy

Device and method for producing polybutylene succinate

#4371 ✅ Patent 8,445,625 granted on 2013-05-21
US20120202963A1
Chemistry; metallurgy

Polyether and its production process

#4372
US20120202964A1
Chemistry; metallurgy

COPOLYESTER AND PREPARATION METHOD AND USE THEREOF

#4373 ✅ Patent 8,236,921 granted on 2012-08-07
US20120202965A1
Chemistry; metallurgy

Integrated co-production of dicarboxylic acids

#4374
US20120202966A1
Chemistry; metallurgy

METHOD FOR PRODUCING POLYESTERS AND CO-POLYESTERS FROM LACTONES

#4375 ✅ Patent 8,389,665 granted on 2013-03-05
US20120202967A1
Chemistry; metallurgy

Method for preparing terpolymer of poly (biphenyl sulfone ether) and poly (ether sulfone)

#4376 ✅ Patent 9,272,983 granted on 2016-03-01
US20120202968A1
Chemistry; metallurgy

2-amino-3-methyl-hex-5-enoic acid and its use in the production of peptides including bacitracins

#4377 ✅ Patent 8,916,521 granted on 2014-12-23
US20120202969A1
Chemistry; metallurgy

Method for insulin resistance improving and a method for prevention or treatment of diabetes

#4378 ✅ Patent 9,175,357 granted on 2015-11-03
US20120202970A1
Physics

Fragment ligated inhibitors selective for the polo box domain of PLK1

#4379
US20120202971A1
Chemistry; metallurgy

LIGHT ACTIVATED ASSOCIATION OF SPLIT GFP

#4380
US20120202972A1
Chemistry; metallurgy

Motor proteins propelling nano-scale devices and systems

#4381 ✅ Patent 9,255,138 granted on 2016-02-09
US20120202973A1
Chemistry; metallurgy

Method for extracting recombinant human serum albumin from transgenic rice grain

#4382
US20120202974A1
Chemistry; metallurgy

PROCESS FOR THE PURIFICATION OF FC-CONTAINING PROTEINS

#4383 ✅ Patent 8,895,707 granted on 2014-11-25
US20120202975A1
Chemistry; metallurgy

Elution of proteins from hydroxyapatite resins without resin deterioration

#4384
US20120202976A1
Performing operations; transporting

SEPARATION MATRICES

#4385
US20120202977A1
Chemistry; metallurgy

SINGLE DOMAIN ANTIBODIES DIRECTED AGAINST TUMOR NECROSIS FACTOR-ALPHA AND USES THEREFOR

#4386 ✅ Patent 8,357,301 granted on 2013-01-22
US20120202978A1
Physics

Chromatography equipment characterization

#4387 ✅ Patent 9,175,027 granted on 2015-11-03
US20120202979A1
Chemistry; metallurgy

Polymer-carbohydrate-lipid conjugates

#4388 ✅ Patent 8,916,526 granted on 2014-12-23
US20120202980A1
Chemistry; metallurgy

Flavanone derivative

#4389 ✅ Patent 9,056,886 granted on 2015-06-16
US20120202981A1
Chemistry; metallurgy

Guanosine-rich modified oligonucleotides and antiproliferative activity thereof

#4390 ✅ Patent 8,450,473 granted on 2013-05-28
US20120202982A1
Human necessities

Compositions and methods for therapy of macular degeneration

#4391 ✅ Patent 8,461,313 granted on 2013-06-11
US20120202983A1
Human necessities

Conjugates and compositions for cellular delivery

#4392 ✅ Patent 9,156,918 granted on 2015-10-13
US20120202984A1
Chemistry; metallurgy

Treatment of cellulose esters

#4393
US20120202985A1
Chemistry; metallurgy

Hyper IgE Animal Model with Enhanced Immunoglobulin Heavy Chain Class Switching to C-epsilon

#4394 ✅ Patent 8,440,818 granted on 2013-05-14
US20120202986A1
Performing operations; transporting

System and method for gas reaction

#4395 ✅ Patent 8,846,904 granted on 2014-09-30
US20120202987A1
Chemistry; metallurgy

Water-soluble porphyrin and process for production thereof

#4396 ✅ Patent 8,754,207 granted on 2014-06-17
US20120202988A1
Chemistry; metallurgy

Process for the preparation of rapamycin derivatives

#4397
US20120202989A1
Chemistry; metallurgy

PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMORPHIC FORMS ALPHA, BETA, AND GAMMA OF RIFAXIMIN

#4398 ✅ Patent 9,012,630 granted on 2015-04-21
US20120202990A1
Chemistry; metallurgy

