96976 ⎘
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans; Cytokines; Lymphokines; Interferons; Interleukins [IL] IL-2
NOVEL INTERLEUKIN-2 AND USE THEREOF
#602Methods for modulating an immune response
#603FC-EPSILON CAR (Very imp commercially - in clinical trial)
#604T-cell modulatory multimeric polypeptides and methods of use thereof
#605IL-2R-βγ binding compounds
#606IL-2 orthologs and methods of use
#607RECOMBINANT MYXOMA VIRUSES AND USES THEREOF
#608NOVEL IL2 AGONISTS AND METHODS OF USE THEREOF
#609IL2 and peptide-MHC complex fusion proteins and methods of use thereof
#610SUBSETS OF HUMAN NATURAL KILLER CELLS WITH ENHANCED ANTIBODY-DIRECTED IMMUNE RESPONSES
#611NUCLEIC ACID APTAMERS
#612IMMUNOREACTANT CARRIER
#613SINGLE CHAIN Fc FUSION PROTEINS
#614Generating HPV antigen-specific cells from a naive T cell population
#615Cytokine fusion proteins, and their pharmaceutical compositions and therapeutic applications
#616Generating HPV antigen-specific cells from a naive T cell population
#617METHOD FOR PREPARING INTERLEUKIN-2 OR INTERLEUKIN-2 ANALOGUES
#618Viral vectors and packaging cell lines
#619Interleukin-2 muteins for the expansion of T-regulatory cells
#620Cytokine-based bioactivatable drugs and methods of uses thereof
#621RECOMBINANT ONCOLYTIC VIRUS COMPOSITION AND USE THEREOF
#622Immunotherapeutic tumor treatment method
#623SEPARATION MOIETIES AND METHODS OF USE THEREOF
#624TARGETING STAT SUMOYLATION TO ENHANCE IMMUNE RESPONSES
#625TREATMENT USING CYTOKINE ENCODING RNA
#626T-cell modulatory multimeric polypeptides and methods of use thereof
#627Human Interleukin-2 and Anti-human Epithelial Cell Adhesion Molecule Single-Chain Antibody Fusion Protein and Application Thereof
#628Methods for treating vascular leak syndrome and cancer
#629Interleukin-2 muteins for the expansion of T-regulatory cells
#630Targeted immunotolerance
#631METHODS AND COMPOSITIONS FOR TREATING CANCER WITH ECM-AFFINITY PEPTIDES LINKED TO CYTOKINES
#632COMBINATION THERAPY OF CANCER INVOLVING MULTI-SPECIFIC BINDING PROTEINS THAT ACTIVATE NATURAL KILLER CELLS
#633Superagonists, partial agonists and antagonists of interleukin-2
#634Immune cells engineered to express CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
#635CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
#636MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
#637Il-2 conjugates and methods of use to treat autoimmune diseases
#638Biologically relevant orthogonal cytokine/receptor pairs
#639METHOD AND SYSTEM FOR SCREENING ANTI-TUMOUR SUBSTANCES
#640HIGH AFFINITY NY-ESO T CELL RECEPTORS
#641Cancer immunotherapy using CD19-directed chimeric antigen receptors
#642BIOLOGICALLY RELEVANT ORTHOGONAL CYTOKINE/RECEPTOR PAIRS
#643Antibodies to tumour antigens
#644Anti-CD25 antibody agents
#645Cytokine fusion proteins
#646MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
#647COMBINATION THERAPY USING A CHIMERIC ANTIGEN RECEPTOR
#648Compositions and methods for targeted cytokine delivery
#649BI-FUNCTIONAL PROTEINS AND CONSTRUCTION THEREOF
#650IL-2 Conjugates
#651Interleukin-2 agents and uses thereof
#652CONJUGATES OF AN IL-2 MOIETY AND A POLYMER
#653Chimeric transmembrane proteins and uses thereof
#654Anti-CD25 for tumour specific cell depletion
#655Anti-CD25 for tumour specific cell depletion
#656Anti-CD25 for tumour specific cell depletion
#657Anti-CD25 antibody agents
#658Masked cytokine polypeptides
#659Anti-CD25 antibody agents
#660Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof
#661Enhanced adoptive cell therapy
#662METHODS OF PRODUCING MODIFIED NATURAL KILLER CELLS AND METHODS OF USE
