ClassID:

2172

A01K2207/12 - CPC Classification

Classification description:

Modified animals Animals modified by administration of exogenous cells

Recent Application in this class:
#1
20260146236
2026-05-28

HUMAN SEBACEOUS GLAND CARCINOMA CELL LINE AND US THEREOF

#2
20260144239
2026-05-28

Immune Cell-Engrafted Non-Human Animals and Non-Human Animal Models

#3
20260144238
2026-05-28

SKIN TISSUE

#4
20260132383
2026-05-14

COMPOSITIONS AND METHODS FOR DELIVERY OF IMMUNE CELLS TO TREAT UN-RESECTABLE OR NON-RESECTED TUMOR CELLS AND TUMOR RELAPSE

#5
20260108632
2026-04-23

METHOD FOR PRODUCING A SPONTANEOUS METASTASIS MODEL

#6
20260107929
2026-04-23

NON-HUMAN ANIMALS COMPRISING A MODIFIED TRANSFERRIN RECEPTOR LOCUS

#7
20260098278
2026-04-09

CELLS, TISSUES, ORGANS, AND ANIMALS HAVING ONE OR MORE MODIFIED GENES FOR ENHANCED XENOGRAFT SURVIVAL AND TOLERANCE

#8
20260090528
2026-04-02

ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATION

#9
20260083106
2026-03-26

HUMANIZED IMMUNODEFICIENT MOUSE MODELS

#10
20260076346
2026-03-19

IMMUNODEFICIENT NON-HUMAN ANIMALS FOR ASSESSING DRUG METABOLISM AND TOXICITY

#11
20260060222
2026-03-05

Genetically Modified Mice and Engraftment

#12
20260033467
2026-02-05

METHODS AND MODELS FOR ASSESSING EFFICACY OF IMMUNOTHERAPIES

#13
20260007123
2026-01-08

THYMOCYTE HUMANIZED ANIMALS, METHODS OF MAKING AND METHODS OF USE THEREOF

#14
20260007122
2026-01-08

AAVR KNOCKOUT MOUSE IN COMBINATION WITH HUMAN LIVER CHIMERISM AND METHODS OF USE AND PRODUCTION OF THE SAME

#15
20250388642
2025-12-25

COMPOSITIONS AND METHODS FOR IMPROVED NK CELL THERAPIES

#16
20250369955
2025-12-04

MOUSE MODELS OF CYTOKINE RELEASE SYNDROME

#17
20250346918
2025-11-13

CELLS, TISSUES, ORGANS, AND ANIMALS HAVING ONE OR MORE MODIFIED GENES FOR ENHANCED XENOGRAFT SURVIVAL AND TOLERANCE

#18
20250280805
2025-09-11

METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS

#19
20250255282
2025-08-14

VECTORS, GENETICALLY MODIFIED CELLS, AND GENETICALLY MODIFIED NON-HUMAN ANIMALS COMPRISING THE SAME

#20
20250212854
2025-07-03

IMMUNODEFICIENT FCGR1 KNOCKOUT MOUSE MODELS

#21
20250171740
2025-05-29

METHODS FOR GENERATING FUNCTIONAL HEMATOPOIETIC STEM CELLS

#22
20250164467
2025-05-22

HUMANIZED MOUSE MODELS FOR ASSESSING IMMUNE CELL THERAPY

#23
20250143272
2025-05-08

GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC NKP46

#24
20250127149
2025-04-24

MICRORNA INHIBITOR THERAPY IN SYSTEMIC LUPUS ERYTHEMATOSUS

#25
20250120372
2025-04-17

HUMANIZED MOUSE MODEL OF FIBROSIS

#26
20250113808
2025-04-10

BRAIN-METASTATIC LUNG CANCER CELL LINE AND USE OF NOGGIN AS MARKER FOR BRAIN METASTASIS OF LUNG CANCER

#27
20250092353
2025-03-20

COMMENSAL FUNGUS AND USES THEREOF

#28
20250075175
2025-03-06

EFFICIENT DERIVATION OF STABLE PLURIPOTENT BOVINE EMBRYONIC STEM CELLS

#29
20250072406
2025-03-06

Humanized M-CSF Mice

#30
20250072405
2025-03-06

Genetically Modified Non-Human Animals And Methods Of Use Thereof

#31
20250057888
2025-02-20

USE OF ALVEOLAR OR AIRWAY ORGANOIDS FOR THE TREATMENT OF LUNG DISEASES AND DISORDERS

#32
20250027048
2025-01-23

Genetically Modified Hepatocyte Populations

#33
20240389561
2024-11-28

Kit for breeding a TGEV infection resistant pig and use thereof

#34
20240376432
2024-11-14

METHOD FOR PREPARING PLURIPOTENT STEM CELL-DERIVED HEMATOPOIETIC STEM CELL AND METHOD FOR CONSTRUCTING HUMANIZED MOUSE MODEL BY USING HEMATOPOIETIC STEM CELL THUS PREPARED

