20314 ⎘
Medicinal preparations containing organic active ingredients; Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
CANCER PROGNOSIS AND THERAPY BASED ON SYNTHEIC LETHALITY
#602Chemical entities that kill senescent cells for use in treating age-related disease
#603Pharmaceutical Combinations
#604N-sulfonyl homoserine lactone derivatives, preparation method and use thereof
#605Efflux-pump inhibitors and therapeutic uses thereof
#606Methods for Treating HCV
#607Anti-dandruff compositions comprising a spirofuranone lactam tetramic acid derivative
#608PPAR agonists
#609Antibody drug conjugates (ADCS) and antibody prodrug conjugates (APDCS) with enzymatically cleavable groups
#610Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
#611Inhibitors of Mc1-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors
#612N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
#613Bicyclic amide compounds and methods of use thereof
#614COMPOUNDS, COMPOSITIONS, AND METHODS FOR INCREASING CFTR ACTIVITY
#615Pharmaceutical compositions and the treatment of overactive bladder
#616COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF ABL1, ABL2 AND BCR-ABL1
#617TREATMENT OF MYCOBACTERIAL INFECTION
#618SUBSTITUTED BENZOFURAN DERIVATIVES AS NOVEL ANTIMYCOBACTERIAL AGENTS
#619COMPOSITIONS AND METHODS FOR DETECTING AND TREATING PERIODONTAL DISEASE
#620Cyclic amine derivative and pharmaceutical use thereof
#621REDUCTION OF TGF BETA SIGNALING IN MYELOID CELLS IN THE TREATMENT OF CANCER
#622Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline
#623Spiro-lactam NMDA receptor modulators and uses thereof
#624Therapeutic treatments using centhaquin
#625NOVEL PHARMACEUTICAL USES
#626GNRH ANALOGUE FORMULATIONS
#627Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
#628Methods of treating autoimmune and/or glomerulonephritis-associated diseases using SHP2 inhibitors
#629Compositions and methods for treating respiratory injury or disease
#630Miliusanes as antiviral agents
#631Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
#632Compounds for use in treatment of mucositis
#633EXTENDED-RELEASE FORMULATION FOR REDUCING THE FREQUENCY OF URINATION AND METHOD OF USE THEREOF
#634Methods of treating an overweight subject
#635Derivatives of 1-[(cyclopentyl or 2-pyrrolidinyl)carbonylaminomethyl]-4-(l,3-thiazol-5-yl) benzene which are useful for the treatment of proliferative, autoimmune or inflammatory diseases
#636Boron-dipyrrin complex and medicament containing the same
#637Benzofurans substituted with bicyclic secondary benzamide as HCV inhibitors
#638INHIBITORS OF BRUTON'S TYROSINE KINASE
#639MYC G-quadruplex stabilizing small molecules and their use
#640Pharmaceutical compositions
#641Anti-wall teichoic antibodies and conjugates
#642Methods of Treating an Overweight or Obese Subject
#643Antibody-drug conjugates (ADCs) of KSP inhibitors with aglycosylated anti-TWEAKR antibodies
#644Pyrrole sulfonyl derivative, preparation method and medical use thereof
#645Tricyclic spiro compound
#646Solid antiviral dosage forms
#647N-methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)-2-aminophenylacetamide derivatives agonists for the kappa opioid receptor
#648Methods for treating or preventing cancer in a KRAS-variant patient and for diagnosing risk of developing multiple primary breast tumors
#649COMPOUNDS, COMPOSITIONS AND METHODS OF USE
#650DOSING REGIMENS FOR BETA-3 ADRENOCEPTOR AGONISTS AND ANTI-MUSCARINIC AGENTS FOR THE TREATMENT AND PREVENTION OF LOWER URINARY TRACT SYMPTOMS AND OVERACTIVE BLADDER
#651Fumagillol heterocyclic compounds and methods of making and using same
#652Antifungal agents
#653Spiro-lactam NMDA receptor modulators and uses thereof
#654SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INHIBITORS
#655COMPOSITIONS AND METHODS FOR AMELIORATING CACHEXIA
#656IRE-1α inhibitors
#657Lymph directing prodrugs
#658EXTENDED, DELAYED AND IMMEDIATE RELEASE FORMULATION METHOD OF MANUFACTURING AND USE THEREOF
