Methods of making bispecific anti-CD307E and anti-BCMA chimeric antigen receptors and uses of the same

Antibody fusion protein and related compositions for targeting cancer

Vesicles comprising lectins expressed on the surface and methods of use thereof to deliver an agent to autophagic and apoptotic cells

MULTIMERIC DEFENSIN PROTEINS AND RELATED METHODS

TLR9 targeted therapeutics

Factor IX polypeptides and methods of use thereof

Factor IX polypeptides and methods of use thereof

Binding molecules with modified J-chain

Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS

Natural killer cell function enhancer

Compositions and methods for inhibiting T cell exhaustion

Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy

Methods for making novel antigen binding domains

Compositions and methods for TCR reprogramming using fusion proteins

Chimeric antigen receptor

Anti-annexin A2 monoclonal antibodies

Modified T lymphocytes comprising a BAFF antibody-inducible caspase and methods of apoptosis

Combination immune therapy and cytokine control therapy for cancer treatment

T cells for expression of chimeric antigen receptors and other receptors

Immunotherapy methods using anti-PD-L1 antibodies in combination with EGFR1 targeted-TGF-beta immunomodulatory fusion proteins

Targeting PD-L1 on tumor cells

Optimized PNE-based chimeric receptor T cell switches and uses thereof

Method of protecting tissue from damage by administering a bi-specific therapeutic protein comprising insulin-like growth factor 1 (IGF-1) and Annexin A5

IL22 immunoconjugates

CSF1R-based chimeric proteins

Immunomodulatory and differentiating function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy

Chimeric antigen receptors specific for B-cell maturation antigen and encoding polynucleotides

Affinity-enhanced monomeric streptavidin chimeric antigen receptor (CAR)

Anti-BCMA chimeric antigen receptor

MHC Class I Epitope Delivering Polypeptides

Combination of lenalidomide and polypeptide construct, and uses thereof

Compositions and methods of cellular immunotherapy

POLYNUCLEOTIDE ENCODING FUSION OF ANCHORING MOTIF AND DEHALOGENASE, HOST CELL INCLUDING THE POLYNUCLEOTIDE, AND USE THEREOF

Bi-functional chimeric proteins and uses thereof

Chimeric antigen receptors targeting epidermal growth factor receptor variant III

Core domain of annexins and uses thereof in antigen delivery and vaccination

Selective recovery

Engineered T cell receptors and immune therapy using the same

Compositions and methods for anti-staphylococcal biologic agents

Glucagon/GLP-1 receptor co-agonists

DEVICES, SYSTEMS AND METHODS FOR OPTOGENETIC MODULATION OF ACTION POTENTIALS IN TARGET CELLS

Use of trans-signaling approach in chimeric antigen receptors

Chimeric antigen receptors

HLA-G AS A NOVEL TARGET FOR CAR T-CELL IMMUNOTHERAPY

Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker

Compositions and methods for tumor transduction

Polypeptide compositions comprising spacers

Anti-CD38 antibodies and methods of use

Compositions and methods for CD20 immunotherapy

Compositions and methods for treating cancer with anti-CD19 immunotherapy

METABOLICALLY ACTIVATED RECOMBINANT VIRAL VECTORS AND METHODS FOR THEIR PREPARATION AND USE

Multimeric bispecific binding molecules specific for CD20 and CD3

T cell modification and use thereof

Compositions and methods for targeted cytokine delivery

Amphipathic peptide

Polyethylenimine (PEI)-polypeptide conjugates and methods of use thereof

Peptides and combination of peptides and scaffolds for use in immunotherapy against Renal Cell Carcinoma (RCC) and other cancers

Peptides and combination of peptides and scaffolds for use in immunotherapy against Renal Cell Carcinoma (RCC) and other cancers

Methods and compositions for car T cell therapy

COMPOSITIONS, METHODS, AND COMPUTER SYSTEMS RELATED TO MAKING AND ADMINISTERING MODIFIED T CELLS

Anti-Sialyl Tn chimeric antigen receptors

Antibodies and related molecules and uses thereof

Compositions and methods for generating a persisting population of T cells useful for the treatment of cancer

