ClassID:

20314

A61K31/4025 - page 2 - CPC Classification

Classification description:

Medicinal preparations containing organic active ingredients; Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim

Recent Application in this class:
#301
20220211665
2022-07-07

PYRROLE AMIDE COMPOUND AND USE THEREOF

#302
20220211664
2022-07-07

LYMPH DIRECTING PRODRUGS

#303
20220193088
2022-06-23

Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids

#304
20220184035
2022-06-16

HBV inhibitor and its use

#305
20220175750
2022-06-09

SUSTAINED RELEASE FORMULATION FOR LOCAL DELIVERY OF CDK9 INHIBITORS

#306
20220168273
2022-06-02

Pharmaceutical combination for the treatment of cancer

#307
20220160711
2022-05-26

METHODS OF TREATING OR PREVENTING PRETERM LABOR

#308
20220142981
2022-05-12

APREMILAST LIPOPHILIC TOPICAL PHARMACEUTICAL COMPOSITIONS

#309
20220133693
2022-05-05

Therapeutic treatment of microsatellite unstable cancers

#310
20220127240
2022-04-28

Prodrugs of urolithins and uses thereof

#311
20220126039
2022-04-28

INTRANASAL DESMOPRESSIN ADMINISTRATION

#312
20220125754
2022-04-28

TREATING THE CAUSATIVE AGENT IN ADHESIOGENESIS

#313
20220118085
2022-04-21

USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE

#314
20220105105
2022-04-07

NT5C2 INHIBITORS FOR THE TREATMENT OF CHEMOTHERAPY-RESISTANT ACUTE LYMPHOBLASTIC LEUKEMIA

#315
20220099685
2022-03-31

METHOD

#316
20220096437
2022-03-31

ANTIBACTERIAL COMPOUNDS

#317
20220088033
2022-03-24

METHODS FOR TREATING OR PREVENTING CANCER IN A KRAS-VARIANT PATIENT AND FOR DIAGNOSING RISK OF DEVELOPING MULTIPLE PRIMARY BREAST TUMORS

#318
20220087989
2022-03-24

ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF SKIN CANCERS

#319
20220081439
2022-03-17

HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF

#320
20220071965
2022-03-10

Pharmaceutical compositions and methods comprising a combination of a benzoxazole transthyretin stabilizer and an additional therapeutic agent

#321
20220071957
2022-03-10

Pyrrole compounds

#322
20220062254
2022-03-03

INHIBITORS OF GANGLIOSIDES METABOLISM FOR THE TREATMENT OF MOTOR NEURON DISEASES

#323
20220062230
2022-03-03

Substituted benzothiophene analogs as selective estrogen receptor degraders

#324
20220062194
2022-03-03

Treatment of Addiction and Impulse-Control Disorders Using PDE7 Inhibitors

#325
20220054454
2022-02-24

CASPASE-1 INHIBITION AND USES THEREOF FOR PREVENTION AND TREATMENT OF NEUROLOGICAL CONDITIONS

#326
20220048881
2022-02-17

TRICYCLIC SPIRO COMPOUND

#327
20220040149
2022-02-10

Combination therapies using immuno-dash inhibitors and PGE2 antagonists

#328
20220031815
2022-02-03

ANIMAL FEED COMPOSITION AND USE THEREOF

#329
20220023263
2022-01-27

Compounds for the treatment of cancers associated with human papillomavirus

#330
20220023262
2022-01-27

Composition comprising high purity pyrrole derivative and method for preparation thereof

