ClassID:

2182

A01K2217/054 - CPC Classification

Classification description:

Genetically modified animals; Animals comprising random inserted nucleic acids (transgenic) inducing loss of function

Sub-classes:
Recent Application in this class:
#1
20260130347
2026-05-14

TRANSGENIC ANIMALS AND RECOMBINANT HOST CELLS COMPRISING SPECIFIC GENE VARIANTS AND METHODS OF CREATING SAME

#2
20250324954
2025-10-23

METHOD FOR PROMOTING SEXUAL MATURATION OF FISH

#3
20250311705
2025-10-09

METHOD OF GENETIC MANIPULATION OF NEURAL CELLS IN GYRENCEPHALIC FETAL BRAIN AND USES THEREOF

#4
20250280804
2025-09-11

TRANSGENIC ANIMAL HAVING MODIFIED MYOSTATIN GENE

#5
20240415103
2024-12-19

VECTORS, GENETICALLY MODIFIED CELLS, AND GENETICALLY MODIFIED NON-HUMAN ANIMALS COMPRISING THE SAME

#6
20240276957
2024-08-22

METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS

#7
20240229080
2024-07-11

CONTROLLED GENE EXPRESSION METHODS AND MEANS

#8
20240206441
2024-06-27

Method for Constructing Murine Model with Mutations in Csf1r Gene and Application thereof

#9
20240175049
2024-05-30

LONG GERMLINE DH GENES AND LONG HCDR3 ANTIBODIES

#10
20240156069
2024-05-16

GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENCY (SCID)

#11
20240142474
2024-05-02

Opsins as Chemosensory Receptors and Related Methods

#12
20240107988
2024-04-04

DOWN-REGULATION OF ENDOGENOUS GENES

#13
20240065237
2024-02-29

A GENETICALLY MODIFIED IMMUNODEFICIENT MOUSE EXPRESSING HUMAN OR HUMANIZED APP AND MUTATED HUMAN PSEN1

#14
20240041010
2024-02-08

GENERATION OF SURROGATE SIRES AND DAMS BY ABLATION OF ENDOGENOUS GERMLINE

#15
20240008460
2024-01-11

JAK3 GENE-MUTATED, SEVERE COMBINED IMMUNODEFICIENCY ANIMAL MODEL AND CONSTRUCTION METHOD THEREFOR

#16
20230309522
2023-10-05

ANIMAL MODEL, METHODS FOR MAKING AND USING THEREOF, AND COMPOSITION FOR TREATING ATAXIA

#17
20220338453
2022-10-27

ENGINEERED CATFISH AND USES THEREOF

#18
20220330532
2022-10-20

NON-HUMAN ANIMALS HAVING A LIMITED LAMBDA LIGHT CHAIN REPERTOIRE EXPRESSED FROM THE KAPPA LOCUS AND USES THEREOF

#19
20220304286
2022-09-29

SYSTEMS AND METHODS FOR IN VIVO DUAL RECOMBINASE-MEDIATED CASSETTE EXCHANGE (dRMCE) AND DISEASE MODELS THEREOF

#20
20220249703
2022-08-11

ARTIFICIAL EXPRESSION CONSTRUCTS FOR SELECTIVELY MODULATING GENE EXPRESSION IN SELECTED NEURONAL CELL POPULATIONS

#21
20220211018
2022-07-07

MULTI-TRANSGENIC PIGS WITH GROWTH HORMONE RECEPTOR KNOCKOUT FOR XENOTRANSPLANTATION

#22
20220195431
2022-06-23

COMPOUNDS AND METHODS FOR REDUCING ATXN3 EXPRESSION

#23
20220167599
2022-06-02

GENETIC MODIFICATION OF PIGS FOR XENOTRANSPLANTATION

#24
20220167598
2022-06-02

Genetically modified rat models for severe combined immunodeficiency (SCID)

#25
20220099659
2022-03-31

Human Genomic Construct Reporter Cells and Mouse Models to Screen Therapeutics against Microglia-expressed Disease Associated Genes

#26
20220098597
2022-03-31

Self-Limiting Noctuids

#27
20220033847
2022-02-03

NON-HUMAN ANIMALS EXPRESSING HUMANIZED C1Q COMPLEX

#28
20220017918
2022-01-20

Synthesis of Non-Native Proteins in Bombyx Mori by Modifying Sericin Expression

#29
20210392864
2021-12-23

Genetically modified rat models for severe combined immunodeficiency (SCID)