Peptides and combination of peptides for use in immunotherapy against NHL and other cancers

Peptides and combination of peptides for use in immunotherapy against NHL and other cancers

CD8 binding agents

TNFRSF14 / HVEM proteins and methods of use thereof

Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses

Peptides and combination of peptides for use in immunotherapy against NHL and other cancers

IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME

Flag tagged CD19-CAR-T cells

Targeting tissue factor to activated platelets

Composition and Method for Therapeutic Agent Delivery During Pregnancy

CHEMOKINE-IMMUNOGLOBULIN FUSION POLYPEPTIDES, COMPOSITIONS, METHOD OF MAKING AND USE THEREOF

Composition for overcoming resistance to EGFR-targeting agent

Eliminating MHC restriction from the T cell receptor as a strategy for immunotherapy

OMA1 activity assay

Broadly neutralizing anti-HIV-1 antibodies that bind to an N-glycan epitope on the envelope

ANTI-CD37 CHIMERIC ANTIGEN RECEPTORS AND IMMUNE CELLS EXPRESSING THEM

Heterodimers of IL-15 and IL-15R alpha to increase thymic output and to treat lymphopenia

Antibody against glypican-3 and application thereof

Cadherin-17 specific antibodies and cytotoxic cells for cancer treatment

Compositions and methods for inhibition of lineage specific antigens

Compositions and methods for inhibition of lineage specific antigens

T cell receptor-deficient chimeric antigen receptor T-cells and methods of use thereof

Method to enhance the efficiency of systemic AAV gene delivery to the central nervous system

Antibody/T-cell receptor chimeric constructs and uses thereof

Antigen binding regions against fibronectin type III domains and methods of using the same

ADHERENT CANCER CELL LINE EXPRESSING A HEMATOLOGICAL TUMOR ANTIGEN

Composition comprised of antigen linked to a TNF superfamily ligand

Conditionally active chimeric antigen receptors for modified t-cells

Fusokines involving cytokines with strongly reduced receptor binding affinities

Compositions comprising chemerin and methods of use thereof

Therapeutic agents

Lymphocyte cell lines and uses thereof

Compositions and methods for generating a persisting population of T cells useful for the treatment of cancer

HIGH AFFINITY NY-ESO T CELL RECEPTORS

Chimeric antigen receptor targeting human NKG2DL and methods of preparing said receptor and pharmaceutical composition

Expression of novel cell tags

RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTOR 1 (ROR1) SINGLE CHAIN FV ANTIBODY FRAGMENT CONJUGATES AND METHODS OF USE THEREOF

Single chain fusionconstructs comprising multimeric antibody fragments fused to collagen trimerization domains

Therapeutic biologic for treatment of hepatocellular carcinoma

Methods and compositions for reducing the immunogenicity of chimeric notch receptors

Chimeric antigen receptors targeting B-cell maturation antigen and uses thereof

Method employing bispecific protein complex

Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy

Anti-human ADRB3 monoclonal antibody and application thereof in disease diagnosis and treatment

Compositions and methods for internalizing enzymes

METHODS AND MATERIALS FOR GENERATING T CELLS

Binding-triggered transcriptional switches and methods of use thereof

Genetically modified cells and uses thereof

Chimeric antigen receptor cell preparation and uses thereof

Cell

Chimeric proteins and methods of immunotherapy

Peptides and combination of peptides and scaffolds for use in immunotherapy against Renal Cell Carcinoma (RCC) and other cancers

Targeted immunotolerance

Methods to spatially profile protease activity in tissue and sections

Transgenic macrophages, chimeric antigen receptors, and associated methods

TARGETING OF CYTOKINE ANTAGONISTS

Targeting of human interferon antagonists

Dps fusion proteins for use in vaccines and diagnostics

Chimeric polypeptides and their use in bacterial decolonization

Methods and compositions for reducing immunosupression by tumor cells

Tumor-specific anti-EGFR antibody and application thereof

Chimeric antigen receptors targeting HER2

Processable single chain molecules and polypeptides made using same

PSMA-specific binding proteins

Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)

