97337 ⎘
Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF
#1202Therapeutic agents
#1203Compositions and methods for inhibition of lineage specific antigens
#1204Nucleic acid molecules encoding chimeric antigen receptors targeting B-cell maturation antigen and uses thereof
#1205Methods of using chimeric antigen receptors targeting B-cell maturation antigen and uses thereof
#1206Chimeric cytokine receptors bearing a PD-1 ectodomain
#1207ARTICLES AND METHODS DIRECTED TO PERSONALIZED THERAPY OF CANCER
#1208Tumor specific antibodies and T-cell receptors and methods of identifying the same
#1209Compositions and methods for improved T cells
#1210Coiled coil immunoglobulin fusion proteins and compositions thereof
#1211GAMMA DELTA T CELLS AND USES THEREOF
#1212COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY
#1213CD33 exon 2 deficient donor stem cells for use with CD33 targeting agents
#1214Universal platform for preparing an inhibitory chimeric antigen receptor (iCAR)
#1215Engineered clostridium botulinum toxin adapted to deliver molecules into selected cells
#1216Compositions and methods for treatment of cancer
#1217Tagged chimeric effector molecules and receptors thereof
#1218Cells Expressing Cell Surface Receptors and Antibodies
#1219Chimeric Antigen Receptor
#1220Fusion proteins having a toxin and cancer marker, nanoparticles, and uses related thereto
#1221Methods of treating cancer by administering antigen-binding molecules comprising a TNF family ligand trimer
#1222Anti-IL1RAP antibodies
#1223pHLIP® peptide-mediated epitope tethering at cell surfaces
#1224Homodimeric protein constructs
#1225Engineered microbe-targeting molecules and uses thereof
#1226Conjugated knottin mini-proteins containing non-natural amino acids
#1227NANOSTRUCTURED PROTEINS AND USES THEREOF
#1228VACCINES FOR TREATMENT AND PREVENTION OF CANCER
#1229Methods for treating pseudoxanthoma elasticum (PXE)
#1230Chimeric antigen receptor and methods of use thereof
#1231Targeted gene integration of NK inhibitors genes for improved immune cells therapy
#1232T-cells expressing anti-LIV1 chimeric antigen receptor
#1233GPRC5D chimeric antigen receptors and cells expressing the same
#1234Compositions and methods for treating cancer with anti-mesothelin immunotherapy
#1235Immunotoxins with albumin binding domain
#1236Chimeric antigen receptors and CAR-T cells that bind CXCR5 and methods of use thereof to treat medical disorders
#1237Chimeric antigen receptors with enhanced NFκB signaling
#1238T CELLS EXPRESSING A CHIMERIC ANTIGEN RECEPTOR
#1239Engineered T cell receptors and immune therapy using the same
#1240Method of inhibiting apoptosis or promoting cell survival by providing a bi-specific protein comprising insulin-like growth factor IGF-1 and Annexin A5
#1241COMBINATION CANCER THERAPY USING CHIMERIC ANTIGEN RECEPTOR ENGINEERED NATURAL KILLER CELLS AS CHEMOTHERAPEUTIC DRUG CARRIERS
#1242Methods and compositions for targeting tissue lesions
#1243BAFF-R antibodies and uses thereof
#1244HUMANIZED BCMA-CAR-T CELLS
#1245CS1 targeted chimeric antigen receptor-modified T cells for treatment of AL amyloidosis
#1246Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
#1247OCTS technology-based pancreatic cancer and malignant mesothelioma CAR-T therapeutic vector, construction method therefor, and use thereof
#1248Malignant glioma CAR-T therapeutic vector based on OCTS technology, and construction method and application thereof
#1249DHFR tunable protein regulation
#1250Antibodies and chimeric antigen receptors specific for CD19
#1251CD123-binding chimeric antigen receptors
#1252HLA-DR CAR-T COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
#1253Methods and compositions for protection against lentiviral infections
#1254NKT-cell subset for in vivo persistence and therapeutic activity and propagation of same
#1255Anti-epidermal growth factor receptor variant III chimeric antigen receptors and use of same for the treatment of cancer
#1256REMOVAL OF TARGET CELLS BY CIRCULATING VIRUS-SPECIFIC CYTOTOXIC T-CELLS USING MHC CLASS I COMPRISING COMPLEXES
