Assignee profile:

LES LABORATOIRES SERVIER

City:

SURESNES CEDEX

Country:

France

Published Applications:

136

Last publication date:

2025-08-28

Patent Grants:

103

Last grant date:

2026-03-17

Top Inventors for applications by LES LABORATOIRES SERVIER

These are the the leading inventors for applications assigned to LES LABORATOIRES SERVIER:

Recent patent applications by LES LABORATOIRES SERVIER

LES LABORATOIRES SERVIER based in SURESNES CEDEX, FR has been assigned the rights to these inventions. The list includes both Pending Applications and Patent Grants:

#1 | 2025-08-28
US20250270317A1
Chemistry; metallurgy

CANCER THERAPY TARGETING NKG2A

#2 | 2025-07-03
US20250215091A1
Chemistry; metallurgy

Anti-GAL3 Antibodies and Compositions

#3 | 2025-06-05
US20250179195A1
Chemistry; metallurgy

ANTI-FLT3 ANTIBODIES AND COMPOSITIONS

#4 | 2025-06-05
US20250179063A2
Chemistry; metallurgy

SELECTIVE BCL-XL PROTAC COMPOUNDS AND METHODS OF USE

#5 | 2024-11-14
US20240376094A2
Chemistry; metallurgy

SELECTIVE BCL-XL PROTAC COMPOUNDS AND METHODS OF USE

#6 | 2024-09-05
US20240294638A1
Chemistry; metallurgy

ANTI-NKG2A ANTIBODIES AND COMPOSITIONS

#7 | 2024-08-15
US20240270848A1
Chemistry; metallurgy

COMBINATION THERAPIES TARGETING PD-1, TIM-3, AND LAG-3

#8 | 2023-07-20
US20230227573A1
Chemistry; metallurgy

ANTI-CD73 ANTIBODIES AND COMPOSITIONS

#9 | 2023-04-06 ✅ Patent 12,577,302 granted on 2026-03-17
US20230105714A1
Chemistry; metallurgy

ANTI-TIM-3 ANTIBODIES AND COMPOSITIONS

#10 | 2023-03-30 ✅ Patent 12,643,912 granted on 2026-06-02
US20230097678A1
Human necessities

NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

#11 | 2022-09-15 ✅ Patent 12,649,733 granted on 2026-06-09
US20220289734A1
Chemistry; metallurgy

3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS

#12 | 2022-07-07
US20220211718A1
Human necessities

BCL-2 INHIBITORS FOR USE IN THE TREATMENT OF A BCL-2 MEDIATED CANCER CARRYING THE GLY101VAL MUTATION

#13 | 2022-06-30
US20220203260A1
Performing operations; transporting

CONTAINMENT DEVICE FOR A ROTARY EVAPORATOR

#14 | 2019-08-08
US20190240225A1
Human necessities

COMBINATION OF A BCL-2 INHIBITOR AND A MCL-1 INHIBITOR, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF

#15 | 2016-06-16 ✅ Patent 9,663,451 granted on 2017-05-30
US20160168077A1
Chemistry; metallurgy

Forms of co-crystals of agomelatine and p toluenesulphonic acid, a process for their preparation and pharmaceutical compositions containing them

#16 | 2015-02-19 ✅ Patent 9,120,791 granted on 2015-09-01
US20150051189A1
Chemistry; metallurgy

Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them

#17 | 2015-01-29 ✅ Patent 9,108,983 granted on 2015-08-18
US20150031673A1
Chemistry; metallurgy

Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them

#18 | 2015-01-29 ✅ Patent 9,115,159 granted on 2015-08-25
US20150031648A1
Chemistry; metallurgy

Phosphate compounds, a process for their preparation and pharmaceutical compositions containing them

#19 | 2014-10-14 ✅ Patent 8,859,763 granted on 2014-10-14
US14277151
Chemistry; metallurgy