#659EXTENDED, DELAYED AND IMMEDIATE RELEASE FORMULATION METHOD OF MANUFACTURING AND USE THEREOF
#660Compounds and Compositions for Cognition-Enhancement, Methods of Making, and Methods of Treating
#661Pyrrolidine amide compounds as histone demethylase inhibitors
#662Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to damage
#663Methods and compositions for the inhibition of Pin1
#664Antiviral agents and uses thereof
#665RAC1 inhibitors for the treatment of Alport glomerular disease
#666Compounds for the treatment of paramyxovirus viral infections
#667Chemical entities that kill senescent cells for use in treating age-related disease
#668Methods of Treating Fatty Liver Disease
#669Prodrug of 1,1′-(1,6-dioxo -1,6-hexanediyl)bis-D-proline
#670DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDTIONS
#671Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine
#672Method of treating polycystic kidney diseases with ceramide derivatives
#673A Method for Topically Treating Actinic Keratosis on the Scalp with Ingenol 3-(3,5-diethylisoxazole-4-carboxylate)
#674COMPOSITIONS FOR TREATMENT OF ACUTE LYMPHOBLASTIC LEUKEMIA AND METHODS OF USE THEREOF
#675CHOLINERGIC ANTAGONISM AS AN ADJUNCT TO CANCER THERAPY
#676Heterocyclic compounds as NaV channel inhibitors and uses thereof
#677Pyrrolidinone derivatives as MetAP-2 inhibitors
#678Use of parthenolide derivatives as antileukemic and cytotoxic agents
#679Compounds for use in treatment of mucositis
#680Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
#681FK506 derivative maintaining nerve regeneration activity without immunosuppressive activity, and use thereof
#682Two part formulation system for ophthalmic delivery
#683Combination formulation of two antiviral compounds
#684Inhibitors of bacterial DNA gyrase with efficacy against gram-negative bacteria
#685Estrogen receptor modulators and uses thereof
#686Oncostatin M (OSM) antagonists for preventing cancer metastasis and IL-6 related disorders
#687Compounds for the treatment of cancers associated with human papillomavirus
#688Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
#689PERSONALIZED TREATMENT OF CANCER USING FGFR INHIBITORS
#690Methods for breast cancer treatment
#691CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
#692Synergistic pharmaceutical combination for the treatment of squamous cell carcinoma of head and neck
#693SKIN WOUND HEALING AND SCAR REDUCTION WITH PROSTAGLANDIN EP4 AGONIST COMBINATIONS
#6946-hydroxy-2,5,7,8-tetramethylchroman-compounds for the treatment of chronic obstructive airway diseases
#695AMORPHOUS FORM OF ELIGLUSTAT HEMITARTARATE
#696Reduction of TGFβ signaling in myeloid cells in the treatment of cancer
#697Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
#698Pharmaceutical combination for the treatment of cancer
#699Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
#700Compounds useful as immunomodulators
#7013,6-disubstituted xanthylium salts
#702Small molecule inhibitor of MYD88 for therapeutic treatment against alphavirus and staphylococcal enterotoxin infections and toxin exposure
#703PYRROLIDINE- SUBSTITUTED FLAVONE DERIVATIVES FOR PREVENTION OR TREATMENT OF ORAL MUCOSITIS
#704Methods for treating occular irritation involving tearing by administering modulators of TRPM8
#705Fumagillol heterocyclic compounds and methods of making and using same
#706Amido compounds as RORγt modulators and uses thereof
#707METHODS OF TREATING OR PREVENTING PRETERM LABOR
#708METHODS OF CANCER THERAPY
#709TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE
#710OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF
#711Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
#712Method for treating vaginal dryness by administering transient receptor potential cation channel subfamily M member 8 (TRPM8) receptor agonists
#713Compositions and methods for treating cancers associated with ETBR activation
#714Antiviral compounds