#663METHODS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND USES THEREOF
#664Method for NK cell transduction
#665Engineered proteins to enhance sensitivity of a cell to IL-2
#666ELIMINATION OF CD19-POSITIVE LYMPHOID MALIGNANCIES BY CD19-CAR EXPRESSING NK CELLS
#667Fusion protein comprising IL-2 protein and CD80 protein, and use thereof
#668APPLICATIONS OF SOLUBLE PROTEIN BAFF IN B CELL IN-VITRO CULTURE AND PROLIFERATION
#669Modified NK-92 haNK003 cells for the clinic
#670De novo design of potent and selective interleukin mimetics
#671Method of treating glioblastoma multiforme
#672De novo design of potent and selective interleukin mimetics
#673MODULATION OF T CELLS WITH BISPECIFIC ANTIBODIES AND FC FUSIONS
#674Methods for modulating an immune response
#675Expression of metabolic modulators in tumor microenvironment to improve tumor therapy
#676Methods for modulating an immune response
#677IL-2 muteins and uses thereof
#678IL-2 muteins and uses thereof
#679De novo design of potent and selective interleukin mimetics
#680Tethered interleukin-2 to its receptor IL-2RBETA, a platform to enhance natural killer and regulatory T cell activity
#681PARTIAL AGONISTS OF INTERLEUKIN-2
#682Compositions and methods for immunomodulation in an organism
#683T CELL RECEPTOR FUSIONS AND CONJUGATES AND METHODS OF USE THEREOF
#684Activatable interleukin-2 polypeptides and methods of use thereof
#685Antibody-IL2 engrafted proteins and methods of use in the treatment of cancer
#686SIRP-gamma polypeptide compositions and treatment of cancer
#687NOVEL INTERLEUKIN 4 IMMUNOCONJUGATES
#688METHODS, COMPOSITIONS, AND IMPLANTABLE ELEMENTS COMPRISING ACTIVE CELLS
#689Cytokine conjugates for the treatment of autoimmune diseases
#690T-CELL MODULATORY MULTIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF
#691Cytokine combination
#692T-cell modulatory multimeric polypeptides and methods of use thereof
#693Circular tandem repeat proteins
#694Cytokine conjugates for the treatment of proliferative and infectious diseases
#695aNK AND IL-12 COMPOSITIONS AND METHODS
#696CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES
#697T CELL RECEPTOR FUSIONS AND CONJUGATES AND METHODS OF USE THEREOF
#698Interleukin-2 fusion proteins and uses thereof
#699Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses
#700Therapeutic compounds and methods
#701Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders
#702USE OF IL-12 TO GENERATE ENDOGENOUS ERYTHROPOIETIN
#703Elimination of CD19-positive lymphoid malignancies by CD19-CAR expressing NK cells
#704Elimination of PD-L1-positive malignancies by PD-L1 chimeric antigen receptor-expressing NK cells
#705Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases
#706Quadricistronic system comprising a homing receptor and chimeric antigen receptor for stable genetic modification of cellular immunotherapies
#707Kinase mutants and uses thereof
#708Quadricistronic system comprising a homing receptor and chimeric antigen receptor for stable genetic modification of cellular immunotherapies
#709THERAPEUTIC COMPOUNDS AND METHODS
#710Immune cells expressing engineered antigen receptors
#711Method for Treating a GD2 Positive Cancer
#712Antibodies and methods for making and using the same
#713Fusion protein for restoring the functions of failing immune cells and application thereof
#714Ligands Modified by Circular Permutation as Agonists and Antagonists
#715Activatable interleukin-2 polypeptides
#716Quadricistronic system comprising a homing receptor and chimeric antigen receptor for stable genetic modification of cellular immunotherapies
#717Multivalent regulatory T cell modulators