Process for the synthesis of 3,4-dimethoxybicyclo[4.2.0]OCTA-1,3,5-triene-7-carbonitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#20 | 2014-10-02 ✅ Patent 8,927,708 granted on 2015-01-06
US20140296512A1
Chemistry; metallurgy

Process for the synthesis of 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one compounds, and application in the synthesis of ivabradine

#21 | 2014-09-04 ✅ Patent 9,115,108 granted on 2015-08-25
US20140249215A1
Chemistry; metallurgy

Salt of abexinostat, associated crystalline form, a process for their preparation and pharmaceutical compositions containing them

#22 | 2014-08-28 ✅ Patent 9,476,071 granted on 2016-10-25
US20140242644A1
Chemistry; metallurgy

Process for the enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]OCTA-1,3,5-triene-7-carboxylic acid and application in the synthesis of ivabradine and salts thereof

#23 | 2014-08-07
US20140221449A1
Human necessities

DIVIDABLE GALENICAL FORM ALLOWING MODIFIED RELEASE OF THE ACTIVE INGREDIENT

#24 | 2014-06-12 ✅ Patent 8,779,123 granted on 2014-07-15
US20140163220A1
Chemistry; metallurgy

Process for the synthesis of 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#25 | 2014-06-05
US20140155453A1
Chemistry; metallurgy

SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-{3[CIS-HEXAHYDROCYCLOPENT A[CjPYRROL-2( 1 H)-YLjPROPOXYj BENZAMI DE HYDROCHLORI DE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

#26 | 2014-05-08 ✅ Patent 8,779,122 granted on 2014-07-15
US20140128598A1
Chemistry; metallurgy

Process for the synthesis of (2E)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#27 | 2014-05-01 ✅ Patent 9,573,914 granted on 2017-02-21
US20140121368A1
Chemistry; metallurgy

Process for preparing benzothiazepines from gamma-aminoalkylbenzenes

#28 | 2014-04-17 ✅ Patent 8,779,121 granted on 2014-07-15
US20140107334A1
Chemistry; metallurgy

Process for the synthesis of 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#29 | 2014-04-10 ✅ Patent 8,952,179 granted on 2015-02-10
US20140100374A1
Chemistry; metallurgy

Synthesis process, and crystalline form of 4-{3-[-hexahydrocyclopenta[]pyrrol-2(1)-yl]propoxy} benzamide hydrochloride and pharmaceutical compositions containing it

#30 | 2014-03-27 ✅ Patent 8,853,198 granted on 2014-10-07
US20140088171A1
Chemistry; metallurgy

Agents for treating disorders involving modulation of ryanodine receptors

#31 | 2014-01-23 ✅ Patent 9,045,788 granted on 2015-06-02
US20140024088A1
Chemistry; metallurgy

Process for the enzymatic synthesis of (7S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl) N-methyl methanamine, and application in the synthesis of ivabradine and salts thereof

#32 | 2014-01-09 ✅ Patent 9,527,803 granted on 2016-12-27
US20140011883A1
Chemistry; metallurgy

Crystal form VII of agomelatine, preparation method and use thereof and pharmaceutical composition containing same

#33 | 2013-12-12 ✅ Patent 8,653,073 granted on 2014-02-18
US20130331380A1
Chemistry; metallurgy

Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them

#34 | 2013-10-31 ✅ Patent 8,871,975 granted on 2014-10-28
US20130289308A1
Chemistry; metallurgy

Process for the synthesis of agomelatine

#35 | 2013-10-31 ✅ Patent 8,853,449 granted on 2014-10-07
US20130289307A1
Chemistry; metallurgy

Process for the synthesis of agomelatine

#36 | 2013-10-24
US20130281512A1
Chemistry; metallurgy

AGENTS FOR TREATING DISORDERS INVOLVING MODULATION OF RYANODINE RECEPTORS

#37 | 2013-10-10 ✅ Patent 8,779,199 granted on 2014-07-15
US20130267738A1
Chemistry; metallurgy

