ClassID:

21042

A61K38/4886 - CPC Classification

Classification description:

Medicinal preparations containing peptides; Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof; Enzymes; Proenzymes; Derivatives thereof; Hydrolases (3) acting on peptide bonds (3.4) Metalloendopeptidases (3.4.24), e.g. collagenase

Sub-classes:
Recent Application in this class:
#1
20260137762
2026-05-21

Method of Chemically Loosening Adhesions and Kit for Same

#2
20260115264
2026-04-30

THERMOSENSITIVE HYDROGEL COLLAGENASE FORMULATIONS

#3
20260115147
2026-04-30

DISSOLVABLE GEL-FORMING FILM FOR DELIVERY OF ACTIVE AGENTS

#4
20260115120
2026-04-30

COMPOSITION FOR INHIBITING LIPOFUSCIN ACCUMULATION OR REMOVING LIPOFUSCIN CONTAINING METALLOPROTEASE DERIVED FROM A STRAIN OF THE GENUS CHRYSEOBACTERIUM

#5
20260102359
2026-04-16

COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION

#6
20260097085
2026-04-09

AMNIOTIC FLUID COMPOSITION AND METHOD OF USING

#7
20260092101
2026-04-02

METHOD FOR TREATING SEPSIS AND RELATED DISEASES

#8
20260091093
2026-04-02

Methods Of Treating Plantar Fibromatosis

#9
20260091092
2026-04-02

Methods Of Treating Plantar Fibromatosis

#10
20260091058
2026-04-02

ENHANCED MACROPHAGES

#11
20260069665
2026-03-12

SYSTEMS AND METHODS FOR EPICARDIAL TISSUE DISTENSION SOLUTIONS

#12
20260048102
2026-02-19

IMMUNOMODULATORY COMPOSITIONS AND METHODS

#13
20260041716
2026-02-12

PHARMACEUTICAL COMPOSITION FOR TREATING WOUND REPAIR AND PREPARATION METHOD THEREOF

#14
20260034199
2026-02-05

Methods Of Treating Plantar Fibromatosis

#15
20260034067
2026-02-05

Treatment Method and Product for Uterine Fibroids using Purified Collagenase

#16
20260021169
2026-01-22

CO-TRANSPLANTATION OF MMP-9 ENHANCED MESENCHYMAL STEM CELLS AND PANCREATIC ISLETS FOR THE TREATMENT OF DIABETES

#17
20260014236
2026-01-15

ACTIVATORS OF COAGULATION FACTOR X AND FORMULATIONS THEREOF FOR TREATING BLEEDING DISORDERS

#18
20250387459
2025-12-25

Method of Using r-SAK Prior to Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction

#19
20250361499
2025-11-27

Thrombolytic Protease Resistant ADAMTS13 Mutants

#20
20250352450
2025-11-20

METHOD OF ASSESSING AND TREATING CELLULITE

#21
20250339375
2025-11-06

Treatment Method and Product for Uterine Fibroids using Purified Collagenase

#22
20250302744
2025-10-02

NOVEL LIQUID FORMULATION FOR PLASMA PROTEIN

#23
20250281581
2025-09-11

METHODS OF CANCER TREATMENT BY INTRATUMORAL INJECTION OF MUTANT COLLAGENASE

#24
20250249080
2025-08-07

COLLAGENASE FORMULATIONS AND METHODS OF PRODUCING THE SAME

#25
20250244326
2025-07-31

BLOOD BIOMARKERS IN LONG-COVID-19

#26
20250242003
2025-07-31

Treatment Of Uterine Fibroids Using Purified Collagenase

#27
20250242002
2025-07-31

TRUNCATED FORMS OF IGA PROTEASE, FUSION PROTEINS COMPRISING A TRUNCATED FORM OF IGA PROTEASE AND USES THEREOF

#28
20250228875
2025-07-17

METHODS OF TREATING, AMELIORATING AND/OR PREVENTING FIBRODYSPLASIA OSSIFICANS PROGRESSIVA AND HETEROTOPIC OSSIFICATION, AND KITS FOR THE SAME

