2226 ⎘
Animals characterised by purpose; Animal model, e.g. for test or diseases; Animal model for multifactorial diseases Animal model for diseases of the hematopoietic system
Genetically Modified Mice and Engraftment
#2Genetically Modified Non-Human Animals And Methods Of Use Thereof
#3GENE THERAPY OF HEMOPHILIA A USING VIRAL VECTORS ENCODING RECOMBINANT FVIII VARIANTS WITH INCREASED EXPRESSION
#4NON-HUMAN ANIMALS HAVING A HUMANIZED B-CELL ACTIVATING FACTOR GENE
#5HUMAN LAMBDA LIGHT CHAIN MICE
#6Methods for Treating and/or Preventing Graft-Versus-Host Disease and/or Diffuse Alveolar Hemorrhage and/or Veno-Occlusive Disease Associated with Hematopoietic Stem Cell Transplant
#7T CELL REGULATION
#8NON-HUMAN ANIMALS HAVING A HUMANIZED CLUSTER OF DIFFERENTIATION 47 GENE
#9TELOMERASE REVERSE TRANSCRIPTASE-BASED THERAPIES
#10GENETICALLY MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO
#11Genetically Modified Non-Human Animals and Methods of Use Thereof
#12Gene therapy of hemophilia a using viral vectors encoding recombinant FVIII variants with increased expression
#13MODELING ONCOLOGY ON DEMAND
#14SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS
#15Genetically Modified Mice and Engraftment
#16Genetically modified non-human animals and methods of use thereof
#17Mouse having a humanized B-cell activating factor gene
#18Targeted modification of rat genome
#19HUMAN ARTIFICIAL CHROMOSOME CONTAINING HUMAN ANTIBODY LAMBDA LIGHT CHAIN GENE AND NON-HUMAN ANIMAL CONTAINING THE HUMAN ARTIFICIAL CHROMOSOME CAPABLE OF GENETIC TRANSMISSION
#20Methods for treating and/or preventing graft-versus-host disease and/or diffuse alveolar hemorrhage and/or veno-occlusive disease associated with hematopoietic stem cell transplant
#21TELOMERASE REVERSE TRANSCRIPTASE-BASED THERAPIES
#22Non-human animals having a humanized signal-regulatory protein gene
#23T CELL REGULATION
#24Mouse having a humanized cluster of differentiation 47 gene
#25PRODUCTION AND USE OF RED BLOOD CELLS
#26MRGPRX2/MRGPRB2 EXPRESSING CELL BASED ASSAY TO DETECT PSEUDO-ALLERGIC DRUG REACTIONS AND TO IDENTIFY BLOCKERS TO PREVENT THE ADVERSE REACTIONS
#27HUMAN LAMBDA LIGHT CHAIN MICE
#28HUMAN ARTIFICIAL CHROMOSOME CONTAINING HUMAN ANTIBODY LAMBDA LIGHT CHAIN GENE AND NON-HUMAN ANIMAL CONTAINING THE HUMAN ARTIFICIAL CHROMOSOME CAPABLE OF GENETIC TRANSMISSION
#29SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS
#30Non-human animals having a humanized signal-regulatory protein gene
#31Genetically modified non-human animals and methods of use thereof
#32Genetically modified non-human animals expressing human EPO
#33METHODS OF A DROSOPHILA MODEL FOR CHRONIC MYELOID LEUKEMIA (CML) TREATMENT
#34Targeted modification of rat genome
#35Genetically modified mice and engraftment
#36Non-human animals having a disruption in a C9ORF72 locus
#37HUMAN LAMBDA LIGHT CHAIN MICE
#38Modulation of BCL11A for treatment of hemoglobinopathies
#39HUMAN LAMBDA LIGHT CHAIN MICE
#40Adeno-associated virus compositions for restoring HBB gene function and methods of use thereof
#41Methods for treating and/or preventing graft-versus-host disease and/or diffuse alveolar hemorrhage and/or veno-occlusive disease associated with hematopoietic stem cell transplant
#42Non-human animals having a humanized B-cell activating factor gene
#43Non-human animals having a humanized signal-regulatory protein gene
#44Genetically modified non-human animals and methods of use thereof
#45USE OF MAPK INHIBITORS TO REDUCE LOSS OF HEMATOPOIETIC STEM CELLS DURING EX VIVO CULTURE AND/OR GENETIC MANIPULATION
#46Mice with a modified glucose-6-phosphate dehydrogenase gene
#47Mouse lymphoma cell line and animal model of human high grade B-cell lymphoma
#48Methods of increasing T cell immune response in the treatment of cancer
#49Method of using mouse having a humanized cluster of differentiation 47 gene
#50SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS
#51Modulation of BCL11A for treatment of hemoglobinopathies
#52Production and use of red blood cells
#53Transgenic Immunodeficient Mouse Expressing Human SIRP-alpha
#54Non-human animals having a humanized signal-regulatory protein gene
#55Human lambda light chain mice
#56Genetically Modified Non-Human Animals And Methods Of Use Thereof
#57Compositions and Methods for Increasing Red Blood Cells
#58Non-human animals having a humanized signal-regulatory protein gene
#59Telomerase reverse transcriptase-based therapies
#60Targeted modification of rat genome
#61MrgprX2/MrgprB2 expressing cell based assay to detect pseudo-allergic drug reactions and to identify blockers to prevent the adverse reactions
