97337 ⎘
Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Compositions for treating pathological calcification conditions, and methods using same
#1802Compositions for treating pathological calcification conditions, and methods using same
#1803Chimeric antigen receptor and methods of use thereof
#1804Methods for making novel antigen binding domains
#1805CHIMERIC PROTEIN
#1806Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene
#1807TETRAVALENT TLR9 BISPECIFIC ANTIBODY
#1808FUSION PROTEINS CONTAINING RECOMBINANT CYTOTOXIC RNASES
#1809METHOD FOR TARGETED INTRAPROSTATIC ADMINISTRATION OF PRX302 FOR TREATMENT OF PROSTATE CANCER
#1810Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene
#1811GENE MODIFIED IMMUNE EFFECTOR CELLS AND ENGINEERED CELLS FOR EXPANSION OF IMMUNE EFFECTOR CELLS
#1812Diagnosis and treatment of cancer expressing ILT3 or ILT3 ligand
#1813Designer collagens and use thereof
#1814COMPOSITIONS AND METHODS FOR LONG ACTING PROTEINS
#1815Compositions and methods for inhibition of lineage specific antigens
#1816CS1-specific chimeric antigen receptor engineered immune effector cells
#1817Cytokine-based fusion proteins for treatment of immune disorders
#1818Phage derived antimicrobial activities
#1819Monoclonal antibody which specifically recognizes B cell lymphoma and use thereof
#1820CHIMERIC ACTIVATORS: QUANTITATIVELY DESIGNED PROTEIN THERAPEUTICS AND USES THEREOF
#1821IL22 immunoconjugates
#1822Tumor necrosis factor-related apoptosis-inducing ligand variant, as well as a preparation method and use thereof
#1823Fusion protein, nanoparticle composed of a plurality of monomers of said fusion protein, and uses thereof
#1824Multivalent and monovalent multispecific complexes and their uses
#1825Methods and compositions for transducing lymphocytes and regulated expansion thereof
#1826Peptides and combination of peptides for use in immunotherapy against NHL and other cancers
#1827BCMA binding molecules and methods of use thereof
#1828Chimeric receptors and methods of use thereof
#1829ROR1 (NTRKR1) specific chimeric antigen receptors for cancer immunotherapy
#1830Nanobodies suitable for neuron regeneration therapy
#1831Chimeric antigen receptor specific for SSEA4 antigen
#1832MODIFIED MICROBIAL TOXIN RECEPTOR FOR DELIVERING AGENTS INTO CELLS
#1833CONJUGATES INCLUDING AN ANTIBODY MOIETY, A POLYPEPTIDE THAT TRAVERSES THE BLOOD-BRAIN BARRIER, AND A CYTOTOXIN
#1834Chimeric antigen and T cell receptors and methods of use
#1835Trophoblast glycoprotein (5T4, TPBG) specific chimeric antigen receptors for cancer immunotherapy
#1836Chimeric antigen receptors targeting Fc receptor-like 5 and uses thereof
#1837Fusion protein comprising albumin and retinol-binding protein
#1838Oncolytic HSV vector
#1839Tagged chimeric effector molecules and receptors thereof
#1840Transgene genetic tags and methods of use
#1841Chimeric antigen receptors to control HIV infection
#1842Cell-targeted cytotoxic constructs
#1843Construct for the delivery of a molecule into the cytoplasm of a cell
#1844CARCINOMA HOMING PEPTIDE (CHP), ITS ANALOGS, AND METHODS OF USING
#1845Method for efficient delivery of therapeutic molecules in vitro and in vivo
#1846T-cell redirecting bispecific antibodies for treatment of disease
#1847Compositions and methods for boosting the efficacy of adoptive cellular immunotherapy
#1848Reagents and methods for identifying, enriching, and/or expanding antigen-specific T cells
#1849Selective recovery
#1850Universal chimeric antigen expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
#1851Cleavage-activatable interferon-alpha proprotein
#1852Prostate-specific membrane antigen (PSMA) targeting peptides
#1853Targeted/TGF-ßRII fusion proteins and methods for making same
#1854Fusions of antibodies to CD38 and attenuated interferon alpha
#1855ROR1 specific multi-chain chimeric antigen receptor
#1856Modified meningococcal fHbp polypeptides
