Glucosylceramide synthase inhibitors for the treatment of diseases

Indazole compounds and uses thereof

Process for preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylate and oxalates thereof

Deuterated compounds for treating Fabry, Gaucher, Parkinson's and related diseases and conditions, and compositions and methods thereof

Antibiotics and methods of using same

Chelate compounds

Process for preparing beta-lactamase inhibitor hydroxylurea intermediates

Hormone receptor modulators for treating metabolic conditions and disorders

Isoquinolin-3-yl carboxamides and preparation and use thereof

Heterocyclic compounds and their use in preventing or treating bacterial infections

INTRAESOPHAGEAL ADMINISTRATION OF TARGETED NITROXIDE AGENTS FOR PROTECTION AGAINST IONIZING IRRADIATION-INDUCED ESOPHAGITIS

Azadecalin derivatives as inhibitors of human immunodeficiency virus replication

Beta-lactamase inhibitor compounds

Process for producing crystals of a diazabicyclooctane derivative

Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors

Dual NAV1.2/5HT2a inhibitors for treating CNS disorders

Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders

Avibactam free acid

4-azaindole compounds

1,3-thiazol-2-yl substituted benzamides

TROPOMYOSIN-RELATED KINASE (TRK) INHIBITORS

Bis-benzylidine piperidone proteasome inhibitor with anticancer activity

sGC stimulators

METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C

1,4-substituted piperidine derivatives

Complex and structurally diverse compounds

Amino compounds for treatment of complement mediated disorders

Process for producing organic compound

FACTOR XIA MACROCYCLES WITH NOVEL P1 GROUPS

Therapeutics targeting truncated adenomatous polyposis coli (APC) proteins

THERAPEUTIC INHIBITORY COMPOUNDS

Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them

COMPOUNDS FOR BINDING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9)

Pharmaceutical forms of diazabicyclooctane derivatives and manufacturing method thereof

Heterocyclic compound used as FGFR inhibitor

MYC G-quadruplex stabilizing small molecules and their use

Imaging composition and uses thereof

Polycyclic compound and organic electroluminescence device including the same

Crystalline forms of diazabicyclooctane derivatives and production process thereof

Phosphonate compounds for treatment of complement mediated disorders

DIFLUORO-(2-SUBSTITUTED CARBAMOYL-1,6-DIAZA-BICYCLO [3.2.1] OCT-6-YLOXY) ACETIC ACID COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS

Benzazepine dicarboxamide compounds with tertiary amide function

C3-carbon linked glutarimide degronimers for target protein degradation

COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS

CXCR4 receptor antagonists

PROCESS FOR THE PREPARATION OF LEDIPASVIR AND INTERMEDIATES THEREOF

6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one allosteric modulators of the M4 muscarinic acetylcholine receptor

Inhibitors of lysine specific demethylase-1

Indole derivatives and uses thereof

Ether compounds for treatment of complement mediated disorders

Heteroarylbenzimidazole compounds

Morphinan compounds

Compounds for treatment of complement mediated disorders

Processes for producing diazabicyclooctane compounds

BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS

Therapeutic compounds and methods of use thereof

Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders

Macrocylic ligands with picolinate group(s), complexes thereof and also medical uses thereof

7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide containing compounds and their use in treating bacterial infections

Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof

Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof

FXR RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR, AND USES THEREOF

Methods for treating Huntington's disease

9′-Aza[3,9′-bi(bicyclo[3.3.1]nonan)]-3′-one and preparation thereof

Tank-binding kinase inhibitor compounds

Microbiocidal oxadiazole derivatives

Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof

Biphenyl compound or salt thereof

Pharmaceutical compound

Mono- or di-substituted indole derivatives as dengue viral replication inhibitors

3,6,9, 15-tetraaza-bicyclo [9.3.1 ]pentadeca-1(14), 11(15), 12-triene based compounds and their application as ligands of essential metal ion based MRI and 52MN based PET contrast agents

Factor XIA inhibitors

Morphinan Compounds

Catalyst for the preparation of polyurethanes

Histone deacetylase inhibitors

5-HT3 receptor antagonists

Cyanopyridine derivatives as liver X receptor beta agonists, compositions, and their use

(1R,4R) 7-OXO-2-AZABICYCLO[2.2.2]OCT-5-ENE AND DERIVATIVES THEREOF

Amino-substituted imidazo[1,2-A] pyridinecarboxamides and their use

Nitrogen-containing aromatic heterocyclic compound

Selective NR2B antagonists

Use of cannabinoids and terpenes for treatment of organophosphate and carbamate toxicity

Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors

INHIBITORS OF BRUTONS TYROSINE KINASE

Disubstituted 1, 2, 4-triazine compound

EBNA1 inhibitors and methods using same

2,3-disubstituted 1-acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors

SUBSITUTED ALIPHANES, CYCLOPHANES, HETERAPHANES, HETEROPHANES, HETERO-HETERAPHANES AND METALLOCENES USEFUL FOR TREATING HCV INFECTIONS

Targeted nitroxide agents

Alkyne Compounds for Treatment of Complement Mediated Disorders

ALKYNE COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS

ALKYNE COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS

Combination therapy for treatment of resistant bacterial infections

7-Oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections (changed by PCT to: 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS

Heterocyclic compounds useful as Pim kinase inhibitors

Apelin receptor (APJ) agonists and uses thereof

6,7-cyclicmorphinan derivatives and use thereof

Compositions and methods for inhibition of the JAK pathway

Therapeutic compounds and methods of use thereof

Benzodiazepine derivatives as RSV inhibitors

HIV inhibitor compounds

Processes for preparing a diazabicyclooctane compound

Polycyclic amines as opioid receptor modulators

Heteroaryl compounds as IRAK inhibitors and uses thereof

HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF

Substituted glycine derived FXIA inhibitors

Tyrosine amide derivatives as Rho-kinase inhibitors

Histone deacetylase inhibitors

Bridged bicyclic kallikrein inhibitors

Compositions and methods for inhibiting β-lactamase

Heterobicyclic N-aminophenyl-amides as inhibitors of histone deacetylase

Pyrimidinones as factor XIa inhibitors

6-(5-hydroxy-1H-pyrazol-1-yl)nicotinamide inhibitors of PHD

Inhibitors of lysine specific demethylase-1

1,4-substituted piperidine derivatives

KRAS G12C inhibitors and methods of using the same

Amino compounds for treatment of medical disorders

1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their bacterial infections

Inhibitors of leukotriene A4 hydrolase

FACTOR XIA MACROCYCLES WITH NOVEL P1 GROUPS

Compounds useful as inhibitors of ATR kinase

Macrocycles as factor XIa inhibitors

Substituted-Quinoxaline-Type Bridged-Piperidine Compounds and the Uses Thereof

β-lactamase inhibitors and uses thereof

BIHETEROARYL COMPOUNDS AND USES THEREOF

Morphinan derivatives for the treatment of neuropathic pain

Therapeutic compounds

1,3-thiazol-2-yl substituted benzamides

BIHETEROARYL COMPOUNDS AND USES THEREOF

Heterocyclic morphinan derivatives and use thereof

Diazabicyclooctane compounds

Heterocyclic compounds and their use in preventing or treating bacterial infections

1,3-thiazol-2-yl substituted benzamides

Heterocyclic compounds and their use in preventing or treating bacterial infections

Heterocyclic compounds and their use in preventing or treating bacterial infections

Process for the synthesis of E1 activating enzyme inhibitors

Inhibitors of indoleamine-2,3-dioxygenase for the treatment of cancer

5HT3 RECEPTOR ANTAGONISTS

Compounds useful as inhibitors of ATR kinase

1,3-thiazol-2-yl substituted benzamides

Inhibitors of indoleamine-2,3-dioxygenase for the treatment of cancer

Glucosylceramide synthase inhibitors

1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as MAGL inhibitors

Morphinan derivative

Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero- heteraphanes and metallocenes useful for treating HCV infections

Heterocyclic compounds and uses thereof

Pyridinones and isoquinolinones as inhibitors of the bromodomain BRD9

Azepane derivatives and methods of treating hepatitis B infections

TLR7/8 antagonists and uses thereof

Ethylenediaminetetraacetic acid bis(amide) derivatives and their respective complexes with Mn(II) ion for use as MRI contrast agent

MYC G-quadruplex stabilizing small molecules and their use

Autotaxin inhibitors

Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity

AMINOESTER DERIVATIVES

Tricyclic compounds as inhibitors of mutant IDH enzymes

Process for the preparation of tert-butyl 4-((2S ,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)piperidine-1-carboxylate and analogs thereof

Quinazoline derivatives substituted by aniline, preparation method and use thereof

Lyophilized composition of a diazabicyclooctane compound and process of producing the same

Imaging composition and uses thereof

Bridged diazepane orexin receptor antagonists

Methods for treatment of resistant cancer

Methods of producing heteropolycycles via bis-epoxidation

STA-18, a new member of the SFW family of molecular sieve zeotypes, methods of preparation and use

QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF

Carbamate, ester, and ketone compounds for treatment of complement mediated disorders

Amide compounds for treatment of complement mediated disorders

FXR (NR1H4) modulating compounds

1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions

Process for producing diazabicyclooctane derivative

Benzenesulfonyl-asymmetric ureas and medical uses thereof

6-(5-hydroxy-1H-pyrazol-1-YL)nicotinamide inhibitors of PHD

Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C

5-HT3 receptor antagonists

Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer

Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides

Beta-lactamase inhibitor and process for preparing the same

IDO inhibitors

Factor D Inhibitors Useful for Treating Inflammatory Disorders

CXCR4 receptor antagonists

Tropomyosin-related kinase (Trk) inhibitors

Antidiabetic bicyclic compounds

NOVEL CRYSTALLINE FORMS OF TRANS-7-OXO-6-(SULPHOOXY)-1,6-DIAZABICYCLO[3,2,1]OCTANE-2-CARBOXAMIDE SODIUM SALT

Electroconductive member for electrophotography and quaternary ammonium salt

Pyrimidine carboxamides as sodium channel blockers

Substituted 2-azabicycles and their use as orexin receptor modulators

Heterocyclic compounds having cholesterol 24-hydroxylase activity

Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo [3.2.1]-octane

Process for the preparation of Ledipasvir

Therapeutic compounds and methods of use thereof

Amino compounds for treatment of complement mediated disorders

6,7-dihydro-5H-pyrrolo[3,4-B]pyridin-5-one allosteric modulators of the M4 muscarinic acetylcholine receptor

Process for preparation of sodium (2S, 5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate

Apelin receptor (APJ) agonists and uses thereof

Macrocycles as factor XIa inhibitors

Pyrimidinone derivative having autotaxin-inhibitory activity

MULTIVALENT RAS BINDING COMPOUNDS

Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity

Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for treating HCV infections

NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND

Compositions and methods for inhibition of the JAK pathway

sGC stimulators

Synthesis of hetero ionic compounds using dialkylcarbonate quaternization

Heterocyclic compounds and methods of use thereof

Azamorphinan derivatives and use thereof

Compounds useful as immunomodulators

Substituted prolines/piperidines as orexin receptor antagonists

Compositions and methods for inhibiting beta-lactamase

Macrocycles with aromatic P2′ groups as factor xia inhibitors

Heterocyclic compounds useful as pim kinase inhibitors

Heteroaryl compounds as IRAK inhibitors and uses thereof

Heteroaryl compounds as IRAK inhibitors and uses thereof

Organic electroluminescent device

Substituted spirocycles

Amide compounds for treatment of medical disorders

Benzimidazole derivatives useful as CB-1 inverse agonists

Heteroaryl compounds useful as inhibitors of E1 activating enzymes

Histone deacetylase inhibitors

7-OXO-1,6-diazabicyclo[3.2.1]octane derivatives and their use as antibacterial agents

Disubstituted 1, 2, 4-triazine compound

Morphinan compounds

Antiviral compounds

1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as MAGL inhibitors

Benzodiazepine derivatives as RSV inhibitors

Processes for preparing heterocyclic compounds including trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide and salts thereof

Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof

Substituted 2-azabicycles and their use as orexin receptor modulators

Process for preparation of sodium (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate

Peripherally acting opioid compounds

Peripheral opioid receptor antagonists and uses thereof

Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for treating HCV infections

Use of metal complexes which are mimetics of SOD as food agents and as cosmetics

ADO-resistant cysteamine analogs and uses thereof

Diazabicyclo[4.3.1]decane derivatives for treatment of psychiatric disorders

Factor XIa inhibitors

sGC stimulators

Donor-acceptor nanohoop compounds and methods of making and using the same

PYRIMIDINONES AS FACTOR XIA INHIBITORS

1,4-substituted piperidine derivatives

Bridged bicyclic kallikrein inhibitors

Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain

Nitrogen containing compounds and their use as antibacterial agents

Factor XIa inhibitors

Compounds useful as inhibitors of ATR kinase

sGC stimulators

Dihydropyridone P1 as factor XIa inhibitors

Process for preparation of (2S,5R)-6-sulphooxy-7-oxo-2-[((3R)-piperidine-3-carbonyl)-hydrazinocarbonyl]-1,6-diaza-bicyclo[3.2.1] octane

Benzimidazole and imadazopyridine carboximidamide compounds

Kinase inhibitor and use thereof

Aminoester derivatives

PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS

1,6- DIAZABICYCLO [3,2,1] OCTAN-7-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS

Inhibitors of lysine specific demethylase-1

Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors

2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1 ]octane derivatives and their use as antibacterial agents

Dihydropyrazole GPR40 modulators

Substituted quinazoline compounds and methods of use thereof

N-substituted benzamides and methods of use thereof

Polymorphs and process for preparation of (2, 5)-7-oxo-N-[(2)-pyrrolidin-2-yl-methyloxy]-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide

Processes for producing diazabicyclooctane compounds

Substituted piperidin-4-amino-type compounds and uses thereof

Process for producing diazabicyclooctane derivative and intermediate thereof

Heteroaryl compounds as BTK inhibitors and uses thereof

Super-oxide dismutase mimetics

Nitrogen containing compounds and their use

FUNCTIONALIZED FURAN-2-SULFONAMIDES EXHIBITING ENDOTHELIAL LIPASE INHIBITION

5-HT3 receptor antagonists

6-(5-hydroxy-1H-pyrazol-1-yl)nicotinamide inhibitors of PHD

Beta lactams as modulators of glutamate uptake and methods for use thereof

Glucosylceramide synthase inhibitors for the treatment of diseases

Dibenzo[B,F][1,4]oxazepin-11-yl-N-Hydroxybenzamides as HDAC Inhibitors

3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use

3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS

Triazine compounds and compositions thereof and methods for treating malaria and chemoprophylaxis

1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections

Polycyclic compounds

Method for producing endo-9-azabicyclo[3.3.1]nonan-3-ol derivative

Aromatic heterocyclylamine derivative having TRPV4-inhibiting activity

5-HT3 receptor antagonists

Anthelmintic compounds and compositions and method of using thereof

Autotaxin inhibitors

Heterocyclyl pyrimidine analogues as TYK2 inhibitors

N-cyanomethylamides as inhibitors of janus kinase

β-lactamase inhibitor compounds

Substituted-quinoxaline-type piperidine compounds and the uses thereof

Mixtures of heteropolycycles

Electrochromic iptycenes

Targeted nitroxide agents

Compounds useful for producing an optically active diazabicyclooctane compound

BICYCLO 2,3-BENZODIAZEPINES AND SPIROCYCLICALLY SUBSTITUTED 2,3-BENZODIAZEPINES

6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

Process for the preparation of chiral tert-butyl 4-((1R,2S,5R)-6(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)piperidine-1-carb derivatives and (2S,5R)-7-oxo-N-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide

Morphinan derivative

Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for treating HCV infections

Peripheral opioid receptor antagonists and uses thereof

Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for treating HCV infections

Tricyclic indole Mcl-1 inhibitors and uses thereof

Bis-benzylidine piperidone proteasome inhibitor with anticancer activity

Unsaturated nitrogen heterocyclic compounds useful as PDE10 inhibitors

Pyrimidinones as factor XIa inhibitors

Tank-binding kinase inhibitor compounds