#715Treatment for diabetes in patients inappropriate for metformin therapy
#716Spliceostatin analogs and methods for their preparation
#717NOVEL HETEROBICYCLIC COMPOUNDS AS KAPPA OPIOID AGONISTS
#718Therapeutics for the treatment of glaucoma
#719Oligomer-opioid agonist conjugates
#720SHP2 inhibitors and methods of treating autoimmune and/or glomerulonephritis-associated diseases using SHP2 inhibitors
#721Uses of sesquiterpene lactone compounds and their derivatives in drugs preparation
#722Cyclic peroxides as prodrugs for selective delivery of agents
#723NOVEL COMPOUNDS HAVING ANTI-ALLODYNIC AND ANTIHYPERALGESIC ACTIVITY
#724Inhibitors of Bruton's tyrosine kinase
#725Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to damage
#726Tricyclic compounds and methods of making and using same
#727Aryl substituted aminomethyl spectinomycin analogs as antibacterial agents
#728Selective Estrogen Receptor Modulators With Short Half-Lives and Uses Thereof
#729Hydroxy formamide derivatives and their use
#730Difluorolactam compositions for EP-mediated osteo related diseases and conditions
#7312-acylaminopropoanol-type glucosylceramide synthase inhibitors
#732TOFA analogs useful in treating dermatological disorders or conditions
#733Antigen binding proteins
#734Prodrugs of urolithins and uses thereof
#735Method for preparing a polymeric reagent
#736Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis
#737Castration-resistant prostate cancer
#738Compositions and methods for treating respiratory injury or disease
#739ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
#740Ex vivo methods for predicting and confirming in vivo metabolism of pharmaceutically active compounds
#741NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES
#742Coumarin based Hsp90 inhibitors with urea and ether substituents
#743Pyrrolidine GPR40 modulators
#744Substituted imidazo[1,2-a]pyridine compounds as tropomyosin receptor kinase a (TrkA) inhibitors
#745Dithiol compounds, derivatives, and uses therefor
#746Compounds for the treatment of diabetes and disease complications arising from same
#747Antibacterial agents: aryl myxopyronin derivatives
#748SUSTAINED-RELEASE RESERVOIR IMPLANTS FOR INTRACAMERAL DRUG DELIVERY
#749Stabilized pharmaceutical dosage forms comprising atrasentan
#750Kappa opioid receptor compounds
#751Indanyloxydihydrobenzofuranylacetic acids
#752Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer
#753Anti-leukemic agent useful for inducing differentiation in myeloid leukemia cells
#754Bisarylsulfonamides useful in the treatment of inflammation and cancer
#755Compositions and methods for treatment of diabetic retinopathy
#756Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids
#757Identification of small molecules that facilitate therapeutic exon skipping
#758Neuroprotective polyphenol analogs
#759Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
#760Solid antiviral dosage forms
#761Method for induction of a heat shock protein, anti-stress or regulation of an autonomic nerve
#762Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
#763Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
#764Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
#765ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
#766Amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
#767METHOD OF SCREENING AN ANTIBODY
#768Compounds for treatment of alzheimer's disease
#769Use for PAI-1 inhibitor
#770METHODS OF USING CLEAVABLE DRUG CONJUGATES AND COMPOSITIONS THEREOF
#7712-methylthiopyrrolidines and their use for modulating bacterial quorum sensing
#772Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
#773Pharmaceutical combination for the treatment of melanoma
#774Oligomer-opioid agonist conjugates
#775Cleavable drug conjugates, compositions thereof and methods of use
#776METHODS OF TREATING CKD USING PREDICTORS OF FLUID RETENTION
#777AMORPHOUS AND A CRYSTALLINE FORM OF GENZ 112638 HEMITARTRATE AS INHIBITOR OF GLUCOSYLCERAMIDE SYNTHASE