#1857Development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies
#1858FUSION PROTEINS, USES THEREOF AND PROCESSES FOR PRODUCING SAME
#1859Chimeric antigen receptors targeting epidermal growth factor receptor variant III
#1860Engineered cells for adoptive cell therapy
#1861Selective recovery
#1862Combination of lenalidomide and polypeptide construct, and uses thereof
#1863BCMA (CD269) specific chimeric antigen receptors for cancer immunotherapy
#1864Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
#1865CD40 ligand fusion protein vaccine
#1866Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
#1867Targeted disruption of the MHC cell receptor
#1868Drug regulated transgene expression
#1869Targeted interferons demonstrate potent apoptotic and anti-tumor activities
#1870Modified biotin, streptavidin mutant, and usage of them
#1871Chimeric antigen receptor and methods of use thereof
#1872Methods for improving the efficacy and expansion of immune cells
#1873Compositions and methods for rendering tumor cells susceptible to CD8+ T cell-mediated killing
#1874Methods for cancer therapy using mutant light molecules with increased affinity to receptors
#1875C6S specific transporter molecules
#1876CAR-expressing NK-92 cells as cell therapeutic agents
#1877USING B-CELL-TARGETING ANTIGEN IGG FUSION AS TOLEROGENIC PROTEIN THERAPY FOR TREATING ADVERSE IMMUNE RESPONSES
#1878Anti-alpha-synuclein antibodies and methods of use
#1879Keratan sulfate specific transporter molecules
#1880Chimeric antigen receptors targeting CD-19
#1881Cell-targeting molecules comprising protease-cleavage resistant, Shiga toxin A subunit effector polypeptides and carboxy-terminal moieties
#1882Lentiviral vectors
#1883Bi-specific annexin A5/IGF-1 proteins and methods of use thereof to promote regeneration and survival of tissue
#1884Bispecific peptide conjugate and radioactive bispecific peptide imaging agent
#1885Immunoconjugates
#1886High affinity NY-ESO T cell receptors
#1887Lectin compositions and methods for modulating an immune response to an antigen
#1888Modular antigen transportation molecules and uses thereof in animals
#1889Antibody-fynomer conjugates
#1890REGULATABLE CHIMERIC ANTIGEN RECEPTOR
#1891Targeting of chondroitin sulfate glycans
#1892Method for treating prostatitis utilizing the pore-forming protein proaerolysin PRX302
#1893Cell surface coupling of nanoparticles
#1894Transduction
#1895Methods of delivering a polypeptide molecule to Otx2 target cells using an Otx2 targeting peptide
#1896Engineered antibody-interferon mutant fusion molecules
#1897Methods and compositions for the packaging of nucleic acids into microglial exosomes for the targeted expression of polypeptides in neural cells
#1898Erythrocyte-binding therapeutics
#1899Pharmaceuticals in joint-linker configurations for treating pathological blood clots
#1900Monovalent blood brain barrier shuttle modules
#1901Targeted coagulation factors and method of using the same
#1902Chimeric clotting factors
#1903ADENOVIRAL TARGETING, COMPOSITIONS AND METHODS THEREFOR
#1904Interleukin 15 as selectable marker for gene transfer in lymphocytes
#1905Oncolytic HSV vector
#1906Fusion proteins for use as immunogenic enhancers for inducing antigen-specific T cell responses
#1907T-cell redirecting bispecific antibodies for treatment of disease
#1908Tumor targeted TNF-related apoptosis inducing ligand fusion polypeptide, methods and uses therefor
#1909Targeting of chondroitin sulfate glycans
#1910TARGETED THERAPEUTICS
#1911Chemokine-immunoglobulin fusion polypeptides, compositions, method of making and use thereof
#1912ENOLASE 1 (ENO1) COMPOSITIONS AND USES THEREOF
#1913Expression of chimeric polypeptide with variable lymphocyte receptors on immune cells and uses for treating cancer
#1914Lysosomal Targeting Peptides and Uses Thereof
#1915Therapeutic biologic for treatment of hepatocellular carcinoma
#1916Adeno-associated virus virions with variant capsid and methods of use thereof
