ClassID:

20412

A61K31/4985 - page 7 - CPC Classification

Classification description:

Medicinal preparations containing organic active ingredients; Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring heteroatoms, e.g. piperazine Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems

Recent Application in this class:
#1801
20180140653
2018-05-24

Compositions, kits and methods for treating type II diabetes mellitus

#1802
20180140601
2018-05-24

Bicyclic compounds and methods for their use in treating autism spectrum disorders and neurodevelopmental disorders

#1803
20180140595
2018-05-24

APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

#1804
20180133213
2018-05-17

Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors

#1805
20180133200
2018-05-17

Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors

#1806
20180127425
2018-05-10

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

#1807
20180127388
2018-05-10

THERAPEUTIC COMPOUNDS

#1808
20180127386
2018-05-10

METHODS USING HDAC11 INHIBITORS

#1809
20180127359
2018-05-10

Nitrite salts of 1,1-dimethylbiguanide, pharmaceutical compositions, and methods of use

#1810
20180125867
2018-05-10

COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS

#1811
20180125852
2018-05-10

Compositions and methods for treatment of glioma

#1812
20180125843
2018-05-10

Method of treating metabolic disorders and depression with dopamine receptor agonists

#1813
20180125842
2018-05-10

Ergoloid for Cancer

#1814
20180118766
2018-05-03

Btk inhibitors

#1815
20180118734
2018-05-03

Therapeutic compounds

#1816
20180117065
2018-05-03

FXR agonist compositions for combination therapy

#1817
20180117041
2018-05-03

LIVER X RECEPTOR MODULATORS

#1818
20180117040
2018-05-03

Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation

#1819
20180117039
2018-05-03

Combination therapy for treating pulmonary hypertension

#1820
20180117032
2018-05-03

Pharmacologically active compounds

#1821
20180112273
2018-04-26

TUMOR BIOMARKERS AND USE THEREOF

#1822
20180111944
2018-04-26

(R)-pirlindole and its pharmaceutically acceptable salts for use in medicine

#1823
20180110776
2018-04-26

Polycyclic-carbamoylpyridone compounds and their pharmaceutical use

#1824
20180110775
2018-04-26

Compositions and methods for treating mitochondrial diseases

#1825
20180110724
2018-04-26

FILM DOSAGE FORM WITH MULTIMODAL AND PARTICLE SIZE DISTRIBUTIONS

#1826
20180105523
2018-04-19

Anxiolytic compounds

#1827
20180099973
2018-04-12

PDE1 inhibitor

#1828
20180099967
2018-04-12

FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INTEGRASE INHIBITORS

#1829
20180098992
2018-04-12

ANTIVIRAL THERAPY

#1830
20180092916
2018-04-05

METHODS OF TREATING DISEASE-INDUCED ATAXIA AND NON-ATAXIC IMBALANCE

#1831
20180087086
2018-03-29

CELL EGRESS AND INVASION INHIBITORS AND THEIR USE AS ANTIPARASITICAL AGENTS

#1832
20180079752
2018-03-22

BTK INHIBITORS

#1833
20180078559
2018-03-22

Targeting cGMP-related phosphodiesterases to reduce cyst formation in cystic kidney disease, and related materials and methods

#1834
20180078549
2018-03-22

SOLID ORAL FILM DOSAGE FORMS AND METHODS FOR MAKING SAME

#1835
20180072759
2018-03-15

Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors

#1836
20180072673
2018-03-15

N-(pyridin-2-yl)pyridine-sulfonamide derivatives and their use in the treatment of disease

#1837
20180072671
2018-03-15

Inhibitors of histone deacetylase

#1838
20180071320
2018-03-15

Methods and materials for treating calcific aortic valve stenosis

#1839
20180071302
2018-03-15

SYK inhibitors

#1840
20180071287
2018-03-15

Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3- ]pyrazin-2(1)-one, a solid form there of and methods of their use

#1841
20180071286
2018-03-15

Heteroaryl pyridone and aza-pyrodine compounds

#1842
20180071285
2018-03-15

Systems pharmacology for treating ocular disorders

#1843
20180065971
2018-03-08

SGC stimulators

#1844
20180064785
2018-03-08

Method of ameliorating or preventing the worsening or the progression of symptoms of BPH