#778Substituted chromanes and method of use
#779Secondary structure stabilized NMDA receptor modulators and uses thereof
#780TREATMENT OF OSTEOARTHRITIS PAIN
#7811-aryl-1-hydroxy-2,3-diamino-propyl amines, 1-heteroaryl-1-hydroxy-2,3-diamino-propyl amines and related compounds having analgesic and/or immuno stimulant activity
#782Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline
#783Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline
#784Synthesis of resorcylic acid lactones useful as therapeutic agents
#785Methods for improving lipid profiles using atrasentan
#786Heteroarylcarboxylic acid ester derivative
#787Methods for treating cognitive disorders using 1-benzyl-1-hydroxy-2,3-diamino-propyl amines, 3-benzyl-3-hydroxy-2-amino-propionic acid amides and related compounds
#788SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME
#789N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
#790Anticancer miliusane derivatives
#791NOVEL PYRROLE DERIVATIVES
#792Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
#793Selective Estrogen Receptor Modulators With Short Half-Lives and Uses Thereof
#794PULSATILE GASTRIC RETENTIVE DOSAGE FORMS
#795Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions
#796PPAR agonists
#797Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis
#798USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS
#799Methods of Treating Acute Kidney Injury
#800Lipophilic curcumin analogs and methods of inhibiting HIV-1, treating latent HIV in the brain, and preventing HIV-mediated cognitive decline and HIV dementia
#801Pharmaceutical composition including migratory factor for guiding pluripotent stem cells to injury
#802Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated pathologies
#803Extended, delayed and immediate release formulation method of manufacturing and use thereof
#804Substituted imidazo[1,2-a]pyridine compounds as tropomyosin receptor kinase a (TrkA) inhibitors
#805Substituted chroman compounds as calcium sensing receptor modulators
#806Delayed-release formulations, methods of making and use thereof
#807Symmetrical marinopyrrole derivatives as potential antibiotic agents
#808Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
#809Methods of treating an overweight or obese subject
#810Extended-release formulation for reducing the frequency of urination and method of use thereof
#811Composition and methods used during anti-HIV treatment
#812Pharmaceutical compositions suitable for parenteral administration comprising aqueous suspensions of benzylamine derivatives having low solubilities
#813COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS
#814METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
#815USP14 inhibitors for treating or preventing viral infections
#816Methods of treating an overweight subject
#817CANCER PROGNOSIS AND THERAPY BASED ON SYNTHEIC LETHALITY
#818Compositions comprising a polymeric reagent and a pharmacologically active agent
#819Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
#820Methods of treating hepatic fibrosis and associated diseases by regulating Rev-ERB activity
#821Cycloproplyamine derivatives useful as inhibitors of histone demethylases KDM1A
#822HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
#823Methods of treating portal hypertension
#824Use of TRMP8 for treating opthalmic diseases or conditions involving tearing
#825Fused ring compounds as hepatitis C virus inhibitors, pharmaceutical compositions and uses thereof
#826Pharmaceutical combinations
#827Hexahydropentaleno derivatives, preparation method and use in medicine thereof
#828Methods of treating muscular dystrophy
#829PYRROLIDINES
#830Absorbable crystalline copolyester-based bioactive hydroforming luminal liner compositions
#831Coumarin compounds as receptor modulators with therapeutic utility
#832Methods and compositions for modulating estrogen receptor mutants
