2182 ⎘
Genetically modified animals; Animals comprising random inserted nucleic acids (transgenic) inducing loss of function
Sub-classes:TRANSGENIC ANIMALS AND RECOMBINANT HOST CELLS COMPRISING SPECIFIC GENE VARIANTS AND METHODS OF CREATING SAME
#2METHOD FOR PROMOTING SEXUAL MATURATION OF FISH
#3METHOD OF GENETIC MANIPULATION OF NEURAL CELLS IN GYRENCEPHALIC FETAL BRAIN AND USES THEREOF
#4TRANSGENIC ANIMAL HAVING MODIFIED MYOSTATIN GENE
#5VECTORS, GENETICALLY MODIFIED CELLS, AND GENETICALLY MODIFIED NON-HUMAN ANIMALS COMPRISING THE SAME
#6METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS
#7CONTROLLED GENE EXPRESSION METHODS AND MEANS
#8Method for Constructing Murine Model with Mutations in Csf1r Gene and Application thereof
#9LONG GERMLINE DH GENES AND LONG HCDR3 ANTIBODIES
#10GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENCY (SCID)
#11Opsins as Chemosensory Receptors and Related Methods
#12DOWN-REGULATION OF ENDOGENOUS GENES
#13A GENETICALLY MODIFIED IMMUNODEFICIENT MOUSE EXPRESSING HUMAN OR HUMANIZED APP AND MUTATED HUMAN PSEN1
#14GENERATION OF SURROGATE SIRES AND DAMS BY ABLATION OF ENDOGENOUS GERMLINE
#15JAK3 GENE-MUTATED, SEVERE COMBINED IMMUNODEFICIENCY ANIMAL MODEL AND CONSTRUCTION METHOD THEREFOR
#16ANIMAL MODEL, METHODS FOR MAKING AND USING THEREOF, AND COMPOSITION FOR TREATING ATAXIA
#17ENGINEERED CATFISH AND USES THEREOF
#18NON-HUMAN ANIMALS HAVING A LIMITED LAMBDA LIGHT CHAIN REPERTOIRE EXPRESSED FROM THE KAPPA LOCUS AND USES THEREOF
#19SYSTEMS AND METHODS FOR IN VIVO DUAL RECOMBINASE-MEDIATED CASSETTE EXCHANGE (dRMCE) AND DISEASE MODELS THEREOF
#20ARTIFICIAL EXPRESSION CONSTRUCTS FOR SELECTIVELY MODULATING GENE EXPRESSION IN SELECTED NEURONAL CELL POPULATIONS
#21MULTI-TRANSGENIC PIGS WITH GROWTH HORMONE RECEPTOR KNOCKOUT FOR XENOTRANSPLANTATION
#22COMPOUNDS AND METHODS FOR REDUCING ATXN3 EXPRESSION
#23GENETIC MODIFICATION OF PIGS FOR XENOTRANSPLANTATION
#24Genetically modified rat models for severe combined immunodeficiency (SCID)
#25Human Genomic Construct Reporter Cells and Mouse Models to Screen Therapeutics against Microglia-expressed Disease Associated Genes
#26Self-Limiting Noctuids
#27NON-HUMAN ANIMALS EXPRESSING HUMANIZED C1Q COMPLEX
#28Synthesis of Non-Native Proteins in Bombyx Mori by Modifying Sericin Expression
#29Genetically modified rat models for severe combined immunodeficiency (SCID)
#30Non-human animals models of retinoschisis
#31Non-human animals having a humanized signal-regulatory protein gene
#32MODIFICATION OF HEAVY CHAIN FIBROIN IN BOMBYX MORI
#33Transgenic mouse model of Neurofibromatosis type 1
#34loss of function rodent model
#35COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE
#36FISH AND METHOD FOR PRODUCING FISH
#37HUMAN ARTIFICIAL CHROMOSOME CONTAINING HUMAN ANTIBODY LAMBDA LIGHT CHAIN GENE AND NON-HUMAN ANIMAL CONTAINING THE HUMAN ARTIFICIAL CHROMOSOME CAPABLE OF GENETIC TRANSMISSION
#38Non-human animals having a humanized signal-regulatory protein gene
#39Mouse with cholinergic neuron-specific inactivated ANO1 gene
#40Transgenic mice with inducible neuron-specific inactivation of HuR gene and method of screening
#41Repressors of viral infection
#42Engineering of Humanized Kidney by Genetic Complementation
#43Animal model of Angelman Syndrome
#44Long germline DH genes and long HCDR3 antibodies
#45Non-human animals having a humanized signal-regulatory protein gene
#46ANIMAL MODEL FOR STUDYING ZCCHC6 IN BONE DISEASE AND DEVELOPMENT
#47Non-human animals expressing humanized C1Q complex
#48Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
#49High-throughput mouse model for optimizing antibody affinities
#50Genetically modified rat models for severe combined immunodeficiency (SCID)
#51Generation and correction of a humanized mouse model with a deletion of dystrophin exon 44
#52Non-human animal models of retinoschisis
#53Compositions and methods for determining genetic polymorphisms in the TMEM216 gene
#54Non-human animals having a humanized signal-regulatory protein gene