#1845
20180064718
2018-03-08

Compounds, compositions and methods useful for cholesterol mobilization

#1846
20180057507
2018-03-01

INHIBITORS OF DUAL LEUCINE ZIPPER (DLK) KINASE FOR THE TREATMENT OF DISEASE

#1847
20180057502
2018-03-01

Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-alpha]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof

#1848
20180057500
2018-03-01

PYRAZOLE CARBOXAMIDE COMPOUNDS AND METHODS OF USE

#1849
20180055890
2018-03-01

Pancreatic endocrine progenitor cell therapies for the treatment of obesity and type 2 diabetes (T2D)

#1850
20180055772
2018-03-01

Method of making particles for use in a pharmaceutical composition

#1851
20180051035
2018-02-22

Thienopyrazine inhibitors of IRAK4 activity

#1852
20180051027
2018-02-22

Carboxamide inhibitors of IRAK4 activity

#1853
20180051019
2018-02-22

Composition and method for treating metabolic disorders

#1854
20180050997
2018-02-22

Compounds and compositions for inhibition of FASN

#1855
20180050051
2018-02-22

Fumagillol derivatives

#1856
20180050027
2018-02-22

Treatment of pemphigus

#1857
20180042924
2018-02-15

Pharmaceutical formulations, processes, solid forms and methods of use relating to 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one

#1858
20180037895
2018-02-08

COMPOSITIONS AND METHODS FOR EFFICACIOUS AND SAFE DELIVERY OF SIRNA USING SPECIFIC CHITOSAN-BASED NANOCOMPLEXES

#1859
20180037590
2018-02-08

Substituted quinoxalines as PDE-10 inhibitors

#1860
20180037577
2018-02-08

INHIBITORS OF JUN N-TERMINAL KINASE

#1861
20180036312
2018-02-08

Novel Scaffolds for Intracellular Compound Delivery for the Detection of Cancer Cells

#1862
20180036247
2018-02-08

Pharmaceutical compositions

#1863
20180030049
2018-02-01

Preparation method for praziquantel and intermediate compounds thereof

#1864
20180030003
2018-02-01

Tricyclic compounds and uses thereof in medicine

#1865
20180028533
2018-02-01

Medicinal solution to be continuously or pulse-delivered to the eye for treating ophthalmological conditions/maladies

#1866
20180022751
2018-01-25

N-substituted 8-[(2,6-difluorobenzyl)oxy]-2,6- dimethylimidazo[1,2-a]pyrazin-3-carboxamide derivatives as stimulators of soluble guanylate cyclase (SGC) for the treatment of cardiovascular diseases

#1867
20180022746
2018-01-25

Indazole and azaindazole substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

#1868
20180022745
2018-01-25

Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

#1869
20180022744
2018-01-25

Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

#1870
20180021334
2018-01-25

Use of ergot alkaloids as an anthelmintic agent

#1871
20180021312
2018-01-25

Benzoisoxazole-substituted compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

#1872
20180016259
2018-01-18

QUINAZOLINE INHIBITORS OF ACTIVATING MUTANT FORMS OF EPIDERMAL GROWTH FACTOR RECEPTOR

#1873
20180009828
2018-01-11

Substituted imidazo[1,5-a]pyrazines as Btk inhibitors

#1874
20180008608
2018-01-11

Combination methods for treating cancers

#1875
20180008605
2018-01-11

Pteridine dione monocarboxylate transporter inhibitors

#1876
20180002344
2018-01-04

HETEROARYL ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

#1877
20170369509
2017-12-28

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

#1878
20170369493
2017-12-28

6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of MGLUR2 receptors

#1879
20170369492
2017-12-28

1,3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES AND ANALOGUES USEFUL IN THE TREATMENT OR PREVENTION OF DIABETES MELLITUS, OBESITY, AND INFLAMMATORY BOWEL DISEASE

#1880
20170368085
2017-12-28

BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF PEDIATRIC CHOLESTATIC LIVER DISEASES

#1881
20170368040
2017-12-28

Processes for preparing dolutegravir and cabotegravir and analogues thereof

#1882
20170362252
2017-12-21

Spirocyclic heterocycle compounds useful as HIV integrase inhibitors

#1883
20170362247
2017-12-21

Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-α]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl and solid state forms thereof