Treatment of cancer using a CD123 chimeric antigen receptor

Humanized antigen-binding domains and methods of use

Transforming growth factor-beta-responsive polypeptides and their methods for use

IL-15 and IL-15Rα sushi domain based immunocytokines

B-cell receptor complex binding proteins containing T-cell epitopes

DRUG DELIVERY SYSTEMS USING FC FRAGMENTS

Trispecific molecule combining specific tumor targeting and local immune checkpoint inhibition

Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof

Anti-podocalyxin antibodies and methods of using the same

Method of treating cancer with compositions comprising IL-31

CELL-TARGETING MOLECULES COMPRISING AMINO-TERMINUS PROXIMAL OR AMINO-TERMINAL, SHIGA TOXIN A SUBUNIT EFFECTOR REGIONS

SECRETORY TNT CAR CELL IMMUNOTHERAPY

CHIMERIC ANTIGEN RECEPTOR, REGULATORY CELLS AND METHODS OF USE

Anti-GD3 specific chimeric antigen receptors for cancer immunotherapy

Use of IL-15 to increase thymic output and to treat lymphopenia

CAR-EXPRESSING NK-92 CELLS AS CELL THERAPEUTIC AGENTS

Methods to protect transplanted tissue from rejection

ANTIGEN RECEPTORS AND USES THEREOF

Therapeutic compounds and methods

Targeted protein contrast agents, methods of making, and uses thereof

Plasma cell cytokine vehicle containing fusion proteins for targeted introduction of siRNA into cells and tissues

Anti-TIGIT anibodies, anti-PVRIG antibodies and combinations thereof

Deimmunized therapeutic compositions and methods

MODIFIED T LYMPHOCYTES HAVING IMPROVED SPECIFICITY

Bispecific HER2 and CD3 binding molecules

CD3 binding polypeptides

Immune cell compositions and methods of use

ERG targeted therapy

Costimulatory chimeric antigen receptor T cells targeting IL13Rα2

ANTI-CD19 scFv (FMC63) POLYPEPTIDE AND USES THEREOF

Heterologous targeting peptide grafted AAVS

METHODS FOR CONTROLLING T CELL PROLIFERATION

Method of redirecting T cells to treat HIV infection

Core constructs and their uses in configuring pharmaceutical molecules

CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS AS THERAPEUTIC INTERVENTIONS FOR AUTO- AND ALLO-IMMUNITY

CYTOTOXIC PROTEINS COMPRISING CELL-TARGETING BINDING REGIONS AND SHIGA TOXIN A SUBUNIT REGIONS FOR SELECTIVE KILLING OF SPECIFIC CELL TYPES

De-Immunized, Shiga Toxin A Subunit Scaffolds and Cell-Targeting Molecules Comprising the Same

Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers

METHODS AND COMPOSITIONS FOR TREATMENT OF POMPE DISEASE

METHODS AND COMPOSITIONS FOR INCREASING IDURONATE 2-SULFATASE ACTIVITY IN THE CNS

Tumor infiltrating lymphocytes for treatment of cancer

T cell receptors (TCR) and uses thereof for the diagnosis and treatment of diabetes

EPHA3 and multi-valent targeting of tumors

CELL-TARGETING MOLECULES COMPRISING SHIGA TOXIN A SUBUNIT EFFECTORS AND CD8+ T-CELL EPITOPES

Methods and compositions for cells expressing a chimeric intracellular signaling molecule

Anti-alpha-synuclein antibodies and methods of use

LECTIN COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE TO AN ANTIGEN

Cells for immunotherapy engineered for targeting CD38 antigen and for CD38 gene inactivation

Quality of immunological synapse predicts effectiveness of chimeric antigen receptor (CAR) T cells

Compositions and methods for TCR reprogramming using fusion proteins

Antibodies to MUC16 and methods of use thereof

Chimeric antigen receptors based on single domain antibodies and methods of use thereof