#331
20220023261
2022-01-27

Pharmaceutical combinations for the treatment of cancer

#332
20220017559
2022-01-20

CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS

#333
20210395265
2021-12-23

Anti-cancer agents and preparation thereof

#334
20210393590
2021-12-23

INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE

#335
20210393589
2021-12-23

Pharmaceutical combination for the treatment of melanoma

#336
20210393583
2021-12-23

Method for the treatment of pancreatitis

#337
20210386721
2021-12-16

SUBSTITUTED PHENYLPROPENYL PYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL APPLICATIONS

#338
20210386708
2021-12-16

Sulcardine administration for treatment of acute atrial fibrillation

#339
20210378989
2021-12-09

ESKETAMINE FOR USE IN TREATING MAJOR DEPRESSIVE DISORDER

#340
20210371401
2021-12-02

Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine

#341
20210369672
2021-12-02

INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE

#342
20210353593
2021-11-18

METHODS OF TREATING IGA NEPHROPATHY WITH ATRASENTAN

#343
20210338839
2021-11-04

COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY

#344
20210330678
2021-10-28

PAPD5 INHIBITORS AND METHODS OF USE THEREOF

#345
20210330677
2021-10-28

PKC INHIBITORS FOR THE TREATMENT OF SEPTIC CHOLESTASIS WITH CTM TARGETING

#346
20210330633
2021-10-28

METHODS FOR TREATING GAUCHER DISEASE

#347
20210322743
2021-10-21

MICRONEEDLE ARRAY PATCH FOR DRUG DELIVERY AND PRODUCTION METHOD THEREOF

#348
20210322545
2021-10-21

SMC COMBINATION THERAPY FOR THE TREATMENT OF CANCER

#349
20210309731
2021-10-07

Composition of a drug carrier, pharmaceutical composition thereof, preparation method and use method thereof

#350
20210299139
2021-09-30

Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids

#351
20210299100
2021-09-30

Biaryl derivatives as YAP/TAZ-TEAD protein-protein interaction inhibitors

#352
20210299098
2021-09-30

SELECTIVE ESTROGEN RECEPTOR MODULATOR FOR TREATMENT OF PANCREATIC CANCER

#353
20210285000
2021-09-16

COMBINATION THERAPY FOR TREATING HEPATITIS B VIRUS INFECTION

#354
20210283104
2021-09-16

Pharmaceutical combinations for the treatment of cancer

#355
20210275657
2021-09-09

NEOANTIGENS AND USES THEREOF

#356
20210275636
2021-09-09

Compositions containing exosome carrying NF-κB inhibitors and methods of using thereof

#357
20210275497
2021-09-09

MACROGOL 15 HYDROXYSTEARATE FORMULATIONS

#358
20210267996
2021-09-02

Compounds for inhibition of inflammation

#359
20210267951
2021-09-02

COMBINATION THERAPY FOR PULMONARY HYPERTENSION

#360
20210261516
2021-08-26

MYC G-QUADRUPLEX STABILIZING SMALL MOLECULES AND THEIR USE

#361
20210247406
2021-08-12

Method and compositions for the treatment and detection of endothelin-1 related kidney diseases

#362
20210236632
2021-08-05

Use of toll-like receptor 2 (TLR-2) agonist for modulating human immune response

#363
20210236476
2021-08-05

METHODS OF TREATING CANCER WITH SMALL MOLECULE PD-L1 INHIBITORS

#364
20210228732
2021-07-29

Antibodies, pharmaceutical compositions and methods

#365
20210228489
2021-07-29

COMPOSITIONS FOR TREATING CYSTIC FIBROSIS

#366
20210220340
2021-07-22

COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASE

#367
20210220328
2021-07-22

PYRROLE DERIVATIVES AS ACC INHIBITORS

#368
20210214448
2021-07-15

CCR5 BINDING AGENT FOR THE TREATMENT OF CCR5 POSITIVE METASTATIC CANCER

#369
20210213005
2021-07-15

Pyrrolidine glycosidase inhibitors

#370
20210198233
2021-07-01

Thiophene derivatives

#371
20210196730
2021-07-01

COMPOUND AND USE THEREOF

#372
20210196680
2021-07-01

SYNERGISTIC PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK

#373
20210188758
2021-06-24

Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists

#374
20210186982
2021-06-24

METHODS AND COMPOSITIONS FOR TREATING MELANOMA

#375
20210186932
2021-06-24

Treatment of ER-negative breast cancer with an PDGF-CC inhibitor and anti-estrogen

#376
20210177827
2021-06-17

PAPD5 inhibitors and methods of use thereof

#377
20210177821
2021-06-17

Androgen Receptor Modulator And Uses Thereof

#378
20210177811
2021-06-17

Use of NOX inhibitors for treatment of cancer

#379
20210171507
2021-06-10

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INHIBITORS

#380
20210169838
2021-06-10

Novel class of compounds for the treatment of cardiovascular disease.