#62MODELS OF THROMBOTIC THROMBOCYTOPENIC PURPURA AND METHODS OF USE THEREOF
#63Non-human animals having a humanized B-cell activating factor gene
#64Genetically modified mice and engraftment
#65Modulation of BCL11A for treatment of hemoglobinopathies
#66Human lambda light chain mice
#67Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#68Human SIRPα transgenic mice and their methods of use
#69Non-human animals having a humanized signal-regulatory protein gene
#70Methods for testing anti-thrombotic agents
#71Non-human animals having a disruption in a C9ORF72 locus
#72Mammalian gene modification method using electroporation
#73Non-human animals having a humanized cluster of differentiation 47 gene
#74Methods for treatment comprising an antibody that binds CD223 protein
#75Human lambda light chain mice
#76Human lambda light chain mice
#77Non-human animals having a humanized signal-regulatory protein gene
#78Hybrid light chain mice
#79Genetically modified non-human animals expressing human EPO
#80Genetically modified non-human animals and methods of use thereof
#81Compositions and Methods of Treatment of Black Hemophiliac Patients
#82Use of RET agonist molecules for haematopoietic stem cell expansion protocols and transplantation therapy and a RET agonist kit
#83Method of cloning a lambda light chain variable domain using a human lambda light chain mouse
#84Method of making antibodies using a human lambda light chain mouse
#85Method of making antibodies using a human lambda light chain mouse
#86Non-human animals having a humanized B-cell activating factor gene
#87Human lambda light chain mice
#88Non-human animals having a humanized signal-regulatory protein gene
#89Non-human animals having a humanized signal-regulatory protein gene
#90Transgenic immunodeficient mouse expressing human SIRP-alpha
#91Delivery methods and compositions for nuclease-mediated genome engineering
#92Production and use of red blood cells
#93Hybrid light chain mice
#94Genetically modified mice and engraftment
#95Epo knockout GFP anemic mouse
#96Human SIRPAalpha transgenic animals and their methods of use
#97Human lambda light chain mice
#98Human lambda light chain mice
#99Hairless NOD scid mouse
#100Modulation of BCL11A for treatment of hemoglobinopathies
#101Method for treating cancer with an antibody to CD223 protein
#102Methods for inhibiting hematopoiesis with a hedgehog antagonist
#103Methods of Modulating Thrombocytopenia and Modified Transgenic Pigs
#104Genetically modified mice and engraftment
#105Genetically modified mice and engraftment
#106Non-Human Mammal Model Of Human Hematopoietic Cancer
#107SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS
#108Methods Of Producing Humanized Non-Human Mammals
#109FUNCTIONAL DISRUPTION OF AN IMMUNOGLOBULIN GENE IN AN AVIAN EMBRYONIC STEM CELL
#110Isolation and growth of stem cells from hemangiomas
#111Hybrid light chain mice
#112Human lambda light chain mice
#113Immunoadjuvant composition and use thereof
#114TARGETING OF SALL4 FOR THE TREATMENT AND DIAGNOSIS OF PROLIFERATIVE DISORDERS ASSOCIATED WITH MYELODYSPLASTIC SYNDROME (MDS)
#115CALCIUM SENSOR STIM1 AND THE PLATELET SOC CHANNEL ORAI1 (CRACM1) ARE ESSENTIAL FOR PATHOLOGICAL THROMBUS FORMATION
#116Human CTLA-4 antibodies and their uses
#117MODELS OF ERYTHROPOIESIS
#118Genetically modified mice and engraftment
#119Modulation of BCL11A for treatment of hemoglobinopathies
#120SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS
#121METHODS OF USING FLT3-LIGAND IN THE TREATMENT OF CANCER
#122Functional Disruption Of Avian Immunoglobulin Genes
#123METHODS OF TREATMENT USING IL-17E ANTAGONISTS
#124COMPOSITIONS AND METHODS FOR HEMATOPOIETIC STEM CELL EXPANSION OR FOR MODULATING ANGIOGENESIS
#125IL-21 RECEPTOR KNOCKOUT ANIMAL AND METHODS OF USE THEREOF
#126Anti-cancer vaccine composition comprising an anti-CD223 antibody and kit comprising an anti-cancer vaccine and an anti-CD223 antibody
#127Nonhuman model animal lacking the ability to control lymphocyte migration
#128Models of thrombotic thrombocytopenic purpura and methods of use thereof
#129Human CTLA-4 antibodies and their uses
#130METHODS FOR MANIPULATING STEM CELLS
#131Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
#132METHODS AND COMPOSITIONS FOR MODULATION OF STEM CELL AGING
#133MODEL ANIMAL OF DENDRITIC CELL IMMUNORECEPTOR GENE KNOCKOUT DISEASE
#134METHODS FOR TESTING ANTI-THROMBOTIC AGENTS
#135Model System for TCR (ZETA) Chain Downregulation
#136BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