CD70 binding molecules and methods of use thereof

VEGFR-2 car immune cells to treat cancers

Antibody

Selective recovery

Factor IX Polypeptides and Methods of Use Thereof

Factor IX polypeptides and methods of use thereof

Humanized antibodies

Use of chimeric antigen receptor modified cells to treat cancer

Exposed collagen-targeted fusion cytokine for immune modulation in invasive cancers and lesions of infections

Anti-CD70 chimeric antigen receptors

Compositions and methods for treating cancer with anti-mesothelin immunotherapy

Binding-triggered transcriptional switches and methods of use thereof

Factor IX Polypeptides and Methods of Use Thereof

Serine protease molecules and therapies

GPC3 and ASGPR1 double-targeted transgenic immune effector cell and use thereof

PHARMACEUTICAL COMPOSITION THAT IS ANTICANCER AND SUPPRESSES CANCER METASTASIS, CONTAINING, AS ACTIVE INGREDIENT, FUSION PEPTIDE SIMULTANEOUSLY TARGETING CANCER CELL AND TUMOR ASSOCIATED MACROPHAGE

COMBINATION THERAPY OF TUMOR-TARGETED IL-2 VARIANT IMMUNOCYTOKINES AND ANTIBODIES AGAINST HUMAN PD-L1

Cancer specific-splicing ribozyme and use thereof

NOVEL VACCINES IN PREVENTION AND TREATMENT OF MALARIA

Antigen-specific tolerance and compositions for induction of same

Compositions for generation of immune tolerance to specific antigens

Compositions for inducing antigen-specific tolerance

METHODS AND COMPOSITIONS FOR TREATING HIV

Blockade of CD7 expression and chimeric antigen receptors for immunotherapy of T-cell malignancies

Monoclonal antibody which specifically recognizes B cell lymphoma and use thereof

Glycan-dependent immunotherapeutic molecules

Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof

Anti-tumor medicament based on adenovirus

Modified NK-92 cells for treating cancer

Fusokines involving cytokines with strongly reduced receptor binding affinities

Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics

ABERRANT CELL-RESTRICTED IMMUNOGLOBULINS PROVIDED WITH A TOXIC MOIETY

Fusion proteins that facilitate cancer cell destruction

T cell receptor-like antibodies specific for a PRAME peptide

SOLUBLE FGFR3 DECOYS FOR TREATING SKELETAL GROWTH DISORDERS

Anti-cancer fusion polypeptides, encoding nucleic acids and methods of using polypeptides

Compositions and methods for treatment of cancer

Anti-tumor peptides and use thereof

Laser-assisted intradermal administration of active substances

Enzymatic immunomodulation of solid tumors and uses thereof

Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

MEMBRANE-RECEIVER COMPLEX THERAPEUTICS

Human monoclonal antibodies specific for glypican-3 and use thereof

Insertable variable fragments of antibodies and modified α1-α2 domains of NKG2D ligands, and non-natural NKG2D ligands that bind non-natural NKG2D receptors

A Novel Complex Comprising A Cell Penetrating Peptide, A Cargo And A TLR Peptide Agonist For Treatment Of Glioblastoma

Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells

Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

Engineered toxin adapted to deliver molecules into selected cells

Lysosomal targeting peptides and uses thereof

Nucleic acid molecules encoding chimeric antigen receptors comprising a CD20 binding domain

FLT3 directed car cells for immunotherapy

Sensor systems for target ligands and uses thereof

Bispecific multivalent fusion proteins

EGFR-directed car therapy for glioblastoma

AGENTS, SYSTEMS AND METHODS FOR TREATING CANCER

Fusion polypeptide for immuno-enhancement and method for enhancing stimulation of immune response using the same

NUCLEIC ACID CONSTRUCT FOR EXPRESSING MORE THAN ONE CHIMERIC ANTIGEN RECEPTOR

NUCLEIC ACID CONSTRUCT FOR EXPRESSING MORE THAN ONE CHIMERIC ANTIGEN RECEPTOR

Targeting GIV-GEF-GI signaling for treating diverse diseases

Immunogenic Listeria-Based Compositions Comprising Truncated Acta-Antigen Fusions And Methods Of Use Thereof