#381
20210161909
2021-06-03

COMBINATION THERAPY

#382
20210147403
2021-05-20

SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES

#383
20210147386
2021-05-20

Pyrrolidine and piperidine compounds

#384
20210137887
2021-05-13

READY-TO-USE, TERMINALLY STERILE PACKAGING FOR SURGICAL ANTISEPTIC AND METHOD OF USE

#385
20210137884
2021-05-13

Inhibitors of metallo-beta-lactamases

#386
20210130867
2021-05-06

NOVEL KINASE FOR TREATING AND PREVENTING FUNGAL INFECTIONS, AND USE THEREOF

#387
20210128674
2021-05-06

LHRH-CONJUGATED PRODIGIOSIN AND USES THEREOF

#388
20210128578
2021-05-06

CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE

#389
20210121465
2021-04-29

Ferrochelatase inhibitors and methods of use

#390
20210102215
2021-04-08

TREATMENT AND PREVENTION OF VIRAL INFECTION

#391
20210100800
2021-04-08

Use of a combinational therapy of LSD1 inhibitors with P21 activators in the treatment of cancer

#392
20210093633
2021-04-01

TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY

#393
20210077453
2021-03-18

Inhibitors of glucosylceramide degradation in the treatment of diseases of the motor units

#394
20210072261
2021-03-11

Method and compositions for the treatment and detection of endothelin-1 related kidney diseases

#395
20210040148
2021-02-11

Therapeutics for the treatment of glaucoma

#396
20210038568
2021-02-11

Sulcardine salts

#397
20210017131
2021-01-21

P2RX7 modulators in therapy

#398
20210015793
2021-01-21

COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES

#399
20210008232
2021-01-14

Chemical conjugates of Evans Blue derivatives and their use as radiotherapy and imaging agents for targeting prostate cancer

#400
20200397804
2020-12-24

TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISORDERS

#401
20200390774
2020-12-17

TRPA1 ANTAGONISTS FOR USE IN THE TREATMENT OF ATOPIC DERMATITIS

#402
20200385473
2020-12-10

Anti-C10orf54 antibodies and uses thereof

#403
20200383988
2020-12-10

Compounds

#404
20200383948
2020-12-10

Pharmaceutical combinations for the treatment of cancer

#405
20200377888
2020-12-03

RUNX1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition

#406
20200375946
2020-12-03

Inhibitors of metallo-beta-lactamases

#407
20200360411
2020-11-19

Repurposcins: targeted inhibitors of mitochondrial biogenesis for eradicating cancer stem cells

#408
20200360362
2020-11-19

Sustained-release triptan compositions and method of use the same through subdermal route or the like

#409
20200352956
2020-11-12

Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids

#410
20200347043
2020-11-05

MODULATORS OF THE INTEGRATED STRESS PATHWAY

#411
20200345693
2020-11-05

Thioindirubins

#412
20200323839
2020-10-15

METHODS AND COMPOSITIONS FOR TREATMENT OF DISORDERS AMELIORATED BY MUSCARINIC RECEPTOR ACTIVATION

#413
20200323821
2020-10-15

Pyrrole compounds

#414
20200317714
2020-10-08

Cyclic peroxides as prodrugs for selective delivery of agents

#415
20200317666
2020-10-08

Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof

#416
20200316049
2020-10-08

Methods and compositions for treatment of endothelin B receptor expressing tumors

#417
20200316046
2020-10-08

NANOPARTICLE COMPOSITIONS OF ENDOTHELIN B RECEPTOR ANTAGONISTS

#418
20200316025
2020-10-08

Stable amorphous Eliglustat premix and process for the preparation thereof

#419
20200316024
2020-10-08

Sulcardine salts

#420
20200308128
2020-10-01

MYC G-quadruplex stabilizing small molecules and their use

#421
20200306225
2020-10-01

STABLE N-((1R,2R)-1-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-1-HYDROXY-3-(PYRROLIDIN-1-YL)PROPAN-2-YL) OCTANAMIDE (2R,3R)-2,3-DIHYDROXYSUCCINATE PREMIX AND PROCESS FOR PREPARATION THEREOF