#35
20240341291
2024-10-17

NON-HUMAN ANIMALS HAVING A HUMANIZED B-CELL ACTIVATING FACTOR GENE

#36
20240306616
2024-09-19

Non-Human Animals Expressing Humanized CD3 Complex

#37
20240301361
2024-09-12

Formation of Three-Dimensional Organ from Pluripotent Stem Cells

#38
20240269175
2024-08-15

COMPOSITIONS AND METHODS OF CELLULAR IMMUNOTHERAPY

#39
20240268361
2024-08-15

GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC TFR1

#40
20240254514
2024-08-01

ARTIFICIAL EXPRESSION CONSTRUCTS FOR MODULATING GENE EXPRESSION IN NEURONS WITHIN THE THALAMUS

#41
20240254451
2024-08-01

HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)

#42
20240138384
2024-05-02

NON-HUMAN ANIMALS HAVING A HUMANIZED CLUSTER OF DIFFERENTIATION 47 GENE

#43
20240122984
2024-04-18

COMPOSITIONS AND METHODS FOR DELIVERY OF IMMUNE CELLS TO TREAT UN-RESECTABLE OR NON-RESECTED TUMOR CELLS AND TUMOR RELAPSE

#44
20240114883
2024-04-11

Genetically modified non-human having humanized gamma and delta TCR variable genes

#45
20240108762
2024-04-04

METHOD FOR CULTURING 3-DIMENSIONAL LUNG CANCER ORGANOID AND METHOD FOR PREPARING PATIENT-DERIVED XENOGRAFT ANIMAL MODEL USING SAME

#46
20240108590
2024-04-04

MAINTENANCE OF PROGRAMMED CHRONIC LIVER INJURY OF FAH GENE-DEFICIENT ANIMALS AND APPLICATION THEREOF IN PREPARATION OF HETEROLOGOUS LIVER MODELS

#47
20240093193
2024-03-21

DEAD GUIDES FOR CRISPR TRANSCRIPTION FACTORS

#48
20240093145
2024-03-21

IN VITRO METHODS OF DIFFERENTIATING STEM CELLS INTO NEURONS AND NEURONS GENERATED USING THE SAME

#49
20240084322
2024-03-14

CELLS, TISSUES, ORGANS, AND ANIMALS HAVING ONE OR MORE MODIFIED GENES FOR ENHANCED XENOGRAFT SURVIVAL AND TOLERANCE

#50
20240076615
2024-03-07

MODELS AND METHODS FOR RAPID SCREENING OF THE EFFICACY OF IMMUNOREGULATING DRUGS

#51
20240075109
2024-03-07

TELOMERASE REVERSE TRANSCRIPTASE-BASED THERAPIES

#52
20240074414
2024-03-07

GENETICALLY MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO

#53
20240057571
2024-02-22

SIMULATION METHOD FOR CHRONIC ATROPHIC GASTRITIS (CAG) LESION AND IDENTIFICATION METHOD FOR MOUSE MODELING

#54
20240041011
2024-02-08

INFECTIOUS DISEASE MOUSE MODELS

#55
20240032513
2024-02-01

Materials for Tumor Inoculation in Murine Mouse Models and Uses Thereof

#56
20240011101
2024-01-11

METHOD OF DETERMINING RESISTANCE TO CHECKPOINT INHIBITOR THERAPIES

#57
20240000050
2024-01-04

APPLICATION OF PLURIPOTENT STEM CELLS HAVING MODIFIED DIFFERENTIAL POTENTIAL TO PRODUCING ANIMALS

#58
20230337642
2023-10-26

METHOD FOR PRODUCING AVATAR MOUSE AS ATOPIC DERMATITIS ANIMAL MODEL AND USE THEREOF

#59
20230303981
2023-09-28

BLADDER ORGANOID AND METHOD FOR PRODUCING SAME

#60
20230292721
2023-09-21

GENETICALLY MODIFIED NON-HUMAN ANIMALS AND METHODS OF USE THEREOF

#61
20230292718
2023-09-21

METHOD FOR CONSTRUCTING MODEL OF VITILIGO AND THE USE OF THE MODEL

#62
20230255186
2023-08-17

HUMANIZED MOUSE MODELS FOR SARS-COV-2 INFECTION

#63
20230227531
2023-07-20

GENETICALLY MODIFIED NON-HUMAN ANIMAL EXPRESSING A B2M/FCRN FUSION PROTEIN

#64
20230189773
2023-06-22

ENGINEERED CELLS, ANIMAL MODELS, AND USES THEREOF FOR MODELING LOW GRADE GLIOMA (LGG)