#29
20250222080
2025-07-10

CLOSTRIDIUM HISTOLYTICUM ENZYMES AND METHODS FOR THE USE THEREOF

#30
20250213661
2025-07-03

ENHANCED DELIVERY OF ANTIOXIDANTS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS INVOLVING OXIDATIVE STRESS

#31
20250207119
2025-06-26

METHODS AND COMPOSITIONS FOR INHIBITING ADAM10 BIOLOGICAL ACTIVITIES

#32
20250188434
2025-06-12

METHODS AND COMPOSITIONS FOR INHIBITING ADAM9 BIOLOGICAL ACTIVITIES

#33
20250177497
2025-06-05

NOVEL BACTERIA-BASED DELIVERY SYSTEM FOR TACE (ADAM17) SELECTIVE BIOLOGICAL INHIBITOR

#34
20250177455
2025-06-05

NOVEL THERAPEUTIC COMPRISING A SECRETOME FROM MESENCHYMAL STEM CELLS OF UMBILICORD TISSUE OR WHARTON'S JELLY

#35
20250152627
2025-05-15

COMPOSITIONS AND METHODS FOR ENHANCING IMMUNE CELL FUNCTION USING MODIFIED CELLS WITH GLYCOCALYX EDITING ENZYMES

#36
20250143933
2025-05-08

ENDOSCOPIC, PERCUTANEOUS AND OTHER METHODS FOR DISSOLUTION OF PANCREATIC NECROSIS

#37
20250134819
2025-05-01

ORAL DOSAGE FORM WITH A GASTRO RESISTANT CAPSULE SHELL

#38
20250099559
2025-03-27

STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS

#39
20250073280
2025-03-06

CORYNEBACTERIUM TO TREAT OR LIMIT CUTANEOUS WOUND INFECTION

#40
20250073278
2025-03-06

METHODS AND COMPOSITIONS FOR TREATMENT OF PENILE DEFECTS

#41
20250049897
2025-02-13

METHODS, APPARATUSES AND SYSTEMS FOR ADOLESCENT IDIOPATHIC SCOLIOSIS TREATMENT

#42
20250041391
2025-02-06

Pharmaceutical compositions comprising collagenase I and collagenase II

#43
20250002891
2025-01-02

ENDOTOXIN-REDUCED THERMOLYSIN

#44
20250002890
2025-01-02

COMPOSITIONS AND METHODS FOR PRODUCING CLOSTRIDIAL COLLAGENASES

#45
20240409910
2024-12-12

RECOMBINANT POLYPEPTIDE FOR USE AS A MEDICINE, ANTISEPTIC AGENT, ANTIBACTERIAL AGENT, ANTI-INFLAMMATORY AGENT, COMPOSITIONS COMPRISING IT AND USES THEREOF

#46
20240400641
2024-12-05

Nanoparticles Having Molecules That Bind or Block PD-L1 and Uses In Treating Cancer