#422
20200297797
2020-09-24

Enteric combination therapy

#423
20200289667
2020-09-17

Targeting Macrophages to Modulate Electrical Conduction in the Heart

#424
20200289506
2020-09-17

COMBINATION OF A BTK INHIBITOR AND AN INHIBITOR OR CDK9 TO TREAT CANCER

#425
20200289495
2020-09-17

METHODS OF INHIBITING ENDOTHELIN B RECEPTOR EXPRESSING TUMOR METASTASES

#426
20200289465
2020-09-17

Compounds for the treatment of cancers associated with human papillomavirus

#427
20200289464
2020-09-17

Benzofuran derivatives and their use as bromodomain inhibitors

#428
20200276204
2020-09-03

COMBINATION THERAPY FOR IMMUNOLOGICAL DISEASES

#429
20200268753
2020-08-27

PERK AND IRE-1A INHIBITORS AGAINST NEURODEVELOPMENTAL DISORDERS

#430
20200262836
2020-08-20

Inhibitors of hepatitis C virus replication

#431
20200261426
2020-08-20

Oral solid dosage form composition having improved disintegration and preparation method therefor

#432
20200261411
2020-08-20

TRPV4 antagonists

#433
20200255410
2020-08-13

Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same

#434
20200254050
2020-08-13

STABLE COMPOSITIONS OF NEUROACTIVE PEPTIDES

#435
20200253930
2020-08-13

3-(5-fluoroindolyl)-4-arylmaleimide compounds and their use in tumor treatment

#436
20200246471
2020-08-06

Polymer derivatives having particular atom arrangements

#437
20200246292
2020-08-06

PHARMACEUTICAL COMPOSITIONS AND THE TREATMENT OF OVERACTIVE BLADDER

#438
20200237864
2020-07-30

METHODS AND COMPOSITIONS FOR TREATING FIBROTIC INTERSTITIAL LUNG DISEASE

#439
20200223838
2020-07-16

METHODS OF USE OF PHENOXYPROPYLAMINE COMPOUNDS TO TREAT DEPRESSION

#440
20200223813
2020-07-16

Prodrugs of urolithins and uses thereof

#441
20200222310
2020-07-16

PHARMACEUTICAL COMPOSITION COMPRISING ELIGLUSTAT

#442
20200216406
2020-07-09

Benzothiophene estrogen receptor modulators

#443
20200215073
2020-07-09

Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists

#444
20200207740
2020-07-02

Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine

#445
20200207709
2020-07-02

Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions

#446
20200199689
2020-06-25

Method for Predicting Effectiveness of Angiogenesis Inhibitor

#447
20200197407
2020-06-25

Targeting kinases for the treatment of cancer metastasis

#448
20200197366
2020-06-25

PHARMACEUTICAL COMPOSITION COMPRISING ELIGLUSTAT

#449
20200197365
2020-06-25

TREATMENT WITH NMDA RECEPTOR MODULATORS

#450
20200190019
2020-06-18

PPAR agonists

#451
20200188419
2020-06-18

COMBINATION FORMULATION OF TWO ANTIVIRAL COMPOUNDS

#452
20200188357
2020-06-18

Sulcardine administration for treatment of acute atrial fibrillation

#453
20200179340
2020-06-11

Antifungal agents

#454
20200179339
2020-06-11

PHARMACEUTICALS COMPOSITIONS FOR TREATMENT OF ATOPIC DERMATITIS

#455
20200155502
2020-05-21

Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiotherapy

#456
20200138807
2020-05-07

Tyrosine kinase inhibitors regenerate non-cancerous tissue after cancer therapy

#457
20200138804
2020-05-07

METHODS FOR TREATING CANCER

#458
20200138782
2020-05-07

Pharmaceutical combination for the treatment of cancer

#459
20200121683
2020-04-23

Methods of treating or preventing preterm labor

#460
20200121645
2020-04-23

