ClassID:

96976

C07K14/55 - page 2 - CPC Classification

Classification description:

Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans; Cytokines; Lymphokines; Interferons; Interleukins [IL] IL-2

Recent Application in this class:
#301
20240034770
2024-02-01

T-CELL MODULATORY MULTIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF

#302
20240025956
2024-01-25

IL-2 MUTANT PROTEIN AND MEDICINE CONTAINING SAME

#303
20240010979
2024-01-11

MODIFIED NK-92 haNK003 CELLS FOR THE CLINIC

#304
20240010697
2024-01-11

MODIFIED INTERLEUKIN 2 (IL-2) POLYPEPTIDES, AND METHODS OF MAKING AND USING THE SAME

#305
20230416327
2023-12-28

IMMUNO ONCOLOGY THERAPIES WITH IL-2 CONJUGATES

#306
20230416326
2023-12-28

MODIFIED INTERLEUKIN-2 (IL-2) MOLECULE AND USE THEREOF

#307
20230416322
2023-12-28

TGF-Beta Polypeptides

#308
20230416308
2023-12-28

ENCAPSULATED RNA REPLICONS AND METHODS OF USE

#309
20230405150
2023-12-21

VIRAL VECTOR ENCODING GLP-1 RECEPTOR AGONIST FUSIONS AND USES THEREOF IN TREATING METABOLIC DISEASES IN FELINES

#310
20230399380
2023-12-14

Methods and Compositions for Treating Aging-Associated Impairments with TIMP-2 Recombinant Proteins

#311
20230399372
2023-12-14

T-cell modulatory multimeric polypeptides and methods of use thereof

#312
20230382999
2023-11-30

Artificial cell death polypeptide for chimeric antigen receptor and uses thereof

#313
20230382969
2023-11-30

INTERLEUKIN-2 PROPROTEINS AND USES THEREOF

#314
20230381278
2023-11-30

IL-2 ORTHOLOGS AND METHODS OF USE

#315
20230374102
2023-11-23

Methods for modulating an immune response

#316
20230374093
2023-11-23

ACTIVATABLE INTERLEUKIN-2 POLYPEPTIDES AND METHODS OF USE THEREOF

#317
20230365642
2023-11-16

BIFUNCTIONAL SUPERKINES AND USES THEREOF

#318
20230364186
2023-11-16

METHOD OF TREATING OR AMELIORATING A PATHOGENIC INFECTION BY ADMINISTERING AN INTERLEUKIN-2/TGF-BETA RECEPTOR FUSION POLYPEPTIDE

#319
20230364142
2023-11-16

COMPOSITION FOR ANTIVIRUS COMPRISING NATURAL KILLER CELL

#320
20230355804
2023-11-09

VIRUSES ENGINEERED TO PROMOTE THANOTRANSMISSION AND THEIR USE IN TREATING CANCER

#321
20230355691
2023-11-09

NOVEL RECOMBINANT VACCINIA VIRUS AND USE THEREOF

#322
20230348550
2023-11-02

IMMUNOSTIMULATING IL-2 ANALOGS

#323
20230348549
2023-11-02

CYTOKINE FUSION PROTEINS, AND THEIR PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS

#324
20230346900
2023-11-02

MHC class II T-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (T1D) and methods of use thereof

#325
20230340148
2023-10-26

METHOD FOR TREATING A GD2 POSITIVE CANCER

#326
20230340055
2023-10-26

GLYCOSYLATED IL-2 PROTEINS AND USES THEREOF

#327
20230340054
2023-10-26

INTERLEUKIN-2 MUTEINS AND USES THEREOF

#328
20230338473
2023-10-26

ANTAGONISTIC PEPTIDE TARGETING IL-2, IL-9, AND IL-15 SIGNALING FOR THE TREATMENT OF CYTOKINERELEASE SYNDROME AND CYTOKINE STORM ASSOCIATED DISORDERS

