21042 ⎘
Medicinal preparations containing peptides; Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof; Enzymes; Proenzymes; Derivatives thereof; Hydrolases (3) acting on peptide bonds (3.4) Metalloendopeptidases (3.4.24), e.g. collagenase
REDUCTION OF ADIPOSE TISSUE
#302COMPOSITIONS AND METHODS FOR TREATING FIBROTIC MYOPATHY CONDITIONS USING COLLAGENASE
#303ADAM10 INHIBITION TO TREAT FRAGILE X SYNDROME
#304Modulation of muscle and adipocyte distribution and fate
#305Methods for treating cellulite
#306Methods and compositions for the identification and treatment of individuals having or likely to develop short stature
#307Methods and compositions for enhancing intranasal delivery of therapeutic agents
#308Inhibitors of endoglin activity for the treatment of fibrosis
#309ANTIMICROBIAL COMPOSITION COMPRISING PYROGENIC SILICA AND SERRATHOPEPTIDASE AND USES THEREOF
#310Treatment and Prophylaxis for Parkinson's Disease
#311METHOD OF TREATING FIBROPROLIFERATIVE DISORDERS INCLUDING DUPUYTREN'S DISEASE WITH ONE OR MORE SPECIFIC HUMAN MATRIX METALLOPROTEINASE AND A TNF ANTAGONIST
#312Amniotic membrane preparations and purified compositions and anti-inflammation methods
#313Cytolethal distending toxin subunit B conjugated or fused to toxin lethal factor
#314GENE THERAPY VECTOR FOR TREATMENT OF STEROID GLAUCOMA
#315Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
#316Purified amniotic membrane compositions and methods of use
#317Contact lens use in the treatment of an ophthalmologic condition
#318Treatment and prophylaxis for gastroesophageal reflux disease
#319Pharmaceutical composition based on Centella asiatica (L.) for the treatment of lower limb ulcers
#320MATRIX METALLOPROTEINASSES AND USES THEREOF
#321Treatment of Peyronie's disease
#322Methods for the Treatment and the Prognostic Assessment of Malignant Pleural Mesothelioma
#323COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE
#324PHARMACEUTICAL COMPOUNDING KIT
#325Method of treatment for pulpitis and/or enhancement for dentinogenesis
#326Dissolvable gel-forming film for delivery of active agents
#327THERMOSENSITIVE HYDROGEL COLLAGENASE FORMULATIONS
#328COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES
#329Methods and systems for toxin delivery to the nasal cavity
#330Method of treating fibrosis in skeletal muscle tissue
#331Pharmaceutical composition comprising botulinum, a non ionic surfactant, sodium chloride and sucrose
#332System and Method for Modulation of Cardiac Tissue
#333Mixture of betamethasone and tranilast with a transdermal gel for scar treatment
#334Antimicrobial composition comprising pyrogenic silica and serrathiopeptidase and uses thereof
#335PROTEASE COMPOSITIONS FOR THE TREATMENT OF DAMAGED TISSUE
#336TISSUE REGENERATION PROMOTING AGENT
#337Fusion proteins of collagen-binding domain and parathyroid hormone
#338Diffusible factors and cancer cells
#339Stable thermolysin hydrogel
#340Use of collagenase to treat glaucoma
#341Peptide directed protein knockdown
#342Enhanced staphylolytic activity of the bacteriophage vBSauS-philPLA88 virion-associated peptidoglycan hydrolase HydH5: fusions, deletions and synergy with LysH5
#343Chimeric polypeptides and their use in bacterial decolonization
#344Therapy with enterotoxin to treat ovarian and uterine cancer
#345Method for stimulating or enhancing proliferation of cells by activating the mucin 1 (MUC1) receptor
#346Treatment of ophthalmic conditions
#347Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof
#348Use of proteases for gluten intolerance
#349Multimodal antimicrobial therapy
#350Ultra-Low Dose Lysostaphin for Treating MRSA
#351Methods for Treating Adhesive Capsulitis
#352Cosmetic and pharmaceutical composition with modified olygopeptides in form of supramolecular assembly
#353Exfoliative hair retention-promoting formulation
#354Animal product-free culture medium and a process for producing a supernatant of clostridium comprising one or more collagenolytic and gelatinolytic proteases
#355Variants of TACE pro-domain as TNF-A inhibitor and their medical use
#356Mutants of staphylokinase carrying amino and carboxy-terminal extensions for polyethylene glycol conjugation