#55TRANSGENIC ANIMAL MODELS FOR CYSTIC FIBROSIS
#56Genetic modification of pigs for xenotransplantation
#57Non-human animals having a humanized signal-regulatory protein gene
#58Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
#59Method for treating arthritis using IK factor or nucleic acid encoding IK factor
#60Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#61Transgenic mice having a human major histocompatibility complex (MHC) phenotype, experimental uses and applications
#62Non-human animals having a humanized signal-regulatory protein gene
#63High-throughput mouse model for optimizing antibody affinities
#64TRANSGENIC MOUSE MODELS FOR MC4R
#65Production of fertile XY female animals from XY ES cells
#66Genetically modified cells, tissues, and organs for treating disease
#67HUMANIZED MOUSE MODEL FOR STUDY OF BONA FIDE HEPATITIS VIRUS INFECTION AND USE THEREOF
#68Non-human animals having a humanized signal-regulatory protein gene
#69Treatment of muscular dystrophy
#70Animal models of neurological disorders
#71Normalization of the enterohepatic circulation in animals with a chimeric humanized liver
#72Non-human animals having a humanized signal-regulatory protein gene
#73Non-human animals having a humanized signal-regulatory protein gene
#74Production of fertile XY female animals from XY ES cells
#75Soluble protein CD5 or CD6 for the treatment of cancer or tumor or for use as an adjuvant
#76Compositions and methods for determining genetic polymorphisms in the TMEM216 gene
#77Genetically engineered mouse model for autism spectrum disorder having deletion of gene and use thereof
#78Use of Follistatin-Like Related Gene (FLRG) to Increase Muscle Mass
#79Compositions and methods for determining genetic polymorphisms in the TMEM216 gene
#80Animal models of neurological disorders
#81Genetically modified rat models for severe combined immunodeficiency (SCID)
#82GENOME EDITING OF GENES INVOLVED IN ADME AND TOXICOLOGY IN ANIMALS
#83GENOMIC EDITING OF GENES INVOLVED IN MACULAR DEGENERATION
#84INCREASING LIFESPAN BY MODULATION OF WWP-1 AND UBC-18
#85Production of fertile XY animals from XY ES cells
#86ASSAY FOR SCREENING ANTIDEPRESSANTS
#87TRANSGENIC MICE HAVING A HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) PHENOTYPE, EXPERIMENTAL USES AND APPLICATIONS
#88Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
#89Methods of identifying agents that ameliorate or modulate effects of PRO1328 gene disruptions
#90Transgenic Mouse Lacking Endogenous FVIII and VWF - A Model of Hemophilia A
#91Transgenic mice having a human major histocompatibility complex (MHC) phenotype, experimental uses and applications
#92TRYPANOSOME RESISTANT NON-HUMAN TRANSGENIC ANIMAL
#93GENOME EDITING OF GENES ASSOCIATED WITH TRINUCLEOTIDE REPEAT EXPANSION DISORDERS IN ANIMALS
#94Method of deleting an IgM gene in an isolated rat cell
#95Methods of increasing muscle mass using follistatin-like related gene (FLRG)
#96ANIMAL MODEL FOR THE SELECTION AND VALIDATION OF AGENTS ACTIVE AGAINST PULMONARY EMPHYSEMA AND COLORECTAL CANCER
#97Models of thrombotic thrombocytopenic purpura and methods of use thereof
#98Novel gene disruptions, compositions and methods relating thereto
#99Increasing lifespan by modulation of WWP-1 and UBC-18
#100Model of Alzheimer's Disease
#101Genetically Engineered and Photyped Mice and Stem Cell Clones for Producing the Same
#102Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
#103Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#104Use of AIM3 acting as a tumor suppressor
#105Artificial human chromosome containing human antibody a light chain gene
#106Novel use of aim 3 acting as a tumor suppressor
#107Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#108Transgenic mice having a human major histocompatability complex (MHC) phenotype, experimental uses and applications
#109A4B2 nicotinic acetylcholine receptors with reduced or increased nicotine sensitivity and transgenic mouse model for the same