Agomelatine intermediates and preparation method thereof

#38 | 2013-10-03 ✅ Patent 8,835,627 granted on 2014-09-16
US20130261298A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#39 | 2013-08-15 ✅ Patent 8,778,930 granted on 2014-07-15
US20130211070A1
Chemistry; metallurgy

Process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile and application in the synthesis of ivabradine

#40 | 2013-08-15 ✅ Patent 9,506,095 granted on 2016-11-29
US20130210091A1
Chemistry; metallurgy

Process for the enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or esters thereof, and application in the synthesis of ivabradine and salts thereof

#41 | 2013-08-08 ✅ Patent 8,927,758 granted on 2015-01-06
US20130204032A1
Chemistry; metallurgy

Process for the resolution of enantiomers of (3,4 dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile and application in the synthesis of ivabradine

#42 | 2013-08-08 ✅ Patent 10,117,838 granted on 2018-11-06
US20130202710A1
Human necessities

Pharmaceutical composition for the prolonged release of trimetazidine

#43 | 2013-07-11 ✅ Patent 8,865,915 granted on 2014-10-21
US20130178635A1
Chemistry; metallurgy

Process for the preparation of the L-arginine salt of perindopril

#44 | 2013-06-20 ✅ Patent 8,507,668 granted on 2013-08-13
US20130158257A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#45 | 2013-06-20 ✅ Patent 8,513,410 granted on 2013-08-20
US20130158256A1
Performing operations; transporting

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#46 | 2013-06-13 ✅ Patent 8,921,409 granted on 2014-12-30
US20130150421A1
Human necessities

Combination of 4-{3-[-hexahydrocyclopenta[]pyrrol-2(1)-yl]propoxy}benzamide and a NMDA receptor antagonist and pharmaceutical compositions containing the same

#47 | 2013-03-14 ✅ Patent 8,883,199 granted on 2014-11-11
US20130064880A1
Human necessities

Administration regime for N-hydroxy-4-{2-[3-(N,N-dimethylaminomethyl)benzofuran-2- ylcarbonylamino]ethoxy}benzamide

#48 | 2013-02-14
US20130041040A1
Human necessities

SOLID PHARMACEUTICAL COMPOSITION FOR BUCCAL ADMINISTRATION OF AGOMELATINE

#49 | 2013-01-10 ✅ Patent 8,729,132 granted on 2014-05-20
US20130012592A1
Chemistry; metallurgy

Agomelatine hydrobromide hydrate and preparation thereof

#50 | 2013-01-03 ✅ Patent 8,729,131 granted on 2014-05-20
US20130005820A1
Chemistry; metallurgy

Agomelatine hydrochloride hydrate and preparation thereof

#51 | 2012-12-27 ✅ Patent 8,436,206 granted on 2013-05-07
US20120330062A1
Chemistry; metallurgy

Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and application in the synthesis of agomelatine

#52 | 2012-12-13 ✅ Patent 8,710,101 granted on 2014-04-29
US20120316245A1
Chemistry; metallurgy

Co-crystals of agomelatine, a process for there preparation and pharmaceutical compositions containing them

#53 | 2012-12-13 ✅ Patent 8,664,408 granted on 2014-03-04
US20120316214A1
Human necessities

Synthesis process, and crystalline form of 4-{3-[-hexahydrocyclopenta[]pyrrol-2(1)-yl]proxy}benzamide hydrochloride and pharmaceutical compositions containing it

#54 | 2012-12-06
US20120309838A1
Human necessities

USE OF AGOMELATINE IN OBTAINING MEDICAMENTS INTENDED FOR THE TREATMENT OF OBSESSIVE-COMPULSIVE DISORDER (OCD)

#55 | 2012-11-08
US20120283245A1
Chemistry; metallurgy

AZABICYCLO[3.1.0]HEX-2-YL COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