#137Targeting constructs for the functional disruption of avian immunoglobulin genes
#138Methods to Treat or Prevent Viral-Associated Lymphoproliferative Disorders
#139Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#140ISOLATION AND GROWTH OF STEM CELLS FROM HEMANGIOMAS
#141Targeting of sall4 for the treatment and diagnosis of proliferative disorders associated with myelodysplastic syndrome (MDS)
#142Animal model for the human immune system, and method for producing the same
#143Nonhuman model animal lacking the ability to control lymphocyte migration
#144IL-21 AS A REGULATOR OF IMMUNOGLOBIN PRODUCTION
#145Nonhuman model animal lacking the ability to control lymphocyte migration
#146Nonhuman model animal of Th2-mediated hyperimmune response
#147Method for rendering a system immunologically compatible utilizing a nucleic acid construct, a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene and an immunologically compatible system containing a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene
#148Methods of Identifying Compounds Which Modulate Granulocite-Colony Stimulating Factor (G-Csf) Dependent Processes by Modulation of the Levels of Suppressor of Cytokine Signaling (Socs)
#149Cloning B and T lymphocytes
#150Tolerance to Graft Prior to Thymic Reactivation
#151Use of Caspase-8 Inhibitors for Modulating Hematopoiesis
#152Cell and transgenic animal modelling human antigenic presentation and their uses
#153Methods of using flt3-ligand in the treatment of cancer
#154Targeting of SALL4 for the treatment and diagnosis of proliferative disorders associated with myelodysplastic syndrome (MDS)
#155IL-17 like molecules and uses thereof
#156Oncohumouse
#157Transgenic mouse expressing a polynucleotide encoding human tissue factor
#158Therapeutiv preparation for hematopoietic disease
#159Delivery vehicle for recombinant proteins
#160Transgenic non-human Act1-deficient mammals and uses thereof
#161Proliferator-Activated Receptor Disruptions, Compositions and Methods Relating Thereto
#162Novel haemopoietin receptor and genetic sequences encoding same
#163T cell regulation
#164Transgenic mice expressing human CD20 and/or CD16
#165Transgenic mice expressing human cd20
#166Artificial human chromosome containing human antibody a light chain gene
#167Transgenic non-human mammals as models for human pathologies of stem cell origin
#168Method of screening candidate drugs for the treatment of leukemia
#169Transgenic non-human mammals as models for human pathologies of stem cell origin
#170Transgenic non-human mammals as models for human pathologies of stem cell origin
#171Method for rendering a system immunologically compatible utilizing a nucleic acid construct, a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene and an immunologically compatible system containing a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene
#172Inhibition of B-cell maturation and antibody production
#173Induction of methylation of CpG sequences by dsRNAS in mammalian cells
#174Human antibodies derived from immunized xenomice
#175Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#176BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
#177Modulation of an innate immune response by altering TRIAL-R signaling
#178Human CTLA-4 antibodies and their uses
#179Transgenic zebra fish embryo model for hematopoiesis and lymphoproliferative disorders
#180IL-21 as a regulator of immunoglobin production
#181Expressed ligand-vascular intercellular signaling molecule
#182Eosinophil-deficient transgenic animals
#183Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
#184Aiolos, Helios, Daedalos and Ikaros: genes, polypeptides, regulatory elements and uses thereof
#185Compositions and methods for the treatment and diagnosis of immune disorders
#186Non-human transgenic mammals used as models for human pathologies originating from stem cells
#187Expressed ligand-vascular intercellular signaling molecule
#188Nonhuman model animal of Th2-mediated hyperimmune response
#189Generation of xenogeneic antibodies
#190Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects
#191IL-17 like molecules and uses thereof
#192Nonhuman model animal lacking the ability to control lymphocyte migration
#193Cell and transgenic animal modelling human antigenic presentation and their uses
#194Use of ephrins and related molecules to regulate cellular proliferation
#195Il-17 like molecules and uses thereof
#196IL-17 like molecules and uses thereof
#197Methods for modulating hematopoiesis and vascular growth