2221 ⎘
Animals characterised by purpose; Animal model, e.g. for test or diseases Animal model for multifactorial diseases
Sub-classes:HIGH EFFICIENCY GENE DELIVERY SYSTEM
#2A RODENT MODEL OF FIBRODYSPLASIA OSSIFICANS PROGRESSIVA
#3HYBRID MICROBEADS WITH BIODEGRADABLE SURFACE AND HETEROGENEOUS SIZE DISTRIBUTION, AND COMPOSITIONS AND METHODS THEREOF
#4THERAPIES WITH LANTHIONINE C-LIKE PROTEIN 2 LIGANDS AND CELLS PREPARED THEREWITH
#5POLY-GLUTAMINE ANDROGEN RECEPTOR KNOCK-IN ANIMAL MODELS, REAGENTS AND METHODS
#6DOWN-REGULATION OF ENDOGENOUS GENES
#7METHOD FOR IDENTIFYING SUBSTANCE CAPABLE OF AFFECTING AGING
#8A NON-HUMAN ANIMAL MAMMALIAN MODEL OF CHRONIC GLAUCOMA
#9NON-HUMAN ANIMAL MODELS FOR AGING AND/OR NEURODEGENERATION
#10ANIMAL MODEL FOR OXIDATIVE STRESS RESEARCH AND USE THEREOF
#11DRUG TARGET OF IDIOPATHIC PULMONARY FIBROSIS
#12ANIMAL MODEL OF IDIOPATHIC PULMONARY FIBROSIS, ITS CONSTRUCTION METHOD AND USE
#13NOVEL METHOD
#14NON-DISRUPTIVE GENE THERAPY FOR THE TREATMENT OF MMA
#15HIGH EFFICIENCY GENE DELIVERY SYSTEM
#16Method for integrating biological tissues with a vascular system
#17Therapies with lanthionine C-like protein 2 ligands and cells prepared therewith
#18Complement Factor H Gene Knockout Rat as a Model of C3 Glomerulopathy
#19NON-HUMAN VERTEBRATE COMPRISING HUMAN LIVER CELLS TRANSPLANTED THEREIN AND METHOD FOR PRODUCING THE SAME
#20NON-HUMAN ANIMALS EXHIBITING DEGENERATIVE SYMPTOM ATTRIBUTED TO PROTEIN AGGREGATION
#21Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
#22METHOD FOR CHANGING CONDITION OF EYELID OF HAIRLESS ANIMAL
#23METHOD AND VECTORS FOR INTRODUCING A GENETIC MUTATION INTO A NON-HUMAN ANIMAL USING A HUMANIZED GENETIC CONSTRUCT
#24Methods of Generating Mature Human Muscle Fibers
#25Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
#26Finding and treatment of inflammation after birth in chimeric animal
#27COMPOSITIONS AND METHODS FOR THE STUDY AND TREATMENT OF ACUTE KIDNEY INJURY
#28HIGH-THROUGHPUT MICROFLUIDIC-BASED METHODS FOR RECORDING DEFECATION MOTOR PROGRAM (DMP) EVENTS IN NEMATODES
#29Preventive or therapeutic agent for kidney disease
#30Animal models of corneal ectatic diseases, methods of producing, and methods of use thereof
#31Urokinase-type plasminogen activator transgenic mouse
#32Anti-aging transgenic Caenorhabditis elegans
#33Therapies with lanthionine C-like protein 2 ligands and cells prepared therewith
#34Methods and compositions for treating metabolic imbalance
#35Transgenic mouse model of retinal vascular disease, method of making, and method of using
#36Animal models for nonalcoholic fatty liver disease
#37NAD BIOSYNTHESIS AND PRECURSORS FOR THE TREATMENT AND PREVENTION OF CANCER AND PROLIFERATION
#38Compositions for use in recovering or ameliorating deterioration of physiological functions due to aging
#39Methods of treating or preventing pruritis by blocking natriuretic polypeptide b
#40Poly-glutamine androgen receptor knock-in mouse models, reagents and methods
#41Non-human primate model of age-related macular degeneration and method for producing same
#42METHOD FOR CHANGING CONDITION OF EYELID OF HAIRLESS ANIMAL
#43Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
#44Mouse with D4R iRNA in the intercalating cell mass of the amygdala
#45ANIMAL MODEL OF NEURONAL INJURY
#46Pharmaceutical composition for treating bone diseases which comprises protein comprising Frizzled 1, Frizzled 2 or Frizzled 7 extracellular cysteine-rich domain
#47Animal models of corneal angiogenesis and corneal ectatic diseases, methods of producing, and methods of use thereof
#48Preventive or therapeutic agent for kidney disease
#49Transgenic mouse expressing kidney-specific human TGF-beta1, and biomarker for tissue fibrosis mouse model
#50Unilateral spinal cord compression
#51Methods of treating or preventing pruritis by blocking natriuretic polypeptide B
#52Transgenic non-human mammal that expresses human MMP2
#53Methods of generating mature human muscle fibers
#54Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
#55COMPOSITIONS AND METHODS FOR THE STUDY AND TREATMENT OF ACUTE KIDNEY INJURY
#56Atopic dermatitis model animal and use thereof
#57ANIMAL MODEL RESISTANT TO HEARING LOSS
#58Fibrotic non-human animal, and use thereof
#59NAD biosynthesis and precursors for the treatment and prevention of cancer and proliferation
#60Animal model of neuronal injury