#56 | 2012-11-08 ✅ Patent 8,940,785 granted on 2015-01-27
US20120283244A1
Human necessities

Association between 4-{3-[-hexahydrocyclopenta[]pyrrol-2(1)-yl]propoxy}benzamide and an acetylcholinesterase inhibitor, and pharmaceutical compositions containing it

#57 | 2012-09-27
US20120245363A1
Chemistry; metallurgy

PROCESS FOR THE SYNTHESIS OF AGOMELATINE

#58 | 2012-09-13 ✅ Patent 8,778,932 granted on 2014-07-15
US20120232065A1
Chemistry; metallurgy

Dihydro-oxazolobenzodiazepinone compounds, a process for there preparation and pharmaceutical compositions containing them

#59 | 2012-08-16 ✅ Patent 8,476,426 granted on 2013-07-02
US20120208996A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#60 | 2012-08-16 ✅ Patent 8,404,742 granted on 2013-03-26
US20120208777A1
Chemistry; metallurgy

Diosmetin compounds, a process for their preparation and pharmaceutical compositions containing them

#61 | 2012-08-02
US20120196850A1
Human necessities

ASSOCIATION OF A SINUS NODE If CURRENT INHIBITOR AND AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

#62 | 2012-07-05
US20120172589A1
Chemistry; metallurgy

PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID

#63 | 2012-05-10 ✅ Patent 8,288,581 granted on 2012-10-16
US20120116112A1
Chemistry; metallurgy

Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#64 | 2012-03-29
US20120076856A1
Human necessities

ORODISPERSIBLE PHARMACEUTICAL COMPOSITION OF PERINDOPRIL

#65 | 2012-03-22 ✅ Patent 8,569,285 granted on 2013-10-29
US20120071462A1
Chemistry; metallurgy

Dihydrobenzoxathiazepine compounds, a process for their preparation and pharmaceutical compositions containing them

#66 | 2012-02-23 ✅ Patent 8,541,412 granted on 2013-09-24
US20120046287A1
Chemistry; metallurgy

Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them

#67 | 2012-02-02
US20120029210A1
Chemistry; metallurgy

Process for the synthesis of strontium ranelate and its hydrates

#68 | 2011-12-15
US20110306598A1
Human necessities

Use of the association of a sinus node if current inhibitor and an angiotensin-converting enzyme inhibitor in the treatment of heart failure

#69 | 2011-12-01 ✅ Patent 8,415,468 granted on 2013-04-09
US20110294999A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#70 | 2011-11-24
US20110288072A1
Human necessities

Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction

#71 | 2011-09-29
US20110237644A1
Physics

UBIQUITIN SPECIFIC PROTEASES RESPONSIBLE FOR MCL-1 STABILITY AND USES THEREOF

#72 | 2011-09-22
US20110230466A1
Human necessities

Association of a sinus node if current inhibitor and calcium inhibitor and pharmaceutical compositions containing it

#73 | 2011-08-18 ✅ Patent 8,278,440 granted on 2012-10-02
US20110201805A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#74 | 2011-06-30 ✅ Patent 8,440,790 granted on 2013-05-14
US20110159598A1
Chemistry; metallurgy

Crystal structure of the CCZ-LZ domain of NEMO

#75 | 2011-06-09 ✅ Patent 8,008,337 granted on 2011-08-30
US20110136886A1
Chemistry; metallurgy

Azabicyclo[3.2.0] hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them

#76 | 2011-05-12
US20110112104A1
Chemistry; metallurgy

TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

#77 | 2011-05-05 ✅ Patent 8,663,660 granted on 2014-03-04
US20110105516A1
Human necessities

Polymerized micelles

#78 | 2011-02-10 ✅ Patent 8,133,889 granted on 2012-03-13
US20110034460A1
Chemistry; metallurgy

Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them

#79 | 2011-01-27 ✅ Patent 8,247,441 granted on 2012-08-21
US20110021490A1
Chemistry; metallurgy