#833Solid antiviral dosage forms
#834THERAPEUTIC COMBINATIONS WITH ESTROGEN RECEPTOR MODULATORS
#835Hematopoietic growth factor mimetic small molecule compounds and their uses
#836INHIBITORS OF HEPATITIS C VIRUS REPLICATION
#837Methods of treating ocular diseases using derivatives of lipoic acid
#838Oligomer-opioid agonist conjugates
#839Pyrrole antifungal agents
#840METHODS FOR TREATING COGNITIVE DISORDERS USING 1-BENZYL-1-HYDROXY-2,3-DIAMINO-PROPYL AMINES, 3-BENZYL-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS
#841Preparation of antibody or an antibody fragment targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof
#8422,3,5-trisubstituted thiophene compounds and uses thereof
#843Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists
#844METHOD OF TREATING POLYCYSTIC KIDNEY DISEASES WITH CERAMIDE DERIVATIVES
#845Modulators of hepatic lipoprotein metabolism
#846Alpha adrenergic receptor modulators
#847Antiviral agent
#848Useful thiophene derivatives in the treatment of diabetes
#849NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF
#850TREATING SEIZURES USING ICE INHIBITORS
#851Method of lowering blood glucose
#852Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof
#853MULTIKINASE INHIBITORS FOR USE IN THE TREATMENT OF CANCER
#854RAC1 inhibitors for the treatment of alport glomerular disease
#855Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions
#856Difluorolactam compositions for EP4-mediated osteo related diseases and conditions
#857Benzene or thiophene derivative and use thereof as VAP-1 inhibitor
#858Inhibitors of Bruton's tyrosine kinase
#859Compounds and methods of treating cancer
#860Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases
#861Methods of treating an overweight or obese subject
#862Synthesis of UDP-glucose: -acylsphingosine glucosyl transferase inhibitors
#863CHROMENONE ANALOGS AS SIRTUIN MODULATORS
#864Topical bioadhesive formulations
#865Carbohydrate-selective receptors
#866Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
#867IRE-1α inhibitors
#868Methods for treating HCV
#869Methods and compositions for the inhibition of Pin1
#870Benzothiophene compound
#871Identification of New Therapeutic Uses for Known Therapeutic Agents
#872Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
#873Fused ring compound for use as mineralocorticoid receptor antagonist
#874Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
#875Azetidine derivatives as antiparasitic agents
#876Oligomer-opioid agonist conjugates
#877Small compounds targeting TACC3
#878SUSTAINED-RELEASE RESERVOIR IMPLANTS FOR INTRACAMERAL DRUG DELIVERY
#879Compounds and Compositions for Cognition-Enhancement, Methods of Making, and Methods of Treating
#880Oncostatin M (OSM) antagonists for preventing cancer metastasis and IL-6 related disorders
#881Marinopyrrole derivatives as anticancer agents
#882Amido compounds as RORγt modulators and uses thereof
#883Methods of treating fatty liver disease
#884Therapy for complications of diabetes
#885Compositions and Methods for Diagnosing, Preventing and Treating Intracranial Aneurysms
#886Substituted chroman compounds as calcium sensing receptor modulators
#887Estrogen antagonists as treatments for sclerosing disorders
#888Selective estrogen receptor modulators with short half-lives and uses thereof
#889ADHESIVE SKIN PATCH
#890NOVEL BINDER-DRUG CONJUGATES (ADCS) AND USE THEREOF
#891Methods for treating HCV
#892Stabilized pharmaceutical dosage forms comprising atrasentan
#893TWO PART FORMULATION SYSTEM FOR OPHTHALMIC DELIVERY
#894Methods of treating ocular diseases using derivatives of lipoic acid
#895Anti-wall teichoic antibodies and conjugates
#896DERIVATIVES OF XANTHONE COMPOUNDS
#897PYRROLIDINE- SUBSTITUTED FLAVONE DERIVATIVES FOR PREVENTION OR TREATMENT OF ORAL MUCOSITIS
#898Proton pump inhibitors
#899Modulators of aldehyde dehydrogenase and methods of use thereof
#900Pharmaceutical composition for treating diabetes