#61Urokinase-type plasminogen activator transgenic mouse
#62METHOD FOR CHANGING CONDITION OF EYELID OF HAIRLESS ANIMAL
#63Inflammation in vivo model
#64Gut flora-derived extracellular vesicles, and method for searching for a disease model, vaccine, and candidate drug and for diagnosis using the same
#65Compositions and methods for osteogenic gene therapy
#66Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
#67Pharmaceutical composition for treating bone diseases which comprises protein comprising Frizzled1, Frizzled2 or Frizzled7 extracellular cysteine-rich domain
#68MODULATORS OF PROTEASOME ACTIVITY
#69Use of Follistatin-Like Related Gene (FLRG) to Increase Muscle Mass
#70Identification of micro-RNAs involved in neuromuscular synapse maintenance and regeneration
#71METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ATHEROSCLEROSIS
#72TRANSGENIC MICE OVER-EXPRESSING RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCT (RAGE) IN BRAIN AND USES THEREOF
#73Gut flora-derived extracellular vesicles, and method for searching for a disease model, vaccine, and candidate drug and for diagnosis using the same
#74Implantable human liver tissue constructs and uses thereof
#75Novel gene disruptions, compositions and methods relating thereto
#76Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
#77HUMANISED PSORIASIS MODEL
#78TRANSGENIC MOUSE MODEL FOR DEVELOPING ENZYME REPLACEMENT THERAPY FOR IDURONATE-2-SULFATASE DEFICIENCY SYNDROME
#79Targeted and regional cellular ablation in zebrafish
#80CD109 POLYPEPTIDES AND USES THEREOF FOR THE TREATMENT OF SKIN CELLS
#81Immunoadjuvant composition and use thereof
#82Caveolin 1-reporter protein knock-in mouse
#83METHOD OF EXPANDING HUMAN HEPATOCYTES IN VIVO
#84RSPONDIN-3 INHIBITION IN BONE DISORDERS
#85Animal Model for Osteoarthritis and Intervertebral Disc Disease
#86Nurotoxic sterol glycosides
#87Methods for treating osteoporosis with anti-IL-20 receptor antibodies
#88Novel gene disruptions, compositions and methods relating thereto
#89PHARMACEUTICAL COMPOSITION FOR TREATING BONE DISEASES WHICH COMPRISES PROTEIN COMPRISING Frizzled1, Frizzled2 OR Frizzled7 EXTRACELLULAR CYSTEINE-RICH DOMAIN
#90TIKI1 AND TIKI2, WNT INHIBITORS
#91G-Protein Coupled Receptor 30 (GPR30) transgenic animals as a model for cardiovascular diseases
#92CISD2-Knockout Mice and Uses Thereof
#93METHOD OF TREATING HEARING LOSS USING XIAP
#94Modulation of SMRT expression
#95Transgenic mice over-expressing receptor for advanced glycation endproduct (RAGE) in brain and uses thereof
#96Disease animal model for chronic pain
#97Allergic disease model animals
#98CANDIDATE GENES AND BLOOD BIOMARKERS FOR BIPOLAR MOOD DISORDER, ALCOHOLISM AND STRESS DISORDER
#99Therapeutic or prophylactic agent, detection method and detection agent for metabolic syndrome, and method for screening of candidate compound for therapeutic agent for metabolic syndrome
#100GENOMIC EDITING OF GENES INVOLVED IN SECRETASE-ASSOCIATED DISORDERS
#101Compositions and methods for osteogenic gene therapy
#102Biological substance nesfatin and its related substances and uses thereof
#103ESTROGEN RECEPTOR-RELATED RECEPTOR GAMMA (ERR GAMMA) IN BONE AND CARTILAGE FORMATION AND METHODS AND COMPOSITIONS RELATING TO SAME
#104PRODUCTION METHOD OF CYST EXPRESSED TRANSGENIC ANIMAL USING PKD2 GENE
#105COMPOSITIONS AND METHODS FOR MODULATING S-NITROSOGLUTHIONE REDUCTASE
#106Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer and screening methods to identify same
#107Methods of inhibiting photoreceptor apoptosis
#108Targeted and regional cellular ablation in zebrafish
#109Composition and methods for osteogenic gene therapy
#110Inhibitors of PDE4 and Methods of Use
#111SOMATOTRANSGENIC BIOIMAGING
#112Methods of increasing muscle mass using follistatin-like related gene (FLRG)
#113Pig whose genome comprises a heterologous site-specific recombination site and a transpohon tag
#114Method for producing a transgenic pig using a hyper-methylated transposon
#115ANIMAL MODEL, SYSTEM, AND METHOD FOR SCREENING COMPOUNDS FOR ANTITHROMBOTIC AND/OR THROMBOLYTIC ACTIVITY
#116Mouse model for eye disease
#117Compositions and Methods for Modulating Osteoblast Cell Differentiation and Bone Generation Through HIF-1a
#118Nonalcoholic steatohepatitis model rodent and fatty liver model rodent