#1257Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses
#1258Compositions and methods for treating cancer with anti-CD22 immunotherapy
#1259Modified cell expressing therapeutic agent and uses thereof
#1260Antitumor peptide and use thereof
#1261Therapeutic compounds and methods
#1262Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
#1263Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy
#1264Chimeric antigen receptor (CAR) comprising a CD19-binding domain
#1265Interleukin 15 (IL-15) variants
#1266Tropism-Modified Recombinant Viral Particles and Uses Thereof for the Targeted Introduction of Genetic Material into Human Cells
#1267Compositions for treating pathological calcification conditions, and methods using same
#1268ANTI-B-CELL MATURATION ANTIGEN CHIMERIC ANTIGEN RECEPTORS WITH HUMAN DOMAINS
#1269HEPATIC ARTERIAL INFUSION OF CAR-T CELLS
#1270Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders
#1271Truncated NKG2D chimeric receptors and uses thereof in natural killer cell immunotherapy
#1272Chimeric antigen receptors with mutated CD28 costimulatory domains
#1273Elimination of CD19-positive lymphoid malignancies by CD19-CAR expressing NK cells
#1274MULTIGENE CONSTRUCT FOR IMMUNE-MODULATORY PROTEIN EXPRESSION AND METHODS OF USE
#1275Antigen-specific immune effector cells
#1276Monoclonal antibody targeting a unique sialoglycosylated cancer-associated epitope of CD43
#1277Compositions and methods for treating cancer with anti-CD19 immunotherapy
#1278CSF1R-based chimeric proteins
#1279COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPIES
#1280CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
#1281Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof
#1282Antibody/T-cell receptor chimeric constructs and uses thereof
#1283Nucleic acid molecules encoding chimeric antigen receptors comprising a CD20 binding domain
#1284Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy
#1285Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy
#1286BCMA binding molecules and methods of use thereof
#1287Extracellular vesicle comprising a fusion protein having Fc binding capacity
#1288Antiviral peptide and use thereof
#1289Acoustic and ultrasound-based mechanogenetics and thermogenetics for immunotherapy
#1290ANTI-GPIIB/IIIA ANTIBODIES OR USES THEREOF
#1291CHIMERIC ANTIGEN RECEPTORS (CAR) AND METHODS FOR MAKING AND USING THE SAME
#1292Interferon alpha 2B variants
#1293Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC and other cancers
#1294Antigen-specific tolerance and compositions for induction of same
#1295PDE5 compositions and methods for immunotherapy
#1296METHODS OF TREATING T CELL EXHAUSTION BY INHIBITING OR MODULATING T CELL RECEPTOR SIGNALING
#1297Genomic engineering of pluripotent cells
#1298TRANSCRIPTION SYSTEM
#1299Antigen-binding fusion proteins with modified HSP70 domains
#1300Anti-CD30 antibodies and methods for treating CD30+ cancer
#1301Antigen binding receptors specific for mutated Fc domains
#1302THERAPEUTIC CELLS
#1303Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
#1304T CELL-TARGETED T CELLS
#1305Chimeric antigen receptor cells targeting ROBO1, preparation method and use thereof
#1306Compositions and methods for treating cancer with anti-CD19/CD22 immunotherapy
#1307CD40 AGONIST ANTIBODY /TYPE 1 INTERFERON SYNERGISTIC ADJUVANT COMBINATION, CONJUGATES CONTAINING AND USE THEREOF AS A THERAPEUTIC TO ENHANCE CELLULAR IMMUNITY
#1308Selective recovery
#1309Prostate-specific membrane antigen (PSMA) targeting peptides
#1310Compound comprising an autoantigenic peptide and a carrier with a MHC binding motif
#1311Immune cells expressing engineered antigen receptors
#1312METHODS FOR USE OF PROINSULIN TRANSFERRIN FUSION PROTEINS AS PRODRUGS
#1313Chimeric antigen receptors targeting CD37
#1314CD20 scFv-ELPs methods and therapeutics
#1315BCMA chimeric antigen receptors
#1316CRP capture/detection of gram positive bacteria
#1317Chimeric antigen receptors targeting BCMA and methods of use thereof