#357Pharmaceutical removal of neuronal extensions from a degenerating disc
#358Treatment of pulmonary vascular remodeling with neprilysin
#359Gelatinase inhibitors and prodrugs
#360Systems, compositions, and methods for transplantation and treating conditions
#361METHODS FOR MODIFICATION OF TISSUES
#362Devices and methods for reducing the appearance of cellulite
#363BMP Peptides & Methods of Use
#364Process for the production and purification of the collagenase enzyme from vibrio alginolyticus
#365ADAMTS-13 mutant
#366Methods for extracting a tooth
#367Gain-of-function ADAMTS13 variants resistant to auto antibody inhibition and methods of use thereof
#368Methods of Treating Serosal Cancer
#369Pharmaceutical formulations of xanthine or xanthine derivatives, and their use
#370Combination therapy for the treatment of cancer using an anti-C-met antibody
#371Clostridium histolyticum enzymes and methods for the use thereof
#372ADAM12 inhibitors and their use against inflammation-induced fibrosis
#373ALTERING PROTEIN CONCENTRATIONS IN CEREBROSPINAL FLUID AND/OR BRAIN INTERSTITIAL FLUID
#374Pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
#375DERMASEPTIN B2 USED AS AN INHIBITOR OF THE GROWTH OF A TUMOR
#376PHARMACEUTICAL PRODUCT FOR PREVENTING OR TREATING ALZHEIMER'S DISEASE
#377INACTIVATION OF SMOOTH MUSCLE TISSUE
#378Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone
#379Method of Treating or Reducing EFP
#380USE OF ALFIMEPRASE IN THE TREATMENT OF THROMBOSIS
#381Pharmaceutical compositions and methods for digesting atherosclerotic plaques
#382Compositions and methods for enhancing penetration of biologically active substances into tissues or organs
#383Fungal-specific metalloproteases and uses thereof
#384Treatment of carpal tunnel syndrome by injection of the flexor retinaculum
#385Treatment method and product for uterine fibroids using purified collagenase
#386REAGENTS AND METHODS FOR DETECTING PNH TYPE II WHITE BLOOD CELLS AND THEIR IDENTIFICATION AS RISK FACTORS FOR THROMBOTIC DISORDERS
#387Proteomic IPF markers
#388Treatment method and product for uterine fibroids using purified collagenase
#389Subcutaneous administration of ADAMTS13
#390Treatment of ophthalmic conditions
#391METHODS FOR IMPROVING GUT HEALTH
#392Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof
#393Cell therapy for the treatment of neurodegeneration
#394Fibrinolytic/Proteolytic Treatment of Myofacial and Neuropathic Pain and Related Conditions
#395Use of alginate oligomers in combating biofilms
#396Use of matrix metalloproteinase inhibitors to treat tuberculosis
#397Treatment of carpal tunnel syndrome by injection of the flexor retinaculum
#398Stabilized liquid and lyophilized ADAMTS13 formulations
#399Flexible tissue matrix and methods for joint repair
#400Methods and compositions for enhancing intranasal delivery of therapeutic agents
#401Method of peptide hydrolysis, peptidase, the composition for use as a bacteriostatic and bactericidal agent, a kit and the uses of the active form of LytM from or derivatives thereof
#402Metalloproteinase-9 oligopeptides and their therapeutic use
#403Treatment of ophthalmic conditions
#404Methods of treatment with elastase
#405COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES
#406Methods for Treating Adhesive Capsulitis
#407Method of isolating cells from a tissue in a mammal
#408Treatment and prophylaxis for obsessive compulsive disorder
#409Flowable implant with crosslinkable surface membrane
#410Collagenase G and Collagenase H compositions for the treatment of diseases involving alterations of collagen
#411Amniotic membrane preparations and purified compositions and anti-inflammation methods
#412Functionalized tissue matrices
#413Methods of degrading or inhibiting botulinum neurotoxin using designer ubiquitin ligases
#414Enzyme-activated collagen and tissue matrices
#415Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
#416Purified amniotic membrane compositions and methods of use
#417Methods of Treating Cancer Using Growth Factor Retargeted Endopeptidases
#418Pharmaceutical Compositions and Methods for Digesting Atherosclerotic Plaques
#419COMPOSITIONS AND METHODS FOR INHIBITING VIRAL INFECTION