#1884
20170362246
2017-12-21

INHIBITORS OF BRUTON'S TYROSINE KINASE

#1885
20170362243
2017-12-21

BIARYLETHER IMIDAZOPYRAZINE BTK INHIBITORS

#1886
20170362242
2017-12-21

Benzamide imidazopyrazine Btk inhibitors

#1887
20170362240
2017-12-21

4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors

#1888
20170360874
2017-12-21

Combination formulation of three antiviral compounds

#1889
20170360783
2017-12-21

Methods for Treating HCV

#1890
20170360756
2017-12-21

Substituted heterocycles as bromodomain inhibitors

#1891
20170355689
2017-12-14

HEPATITIS C VIRUS INHIBITOR

#1892
20170349593
2017-12-07

BTK INHIBITORS

#1893
20170348324
2017-12-07

DERIVATIVES OF BETULIN

#1894
20170348309
2017-12-07

BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

#1895
20170342083
2017-11-30

Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-α]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof

#1896
20170342078
2017-11-30

Heterocyclic inhibitors of PTPN11

#1897
20170342076
2017-11-30

Tertiary alcohol imidazopyrazine BTK inhibitors

#1898
20170342067
2017-11-30

Therapeutic compounds and uses thereof

#1899
20170340632
2017-11-30

Bromocriptine formulations

#1900
20170340631
2017-11-30

BTK inhibitors

#1901
20170340271
2017-11-30

METHODS FOR IDENTIFYING RESPONDERS TO DOPAMINERGIC NEURONAL ENHANCING THERAPIES FOR THE TREATMENT OF ELEVATED HEART RATE AND METABOLIC OR CARDIOVASCULAR CONDITIONS

#1902
20170333428
2017-11-23

Methods for Treating HCV

#1903
20170327514
2017-11-16

Flap modulators

#1904
20170327501
2017-11-16

Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-α]pyrazine-2-carboxamides as RSK inhibitors

#1905
20170327497
2017-11-16

SUBSTITUTED 6-AZA-ISOINDOLIN-1-ONE DERIVATIVES

#1906
20170326145
2017-11-16

Composition comprising phosphodiesterase type 5 inhibitor for inhibiting apoptosis of nerve cells

#1907
20170326141
2017-11-16

Method of treatment of chronic cough administering orvepitant in combination with other therapeutic agents

#1908
20170326140
2017-11-16

NOVEL USES

#1909
20170326139
2017-11-16

COMBINATION THERAPY FOR MALE SEXUAL DYSFUNCTION

#1910
20170320823
2017-11-09

Synergistic compositions

#1911
20170319580
2017-11-09

Organic compounds

#1912
20170319579
2017-11-09

PHARMACEUTICAL FORMULATION FOR REDUCING FREQUENCY OF URINATION AND METHOD OF USE THEREOF

#1913
20170319474
2017-11-09

Ophthalmic device having therapeutic agent delivery capability and method of forming same

#1914
20170313717
2017-11-02

GLP-1 receptor modulators

#1915
20170313712
2017-11-02

Diheteroaryl histone deacetylase inhibitors and their use in therapy

#1916
20170312288
2017-11-02

Treatment of erectile dysfunction and other indications

#1917
20170312286
2017-11-02

COMPOSITIONS AND METHODS FOR LIPID METABOLISM DISORDER

#1918
20170312278
2017-11-02

Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines

#1919
20170312277
2017-11-02

Compounds for treatment of fibrosis diseases

#1920
20170305923
2017-10-26

Fused tricyclic heterocyclic compounds as HIV integrase inhibitors

#1921
20170304302
2017-10-26

Compounds for treatment of cancer

#1922
20170304301
2017-10-26

Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones

#1923
20170304262
2017-10-26

SGLT-2 inhibitors for treating metabolic disorders in patients with renal impairment or chronic kidney disease

#1924
20170296543
2017-10-19

Solid pharmaceutical compositions comprising biopterin derivatives and uses of suchcompositions

#1925
20170296537
2017-10-19

Azabicyclo derivatives, process for preparation thereof and medical use thereof

#1926
20170296534
2017-10-19

Use of levocetirizine and montelukast in the treatment of autoimmune disorders

#1927
20170296531
2017-10-19

Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases

#1928
20170291911
2017-10-12

Ataxia telengiectasia and rad3-related (ATR) inhibitors and methods of their use

#1929
20170283417
2017-10-05

Substituted pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines for inhibiting serotonin reuptake transporter activity