#1318MONOVALENT BLOOD BRAIN BARRIER SHUTTLE MODULES
#1319CAR T therapy through uses of co-stimulation
#1320CHIMERIC ANTIGEN RECEPTOR T CELLS (CAR-T) FOR THE TREATMENT OF CANCER
#1321Cartilage-homing peptide conjugates and methods of use thereof
#1322Norovirus S particle based vaccines and methods of making and using same
#1323Targeted disruption of the MHC cell receptor
#1324METHODS AND COMPOSITIONS OF TREATING AUTOIMMUNE DISEASES
#1325Immunomodulatory and differentiating function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy
#1326Anti-CD19 humanized antibody and immune effector cell targeting cd 19
#1327IL-31 improves efficacy of macrophage-based adoptive cell therapy for cancer
#1328IL2 and TNF mutant immunoconjugates
#1329CHIMERIC ANTIGEN RECEPTOR THERAPY CHARACTERIZATION ASSAYS AND USES THEREOF
#1330INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF ASPARAGINYL TRNA SYNTHETASES
#1331Targeted TGFβ inhibition
#1332CELLS EXPRESSING A BCMA-TARGETING CHIMERIC ANTIGEN RECEPTOR, AND COMBINATION THERAPY WITH A GAMMA SECRETASE INHIBITOR
#1333Targeted mutant interferon-gamma and uses thereof
#1334Cell
#1335Soluble and immunoreactive flaviviral NS1 polypeptides comprising the wing domain
#1336Soluble and immunoreactive Zika virus NS1 polypeptides comprising the wing domain
#1337CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE
#1338Fusion protein for restoring the functions of failing immune cells and application thereof
#1339SECRETABLE VARIANT IMMUNOMODULATORY PROTEINS AND ENGINEERED CELL THERAPY
#1340PSMA-specific binding proteins
#1341Co-stimulatory domains for use in genetically-modified cells
#1342Chimeric immunogenic polypeptides
#1343Chimeric antigen receptors (CARs), compositions and methods thereof
#1344CELL-TARGETING MOLECULES COMPRISING DE-IMMUNIZED, SHIGA TOXIN A SUBUNIT EFFECTORS AND CD8+ T-CELL EPITOPES
#1345PLASMA CELL CYTOKINE VEHICLE CONTAINING FUSION PROTEINS FOR TARGETED INTRODUCTION OF SIRNA INTO CELLS AND TISSUES
#1346TNFRSF14 / HVEM proteins and methods of use thereof
#1347Modified biotin, streptavidin mutant, and usage of them
#1348TREATMENT FOR BK POLYOMAVIRUS INFECTION
#1349CHIMERIC ANTIGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USE THEREOF
#1350Serine protease molecules and therapies
#13515T4-targeting agents and methods
#1352Immunomodulatory fusion proteins and uses thereof
#1353Transgenic macrophages, chimeric antigen receptors, and associated methods
#1354CS1-specific chimeric antigen receptor engineered immune effector cells
#1355Chimeric transmembrane proteins and uses thereof
#1356Construction of chimeric antigen receptor targeting CD20 antigen and activity identification of engineered T cells thereof
#1357CD20-BINDING IMMUNOTOXINS FOR INDUCING CELLULAR INTERNALIZATION AND METHODS USING SAME
#1358Donor repair templates multiplex genome editing
#1359BCMA (CD269) specific chimeric antigen receptors for cancer immunotherapy
#1360CONSTRUCTION AND APPLICATION OF RECOMBINANT GENE FOR CHIMERIC ANTIGEN RECEPTOR FOR TREATING HIV INFECTION
#1361Heterologous targeting peptide grafted AAVS
#1362CD28 compositions and methods for chimeric antigen receptor therapy
#1363Fusion proteins and use thereof for preparing vaccines
#1364Immune cells expressing an antigen binding receptor and a chimeric costimulatory receptor
#1365Antigen-binding molecules comprising a tumor necrosis factor (TNF) family ligand trimer
#1366BCMA chimeric antigen receptors and uses thereof
#1367Erythrocyte-binding therapeutics
#1368CSF1R-CD40L chimeric proteins
#1369Zika as a cell penetrating peptide for delivery to the brain
#1370Compositions for treatment of wet age-related macular degeneration
#1371NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF
#1372Botulinum neurotoxins with modified light chain specificity and methods for producing same
#1373Chimeric polypeptides and their use in bacterial decolonization
#1374Methods of modulating expression of target nucleic acid sequences in a cell
#1375ANTIGEN-BINDING PROTEINS TARGETING MELANOMA DIFFERENTIATION ANTIGENS AND USES THEREOF
