95321 ⎘
Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
Sub-classes:Diamine Derivatives as Inhibitors of Leukotriene A4 Hydrolase
#2NLRP3 INFLAMMASOME INHIBITORS
#3EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF
#4Soluble Epoxide Hydrolase Inhibitors and Use Thereof
#5POLYCYCLIC COMPOUND AND APPLICATION THEREOF
#6SUBSTITUTED CYCLIC MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME
#7Pyrimidine compound as JAK kinase inhibitor
#8SMALL MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF ALS AND RELATED DISORDERS
#9COMPOSITIONS FOR MODULATING SPLICING
#101H-BENZO[D]IMIDAZOLE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS
#11Diamine derivatives as inhibitors of leukotriene Ahydrolase
#12QUINAZOLINE COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF
#13CHEMICAL COMPOUNDS
#14PRMT5 INHIBITORS
#15SMYD Inhibitors
#16Antimicrobial Compounds and Methods
#17Serotonin 5-HT2B inhibitory compounds
#18Methods and compositions for modulating splicing
#19HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF
#20METHODS AND COMPOSITIONS FOR MODULATING SPLICING
#21Pyrimidine compound as JAK kinase inhibitor
#22NLRP3 inflammasome inhibitors
#23ADO-resistant cysteamine analogs and uses thereof
#24Bicyclic aza compounds as muscarinic Mand/or Mreceptor agonists
#25MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN
#26Compounds for the treatment of cancer
#27Hepatitis B antiviral agents
#28Pyrimidine compound as JAK kinase inhibitor
#29SMYD INHIBITORS
#30HISTONE DEACETYLASE INHIBITORS
#31Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
#32Pyrimidine compound as JAK kinase inhibitor
#33NLRP3 inflammasome inhibitors
#34NLRP3 inflammasome inhibitors
#35Diamine derivatives as inhibitors of leukotriene A4 hydrolase
#36Chemical compounds
#37Methods and compositions for modulating splicing
#38Methods and compositions for modulating splicing
#39Methods and compositions for modulating splicing
#40Hepatitis B antiviral agents
#41Pyrimidine compound as JAK kinase inhibitor
#42Pyrimidine compounds as JAK kinase inhibitors
#43Histone deacetylase inhibitors
#44Benzopiperazine compositions as BET bromodomain inhibitors
#45CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE
#46SMYD INHIBITORS
#47HETEROAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES
#48Thionyl tetrafluoride modified compounds and uses
#49Pyrimidine compound as JAK kinase inhibitor
#50Triazolopyridines
#516-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof
#52Therapeutic compound for pain and synthesis thereof
#53Hepatitis B antiviral agents
#54Histone deacetylase inhibitors
#55Biphenyl compound or salt thereof
#56SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS
#57(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
#58Therapeutic compounds for pain and synthesis thereof
#59Therapeutic compounds for pain and synthesis thereof
#60Inhibitors of cyclin-dependent kinase 7 (CDK7)
#61Benzopiperazine compositions as BET bromodomain inhibitors
#62Nitrogen-containing aromatic heterocyclic compound
#63Pyrimidine compounds as JAK kinase inhibitors
#64Therapeutic compounds for pain and synthesis thereof
#65AMINE DERIVATIVES AS POTASSIUM CHANNEL BLOCKERS
#66Bicyclic aza compounds as muscarinic M1 receptor antagonists
#67Selective alpha-7 nicotinic receptor agonists and methods for making and using them
#68DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE
#69Substituted pyrazoles as IRAK inhibitors
#70Therapeutic compounds and uses thereof
#71Selectively substituted quinoline compounds
#72Heteroaryl compounds as IRAK inhibitors and uses thereof
#73Substituted piperidine compounds
#74Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer
#75Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
#76Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
#77Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
#78Hepatitis B antiviral agents
#79Bicyclic AZA compounds as muscarinic M1 receptor antagonists
#80Heterocyclic compounds having cholesterol 24-hydroxylase activity
#81Inhibitors of cyclin-dependent kinase 7 (CDK7)
#82Amine derivatives as potassium channel blockers
#831-(3-aminopropyl) substituted cyclic amine compounds, preparation method therefor, and pharmaceutical compositions and uses thereof
#84(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
#85ADO-resistant cysteamine analogs and uses thereof
#86Metallo-beta-lactamase inhibitors
#87SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS
#88SUBSTITUTED PHENYLALANINE DERIVATIVES
#89HETEROMAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLFERATIVE DISEASES
#903,3-disubstituted-(8-aza-bicyclo[3.2.1]OCT-8-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanones as inhibitors of 11 (β)-HSD1
#91Substituted pyrimidine compounds, compositions and medicinal applications thereof
#92Substituted-quinoxaline-type piperidine compounds and the uses thereof
#93Heteroaryl compounds as IRAK inhibitors and uses thereof
#94Bicyclic aza compounds as muscarinic M1 receptor agonists
#95Heterocyclic compounds having cholesterol 24-hydroxylase activity
#96Autotaxin inhibitors
#97Amine Derivatives as Potassium Channel Blockers
#98Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
#99Inhibitors of DNA gyrase for the treatment of bacterial infections
#100Fluorine substituted cyclic amine compounds and preparation methods, pharmaceutical compositions, and uses thereof
#101Quinoline derivatives as bromodomain inhibitors
#102Substituted-quinoxaline-type piperidine compounds and the uses thereof
#103Diamine derivatives as inhibitors of leukotriene A4 hydrolase
#104PHTHALAZINE DERIVATIVES AS PARP INHIBITORS
#105Oxazole tyrosine kinase inhibitors
#106(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
#107Amine derivatives as potassium channel blockers
#108Polycyclic heteroaryl substituted triazoles useful as axl inhibitors
#109Heterocyclic derivative having PGD2 receptor antagonist activity
#110Compounds and compositions for the inhibition of NAMPT
#111Crystalline form of a quinolinone-carboxamide compound
#112CCR5 antagonists for treating HIV
#113Tetrahydroquinoline analogues as muscarinic agonists
#114Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
#115Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators
#116Autotaxin inhibitors
#117Quinolinone-carboxamide compounds as 5-HTreceptor agonists
#118Nitrogen-containing aromatic heterocyclic compound
#119Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators
#120Chemically Programmed Vaccination
#121Rock inhibitors
#1221,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof
#123MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
#124Bridged bicyclic RHO kinase inhibitor compounds, compositions and use
#125Modulators of Muscarinic Receptors
#126Derivatives of pyrazolophenyl-benzenesulfonamide compounds and use thereof as antitumor agents
#127Crystalline forms of maraviroc phosphate and process for maraviroc amorphous form
#128Bicyclic amides for enhancing glutamatergic synaptic responses
#129Substituted pyrazines and their use in the treatment of disease
#1303,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanones as inhibitors of 11 (β)-HSD1
#131DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE
#132Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of the chemotaxis of polymorphonucleate and mononucleate cells
#133Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
#1344-substituted-2-phenoxy-phenylamine delta opioid receptor modulators
#135Therapeutic compounds
#136Spiroindoline modulators of muscarinic receptors
#137Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
#138Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors
#139Bridged piperidine derivatives
#140HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE
#141Chemically programmed vaccination
#142Nicotinamide Derivatives
#143DIAMINOPYRIMIDINECARBOXAMIDE DERIVATIVE
#144Aryl-substituted bridged or fused diamines as modulators of leukotriene Ahydrolase
#145Aryl-substituted bridged or fused diamines as modulators of leukotriene A ydrolase
#146Amide compounds, their pharmaceutical compositions, their preparation method and their uses
#147INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF
#148Dual NK1/NK3 receptor antagonists
#149Alkyl 3-((2-amidoethyl)amino)-8-azabicyclo[3.2.1]octane-8-carboxylate analogs as selective M1 agonists and methods of making and using same
#150HSP90 inhibitory carbazole derivatives, compositions containing same and use thereof
#151TRIAZOLYL TROPANE DERIVATIVES
#152Process, salts, composition and use
#153Bridged bicyclic RHO kinase inhibitor compounds, composition and use
#1545-PHENYL-4-METHYL-THIAZOL-2-YL-AMINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3 KINASE ENZYMES (PI3) FOR THE TREATMENT OF INFLAMMATORY DISEASES
#155Biaryl substituted azabicyclic alkane derivatives
#1565-PHENYL-4-METHYL-THIAZOL-2-YL-AMINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3 KINASE ENZYMES (PI3) FOR THE TREATMENT OF INFLAMMATORY DISEASES
#157PREPARATION AND UTILITY OF CCR5 INHIBITORS
#158COMPOUNDS
#159NOVEL 8-AZA-BICYCLO[3.2.1]OCTANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS
#160IL-8 RECEPTOR ANTAGONISTS
#161Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors
#162Phthalazine derivatives as PARP inhibitors
#163IL-8 RECEPTOR ANTAGONISTS
#164Substituted bicyclic piperidinyl- and piperazinyl-sulfonamides useful to inhibit 11β-hydroxysteroid dehydrogenase type-1
#165Pyrimidine compound
#166HETEROCYCLIC JANUS KINASE 3 INHIBITORS
#167Methods for the treatment of respiratory depression
#168TROPANE DERIVATIVES USEFUL AS PESTICIDES
#169BICYCLOAMINE DERIVATIVES
#170DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR
#171Quinolinone-carboxamide compounds as 5-HTreceptor agonists
#172Spiroindoline modulators of muscarinic receptors
#173Fused thiophene derivatives as kinase inhibitors
#174Oxazole tyrosine kinase inhibitors
#175Thiazole Amides, Imidazole Amides and Related Analogues
#176Indazole-carboxamide compounds
#177Bicyclic amides for enhancing glutamatergic synaptic responses
#178Quinolinone-carboxamide compounds as 5-HTreceptor agonists
#179Indazole-carboxamide compounds as 5-HTreceptor agonists
#180HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE
#1814-sulfonylpiperidine derivatives
#182Substituted-quinoxaline-type piperidine compounds and the uses thereof
#183Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity
#184Diamine derivatives as inhibitors of leukotriene A4 hydrolase
#185Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
#186Crystalline form of a quinolinone-carboxamide compound
#187Preparation of Retapamulin via its Pleuromutilin-thiol precursor
#1882,4-pyrimidinediamine compounds for treatment of inflammatory disorders
#189Muscarinic Receptor Agonists that are Effective in the Treatment of Pain, Alzheimer's Disease and Schizophrenia
#190Polycyclic heteroaryl substituted triazoles useful as axl inhibitors
#191Pyrimidine derivatives
#192CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS
#193Modulators of Muscarinic Receptors
#19411 β-HSD1 modulators
#195TRICYCLIC DELTA OPIOID MODULATORS
#196TROPINE MODULATORS OF 5-HT3 RECEPTOR
#197Polymorphic form of granisetron hydrochloride and methods of making the same
#198PIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR CCR5
#199IL-8 receptor antagonists
#200Diaminopyrimidinecarboxamide derivative
#201Aryl sulfonamides useful as inhibitors of chemokine receptor activity
#202Heterocyclic janus kinase 3 inhibitors
#203Bicycloamine derivatives
#204Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
#205Aminopiperidinyl derivatives and uses thereof
#20611 Beta-HSD1 Modulators
#207Tetrahydroquinoline analogues as muscarinic agonists
#208Phenyl-piperazine derivatives as modulators of muscarinic receptors
#209Amorphous retapamulin and processes for preparation thereof
#2102-aminopyridine kinase inhibitors
#211Biaryl substituted azabicyclic alkane derivatives
#212Indane compounds as CCR5 antagonists
#213Process for the preparation of Retapamulin and its intermediates
#214Dual NK1/NK3 receptor antagonists
#215PYRAZOLE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER AND AUTOIMMUNE DISORDERS
#216N-amide Derivatives of 8-Azabicyclo[3.2.1]OCT-3-YL AS CCR1 Antagonists
#217CHEMICAL COMPOUNDS
#218Nicotinic acetylcholine receptor modulators
#219Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
#220Aryl-substituted bridged or fused diamines as modulators of leukotriene Ahydrolase
#2213-monosubstituted tropane derivatives as nociceptin receptor ligands
#222IL-8 Receptor Antagonists
#223DEUTERIUM-ENRICHED RETAPAMULIN
#224DEUTERIUM-ENRICHED MARAVIROC
#225HETEROCYCLIC COMPOUNDS AS CCR5 ANTAGONISTS
#226Tricyclic δ-opioid modulators
#227Quinolinone compounds as 5-HTreceptor agonists
#228Heterocyclic compounds as inhibitors of 17beta-HSD3
#229Organic Compounds
#2305-phenyl-4-methyl-thiazol-2-yl-amine derivatives as inhibitors of phosphatidylin ositol 3 kinase enzymes (PI13) for treatment of inflammatory diseases
#231Benztropinamine Analogs as Dopamine Uptake Inhibitors
#2328-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
#233CXCR4 chemokine receptor binding compounds
#2345-HTreceptor agonist compounds
#2352-aminobenzoxazole carboxamides as 5HT3 modulators
#236Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors
#237Quinolinone-carboxamide compounds as 5-HT, receptor agonists
#238Novel Method
#239Quinolinone-carboxamide compounds
#240Polymorph of mutilin
#241Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity
#242Triazolyl tropane derivatives
#243Indazole-carboxamide compounds as 5-HTreceptor agonists
#244PREPARATION AND UTILITY OF CCR5 INHIBITORS
#245Phthalazine derivatives as parp inhibitors
#246Tropane derivatives useful in therapy
#247Indazole-carboxamide compounds
#248Benzoxazole carboxamides for treating CINV and IBS-D
#249Muscarinic modulators
#250Carbamate compounds as 5-HTreceptor agonists
#251Benzoimidazolone-carboxamide compounds as 5-HT4 receptor agonists
#252OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS
#253Modulators of muscarinic receptors
#254ANDROGEN RECEPTOR MODULATORS AND METHOD OF TREATING DISEASE USING THE SAME
#255Modulators of melanocortin receptor
#256Quinolinone-carboxamide compounds as 5-HTreceptor agonists
#257Quinolinone-carboxamide compounds as 5-HT, receptor agonists
#258Substituted bis aryl and heteroaryl compounds as selective 5HTantagonists
#259Arylphenylamino-,Arylphenylamide-, and Arylphenylether-Sulfide Derivatives
#260IL-8 receptor antagonists
#2613-monosubstituted tropane derivatives as nociceptin receptor ligands
#262BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF
#263Compounds As Ccri Antagonists
#264AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
#265Aminotropane derivatives, preparation thereof and therapeutic use thereof
#266Process for preparing intermediates to 5-HT receptor agonist compounds
#2672,6-disubstituted piperiddines as modulators
#268Piperidine derivatives as modulators of chemokine receptor CCR5
#269Diamine derivatives as inhibitors of leukotriene Ahydrolase
#270OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
#271E-fluoro-4-(pyridin-2-yl)-piperidine-1-carboxamide derivatives and related compounds which modulate the function of the vanilloid-1 receptor (vr1) for the treatment of pain
#272Carbamate compounds as 5-HTreceptor agonists
#2731-amino-phthalazine derivatives, the preparation and the therapeutic use thereof
#274Modulators of acetylcholine receptors
#275Muscarinic modulators
#276Androgen receptor modulators and methods of treating disease using the same
#277Process salts compositions and use
#278Benzoimidazolone-carboxamide compounds as 5-HTreceptors agonists
#279Chemokine receptor binding heterocyclic compounds
#280CCR5 antagonists as therapeutic agents
#281Crystalline form of a quinolinone-carboxamide compound
#282Quinolinone compounds as 5-HTreceptor agonists
#283Crystalline form of an indazole-carboxamide compound
#284Benzoxazole carboxamides for treating CINV and IBS-D
#2858-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
#286Indazole-carboxamide compounds
#287Tricyclic δ- opioid modulators
#288Substituted 3-(diarylmethylene)indolin-2-ones and methods of their use
#289Cyclohexyl compounds as CCR5 antagonists
#290Quinolinone-carboxamide compounds
#2915-HTreceptor agonist compounds
#292Pyrimidine derivatives
#293Spiroindoline modulators of muscarinic receptors
#294Heterocyclic compounds as CCR5 antagonists
#295Indane compounds as CCR5 antagonists
#296Compounds with anti-bacterial activity
#297Modulators of muscarinic receptors
#298Nicotinamide derivatives useful as PDE4 inhibitors
#299Androgen receptor modulators and method of treating disease using the same
#300Novel gamma secretase inhibitors