COMPOSITION FOR PREVENTING OR TREATING EGFR-MUTANT NON-SMALL CELL LUNG CANCER

#461
20200115339
2020-04-16

EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF

#462
20200102565
2020-04-02

Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer

#463
20200102294
2020-04-02

Compositions and methods for treating neurodegenerative diseases

#464
20200102284
2020-04-02

Tricyclic spiro compound

#465
20200095217
2020-03-26

HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE

#466
20200093832
2020-03-26

Methods and compositions for the inhibition of PIN1

#467
20200093794
2020-03-26

Methods, agents, and compositions for the treatment of acute myeloid leukemia

#468
20200079754
2020-03-12

INHIBITORS OF BRUTONS TYROSINE KINASE

#469
20200078542
2020-03-12

INTRANASAL DESMOPRESSIN ADMINISTRATION

#470
20200078376
2020-03-12

Inhibiting senescent processes in beta cells for the prevention of type 1 diabetes

#471
20200078353
2020-03-12

OLIGOMER-OPIOID AGONIST CONJUGATES

#472
20200069703
2020-03-05

CHEMICAL ENTITIES THAT KILL SENESCENT CELLS FOR USE IN TREATING AGE-RELATED DISEASE

#473
20200069658
2020-03-05

COMBINATION THERAPY FOR PULMONARY HYPERTENSION

#474
20200039964
2020-02-06

Citric acid derivative

#475
20200031806
2020-01-30

Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same

#476
20200030280
2020-01-30

Andrographolide derivatives and method of using the same for treatment or prevention of fibrosis

#477
20200022956
2020-01-23

Combination therapies using immuno-dash inhibitors and PGE2 antagonists

#478
20190389799
2019-12-26

Type III deiodinase inhibitors and uses thereof

#479
20190388457
2019-12-26

Prognostic methods and systems of treatment for acute lymphoblastic leukemia

#480
20190388392
2019-12-26

Oral eliglustat transmucosal delivery system

#481
20190374507
2019-12-12

Compositions and methods of treating cardiac hypertrophy and heart failure

#482
20190365683
2019-12-05

Pharmaceutical compositions and the treatment of overactive bladder

#483
20190359585
2019-11-28

SYNTHESIS OF RESORCYLIC ACID LACTONES USEFUL AS THERAPEUTIC AGENTS

#484
20190358202
2019-11-28

Aptamer-drug conjugate and use thereof

#485
20190358201
2019-11-28

MODIFIED DOXORUBICIN COMPOSITIONS AND METHODS

#486
20190350913
2019-11-21

Inhibitors of gangliosides metabolism for the treatment of motor neuron diseases

#487
20190350902
2019-11-21

Neuroprotective compounds and methods of use

#488
20190350878
2019-11-21

Telomerase activating compounds for use in fertility and related applications

#489
20190343802
2019-11-14

Cell-protective compounds and their use

#490
20190330201
2019-10-31

Aryl hydrocarbon receptor modulators

#491
20190328709
2019-10-31

Caspase-1 inhibition and uses thereof for prevention and treatment of neurological conditions

#492
20190322649
2019-10-24

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INHIBITORS

#493
20190321355
2019-10-24

TREATMENT OF MENTAL, MOVEMENT AND BEHAVIORAL DISORDERS

#494
20190314334
2019-10-17

COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASES

#495
20190314333
2019-10-17

Antifungal agents

#496
20190314330
2019-10-17

IRE-1α inhibitors

#497
20190307770
2019-10-10

METHODS FOR TREATING OR PREVENTING CANCER IN A KRAS-VARIANT PATIENT AND FOR DIAGNOSING RISK OF DEVELOPING MULTIPLE PRIMARY BREAST TUMORS