#1376MUC16 specific chimeric antigen receptors and uses thereof
#1377Monoclonal antibody which specifically recognizes B cell lymphoma and use thereof
#1378EFFECTIVE GENERATION OF TUMOR-TARGETED T CELLS DERIVED FROM PLURIPOTENT STEM CELLS
#1379PROTEINS BINDING BCMA, NKG2D AND CD16
#1380Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC and other cancers
#1381Methods and therapeutics comprising ligand-targeted ELPs
#1382Zika virus vaccines
#1383COMBINATION THERAPY OF TUMOR-TARGETED IL-2 VARIANT IMMUNOCYTOKINES AND ANTIBODIES AGAINST HUMAN PD-L1
#1384Oncolytic virotherapy and immunotherapy
#1385TIM3-binding chimeric antigen receptors
#1386CTLA4/PD1 targeted/immunomodulatory fusion proteins
#1387Bispecific signaling agents and uses thereof
#1388VC-CAR molecule and use thereof in removing HIV-1 infected cells
#1389Recombinant polypepties for membrane fusion and uses thereof
#1390Regulating chimeric antigen receptors
#1391Natural killer cell expressing anti-cotinine chimeric antigen receptor
#1392Fractal combination therapy
#1393Coordinating gene expression using RNA destabilizing elements
#1394Materials and methods for engineering cells and uses thereof in immuno-oncology
#1395Materials and methods for engineering cells and uses thereof in immuno-oncology
#1396Chimeric antigen receptors and uses thereof
#1397BCMA-targeting antibody and use thereof
#1398Antibody targeting IL-13RA2 and use thereof
#1399Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
#1400Red blood cell targeted factor VIII and method of using the same
#1401CHIMERIC T CELL ANTIGEN RECEPTORS AND METHODS OF USE THEREOF
#1402Clec9A binding agents
#1403Fusion protein comprising a blood-brain barrier (BBB)-crossing single domain antibody Fc5, an immunoglobulin Fc fragment and a beta-amyloid binding polypeptide (ABP)
#1404Universal chimeric antigen expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
#1405Helix-grafted proteins as inhibitors of disease-relevant protein-protein interactions
#1406Coordinating gene expression using RNA destabilizing elements
#1407DENDRITIC CELL PREPARATIONS, COMPOSITIONS THEREOF AND METHODS OF USING SAME
#1408ASPARTATE BETA-HYDROXYLASE CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
#1409Chimeric proteins and methods of immunotherapy
#1410Phage conjugates and uses thereof
#1411Therapeutic agents targeting CLPTM1
#1412Exosome delivery system
#1413Therapeutic biologic for treatment of hepatocellular carcinoma
#1414CELL DEATH INDUCING CHIMERIC ANTIGEN RECEPTORS
#1415Peptides and combinations of peptides for use in immunotherapy against lung cancer, including NSCLC and other cancers
#1416Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC and other cancers
#1417Peptides and combination of peptides for use in immunotherapy against NHL and other cancers
#1418CHIMERIC ANTIGEN RECEPTOR AND NATURAL KILLER CELLS EXPRESSING SAME
#1419Methods and compositions relating to ex vivo culture and modulation of T cells
#1420CD229 CAR T cells and methods of use thereof
#1421Tunable Chimeric Antigen Receptors
#1422Compositions and Methods for Modulating the Immune System
#1423Chimeric antigen receptors based on alternative signal 1 domains
#1424NOVEL IMMUNOCONJUGATES
#1425GHR-106 CHIMERIC ANTIGEN RECEPTOR CONSTRUCT AND METHODS OF MAKING AND USING SAME
#1426Antibody to programmed death-ligand 1 (PD-L1) and use thereof
#1427Compositions and methods for inhibition of lineage specific antigens
#1428Immunoconjugates
#1429ADAPTER CHIMERIC ANTIGEN RECEPTOR EXPRESSING CELLS FOR TARGETING OF MULTIPLE ANTIGENS
#1430Virus-like particles with high-density coating for inducing the expression of antibodies
#1431SYNTHETIC ADENOVIRUSES TARGETING BONE TISSUE AND USES THEREOF
#1432Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
#1433Peptides and combination of peptides for use in immunotherapy against NHL and other cancers
#1434Materials and methods for engineering cells and uses thereof in immuno-oncology
#1435Materials and methods for engineering cells and uses thereof in immuno-oncology
