ClassID:

2183

A01K2217/056 - CPC Classification

Classification description:

Genetically modified animals; Animals comprising random inserted nucleic acids (transgenic) inducing loss of function due to mutation of coding region of the transgene (dominant negative)

Recent Application in this class:
#1
20260151513
2026-06-04

COMPOSITIONS AND METHODS FOR THE TREATMENT OF LEUKODYSTROPHY AND WHOLE ANIMAL AND CELLULAR MODELS FOR IDENTIFYING EFFICACIOUS AGENTS FOR TREATMENT OF THE SAME

#2
20260083106
2026-03-26

HUMANIZED IMMUNODEFICIENT MOUSE MODELS

#3
20260041074
2026-02-12

HIGH-WEIGHT BLACK SOLDIER FLY LARVAE, METHODS OF PRODUCING SAME AND USE THEREOF

#4
20240315220
2024-09-26

GENETICALLY MODIFIED MOUSE EXPRESSING HUMAN APOE4 AND MOUSE TREM2 P.R47H AND METHODS OF USE THEREOF

#5
20240299512
2024-09-12

IMMUNOTHERAPY COMPOSITIONS AND METHODS FOR TREATMENT OF TAUOPATHY AND TRANSGENIC MOUSE

#6
20240197845
2024-06-20

IMMUNOTHERAPY COMPOSITIONS AND METHODS FOR TREATMENT OF TAUOPATHY AND TRANSGENIC MOUSE

#7
20240156069
2024-05-16

GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENCY (SCID)

#8
20230349888
2023-11-02

A HIGH-THROUGHPUT SCREENING METHOD TO DISCOVER OPTIMAL GRNA PAIRS FOR CRISPR-MEDIATED EXON DELETION

#9
20230200362
2023-06-29

MODEL ORGANISMS HUMANIZED FOR DRUG DISCOVERY AND SCREENING

#10
20230189773
2023-06-22

ENGINEERED CELLS, ANIMAL MODELS, AND USES THEREOF FOR MODELING LOW GRADE GLIOMA (LGG)

#11
20230174978
2023-06-08

METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION

#12
20230054672
2023-02-23

METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION

#13
20220265862
2022-08-25

COMPOSITIONS AND METHODS FOR THE TREATMENT OF LEUKODYSTROPHY AND WHOLE ANIMAL AND CELLULAR MODELS FOR IDENTIFYING EFFICACIOUS AGENTS FOR TREATMENT OF THE SAME

#14
20220256823
2022-08-18

COMPOSITIONS AND METHODS FOR CHARACTERIZING A MICROBIOME

#15
20220167598
2022-06-02

Genetically modified rat models for severe combined immunodeficiency (SCID)

#16
20210392864
2021-12-23

Genetically modified rat models for severe combined immunodeficiency (SCID)

#17
20210337777
2021-11-04

ATOPIC DERMATITIS MODEL NON-HUMAN ANIMAL AND USE THEREOF

#18
20210329894
2021-10-28

METHOD FOR PREPARING ALZHEIMER'S DISEASE (AD) ANIMAL MODEL

#19
20210100227
2021-04-08

loss of function rodent model

#20
20210076649
2021-03-18

Compositions and methods for characterizing a microbiome

#21
20210059229
2021-03-04

ADAM6 KNOCKIN MICE

#22
20210032709
2021-02-04

Mutations in rhodopsin gene in zebrafish and uses thereof

#23
20200107527
2020-04-09

Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy

#24
20200100479
2020-04-02

Recombinant adenovirus-based interferon biotherapeutics in swine

#25
20200053990
2020-02-20

Method of preparing ddx27-deletion zebrafish mutants

#26
20200022343
2020-01-23

Genetically modified mouse expressing human APOE4 and mouse Trem2 p.R47H and methods of use thereof

#27
20190350179
2019-11-21

Parkinson's disease model and methods

#28
20190343969
2019-11-14

Application of GPR45 gene

#29
20190255106
2019-08-22

METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION

#30
20190223416
2019-07-25

CANINE GENOME EDITING

#31
20190191675
2019-06-27

Atopic dermatitis model non-human animal and use thereof

#32
20190024086
2019-01-24

Methods and compositions for modulating gene expression

#33
20180346998
2018-12-06

Mutations in rhodopsin gene in zebrafish and uses thereof

#34
20180295819
2018-10-18

Genetically modified rat models for severe combined immunodeficiency (SCID)