#329
20230331802
2023-10-19

METHOD TO PREPARE THERAPEUTICALLY ACTIVE ALDESLEUKIN HIGHLY STABLE IN LIQUID PHARMACEUTICAL COMPOSITIONS

#330
20230331801
2023-10-19

IL-2R-BETA-GAMMA BINDING COMPOUNDS

#331
20230331800
2023-10-19

IgG Fc-IL2-Rα-IL2 fusions and methods of use thereof

#332
20230322885
2023-10-12

COMPOSITIONS AND METHODS FOR SIMULTANEOUSLY MODULATING EXPRESSION OF GENES

#333
20230322884
2023-10-12

IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS AND RELATED DOSING

#334
20230322882
2023-10-12

Fusion Polypeptide and Polypeptide Dimer, and Use Thereof

#335
20230322881
2023-10-12

FUSION PROTEIN INCLUDING IL15 PROTEIN, IL15 RECEPTOR ALPHA PROTEIN, FC DOMAIN, AND IL2 PROTEIN, AND USE THEREOF

#336
20230321206
2023-10-12

MHC CLASS II T-CELL MODULATORY MULTIMERIC POLYPEPTIDES FOR TREATING TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF

#337
20230312720
2023-10-05

MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY

#338
20230312665
2023-10-05

NOVEL IL2 AGONISTS AND METHODS OF USE THEREOF

#339
20230310606
2023-10-05

CHIMERIC MYD88 RECEPTORS FOR REDIRECTING IMMUNOSUPPRESSIVE SIGNALING AND RELATED COMPOSITIONS AND METHODS

#340
20230303714
2023-09-28

Antibodies and methods for making and using the same

#341
20230303702
2023-09-28

COMBINATION THERAPY OF CANCER INVOLVING MULTI-SPECIFIC BINDING PROTEINS THAT BIND NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN

#342
20230303650
2023-09-28

Immunoconjugates of Interlukin-2 Mutant Polypeptides with Antibodies

#343
20230303649
2023-09-28

MODIFIED IL-2 POLYPEPTIDES FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES

#344
20230302132
2023-09-28

METHOD FOR PREPARING UNIVERSAL IMMUNE CELLS AND USE THEREOF

#345
20230302089
2023-09-28

CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES

#346
20230295287
2023-09-21

ANTI-VEGF ANTIBODY CONSTRUCTS AND RELATED METHODS FOR TREATING VESTIBULAR SCHWANNOMA ASSOCIATED SYMPTOMS

#347
20230295284
2023-09-21

ENHANCED-AFFINITY ANTI-ECM NANOBODY-CYTOKINE FUSIONS AND THEIR APPLICATIONS

#348
20230293685
2023-09-21

SELECTION OF IMPROVED TUMOR REACTIVE T-CELLS

#349
20230279424
2023-09-07

COMBINATION CYTOKINES FOR METHODS AND COMPOSITIONS FOR TREATING CANCER

#350
20230279076
2023-09-07

T-Cell Modulatory Polypeptides with Conjugation Sites and Methods of Use Thereof

#351
20230272066
2023-08-31

Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer, infections and autoimmune disorders

#352
20230272042
2023-08-31

FC-EPSILON CAR

#353
20230272028
2023-08-31

SEPARATION MOIETIES AND METHODS OF USE THEREOF

#354
20230270856
2023-08-31

FUSION PROTEIN AND USE THEREOF

#355
20230265150
2023-08-24

A FUSION PROTEON OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1) AND INTERLEUKIN-2 (IL-2) AND APPLICATIONS THEREOF