#498
20190307739
2019-10-10

Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation

#499
20190290722
2019-09-26

TWO PART FORMULATION SYSTEM FOR OPHTHALMIC DELIVERY

#500
20190290632
2019-09-26

Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy

#501
20190284224
2019-09-19

Cyclic peroxides as prodrugs for selective delivery of agents

#502
20190284222
2019-09-19

Anticancer compounds

#503
20190283010
2019-09-19

EX VIVO METHODS FOR PREDICTING AND CONFIRMING IN VIVO METABOLISM OF PHARMACEUTICALLY ACTIVE COMPOUNDS

#504
20190282544
2019-09-19

PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF MELANOMA

#505
20190282521
2019-09-19

Compounds for use in treatment of mucositis

#506
20190275004
2019-09-12

PHARMACEUTICAL COMBINATIONS FOR THE TREATMENT OF CANCER

#507
20190269652
2019-09-05

N-methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)-2-aminophenylacetamide derivatives agonists for the κ opioid receptor

#508
20190263795
2019-08-29

Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases

#509
20190247388
2019-08-15

OLIGOMER-OPIOID AGONIST CONJUGATES

#510
20190231790
2019-08-01

USE OF PARTHENOLIDE DERIVATIVES AS ANTILEUKEMIC AND CYTOTOXIC AGENTS

#511
20190231745
2019-08-01

INHIBITORS OF T CELL RECEPTOR AND USES THEREOF

#512
20190224131
2019-07-25

DELAYED-RELEASE FORMULATIONS, METHODS OF MAKING AND USE THEREOF

#513
20190218228
2019-07-18

Anti-cancer agents and preparation thereof

#514
20190218196
2019-07-18

Furane derivatives as inhibitors of ATAD2

#515
20190216792
2019-07-18

CDK1 inhibitors of acetyl chrysin mannich base derivatives, synthesis and use thereof

#516
20190216774
2019-07-18

TRPV4 antagonists

#517
20190209525
2019-07-11

Dash inhibitors, and uses related thereto

#518
20190203211
2019-07-04

TREATMENT AND PREVENTION OF VIRAL INFECTION

#519
20190201543
2019-07-04

Tissue factor-targeted antibody-drug conjugate

#520
20190192500
2019-06-27

Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation

#521
20190183844
2019-06-20

Methods for treating Gaucher disease

#522
20190177415
2019-06-13

Anti-C10ORF54 antibodies and uses thereof

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20190177272
2019-06-13

2-pyrrolidine phenylhydrazides antibacterial agents

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20190167684
2019-06-06

COMPOSITIONS AND METHODS FOR TREATING HCV

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20190167658
2019-06-06

Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation

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2019-06-06

Synergistic pharmaceutical combination for the treatment of squamous cell carcinoma of head and neck

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2019-05-30

Method of Preparing Solid Dispersions of Active Pharmaceutical Ingredients

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2019-05-16

DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS

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2019-05-09

K-RAS MUTATIONS AND ANTAGONISTS

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2019-05-09

Treatment of addiction and impulse-control disorders using PDE7 inhibitors

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2019-05-09

PHARMACEUTICAL COMBINATIONS

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2019-05-09

FK506 derivative maintaining nerve regeneration activity without immunosuppressive activity, and use thereof

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20190127365
2019-05-02

INHIBITORS OF HEPATITIS C VIRUS REPLICATION

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20190127356
2019-05-02

Substituted Chromanes and Method of Use

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20190119269
2019-04-25

Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof

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20190119243
2019-04-25

Benzothiophene estrogen receptor modulators

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20190119207
2019-04-25

Prodigiosin analogs

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20190117772
2019-04-25

Methods for the treatment of cardiac hypertrophy

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20190117668
2019-04-25

Compositions and methods for treating disorders of circadian and diurnal rhythms using prokineticin 2 agonists and antagonists

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20190111068
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COMBINATION FORMULATION OF TWO ANTIVIRAL COMPOUNDS

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TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY

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LYMPH DIRECTING PRODRUGS

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2019-04-04

INHIBITORS OF BRUTON'S TYROSINE KINASE

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2019-04-04

MYC G-quadruplex stabilizing small molecules and their use

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Difluorolactam compounds as EPreceptor-selective agonists for use in the treatment of EP-mediated diseases and conditions

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FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

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FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

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Voltage-dependent t-type calcium channel blocker

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COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ATRIAL FIBRILLATION