Chromene compounds, a process for their preparation and pharmaceutical compositions containing them

#80 | 2010-12-30 ✅ Patent 8,309,341 granted on 2012-11-13
US20100330064A1
Chemistry; metallurgy

2-mercaptocyclopentanecarboxylic acid compounds, a process for their preparation and pharmaceutical compositions containing them

#81 | 2010-11-11 ✅ Patent 8,288,433 granted on 2012-10-16
US20100286225A1
Chemistry; metallurgy

Diazeniumdiolate compounds, a process for their preparation and pharmaceutical compositions containing them

#82 | 2010-10-21
US20100267799A1
Human necessities

Orodispersible pharmaceutical composition of perindopril

#83 | 2010-10-14
US20100260840A1
Human necessities

Orodispersible pharmaceutical composition of agomelatine

#84 | 2010-09-30 ✅ Patent 8,119,794 granted on 2012-02-21
US20100249398A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#85 | 2010-09-30 ✅ Patent 8,101,747 granted on 2012-01-24
US20100249397A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#86 | 2010-09-23 ✅ Patent 8,236,790 granted on 2012-08-07
US20100240635A1
Chemistry; metallurgy

Benzothiadiazepine compounds, a process for their preparation and pharmaceutical compositions containing them

#87 | 2010-08-12
US20100204276A1
Chemistry; metallurgy

INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

#88 | 2010-08-05
US20100197740A1
Chemistry; metallurgy

Method of Screening Compounds Having Anti-Amyloid Properties

#89 | 2010-07-01 ✅ Patent 7,947,852 granted on 2011-05-24
US20100168244A1
Chemistry; metallurgy

Naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them

#90 | 2010-06-24 ✅ Patent 8,097,720 granted on 2012-01-17
US20100160628A1
Chemistry; metallurgy

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

#91 | 2010-06-03 ✅ Patent 8,252,951 granted on 2012-08-28
US20100137628A1
Chemistry; metallurgy

Process for the synthesis of (methoxy-1-naphthyl) acetonitrile and application in the synthesis of agomelatine

#92 | 2010-06-03 ✅ Patent 8,173,644 granted on 2012-05-08
US20100137295A1
Chemistry; metallurgy

3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamatergic synaptic responses

#93 | 2010-05-13
US20100119459A1
Human necessities

Use of ivabradine as diagonstic agent in the method of coronary angiography by multislice computed tomography

#94 | 2010-03-25 ✅ Patent 7,910,625 granted on 2011-03-22
US20100076088A1
Chemistry; metallurgy

Crystalline form IV of agomelatine, a process for its preparation and pharmaceutical compositions containing it

#95 | 2010-03-11 ✅ Patent 7,939,566 granted on 2011-05-10
US20100063158A1
Chemistry; metallurgy

Crystalline form III of agomelatine, a process for its preparation and pharmaceutical compositions containing it

#96 | 2010-03-04 ✅ Patent 8,536,365 granted on 2013-09-17
US20100056778A1
Human necessities

Process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl) nitrile and application in the synthesis of ivabradine

#97 | 2010-02-18 ✅ Patent 7,879,842 granted on 2011-02-01
US20100041640A1
Chemistry; metallurgy

Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it

#98 | 2010-02-11 ✅ Patent 8,252,957 granted on 2012-08-28
US20100036165A1
Chemistry; metallurgy

Process for obtaining the crystalline form V of agomelatine

#99 | 2010-02-11 ✅ Patent 8,143,449 granted on 2012-03-27
US20100036163A1
Chemistry; metallurgy

Process for the synthesis of agomelatine

#100 | 2010-02-11 ✅ Patent 8,212,077 granted on 2012-07-03
US20100036162A1
Chemistry; metallurgy

Process for the synthesis of agomelatine

Also check out Les Laboratoires Servier's (Suresnes Cedex, France) applicant profile with 43 patent applications submitted.

AssigneeID:

1985