#356
20230265149
2023-08-24

ENCAPSULATED CELLS EXPRESSING IL-2 AND USES THEREOF

#357
20230265148
2023-08-24

IL-2 MUTANT AND APPLICATION THEREOF

#358
20230265147
2023-08-24

Interleukin-9 Signaling in Chimeric Antigen Receptor (CAR) Immune Cells

#359
20230257706
2023-08-17

T lymphocyte and use thereof

#360
20230257453
2023-08-17

COLLAGEN-TARGETED FUSION PROTEINS AND ANTIBODIES

#361
20230257439
2023-08-17

T-cell modulatory multimeric polypeptides and methods of use thereof

#362
20230257438
2023-08-17

FUSION PROTEIN COMPRISING ANTI-LAG-3 ANTIBODY AND IL-2, AND USE THEREOF

#363
20230256041
2023-08-17

Oncolytic Immunotherapy by Tumor Micro-Environment Remodeling

#364
20230250156
2023-08-10

MULTIMERS FOR VIRAL STRAIN EVOLUTION

#365
20230242663
2023-08-03

COMBINATION THERAPY COMPRISING ANTI-CD137 ANTIBODIES

#366
20230242607
2023-08-03

IL-2 VARIANTS

#367
20230235007
2023-07-27

HUMANIZED ACE2-FC FUSION PROTEIN FOR TREATMENT AND PREVENTION OF SARS-COV-2 INFECTION

#368
20230235006
2023-07-27

Masked IL-2-Fc fusion polypeptides

#369
20230235005
2023-07-27

Polypeptides Comprising Modified IL-2 Polypeptides and Uses Thereof

#370
20230235004
2023-07-27

TISSUE TARGETED IMMUNOTOLERANCE WITH PD-1 AGONISTS OR IL-2 MUTEINS

#371
20230233680
2023-07-27

PHARMACEUTICAL COMPOSITION FOR ENHANCING RADIOTHERAPY COMPRISING FUSION PROTEIN CONTAINING IL-2 PROTEIN AND CD80 PROTEIN

#372
20230227847
2023-07-20

VIRAL VECTORS EXPRESSING THERAPEUTIC PROTEINS SPECIFICALLY IN MYELOID CELLS AND MICROGLIA

#373
20230227575
2023-07-20

Engineered T Cells

#374
20230227562
2023-07-20

COMBINATION THERAPY OF CANCER INVOLVING MULTI-SPECIFIC BINDING PROTEINS THAT BIND NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN

#375
20230220032
2023-07-13

T-cell modulatory multimeric polypeptides and methods of use thereof

#376
20230212270
2023-07-06

SERUM ALBUMIN BINDING NANOBODY COMPOSITIONS AND METHODS FOR USING THE SAME

#377
20230210908
2023-07-06

METHODS FOR IMPROVED DELIVERY OF THERAPEUTIC AGENTS

#378
20230210897
2023-07-06

MODIFIED NATURAL KILLER CELLS AND METHODS OF USING THE SAME

#379
20230203119
2023-06-29

IMMUNOSTIMULATORY MULTIMERIC BINDING MOLECULES

#380
20230203118
2023-06-29

CYTOKINE COMBINATION

#381
20230201355
2023-06-29

Conjugate comprising an IL-2 moiety

#382
20230201335
2023-06-29

Antigen Presenting Polypeptide Complexes and Methods of Use Thereof

#383
20230201283
2023-06-29

RECOMBINANT VACCINIA VIRUS

#384
20230192859
2023-06-22

MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY

#385
20230183378
2023-06-15

MULTIMERS, TETRAMERS & OCTAMERS

#386
20230183331
2023-06-15

Modified TNF-α antibodies and uses thereof

#387
20230183307
2023-06-15

Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses

#388
20230174605
2023-06-08

IL-2 SEQUENCES AND USES THEREOF

#389
20230174604
2023-06-08

INTERLEUKIN-2 MUTANT AND USE THEREOF

#390
20230172982
2023-06-08

Elimination of BCMA-positive malignancies by CAR expressing NK cells

#391
20230159604
2023-05-25

PLASMID ENCODING B-CELL ACTIVATING FACTOR RECEPTOR (BAFF-R) AND USES OF SAME IN THE TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES IN FISH

#392
20230151113
2023-05-18

GPC3 CAR- T CELLS SECRETING IL-18 AND METHODS OF MAKING AND USING THE SAME

#393
20230151072
2023-05-18

MASKED IL-2 CYTOKINES AND THEIR CLEAVAGE PRODUCTS

#394
20230145766
2023-05-11

INTERLEUKIN-2 MUTANT AND USE THEREOF

#395
20230143831
2023-05-11

ANTIGEN-PRESENTING EXTRACELLULAR VESICLES, COMPOSITION CONTAINING SAME, AND METHOD FOR PRODUCTION THEREOF

#396
20230139890
2023-05-04

FUSION PROTEIN COMPRISING IL-2 PROTEIN AND CD80 PROTEIN FRAGMENT OR VARIANT THEREOF, AND USES THEREOF

#397
20230139534
2023-05-04

Methods of treating graft versus host disease using IL-2 muteins

#398
20230134606
2023-05-04

Immunoconjugates

#399
20230131917
2023-04-27

Modified T cells, pharmaceutical composition, manufacturing method thereof, and method of using the same

#400
20230126199
2023-04-27

IMMUNOREGULATORY METHOD, NUCLEIC ACID COMPOSITION FOR IMMUNOREGULATION AND USE THEREOF

#401
20230124171
2023-04-20

Immunostimulating IL-2 analogs

#402
20230117521
2023-04-20

T-CELL MODULATORY MULTIMERIC POLYPEPTIDES WITH CONJUGATION SITES AND METHODS OF USE THEREOF

#403
20230109980
2023-04-13

Methods for modulating an immune response

#404
20230108562
2023-04-06

NOVEL MASKED CYTOKINES AND METHODS OF USE THEREOF

#405
20230106973
2023-04-06

METHODS FOR EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES AND USE THEREOF