Method for producing bridged manganese complexes of triazacyclononane

#4399 ✅ Patent 8,653,257 granted on 2014-02-18
US20120202991A1
Chemistry; metallurgy

Dibenzothiazepine derivatives and uses thereof—424

#4400 ✅ Patent 8,921,380 granted on 2014-12-30
US20120202992A1
Chemistry; metallurgy

Pyrazolo[1,5-a] pyrimidine compounds as CB1 receptor antagonist

#4401 ✅ Patent 8,476,428 granted on 2013-07-02
US20120202993A1
Chemistry; metallurgy

Method of preparing cyclic carbonates, cyclic carbamates, cyclic ureas, cyclic thiocarbonates, cyclic thiocarbamates, and cyclic dithiocarbonates

#4402 ✅ Patent 8,871,964 granted on 2014-10-28
US20120202994A1
Performing operations; transporting

Method for carrying out chemical reactions with the aid of an inductively heated heating medium

#4403 ✅ Patent 8,907,084 granted on 2014-12-09
US20120202995A1
Chemistry; metallurgy

Process for the preparation of 2-(2-aminoethoxy) ethanol (2AEE) and morpholine with 2AEE: morpholine >3

#4404 ✅ Patent 8,258,293 granted on 2012-09-04
US20120202996A1
Chemistry; metallurgy

Tetrahydroquinoline derivatives

#4405 ✅ Patent 8,785,636 granted on 2014-07-22
US20120202997A1
Chemistry; metallurgy

Substituted indoloacridines for organic electroluminescent devices

#4406 ✅ Patent 8,569,491 granted on 2013-10-29
US20120202998A1
Chemistry; metallurgy

Method for preparing entecavir and intermediate used therein

#4407 ✅ Patent 8,470,837 granted on 2013-06-25
US20120202999A1
Chemistry; metallurgy

MAPK/ERK kinase inhibitors

#4408
US20120203000A1
Chemistry; metallurgy

POLYMORPHIC FORMS ALPHA, BETA AND GAMMA OF RIFAXIMIN

#4409 ✅ Patent 8,507,590 granted on 2013-08-13
US20120203001A1
Chemistry; metallurgy

Fluorescent brighteners, methods of preparation thereof, fluorescent brightener compositions, and methods of preparation and uses thereof

#4410 ✅ Patent 8,633,317 granted on 2014-01-21
US20120203002A1
Chemistry; metallurgy

Crystalline salts of thieno[3,2-c]pyridine kinase inhibitors with improved cpy safety profile

#4411
US20120203003A1
Chemistry; metallurgy

Continuous Flow Process For The Preparation Of Sulphoxide Compounds

#4412
US20120203004A1
Chemistry; metallurgy

PROCESS FOR THE SYNTHESIS OF ALKYL/ARALKYL (2S)-2-(TERT-BUTOXYCARBONYL)-AMINO-2-[-8-AZABICYCLO[3.2.1]OCT-3-YL]-EXO-ACETATE AND ANALOGS THEREOF: KEY INTERMEDIATES FOR THE PREPARATION OF DPPIV INHIBITORS

#4413 ✅ Patent 9,101,620 granted on 2015-08-11
US20120203005A1
Human necessities

Polymorph of 3-(substituteddihydroisoindolinone-2-yl)-2,6-dioxopiperidine, and pharmaceutical compositions thereof

#4414 ✅ Patent 8,461,342 granted on 2013-06-11
US20120203006A1
Chemistry; metallurgy

Processes for producing cycloalkylcarboxamido-pyridine benzoic acids

#4415 ✅ Patent 8,436,030 granted on 2013-05-07
US20120203007A1
Chemistry; metallurgy

Polymorphic forms of deferasirox (ICL670A)

#4416 ✅ Patent 8,697,886 granted on 2014-04-15
US20120203008A1
Chemistry; metallurgy

Di(aminoguanidium) 4,4′,5,5′-tetranitro-2,2′-biimidazole, and preparation method thereof

#4417 ✅ Patent 8,558,006 granted on 2013-10-15
US20120203009A1
Chemistry; metallurgy

Processes relating to the alkylation of pyrazoles

#4418 ✅ Patent 9,650,565 granted on 2017-05-16
US20120203010A1
Chemistry; metallurgy