#1930
20170281758
2017-10-05

CALICHEAMICIN ANTIBODY DRUG CONJUGATES LINKING AN AMIDOACETYL GROUP TO A SUGAR MOIETY ON CALICHEAMICIN

#1931
20170281636
2017-10-05

ANTIVIRAL THERAPY

#1932
20170275302
2017-09-28

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

#1933
20170275271
2017-09-28

6-(5-hydroxy-1H-pyrazol-1-YL)nicotinamide inhibitors of PHD

#1934
20170273989
2017-09-28

Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction

#1935
20170273976
2017-09-28

6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors

#1936
20170273920
2017-09-28

Particulate materials

#1937
20170273919
2017-09-28

Therapeutic approaches for treating Parkinson's disease

#1938
20170267694
2017-09-21

Crystalline forms of an antiviral compound

#1939
20170267693
2017-09-21

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

#1940
20170267682
2017-09-21

6,7-dihydropyrazolo[1,5-α]pyrazin-4(5)-one compounds and their use as negative allosteric modulators of mGluR2 receptors

#1941
20170267677
2017-09-21

Substituted pyrazolo[1,5-A] pyridine as tropomyosin receptor kinase (TrK) inhibitors

#1942
20170267660
2017-09-21

Compounds and methods for kinase modulation, and indications therefor

#1943
20170266192
2017-09-21

METHODS FOR IMPROVING DIAPHRAGM FUNCTION

#1944
20170266191
2017-09-21

Therapeutic combination of PI3K inhibitor and a BTK inhibitor

#1945
20170260203
2017-09-14

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

#1946
20170253616
2017-09-07

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

#1947
20170253590
2017-09-07

Small molecule IRE1-α inhibitors

#1948
20170252356
2017-09-07

Compounds and compositions for treating HIV with derivatives of Betulin

#1949
20170252350
2017-09-07

SMALL MOLECULE IRE1-ALPHA INHIBITORS

#1950
20170247381
2017-08-31

Dosage form compositions comprising an inhibitor of bruton's tyrosine kinase

#1951
20170246118
2017-08-31

Long acting pharmaceutical compositions

#1952
20170240563
2017-08-24

Compositions and methods for regulating glucose homeostasis and insulin action

#1953
20170240549
2017-08-24

Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors

#1954
20170240532
2017-08-24

Azetidinyloxyphenylpyrrolidine compounds

#1955
20170239351
2017-08-24

Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, a PD-1 Inhibitor, and/or a PD-L1 Inhibitor

#1956
20170239281
2017-08-24

Combination treatment of SGLT2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals

#1957
20170239276
2017-08-24

PHARMACEUTICAL COMBINATIONS OF SITAGLIPTIN

#1958
20170239257
2017-08-24

Methods of Use of Inhibitors of Phosphodiesterases and Modulators of Nitric Oxide, Reactive Oxygen Species, and Metalloproteinases in the Treatment of Peyronie's Disease, Arteriosclerosis and Other Fibrotic Diseases

#1959
20170239244
2017-08-24

Dry eye treatments

#1960
20170239175
2017-08-24

TOPICAL ANORGASMIA THERAPY

#1961
20170233373
2017-08-17

Crystalline (2S)-3-[(3S,4S)-3-[(1R)-1-hydroxyethyl]-4-(4-methoxy-3-{[1-(5-methylpyridin-2-yl)azetidin-3-yl]oxy}phenyl)-3-methylpyrrolidin-1-yl]-3-oxopropane-1,2-diol

#1962
20170231995
2017-08-17

BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment

#1963
20170231986
2017-08-17

Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor

#1964
20170231931
2017-08-17

PRODUCTS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS COURSING WITH A COGNITION DEFICIT OR IMPAIRMENT, AND OF NEURODEGENERATIVE DISEASES

#1965
20170226113
2017-08-10

Pyridines, pyrimidines, and pyrazines, as BTK inhibitors and uses thereof

#1966
20170224911
2017-08-10

Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, AIDs, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like

#1967
20170224837
2017-08-10

COMBINATION OF ABCG2 INHIBITORS WITH SACITUZUMAB GOVITECAN (IMMU-132) OVERCOMES RESISTANCE TO SN-38 IN TROP-2 EXPRESSING CANCERS