#718Compositions comprising R-Spondin (RSPO) surrogate molecules
#719Interleukin-2 muteins for the expansion of T-regulatory cells
#720Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody
#721Combination of an anti-CD16A antibody with a cytokine
#722METHODS FOR MODULATING AN IMMUNE RESPONSE
#723MULTI-SITE SPECIFIC INTEGRATION CELLS FOR DIFFICULT TO EXPRESS PROTEINS
#724De novo design of potent and selective interleukin mimetics
#725MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
#726COMBINATION THERAPY OF TUMOR-TARGETED IL-2 VARIANT IMMUNOCYTOKINES AND ANTIBODIES AGAINST HUMAN PD-L1
#727Materials and methods relating to dosage regimen design
#728Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use
#729Antibody binding PD-1 and use thereof
#730IMMUNE CHECKPOINT THERAPY
#731T-CELL MODULATORY MULTIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF
#732METHODS OF TREATING MULTIPLE SCLEROSIS USING AUTOLOGOUS T CELLS
#733RP215 chimeric antigen receptor construct and methods of making and using same
#734Synergistic tumor treatment with an extended pharmacokinetic IL-2 and integrin-binding-Fc fusion protein
#735Anti-PD-L1 and IL-2 cytokines
#736ANTI-PD-L1 ANTIBODIES
#737Anti-ICOS antibodies
#738MUTANT INTERLEUKIN-2 POLYPEPTIDES
#739NOVEL IMMUNOCONJUGATES
#740Anti-CD25 antibody agents
#741Immunoconjugates
#742Method for increasing the secretion levels of interleukin 2 and muteins thereof by introducing a point mutation
#743Modified NK-92 haNK003 cells for the clinic
#744Anti-CD25 antibody agents
#745Interleukin-2/Interleukin-2 receptor alpha fusion proteins and methods of use
#746Anti-CD25 antibody agents
#747IL2 and TNF immunoconjugates
#748CHEMOKINE-CYTOKINE FUSION PROTEINS AND THEIR APPLICATIONS
#749CYSTEINE VARIANTS OF INTERLEUKIN-11 AND METHODS OF USE THEREOF
#750SOLUBLE TCR MOLECULES AND METHODS OF USE
#751Modified natural killer cells for the treatment of cancer
#752IL-15 variants and uses thereof
#753ARTIFICIAL ANTIGEN PRESENTING CELLS FOR EXPANDING IMMUNE CELLS FOR IMMUNOTHERAPY
#754Fusion proteins with extended serum half life
#755Superagonists and antagonists of interleukin-2
#756Engineered IL-2 Fc fusion proteins
#757Multimers, tetramers and octamers
#758MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY
#759Nucleic acid encoding human IL-2 variant
#760Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases
#761GENE THERAPY VECTORS AND CYTOSINE DEAMINASES
#762Biologically relevant orthogonal cytokine/receptor pairs
#763Methods for treating vascular leak syndrome and cancer
#764Methods for expanding and activating γδ T cells for the treatment of cancer and related malignancies
#765IL-2 MUTEINS AND USES THEREOF
#766IL-2 MUTEINS AND USES THEREOF
#767Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells
#768Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases
#769Nucleic acid aptamers
#770COMPOSITIONS AND METHODS FOR IMPROVED NK CELL THERAPIES
#771Non-glycosylated anti-tenascin antibody
#772Method of treating graft versus host disease with an interleukin-2 mutein
#773Compositions and methods for targeted cytokine delivery
#774Compositions and methods for targeted cytokine delivery
#775Mutant interleukin-2 polypeptides
#776Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses
#777Modulating gamma-c-cytokine activity
#778IL-2 superagonists in combination with anti-PD-1 antibodies
#779METHODS FOR THE DIAGNOSTIC OF AN AUTOIMMUNE DISEASE
#780Immunostimulating vector system
#781METHOD FOR PREPARING INTERLEUKIN-2 OR INTERLEUKIN-2 ANALOGUES
#782Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof
#783COMBINATION THERAPY COMPRISING A SUPERAGONISTIC ANTIBODY AGAINST INTERLEUKIN-2 AND A CHECKPOINT BLOCKADE AGENT