#406
20230104217
2023-04-06

FUSION PROTEIN COMPRISING IL-2 PROTEIN AND CD80 PROTEIN, AND USE THEREOF

#407
20230102344
2023-03-30

MULTIFUNCTIONAL MOLECULES THAT BIND TO CD33 AND USES THEREOF

#408
20230101046
2023-03-30

ANAPLASTIC LYMPHOMA KINASE CHIMERIC ANTIGEN RECEPTORS AND METHODS OF USE

#409
20230091105
2023-03-23

CHIMERIC FUSIONS BETWEEN C4-BINDING PROTEIN C-TERMINAL SEGMENT AND ANGIOPOIETIN-1 FIBRINOGEN-LIKE DOMAIN AS ANGIOPOIETIN MIMETICS AND TIE2 AGONISTS TO TREAT VASCULAR DISEASES

#410
20230080403
2023-03-16

IL-2 SUPERAGONISTS IN COMBINATION WITH ANTI-PD-1 ANTIBODIES

#411
20230079120
2023-03-16

INTERLEUKIN-2/INTERLEUKIN-2 RECEPTOR ALPHA FUSION PROTEINS AND METHODS OF USE

#412
20230071733
2023-03-09

Immunoconjugates

#413
20230069996
2023-03-09

LIGAND-BINDING FUSION PROTEINS

#414
20230064668
2023-03-02

Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof

#415
20230060637
2023-03-02

MODULATING GAMMA-C-CYTOKINE ACTIVITY

#416
20230057622
2023-02-23

Recombinant Human Neuregulin Derivatives and Use Thereof

#417
20230055644
2023-02-23

T-CELL MODULATORY CHIMERIC MOLECULES AND METHODS OF USE THEREOF

#418
20230053563
2023-02-23

NOVEL IL2 AGONISTS AND METHODS OF USE THEREOF

#419
20230051406
2023-02-16

GENETICALLY MODIFIED NATURAL KILLER CELLS AND METHODS OF USE THEREOF

#420
20230040604
2023-02-09

INTERLEUKIN-2 IN COMBINATION WITH TNF RECEPTOR FAMILY MEMBERS FOR THE EXPANSION OF T-REGULATORY CELLS

#421
20230036793
2023-02-02

INTERLEUKIN 2 CHIMERIC CONSTRUCTS

#422
20230030037
2023-02-02

Masked cytokine polypeptides

#423
20230028959
2023-01-26

Masked cytokine polypeptides

#424
20230027899
2023-01-26

CD122 WITH ALTERED ICD STAT SIGNALING

#425
20230023954
2023-01-26

Multi-functional and multi-valent interleukin-TGF-beta receptor fusion polypeptides