#1968
20170224819
2017-08-10

Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK 4/6 Inhibitor

#1969
20170224705
2017-08-10

Bicyclic heterocycle compounds and their uses in therapy

#1970
20170224695
2017-08-10

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

#1971
20170224694
2017-08-10

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

#1972
20170224691
2017-08-10

PDE INHIBITORS IN IMMUNOTHERAPY

#1973
20170224688
2017-08-10

Methods of Using BTK Inhibitors to Treat Dermatoses

#1974
20170217972
2017-08-03

Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of MGLUR2 receptors

#1975
20170217971
2017-08-03

Substituted 6,7-dihydropyrazolo[1,5-a] pyrazines as negative allosteric modulators of mGlUR2 receptors

#1976
20170217940
2017-08-03

Fused tetracyclic heterocyclic compounds and methods of use thereof for the treatment of viral diseases

#1977
20170217918
2017-08-03

Antidiabetic bicyclic compounds

#1978
20170216301
2017-08-03

Bicyclic bromodomain inhibitors

#1979
20170216285
2017-08-03

Substituted pyrrolo[2,3-b]quinoxalines for cancer therapy

#1980
20170216284
2017-08-03

ANTIVIRAL THERAPY

#1981
20170209539
2017-07-27

Therapeutic Treatment For Metabolic Syndrome, Type 2 Diabetes, Obesity, Or Prediabetes

#1982
20170209439
2017-07-27

Compositions and methods for treating rebound erythema associated with topical alpha-adrenergic agonists

#1983
20170202865
2017-07-20

Combination formulation of two antiviral compounds

#1984
20170196861
2017-07-13

Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile

#1985
20170196860
2017-07-13

Orvepitant for chronic cough therapy

#1986
20170190701
2017-07-06

FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INTEGRASE INHIBITORS

#1987
20170189398
2017-07-06

Methods and compositions for sleep disorders and other disorders

#1988
20170189397
2017-07-06

HEADACHE PRE-EMPTION BY DIHYDROERGOTAMINE TREATMENT DURING HEADACHE PRECURSOR EVENTS

#1989
20170183350
2017-06-29

Organic compounds

#1990
20170182056
2017-06-29

Quinolinyl modulators of RORγt

#1991
20170182044
2017-06-29

Treatment of cancer with dihydropyrazino-pyrazines

#1992
20170182043
2017-06-29

Anti-neoplastic combinations and dosing regimens using CDK4/6 inhibitor compounds to treat RB-positive tumors

#1993
20170182042
2017-06-29

Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino [2,3-B]pyrazin-2(1H)-one, a solid form thereof and methods of their use

#1994
20170182029
2017-06-29

Substituted bicyclic compounds as bromodomain inhibitors

#1995
20170182014
2017-06-29

Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use

#1996
20170174704
2017-06-22

Quinoxaline compounds and uses thereof

#1997
20170174689
2017-06-22

Substituted indole Mcl-1 inhibitors

#1998
20170173034
2017-06-22

COMBINATION OF A JAK INHIBITOR AND A SYK INHIBITOR FOR TREATING CANCERS AND INFLAMMATORY DISORDERS

#1999
20170173006
2017-06-22

Particulate materials

#2000
20170172963
2017-06-22

COMPOSITIONS AND METHODS FOR THE PREVENTION AND OR TREATMENT OF SCHISTOSOMIASIS

#2001
20170166572
2017-06-15

Imidazotriazinone or imidazopyrazinone derivatives, and use thereof

#2002
20170165271
2017-06-15

Compositions and Methods for the Delivery of Therapeutics

#2003
20170165270
2017-06-15

Heteroaromatic Compounds and their Use as Dopamine D1 Ligands

#2004
20170165259
2017-06-15

COMBINED MODULATION OF IRE1

#2005
20170157119
2017-06-08

Solid oral film dosage forms and methods for making same

#2006
20170157102
2017-06-08

USE OF PERHEXILINE

#2007
20170145015
2017-05-25

(R)-PIRLINDOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS FOR USE IN MEDICINE

#2008
20170143712
2017-05-25

Methods of Treating Cancers, Immune and Autoimmune Diseases, and Inflammatory Diseases Based on BTK Occupancy and BTK Resynthesis Rate

#2009
20170143711
2017-05-25

NOVEL USES

#2010
20170143710
2017-05-25

Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine

#2011
20170143709
2017-05-25

(S)-pirlindole and its pharmaceutically acceptable salts for use in medicine

#2012
20170143708
2017-05-25

Compounds, compositions and methods of agelastatin alkaloids

#2013
20170143701
2017-05-25

CARBOHYDRATE METABOLISM-AMELIORATING AGENT

#2014
20170143623
2017-05-25

ORODISPERSIBLE FILMS HAVING QUICK DISSOLUTION TIMES FOR THERAPEUTIC AND FOOD USE

#2015
20170137405
2017-05-18

Compounds for the treatment of HIV

#2016
20170136017
2017-05-18

Liver X receptor modulators

#2017
20170136016
2017-05-18

Method for treating a pulmonary hypertension condition

#2018
20170136014
2017-05-18

Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor and/or a JAK-2 inhibitor

#2019
20170130222
2017-05-11

Small molecules that enhance the activity of oligonucleotides

#2020
20170129902
2017-05-11

PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-alpha]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF

#2021
20170128445
2017-05-11

Fused imidazole and pyrazole derivatives as modulators of TNF activity

#2022
20170128444
2017-05-11

POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE

#2023
20170128443
2017-05-11

Polycyclic-carbamoylpyridone compounds and their pharmaceutical use

#2024
20170119764
2017-05-04

Polycyclic-carbamoylpyridone compounds and their pharmaceutical use

#2025
20170119763
2017-05-04

Combinations

#2026
20170114064
2017-04-27

Fused triazole derivatives as phosphodiesterase 10A inhibitors

#2027
20170114030
2017-04-27

COMPOSITION WITH HIGH CONTENT OF CYCLIC DIPEPTIDE

#2028
20170112836
2017-04-27

Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions

#2029
20170107209
2017-04-20

Inhibitors of Jun N-terminal kinase

#2030
20170101396
2017-04-13

Quinoxaline derivatives useful as FGFR kinase modulators

#2031
20170100413
2017-04-13

COMPOSITION FOR REDUCING THE FREQUENCY OF URINATION, METHOD OF MAKING AND USE THEREOF

#2032
20170100406
2017-04-13

Combinations of an FGFR inhibitor and an IGF1R inhibitor

#2033
20170100396
2017-04-13

PYRROLOPYRAZINE DERIVATIVES FOR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA

#2034
20170096428
2017-04-06

Cyclopropabenzofuranyl pyridopyrazinediones

#2035
20170095490
2017-04-06

Imidazopyridines Syk inhibitors

#2036
20170095472
2017-04-06

N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists

#2037
20170095471
2017-04-06

Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor

#2038
20170087164
2017-03-30

METHOD AND COMPOSITION FOR ENHANCEMENT OF MALE ERECTILE FUNCTION

#2039
20170081331
2017-03-23

Pyrazolopyrazines and their use in the treatment, amelioration or prevention of a viral disease

#2040
20170079982
2017-03-23

Antiviral therapy

#2041
20170073356
2017-03-16

Pyridone and aza-pyridone compounds and methods of use

#2042
20170073347
2017-03-16

Heterocyclyl-butanamide derivatives

#2043
20170071962
2017-03-16

Therapeutic Combinations of a Proteasome Inhibitor and a BTK Inhibitor

#2044
20170071945
2017-03-16

Method of treating insomnia

#2045
20170065583
2017-03-09

Treatment of cancer with dihydropyrazino-pyrazines

#2046
20170065545
2017-03-09

Compositions and methods for the reduction or prevention of hepatic steatosis

#2047
20170049974
2017-02-23

Heating unit for use in a drug delivery device

#2048
20170049778
2017-02-23

Treatment of erectile dysfunction and other indications

#2049
20170049771
2017-02-23

Targeting PARP1 for treatment of TSC and cancers

#2050
20170046477
2017-02-16

Determination of NFkB pathway activity using unique combination of target genes

#2051
20170044132
2017-02-16

Heterocyclic compound

#2052
20170042922
2017-02-16

Sitagliptin tannate complex

#2053
20170042911
2017-02-16

PHARMACEUTICAL FORMULATIONS AND USES THEREOF IN THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION

#2054
20170042890
2017-02-16

METHODS OF REDUCING DECLINE IN VITAL CAPACITY

#2055
20170037060
2017-02-09

Substituted [1,2,4]triazolo[1,5-a]pyrazines as phosphodiesterase inhibitors

#2056
20170037048
2017-02-09

Organic compounds

#2057
20170035881
2017-02-09

Therapeutic Combinations of an IRAK4 Inhibitor and a BTK Inhibitor

#2058
20170035775
2017-02-09

Quinoxaline derivatives as GPR6 modulators

#2059
20170035770
2017-02-09

Treatment of erectile dysfunction and other indications

#2060
20170035756
2017-02-09

Methods of blocking the CXCR-4/SDF-1 signaling pathway with inhibitors of bruton's tyrosine kinase

