ClassID:

95363

C07D471/08 - page 2 - CPC Classification

Classification description:

Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups  -  in which the condensed system contains two hetero rings Bridged systems

Recent Application in this class:
#301
20230002381
2023-01-05

Small molecule inhibitors targeting sporulation

#302
20230002380
2023-01-05

NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST GLUCOSYLCERAMIDE SYNTHASE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

#303
20230002379
2023-01-05

NOVEL DERIVATIVES HAVING 2,3-DIHYDRO-1H-INDENE OR 2,3-DIHYDROBENZOFURAN MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

#304
20230002367
2023-01-05

BIFUNCTIONAL COMPOUNDS

#305
20230002362
2023-01-05

BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF

#306
20220411442
2022-12-29

Polycyclic amines as sigma receptor modulators

#307
20220403383
2022-12-22

METHODS AND COMPOSITIONS FOR MODULATING SPLICING

#308
20220402950
2022-12-22

SUBSTITUTED BENZIMIDAZOLES AS PAD4 INHIBITORS

#309
20220402909
2022-12-22

NOVEL DERIVATIVES HAVING 1,2,3,4-TETRAHYDRONAPHTHALENE MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

#310
20220401856
2022-12-22

Chromatographic separation of metals using DOTA-based chelators

#311
20220396563
2022-12-15

Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders

#312
20220396562
2022-12-15

Cycloalkyl pyrimidines as ferroportin inhibitors

#313
20220388992
2022-12-08

JAK INHIBITOR COMPOUND AND USE THEREOF

#314
20220387428
2022-12-08

1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS

#315
20220380345
2022-12-01

HOMOPIPERAZINYL AND HOMOPIPERIDINYL QUINAZOLIN-4(3H)-ONE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

#316
20220380319
2022-12-01

SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

#317
20220380314
2022-12-01

SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

#318
20220378759
2022-12-01

Nitrogen containing bicyclic compounds

#319
20220372038
2022-11-24

Heterocyclic compounds and uses thereof

#320
20220363681
2022-11-17

OXO SIX-MEMBERED CYCLOPYRIMIDINE COMPOUND, PREPARATION METHOD AND MEDICAL USE THEREOF

#321
20220363676
2022-11-17

Compounds and methods for modulating Interleukin-2-inducible T-cell kinase

#322
20220363666
2022-11-17

TYROSINE KINASE INHIBITOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE

#323
20220363665
2022-11-17

QUINOLINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

#324
20220356176
2022-11-10

Kv11.1-3.1 INHIBITING METHODS AND COMPOSITIONS

#325
20220348578
2022-11-03

Crystalline forms of diazabicyclooctane derivative and production process thereof

#326
20220348577
2022-11-03

CXCR4 Receptor Antagonists

#327
20220348564
2022-11-03

PHENYL-[1,3]DIOXOLO[4,5-C]PYRIDINYL-PHENYL-, PHENYL-[1,3]DIOXOLO[4,5-C]PYRIDINYL-HETEROARYL-, OR PHENYL-(1,3)DIOXO[4,5-C]PYRIDINYL-PIPERIDINYL-METHYL-OXETANYLMETHYL-1H-BENZO[D]IMIDAZOLE-CARBOXYLIC ACID DERIVATIVES AND METHODS OF USING SAME

#328
20220347175
2022-11-03

PYRIDAZINONE DERIVATIVE

#329
20220340555
2022-10-27

4-azaindole compounds

#330
20220340547
2022-10-27

INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

#331
20220332698
2022-10-20

Isoquinolin-3-yl carboxamides and preparation and use thereof

#332
20220331299
2022-10-20

Substituted 2-azabicyclo[3.1.1]heptane and 2-azabicyclo[3.2.1]octane derivatives as orexin receptor antagonists

#333
20220324835
2022-10-13

INHIBITORS OF CBL-B AND METHODS OF USE THEREOF

#334
20220315564
2022-10-06

Methods and compounds for restoring mutant p53 function

#335
20220315563
2022-10-06

ALK-5 inhibitors and uses thereof

#336
20220315549
2022-10-06

HETEROAROMATIC ACETAMIDE DERIVATIVE, AND PREPARATION AND USE THEREOF

#337
20220315548
2022-10-06

SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF

#338
20220313826
2022-10-06

C-carbon linked glutarimide degronimers for target protein degradation

#339
20220298155
2022-09-22

COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING

#340
20220298144
2022-09-22

BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF

#341
20220298120
2022-09-22

ALKYNYL QUINAZOLINE COMPOUNDS

#342
20220289748
2022-09-15

METHOD FOR PRODUCING PHENOL DERIVATIVE

#343
20220289747
2022-09-15

Diazabicyclooctanones as inhibitors of serine beta-lactamases

#344
20220289710
2022-09-15

2-amino-N-heteroaryl-nicotinamides as Na1.8 inhibitors

#345
20220289708
2022-09-15

SUBSTITUTED N-PHENYL URACILS, SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS

#346
20220288074
2022-09-15

Compounds for the treatment of BRAF-associated diseases and disorders

#347
20220281843
2022-09-08

KIF18A INHIBITORS

#348
20220281825
2022-09-08

HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION

#349
20220267328
2022-08-25

Azabicyclo and diazepine derivatives

#350
20220267327
2022-08-25

Method for producing morphinan derivative

#351
20220259201
2022-08-18

INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF

#352
20220251084
2022-08-11

PROGRANULIN MODULATORS AND METHODS OF USING THE SAME

#353
20220251075
2022-08-11

Cycloalkyl and Heterocycloalkyl Benzisoxazole Sulfonamide Derivatives

#354
20220249411
2022-08-11

CALIXARENE COMPOUNDS AND USES THEREOF

#355
20220227745
2022-07-21

Compounds For Modulating FXR

#356
20220194942
2022-06-23

3,6-methano-1H-pyrrolo[3,2-b]pyridine and 3,6-methano-1H-pyrrolo[3,2-c]pyridine compounds and medicaments using same

#357
20220194941
2022-06-23

Process for the preparation of intermediates useful for making (2S,5R)-7-oxo-n-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide

#358
20220177625
2022-06-09

Curable composition, cured product, and compound

#359
20220168280
2022-06-02

KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

#360
20220162191
2022-05-26

SMALL MOLECULE MODULATORS OF IL-17

#361
20220153739
2022-05-19

OPIOID RECEPTOR MODULATOR AND USE THEREOF

#362
20220151981
2022-05-19

Methods of treating sarin exposure with tetrahydrocannabinol and cannabidiol combinations

#363
20220143002
2022-05-12

SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF

#364
20220106329
2022-04-07

BICYCLIC ROR-GAMMA MODULATORS

#365
20220098168
2022-03-31

METHODS AND COMPOSITIONS FOR SCREENING AND IDENTIFICATION OF SPLICING MODULATORS

#366
20220087996
2022-03-24

Histone acetylase p300 inhibitor and use thereof

#367
20220081426
2022-03-17

Preparation of seimicarbazide-sensitive amine oxidase inhibitor and use thereof

#368
20220081412
2022-03-17

QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF

#369
20220073508
2022-03-10

Glucosylceramide synthase inhibitors

#370
20220064513
2022-03-03

Reservoir drilling fluids consist of cationic heterocyclic polymers, synthesis, formulation, and applications

#371
20220064112
2022-03-03

EBNA1 inhibitors and methods using same

#372
20220056029
2022-02-24

Cathinone derivatives, pharmaceutical formulations, and methods

#373
20220041601
2022-02-10

PYRIMIDINONES AS FACTOR XIA INHIBITORS

#374
20220041599
2022-02-10

METHODS AND COMPOSITIONS FOR MODULATING SPLICING

#375
20220024920
2022-01-27

ADO-resistant cysteamine analogs and uses thereof

#376
20220024901
2022-01-27

GLP-1R AGONISTS AND USES THEREOF

#377
20220024895
2022-01-27

METHODS AND COMPOSITIONS FOR SCREENING AND IDENTIFICATION OF SPLICING MODULATORS

#378
20220021031
2022-01-20

ELECTROLYTE ADDITIVE, ELECTROLYTE, LITHIUM ION SECONDARY BATTERY CONTAINING THE SAME AND USE THEREOF

#379
20220017517
2022-01-20

Substituted piperidine compounds and their use

#380
20220017516
2022-01-20

LOX INHIBITORS

#381
20220017504
2022-01-20

Quinolinone and benzoxazine derivatives as muscarinic Mand/or Mreceptor agonists

#382
20220016613
2022-01-20

Annulation catalysts via direct C—H bond amination

#383
20220009926
2022-01-13

Ester and carbonate pyrimidine compounds as JAK kinase inhibitors

#384
20210403457
2021-12-30

2-oxoimidazolidine-4-carboxamides as NA1.8 inhibitors

#385
20210393599
2021-12-23

MODULATORS OF THE INTEGRATED STRESS PATHWAY

#386
20210387986
2021-12-16

Inhibitors of integrin alpha 2 beta 1 and methods of use

#387
20210387967
2021-12-16

2-heteroaryl aminoquinazolinone derivative

#388
20210387966
2021-12-16

2-AMINO-N-HETEROARYL-NICOTINAMIDES AS NAV1.8 INHIBITORS

#389
20210387963
2021-12-16

Phenyltetrazole derivatives as plasma kallikrein inhibitors

#390
20210380585
2021-12-09

Hormone receptor modulators for treating metabolic mutagenic and fibrotic conditions and disorders

#391
20210380578
2021-12-09

Multicyclic compounds as farnesoid X receptor modulators

#392
20210379055
2021-12-09

Substituted alkynylene compounds as anticancer agents

#393
20210371460
2021-12-02

TARGETED NITROXIDE AGENTS

#394
20210371419
2021-12-02

Processes for preparing a diazabicyclooctane compound

#395
20210363139
2021-11-25

CXCR4 INHIBITORS AND USES THEREOF

#396
20210363098
2021-11-25

Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation

#397
20210361782
2021-11-25

Complex of gadolinium and a chelating ligand derived of a diastereoisomerically enriched PCTA and synthesis method

#398
20210355126
2021-11-18

Fused pyrrolines which act as ubiquitin-specific protease 30 (USP30) inhibitors

#399
20210355122
2021-11-18

Pyrazolopyridine compounds for the treatment of autoimmune disease

#400
20210348208
2021-11-11

Morphinan compounds

#401
20210340136
2021-11-04

Benzothiazole compounds for the treatment of autoimmune diseases

#402
20210323977
2021-10-21

PYRROLIDINYL AMIDE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

#403
20210317102
2021-10-14

INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY

#404
20210300928
2021-09-30

Methods and compositions for substituted arylcycloheptane analogs

#405
20210300927
2021-09-30

Isoxazolyl-carbonyloxy azabicyclo[3.2.1]octanyl compounds as FXR activators

#406
20210300926
2021-09-30

NEW BETA-LACTAMASE INHIBITORS TARGETING GRAM NEGATIVE BACTERIA

#407
20210276975
2021-09-09

Inhibitors of (α-v)(β-6) integrin

#408
20210275526
2021-09-09

Methods for treating Huntington's disease

#409
20210275499
2021-09-09

Heterocyclic sulfonamide derivatives and pharmaceutical uses thereof

#410
20210261537
2021-08-26

INHIBITORS OF SARM1

#411
20210261516
2021-08-26

MYC G-QUADRUPLEX STABILIZING SMALL MOLECULES AND THEIR USE

#412
20210260027
2021-08-26

METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C

#413
20210253575
2021-08-19

PYRROLIDINE AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

#414
20210251991
2021-08-19

SUBSTITUTED 2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME

#415
20210238177
2021-08-05

CRYSTALLINE FORMS OF 3-((1R,5S,9r)-9-ETHOXY-3-AZABICYCLO[3.3.1]NONAN-9-YL)-BENZAMIDE AND SALT FORMS THEREOF

#416
20210230146
2021-07-29

Thyroid hormone receptor agonists and use thereof

#417
20210230116
2021-07-29

1,4-substituted piperidine derivatives

#418
20210221805
2021-07-22

SIGMA-2 RECEPTOR LIGAND DRUG CONJUGATES AS ANTITUMOR COMPOUNDS, METHODS OF SYNTHESIS AND USES THEREOF

#419
20210221790
2021-07-22

ABHD12 inhibitors and methods of making and using same

#420
20210214356
2021-07-15

3,6-methano-1H-pyrrolo[3,2-b]pyridine and 3,6-methano-1H-pyrrolo[3,2-C]pyridine compounds and medicaments using same

#421
20210196840
2021-07-01

Gadolinium bearing PCTA-based contrast agents

#422
20210188857
2021-06-24

SOS1 inhibitors

#423
20210188827
2021-06-24

ATM kinase inhibitors and compositions and methods of use thereof

#424
20210179616
2021-06-17

Azabicyclo and diazepine derivatives

#425
20210171521
2021-06-10

Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection

#426
20210171519
2021-06-10

Methods and compositions for modulating splicing

#427
20210171462
2021-06-10

Mono- or di-substituted indole derivatives as dengue viral replication inhibitors

#428
20210169894
2021-06-10

Tropomyosin-related kinase (TRK) inhibitors

#429
20210163447
2021-06-03

Tyrosine kinase inhibitor compositions, methods of making and methods of use

#430
20210147382
2021-05-20

Benzimidazolone derived inhibitors of BCL6

#431
20210139494
2021-05-13

Heterocyclic RIP1 inhibitory compounds

#432
20210114983
2021-04-22

Cathepsin C inhibitors

#433
20210087174
2021-03-25

Aryl and heteroaryl substituted indole compounds

#434
20210078991
2021-03-18

THERAPEUTIC COMPOUNDS

#435
20210078947
2021-03-18

Therapeutic compounds and methods of use thereof

#436
20210070767
2021-03-11

Apelin receptor (APJ) agonists and uses thereof

#437
20210070751
2021-03-11

Substituted indole ether compounds

#438
20210070748
2021-03-11

INHIBITORS OF BRUTONS TYROSINE KINASE

#439
20210070744
2021-03-11

Heterocyclic RIP1 kinase inhibitors

#440
20210070743
2021-03-11

RIP1 inhibitory compounds and methods for making and using the same

#441
20210070735
2021-03-11

RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME

#442
20210061761
2021-03-04

Modulators of complex I

#443
20210054171
2021-02-25

Urea-glyoxal crosslinking compounds for phenolic binder compositions

#444
20210054007
2021-02-25

Receptor inhibitor, pharmaceutical composition comprising same, and use thereof

#445
20210053997
2021-02-25

TRNA synthetase inhibitors

#446
20210053987
2021-02-25

Bicyclic RORγ modulators

#447
20210053945
2021-02-25

Acryloyl-containing nuclear transport regulators and uses thereof

#448
20210047340
2021-02-18

SREBP inhibitors comprising a 6-membered central ring

#449
20210047333
2021-02-18

Compounds useful as inhibitors of ATR kinase

#450
20210047323
2021-02-18

Crystalline forms of CFTR modulators

#451
20210047294
2021-02-18

Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors

#452
20210047293
2021-02-18

Heterocyclic P2Yreceptor antagonists

#453
20210046073
2021-02-18

2,3-disubstituted 1-acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors

#454
20210046057
2021-02-18

Beta-lactamase inhibitor and use thereof

#455
20210040094
2021-02-11

Morphinan derivative

#456
20210040085
2021-02-11

Imidazole and triazole containing bicyclic compounds as JAK inhibitors

#457
20210040079
2021-02-11

10H-phenothiazine ferroptosis inhibitor as well as the preparative method and the use thereof

#458
20210032260
2021-02-04

β-lactamase inhibitor and use thereof

#459
20210032214
2021-02-04

Compounds for binding proprotein convertase subtilisin/kexin type 9

#460
20210024525
2021-01-28

Compounds for treating Huntington's disease

#461
20210024522
2021-01-28

FXR agonist

#462
20210024494
2021-01-28

PD-1/PD-L1 inhibitors

#463
20210017180
2021-01-21

Pyclen-based macrocyclic ligands, chelates thereof and uses thereof

#464
20210017179
2021-01-21

Short conjugated oligoelectrolytes and uses thereof

#465
20210017178
2021-01-21

Pan-tropic entry inhibitors

#466
20210017177
2021-01-21

HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS

#467
20210009591
2021-01-14

Pyrazole derivative compound and use thereof

#468
20210009590
2021-01-14

Compounds for treating huntington's disease

#469
20210009588
2021-01-14

Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors

#470
20210008031
2021-01-14

SUPER-OXIDE DISMUTASE MIMETICS

#471
20210002298
2021-01-07

Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors

#472
20210002288
2021-01-07

Indazole compounds and uses thereof

#473
20210002261
2021-01-07

Sulphonyl urea derivatives as NLRP3 inflammasome modulators

#474
20210002256
2021-01-07

TLR7/8 ANTAGONISTS AND USES THEREOF

#475
20210002255
2021-01-07

TLR7/8 antagonists and uses thereof

#476
20210002250
2021-01-07

Substituted benzodiazoles and use thereof in therapy

#477
20200407360
2020-12-31

Process for producing fluorinated compounds using alcohol solvent having unsaturated hydrocarbon

#478
20200399261
2020-12-24

Inhibitors of protein arginine methyltransferase 5 (PRMT5), pharmaceutical products thereof, and methods thereof

#479
20200392134
2020-12-17

METHOD FOR PURIFYING 2-[[2-[[[3-(4-CHLOROPHENYL)-8-METHYL-8-AZABICYCLO-[3.2.1]-OCT-2-YL]METHYL](2-MERCAPTOETHYL)AMINO]ETHYL]AMINO]ETHANETHIOL-[1R-(EXO-EXO)]TRIHYDROCHLORIDE

#480
20200385385
2020-12-10

Crystal form of β-lactamase inhibitor and preparation method therefor

#481
20200375940
2020-12-03

Cannabinoid co-drug compounds

#482
20200361936
2020-11-19

MORPHINAN DERIVATIVES AND USE THEREOF

#483
20200361895
2020-11-19

NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS

#484
20200354342
2020-11-12

2-(1H-pyrazol-3-yl) phenol compound and use thereof

#485
20200347078
2020-11-05

Heterocyclylmethylidene derivatives and their use as modulators of mGluR5 receptors

#486
20200347060
2020-11-05

Process for the preparation of umeclidinium bromide

#487
20200345732
2020-11-05

1,4-disubstituted pyridazine analogs thereof and methods for treating SMN-deficiency-related conditions

#488
20200339580
2020-10-29

Ester and carbonate pyrimidine compounds as JAK kinase inhibitors

#489
20200339507
2020-10-29

Methods of synthesizing aztreonam derivatives

#490
20200338073
2020-10-29

Pyrimidine JAK inhibitors for the treatment of skin diseases

#491
20200325139
2020-10-15

NEW ANTIBIOTICS TARGETING MYCOBACTERIA

#492
20200325119
2020-10-15

Quinolone compounds as inhibitors of the BCL6 BTB domain protein-protein interaction and/or as BCL6 degraders

#493
20200317730
2020-10-08

TARGETED NITROXIDE AGENTS

#494
20200316065
2020-10-08

sGC stimulators

#495
20200308196
2020-10-01

Organic electroluminescent materials and devices

#496
20200308168
2020-10-01

FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2

#497
20200308163
2020-10-01

Compounds and compositions as modulators of TLR signaling

#498
20200308128
2020-10-01

MYC G-quadruplex stabilizing small molecules and their use

#499
20200299296
2020-09-24

Analogs of 3-amino-4-(propan-2-ylidene)cyclopentane-1-carboxylic acid and uses thereof for treating diseases and disorders associated with ornithine aminotransferase activity

#500
20200299277
2020-09-24

Piperazine derivatives as MAGL inhibitors

#501
20200299263
2020-09-24

Isoquinolin-3-YL carboxamides and preparation and use thereof

#502
20200297733
2020-09-24

BETA-LACTAMASE INHIBITORS AND USES THEREOF

#503
20200297710
2020-09-24

Chemical compounds

#504
20200291022
2020-09-17

Crystalline form of an avibactam derivative

#505
20200291003
2020-09-17

Sulfonamide carboxamide compounds

#506
20200290998
2020-09-17

Imidazole-pyrazole derivatives

#507
20200283430
2020-09-10

Alkene compounds as farnesoid x receptor modulators

#508
20200283427
2020-09-10

Muscarinic agonists as non-steroidal and non-opioid analgesics and methods of use thereof

#509
20200283424
2020-09-10

GLP-1R agonists and uses thereof

#510
20200281913
2020-09-10

Metallo-beta-lactamase inhibitors and methods of use thereof

#511
20200277289
2020-09-03

Methods and compositions for modulating splicing

#512
20200270209
2020-08-27

Mono- or di-substituted indole derivatives as dengue viral replication inhibitors

#513
20200262813
2020-08-20

1,5,7-TRISUBSTITUTED ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES

#514
20200255414
2020-08-13

CXCR4 inhibitors and uses thereof

#515
20200247799
2020-08-06

Methods and compositions for modulating splicing

#516
20200247760
2020-08-06

Compounds, compositions and methods for treatment of myopia

#517
20200246286
2020-08-06

Imaging composition and uses thereof

#518
20200239415
2020-07-30

EBNA1 inhibitors and methods using same

#519
20200231590
2020-07-23

Imidazole and triazole containing bicyclic compounds as JAK inhibitors

#520
20200231551
2020-07-23

Compositions and uses thereof

#521
20200224199
2020-07-16

Methods and compositions for modulating splicing

#522
20200223867
2020-07-16

Benzodiazepine derivatives as RSV inhibitors

#523
20200223847
2020-07-16

Pharmaceutical salts of substituted-quinoxaline-type bridged-piperidine compounds

#524
20200216431
2020-07-09

COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY

#525
20200188397
2020-06-18

Biheteroaryl compounds and uses thereof

#526
20200181143
2020-06-11

Crystalline forms of diazabicyclooctane derivative and production process thereof

#527
20200172492
2020-06-04

Pharmaceutical compound

#528
20200171029
2020-06-04

BIHETEROARYL COMPOUNDS AND USES THEREOF

#529
20200157099
2020-05-21

3,6,9, 15-tetraaza-bicyclo [9.3.1]pentadeca-1(14), 11(15), 12-triene based compounds and their application as ligands of essential metal ion based MRI and 52MN based PET contrast agents

#530
20200157094
2020-05-21

PD-1/PD-L1 inhibitors

#531
20200157075
2020-05-21

Inhibitors of (α-v)(β-6) integrin

#532
20200148704
2020-05-14

HISTONE DEACETYLASE INHIBITORS

#533
20200148696
2020-05-14

Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof

#534
20200147243
2020-05-14

LIGAND COMPOUND OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AND APPLICATION THEREOF

#535
20200140451
2020-05-07

Englerin derivatives for treatment of cancer

#536
20200140441
2020-05-07

Compounds useful as inhibitors of ATR kinase

#537
20200140411
2020-05-07

2-amino-n-heteroaryl-nicotinamides as Na1.8 inhibitors

#538
20200138780
2020-05-07

METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C

#539
20200131169
2020-04-30

1,3-thiazol-2-yl substituted benzamides

#540
20200131167
2020-04-30

Diamino-alkylamino-linked arylsulfonamide compounds with selective activity in voltage-gated sodium channels

#541
20200123155
2020-04-23

Macrocyclic ligands with picolinate group(s), complexes thereof and also medical uses thereof

#542
20200123149
2020-04-23

Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof

#543
20200123132
2020-04-23

ANTIVIRAL COMPOUNDS

#544
20200121657
2020-04-23

Substituted methanopyrido [2, 1-a] isoindolones as mAChR modulators for treating various associated pathophysiological conditions and process for preparation thereof

#545
20200113904
2020-04-16

Methods for treating Huntington's disease

#546
20200102307
2020-04-02

Derivatives of relebactam and uses thereof

#547
20200095247
2020-03-26

4-Azaindole compounds

#548
20200087299
2020-03-19

Inhibitors of (alpha-v)(beta-6) integrin

#549
20200079775
2020-03-12

Morphinan derivative

#550
20200079774
2020-03-12

Tyrosine amide derivatives as Rho-Kinase inhibitors

#551
20200071328
2020-03-05

1,6- DIAZABICYCLO [3,2,1] OCTAN-7-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS

#552
20200071304
2020-03-05

Selective NR2B antagonists

#553
20200071301
2020-03-05

Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders

#554
20200069657
2020-03-05

KRAS G12C inhibitors and methods of using the same

#555
20200062790
2020-02-27

Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders

#556
20200055854
2020-02-20

Pyrimidinones as factor XIA inhibitors

#557
20200055852
2020-02-20

Five-membered heteroaryl ring bridged ring derivative, preparation method therefor and medical use thereof

#558
20200054617
2020-02-20

Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors

#559
20200048253
2020-02-13

Processes for preparing a diazabicyclooctane compound

#560
20200046724
2020-02-13

Beta-lactamase inhibitors and uses thereof

#561
20200031826
2020-01-30

Hydrocodone base and methods for its purification

#562
20200024278
2020-01-23

COMPOSITION COMPRISING ANTIBIOTIC COMPOUND AND AN HETEROCYCLIC COMPOUND AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS

#563
20200022975
2020-01-23

Morphinan compounds

#564
20200017496
2020-01-16

NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS

#565
20200017495
2020-01-16

NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS

#566
20200017471
2020-01-16

PD-1/PD-L1 inhibitors

#567
20200016136
2020-01-16

PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

#568
20200010467
2020-01-09

β-lactamase inhibitors

#569
20200010419
2020-01-09

Nanohoop compound embodiments comprising meta-substitution and molecular systems comprising the same

#570
20200009090
2020-01-09

Imaging composition and uses thereof

#571
20200002348
2020-01-02

Heterocyclic derivatives for the treatment of cystic fibrosis

#572
20200002309
2020-01-02

Heterocyclic compounds useful as Pim kinase inhibitors

#573
20190382378
2019-12-19

Substituted glycine derived FXIA inhibitors

#574
20190382359
2019-12-19

1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as MAGL inhibitors

#575
20190375743
2019-12-12

Compounds and methods for modulating interleukin-2-inducible t-cell kinase

#576
20190374526
2019-12-12

Substituted Heterocyclic Compounds as Inhibitors of PRDM9

#577
20190367521
2019-12-05

HETEROCYCLIC COMPOUNDS AND USES THEREOF

#578
20190367495
2019-12-05

Antidiabetic heterocyclic compounds

#579
20190359612
2019-11-28

Process for the preparation of crystalline form C of avibactam sodium

#580
20190358226
2019-11-28

1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions

#581
20190352280
2019-11-21

Compounds useful as immunomodulators

#582
20190337929
2019-11-07

Indolinones compounds and their use in the treatment of fibrotic diseases

#583
20190337926
2019-11-07

BMP-signal-inhibiting compound

#584
20190337911
2019-11-07

Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them

#585
20190330208
2019-10-31

Morphinan derivatives and use thereof

#586
20190328704
2019-10-31

SUPER-OXIDE DISMUTASE MIMETICS

#587
20190315715
2019-10-17

Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme

#588
20190308983
2019-10-10

HIV inhibitor compounds

#589
20190308973
2019-10-10

Isoxazolyl-carbonyloxy azabicyclo[3.2.1]octanyl compounds as FXR activators

#590
20190308938
2019-10-10

Heterocyclic compounds for the treatment of arenavirus

#591
20190298705
2019-10-03

Chemical Compounds

#592
20190292133
2019-09-26

Chiral phase-transfer catalyst and method for preparing alpha-amino acid by using the same

#593
20190284226
2019-09-19

Thionyl tetrafluoride modified compounds and uses

#594
20190284144
2019-09-19

Substituted quinazoline compounds and methods of use thereof

#595
20190276434
2019-09-12

IRE1 small molecule inhibitors

#596
20190270749
2019-09-05

Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain

#597
20190263814
2019-08-29

Process for the preparation of umeclidinium bromide

#598
20190263813
2019-08-29

Simple process for preparing an intermediate for avibactam

#599
20190263812
2019-08-29

Process for preparing an intermediate for avibactam

#600
20190263811
2019-08-29

Crystalline forms