#65
20230183752
2023-06-15

COMPLEXES FOR GENE DELETION AND EDITING

#66
20230180725
2023-06-15

Production of Human Cells, Tissues, and Organs in a Growth Factor Receptor-Deficient Animal Host

#67
20230173110
2023-06-08

NON-HUMAN MAMMAL MODEL OF HUMAN DEGENERATIVE DISORDER, USES THEREOF, AND METHOD OF TREATING HUMAN DEGENERATIVE DISORDER

#68
20230146422
2023-05-11

ANIMAL MODEL FOR STUDYING CANCER IMMUNOTHERAPY

#69
20230126434
2023-04-27

OPTIMIZED CRISPR/CAS9 SYSTEMS AND METHODS FOR GENE EDITING IN STEM CELLS

#70
20230112372
2023-04-13

PRIMATIZED RODENT

#71
20230085803
2023-03-23

METHOD FOR SEARCHING AND SCREENING FOR TARGET OF ANTI-CANCER AGENT USING NON-HUMAN ANIMAL MODEL HAVING NOG ESTABLISHED CANCER CELL LINE TRANSPLANTED THEREIN

#72
20230073534
2023-03-09

MODULATING TLR/NF-KB AND P53 SIGNALING PATHWAYS TO ENHANCE INTERSPECIES CHIMERISM BETWEEN EVOLUTIONARYILY DISTANT SPECIES