#2061
20170035755
2017-02-09

Syk inhibitors

#2062
20170035751
2017-02-09

AZA spiro alkane derivatives as inhibitors of metalloproteases

#2063
20170029438
2017-02-02

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

#2064
20170029428
2017-02-02

Crystal forms of ()-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-]pyrazin-1-yl)--(pyridin-2-yl)benzamide

#2065
20170027942
2017-02-02

Treatment of erectile dysfunction and other indications

#2066
20170027934
2017-02-02

Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor

#2067
20170027933
2017-02-02

Pharmaceutical compositions

#2068
20170027932
2017-02-02

Treatment of cancer with TOR kinase inhibitors

#2069
20170022191
2017-01-26

Benzamides

#2070
20170020955
2017-01-26

Anthelmintic combinations and methods of use thereof

#2071
20170020871
2017-01-26

Bromocriptine formulations

#2072
20170020869
2017-01-26

Neuroprotective bicyclic compounds and methods for their use in treating autism spectrum disorders and neurodevelopmental disorders

#2073
20170020868
2017-01-26

Treatment for diabetes in patients inappropriate for metformin therapy

#2074
20170014436
2017-01-19

Oral formulations Mimetic of Roux-en-Y gastric bypass actions on the ileal brake; Compositions, Methods of Treatment, Diagnostics and Systems for treatment of metabolic syndrome manifestations including insulin resistance, fatty liver disease, hyperlipidemia, and type 2 diabetes.

#2075
20170014420
2017-01-19

Use of NK-1 receptor antagonists for treating hypomagnesemia, neurogenic inflammation, and cardiac dysfunction associated with EGFR-blocking drugs

#2076
20170014410
2017-01-19

Treatment of proliferative disorders with a chemiluminescent agent

#2077
20170008899
2017-01-12

BTK Inhibitors

#2078
20170007603
2017-01-12

Liver X receptor modulators

#2079
20170006894
2017-01-12

Chewable composition

#2080
20170002016
2017-01-05

Azaspiro derivatives as TRPM8 antagonists

#2081
20170002010
2017-01-05

Imidazopyrazinone derivatives

#2082
20170001997
2017-01-05

Oxepan-2-yl-pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use

#2083
20170001983
2017-01-05

TRPA1 modulators

#2084
20170000788
2017-01-05

Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease

#2085
20160376280
2016-12-29

Substituted 7-azabicycles and their use as orexin receptor modulators

#2086
20160376277
2016-12-29

Heterocyclic compounds

#2087
20160375019
2016-12-29

TREATMENT OF CHRONIC GRAFT VERSUS HOST DISEASE WITH SYK INHIBITORS

#2088
20160375018
2016-12-29

Method of preparing very slightly soluble drug with solid dosage form

#2089
20160374994
2016-12-29

Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof

#2090
20160367564
2016-12-22

Pharmaceutical compound

#2091
20160367552
2016-12-22

Pharmaceutical compositions of sitagliptin

#2092
20160362439
2016-12-15

Cyclic peroxides as prodrugs for selective delivery of agents

#2093
20160361380
2016-12-15

COMBINATION COMPOSITIONS FOR TREATING DISORDERS REQUIRING REMOVAL OR DESTRUCTION OF UNWANTED CELLULAR PROLIFERATIONS

#2094
20160361375
2016-12-15

Inhibitors of hepatitis C virus

#2095
20160361353
2016-12-15

NITRIC OXIDE GENERATOR COMBINED WITH PDE5 INHIBITORS

#2096
20160354380
2016-12-08

Treatment of genotyped diabetic patients with DPP-IV inhibitors such as linagliptin

#2097
20160354379
2016-12-08

Compounds and compositions for treating chemical warfare agent-induced injuries

#2098
20160346290
2016-12-01

Use of Sigma-1 receptor agonist compounds

#2099
20160346289
2016-12-01

Fixed-Dose Combinations of Antiviral Compounds

#2100
20160346280
2016-12-01

COMPOSITIONS AND METHODS OF TREATING PULMONARY HYPERTENSION