Carbazole compound and use thereof

#4419 ✅ Patent 8,680,295 granted on 2014-03-25
US20120203011A1
Chemistry; metallurgy

Process for producing bis(thietanylthio)dithiastannolane

#4420 ✅ Patent 8,609,869 granted on 2013-12-17
US20120203012A1
Chemistry; metallurgy

Heteroaromatic-containing compound, optical material and optical element

#4421 ✅ Patent 8,957,260 granted on 2015-02-17
US20120203013A1
Chemistry; metallurgy

Process for the oxidation of mesitol

#4422 ✅ Patent 8,637,702 granted on 2014-01-28
US20120203014A1
Human necessities

Derivatives of N-hydroxybenzamide for treating HIV infections

#4423 ✅ Patent 8,895,763 granted on 2014-11-25
US20120203015A1
Chemistry; metallurgy

Method and device for producing alkylene oxides and alkylene glycols

#4424 ✅ Patent 9,961,846 granted on 2018-05-08
US20120203016A1
Human necessities

High oleic imidazolinone resistance sunflower

#4425 ✅ Patent 8,604,228 granted on 2013-12-10
US20120203017A1
Chemistry; metallurgy

Method for purifying fatty acid alkyl ester greatly loaded with saponification products

#4426 ✅ Patent 9,249,436 granted on 2016-02-02
US20120203018A1
Chemistry; metallurgy

Tailored oils produced from recombinant oleaginous microorganisms

#4427 ✅ Patent 8,710,254 granted on 2014-04-29
US20120203019A1
Chemistry; metallurgy

Method for producing organo-oligo silsesquioxanes

#4428 ✅ Patent 8,691,994 granted on 2014-04-08
US20120203020A1
Chemistry; metallurgy

Multi-component polymerization inhibitors for ethylenically unsaturated monomers

#4429 ✅ Patent 8,329,936 granted on 2012-12-11
US20120203021A1
Chemistry; metallurgy

Method for producing cyanoacrylate esters in the presence of transition metal catalysts

#4430 ✅ Patent 8,871,965 granted on 2014-10-28
US20120203022A1
Chemistry; metallurgy

Method for producing urethanes

#4431
US20120203023A1
Chemistry; metallurgy

Process For Preparing A Phenylalanine Derivative

#4432 ✅ Patent 8,617,789 granted on 2013-12-31
US20120203024A1
Chemistry; metallurgy

Photoacid generator, method for producing the same, and resist composition comprising the same

#4433 ✅ Patent 8,536,367 granted on 2013-09-17
US20120203025A1
Chemistry; metallurgy

Vinyl ester production from acetylene and carboxylic acid utilizing homogeneous catalyst

#4434
US20120203026A1
Chemistry; metallurgy

METHOD FOR MANUFACTURING TRICYCLODECANE MONO-METHANOL MONOCARBOXYLIC ACID DERIVATIVE

#4435 ✅ Patent 8,487,126 granted on 2013-07-16
US20120203027A1
Chemistry; metallurgy

Process for preparation of diethylenetriaminepentaacetic acid derivative, and diethylenetriaminepentaacetic acid derivative

#4436
US20120203028A1
Chemistry; metallurgy

PROCESS FOR THE PREPARATION OF PURE ACRYLATE ESTERS

#4437 ✅ Patent 9,353,042 granted on 2016-05-31
US20120203029A1
Chemistry; metallurgy

Production of acetates from acetic acid and alcohols

#4438 ✅ Patent 8,889,901 granted on 2014-11-18
US20120203030A1
Chemistry; metallurgy

Photoacid generator, method for producing the same, and resist composition comprising the same

#4439
US20120203031A1
Chemistry; metallurgy

Sustainable chemical process for reduction of nitro compounds (R-NO2) or nitroso compounds (R-NO) containing sulphonic or carboxylic group into corresponding amino compounds (R-NH2) with inherent recycle of all acidic streams generated in synthesis

#4440
US20120203032A1
Chemistry; metallurgy

PROCESS FOR PRODUCING AND PURIFYING A CONCENTRATED LACTIC SALT

#4441 ✅ Patent 8,642,811 granted on 2014-02-04
US20120203033A1
Chemistry; metallurgy

Preparation of primary diamines having a linear main chain for polyamide syntheses

#4442 ✅ Patent 8,362,302 granted on 2013-01-29
US20120203034A1
Chemistry; metallurgy