Nucleic acid construct

Erythrocyte-binding therapeutics

Nucleic acid construct

Compositions and Methods for Diagnosing and Treating Cancer

Antigen binding molecules specific for an anti-CD19 scFv

Stabilized single human CD4 domains and fusion proteins

Antibody/T-cell receptor chimeric constructs and uses thereof

Chimeric antigen receptor and methods of use thereof

Binding-triggered transcriptional switches and methods of use thereof

IL2 and TNF immunoconjugates

Recombinant TNF ligand family member polypeptides with antibody binding domain and uses thereof

METHODS AND COMPOSITIONS FOR TREATING CANCER

HIGH AFFINITY NY-ESO T CELL RECEPTORS

Anti-B7-H6 antibody, fusion proteins, and methods of using the same

Epidermal growth factor receptor targeted/immunomodulatory fusion proteins and methods of use for them

Chimeric antigen receptors (CARs), targeting hematologic malignancies, compositions and methods of use thereof

TARGETING TRASTUZUMAB-RESISTANT HER2+ BREAST CANCER WITH A HER3-TARGETING NANOPARTICLE

Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers

Compositions for treating pathological calcification conditions, and methods using same

Compositions for treating pathological calcification conditions, and methods using same

Compositions for treating pathological calcification conditions, methods, and host cells using the same

Targeting of human interferon antagonists

NOVEL ANTIBODY-ALBUMIN-DRUG CONJUGATES (AADC) AND METHODS FOR USING THEM

Targeted therapeutic proteins

Anti-inflammatory molecules with tissue-targeting functions

Treatment of cancer using a CD33 chimeric antigen receptor

Chimeric antigen receptor (CAR) comprising a CD19-binding domain

Antibody-mediated transduction of heat shock proteins into living cells

Fusion proteins comprising a binding protein and an interleukin-15 polypeptide having a reduced affinity for IL15Ra and therapeutic uses thereof

Amphipathic peptide

Chimeric antigen receptor and methods of use thereof

Chimeric antigen receptors specific for carbonic acid anhydrase IX

Tumor targeted TNF-related apoptosis inducing ligand fusion polypeptide, methods and uses therefor

Recombinant self-assembling protein comprising target-oriented peptide and use thereof

METHODS AND COMPOSITIONS FOR TREATMENT OF FORBES-CORI DISEASE

Adoptive T-cell therapy using EMPD-specific chimeric antigen receptors for treating IgE-mediated allergic diseases

Bi-specific chimeric antigen receptor and uses thereof

Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy

Engineered T cells and uses therefor

Method and compositions for cellular immunotherapy

CHIMERIC ANTIGEN RECEPTOR TARGETING OF TUMOR ENDOTHELIUM

Chimeric antigen receptors, compositions, and methods

TARGETED TGFß INHIBITION

Fusion proteins comprising an anti-CD40 antibody and cancer antigens

exotoxin A with less immunogenic T cell and/or B cell epitopes

Bi-functional allosteric protein-drug molecules for targeted therapy

Multitargeting onocolytic adenovirus, methods of use, and methods of making

Site-specific DNA recombination

Engineered microbe-targeting molecules and uses thereof

Methods and compositions for transducing lymphocytes and regulating the activity thereof

Anti-GPIIB/IIIA antibodies and uses thereof

Conjugated knottin mini-proteins containing non-natural amino acids

Compositions and methods for improved car-T cell therapies

Class of therapeutic protein based molecules

Glucagon/GLP-1 receptor co-agonists

METHODS AND COMPOSITIONS FOR TREATING BRAIN DISEASES

ANTI-CD19 scFv (FMC63) POLYPEPTIDE

ANTI-GLYCOPROTEIN IIb/IIIa ANTIBODIES

Construction and characterization of multimeric IL-15-based molecules with CD3 binding domains

Efficient delivery of therapeutic molecules in vitro and in vivo