#420Methods of preventing ischemia/reperfusion damage to kidney using antibodies that bind BMP-1 isoforms
#421COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE
#422ENDOPEPTIDASE AND NEUROTOXIN COMBINATION TREATMENT OF BLADDER DISORDERS
#423PROTEASE ENZYMES FOR INCREASED PROTEIN DIGESTION RATE AND ABSORPTION AND METHODS OF USING THE SAME
#424ENDOMETRIAL STEM CELLS AND METHODS OF MAKING AND USING SAME
#425ADAMTS13-containing compositions having thrombolytic activity
#426Enhanced staphylolytic activity of the bacteriophage vBSauS-philPLA88 virion-associated peptidoglycan hydrolase HydH5: fusions, deletions and synergy with LysH5
#427Wound healing peptides and methods of use thereof
#428TISSUE FUSION METHOD USING COLLAGENASE FOR REPAIR OF SOFT TISSUE
#429Gelatinase inhibitors and prodrugs
#430Enzymatic wound debriding compositions with enhanced enzymatic activity
#431REAGENTS AND METHODS FOR DETECTING PNH TYPE II WHITE BLOOD CELLS AND THEIR IDENTIFICATION AS RISK FACTORS FOR THROMBOTIC DISORDERS
#432Immunotherapy against several tumors including gastrointestinal and gastric cancer
#433Use of proteases for gluten intolerance
#434COMPOSITIONS AND METHODS FOR INHIBITING MMP-9-MEDIATED CELL MIGRATION
#435METALLOPROTEINASE OLIGOPEPTIDES AND THEIR THERAPEUTIC USE
#436Chimeric polypeptides and their use in bacterial decolonization
#437Amniotic membrane preparations and purified compositions and anti-inflammation methods
#438Hatching fluid enzymes and uses thereof
#439PHARMACEUTICAL COMPOSITION FOR TREATING THE GASTROINTESTINAL TRACT
#440COMPOSITIONS, TARGETS, METHODS AND DEVICES FOR THE THERAPY OF OCULAR AND PERIOCULAR DISORDERS
#441Purified amniotic membrane compositions and methods of use
#442Compositions and methods for regulating SAS1R
#443Methods of modulating TGFβ signaling
#444Use and application of a pharmaceutical composition containing a mixture of natural-origin heterocyclical guanidine
#445Compositions and methods for producing clostridial collagenases
#446Fusion proteins
#447Treatment of Sleep Disordered Breathing with Neurotoxin
#448ADAM12 Inhibitors and Their Use Against Inflammation-Induced Fibrosis
#449Methods for improving gut health
#450Fast acting SNARE-cleaving enzymes
#451Reduced-pressure treatment systems and methods employing debridement mechanisms
#452Reduced-pressure treatment systems and methods employing debridement mechanisms
#453Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
#454Implantable matrix having optimum ligand concentrations
#455Cosmetic and pharmaceutical compositions having modified proteins in the form of a supramolecular assembly
#456Treatment of pain
#457DERMASEPTIN B2 USED AS AN INHIBITOR OF THE GROWTH OF A TUMOR
#458Non-cytotoxic protein conjugates
#459Treatment of Peyronies disease
#460CLOSTRIDIAL TOXIN DERIVATIVES ABLE TO MODIFY PERIPHERAL SENSORY AFFERENT FUNCTIONS
#461Treatment of pulmonary vascular remodeling with neprilysin
#462Inhibition of secretion from non-neuronal cells
#463LOCAL DEHYDRATION FOR CARPAL TUNNEL SYNDROME
#464Methods and systems for toxin delivery to the nasal cavity
#465Therapy with enterotoxin to treat ovarian and uterine cancer
#466ORAL COMPOSITION AND METHOD OF FORMING AND USING SAME
#467ADAMTS-13 mutant
#468METHODS AND COMPOSITIONS FOR PROMOTING WOUND HEALING
#469PROSTHETIC IMPLANT SHELL
#470Apparatus and methods for enzymatic debridement of skin lesions
#471Pharmaceutical composition containing arazyme for the prevention of liver dysfunction
#472Composition containing arazyme for the prevention and treatment of cancer
#473Treatment of ocular diseases
#474Membrane type-1 matrix metalloprotein inhibitors and uses thereof
#475GENE THERAPY VECTOR FOR TREATMENT OF STEROID GLAUCOMA
#476Methods for the treatment and the prognostic assessment of malignant pleural mesothelioma
#477CATABOLIC AGENTS
#478SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME
#479METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE
#480COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES
#481Compositions and Methods for Treating Collagen-Mediated Diseases
#482Compositions and Methods for Treating Collagen-Mediated Diseases