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Salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine

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2019-03-07

NOVEL PHARMACEUTICAL USES

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2,3-epoxy succinyl derivative, preparation method and use thereof

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D-proline derivatives as SAP depleting agent

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2019-02-14

Oligomer-opioid agonist conjugates

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2019-02-07

Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof

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2019-02-07

Medicament used for treating hypertension

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2019-02-07

Medicament for use in treating cardiovascular and cerebrovascular diseases

#558
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2019-02-07

Medicament for use in treating fatty liver, hepatitis and cirrhosis

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2019-02-07

NOVEL CLASS OF COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE

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2019-01-24

Coumarin based HSP90 inhibitors with urea and ether substituents

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2019-01-24

Polymer derivatives having particular atom arrangements

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2019-01-24

METHODS OF USING CASPASE INHIBITORS IN TREATMENT OF LIVER DISEASE

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2019-01-24

Extended, delayed and immediate release formulation method of manufacturing and use thereof

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2019-01-17

CNS-accessible pharmacological chaperones for treatment of acid β-glucosidase-related disease states

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20190010138
2019-01-10

Prodrugs of urolithins and uses thereof

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20190002429
2019-01-03

Derivatives of Xanthone Compounds

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20190002406
2019-01-03

Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B

#568
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2019-01-03

DRUG COMBINATION PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USING THEM

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20190000801
2019-01-03

METHODS OF TREATING AUTOIMMUNE AND/OR GLOMERULONEPHRITIS-ASSOCIATED DISEASES USING SHP2 INHIBITORS

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Purine compounds possessing anticancer activity

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20180369200
2018-12-27

Compounds for the treatment of cancers associated with human papillomavirus

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20180369186
2018-12-27

METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF

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2018-12-13

Multikinase inhibitors for use in the treatment of cancer

#574
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2018-12-06

Small molecule agonists and antagonists of NR2F6 activity

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20180344864
2018-12-06

COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR

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Antibodies, pharmaceutical compositions and methods

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2018-11-22

Citric acid derivative

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2018-11-08

Tricyclic spiro compound

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20180318438
2018-11-08

ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-TWEAKR-ANTIBODIES

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2018-11-08

Antibody drug conjugates of kinesin spindel protein (KSP) inhibitors with anti-CD123-antibodies

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20180318380
2018-11-08

Methods of treating muscular dystrophy

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20180318254
2018-11-08

Substituted pyrrolidines as mGluR5 antagonists

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20180318212
2018-11-08

Composition comprising diacid derivatives and their use in the treatment of collagenic eye disorders

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20180311186
2018-11-01

PHARMACEUTICAL FORMULATION FOR BEDWETTING AND METHOD OF USE THEREOF

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2018-10-11

Treatment of addiction and impulse-control disorders using PDE7 inhibitors

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20180280384
2018-10-04

6-hydroxy-2,5,7,8-tetramethylchroman-compounds for the treatment of chronic obstructive airway diseases

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20180280356
2018-10-04

Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect

#588
20180271859
2018-09-27

TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY

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20180265466
2018-09-20

Pyrrole compound, compositions and process for preparation thereof

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20180264013
2018-09-20

COMPOSITION AND METHODS FOR TREATING SLEEP DISORDERS

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20180263960
2018-09-20

Modulators of CA release-activated CA (CRAC) channels and pharmaceutical uses thereof

#592
20180263959
2018-09-20

Methods of treating muscular dystrophy

#593
20180250294
2018-09-06

6-hydroxy-2,5,7,8-tetramethylchroman-compounds for the treatment of chronic obstructive airway diseases

#594
20180230123
2018-08-16

Benzothiophene estrogen receptor modulators

#595
20180228769
2018-08-16

Synergistic auristatin combinations

#596
20180228765
2018-08-16

IRE-1α inhibitors

#597
20180221341
2018-08-09

3-(1H-pyrrolo[3,2-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof

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20180221334
2018-08-09

Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis

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20180215709
2018-08-02

Type III deiodinase inhibitors and uses thereof

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20180201608
2018-07-19

Compositions and methods for treating neurodegenerative diseases