#1917Adeno-associated virus virions with variant capsid and methods of use thereof
#1918IL-15 variants and uses thereof
#1919Removal of target cells by circulating virus-specific cytotoxic T-cells using MHC class I comprising complexes
#1920Methods for protein modification in pharmaceutical applications
#1921Modified microbial toxin receptor for delivering agents into cells
#1922Methods for reducing immune responses
#1923Regulation of specific spinal neurons regulating pain transmission via chimeric toxins
#1924ANTIBODY VACCINE CONJUGATES AND USES THEREFOR
#1925Lym-1 and Lym-2 targeted CAR cell immunotherapy
#1926Compositions for inducing antigen-specific tolerance
#1927Methods for induction of antigen-specific immune tolerance
#1928Compositions for generating immune tolerance by targeting erythrocytes
#1929Anti-TOSO chimeric antigen receptor and its use
#1930METHOD OF INHIBITING METASTASIS OF CANCER CELLS AND MODULATING AUTOIMMUNE DISEASES USING GAL-3BP-Fc FUSION PROTEIN
#1931OLIGOMERIZATION DOMAIN OF P53 TO BYPASS THE DOMINANT-NEGATIVE EFFECT OF MUTANT
#1932MHC CLASS I EPITOPE DELIVERING POLYPEPTIDES AND CELL-TARGETED MOLECULES FOR DIRECT CELL KILLING AND IMMUNE STIMULATION VIA MHC CLASS I PRESENTATION AND METHODS REGARDING THE SAME
#1933Factor IX polypeptides and methods of use thereof
#1934Costimulatory chimeric antigen receptor T cells targeting IL13Rα2
#1935Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)
#1936Molecular constructs for treating central nervous system diseases
#1937Molecular constructs for treating infectious diseases
#1938Compositions and methods for treatment of hematological malignancies
#1939Methods and compositions for protection against lentiviral infections
#1940DE-IMMUNIZED SHIGA TOXIN A SUBUNIT EFFECTOR POLYPEPTIDES FOR APPLICATIONS IN MAMMALS
#1941Molecular constructs with targeting and effector moieties for treating infectious diseases
#1942Molecular constructs with targeting and effector moieties comprising an SCFV specific for ectodomain of transferrin-1 receptor and fingolimod
#1943Peptide core-based multi-arm linkers for treating infectious diseases
#1944Peptide core-based multi-arm linkers for treating central nervous system diseases
#1945Peptide core-based multi-arm linkers and their applications
#1946Pseudotyped lentiviral vectors
#1947Vaccines for treatment and prevention of cancer
#1948IL-15 and IL-15R\alpha sushi domain based immunocytokines
#1949R-SPONDIN ANTAGONISTS AND METHODS OF TREATING CANCER ASSOCIATED WITH ABERRANT ACTIVATION OF WNT SIGNALING
#1950Bi-specific T-cell engager specific for BCMA
#1951Thymic stromal lymphopoietin receptor-specific chimeric antigen receptors and methods using same
#1952EGFR-based inhibitor peptides for combinatorial inactivation of ERBB1, ERBB2, and ERBB3
#1953CRP capture/detection of gram positive bacteria
#1954Compositions and methods for delivering inhibitory oligonucleotides
#1955Receptor tyrosine kinase-like orphan receptor 1 (ROR1) single chain Fv antibody fragment conjugates and methods of use thereof
#19565T4-TARGETED IMMUNOFUSION MOLECULE AND METHODS
#1957Chimeric antigen receptors targeting B-cell maturation antigen
#1958Composition and method for therapeutic agent delivery during pregnancy
#1959EPHA3 And multi-valent targeting of tumors
#1960DENDRITIC CELL ASGPR TARGETING IMMUNOTHERAPEUTICS FOR MULTIPLE SCLEROSIS
#1961Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
#1962Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
#1963ALK ANTIBODIES, CONJUGATES, AND CHIMERIC ANTIGEN RECEPTORS, AND THEIR USE
#1964Method for suppressing spasmodic torticollis
#1965Targeting tissue factor to activated platelets
#1966Binding-triggered transcriptional switches and methods of use thereof
#1967Immunoconjugates
#1968Factor IX polypeptides and methods of use thereof
#1969Targeted Delivery of Factor VIII Proteins to Platelets