#483Compositions and Methods for Treating Collagen-Mediated Diseases
#484Immunotherapy against several tumors including gastrointestinal and gastric cancer
#485Stabilized liquid and lyophilized ADAMTS13 formulations
#486TEMPERATURE SENSITIVE MUTANTS OF MATRIX METALLOPROTEASES AND USES THEREOF
#487Polymerized Hemoglobin Media And Its Use In Isolation And Transplantation of Islet Cells
#488USE OF PROTEASES FOR GLUTEN INTOLERANCE
#489Compositions and Methods for Treating Collagen-Mediated Diseases
#490Compositions and Methods for Treating Collagen-Mediated Diseases
#491Inactivation of smooth muscle tissue
#492Methods of prolonging patency of hemodialysis access
#493Compositions and methods comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions
#494Methods comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions
#495Methods comprising serratia peptidase for inhibition of osteomyelitis
#496Compositions and methods comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions
#497Compositions and methods comprising serratia peptidase for inhibition of bacterial vaginosis, bacterial vaginitis or fungal vaginitis
#498METHOD OF TREATING HEARING LOSS USING XIAP
#499COMPOSITIONS AND METHODS COMPRISING SERRATIA PEPTIDASE FOR INHIBITION AND TREATMENT OF BIOFILMS RELATED TO CERTAIN CONDITIONS
#500COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES
#501INHIBITION OF SECRETION FROM NON-NEURONAL CELLS
#502Frozen compositions and methods for piercing a substrate
#503Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
#504Antimicrobial Coating for Surgical Implants and Method of Use
#505Dye conjugates of template-fixed peptidomimetics
#506Treatment of obesity and related disorders
#507Methods of comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions
#508Wound healing peptides and methods of use thereof
#509Renal tissue regeneration
#510FUSION PROTEINS
#511Use of matrix metalloproteinase-10 (MMP-10) for thrombolytic treatments
#512Methods of novel therapeutic candidate identification through gene expression analysis in vascular-related diseases
#513Treatment/Cure of Autoimmune Disease
#514BMP-1 PROCOLLAGEN C-PROTEINASE FOR DIAGNOSIS AND TREATMENT OF BONE AND SOFT TISSUE DEFECTS AND DISORDERS
#515Multivalent clostridial toxins
#516Methods of Treating Cancer Using Growth Factor Retargeted Endopeptidases
#517Cell membrane translocation of regulated snare inhibitors, compositions therefor, and methods for treatment of disease
#518COMPOSITIONS FOR TREATMENT WITH METALLOPEPTIDASES, METHODS OF MAKING AND USING THE SAME
#519MEDICAMENT, DENTAL MATERIAL, AND METHOD OF SCREENING
#520APHERESIS, ADMINISTRATION OF AGENT, OR COMBINATION THEREOF
#521NOVEL USES FOR 4-PHENYLBUTYRATE (4PBA) AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
#522Method and compositions for prevention and treatment of diabetic and aged skin
#523HYBRID TETNUS TOXOID PROTEINS THAT MIGRATE RETROGRADELY AND TRANSYNAPTICALLY INTO THE CNS
#524THERAPEUTIC PREPARATIONS CONTAINING WHARTON'S JELLY
#525COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES
#526PHARMACEUTICAL COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION OF LIVER DYSFUNCTION
#527Use of alginate oligomers in combating biofilms
#528Antimicrobial composition comprising pyrogenic silica and serratiopeptidase
#529Temperature sensitive mutants of matrix metalloproteases and uses thereof
#530Composition Containing Arazyme for the Prevention and Treatment of Arthritis
#531Methods for identifying areas of a subject's skin that appear to lack volume
#532Therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin
#533Treatment of carpal tunnel syndrome by injection of the flexor retinaculum
#534Pericellular Collagenase Directs the 3-Dimensional Development of White Adipose Tissue
#535Hybrid proteins that migrate retrogradely and transynaptically into the CNS
#536COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES
#537REDUCTION OF ADIPOSE TISSUE
#538GASTROPOD BIOLOGICAL FLUID, METHOD OF MAKING AND REFINING AND USE
#539Mutants of Staphylokinase Carrying Amino and Carboxy-Terminal Extensions for Polyethylene Glycol Conjugation