#426
20230002493
2023-01-05

PD-L1 TARGETED CHIMERIC PROTEINS AND USES THEREOF

#427
20230002467
2023-01-05

Superagonists, partial agonists and antagonists of interleukin-2

#428
20230002466
2023-01-05

ENGINEERED INTERLEUKIN-2 RECEPTOR BETA AGONISTS

#429
20230000918
2023-01-05

Chimeric antigen receptors, compositions and applications thereof

#430
20220403029
2022-12-22

ANTI-ICOS ANTIBODIES

#431
20220402989
2022-12-22

IL2-BASED THERAPEUTICS AND METHODS OF USE THEREOF

#432
20220401484
2022-12-22

Prame TCR Receptors And Uses Thereof

#433
20220389079
2022-12-08

MULTIMERIC T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF

#434
20220389070
2022-12-08

Fusion protein comprising IL-2 protein and CD80 protein, and use thereof

#435
20220380781
2022-12-01

Fusion protein comprising IL-2 protein and CD80 protein, and use thereof

#436
20220380487
2022-12-01

CHIMERIC CYTOKINE MODIFIED ANTIBODIES AND METHODS OF USE THEREOF

#437
20220380467
2022-12-01

ANTI-ICOS ANTIBODIES

#438
20220380428
2022-12-01

Dual cytokine fusion proteins comprising IL-10

#439
20220380427
2022-12-01

Dual cytokine fusion proteins comprising IL-10

#440
20220378827
2022-12-01

COMPOSITIONS AND METHODS FOR PROMOTING HEMATOPOIETIC CELL CYTOTOXICITY

#441
20220372098
2022-11-24

METHODS AND MATERIALS FOR TARGETED EXPANSION OF IMMUNE EFFECTOR CELLS

#442
20220372093
2022-11-24

TGF-β polypeptides

#443
20220363731
2022-11-17

INTERLEUKIN-2 DERIVATIVE

#444
20220362395
2022-11-17

IL2 agonists and methods of use thereof

#445
20220356224
2022-11-10

T-cell modulatory multimeric polypeptides and methods of use thereof

#446
20220356223
2022-11-10

IL2 Agonists

#447
20220354893
2022-11-10

BIOLOGICALLY RELEVANT ORTHOGONAL CYTOKINE/RECEPTOR PAIRS

#448
20220348930
2022-11-03

CAR NKTs Expressing Artificial Micro RNA-Embedded shRNA for Downregulation of MHC Class I & II Expression

#449
20220348625
2022-11-03

Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use

#450
20220340632
2022-10-27

T-cell modulatory multimeric polypeptides and methods of use thereof

#451
20220340631
2022-10-27

Dual cytokine fusion proteins comprising IL-10

#452
20220324987
2022-10-13

CD25 CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF

#453
20220324934
2022-10-13

DESIGNED IL-2 VARIANTS

#454
20220324933
2022-10-13

IL-2 COMPOSITIONS AND METHODS OF USE THEREOF

#455
20220324932
2022-10-13

MODIFIED IL-2 PROTEINS, PEG CONJUGATES, AND USES THEREOF

#456
20220323521
2022-10-13

Compositions and Uses for Engineered Therapeutic Microbes and Associated Receptors

#457
20220306716
2022-09-29

Masked interleukin-12 polypeptides

#458
20220306715
2022-09-29

CHIMERIC PROTEINS IN AUTOIMMUNITY

#459
20220306714
2022-09-29

IL-2 FUSION PROTEINS THAT PREFERENTIALLY BIND IL-2RALPHA

#460
20220289822
2022-09-15

NOVEL IL-21 PRODRUGS AND METHODS OF USE THEREOF

#461
20220289808
2022-09-15

T-cell modulatory multimeric polypeptides and methods of use thereof

#462
20220289807
2022-09-15

INTERLEUKIN-2 MUTEINS FOR THE EXPANSION OF T-REGULATORY CELLS

#463
20220289806
2022-09-15

Modified Interleukin 2 (IL-2) Polypeptides, Conjugates and Uses Thereof

#464
20220288200
2022-09-15

MULTISPECIFIC AND MULTIFUNCTIONAL MOLECULES AND USES THEREOF

#465
20220282216
2022-09-08

Primary NK CAR Constructs And Methods

#466
20220281942
2022-09-08

T CELL RECEPTORS AND METHODS OF USE THEREOF

#467
20220281935
2022-09-08

Dual cytokine fusion proteins comprising IL-10

#468
20220275040
2022-09-01

Dual cytokine fusion proteins comprising IL-10

#469
20220275039
2022-09-01

Dual cytokine fusion proteins comprising IL-10

#470
20220267400
2022-08-25

IL-2 CYTOKINE PRODRUGS COMPRISING A CLEAVABLE LINKER

#471
20220267399
2022-08-25

Fusion Protein And Composition For Treating Animal Tumors

#472
20220267397
2022-08-25

Dual cytokine fusion proteins comprising IL-10

#473
20220265854
2022-08-25

SYNTHETIC IMMUNE CELLS AND METHODS OF USE THEREOF

#474
20220265718
2022-08-25

IMMUNE CELLS EXPRESSING ENGINEERED ANTIGEN RECEPTORS

#475
20220265713
2022-08-25

SPHINGOLIPIDS FOR GENERATING REGULATORY CD4+ T CELLS

#476
20220257712
2022-08-18

Method of treating or ameliorating a pathogenic infection by administering an interleukin-2/TGF-β receptor fusion polypeptide