#35
20180282733
2018-10-04

Therapeutic agent for sarcopenia and metabolic diseases

#36
20180271069
2018-09-27

Generation and correction of a humanized mouse model with a deletion of dystrophin exon 44

#37
20180179525
2018-06-28

Methods and compositions for modulating gene expression

#38
20180050097
2018-02-22

IMMUNOTHERAPY COMPOSITIONS AND METHODS FOR TREATMENT OF TAUOPATHY AND TRANSGENIC MOUSE

#39
20180027782
2018-02-01

Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy

#40
20170290309
2017-10-12

Parkinsons disease model and methods

#41
20170258058
2017-09-14

Transgenic pig models of cystic fibrosis

#42
20170251646
2017-09-07

TRANSGENIC PIGS LACKING ONE OR MORE CELLULAR TRANSPORT GENES

#43
20170014476
2017-01-19

SorCS1 for the treatment of obesity

#44
20160345548
2016-12-01

Genetically modified non-human animals and methods relating to innate immune system response detection

#45
20160302397
2016-10-20

GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENCY (SCID)

#46
20160128311
2016-05-12

Screen and use of therapeutics for pancreatic ductal adenocarcinoma

#47
20160058836
2016-03-03

Method for treating arthritis using IK factor or nucleic acid encoding IK factor

#48
20160015778
2016-01-21

SorCS1-like agent for use in the treatment of insulin resistance and diseases related thereto

#49
20150296758
2015-10-22

HUMANIZED TRANSGENIC SINGLE NUCLEOTIDE POLYMORPHISM ANIMAL SYSTEMS

#50
20150296756
2015-10-22

Animal models of neurological disorders

#51
20150105288
2015-04-16

Genetically modified non-human animals and methods relating to innate immune system response detection

#52
20140294798
2014-10-02

RbAp48 transgenic mice for drug discovery in age-related memory decline

#53
20140255975
2014-09-11

Transgenic pig models of cystic fibrosis

#54
20140041062
2014-02-06

Genetically engineered mouse model for autism spectrum disorder having deletion of gene and use thereof

#55
20120304317
2012-11-29

TRANSGENIC RODENT EXPRESSING TRUNCATED DISC1

#56
20120278910
2012-11-01

Transgenic pig in which HO-1 and TNFR1-Fc are simultaneously expressed, and method for producing same

#57
20120207721
2012-08-16

SorCS1 for the treatment of obesity

#58
20120180144
2012-07-12

Animal models of neurological disorders

#59
20120180142
2012-07-12

Cloned transmembrane receptor for 24-hydroxylated vitamin D compounds and uses thereof

#60
20120180141
2012-07-12

Transgenic pig model of cystic fibrosis

#61
20120177577
2012-07-12

Genetically modified rat models for severe combined immunodeficiency (SCID)

#62
20120156183
2012-06-21

SorCS1-like agent for use in the treatment of insulin resistance and diseases related thereto

#63
20110274694
2011-11-10

Erk1/2 posphorylation site specific antibody

#64
20110136892
2011-06-09

Targeting TGF-β as a therapy for Alzheimer's disease

#65
20110097390
2011-04-28

Ultra-small RNAs as toll-like receptor-3 antagonists

#66
20110041193
2011-02-17

NON-HUMAN MAMMAL MODEL OF EPILEPSY

#67
20110030077
2011-02-03

METHODS OF MODULATING THE ORGANIC SOLUTE AND STEROID TRANSPORTER (OSTalpha-OSTbeta) ACTIVITY AND TREATING ASSOCIATED CONDITIONS

#68
20100313286
2010-12-09

G protein-related kinase mutants in essential hypertension

#69
20100269180
2010-10-21

METHODS, COMPOSITIONS AND TRANSGENIC MODELS RELATED TO THE INTERACTION OF T-CADHERIN AND ADIPONECTIN

#70
20090304595
2009-12-10

Transgenic pig model for a hereditary neurodegenerative autosomal dominant disease

#71
20090241203
2009-09-24

Transgenic porcine models of cystic fibrosis

#72
20090235368
2009-09-17

Method of identifying compounds using a transgenic pig model of cystic fibrosis

#73
20090228993
2009-09-10

Transgenic pig with altered incretin function

#74
20050208052
2005-09-22

Use of agonists and antagonists of IL-23 in the treatment of viral infection

#75
20050089871
2005-04-28

G protein-related kinase mutants in essential hypertension