#1436TLR9-binding chimeric antigen receptors
#1437SIGNAL TRANSDUCTION MODIFYING PROTEIN
#1438Recombinant protein-based method for the delivery of silencer RNA to target the brain
#1439Anti-abeta therapeutic vaccines
#1440Chimeric antigen receptor therapy with reduced cytotoxicity for viral disease
#1441HUMAN IgG Fc DOMAIN VARIANTS WITH IMPROVED EFFECTOR FUNCTION
#1442Engineered CD46-specific effector cells and uses thereof in the treatment of cancer
#1443PHAGE DERIVED ANTIMICROBIAL ACTIVITIES
#1444Anti-alpha-synuclein antibodies and methods of use
#1445CELL EXPRESSING CAR AND GPCR
#1446Selective recovery
#1447Fusion protein for use in the treatment of HvG disease
#1448COMPOSITIONS AND METHODS FOR T-CELL AND CYTOKINE ACTIVATION
#1449T cell receptor-like antibodies specific for Foxp3-derived peptides
#1450IL2 and TNF immunoconjugates
#1451Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy
#1452Bifunctional polypeptides
#1453Genomic engineering of pluripotent cells
#1454Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC and other cancers
#1455Re-directed immunotherapy
#1456Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
#1457Compound and method for treating myotonic dystrophy
#1458BAFF-R targeted chimeric antigen receptor-modified t-cells and uses thereof
#1459Oncolytic HSV vector
#1460Serine protease molecules and therapies
#1461Immunotherapy compositions and methods
#1462Expression of chimeric polypeptide with variable lymphocyte receptors on immune cells and uses for treating cancer
#1463Compositions and methods for TCR reprogramming using fusion proteins
#1464Fusion proteins with extended serum half life
#1465Recombinant chimeric antigen receptor gene and use thereof
#1466Conjugates for targeted cell surface editing
#1467Drug regulated transgene expression
#1468Programmable protein circuits in living cells
#1469A UNIVERSAL PLATFORM FOR CAR THERAPY TARGETING A NOVEL ANTIGENIC SIGNATURE OF CANCER
#1470Antibody/T-cell receptor chimeric constructs and uses thereof
#1471Use of Triplex CMV Vaccine in CAR T Cell Therapy
#1472Coordinating gene expression using RNA destabilizing elements
#1473Chimeric antigen receptors targeting B-cell maturation antigen
#1474Platform for enhanced targeted delivery
#1475Chimeric antigen receptor for efficient selective proliferation in vitro and uses thereof
#1476Chimeric antigen receptors targeting CD70
#1477Chimeric antigen receptor (CAR) that targets chemokine receptor CCR4 and its use
#1478Co-stimulatory domains for use in genetically-modified cells
#1479Bifunctional polypeptides
#1480Bifunctional polypeptides
#1481Compositions for treating pathological calcification conditions, and methods using same
#1482Therapeutic multi-targeting constructs and uses thereof
#1483Nanobody based imaging and targeting of ECM in disease and development
#1484Methods of using low dose volume B-cell epitope compositions for inducing an antibody immune response in human subjects
#1485Adeno-associated virus virions with variant capsid
#1486Fusion protein, polynucleotide, genetic construct, producer, preparation for regeneration of cartilage
#1487Antimicrobial fusion proteins comprising an endolysin and an amphipathic peptide segment
#1488Compositions and methods for treating cancer with anti-mesothelin immunotherapy
#1489Targeted effector proteins and uses thereof
#1490Transduction
#1491Adoptive t-cell therapy
#1492COMPOSITIONS FOR AND METHODS OF TREATING AND PREVENTING CANCER TARGETING TUMOR ASSOCIATED CARBOHYDRATE ANTIGENS
#1493Modified cell expansion and uses thereof
#1494Methods for protein modification in pharmaceutical applications
#1495Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
#1496Chimeric antigen receptors targeting CD-19
#1497METHOD OF TREATING SYSTEMIC FIBROTIC DISORDERS USING AN IL-33/TNF BISPECIFIC ANTIBODY
#1498Compositions and methods for treating HIV/AIDS with immunotherapy
#1499Bacteria-based protein delivery
#1500GENETICALLY-MODIFIED CELLS COMPRISING A MODIFIED HUMAN T CELL RECEPTOR ALPHA CONSTANT REGION GENE