95260 ⎘
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Histone demethylase inhibitors
#2702Asymmetric ureas and medical uses thereof
#2703Urea derivative or pharmacologically acceptable salt thereof
#2704Kinase inhibitors
#2705Sulfonylureas and related compounds and use of same
#2706ALPHA-CINNAMIDE COMPOUNDS AND COMPOSITIONS AS HDAC8 INHIBITORS
#2707Lipids and compositions for the delivery of therapeutics
#2708Theramutein modulators
#2709Phenyl derivative
#2710Substituted Tricyclics and Method of Use
#2711Substituted pyrimidine compounds as phosphatidylinositol 3-kinase delta inhibitor and use thereof
#2712Therapeutic compounds and uses thereof
#2713Aminoquinazoline compounds as Aantagonist
#2714Inhibitors of tryptophan-2,3-dioxygenase or indoleamine-2,3-dioxygenase
#2715Compounds
#2716Substituted N-bicyclo-2-aryl-quinolin-4-carboxamides and use thereof
#2717Quinoline derivative for use in the treatment and prevention of viral infections
#2718Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders
#2719Polymorphic Forms of Afatinib Dimaleate
#2720Quinazolines as potassium ion channel inhibitors
#2721Substituted benzofuran compounds for the treatment of hepatitis C
#2722Benzofurans substituted with primary benzamide as HCV inhibitors
#2723Benzofuran compounds for the treatment of hepatitis C
#2724Bicyclic quinazolinone derivatives
#2725Compounds for inhibiting c-Myc/Max/DNA complex formation
#2726Pharmaceutically active compounds
#2727PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING
#2728S1P modulating agents
#2729Spirobifluorene derivative-based materials for electronic devices
#2730Development of ABCG2-Sensitive Fluorescent Probe For Isolation of ABCG2low Neural Stem/Progenitor Cells
#2731Liquid crystal compound having benzopyran skeleton, liquid crystal composition, and liquid crystal display device
#2732Compounds for treatment of complement mediated disorders
#2733Ether compounds for treatment of complement mediated disorders
#2734Compounds for the treatment of hepatitis C
#2735Compounds for stabilizing ryanodine receptors from aberrant levels of calcium release
#2736Polymerizable compound and optical isomer
#2737Process for the preparation of histamine H3 receptor modulators
#27384-heteroaryl substituted benzoic acid compounds as RORgammaT inhibitors and uses thereof
#2739GLP-1 receptor modulators
#2740Autotaxin inhibitors
#2741INHIBITORS OF HISTONE DEACETYLASE
#27425-hydroxytryptamine receptor 7 activity modulators and their method of use
#27435-hydroxytryptamine receptor 7 activity modulators and their method of use
#2744HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
#2745Methods of Treating an Overweight or Obese Subject
#2746HUMAN HELICASE DDX3 INHIBITORS AS THERAPEUTIC AGENTS
#2747Substituted pyrazole compounds as RORgammaT inhibitors and uses thereof
#2748Pyridic ketone derivatives, method of preparing same, and pharmaceutical application thereof
#2749Pyridone amides as modulators of sodium channels
#2750Herbicidal phenylpyridines
#2751Inhibitors of beta-hydroxylase for treatment of cancer
#2752Chromenone inhibitors of monocarboxylate transporters
#2753Crystalline form of a benzimidazole derivative and a preparation method thereof
#2754Protein tyrosine kinase modulators and methods of use
#2755Inhibitors of TrkA kinase
#2756Anthelmintic compounds, compositions and method of using thereof
#2757Therapeutic compounds and uses thereof
#2758Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
#27592-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof
#2760Compositions and methods for treating metabolic disorders
#2761Immunomodulator compounds
#2762T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
#2763Substituted mono- and polyazanaphthalene derivatives and their use
#2764USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES
#2765MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY
#2766Tricyclic spiro compound
#2767PARTIALLY SATURATED TRICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME
#2768PROCESS FOR PREPARING BENZOFURAN-2-CARBOXAMIDE DERIVATIVES
#2769S-TRIAZOLYL ALPHA-MERCAPTO ACETANILIDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE
#27705-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis
#2771Organic light emitting device
#2772Aryl sulfonamides
#2773Compounds, compositions, and methods for increasing CFTR activity
#2774Cyclic compounds substituted by a condensed ring system
#2775Modulation of Bacterial Quorum Sensing with Synthetic Ligands
#2776Kinase inhibitors for the treatment of disease
#2777INHIBITORS OF HISTONE DEMETHYLASES
#2778Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof
#2779Treatment or prophylaxis of proliferative conditions
#2780Piperazine-substituted benzothiophenes for treatment of mental disorders
#2781Antibacterial compounds
#2782Amine compound and organic light emitting element comprising same
#2783Conjugates for assays for oxycodone and oxymorphone
#2784Neprilysin inhibitors
#2785Small molecule inhibitors of fibrosis
#2786ANTI-ESTROGENIC COMPOUNDS
#2787PRO-SURVIVAL COMPOUNDS
#2788Pyrimidine FGFR4 inhibitors
#2789Use of EP4 receptor antagonists in the treatment of cartilage disease
#2790Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto
#2791N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests
#2792AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS
#2793Ethyldiamine orexin receptor antagonists
#2794Neprilysin inhibitors
#2795Substituted pyridyl-cycloalkyl-carboxylic acids, compositions containing them and medical uses thereof
#2796Compounds active towards bromodomains
#2797Biaryl derivative as GPR120 agonist
#2798Chemokine CXCR1 and CXCR2 receptor antagonist compounds, and use thereof in the treatment of chemokine-mediated pathologies
#2799Neprilysin inhibitors
#2800Hydroxyl compounds and compositions for cholesterol management and related uses
#2801ULK1 inhibitors and methods using same
#2802Triazolo[4,5-D] pyramidine derivatives and their use as purine receptor antagonists
#2803Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
#2804Blockers of the growth hormone receptor in disease prevention and treatment
#2805Indazole sulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (ROR γ (T))
#2806HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
#2807Fumagillol heterocyclic compounds and methods of making and using same
#2808COMPOUNDS AND METHODS OF USE THEREOF
#2809Fumigillol compounds and methods of making and using same
#2810Pegylated carfilzomib compounds
#2811Macrocyclic picolinamides as fungicides
#2812Compounds and methods for activating the apoptotic arm of the unfolded protein response
#2813Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof
#2814Mixed disulfide conjugates of thienopyridine compounds and uses thereof
#2815Quinazoline derivatives substituted by aniline, preparation method and use thereof
#2816Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
#2817CXCR7 receptor modulators
#2818Opioid receptor ligands and methods of using and making same
#2819Imaging composition and uses thereof
#2820Heterocyclic compounds for use in electronic devices
#2821Neprilysin inhibitors
#2822CARM1 inhibitors and uses thereof
#2823HIV replication inhibiting pyrimidines
#2824Triazabutadienes as cleavable cross-linkers
#2825Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof
#2826Inhibitors of histone demethylases
#2827Compounds and their use as BACE inhibitors
#2828COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR
#2829ORGANIC ELECTRONIC DEVICE AND DISPLAY APPARATUS USING COMPOSITION FOR ORGANIC ELECTRONIC DEVICE
#2830GLP-1 receptor modulators
#2831EGFR inhibitor, preparation method and use thereof
#2832Therapeutic compounds and uses thereof
#2833Process of synthesizing 3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1] heptane-2-carboxylic acid
#2834Dual-warhead covalent inhibitors of FGFR-4
#2835METHODS OF TREATING CANCER
#2836METHODS OF TREATING CANCER
#2837Anti-endothelial lipase compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases
#2838Heterocyclic compounds as pesticides
#2839QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF
#2840Carbamate, ester, and ketone compounds for treatment of complement mediated disorders
#2841Amide compounds for treatment of complement mediated disorders
#2842Glycosidase inhibitors
#2843Tetrahydroisoquinoline derived PRMT5-inhibitors
#2844Compounds as rearranged during transfection (RET) inhibitors
#2845HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE
#2846Therapeutically active compounds and their methods of use
#28475-hydroxytryptamine receptor 7 activity modulators and their method of use
#2848Pyrimidines as sodium channel blockers
#2849Histone demethylase inhibitors
#2850Diamino-Pyridine, Pyrimidine, and Pyridazine Modulators of the Histamine H4 Receptor
#2851Pyrrolic amide compound and preparation method and application thereof
#2852Use of picolinamide compounds as fungicides
#2853Kinase inhibitors
#2854Substituted oxopyridine derivatives
#2855Small molecule regulators of steroid receptor coactivators and methods of use thereof
#2856Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules
#2857CARM1 INHIBITORS AND USES THEREOF
#2858Compounds for the treatment of paramyxovirus viral infections
#2859Tetrahydroisoquinoline derived PRMT5-inhibitors
#2860ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
#2861Crystalline forms of 6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethylbenzofuran-3-carboxamide
#2862Synthesis of isoflavanes and intermediates thereof
#2863PYRIMIDINEDIONE COMPOUNDS
#2864Benzenesulfonyl-asymmetric ureas and medical uses thereof
#2865Therapeutic compounds and uses thereof
#2866Specific inhibitors of methionyl-tRNA synthetase
#2867Isoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2
#2868Estrogen receptor modulators and uses thereof
#2869Hydantoin derivatives useful as Kv3 inhibitors
#2870Anesthetic compounds and related methods of use
#2871MACROCYCLIC PICOLINAMIDES AS FUNGICIDES
#2872MACROCYCLIC PICOLINAMIDES AS FUNGICIDES
#2873Piperazine derivatives for treating disorders
#2874Quinazolin-THF-amines as PDE1 inhibitors
#2875Process for preparing benzofuran-2-carboxamide derivatives
#2876Sodium channel blockers
#2877Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith
#2878Pyrazolyl guanidine FF-ATPase inhibitors and therapeutic uses thereof
#2879Arginine methyltransferase inhibitors and uses thereof
#2880Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C
#2881Biaryl amide compounds as kinase inhibitors
#2882Androgen receptor modulating compounds
#2883Compounds and compositions as kinase inhibitors
#2884Sulfoximine substituted quinazolines for pharmaceutical compositions
#2885Benzene, Pyridine, and Pyridazine Derivatives
#2886Compounds
#2887Heteroaryl compounds for kinase inhibition
#2888Heterocyclic compound
#2889SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS
#2890Kinase inhibitors
#2891Nampt Inhibitors
#2892Aryl-or heteroaryl-substituted benzene compounds
#2893Inhibitors of IRAK4 activity
#2894Methods and compositions for inhibition of Ras
#2895HETEROCYCLIC SULFONAMIDES, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF
#2896Pyridine derivatives as soft rock inhibitors
#2897PROCESSES FOR THE PREPARATION OF EMPAGLIFLOZIN
#2898Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof
#2899SUBSTITUTED PYRIMIDINES AS INHIBITORS OF HIF PROLYL HYDROXYLASE
#2900Substituted Pyrrolidine Carboxamide Compounds
#29012,4-pyrimidinediamine compounds and their uses
#2902Crystalline form of afatinib dimaleate
#2903Methods and compounds for restoring mutant p53 function
#2904Benzofuran analogue as NS4B inhibitor
#2905Pyrimidine derivatives for the treatment of viral infections
#2906Fused tricyclic urea compounds as raf kinase and/or raf kinase dimer inhibitors
#2907Heterocyclic compounds as NaV channel inhibitors and uses thereof
#2908Cyclooctenes for bioorthogonol reactions
#2909HSP70 modulators and methods for making and using the same
#2910SUBSTITUTED QUINOLINE-4-CARBOXAMIDES AND USE THEREOF
#2911Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof
#2912IDO inhibitors
#2913PPAR agonists and methods of use thereof
#2914Substituted piperidine compound and use thereof
#2915Inhibitors of PI3K-delta and methods of their use and manufacture
#2916PHTHALAZINONE DERIVATIVES
#2917Selective inhibitors of constitutive androstane receptor
#2918Quinazoline derivative
#2919Benzamide derivatives as modulators of the follicle stimulating hormone
#2920Cyanoquinoline derivatives
#2921Pyrrolidinone derivatives as MetAP-2 inhibitors
#2922Potent dual BRD4-kinase inhibitors as cancer therapeutics
#2923TLR-independent small molecule adjuvants
#2924Ligand-directed covalent modification of protein
#2925Inhibitors of IRAK4 activity
#2926Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders
#2927Pyrimidine-2,4-diamine derivatives for treatment of cancer
#29284-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group
#2929Crystalline forms of vilazodone hydrochloride and vilazodone free base
#2930Bicyclic arylcarboxylic acid amides and their use as herbicides
#2931Aminopyrimidine derivatives for use as modulators of kinase activity
#2932EZH2 inhibitors for treating lymphoma
#2933Methods for treating depressive symptoms
#2934Compositions and methods for targeting receptors expressed in the gut
#2935Organic optoelectronic device and display device
#2936COMPOUND HAVING A DIFLUOROCYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
#2937Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
#2938THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE
#2939Heteroaryl substituted pyridyl compounds useful as kinase modulators
#2940ERK inhibitors and uses thereof
#2941Pyrimidine carboxamides as sodium channel blockers
#29423-aryl propiolonitrile compounds for thiol labeling
#2943Apigenin analogs, compositions, and methods related thereto
#2944Heterocyclic compounds having cholesterol 24-hydroxylase activity
#2945Inhibitors of bacterial DNA gyrase with efficacy against gram-negative bacteria
#2946Heteroaryl substituted compounds as RORγ inhibitors
#2947MTH1 inhibitors for treatment of cancer
#2948Immunoregulatory agents
#29493-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives
#2950Heteroaryl compounds for kinase inhibition
#2951Benzimidazol-2-amines as MIDH1 inhibitors
#29523-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives
#2953Pyridine derivative
#2954Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease
#2955Pyrazole compounds and methods of making and using same
#2956Amino compounds for treatment of complement mediated disorders
#2957Neprilysin inhibitors
#2958Compound and organic light-emitting device including the same
#2959MACROCYCLIC PICOLINAMIDES COMPOUNDS WITH FUNGICIDAL ACTIVITY
#2960Carbazole-based compound and organic light-emitting device including the same
#2961Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists
#2962Tank-binding kinase inhibitor compounds
#2963Substituted indole Mcl-1 inhibitors
#2964HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
#2965POCHOXIME CONJUGATES USEFUL FOR THE TREATMENT OF HSP90 RELATED PATHOLOGIES
#2966Sulfoximine substituted quinazolines for pharmaceutical compositions
#2967Inhibitors of the fibroblast growth factor receptor
#29683-substituted carbonyl-naphtho[2,3-B]furane derivative or pharmaceutically acceptable salt thereof
#2969Antidiabetic substituted heteroaryl compounds
#2970Apelin receptor (APJ) agonists and uses thereof
#29712-amino-benzimidazole derivatives and their use as 5-lipoxygenase and/or prostaglandin E synthase inhibitors
#2972O-GLCNAC TRANSFERASE (OGT) INHIBITORS AND USES THEREOF
#2973FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS
#2974Beta-arrestin-biased cannabinoid CB1 receptor agonists and methods for making and using them
#2975Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals
#2976Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
#2977N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
#2978Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
#2979Compositions and methods of modulating 15-PGDH activity
#2980Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
#2981Aromatic amine derivatives and organic electroluminescent elements using same
#2982Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods
#2983Low-molecular-compound for improving production, maintenance and proliferation of pluripotent stem cells, composition comprising the same, and culture method
#2984Hamamelitannin analogues and uses thereof
#2985Bromodomain inhibitors
#2986Pyrimidinone derivative having autotaxin-inhibitory activity
#2987MULTIVALENT RAS BINDING COMPOUNDS
#2988Compounds and methods for inhibiting fascin
#2989Histone demethylase inhibitors
#2990Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient
#2991Histone demethylase inhibitors
#2992Substituted indazole derivatives active as kinase inhibitors
#2993Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
#29942-amino-5-keto-pyrimidine derivatives and the use thereof for controlling undesired plant growth
#2995FUNCTIONALISED AND SUBSTITUTED CARBAZOLES AS ANTI-CANCER AGENTS
#2996CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
#2997Anti-depression compounds
#2998TRPV1 vanilloid receptor antagonists with a bicyclic portion
#2999Benzimidazole derivatives as kinase inhibitors
#3000Compositions and methods for quadricyclane modification of biomolecules