#540Methods for the treatment and prevention of diseases of biological conduits
#541Systems, devices, and methods for making or administering frozen particles
#542Systems, devices, and methods for making or administering frozen particles
#543COMPOSITIONS AND METHODS FOR REGULATING SAS1R
#544Systems, devices, and methods for making or administering frozen particles
#545Systems, devices, and methods for making or administering frozen particles
#546Reduced-pressure treatment systems and methods employing debridement mechanisms
#547Methods for identifying areas of a subject's skin that appear to lack volume
#548Systems, devices and methods for making or administering frozen particles
#549Frozen compositions and methods for piercing a substrate
#550Frozen compositions and methods for piercing a substrate
#551Fusion proteins of collagen-binding domain and parathyroid hormone
#552Frozen compositions and methods for piercing a substrate
#553Frozen compositions and array devices thereof
#554Frozen compositions and methods for piercing a substrate
#555Frozen piercing implements and methods for piercing a substrate
#556Frozen compositions and methods for piercing a substrate
#557Methods and systems for toxin delivery to the nasal cavity
#558Method of Treating Peyronie's Disease
#559USE OF MATRIX METALLOPROTEINASE-10 (MMP-10) FOR THROMBOLYTIC TREATMENTS
#560TREATMENT OF PAIN
#561Methods and Compositions for Treating Migraine Pain
#562Lys K endolysin is synergistic with lysostaphin against MRSA
#563Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
#564Designer ubiquitin ligases having a non-cleavable SNAP25 domain and E3-ligase domain
#565VON WILLEBRAND FACTOR (VWF) INHIBITORS FOR TREATMENT OR PREVENTION OF INFARCTION
#566COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION AND TREATMENT OF CANCER
#567NOVEL COMPOSITIONS FOR PREVENTION AND TREATMENT OF MASTITIS AND METRITIS
#568Therapeutic Peptide Compositions And Methods Of Making And Using Same
#569Method of Treatment of Inflammatory Diseases
#570Therapy with clostridium perfringens enterotoxin to treat ovarian and uterine cancer
#571Methods and compounds for the treatment of mucus hypersecretion
#572ENZYME MEDIATED DELIVERY SYSTEM
#573Hybrid tetanus toxoid proteins that migrate retrogradely and transynaptically into the CNS
#574Pharmaceutical Composition For Treating Vascular-Related Diseases Comprising Peptide
#575Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
#576AGENTS FOR IMPROVING INFLAMMATORY BOWEL DISEASE
#577BMP-1 procollagen c-proteinase for diagnosis and treatment of bone and soft tissue defects and disorders
#578USE OF BOTULINUM TOXIN FOR PORLONGED LOCAL DESENSITIZATION
#579DIETARY ANTI-BACTERIAL COMPOSITIONS
#580Series spring blade tensioner
#581Claudins as markers for early detection, diagnosis, prognosis and as targets of therapy for breast and metastatic brain or bone cancer
#582Clostridial toxin derivatives able to modify peripheral sensory afferent functions
#583Anti-microbial compositions comprising a cationic peptide and a glycylglycine endopeptidase
#584Methods for treating adhesive capsulitis
#585METHODS OF TREATING CHRONIC NEUROGENIC INFLAMMATION USING MODIFIED CLOSTRIDIAL TOXINS
#586LHRH ANTAGONISTS FOR THE TREATMENT OF LOWER URINARY TRACT SYMPTOMS
#587Use of collagenase to facilitate guide wire crossing in total arterial occlusions
#588Methods and compositions for promoting wound healing
#589Methods for using tetanus toxin for beneficial purposes in animals (mammals)
#590System comprising elastase
#591Methods for enlarging the lumen of an obstructed biological conduit
#592ENDOMETRIAL STEM CELLS AND METHODS OF MAKING AND USING SAME
#593Multivalent clostridial toxins
#594Composition exhibiting a von Willebrand Factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
#595Method for treating lateral epicondylitis using collagenase
#596Compositions for Topical Enzymatic Debridement
#597Clostridial toxin derivatives able to modify peripheral sensory afferent functions
#598Methods for enlarging the diameter of a biological conduit in a human subject
#599Anti-Inflammatory Peptides and Methods of Use Thereof
#600Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition