20409 ā
Medicinal preparations containing organic active ingredients; Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring heteroatoms, e.g. piperazine Non-condensed pyrazines
MODULATORS OF THE INTEGRATED STRESS PATHWAY
#302USE OF PROSTACYCLIN ANTAGONISTS FOR TREATING OCULAR SURFACE NOCICEPTION
#303Inhibitors of influenza virus replication and uses thereof
#304Methods for treatment using small molecule potassium-sparing diuretics and natriuretics
#305Compositions and methods for preparing and using mitochondrial uncouplers
#306Phenotype-Based Chemical Screens
#307N-formyl vortioxetine and preparation method thereof and solid preparation of vortioxetine
#308Type II raf kinase inhibitors
#309Ophthalmic formulations of cetirizine and methods of use
#310DIMETHYL SULFOXIDE (DMSO) AND METHYLSULFONYLMETHANE (MSM) FORMULATIONS TO TREAT OSTEOARTHRITIS
#311PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY
#312IDENTIFICATION OF INHIBITORS OF TCPC AND TIR NADase ACTIVITY
#313Substituted bicyclic compounds
#314Combinations of MDM2 inhibitors with inhibitors of ERK for treating cancers
#315Hetero-halo inhibitors of histone deacetylase
#316Undecylenic acid-based nanocarriers for targeted drug delivery
#317Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
#318Therapeutic composition including carbonated solution
#319FORMULATIONS AND METHODS FOR TREATMENT OF FIBROMYALGIA AND RELATED MYOFASCIAL PAIN DISORDERS
#320COMBINATION ANTIBACTERIAL COMPOSITION AND SHORT-COURSE ANTIBACTERIAL REGIMEN
#321PKM2 ACTIVATORS IN COMBINATION WITH REACTIVE OXYGEN SPECIES FOR TREATMENT OF CANCER
#322Biaryloxy derivatives as TTX-S blockers
#323Compounds useful as inhibitors of ATR kinase and combination therapies thereof
#324Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
#325Therapeutic composition including carbonated solution
#326Composition and methods for preventing or reducing the incidence of transient ischemic attacks
#327Inhalable antimicrobial particles and methods of making the same
#328PROSTACYCLIN RECEPTOR AGONISTS FOR REDUCTION OF BODY FAT
#329Compositions and methods for inhibition of MICA/B shedding
#330Diketopiperazine salts for drug delivery and related methods
#331KCNQ2-5 CHANNEL ACTIVATOR
#332Use of ligustrazine nitrone derivatives in prevention and treatment of diabetic complication diseases
#333Inhalable dry powder pharmaceutical composition
#334COMBINATION CANCER THERAPY
#335RAR selective agonists in combination with immune modulators for cancer immunotherapy
#336Treatment of aneurysms
#337COMPOSITIONS AND METHODS FOR TREATING CONDITIONS RELATED TO ADRENOCORTICAL ACTIVITY AND/OR EXCESSIVE STEROID PRODUCTION
#338Pharmaceutical composition comprising selexipag
#339METHOD AND COMPOSITION FOR TREATING ALZHEIMER-TYPE DEMENTIA
#340Methods for predicting and determining responsiveness to activators of JNK kinase
#341COMPOSITIONS AND METHODS FOR TREATMENT OF MICROSPORIDIA INFECTION USING PROTEASOME INHIBITORS INCLUDING IXAZOMIB
#342COMBINATION THERAPY FOR TREATING CANCER
#343DISPENSING CAP CONTAINING A SOLUBILISATE OF A PHARMACEUTICALLY ACTIVE AGENT OR DIETARY SUPPLEMENT
#344Calmodulin inhibitors for the treatment of ribosomal disorders and ribosomapathies
#345BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF PEDIATRIC CHOLESTATIC LIVER DISEASES
#346Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
#347Therapeutic Polymeric Nanoparticles Comprising Lipids and Methods of Making and Using Same
#348LSD1 inhibitors as skeletal muscle hypertrophy inducers
#349AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS
#350Compounds, compositions, and methods for inhibiting bacterial growth
#351Aza-pyridone compounds and uses thereof
#352Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same
#353Compounds and compositions for inhibition of FASN
#354PZA and cytochrome bc1 inhibitor combination treatment
#355Non-platinum-based anti-cancer compounds for use in targeted chemotherapy
#356Three-dimensional microfluidics devices for the delivery of actives
#357Three-dimensional microfluidics devices for the delivery of actives
#358Antiviral compounds and methods
#359COMPOSITION FOR AMELIORATING PERIPHERAL SENSORY NEUROPATHY
#360Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
#361Composition for inhibiting cancer metastasis and treating cancer
#362RESIDENT ARTICLES FOR GRAM-LEVEL DOSING
#363Methods of inhibiting serum glucocorticoid induced kinase 1 (SGKI) as a treatment for salt and water balance diseases
#364Composition for reducing nervous system injury and method of making and use thereof
#365Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase
#366DRUG DELIVERY ARTICLES FOR GRAM-LEVEL DOSING
#367Retrieval systems and related methods
#368Therapeutic uses of a C-RAF inhibitor
#369RAR selective agonists in combination with immune modulators for cancer immunotherapy
#370DIABETES POLYGENIC RISK SCORE
#371Chemical compounds
#372Modulators of MS4A activity
#373RAR selective agonists in combination with immune modulators for cancer immunotherapy
#374AZA-pyridone compounds and uses thereof
#3753,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS
#376Composition for inhibiting survival or growth of tubercle bacillus by adjusting polarization of macrophage, and method using same
#377Heteroaryltrifluoroborate compounds for the treatment of mycobacterial infections
#378Treatment of ischemia
#379Use of ATR and Chk1 inhibitor compounds
#380Pyridine and Pyrazine Derivative for the Treatment of CF
#381Non-selective kinase inhibitors
#382Aminoheteroaryl benzamides as kinase inhibitors
#383Compounds and compositions for inhibition of FASN
#384Compounds and compositions for inhibition of FASN
#385SODIUM CHANNEL BLOCKERS
#386Preventive and therapeutic approach for aberrant cell differentiation and ISR-associated diseases
#387REDUCING CUTANEOUS SCAR FORMATION AND TREATING SKIN CONDITIONS
#388Trifluoroacetyl hydrazide compounds and medical uses thereof
#389Pharmaceutical Compositions Comprising Sorbitan Esters
#390INHIBITOR OF HEME DEGRADATION FOR USE TO IMPROVE ANTIBIOTIC TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTION
#391Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity
#392Modulators of the integrated stress pathway
#393Methods for treatment using small molecule potassium-sparing diuretics and natriuretics
#394Thioacetate compounds, compositions and methods of use
#395Entacapone-related compounds to treat macular degeneration
#396DRY PLATELET COMPOSITION
#397Heterocyclic compound
#398METHODS AND COMPOSITIONS FOR APPETITE CONTROL AND WEIGHT MANAGEMENT
#399A NOVEL TREATMENT REGIMEN INVOLVING SAPROPTERIN DIHYDROCHLORIDE
#400Nitrogen-containing heteroaryl compound and pharmaceutical use thereof
#401Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
#402KCNQ2-5 channel activator
#403Process for the preparation of diphenylpyrazine derivatives
#404Transdermal Delivery of Selexipag Metabolite
#405PKC-delta-I inhibitor formulations and uses thereof
#406CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY
#407Substituted bicyclic compounds
#408TB BIOMARKERS
#409RAR selective agonists in combination with immune modulators for cancer immunotherapy
#410PHASE 2 INDUCERS AND RELATED SIGNALING PATHWAYS PROTECT CARTILAGE AGAINST INFLAMMATION, APOPTOSIS AND STRESS
#411ROR GAMMA (RORY) MODULATORS
#412Diketopiperazine salts for drug delivery and related methods
#413Composition and combined medication method for treating enterovirus infection
#414Multi-drug therapies for tuberculosis treatment
#415Optical method for the detection of Alzheimer's disease using curcumin
#416Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
#417Inhibitors of Ataxia-Telangiectasia Mutated and Rad3-related protein kinase (ATR) for use in methods of treating cancer
#418Compounds and compositions for inhibition of FASN
#419Compositions and methods for treating conditions related to adrenocortical activity and/or excessive steroid production
#420Phenylethynyl-substituted benzenes and heterocycles for the treatment of cancer
#421Composition and methods for preventing or reducing the incidence of transient ischemic attacks
#422SHIP1 MODULATORS AND METHODS RELATED THERETO
#423Trifluoroacetyl hydrazide compounds and methods of preparation and uses thereof
#424KCNQ2-5 channel activator
#425Pyruvate kinase activators for use in therapy
#426Cancer diagnostics, therapeutics, and drug discovery associated with macropinocytosis
#427Pharmaceutical composition containing 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide
#428Pharmaceutical composition containing 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy]-N-(methylsulfonyl)acetamide
#429Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases
#430Methylated cyclodextrins and methods for the production thereof
#431FORMULATIONS OF AZAINDOLE COMPOUNDS
#432Pharmaceutical composition, use of mefloquine in fixed dose, and method for treating tuberculosis
#433Method for treating cancer using a combination of DNA damaging agents and ATR inhibitors
#434AMINOQUINOLINE COMPOUNDS HAVING ANTICANCER ACTIVITY
#435METHOD AND COMPOSITION FOR TREATING ALZHEIMER-TYPE DEMENTIA
#436BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS
#4371,2-substituted cyclopentanes as orexin receptor antagonists
#438Farnesoid X receptor agonists and uses thereof
#439Combination therapy for treating cancer
#440COMBINATION ANTIBACTERIAL COMPOSITION AND SHORT-COURSE ANTIBACTERIAL REGIMEN
#441Ophthalmic formulations of cetirizine and methods of use
#442Treatment of ischemia
#443Methods, compositions, and uses of novel Fyn kinase inhibitors
#444Farnesoid X receptor agonists and uses thereof
#445Anti-cancer agent comprising aminoacetonitrile compound as active ingredient
#446Solid state forms of selexipag
#447Dimethyl sulfoxide (DMSO) or DMSO and methylsulfonylmethane (MSM) formulations to treat infectious diseases
#448Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
#449ANTICOAGULANT REVERSAL AGENTS
#450Anticancer agent comprising aminoacetonitrile compound as active ingredient
#451Anti-malarial agents
#452SPRAY DRY FORMULATIONS
#453Chemical compounds
#454Non-selective kinase inhibitors
#455SHIP1 modulators and methods related thereto
#456Inhibitors of Mc1-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors
#457USE OF TRIMETHAZINE IN PREPARATION OF DRUGS FOR PREVENTING AND TREATING LIVER DISEASES
#458ROR gamma (RORĪ³) modulators
#459COMPOUNDS
#460Piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction
#461Calmodulin inhibitors for the treatment of ribosomal disorders and ribosomapathies
#462Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
#463Cyclic vinylogous amides as bromodomain inhibitors
#464Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity
#465Inhibitors of histone deacetylase
#466SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS
#467Treating or preventing nephrogenic diabetes insipidus
#468DIMETHYL SULFOXIDE (DMSO) AND METHYLSULFONYLMETHANE (MSM) FORMULATIONS TO TREAT OSTEOARTHRITIS
#469Monocyclic compound
#470Inhibitors of influenza viruses replication
#471Glutaminase inhibitors
#472Use of aliginate oligomers and CFTR modulators in treatment of conditions associated with CFTR dysfunction
#473Compounds and compositions for inhibition of FASN
#474Compositions for use in treating glioblastoma
#475Methods for treating malaria using potassium channel inhibitors
#476Aminoheteroaryl benzamides as kinase inhibitors
#477METHODS OF REGULATING UPTAKE AND TRANSCELLULAR TRANSPORT OF LEUKOCYTES AND THERAPEUTICS
#478GLP-1 receptor modulators
#479Methods and pharmaceutical compositions for the treatment of ebola virus disease
#480INHIBITORS OF HISTONE DEACETYLASE
#481BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF PEDIATRIC CHOLESTATIC LIVER DISEASES
#482COMBINATION THERAPY FOR TUBERCULOSIS
#4833,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds
#484FAS inhibitors and methods associated therewith
#485Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
#486Trifluoromethylpropanamide derivatives
#487Treatment of ischemia
#4883,5-diamino-6-chloro-Nā(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide
#489KCNQ2-5 channel activator
#490Multi-drug therapies for tuberculosis treatment
#491Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity
#492Mitochondrial uncouplers for treatment of metabolic diseases and cancer
#493Method and composition for treating Alzheimer-type dementia
#494Arylalkyl-and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
#495METHOD FOR TREATING HYPERGLYCEMIA WITH GLP-1
#496Substituted bicyclic compounds
#497HIF-2Ī± inhibitors for treating iron overload disorders
#498FLUORESCENT PYRAZINE DERIVATIVES AND METHODS OF USING THE SAME IN ASSESSING RENAL FUNCTION
#499CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY
#500INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL
#501INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL
#502Diketopiperazine salts for drug delivery and related methods
#503Sodium channel blockers
#504Stable sodium channel blockers
#505PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
#506USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK)
#507Antiviral compounds and methods
#508N-substituted-5-substituted phthalamic acids as sortilin inhibitors
#509Methods and compositions for treating alcohol use disorders
#510Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, AIDs, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
#511TREATMENT OF MELANOMA BY BLOCKING BENZAMIL SENSITIVE ION CHANNELS/EXCHANGERS
#512SHIP1 modulators and methods related thereto
#513Drug combinations to treat multiple myeloma
#514COMPOUNDS AND USES
#515Composition for reducing nervous system injury and method of making and use thereof
#516Pharmaceutical compositions comprising sorbitan esters
#517Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
#518Composition for reducing nervous system injury and method of making and use thereof