Composite catalyst and using the same for making isopropyl alcohol

#4443
US20120203035A1
Chemistry; metallurgy

HYDROCARBON SELECTIVE OXIDATION WITH HETEROGENOUS GOLD CATALYSTS

#4444 ✅ Patent 8,324,436 granted on 2012-12-04
US20120203036A9
Chemistry; metallurgy

Gas phase synthesis of 2,3,3,3-tetrafluoro-1-propene from 2-chloro-3,3,3-trifluoro-1-propene

#4445 ✅ Patent 9,012,703 granted on 2015-04-21
US20120203037A1
Chemistry; metallurgy

Process for purifying (hydro) fluoroalkenes

#4446 ✅ Patent 9,207,686 granted on 2015-12-08
US20120203038A1
Chemistry; metallurgy

Versatile systems for continuous in-line blending of butane and petroleum

#4447 ✅ Patent 8,663,458 granted on 2014-03-04
US20120203039A1
Chemistry; metallurgy

Process to hydrodesulfurize pyrolysis gasoline

#4448
US20120203040A1
Chemistry; metallurgy

Process for the Production of Paraffinic Hydrocarbons

#4449 ✅ Patent 8,354,566 granted on 2013-01-15
US20120203041A1
Chemistry; metallurgy

Lubricating oil additive and lubricating oil composition containing same

#4450 ✅ Patent 9,169,442 granted on 2015-10-27
US20120203042A1
Chemistry; metallurgy

Systems and processes for catalytic pyrolysis of biomass and hydrocarbonaceous materials for production of aromatics with optional olefin recycle, and catalysts having selected particle size for catalytic pyrolysis

#4451 ✅ Patent 9,120,712 granted on 2015-09-01
US20120203043A1
Chemistry; metallurgy

Process for improving the energy density of feedstocks using formate salts

#4452 ✅ Patent 8,912,376 granted on 2014-12-16
US20120203044A1
Chemistry; metallurgy

Process for upgrading a pyrolysis oil, in particular in a refinery

#4453 ✅ Patent 9,486,796 granted on 2016-11-08
US20120203045A1
Performing operations; transporting

Process for producing an si-bonded fluidized-bed catalyst

#4454 ✅ Patent 10,112,187 granted on 2018-10-30
US20120203046A1
Performing operations; transporting

High strength SAPO-34 microsphere catalyst, method for preparing same, and method for preparing light olefins using same

#4455 ✅ Patent 8,829,260 granted on 2014-09-09
US20120203047A1
Performing operations; transporting

Process and catalyst for cracking of ethers and alcohols

#4456 ✅ Patent 8,647,999 granted on 2014-02-11
US20120203048A1
Performing operations; transporting

Method for regenerating a catalyst containing a CHA zeolite

#4457
US20120203049A1
Mechanical engineering

HEAT EXCHANGE DEVICE AND A METHOD OF MANUFACTURING THE SAME

#4458 ✅ Patent 9,700,621 granted on 2017-07-11
US20120203050A1
Human necessities

Metallic nanoparticles, preparation and uses thereof

#4459 ✅ Patent 8,710,099 granted on 2014-04-29
US20120203051A1
Human necessities

Treatment of cancer using the sodium salt of a benzoic acid derivative

#4460
US20120203052A1
Human necessities

THERAPEUTIC REGIMEN FOR TREATING CANCER

#4461 ✅ Patent 9,044,602 granted on 2015-06-02
US20120203053A1
Human necessities

Sequential optimizations for treatment planning

#4462 ✅ Patent 9,421,392 granted on 2016-08-23
US20120203054A1
Human necessities

Method and apparatus for determining the proximity of a TMS coil to a subject's head

#4463 ✅ Patent 9,226,872 granted on 2016-01-05
US20120203055A1
Human necessities

Apparatus for treating and/or preventing diseases and functional disorders of external genital organs

#4464 ✅ Patent 8,992,406 granted on 2015-03-31
US20120203056A1
Human necessities

Anatomic fit of a percutaneous VAD for right heart support

#4465 ✅ Patent 8,535,365 granted on 2013-09-17
US20120203057A1
Human necessities

Moxa burning bowl

#4466
US20120203058A1
Physics

MOTION ACTIVATED ELECTRONIC THERAPEUTIC CUE DEVICE AND METHOD

#4467 ✅ Patent 10,028,813 granted on 2018-07-24
US20120203059A1
Human necessities