#784Method of refolding an interleukin-2 (IL-2) protein
#785COMPOSITIONS AND METHODS FOR REGULATABLE ANTIBODY EXPRESSION
#786Circular tandem repeat proteins
#787Drug Design Method, Obtained Drug and Application Thereof
#788HIGH AFFINITY NY-ESO T CELL RECEPTORS
#789High affinity T cell receptors and uses thereof
#790Targeted immunotolerance
#791Variant serum albumin with improved half-life and other properties
#792Immunoconjugates
#793Interleukin-2 muteins for the expansion of T-regulatory cells
#794Generating HPV antigen-specific cells from a naive T cell population
#795Compositions and methods for immunomodulation in an organism
#796SECRETORY TNT CAR CELL IMMUNOTHERAPY
#797Single chain Fc fusion proteins
#798Therapeutic compounds and methods
#799Modified NK-92 haNK003 cells for the clinic
#800Interleukin-2 muteins for the expansion of T-regulatory cells
#801Method for producing interleukin-2 protein using methylotrophic yeast
#802Biologically relevant orthogonal cytokine/receptor pairs
#803Exposed collagen-targeted fusion cytokine for immune modulation in invasive cancers and lesions of infections
#804COMBINATION THERAPY OF TUMOR-TARGETED IL-2 VARIANT IMMUNOCYTOKINES AND ANTIBODIES AGAINST HUMAN PD-L1
#805Non-HLA matched humanized NSG mouse model with patient-derived xenograft
#806Multivalent regulatory T cell modulators
#807SIRP-gamma polypeptide compositions and methods of use
#808Mutant interleukin-2 polypeptides
#809Method for treating a GD2 positive cancer
#810IL-2 variants for the treatment of psoriasis
#811T CELL RECEPTOR FUSIONS AND CONJUGATES AND METHODS OF USE THEREOF
#812Conjugates of an IL-2 moiety and a polymer
#813IL2 and TNF immunoconjugates
#814GENERATING VIRUS OR OTHER ANTIGEN-SPECIFIC T CELLS FROM A NAÏVE T CELL POPULATION
#815HIGH AFFINITY NY-ESO T CELL RECEPTORS
#816Anti-ICOS antibodies
#817Car-expressing cells against multiple tumor antigens and uses thereof
#818Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases
#819METHOD FOR TREATING A TUMOR WITH BIFUNCTIONAL AGENTS THAT BIND TO TUMOR CARBOHYDRATE ANTIGENS
#820Interleukin-2 expression construct using human serium albumin
#821Methods for treating inflammation with fusion proteins comprising interleukin-2 and interleukin-33
#822Methods for treating vascular leak syndrome and cancer
#823Interleukin-2 fusion proteins and uses thereof
#824Method to increase the number of circulating platelets by administering PEGylated cysteine variants of IL-11
#825Multispecific and multifunctional molecules and uses thereof
#826Method of treating cancer with a multiple integrin binding Fc fusion protein
#827Antibodies and immunocytokines
#828Methods and compositions relating to improved lentiviral vectors and their applications
#829Methods and compositions for natural killer cells
#830MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
#831Chemokine-cytokine fusion proteins of SDF-1 and CD40L
#832Cytokine-based fusion proteins for treatment of immune disorders
#833Method of promoting regulatory T-cell proliferation
#834Nucleic acid constructs for presentation of CD4 and CD8 epitopes, cellular transfection and uses thereof
#835Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use
#836Tumor infiltrating cells engineered to express a pro-inflammatory polypeptide
#837Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 or CTLA4 and integrin-binding-Fc-fusion protein
#838MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
#839Immune-stimulating monoclonal antibodies against human interleukin-2
#840Enhanced adoptive cell therapy
#841Interleukin-2 muteins for the expansion of T-regulatory cells