#519EPITHELIAL ION CHANNEL (ENAC) BLOCKERS TO TREAT PSORIASIS
#520Ophthalmic formulations of cetirizine and methods of use
#521METHOD FOR DETECTING OR TREATING TRIPLE NEGATIVE BREAST CANCER
#522Dry platelet composition
#523Combination therapy to treat mycobacterium diseases
#524Compounds and methods for inducing chondrogenesis
#525Chemical compounds
#526DGAT1 inhibition for treatment of demyelinating inflammatory disease
#527Methods of diagnosing and treating tuberculosis
#528Pyridine and pyrazine derivative for the treatment of CF
#5291,2-substituted cyclopentanes as orexin receptor antagonists
#530Anticoagulant reversal agents
#531BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS
#532Substituted bicyclic compounds
#533Methods and compositions for treating nephrogenic diabetes insipidus
#534PARASITE CONTROL AGENT FOR PARASITICIDE
#535Sodium channel blockers for skin disorders
#536TREATMENT FOR RESPIRATORY DISEASE
#537Medicament for suppressing malignant tumor metastasis
#538Nanoparticle drug delivery
#539PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUG AND NEUTRAL POLYMERS
#540Minimizing intestinal dysfunction
#541Treating or preventing nephrogenic diabetes insipidus
#542Use of trimetazidine as a hepatoprotective medicine in prevention and treatment of liver diseases and conditions
#543Inhibitors of histone deacetylase
#544fermentation product and method of producing the same
#545Therapeutic methods
#546Glutaminase inhibitors
#547Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
#548Inhibitors of the renal outer medullary potassim channel
#549METHOD OF TREATING TUBERCULOSIS
#550NOVEL INHIBITORS OF GLUTAMINASE
#551Formulation Solution Adapted to Prolong Plasma Times of Drugs in Mammals Including Humans
#552Fluorescent pyrazine derivatives and methods of using the same in assessing renal function
#553Inhibitors of histone deacetylase
#554COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
#555COMPOSITION FOR REDUCING NERVOUS SYSTEM INJURY AND METHOD OF MAKING AND USE THEREOF
#556Treatment of ischemia
#557Compounds
#558NRF2 INHIBITORS AND COMPOSITIONS FOR TREATING MYCOBACTERIAL INFECTIONS
#559Inhibitors of influenza viruses replication
#560Inhibitors of histone deacetylase
#561Diketopiperazine salts for drug delivery and related methods
#562FORMULATIONS OF AZAINDOLE COMPOUNDS
#563Non-platinum-based anti-cancer compounds for use in targeted chemotherapy
#564Spray-dry formulations
#565GLP-1 receptor modulators
#566Aza-pyridone compounds and uses thereof
#567Pharmaceutical combinations for the treatment of cancer
#568Combination Therapy for Tuberculosis
#569Anticancer agent comprising aminoacetonitrile compound as active ingredient
#570Cyclic vinylogous amides as bromodomain inhibitors
#571Dithiol mucolytic agents
#572METHOD OF REGULATING NEURONAL AXON ELONGATION
#573Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
#574Composition for reducing nervous system injury and method of making and use thereof
#575Antitubercular composition comprising rifampicin, isoniazid, ethambutol and pyrazinamide and its process of preparation
#576Compounds for treatment of alzheimer's disease
#577Composition for reducing nervous system injury and method of making and use thereof
#578Method and composition for treating alzheimer-type dementia
#579Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
#580Phenol derivatives and pharmaceutical or cosmetic use thereof
#581Pyruvate kinase activators for use in therapy
#582Ophthalmic formulations of cetirizine and methods of use
#583Composition comprising at least two influenza A virus-neutralizing-binding molecules
#584Treatment of protein degradation disorders
#585TYPE II RAF KINASE INHIBITORS
#586Pesticidal compositions and processes related thereto
#587Bioavailable Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes via an Ecdysone Receptor Complex
#588Pesticidal compositions and processes related thereto
#589Enhanced treatment regimens using mTOR inhibitors
#590Pesticidal compositions and processes related thereto
#591Pesticidal compositions and processes related thereto
#592Compounds useful as inhibitors of ATR kinase and combination therapies thereof
#593Inhibitors of the renal outer medullary potassium channel
#594Therapeutic compositions containing macitentan
#595STABLE SODIUM CHANNEL BLOCKERS
#596Substituted carboxylic acid derivatives as aggrecanase inhibitors for the treatment of osteoarthritis
#597Amine compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity
#598Method for treating cancer using a combination of Chk1 and ATR inhibitors
#599Composition for treatment of pathogens that are resistant to tetracyclines
#600Non-selective kinase inhibitors