Coated pelvic implant device and method

#4468 ✅ Patent 9,017,243 granted on 2015-04-28
US20120203060A1
Human necessities

Minimally invasive implant and method

#4469 ✅ Patent 9,877,860 granted on 2018-01-30
US20120203061A1
Human necessities

Bariatric device and method for weight loss

#4470
US20120203062A1
Human necessities

DEVICE FOR SHAPING A BODY PART

#4471 ✅ Patent 9,072,538 granted on 2015-07-07
US20120203063A1
Human necessities

Treatment tool for endoscope

#4472 ✅ Patent 8,888,787 granted on 2014-11-18
US20120203064A1
Human necessities

Percutaneous renal access system

#4473 ✅ Patent 9,757,021 granted on 2017-09-12
US20120203065A1
Human necessities

Global and semi-global registration for image-based bronchoscopy guidance

#4474 ✅ Patent 8,915,836 granted on 2014-12-23
US20120203066A1
Human necessities

Endoscope, guide unit, guide wire, medical-device guiding system, and medical-device guiding method

#4475
US20120203067A1
Human necessities

METHOD AND DEVICE FOR DETERMINING THE LOCATION OF AN ENDOSCOPE

#4476
US20120203068A1
Human necessities

CAPSULE GUIDING SYSTEM

#4477
US20120203069A1
Human necessities

SURGICAL SHIELD FOR SOFT TISSUE PROTECTION

#4478 ✅ Patent 9,049,989 granted on 2015-06-09
US20120203070A1
Human necessities

Methods and devices to decrease tissue trauma during surgery

#4479 ✅ Patent 9,370,379 granted on 2016-06-21
US20120203071A1
Human necessities

Endoscopic soft tissue working space creation

#4480
US20120203072A1
Human necessities

Apical Instrument Port

#4481 ✅ Patent 8,652,105 granted on 2014-02-18
US20120203073A1
Human necessities

Endoluminal access device

#4482
US20120203074A1
Human necessities

SURGICAL PORTAL APPARATUS WITH ARMATURE ASSEMBLY

#4483
US20120203075A1
Human necessities

White coherent laser light launched into nano fibers for surgical illumination

#4484
US20120203076A1
Human necessities

Portable Physiological Data Monitoring Device

#4485
US20120203077A1
Human necessities

Wearable Vital Signs Monitor

#4486 ✅ Patent 9,195,799 granted on 2015-11-24
US20120203078A1
Physics

Wireless patient monitoring system

#4487 ✅ Patent 9,326,720 granted on 2016-05-03
US20120203079A1
Human necessities

Wireless, implantable electro-encephalography system

#4488
US20120203080A1
Human necessities

PHOTOPLETHYSMOGRAPHY APPARATUS

#4489
US20120203081A1
Physics

PHYSIOLOGICAL AND ENVIRONMENTAL MONITORING APPARATUS AND SYSTEMS

#4490 ✅ Patent 10,033,106 granted on 2018-07-24
US20120203082A1
Electricity

Transdermal antenna

#4491 ✅ Patent 8,647,357 granted on 2014-02-11
US20120203083A1
Human necessities

Lancet device with flexible cover

#4492
US20120203084A1
Human necessities

POSITIONING SYSTEM, APPARATUS, AND METHOD FOR WIRELESS MONITORING OF ESOPHAGEAL pH VALUE

#4493
US20120203085A1
Physics

NON-INVASIVE SYSTEM AND METHOD FOR MEASURING AN ANALYTE IN THE BODY

#4494 ✅ Patent 8,989,848 granted on 2015-03-24
US20120203086A1
Human necessities

Apparatus and method for non-invasively detecting diseases that affect structural properties in biological tissues

#4495 ✅ Patent 9,615,781 granted on 2017-04-11
US20120203087A1
Human necessities

Systems and methods for monitoring depth of consciousness

#4496 ✅ Patent 9,138,146 granted on 2015-09-22
US20120203088A1
Human necessities

Biological optical measurement instrument and reference image display method

#4497 ✅ Patent 8,597,190 granted on 2013-12-03
US20120203089A1
Human necessities

Monitoring systems and methods with fast initialization

#4498 ✅ Patent 10,016,607 granted on 2018-07-10
US20120203090A1
Human necessities

Systems and methods for tracking stroke volume using hybrid impedance configurations employing a multi-pole implantable cardiac lead

#4499 ✅ Patent 9,345,411 granted on 2016-05-24
US20120203091A1
Human necessities

Devices and methods for monitoring cerebral hemodynamic conditions

#4500 ✅ Patent 10,098,584 granted on 2018-10-16
US20120203092A1
Human necessities

Patient health improvement monitor