#477
20220251202
2022-08-11

FUSIONS OF MUTANT INTERLEUKIN-2 POLYPEPTIDES WITH ANTIGEN BINDING MOLECULES FOR MODULATING IMMUNE CELL FUNCTION

#478
20220251161
2022-08-11

Agents and Methods for Treating Viral Infections

#479
20220251160
2022-08-11

IN VIVO TARGETING OF CELLS WITH LIGAND-CONJUGATED PARTICLES

#480
20220242971
2022-08-04

NOVEL IMMUNOCONJUGATES

#481
20220242946
2022-08-04

METHODS AND MATERIALS FOR TARGETED EXPANSION OF REGULATORY T CELLS

#482
20220235133
2022-07-28

MONOCLONAL ANTIBODY-CYTOKINE FUSION PROTEIN DIMER AND APPLICATION THEREOF

#483
20220235110
2022-07-28

De novo design of potent and selective interleukin mimetics

#484
20220235109
2022-07-28

NOVEL INTERLEUKIN-2 VARIANTS FOR THE TREATMENT OF CANCER

#485
20220233590
2022-07-28

CD19-DIRECTED CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF IN IMMUNOTHERAPY

#486
20220229070
2022-07-21

METHOD OF DIAGNOSING CANCER AND DIAGNOSIS KIT USING MEASUREMENT OF NK CELL ACTIVITY

#487
20220227837
2022-07-21

IL-2 COMPOSITIONS AND METHODS OF USE THEREOF

#488
20220227829
2022-07-21

IL-2 MUTANT PROTEIN PROLIFERATING IMMUNE CELLS

#489
20220220182
2022-07-14

IL2 agonists and methods of use thereof

#490
20220220181
2022-07-14

Separation moieties and methods of use thereof

#491
20220220180
2022-07-14

NOVEL METHOD

#492
20220213163
2022-07-07

IL-2 CHIMERIC PROTEINS FOR IMMUNOSUPPRESSION

#493
20220213162
2022-07-07

Engineered IL-2 Fc fusion proteins

#494
20220213160
2022-07-07

PROTEIN HETERODIMER AND USE THEREOF

#495
20220211803
2022-07-07

PROTEIN MOLECULE AND USE THEREOF

#496
20220204579
2022-06-30

METHODS OF PRODUCING AGGREGATE-FREE MONOMERIC DIPHTHERIA TOXIN FUSION PROTEINS AND THERAPEUTIC USES

#497
20220204578
2022-06-30

Superagonists and antagonists of interleukin-2

#498
20220195003
2022-06-23

IL-2 muteins and uses thereof

#499
20220193197
2022-06-23

SYNERGISTIC TUMOR TREATMENT WITH IL-2 AND INTEGRIN-BINDING-FC FUSION PROTEIN

#500
20220185860
2022-06-16

CELL SURFACE COUPLING OF NANOPARTICLES

#501
20220185859
2022-06-16

IL-2 muteins and uses thereof

#502
20220177592
2022-06-09

Artificial cell death polypeptide for chimeric antigen receptor and uses thereof

#503
20220177544
2022-06-09

Interleukin-2 receptor (IL2R) and interleukin-2 (IL2) variants for specific activation of immune effector cells

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20220177536
2022-06-09

T-cell modulatory multimeric polypeptides and methods of use thereof

#505
20220177535
2022-06-09

Methods of using interleukin-2 agents

#506
20220170028
2022-06-02

NOVEL INTERLEUKIN-2 VARIANTS AND BIFUNCTIONAL FUSION MOLECULES THEREOF

#507
20220144952
2022-05-12

Anti-B7-H4 chimeric antigen receptor-modified NK-92 cells

#508
20220143092
2022-05-12

Methods and compositions for natural killer cells

#509
20220143088
2022-05-12

CYTOKINE-BASED IMMUNE CELLS AND IMMUNOTHERAPEUTIC USE THEREOF

#510
20220143063
2022-05-12

T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF

#511
20220135645
2022-05-05

Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof

#512
20220127639
2022-04-28

NON-HLA MATCHED HUMANIZED NSG MOUSE MODEL WITH PATIENT-DERIVED XENOGRAFT

#513
20220127638
2022-04-28

NON-HLA MATCHED HUMANIZED NSG MOUSE MODEL WITH PATIENT-DERIVED XENOGRAFT

#514
20220127368
2022-04-28

BISPECIFIC IMMUNOTOXINS TARGETING HUMAN CD25+CCR4+ TUMORS AND REGULATORY T-CELLS

#515
20220127332
2022-04-28

Multi-functional and multi-valent interleukin-TGF-beta receptor fusion polypeptides