#73
20230058049
2023-02-23

GENETICALLY MODIFIED IMMUNODEFICIENT NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC SIRPa/CD47

#74
20230031499
2023-02-02

TARGETING GLIOBLASTOMA STEM CELLS THROUGH THE TLX-TET3 AXIS

#75
20230002727
2023-01-05

THYMUS ORGANOIDS BIOENGINEERED FROM HUMAN PLURIPOTENT STEM CELLS

#76
20220408704
2022-12-29

GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH HUMAN OR CHIMERIC THPO

#77
20220386573
2022-12-08

HUMANIZED MOUSE MODEL WITH HUMAN IMMUNE SYSTEM

#78
20220354098
2022-11-10

Genetically Modified Non-Human Animals and Methods of Use Thereof

#79
20220330530
2022-10-20

METHOD OF MAKING HUMAN MOUSE XENOGRAFTS

#80
20220312748
2022-10-06

HUMANIZED TRANSGENIC MOUSE MODEL

#81
20220279767
2022-09-08

TRANSGENIC SWINE, METHODS OF MAKING AND USES THEREOF, AND METHODS OF MAKING HUMAN IMMUNE SYSTEM MICE

#82
20220256821
2022-08-18

ZEBRAFISH DELETION AND COMPOUND MUTANTS AND USES THEREOF

#83
20220248663
2022-08-11

MOSQUITO EGG CRYOPRESERVATION

#84
20220225597
2022-07-21

MOUSE MODEL FOR ASSESSING TOXICITIES ASSOCIATED WITH IMMUNOTHERAPIES

#85
20220217956
2022-07-14

Rodent Model Of Increased Bone Mineral Density

#86
20220214330
2022-07-07

Humanized mouse models for assessing immune cell therapy

#87
20220214327
2022-07-07

Method and composition for sorting out of cell comprising a modified gene

#88
20220204995
2022-06-30

NON-DISRUPTIVE GENE TARGETING

#89
20220201992
2022-06-30

Compositions and methods for producing genetically modified animals

#90
20220192164
2022-06-23

ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATION

#91
20220167600
2022-06-02

METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS

#92
20220167597
2022-06-02

Method for integrating biological tissues with a vascular system

#93
20220127639
2022-04-28

NON-HLA MATCHED HUMANIZED NSG MOUSE MODEL WITH PATIENT-DERIVED XENOGRAFT

#94
20220127638
2022-04-28

NON-HLA MATCHED HUMANIZED NSG MOUSE MODEL WITH PATIENT-DERIVED XENOGRAFT

#95
20220095596
2022-03-31

USE OF ECM1 GENE-KNOCKOUT MOUSE IN SCREENING OF ANTI-HEPATIC FIBROSIS DRUG

#96
20220087233
2022-03-24

NON-HUMAN ANIMAL MODELS OF SÉZARY SYNDROME

#97
20220049221
2022-02-17

METHODS FOR GENERATING FUNCTIONAL HEMATOPOIETIC STEM CELLS

#98
20220031756
2022-02-03

Stem cells for wound healing

#99
20220008480
2022-01-13

TRANSGENIC PIG ISLETS AND USES THEREOF FOR TREATING DIABETES

#100
20220007620
2022-01-13

ANIMAL MODEL FOR AMPLIFYING HUMAN OR ANIMAL CIRCULATING TUMOR CELLS

#101
20220002678
2022-01-06

COMPOSITION FOR RECONSTITUTING HUMAN SKIN TISSUE HAVING HAIR FOLLICLES, HUMAN SKIN TISSUE MODEL ANIMAL, AND PRODUCTION METHOD THEREOF

#102
20220000084
2022-01-06

Genetically Modified Mice and Engraftment

#103
20210405031
2021-12-30

SMALL ANIMAL MODELS FOR IN VIVO TESTING OF POLYOMAVIRUS THERAPEUTICS

#104
20210395696
2021-12-23

ISOLATED NASOPHARYNGEAL CARCINOMA CELLS AND DERIVATIVES PREPARED THEREOF

#105
20210380951
2021-12-09

RNA-BASED METHODS TO LAUNCH HEPATITIS B VIRUS INFECTION

#106
20210368752
2021-12-02

Genetically modified non-human animals and methods of use thereof

#107
20210355162
2021-11-18

MODULATION OF ANTIGEN IMMUNOGENICITY BY DELETING EPITOPES RECOGNIZED BY NKT CELLS

#108
20210352877
2021-11-18

Non-human animal having human IL-34 and use Thereof

#109
20210337775
2021-11-04

USE OF AN EGG GRAFTED WITH TUMOR CELLS IN ORDER TO STUDY THE ANTI-CANCER EFFECTIVENESS OF IMMUNE THERAPIES IN THE ABSENCE OF IMMUNE EFFECTOR CELLS OTHER THAN THOSE IN THE GRAFTED EGG

#110
20210329895
2021-10-28

Mouse having a humanized B-cell activating factor gene

#111
20210301349
2021-09-30

COMPOSITIONS AND METHODS FOR TREATING A TUMOR SUPPRESSOR DEFICIENT CANCER

#112
20210284962
2021-09-16

GENERATION OF A POPULATION OF HINDBRAIN CELLS AND HINDBRAIN-LIKE ORGANOIDS FROM PLURIPOTENT STEM CELLS

#113
20210283185
2021-09-16

METHODS AND MATERIALS FOR IMPROVING TRANSPLANT OUTCOMES

#114
20210277102
2021-09-09

COMPOSITIONS AND METHODS FOR TREATING A TUMOR SUPPRESSOR DEFICIENT CANCER

#115
20210260169
2021-08-26

TELOMERASE REVERSE TRANSCRIPTASE-BASED THERAPIES

#116
20210259221
2021-08-26

IMMUNODEFICIENT MOUSE

#117
20210251201
2021-08-19

Non-human animals having a humanized signal-regulatory protein gene

#118
20210251199
2021-08-19

NON-HUMAN VERTEBRATE COMPRISING HUMAN LIVER CELLS TRANSPLANTED THEREIN AND METHOD FOR PRODUCING THE SAME

#119
20210227809
2021-07-29

GENERATION OF HUMAN ENDODERMAL ORGANS IN PIG MODEL USING LINEAGE RESTRICTED ENDODERMAL PRECURSORS

#120
20210214752
2021-07-15

NON-DISRUPTIVE GENE TARGETING

#121
20210161113
2021-06-03

NON-HUMAN ANIMALS HAVING A HUMANIZED A PROLIFERATION-INDUCING LIGAND GENE

#122
20210161112
2021-06-03

Mouse having a humanized cluster of differentiation 47 gene

#123
20210153484
2021-05-27

Humanized Mouse Model

#124
20210147810
2021-05-20

SINGLE LUNG CELL-DERIVED ORGANOIDS

#125
20210147809
2021-05-20

Single kidney cell-derived organoids

#126
20210130846
2021-05-06

Genetic modification of rats

#127
20210128752
2021-05-06

Method for culturing 3-dimensional lung cancer organoid and method for preparing patient-derived xenograft animal model using same

#128
20210112791
2021-04-22

Humanized M-CSF mice

#129
20210112788
2021-04-22

Production of fertile XY female animals by silencing of genes on the Y chromosome

#130
20210105982
2021-04-15

IMMUNODEFICIENT NON-HUMAN ANIMAL

#131
20210100229
2021-04-08

Non-human animals expressing humanized CD3 complex

#132
20210092942
2021-04-01

NOVEL IMMUNODEFICIENT RAT FOR MODELING HUMAN CANCER

#133
20210052655
2021-02-25

PRODUCTION AND USE OF RED BLOOD CELLS

#134
20210051926
2021-02-25

Method for preparing a large animal model with peritoneal carcinomatosis

#135
20210047428
2021-02-18

METHOD FOR GENERATING ANTIBODIES WITH IMPROVED SPECIFICITY AND/OR AFFINITY

#136
20210030811
2021-02-04

Use of alveolar or airway organoids for the treatment of lung diseases and disorders

#137
20210015863
2021-01-21

Compositions and methods for delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse

#138
20210015439
2021-01-21

Molecular imaging method for evaluating liver regeneration capacity after ALPPS operation

#139
20200385674
2020-12-10

EFFICIENT DERIVATION OF STABLE PLURIPOTENT BOVINE EMBRYONIC STEM CELLS

#140
20200359609
2020-11-19

Genetically modified non-human animals and methods relating to complement dependent cytotoxicity

#141
20200318065
2020-10-08

In vitro methods of differentiating stem cells into neurons and neurons generated using the same

#142
20200315148
2020-10-08

Method for producing chimeric animal

#143
20200315147
2020-10-08

NON-HUMAN ANIMAL AND METHOD FOR PRODUCING SAME

#144
20200309776
2020-10-01

HLA G-MODIFIED CELLS AND METHODS

#145
20200308585
2020-10-01

TARGETING GLIOBLASTOMA STEM CELLS THROUGH THE TLX-TET3 AXIS

#146
20200282210
2020-09-10

Methods of Generating Mature Human Muscle Fibers

#147
20200281174
2020-09-10

MicroRNA inhibitor therapy in systemic lupus erythematosus

#148
20200275642
2020-09-03

Non-human animals expressing humanized CD3 complex

#149
20200275641
2020-09-03

GENERATION AND CORRECTION OF A HUMANIZED MOUSE MODEL WITH A DELETION OF DYSTROPHIN EXON 44

#150
20200268793
2020-08-27

METHODS AND COMPOSITIONS FOR ALLEVIATING CYTOKINE RELEASE SYNDROME

#151
20200261619
2020-08-20

Construct having structure and cell mass linked together

#152
20200237826
2020-07-30

Methods and materials for producing T cells

#153
20200236916
2020-07-30

IMMUNODEFICIENT MICE EXPRESSING HUMAN INTERLEUKIN 15

#154
20200236913
2020-07-30

Chimeric mouse comprising stably transplanted bat cells

#155
20200229410
2020-07-23

Genetically modified non-human animals and methods of use thereof

#156
20200208119
2020-07-02

Avian induced pluripotent stem cells and their use

#157
20200187468
2020-06-18

Non-human animals having a humanized signal-regulatory protein gene

#158
20200164195
2020-05-28

Methods for cancer treatment

#159
20200110071
2020-04-09

PERSONALIZED ANTI-CANCER AGENT SCREENING SYSTEM

#160
20200093105
2020-03-26

Genetically modified non-human animals and methods of use thereof

#161
20200060245
2020-02-27

NSG mice lacking MHC class I and class II

#162
20200060244
2020-02-27

Genetically modified non-human animals expressing human EPO

#163
20200041512
2020-02-06

HLA G-modified cells and methods

#164
20200029540
2020-01-30

Transplantation method to increase the establishment rate of human tumors in immunodeficient mice

#165
20200029539
2020-01-30

Rat model of down syndrome and method for producing same

#166
20200023078
2020-01-23

ANIMAL MODEL SYSTEM AND USES THEREOF

#167
20200017882
2020-01-16

ENGINEERING OF HUMANIZED CAR T-CELL AND PLATELETS BY GENETIC COMPLEMENTATION

#168
20200017834
2020-01-16

Cell and utilization thereof

#169
20200011878
2020-01-09

Anti-NRP1 antibody screening method

#170
20200011856
2020-01-09

Method for Determining the Effectiveness of Treatment for the Prevention of Heartworm Disease

#171
20200008406
2020-01-09

Fumarylacetoacetate hydrolase (FAH)-deficient and immunodeficient rats and uses thereof

#172
20190376029
2019-12-12

Methods of engineering human induced pluripotent stem cells to produce liver tissue

#173
20190351076
2019-11-21

TUMOR CELL XENOGRAFT MODEL IN ZEBRAFISH, AND METHODS OF CONSTRUCTING AND USING THE SAME

#174
20190351075
2019-11-21

Genetically modified mouse comprising a chimeric TIGIT

#175
20190345212
2019-11-14

HYBRID NUCLEIC ACID MOLECULES AND THEIR USE

#176
20190335724
2019-11-07

Urokinase-type plasminogen activator transgenic mouse

#177
20190328907
2019-10-31

Genetically modified non-human animal with human or chimeric TIGIT

#178
20190320633
2019-10-24

HUMANIZED MOUSE MODEL WITH IMPROVED HUMAN INNATE IMMUNE CELL DEVELOPMENT

#179
20190320631
2019-10-24

Immunodeficient non-human animal

#180
20190316156
2019-10-17

Complexes for gene deletion and editing

#181
20190316149
2019-10-17

Genetic modification of rats

#182
20190309264
2019-10-10

Three Dimensional Bioprinted Tumor Models for Drug Testing

#183
20190297862
2019-10-03

Genetically modified mice and engraftment

#184
20190255154
2019-08-22

Methods and materials for using butyrylcholinesterases to treat cancer

#185
20190254266
2019-08-22

Engineering of Humanized Kidney by Genetic Complementation

#186
20190241908
2019-08-08

Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (DNase) activity

#187
20190224293
2019-07-25

Vaccine comprising drug and parasite administration

#188
20190211372
2019-07-11

Organoid with metastatic property and use thereof

#189
20190208754
2019-07-11

METHOD OF CONSTRUCTING HUMANIZED MURINE MODEL OF CHRONIC VIRAL HEPATITIS USING STEM CELL

#190
20190183101
2019-06-20

METHODS AND COMPOSITIONS RELATING TO IMPROVED HUMAN RED BLOOD CELL SURVIVAL IN GENETICALLY MODIFIED IMMUNODEFICIENT NON-HUMAN ANIMALS

#191
20190177695
2019-06-13

Methods for generating functional hematopoietic stem cells

#192
20190161735
2019-05-30

Human fibrolamellar hepatocellular carcinomas (hFL-HCCs)

#193
20190151362
2019-05-23

Compositions and methods of cellular immunotherapy

#194
20190136201
2019-05-09

STEM CELLS FOR MODELING TYPE 2 DIABETES

#195
20190134118
2019-05-09

Adeno-associated virus compositions for restoring HBB gene function and methods of use thereof

#196
20190133093
2019-05-09

ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATION

#197
20190124897
2019-05-02

Non-human animals having a humanized B-cell activating factor gene

#198
20190124895
2019-05-02

Non-human animals having a humanized signal-regulatory protein gene

#199
20190117788
2019-04-25

High-affinity anti-human folate receptor beta antibodies and methods of use

#200
20190106710
2019-04-11

Oncogenic Models Based on Delivery and Use of the CRISPR-Cas Systems, Vectors and Compositions

#201
20190082663
2019-03-21

Genetically modified non-human animals and methods of use thereof

#202
20190054121
2019-02-21

Compositions and methods for delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse

#203
20190046572
2019-02-14

Compositions and methods for delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse

#204
20190032055
2019-01-31

Targeting glioblastoma stem cells through the TLX-TET3 axis

#205
20190029235
2019-01-31

EFFICIENT, SCALABLE PATIENT-DERIVED XENOGRAFT SYSTEM BASED ON A CHICK CHORIOALLANTOIC MEMBRANE (CAM) IN VIVO MODEL

#206
20190016767
2019-01-17

Multimodal trail molecules expressed in T cells

#207
20190014758
2019-01-17

HUMANIZED MOUSE MODEL

#208
20190010519
2019-01-10

Compositions and methods for enhanced genome editing

#209
20190002832
2019-01-03

HUMANIZED MOUSE MODEL OF MYASTHENIA GRAVIS AND MSC THERAPY

#210
20180368373
2018-12-27

Animal study model for cancer

#211
20180360004
2018-12-20

Method for producing chimeric animal

#212
20180334487
2018-11-22

Compositions for use in recovering or ameliorating deterioration of physiological functions due to aging

#213
20180326096
2018-11-15

Mode of inducing renal transplant rejection on animals and its manufacturing approach

#214
20180325947
2018-11-15

USE OF MAPK INHIBITORS TO REDUCE LOSS OF HEMATOPOIETIC STEM CELLS DURING EX VIVO CULTURE AND/OR GENETIC MANIPULATION

#215
20180295822
2018-10-18

High-throughput mouse model for optimizing antibody affinities

#216
20180295820
2018-10-18

Genetically modified non-human animals and methods of use thereof

#217
20180291343
2018-10-11

Methods for engineering allogeneic T cell to increase their persistence and/or engraftment into patients

#218
20180289841
2018-10-11

Preclinical model of neonatal necrotizing enterocolitis

#219
20180289840
2018-10-11

Method for Evaluating Hematological Toxicity of Drug Under Evaluation, and Model for Evaluating Hematological Toxicity of Drug Under Evaluation

#220
20180288982
2018-10-11

Method for measuring tumor burden in patient derived xenograft (PDX) mice

#221
20180282762
2018-10-04

Optimized CRISPR/cas9 systems and methods for gene editing in stem cells

#222
20180273628
2018-09-27

GENERATION OF HUMAN MACROPHAGES IN IMMUNODEFICIENT NON-HUMAN HOSTS

#223
20180271070
2018-09-27

Method for generating a humanized transgenic mouse comprising a human APRIL gene

#224
20180271069
2018-09-27

Generation and correction of a humanized mouse model with a deletion of dystrophin exon 44

#225
20180255752
2018-09-13

Mouse lymphoma cell line and animal model of human high grade B-cell lymphoma

#226
20180255751
2018-09-13

Delivery, use and therapeutic applications of the CRISPR-cas systems and compositions for modeling mutations in leukocytes

#227
20180249689
2018-09-06

Method of using mouse having a humanized cluster of differentiation 47 gene

#228
20180244771
2018-08-30

Immunity enhancing agent for cancer by Allergin-1 antagonist

#229
20180237861
2018-08-23

PERSONALIZED TREATMENT OF DISEASES AND DISORDERS

#230
20180228839
2018-08-16

Methods and materials for producing T cells

#231
20180216112
2018-08-02

PROCESS FOR INDUCING RESISTANCE TO DIPHTHERIA TOXIN IN HUMAN CELLS, PRODUCTS AND USES THEREOF

#232
20180213755
2018-08-02

Human IL-15-secreting immunodeficient mouse

#233
20180195046
2018-07-12

Induced extended pluripotent stem cells, method of making and using

#234
20180192623
2018-07-12

Non-human animal having human CD3 gene substituted for endogenous CD3 gene

#235
20180187210
2018-07-05

Non-HLA matched humanized NSG mouse model with patient-derived xenograft

#236
20180184629
2018-07-05

Genetically modified non-human animals and methods relating to complement dependent cytotoxicity

#237
20180177827
2018-06-28

Production and use of red blood cells

#238
20180177164
2018-06-28

Method for producing blood chimeric animal

#239
20180160662
2018-06-14

Transgenic Immunodeficient Mouse Expressing Human SIRP-alpha

#240
20180153145
2018-06-07

HUMANIZED MICE AND USES THEREOF

#241
20180139941
2018-05-24

Non-human animals having a humanized signal-regulatory protein gene

#242
20180116191
2018-05-03

Method for producing non-human large mammal or fish each capable of producing gamete originated from different individual

#243
20180092994
2018-04-05

Host cells with artificial endosymbionts

#244
20180084766
2018-03-29

METHODS AND COMPOSITIONS RELATING TO AN EMBRYONIC STEM CELL-BASED TUMOR MODEL

#245
20180020647
2018-01-25

Genetically Modified Non-Human Animals And Methods Of Use Thereof

#246
20180009843
2018-01-11

Modulation of antigen immunogenicity by deleting epitopes recognized by NKT cells

#247
20170360963
2017-12-21

In vivo methods for identifying cancer-associated immunotherapy targets

#248
20170332610
2017-11-23

METHODS FOR BREAKING IMMUNOLOGICAL TOLERANCE USING MULTIPLE GUIDE RNAS

#249
20170321214
2017-11-09

DEAD GUIDES FOR CRISPR TRANSCRIPTION FACTORS

#250
20170306296
2017-10-26

Method for reestablishment of pluripotent stem cells

#251
20170298116
2017-10-19

Method for producing antigen-specific B cells and their use for the production of hybridoma cells and monoclonal antibodies

#252
20170295762
2017-10-19

Methods and compositions for generating a mouse

#253
20170292952
2017-10-12

HLA G-modified cells and methods

#254
20170273285
2017-09-28

Humanized M-CSF mice

#255
20170273283
2017-09-28

Methods for establishing animal model of hepatocellular carcinoma bone metastasis

#256
20170267978
2017-09-21

INDUCED PLURIPOTENT STEM CELLS

#257
20170267970
2017-09-21

Three-Dimensional Hydrogels that Support Growth of Physiologically Relevant Tissue and Methods of Use Thereof

#258
20170266255
2017-09-21

Pharmaceutical composition for treating bone diseases which comprises protein comprising Frizzled 1, Frizzled 2 or Frizzled 7 extracellular cysteine-rich domain

#259
20170265442
2017-09-21

Non-human animals having a humanized signal-regulatory protein gene

#260
20170265441
2017-09-21

METHOD FOR PRODUCING ANIMAL MODEL OF OSTEOBLASTIC BONE METASTASIS

#261
20170232075
2017-08-17

Telomerase reverse transcriptase-based therapies

#262
20170218399
2017-08-03

Production of fertile XY female mice from XY mouse ES cells

#263
20170215393
2017-08-03

Animal models, cell lines and methods for screening hepatitis C virus vaccines

#264
20170215392
2017-08-03

Methods and compositions for perturbing gene expression in hematopoietic stem cell lineages in vivo

#265
20170209493
2017-07-27

Stem cells for wound healing

#266
20170198261
2017-07-13

Single cell-derived organoids

#267
20170191038
2017-07-06

TGFß SIGNALING INDEPENDENT NAÏVE INDUCED PLURIPOTENT STEM CELLS, METHODS OF MAKING AND USE

#268
20170189453
2017-07-06

Transgenic pig islets and uses thereof for treating diabetes

#269
20170188556
2017-07-06

Non-human animals having a humanized B-cell activating factor gene

#270
20170182098
2017-06-29

Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder

#271
20170182097
2017-06-29

Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder

#272
20170172121
2017-06-22

Genetically modified mice and engraftment

#273
20170164588
2017-06-15

NON-HUMAN ANIMALS EXPRESSING HUMANIZED CD3 COMPLEX

#274
20170159024
2017-06-08

METHOD FOR PRODUCING TISSUE AND ORGAN

#275
20170156297
2017-06-08

ANIMAL MODEL FOR STUDYING NEUROBLASTOMAS

#276
20170152526
2017-06-01

ENGINEERING OF HUMANIZED CAR T-CELL AND PLATELETS BY GENETIC COMPLEMENTATION

#277
20170118965
2017-05-04

HUMANIZED MOUSE MODELS AND USES THEREOF

#278
20170106101
2017-04-20

METHODS INVOLVING MACROPHAGE TUMOR CELL FUSION HYBRIDS

#279
20170099813
2017-04-13

METHOD OF GENERATING STERILE TERMINAL SIRES IN LIVESTOCK AND ANIMALS PRODUCED THEREBY

#280
20170079250
2017-03-23

Production of fertile XY female animals by silencing of genes on the Y chromosome

#281
20170055505
2017-03-02

Rodent model of prostate cancer

#282
20170055504
2017-03-02

Mouse model of hyperuricemia

#283
20170037429
2017-02-09

Genetic modification of rats

#284
20170027140
2017-02-02

Human SIRPα transgenic mice and their methods of use

#285
20170002064
2017-01-05

VH4 ANTIBODIES AGAINST GRAY MATTER NEURON AND ASTROCYTE

#286
20160374321
2016-12-29

Non-human animals having a humanized signal-regulatory protein gene

#287
20160374320
2016-12-29

High-throughput mouse model for optimizing antibody affinities

#288
20160362656
2016-12-15

Feeder-free method for culture of bovine and porcine spermatogonial stem cells

#289
20160360736
2016-12-15

COMPOSITIONS AND METHODS FOR PRODUCING GENETICALLY MODIFIED ANIMALS

#290
20160360735
2016-12-15

Animal model of nash-induced hepatocellular carcinoma and methods for developing specific therapeutics

#291
20160355824
2016-12-08

Method for selectively inhibiting ACAT1 in the treatment of obesity, metabolic syndrome, and atherosclerosis

#292
20160345549
2016-12-01

NON-HUMAN ANIMALS HAVING A HUMANIZED CLUSTER OF DIFFERENTIATION 47 GENE

#293
20160345548
2016-12-01

Genetically modified non-human animals and methods relating to innate immune system response detection

#294
20160345547
2016-12-01

Non-human animals having a disruption in a C9ORF72 locus

#295
20160333319
2016-11-17

Population of isolated chicken cells reprogrammed from somatic cells

#296
20160333064
2016-11-17

Biodegradable matrix comprising stem cells that express soluble TRAIL

#297
20160324130
2016-11-10

ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATION

#298
20160317681
2016-11-03

Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder

#299
20160316729
2016-11-03

Methods and compositions for generating a mouse

#300
20160316728
2016-11-03

ES Cell-Derived Mice From Diploid Host Embryo Injection