#47
20240398912
2024-12-05

METHOD OF MITIGATION OF INJURIES CAUSED BY SYSTEMIC GENOTOXIC STRESS

#48
20240392275
2024-11-28

LYSOSTAPHIN VARIANTS AND METHODS OF USE THEREOF

#49
20240382570
2024-11-21

STABLE THERMOLYSIN HYDROGEL

#50
20240382433
2024-11-21

DISSOLVABLE GEL-FORMING FILM FOR DELIVERY OF ACTIVE AGENTS

#51
20240344047
2024-10-17

MODIFIED RECOMBINANT COLLAGENASE, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF IN DENTAL RELATED PROCEDURES

#52
20240325318
2024-10-03

SOLUBILIZATE WITH AT LEAST ONE CANNABINOID

#53
20240299508
2024-09-12

COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES

#54
20240299507
2024-09-12

HUMANIZED ANTI-MUC1* ANTIBODIES AND DIRECT USE OF CLEAVAGE ENZYME

#55
20240271092
2024-08-15

Methods of Treating Cancer and Infectious Diseases Using Cell Based Therapies

#56
20240269245
2024-08-15

NUCLEIC ACID MOLECULES ENCODING CLOSTRIDIUM HISTOLYTICUM COLLAGENASE I AND METHODS OF PRODUCING THE SAME

#57
20240261377
2024-08-08

USE OF CLOSTRIDIUM HISTOLYTICUM PROTEASE MIXTURE IN PROMOTING WOUND HEALING

#58
20240252602
2024-08-01

Clostridium Histolyticum Enzymes And Methods For The Use Thereof

#59
20240238390
2024-07-18

PEPTIDES FOR THE TREATMENT OF CANCER AND/OR METASTASIS

#60
20240216485
2024-07-04

METHOD OF TREATING OR REDUCING EFP

#61
20240216297
2024-07-04

Solubilizate with curcumin and optionally at least one other active substance

#62
20240197912
2024-06-20

A PHARMACEUTICALLY ACCEPTABLE AQUEOUS GEL COMPOSITION FOR MRNA DELIVERY

#63
20240165211
2024-05-23

Treatment Of Uterine Fibroids Using Purified Collagenase

#64
20240159751
2024-05-16

DIAGNOSTIC AGENT AND MEDICINE COMPRISING ADAMTS13 AS MAIN INGREDIENT

#65
20240156922
2024-05-16

FUNGAL PROTEASE MIXTURES AND USES THEREOF

#66
20240082164
2024-03-14

Treatment Method and Product for Uterine Fibroids using Purified Collagenase

#67
20240067947
2024-02-29

TRUNCATED MODIFIED RECOMBINANT ADAMTS13 AND USES THEREOF

#68
20240058428
2024-02-22

COMPOSITION FOR TREATING OR PREVENTING MYOPATHY, OBESITY OR DIABETES

#69
20240041993
2024-02-08

Collagenase formulations and methods of producing the same

#70
20240041992
2024-02-08

COMPOSITIONS FOR REMODELING EXTRACELLULAR MATRIX AND METHODS OF USE THEREOF

#71
20240041827
2024-02-08

COMPOSITIONS FOR THE TREATMENT OF FAT RELATED CONDITIONS AND DISORDERS

#72
20240041744
2024-02-08

METHOD OF ASSESSING AND TREATING CELLULITE

#73
20230416717
2023-12-28

Nucleic acid molecules encoding clostridium histolyticum collagenase II and methods of producing the same

#74
20230405097
2023-12-21

METHODS OF REDUCING COLLAGENASE-MEDIATED BRUISING IN A SUBJECT HAVING CELLULITE

#75
20230405096
2023-12-21

ADAMTS13 VARIANT HAVING INCREASED ESCAPING RATE OR ACTIVITY AGAINST AUTOANTIBODY

#76
20230382971
2023-11-30

Nanoparticles having molecules that bind or block PD-L1 and uses in treating cancer

#77
20230355726
2023-11-09

FIBRINOLYTIC ENZYME COMPOSITION FOR FIBROSIS TREATMENT

#78
20230346898
2023-11-02

USE OF THERMOLYSIN TO REDUCE OR ELIMINATE BACTERIAL BIOFILMS FROM SURFACES

#79
20230330196
2023-10-19

IMMUNOSUPPRESSIVE AGENTS

#80
20230330149
2023-10-19

ENHANCEMENT OF CARTILAGE REGENERATIVE ACTIVITY OF STEM CELL POPULATIONS BASED ON REDUCTION OF INTRA-ARTICULAR CELLULAR MATERIAL

#81
20230295597
2023-09-21

A DISINTEGRIN AND METALLOPROTEINASE WITH A THROMBOSPONDIN TYPE I MOTIF, MEMBER 13 (ADAMTS-13) MUTANTS, COMPOSITIONS AND THERAPEUTIC METHODS THEREOF

#82
20230277633
2023-09-07

PHARMACEUTICAL COMPOSITION OF ENZYMES AND VIRUSES AND APPLICATION THEREOF

#83
20230203469
2023-06-29

ADAMTS13 VARIANT, COMPOSITIONS, AND USES THEREOF

#84
20230203468
2023-06-29

Methods and compositions for inhibiting ADAM10 biological activities

#85
20230201319
2023-06-29

ADAMTS13 COMPOSITIONS AND METHODS FOR TREATING AND DIAGNOSING COMPLICATIONS OF CORONAVIRUS DISEASE

#86
20230201229
2023-06-29

Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces

#87
20230190758
2023-06-22

Methods of treating cancer using neuronal activity inhibiting agents

#88
20230183670
2023-06-15

RNAS FOR WOUND HEALING

#89
20230168251
2023-06-01

DIAGNOSTIC AGENT AND MEDICINE COMPRISING ADAMTS13 AS MAIN INGREDIENT

#90
20230158127
2023-05-25

COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES

#91
20230158126
2023-05-25

RNA FOR TREATMENT OR PROPHYLAXIS OF A LIVER DISEASE

#92
20230158125
2023-05-25

Pulmonary Administration of ACE2 Polypeptides

#93
20230143097
2023-05-11

Compositions And Methods To Reduce And/Or Dissolve Calcium Deposits In Arterial Walls

#94
20230130866
2023-04-27

Stabilized liquid and lyophilized ADAMTS13 formulations

#95
20230118328
2023-04-20

Enhanced delivery of antioxidants for treatment of central nervous system disorders involving oxidative stress

#96
20230056857
2023-02-23

Nanosystems for controlled transport of active molecules for diagnostic, prognostic and therapeutic purposes

#97
20230055292
2023-02-23

Dissolvable gel-forming film for delivery of active agents

#98
20230031268
2023-02-02

Stable thermolysin hydrogel

#99
20230027709
2023-01-26

COMPOSITIONS AND METHODS FOR REGULATING SAS1R

#100
20230000925
2023-01-05

METHOD OF USING ALLOGENEIC HAPLOIDENTICAL ADIPOSE TISSUE-DERIVED STROMAL VASCULAR FRACTION IN THE TREATMENT OF HUTCHINSON-GILFORD PROGERIA SYNDROME PATIENT

#101
20220378884
2022-12-01

CHIMERIC PROTEINS FOR SELECTIVE LYSIS OF BACTERIA

#102
20220364070
2022-11-17

ENDOTOXIN-REDUCED THERMOLYSIN

#103
20220362327
2022-11-17

COMPOSITIONS AND METHODS FOR WOUND HEALING

#104
20220348960
2022-11-03

VIRAL MEDIATED GENE DELIVERY FOR TRANSIENT EXPRESSION OF PROTEINS

#105
20220347274
2022-11-03

Compositions for remodeling extracellular matrix and methods of use thereof

#106
20220347273
2022-11-03

WOUND DEBRIDEMENT SYSTEMS

#107
20220339266
2022-10-27

ADAMTS13 TREATMENT TO ENHANCE GRAFT SURVIVAL

#108
20220323555
2022-10-13

Collagenase Clostridium for Treating Esophageal Ailments

#109
20220305094
2022-09-29

COLLAGENASE FORMULATIONS AND METHODS OF PRODUCING THE SAME

#110
20220249628
2022-08-11

USE OF RECOMBINANT ADAMTS13 FOR TREATING SICKLE CELL DISEASE

#111
20220249400
2022-08-11

SOLUBILIZATE WITH CURCUMIN AND BOSWELLIA AND XANTHOHUMOL

#112
20220249348
2022-08-11

METHODS FOR TREATING CELLULITE

#113
20220233606
2022-07-28

AN AMNIOTIC FLUID COMPOSITION AND METHOD OF USING

#114
20220168472
2022-06-02

ENZYME-DEGRADABLE HYDROGEL FOR DELIVERY OF A PAYLOAD

#115
20220133682
2022-05-05

SOLUBILIZATE WITH CURCUMIN AND AT LEAST THE CANNABINOID THC AS A FURTHER ACTIVE SUBSTANCE

#116
20220133646
2022-05-05

SOLUBILIZATE WITH CURCUMIN AND AT LEAST ONE CANNABINOID AS A FURTHER ACTIVE SUBSTANCE

#117
20220125741
2022-04-28

Solubilizate with curcumin and optionally at least one other active substance

#118
20220111017
2022-04-14

IMMUNOMODULATORY COMPOSITIONS AND METHODS

#119
20220080032
2022-03-17

Subcutaneous administration of ADAMTS13

#120
20220056088
2022-02-24

PEPTIDE DIRECTED PROTEIN KNOCKDOWN

#121
20220047689
2022-02-17

Collagenase for treatment of bladder dysfunction

#122
20220047688
2022-02-17

Use of ADAMTS13 for treating, ameliorating and/or preventing vaso-occlusive crisis in sickle cell disease, acute lung injury and/or acute respiratory distress syndrome

#123
20220047687
2022-02-17

CHEMICAL SCALPEL

#124
20220023399
2022-01-27

BLOOD COMPONENT POTENTIATION OF LYTIC PROTEIN ANTI-BACTERIAL ACTIVITY AND METHODS AND USES THEREOF

#125
20220002703
2022-01-06

ADAMTS13-CONTAINING COMPOSITIONS HAVING THROMBOLYTIC ACTIVITY

#126
20220001077
2022-01-06

Liquid Crystalline Collagen Materials and Use in Connective Tissue Repair

#127
20210395713
2021-12-23

Deimmunized lysostaphin and methods of use

#128
20210393501
2021-12-23

PREPARATION METHOD AND APPLICATION OF RECOMBINANT MUTANT COLLAGENASE

#129
20210386644
2021-12-16

Method of assessing and treating cellulite

#130
20210361767
2021-11-25

RESCUING CANCER PATIENTS FROM RESISTANCE TO TREATMENT WITH INHIBITORS OF PD-1/PD-L1 INTERACTIONS

#131
20210361671
2021-11-25

COMBINATION THERAPY CONTAINING IMMUNE BOOSTERS, DIGESTIVE ENZYMES AND INTERFERONS FOR CANCER TREATMENT

#132
20210353724
2021-11-18

PEGYLATED TETANUS NEUROTOXINS AND TREATMENT OF HYPOTONIA

#133
20210353723
2021-11-18

Methods, apparatuses and systems for adolescent idiopathic scoliosis treatment

#134
20210330764
2021-10-28

Collagenase Clostridium Histolyticum injection therapies

#135
20210322462
2021-10-21

WOUND PREVENTION AND/OR TREATMENT AND RELATED COMPOUNDS, MATRICES, COMPOSITIONS, METHODS AND SYSTEMS

#136
20210294124
2021-09-23

CONTACT LENS USE IN THE TREATMENT OF AN OPHTHALMOLOGIC CONDITION

#137
20210290687
2021-09-23

METHOD OF USING ALLOGENEIC HAPLOIDENTICAL ADIPOSE TISSUE-DERIVED STROMAL VASCULAR FRACTION IN THE TREATMENT OF HUTCHINSON-GILFORD PROGERIA SYNDROME PATIENT

#138
20210244642
2021-08-12

CELLULITE ERADICATION METHODS

#139
20210220284
2021-07-22

Treatment method and product for uterine fibroids using purified collagenase

#140
20210205422
2021-07-08

Suppression of bone cancer-induced allodynia

#141
20210187084
2021-06-24

INJECTION TECHNIQUES FOR THE TREATMENT OF CELLULITE

#142
20210162025
2021-06-03

VARIANTS OF TACE PRO-DOMAIN AS TNF-A INHIBITOR AND THEIR MEDICAL USE

#143
20210162017
2021-06-03

Directed stem cell recruitment

#144
20210128701
2021-05-06

COMPOSITIONS COMPRISING ADAMTS13 FOR USE IN METHODS FOR THE RECANALIZATION OF OCCLUDED BLOOD VESSELS IN AN INFARCTION

#145
20210113670
2021-04-22

Treatment of uterine fibroids using purified collagenase

#146
20210106659
2021-04-15

COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES

#147
20210085663
2021-03-25

COMPOSITIONS AND METHODS FOR TREATING CANCER WITH ATYPICAL BRAF MUTATIONS

#148
20210077538
2021-03-18

Methods and compositions for treatment of penile defects

#149
20210060143
2021-03-04

THERMOSENSITIVE HYDROGEL COLLAGENASE FORMULATIONS

#150
20210059936
2021-03-04

Collagenase loaded liposomes for enhancing drug delivery

#151
20210040468
2021-02-11

COMPOSITIONS AND METHODS FOR PRODUCING CLOSTRIDIAL COLLAGENASES

#152
20210023014
2021-01-28

Treatment Method and Product for Uterine Fibroids using Purified Collagenase

#153
20210015907
2021-01-21

Compositions for remodeling extracellular matrix and methods of use thereof

#154
20210010082
2021-01-14

Methods of Novel Therapeutic Candidate Identification Through Gene Expression Analysis in Vascular-Related Diseases

#155
20200397873
2020-12-24

COMPOSITIONS, SYSTEMS, AND METHODS FOR SCAR TISSUE MODIFICATION

#156
20200390870
2020-12-17

HUMANIZED ANTI-MUC1* ANTIBODIES AND DIRECT USE OF CLEAVAGE ENZYME

#157
20200390848
2020-12-17

Methods of treating wounds using cathepsin K inhibitors

#158
20200385485
2020-12-10

PROLIFERATION OF MUC1 EXPRESSING CELLS

#159
20200376098
2020-12-03

Stabilized liquid and lyophilized ADAMTS13 formulations

#160
20200362327
2020-11-19

ENDOTOXIN-REDUCED THERMOLYSIN

#161
20200354707
2020-11-12

Process for the production and purification of the collagenase enzyme from

#162
20200284793
2020-09-10

Diagnostic agent and medicine comprising ADAMTS13 as main ingredient

#163
20200277251
2020-09-03

NOVEL ANTIBACTERIAL COMPOUNDS AND METHODS OF MAKING AND USING SAME

#164
20200261623
2020-08-20

Biodegradable biomimetics of growth plate cartilage for the treatment of physeal injuries

#165
20200254073
2020-08-13

Enhanced delivery of antioxidants for treatment of central nervous system disorders involving oxidative stress

#166
20200254064
2020-08-13

Thermostable Composition Having Antiviral and Antibacterial Activity and the Use Thereof

#167
20200222346
2020-07-16

Solubilizate with curcumin and boswellia and xanthohumol

#168
20200206326
2020-07-02

Nucleic acid molecules encoding clostridium histolyticum collagenase I and methods of producing the same

#169
20200179490
2020-06-11

Collagen-mimetic peptide mediated delivery of nucleic acid carriers for efficient delivery from collagen

#170
20200164050
2020-05-28

Pharmaceutical composition containing botulinum neurotoxin

#171
20200155643
2020-05-21

Engineered anthrax protective antigen proteins for cancer therapy

#172
20200149026
2020-05-14

RNAs for wound healing

#173
20200140843
2020-05-07

METHOD FOR MONOMERIZING MATRIX METALLOPROTEINASE 7 (MMP-7) AGGREGATE

#174
20200129656
2020-04-30

ENZYMATIC WOUND DEBRIDING COMPOSITIONS WITH ENHANCED ENZYMATIC ACTIVITY

#175
20200129561
2020-04-30

DELIVERY OF AUTOLOGOUS CELLS COMPRISING MATRIX METALLOPROTEINASE FOR TREATMENT OF SCLERODERMA

#176
20200129452
2020-04-30

Solubilizate with curcumin and optionally at least one other active substance

#177
20200101144
2020-04-02

Subcutaneous administration of ADAMTS13

#178
20200078310
2020-03-12

Treatment Method and Product for Uterine Fibroids using Purified Collagenase

#179
20200040321
2020-02-06

Deimmunized lysostaphin and methods of use

#180
20200000891
2020-01-02

Composition, containing RGD motif-containing peptide or fragment thereof, for treating burns and glaucoma, alleviating skin wrinkles, and promoting hair growth

#181
20190382745
2019-12-19

Methods and compositions for inhibiting ADAM 9 biological activities

#182
20190381151
2019-12-19

Chimeric polypeptides and their use in bacterial decolonization

#183
20190369415
2019-12-05

Contact lens use in the treatment of an ophthalmologic condition

#184
20190365791
2019-12-05

Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces

#185
20190358305
2019-11-28

AAV-BASED GENE THERAPY FOR GLAUCOMA

#186
20190345473
2019-11-14

METHODS AND COMPOSITIONS FOR INHIBITING ADAM10 BIOLOGICAL ACTIVITIES

#187
20190343963
2019-11-14

CONJUGATED PROTEASE TARGETING MOIETIES

#188
20190343934
2019-11-14

Variants of TACE pro-domain as TNF-A inhibitor and their medical use

#189
20190343933
2019-11-14

RNA for treatment or prophylaxis of a liver disease

#190
20190343902
2019-11-14

Treatment and Prophylaxis for Neurological Conditions and Diseases

#191
20190338010
2019-11-07

Fusion proteins of collagen-binding domain and parathyroid hormone

#192
20190336588
2019-11-07

Use of ADAMTS13 for treating, ameliorating and/or preventing vaso-occlusive crisis in sickle cell disease, acute lung injury and/or acute respiratory distress syndrome

#193
20190315849
2019-10-17

Method of reducing the effect of a stroke comprising administering an inhibitor of vascular endothelial growth factor B (VEGF-B)

#194
20190315819
2019-10-17

Peptide directed protein knockdown

#195
20190307858
2019-10-10

Vasoconstrictive and antibacterial combination treatment for rosacea

#196
20190282677
2019-09-19

METHOD OF PREVENTING OR REDUCING BIOFILM FORMATION

#197
20190270825
2019-09-05

Methods and compositions for reducing cardiac damage and other conditions

#198
20190262437
2019-08-29

Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces

#199
20190247475
2019-08-15

Stabilized liquid and lyophilized ADAMTS13 formulations

#200
20190224287
2019-07-25

Implantable matrix having optimum ligand concentrations

#201
20190224239
2019-07-25

HEAT-EXPOSED PLATELET LYSATE COMPOSITIONS, AND METHODS FOR PREPARING AND USING SAME

#202
20190216722
2019-07-18

METHODS TO TREAT HEART FAILURE

#203
20190209666
2019-07-11

Flexible tissue matrix and methods for joint repair

#204
20190183986
2019-06-20

CELL MEMBRANE TRANSLOCATION OF REGULATED SNARE INHIBITORS, COMPOSITIONS THEREFOR, AND METHODS FOR TREATMENT OF DISEASE

#205
20190161746
2019-05-30

ADAMTS13-containing compositions having thrombolytic activity

#206
20190151423
2019-05-23

Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof

#207
20190144825
2019-05-16

Methods of treating cancer using cell based therapies

#208
20190142965
2019-05-16

Hydrogel for engineered immune response to D-chirality peptides

#209
20190135890
2019-05-09

Fusion proteins of collagen-binding domain and parathyroid hormone

#210
20190133620
2019-05-09

A device for ultrasonic-accelerated hematoma lysis or thrombolysis of intracerebral or intraventricular hemorrhages or hematomas

#211
20190117746
2019-04-25

COMPOSITIONS, SYSTEMS, AND METHODS FOR SCAR TISSUE MODIFICATION

#212
20190083435
2019-03-21

Oral microbiota promotion for immune system associated inflammations

#213
20190076678
2019-03-14

DERMATOLOGICAL COMPOSITION AUGMENTING PARACRINE SIGNALLING

#214
20190070272
2019-03-07

ENZYME-ACTIVATED COLLAGEN AND TISSUE MATRICES

#215
20190070215
2019-03-07

DEVICES AND METHODS FOR REDUCING THE APPEARANCE OF CELLULITE

#216
20190060509
2019-02-28

Enzymatic wound debriding compositions with enhanced enzymatic activity

#217
20190054157
2019-02-21

COMPOSITION AND METHOD OF PREPARATION OF PROTEASE MICROPARTICULATE SLOW RELEASE PREPARATION

#218
20190053995
2019-02-21

Methods for Treating Cellulite

#219
20190031771
2019-01-31

Human monoclonal autoantibodies to ADAMTS13 and uses thereof

#220
20190025293
2019-01-24

Reagents and methods for detecting PNH type II white blood cells and their identification as risk factors for thrombotic disorders

#221
20180369289
2018-12-27

CELL TRANSPLANTATION DEVICE

#222
20180360990
2018-12-20

Nanosystems for controlled transport of active molecules for diagnostic, prognostic and therapeutic purposes

#223
20180353577
2018-12-13

Cell therapy for the treatment of neurodegeneration

#224
20180339025
2018-11-29

ENZYME COMPOSITION FOR MANAGEMENT OF METABOLIC HEALTH

#225
20180339013
2018-11-29

Collagenase-derived peptides promote tissue regeneration and wound healing

#226
20180333471
2018-11-22

Chimeric polypeptides and their use in bacterial decolonization

#227
20180326024
2018-11-15

MATERIALS AND METHODS FOR TREATING EMBOLISM

#228
20180318402
2018-11-08

COMPOSITIONS AND METHODS COMPRISING SERRATIA PEPTIDASE FOR INHIBITION AND TREATMENT OF BIOFILMS RELATED TO CERTAIN CONDITIONS

#229
20180298366
2018-10-18

Cationic neurotoxins

#230
20180264037
2018-09-20

Functionalized tissue matrices

#231
20180250217
2018-09-06

Method of assessing and treating cellulite

#232
20180243338
2018-08-30

Medicine for treatment and/or prevention of ischemic diseases, method for improving angiogenesis-promoting activity of cells, or method for producing medicine

#233
20180237513
2018-08-23

Method of treating stroke by administering a compound that inhibits VEGF-B signaling in combination with a thrombolytic agent

#234
20180214511
2018-08-02

Engineered anthrax protective antigen proteins for cancer therapy

#235
20180207245
2018-07-26

Stabilized liquid and lyophilized ADAMTS13 formulations

#236
20180193387
2018-07-12

Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition

#237
20180187144
2018-07-05

Animal product-free culture medium for bacteria of the genus and a process for producing supernatant comprising one or more collagenolytic and gelatinolytic proteases

#238
20180169158
2018-06-21

Treatment for gastroesophageal reflux disease caused by a neurological disorder

#239
20180147265
2018-05-31

METHODS RELATING TO THE TREATMENT OF COLITIS AND INFLAMMATORY BOWEL DISEASE

#240
20180140684
2018-05-24

MODULATION OF MUSCLE AND ADIPOCYTE DISTRIBUTION AND FATE

#241
20180140678
2018-05-24

Directed stem cell recruitment

#242
20180133293
2018-05-17

Compositions for remodeling extracellular matrix and methods of use thereof

#243
20180125950
2018-05-10

LIVER CIRRHOSIS TREATMENT

#244
20180119143
2018-05-03

Therapeutic methods, products and compositions inhibiting ZNF555

#245
20180117127
2018-05-03

ENZYME COMPOSITION FOR THERAPEUTIC MANAGEMENT OF MUSCLE SORENESS

#246
20180110842
2018-04-26

COMPOSITIONS COMPRISING ADAMTS13 FOR USE IN METHODS FOR THE RECANALIZATION OF OCCLUDED BLOOD VESSELS IN AN INFARCTION

#247
20180092939
2018-04-05

Use of alginate oligomers in combating biofilms

#248
20180066052
2018-03-08

COMPOSITIONS AND METHODS FOR REGULATING SAS1R

#249
20180055918
2018-03-01

Clostridium histolyticum enzymes and methods for the use thereof

#250
20180042999
2018-02-15

Multimodal antimicrobial therapy

#251
20170369888
2017-12-28

ADAM12 inhibitors and their use against inflammation-induced fibrosis

#252
20170369546
2017-12-28

BMP peptides and methods of use

#253
20170368154
2017-12-28

Antimicrobial composition comprising pyrogenic silica and serrathiopeptidase and uses thereof

#254
20170368153
2017-12-28

Composition, containing RGD motif-containing peptide or fragment thereof, for treating burns and glaucoma, alleviating skin wrinkles, and promoting hair growth

#255
20170360986
2017-12-21

Collagenous tissue repair device

#256
20170360904
2017-12-21

Use of protease mixture in promoting wound healing

#257
20170355961
2017-12-14

METHOD OF ISOLATING CELLS FROM A TISSUE IN A MAMMAL

#258
20170354594
2017-12-14

PROTEASE COMPOSITIONS FOR USE IN MODIFYING SEMEN

#259
20170348226
2017-12-07

Pharmaceutical composition comprising botulinum, a non ionic surfactant, sodium chloride and sucrose

#260
20170333536
2017-11-23

Composition and method of preparation of protease microparticulate slow release preparation

#261
20170333356
2017-11-23

Treatment Method and Product for Uterine Fibroids using Purified Collagenase

#262
20170326211
2017-11-16

Cell therapy for the treatment of neurodegeneration

#263
20170326182
2017-11-16

Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition

#264
20170319590
2017-11-09

Pharmaceutical formulations of xanthine or xanthine derivatives, and their use

#265
20170314005
2017-11-02

Process for the production and purification of the collagenase enzyme from vibrio alginolyticus

#266
20170304413
2017-10-26

Implantable matrix having optimum ligand concentrations

#267
20170304412
2017-10-26

Variants of TACE pro-domain as TNF-A inhibitor and their medical use

#268
20170290863
2017-10-12

ENDOMETRIAL STEM CELLS AND METHODS OF MAKING AND USING SAME

#269
20170285013
2017-10-05

Reagents and methods for detecting PNH type II white blood cells and their identification as risk factors for thrombotic disorders

#270
20170266422
2017-09-21

Methods and systems for toxin delivery to the nasal cavity

#271
20170266267
2017-09-21

Treatment of ophthalmic conditions

#272
20170266123
2017-09-21

COATED PARTICLES FOR DRUG DELIVERY

#273
20170246216
2017-08-31

Human amniotic fluid preparation having long-term stability

#274
20170239302
2017-08-24

Treatment and prophylaxis for neurological conditions and diseases

#275
20170224785
2017-08-10

Subcutaneous administration of ADAMTS13

#276
20170209552
2017-07-27

Pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers

#277
20170209551
2017-07-27

Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof

#278
20170198060
2017-07-13

Fungal-specific metalloproteases and uses thereof

#279
20170189478
2017-07-06

Hatching fluid enzymes and uses thereof

#280
20170152524
2017-06-01

Gene therapy for neurometabolic disorders

#281
20170151316
2017-06-01

METHODS OF INCREASING MUSCLE MASS USING NON-TOXIC TETANUS TOXIN C FRAGMENT (TTC)

#282
20170145505
2017-05-25

Methods of Novel Therapeutic Candidate Identification Through Gene Expression Analysis in Vascular-Related Disease

#283
20170145398
2017-05-25

Deimmunized lysostaphin and methods of use

#284
20170112906
2017-04-27

Stabilized liquid and lyophilized ADAMTS13 formulations

#285
20170106058
2017-04-20

PHARMACEUTICAL COMPOSITION AGAINST CHRONIC BACTERIAL INFECTIONS

#286
20170101457
2017-04-13

Fusion proteins of collagen-binding domain and parathyroid hormone

#287
20170095542
2017-04-06

Reduction of Lipoma Tissue

#288
20170087229
2017-03-30

COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES

#289
20170081654
2017-03-23

Method for monomerizing matrix metalloproteinase 7 (MMP-7) aggregate

#290
20170072029
2017-03-16

Enzymatic wound debriding compositions with enhanced enzymatic activity

#291
20170065743
2017-03-09

Enzyme-activated collagen and tissue matrices

#292
20170065686
2017-03-09

Composition Exhibiting a von Willebrand Factor (vWF) Protease Activity Comprising a Polypeptide Chain with the Amino Acid Sequence AAGGILHLELLV

#293
20170049866
2017-02-23

Cell Membrane Translocation of Regulated Snare Inhibitors, Compositions Therefor, and Methods for Treatment of Disease

#294
20170028037
2017-02-02

Reduced-pressure treatment systems and methods employing debridement mechanisms

#295
20160375111
2016-12-29

Stabilized liquid and lyophilized ADAMTS13 formulations

#296
20160369256
2016-12-22

Cationic neurotoxins

#297
20160367647
2016-12-22

Treatment of ophthalmic conditions

#298
20160354450
2016-12-08

Method for Treating Adhesive Capsulitis

#299
20160346367
2016-12-01

Thermosensitive hydrogel collagenase formulations

#300
20160346247
2016-12-01

Gelatinase inhibitors and prodrugs