#516
20220125884
2022-04-28

Interleukin-2 variant proteins fused to human IgG4 Fc and uses thereof

#517
20220125836
2022-04-28

TREATMENT INVOLVING CAR-ENGINEERED T CELLS AND CYTOKINES

#518
20220119824
2022-04-21

IMMUNOSTIMULATORY BACTERIA-BASED VACCINES, THERAPEUTICS, AND RNA DELIVERY PLATFORMS

#519
20220118013
2022-04-21

METHODS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND USES THEREOF

#520
20220112260
2022-04-14

MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES

#521
20220112252
2022-04-14

MULTIMERIC T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF

#522
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2022-03-31

CHEMOKINE EXPRESSING CELL AND USE THEREOF

#523
20220089750
2022-03-24

CAR-EXPRESSING CELLS AGAINST MULTIPLE TUMOR ANTIGENS AND USES THEREOF

#524
20220089681
2022-03-24

Methods for modulating an immune response

#525
20220089680
2022-03-24

MULTIMERIC T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF

#526
20220089667
2022-03-24

Polypeptides Comprising Modified IL-2 Polypeptides and Uses Thereof

#527
20220073581
2022-03-10

Antibodies comprising a polypeptide inserted in framework 3 region

#528
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2022-03-03

T-CELL MODULATORY MULTIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF

#529
20220056475
2022-02-24

Recombinant poxviruses for cancer immunotherapy

#530
20220056096
2022-02-24

Activatable interleukin-2 polypeptides and methods of use thereof

#531
20220056095
2022-02-24

De novo design of potent and selective interleukin mimetics

#532
20220056094
2022-02-24

HUMAN INTERLEUKIN-2 VARIANT OR DERIVATIVE THEREOF

#533
20220056093
2022-02-24

Interleukin-2 polypeptide conjugates and their uses

#534
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2022-02-17

SALMONELLA VACCINE FOR THE TREATMENT OF CORONAVIRUS

#535
20220040232
2022-02-10

MATERIALS AND METHODS FOR PRODUCING BIOENGINEERED VIRUS SPECIFIC LYMPHOCYTES

#536
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2022-02-03

RECOMBINANT VACCINIA VIRUS

#537
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2022-02-03

METHODS FOR EX VIVO EXPANSION OF NATURAL KILLER CELLS AND USE THEREOF

#538
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2022-02-03

T-cell modulatory multimeric polypeptides and methods of use thereof

#539
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2022-01-27

CHIMERIC ANTIGEN RECEPTOR-MODIFIED NK-92 CELLS TARGETING EGFR SUPER-FAMILY RECEPTORS

#540
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2022-01-27

NOVEL IMMUNOSUPPRESSIVE INTERLEUKIN 2

#541
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2022-01-27

Fusion proteins with extended serum half life

#542
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2022-01-20

Split interleukin mimetics and their use

#543
20220017587
2022-01-20

Dual cytokine fusion proteins comprising IL-10

#544
20220017586
2022-01-20

EXPOSED COLLAGEN-TARGETED FUSION CYTOKINE FOR IMMUNE MODULATION IN INVASIVE CANCERS AND LESIONS OF INFECTIONS

#545
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2022-01-06

MASKED CYTOKINE POLYPEPTIDES

#546
20210403579
2021-12-30

MULTIVALENT REGULATORY T CELL MODULATORS

#547
20210403524
2021-12-30

Activatable interleukin-2 polypeptides and methods of use thereof

#548
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2021-12-23

THERAPEUTIC COMPOUNDS AND METHODS

#549
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2021-12-23

IL-2 FUSION POLYPEPTIDE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME

#550
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2021-12-23

Protein heterodimer and use thereof

#551
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2021-12-16

SPHINGOSINE KINASE 1 AND FUSION PROTEIN COMPRISING THE SAME AND USE THEREOF

#552
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2021-12-16

Circular tandem repeat proteins

#553
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2021-12-16

Novel Rationally Designed Protein Compositions

#554
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2021-12-16

QUADRICISTRONIC SYSTEM COMPRISING A HOMING RECEPTOR AND CHIMERIC ANTIGEN RECEPTOR FOR STABLE GENETIC MODIFICATION OF CELLULAR IMMUNOTHERAPIES