#30
20210307304
2021-10-07

Non-human animals models of retinoschisis

#31
20210251201
2021-08-19

Non-human animals having a humanized signal-regulatory protein gene

#32
20210246471
2021-08-12

MODIFICATION OF HEAVY CHAIN FIBROIN IN BOMBYX MORI

#33
20210153485
2021-05-27

Transgenic mouse model of Neurofibromatosis type 1

#34
20210100227
2021-04-08

loss of function rodent model

#35
20210025004
2021-01-28

COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE

#36
20200253173
2020-08-13

FISH AND METHOD FOR PRODUCING FISH

#37
20200236915
2020-07-30

HUMAN ARTIFICIAL CHROMOSOME CONTAINING HUMAN ANTIBODY LAMBDA LIGHT CHAIN GENE AND NON-HUMAN ANIMAL CONTAINING THE HUMAN ARTIFICIAL CHROMOSOME CAPABLE OF GENETIC TRANSMISSION

#38
20200187468
2020-06-18

Non-human animals having a humanized signal-regulatory protein gene

#39
20200187467
2020-06-18

Mouse with cholinergic neuron-specific inactivated ANO1 gene

#40
20200015461
2020-01-16

Transgenic mice with inducible neuron-specific inactivation of HuR gene and method of screening

#41
20190297860
2019-10-03

Repressors of viral infection

#42
20190254266
2019-08-22

Engineering of Humanized Kidney by Genetic Complementation

#43
20190208752
2019-07-11

Animal model of Angelman Syndrome

#44
20190127757
2019-05-02

Long germline DH genes and long HCDR3 antibodies

#45
20190124895
2019-05-02

Non-human animals having a humanized signal-regulatory protein gene

#46
20190101533
2019-04-04

ANIMAL MODEL FOR STUDYING ZCCHC6 IN BONE DISEASE AND DEVELOPMENT

#47
20190100772
2019-04-04

Non-human animals expressing humanized C1Q complex

#48
20190017021
2019-01-17

Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals

#49
20180295822
2018-10-18

High-throughput mouse model for optimizing antibody affinities

#50
20180295819
2018-10-18

Genetically modified rat models for severe combined immunodeficiency (SCID)

#51
20180271069
2018-09-27

Generation and correction of a humanized mouse model with a deletion of dystrophin exon 44

#52
20180255754
2018-09-13

Non-human animal models of retinoschisis

#53
20180195126
2018-07-12

Compositions and methods for determining genetic polymorphisms in the TMEM216 gene

#54
20180139941
2018-05-24

Non-human animals having a humanized signal-regulatory protein gene

#55
20180132458
2018-05-17

TRANSGENIC ANIMAL MODELS FOR CYSTIC FIBROSIS

#56
20180070564
2018-03-15

Genetic modification of pigs for xenotransplantation

#57
20170265442
2017-09-21

Non-human animals having a humanized signal-regulatory protein gene

#58
20170218336
2017-08-03

Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals

#59
20170209541
2017-07-27

Method for treating arthritis using IK factor or nucleic acid encoding IK factor

#60
20170099814
2017-04-13

Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission

#61
20170079253
2017-03-23

Transgenic mice having a human major histocompatibility complex (MHC) phenotype, experimental uses and applications

#62
20160374321
2016-12-29

Non-human animals having a humanized signal-regulatory protein gene

#63
20160374320
2016-12-29

High-throughput mouse model for optimizing antibody affinities

#64
20160345553
2016-12-01

TRANSGENIC MOUSE MODELS FOR MC4R

#65
20160295841
2016-10-13

Production of fertile XY female animals from XY ES cells

#66
20160165861
2016-06-16

Genetically modified cells, tissues, and organs for treating disease

#67
20160135437
2016-05-19

HUMANIZED MOUSE MODEL FOR STUDY OF BONA FIDE HEPATITIS VIRUS INFECTION AND USE THEREOF

#68
20160050896
2016-02-25

Non-human animals having a humanized signal-regulatory protein gene

#69
20150343012
2015-12-03

Treatment of muscular dystrophy

#70
20150296756
2015-10-22

Animal models of neurological disorders

#71
20150128299
2015-05-07

Normalization of the enterohepatic circulation in animals with a chimeric humanized liver

#72
20150089679
2015-03-26

Non-human animals having a humanized signal-regulatory protein gene

#73
20150089678
2015-03-26

Non-human animals having a humanized signal-regulatory protein gene

#74
20150067901
2015-03-05

Production of fertile XY female animals from XY ES cells

#75
20140215644
2014-07-31

Soluble protein CD5 or CD6 for the treatment of cancer or tumor or for use as an adjuvant

#76
20140072975
2014-03-13

Compositions and methods for determining genetic polymorphisms in the TMEM216 gene

#77
20140041062
2014-02-06

Genetically engineered mouse model for autism spectrum disorder having deletion of gene and use thereof

#78
20130031648
2013-01-31

Use of Follistatin-Like Related Gene (FLRG) to Increase Muscle Mass

#79
20120278909
2012-11-01

Compositions and methods for determining genetic polymorphisms in the TMEM216 gene

#80
20120180144
2012-07-12

Animal models of neurological disorders

#81
20120177577
2012-07-12

Genetically modified rat models for severe combined immunodeficiency (SCID)

#82
20120159654
2012-06-21

GENOME EDITING OF GENES INVOLVED IN ADME AND TOXICOLOGY IN ANIMALS

#83
20120159653
2012-06-21

GENOMIC EDITING OF GENES INVOLVED IN MACULAR DEGENERATION

#84
20120148565
2012-06-14

INCREASING LIFESPAN BY MODULATION OF WWP-1 AND UBC-18

#85
20110307968
2011-12-15

Production of fertile XY animals from XY ES cells

#86
20110296540
2011-12-01

ASSAY FOR SCREENING ANTIDEPRESSANTS

#87
20110142862
2011-06-16

TRANSGENIC MICE HAVING A HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) PHENOTYPE, EXPERIMENTAL USES AND APPLICATIONS

#88
20110093963
2011-04-21

Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals

#89
20110093960
2011-04-21

Methods of identifying agents that ameliorate or modulate effects of PRO1328 gene disruptions

#90
20110072524
2011-03-24

Transgenic Mouse Lacking Endogenous FVIII and VWF - A Model of Hemophilia A

#91
20110067121
2011-03-17

Transgenic mice having a human major histocompatibility complex (MHC) phenotype, experimental uses and applications

#92
20110030078
2011-02-03

TRYPANOSOME RESISTANT NON-HUMAN TRANSGENIC ANIMAL

#93
20110016540
2011-01-20

GENOME EDITING OF GENES ASSOCIATED WITH TRINUCLEOTIDE REPEAT EXPANSION DISORDERS IN ANIMALS

#94
20100218264
2010-08-26

Method of deleting an IgM gene in an isolated rat cell

#95
20100169989
2010-07-01

Methods of increasing muscle mass using follistatin-like related gene (FLRG)

#96
20100132055
2010-05-27

ANIMAL MODEL FOR THE SELECTION AND VALIDATION OF AGENTS ACTIVE AGAINST PULMONARY EMPHYSEMA AND COLORECTAL CANCER

#97
20100115637
2010-05-06

Models of thrombotic thrombocytopenic purpura and methods of use thereof

#98
20100031378
2010-02-04

Novel gene disruptions, compositions and methods relating thereto

#99
20090083868
2009-03-26

Increasing lifespan by modulation of WWP-1 and UBC-18

#100
20090081128
2009-03-26

Model of Alzheimer's Disease

#101
20090077680
2009-03-19

Genetically Engineered and Photyped Mice and Stem Cell Clones for Producing the Same

#102
20090053210
2009-02-26

Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals

#103
20080317743
2008-12-25

Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission

#104
20080200382
2008-08-21

Use of AIM3 acting as a tumor suppressor

#105
20060161995
2006-07-20

Artificial human chromosome containing human antibody a light chain gene

#106
20060046250
2006-03-02

Novel use of aim 3 acting as a tumor suppressor

#107
20060015958
2006-01-19

Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission

#108
20050114910
2005-05-26

Transgenic mice having a human major histocompatability complex (MHC) phenotype, experimental uses and applications

#109
15141689
2020-06-09

A4B2 nicotinic acetylcholine receptors with reduced or increased nicotine sensitivity and transgenic mouse model for the same