#119Transgenic pig model for a hereditary neurodegenerative autosomal dominant disease
#120Protein formulations comprising s1-5
#121CISD2-Knockout Mice and Uses Thereof
#122Identification of micro-RNAS involved in neuromuscular synapse maintenance and regeneration
#123Inflammation models in neurodegenerative and arthritic disorders
#124MODEL ANIMAL OF DENDRITIC CELL IMMUNORECEPTOR GENE KNOCKOUT DISEASE
#125Gene disruptions, compositions and methods relating thereto
#126Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
#127TREATMENT OF EPILEPSY BY EXPRESSING ST3GAL-III
#128DNA encoding polypeptide capable of modulating muscle-specific tyrosine kinase activity
#129Reversibly immortalized mammalian liver cells and use thereof
#130Novel Gene Disruptions, Compositions and Methods Relating Thereto
#131CXCL13 Antagonists and Their Use for the Treatment of Inflammatory Diseases
#132ANTIFIBROTIC THERAPY
#133CYR61 COMPOSITIONS AND METHODS
#134PREMATURELY AGEING MOUSE MODELS FOR THE ROLE OF DNA DAMAGE IN AGEING AND INTERVENTION IN AGEING-RELATED PATHOLOGY
#135Oasis gene-deficient mouse
#136Chicken growth differentiation factor-8
#137Diabetes model animal
#138TRANSGENIC TIEG NON-HUMAN ANIMALS
#139Death domain containing receptor 4 antibodies and methods
#140Model of infantile spasm syndrome
#141Growth Differentiation Factor-8
#142Compositions and methods for modulating S-nitrosoglutathione reductase
#143Growth Differentiation Factor-8 Nucleic Acid and Polypeptide from Aquatic Species, and Transgenic Aquatic Species
#144Biological substance nesfatin and its related substances and uses thereof
#145CISD2-Knockout Mice and Uses Thereof
#146Activity-induced pain in animal model of osteoarthritis
#147Animal for Drug Efficacy Evaluation, Method for Developing Chronic Obstructive Pulmonary Disease in Animal for Drug Efficacy Evaluation, and Method for Evaluating Drug Efficacy Using the Animal
#148Human photoaged skin model
#149Combinatorial marking of cells and cell structures with reconstituted fluorescent proteins
#150ISLR gene and its association with osteoarthritis and other bone and cartilage disorders, expression products derived therefrom, and uses thereof
#151O-GLYCANS IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND CANCERS
#152Methods and compositions for modulating gamete adhesion
#153Human photoaged skin model
#154Methods and compositions for inhibition of immune responses
#155Method of use of specific natriuretic peptide receptor c ligands, transgenic non-human mammals expressing specific natriuretic peptide receptor c antagonists and cells thereof
#156BMP pathway methods and compositions
#157Cytoplasmic dynein heavy chain 1 genes, expression products, non-human animal model uses in human neurological diseases
#158Human skin equivalents expressing exogenous polypeptides
#159Ha4,a new osteoblast-and chondrocyte-specific small secreted peptide, compositions and methods of use
#160Inducible plasmid vector encoding TGF-β and use thereof
#161In vivo assay for neurite outgrowth in zebrafish and its application in drug screening
#162Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
#163Methods of screening agents for activity using teleosts
#164Hepatic cirrhosis model animal and method of constructing the same
#165Transgenic TIEG non-human animals
#166Methods and agents for maintaining muscle mass and for preventing muscle atrophy and biomarkers for monitoring same
#167CARD-4 molecules and uses thereof
#168BMP pathway methods and compositions
#169Growth differentiation factor-8 nucleic acid and polypeptide from aquatic species, and transgenic aquatic species
#170SIRT6 transgenic non-human animals and assay methods
#171Modulators of dimethylarginine dimethylaminohydrolase and methods of use thereof
#172Methods of screening agents for activity using teleosts
#173Polynucleotides encoding growth differentiation factor-8
#174Assay for toxin induced neuronal degeneration and viability in
#175Compositions, methods and kits relating to CTHRC1, a novel modulator of collagen matrix
#176Isle gene and its association with osteoarthritis and other bone and cartilage disorders expression products derived therefrom and uses thereof
#177Methods and products for identifying modulators of P2X7 receptor activity, and their use in the treatment of skeletal disorders
#178Compositions and methods for modulating S-nitrosoglutathione reductase