#555
20210380943
2021-12-09

GENERATING HPV ANTIGEN-SPECIFIC T CELLS FROM A NAÏVE T CELL POPULATION

#556
20210380699
2021-12-09

Anti-PD-L1 antibodies

#557
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2021-12-02

IL-2 FUSION POLYPEPTIDE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME

#558
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2021-11-11

Fc-epsilon car

#559
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2021-11-11

DECOY POLYPEPTIDES

#560
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2021-11-04

Conjugates of an IL-2 moiety and a polymer

#561
20210340209
2021-11-04

Activatable IL2 composition and methods of use

#562
20210340208
2021-11-04

Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications

#563
20210340207
2021-11-04

Human interleukin-2 conjugates biased for the interleukin-2 receptor beta GAMMAc dimer and conjugated to a nonpeptidic, water-soluble polymer

#564
20210324030
2021-10-21

IL-2 variants with reduced binding to IL-2 receptor alpha and uses thereof

#565
20210324029
2021-10-21

STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY

#566
20210324028
2021-10-21

IL-15 Variants and Uses Thereof

#567
20210322477
2021-10-21

ELIMINATION OF PD-L1-POSITIVE MALIGNANCIES BY PD-L1 CHIMERIC ANTIGEN RECEPTOR-EXPRESSING NK CELLS

#568
20210317185
2021-10-14

Modular synthetic receptors and methods of use

#569
20210317183
2021-10-14

Enhanced antigen presenting ability of RNA car T cells by co-introduction of costimulatory molecules

#570
20210315934
2021-10-14

ELIMINATION OF PD-L1-POSITIVE MALIGNANCIES BY PD-L1 CHIMERIC ANTIGEN RECEPTOR-EXPRESSING NK CELLS

#571
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2021-10-07

IL-2 VARIANTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES

#572
20210308186
2021-10-07

Treatment of Acute Respiratory Distress Syndrome by T Regulatory Cells

#573
20210299222
2021-09-30

THERAPEUTICALLY ACTIVE ALDESLEUKIN HIGHLY STABLE IN LIQUID PHARMACEUTICAL COMPOSITIONS

#574
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2021-09-23

Immunotherapeutic tumor treatment method

#575
20210292386
2021-09-23

IL2 Agonists

#576
20210284754
2021-09-16

HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFICATIONS

#577
20210284706
2021-09-16

Compositions and methods for targeted cytokine delivery

#578
20210277355
2021-09-09

GENERATING VIRUS OR OTHER ANTIGEN-SPECIFIC T CELLS FROM A NAÏVE T CELL POPULATION

#579
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2021-09-09

TARGETED IMMUNOTOLERANCE

#580
20210275588
2021-09-09

Biomolecule Coated Particles and Films and Uses Thereof

#581
20210269500
2021-09-02

Cell surface coupling of nanoparticles

#582
20210269498
2021-09-02

Partial agonists of interleukin-2

#583
20210269497
2021-09-02

INTERLEUKIN-2 VARIANTS AND METHODS OF USES THEREOF

#584
20210269496
2021-09-02

Tissue targeted immunotolerance with a CD39 effector

#585
20210261640
2021-08-26

Compositions and methods for treatment of autoimmune and inflammatory diseases and disorders

#586
20210260163
2021-08-26

NOVEL CYTOKINE PRODRUGS

#587
20210253671
2021-08-19

Pharmaceutical Composition Containing Fusion Protein and Use Thereof

#588
20210252059
2021-08-19

Engineered safety in cell therapy

#589
20210246200
2021-08-12

Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof

#590
20210246184
2021-08-12

Method to prepare therapeutically active aldesleukin highly stable in liquid pharmaceutical compositions

#591
20210246183
2021-08-12

Interleukin-2 fusion proteins and uses thereof

#592
20210238558
2021-08-05

USES AND METHODS FOR ONCOLYTIC VIRUS TARGETING OF IL-4/IL-13 AND FUSIONS THEREOF

#593
20210238246
2021-08-05

Fusion proteins composed of an interleukin-2 mutein and type I interferon

#594
20210230547
2021-07-29

Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors

#595
20210230269
2021-07-29

IMMUNE-STIMULATING MONOCLONAL ANTIBODIES AGAINST HUMAN INTERLEUKIN-2

#596
20210221864
2021-07-22

MASKED CYTOKINE CONJUGATES

#597
20210221863
2021-07-22

Interleukin-2 and use thereof

#598
20210220486
2021-07-22

Immunostimulating vector system

#599
20210214428
2021-07-15

IMMUNE CHECKPOINT THERAPY

#600
20210214410
2021-07-15

IL-13/IL-4 SUPERKINES: IMMUNE CELL TARGETING CONSTRUCTS AND METHODS OF USE THEREOF