#842ALBUMIN FUSION PROTEINS
#843Immunoconjugates
#844High affinity NY-ESO T cell receptors
#845Interleukin-2 muteins for the expansion of T-regulatory cells
#846Cell surface coupling of nanoparticles
#847Compositions of GM-CSF and interleukin fusions for immune modulation and uses related thereto
#848METHODS AND COMPOSITIONS RELATING TO RESTRICTED EXPRESSION LENTIVIRAL VECTORS AND THEIR APPLICATIONS
#849MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
#850IL-2 peptide derivatives, and uses thereof for the diagnosis and treatment of an autoimmune disease
#851Superagonists, partial agonists and antagonists of interleukin-2
#852Ligands modified by circular permutation as agonists and antagonists
#853MOLECULES THAT SELECTIVELY ACTIVATE REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
#854Superagonists and antagonists of interleukin-2
#855MESENCHYMAL STEM CELLS FOR TARGETED CANCER THERAPY
#856Methods and compositions relating to improved lentiviral vectors and their applications
#857IN VIVO TARGETING OF CELLS WITH LIGAND-CONJUGATED PARTICLES
#858Compositions and methods for immunomodulation in an organism
#859Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
#860SIRP polypeptide compositions and methods of use
#861Compositions and methods for immunomodulation in an organism
#862Fusion protein comprising interleukin-2 and interleukin-33
#863Boosting Treg cells for treating Alzheimer disease and related disorders
#864Immunoconjugates
#865Fusion polypeptides comprising mucin-domain polypeptide linkers
#866Interleukin-2 fusion proteins and uses thereof
#867Mutant interleukin-2 polypeptides
#868SINGLE CHAIN FC FUSION PROTEINS
#869ALBUMIN FUSION PROTEINS
#870POLYMER PARTICLES AND USES THEREOF
#871INTERLEUKIN-2 FUSION PROTEINS AND USES THEREOF
#872Methods and compositions relating to improved lentiviral vectors and their applications
#873Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
#874Methods of treating a neoplastic disease
#875Bivalent IL-2 fusion toxins
#876Modified toxins
#877Albumin fusion proteins
#878CHEMOKINE-CYTOKINE FUSION PROTEINS AND THEIR APPLICATIONS
#879Enhanced adoptive cell therapy
#880METHOD AND SYSTEM TO REMOVE SOLUBLE TNFR1, TNFR2, AND IL2 IN PATIENTS
#881Interleukin-2 fusion proteins and uses thereof
#882Albumin fusion proteins
#883Compositions and methods for immunomodulation in an organism
#884Cytokine-based fusion proteins for treatment of immune disorders
#885Compositions and methods for Immunomodulation in an organism
#886Alteration of cell membrane for new functions using IL-2 and streptavidin
#887T CELL RECEPTOR FUSIONS AND CONJUGATES AND METHODS OF USE THEREOF
#888Compositions, methods and kits for treatment of cancer and autoimmune diseases
#889SYNERGISTIC TUMOR TREATMENT WITH EXTENDED-PK IL-2 AND ADOPTIVE CELL THERAPY
#890Modified SAK gene for the production of recombinant proteins
#891Soluble TCR molecules and methods of use
#892Aglycosylated Fc-containing polypeptides with cysteine substitutions
#893Conjugates of an IL-2 moiety and a polymer
#894VARIANT SERUM ALBUMIN WITH IMPROVED HALF-LIFE AND OTHER PROPERTIES
#895IL-2 derivative polypeptides
#896Targeting regulatory T cells with heterodimeric proteins
#897Light chain immunoglobulin fusion proteins and methods of use thereof
#898Combination of an anti-EDb fibronectin antibody-IL-2 fusion protein, and a molecule binding to B cells, B cell progenitors and/or their cancerous counterpart
#899Interleukin-2 muteins for the expansion of T-regulatory cells
#900Compositions comprising TL1A-Ig fusion protein for the regulation of T regulatory cells, and methods for their use