#1970Oncolytic HSV vector
#1971Factor IX polypeptides and methods of use thereof
#1972IMMUNOGLOBULIN FUSION PROTEINS AND COMPOSITIONS THEREOF
#1973Anti-CTLA4 antibody-TGF-βRII targeted/immunomodulatory fusion proteins
#1974Vaults engineered for hydrophobic drug delivery
#1975Compositions and methods comprising aspartyl-tRNA synthetases having non-canonical biological activities
#1976Interleukin-2 fusion proteins and uses thereof
#1977Fusion proteins for use as immunogenic enhancers for inducing antigen-specific T cell responses
#1978MULTIPLE TARGET T CELL RECEPTOR
#1979AGENTS AND METHODS BASED ON THE USE OF THE EDA DOMAIN OF FIBRONECTIN
#1980Pseudomonas exotoxin a with less immunogenic T cell and/or B cell epitopes
#1981Molecular constructs with targeting and effector moieties
#1982Peptide core-based multi-arm linkers
#1983Human monoclonal antibodies specific for glypican-3 and use thereof
#1984Compositions and methods for treatment of cancer
#1985Molecular constructs for treating tumors
#1986Tumor necrosis factor (TNF) family ligand trimer-containing antigen-binding molecules
#1987Anti CD30 chimeric antigen receptor and its use
#1988Fusion protein comprising albumin and retinol-binding protein
#1989Compositions and methods for treatment of cancer
#1990Chimeric antigen receptor and methods of use thereof
#1991Methods of treating cancer by administering a soluble receptor comprising a human Fc domain and the Fri domain from human frizzled receptor
#1992Compositions for and methods of treating and preventing targeting tumor associated carbohydrate antigens
#1993Class of therapeutic protein based molecules
#1994Adeno-associated virus virions with variant capsid and methods of use thereof
#1995GLA-DOMAINLESS FACTOR X
#1996CELL-TARGETED MOLECULES COMPRISING AMINO-TERMINUS PROXIMAL OR AMINO-TERMINAL SHIGA TOXIN A SUBUNIT EFFECTOR REGIONS
#1997SIRP-α immunoglobulin fusion proteins
#1998T-cell redirecting bispecific antibodies for treatment of disease
#1999Peptides having specificity for the lungs
#2000Method of treating cancer with an EGFR targeted immunomodulatory fusion protein
#2001Factor IX polypeptides and methods of use thereof
#2002Coiled coil immunoglobulin fusion proteins and compositions thereof
#2003Compositions and methods for treatment of cancer
#2004NOGO Receptor Antagonists
#2005Targeting of human interferon antagonists
#2006Methods and compositions for adoptive cell therapy
#2007DESIGN AND DEVELOPMENT OF MASKED THERAPEUTIC ANTIBODIES TO LIMIT OFF-TARGET EFFECTS: APPLICATION TO ANTI-EGFR ANTIBODIES
#2008Targeted therapeutic proteins
#2009Helix-grafted proteins as inhibitors of disease-relevant protein-protein interactions
#2010Methods and compositions for treating cancer
#2011Botulinum neurotoxins with modified light chain specificity and methods for producing same
#2012ENGINEERED POLYPEPTIDES HAVING ENHANCED DURATION OF ACTION
#2013Interferon lambda-antibody complexes
#2014Methods and compositions for reducing immunosupression by tumor cells
#2015Therapeutic strategies to treat CNS pathology in mucopolysaccharidoses
#2016Composition comprised of antigen linked to a TNF superfamily ligand
#2017Interferon alpha 2B variants
#2018Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein
#2019Anti-GPIIB/IIIA antibodies or uses thereof
#2020Chemokine-immunoglobulin fusion polypeptides, compositions, method of making and use thereof
#2021Methods and compositions for treatment of Pompe disease
#2022Re-directed immunotherapy
#2023Ribotoxin molecules derived from sarcin and other related fungal ribotoxins
#2024Treatment for BK polyomavirus infection
#2025TARGETED MODULATION OF MACROPHAGES
#2026Antimicrobial Enzyme Fusions Reduce Resistance and Kill Intracellular Staphylococcus aureus
#2027Anti-CD19 scFv (FMC63) polypeptide
#2028Treatment of cancer using a CD33 chimeric antigen receptor
#2029Dps fusion proteins for use in vaccines and diagnostics
#2030METHODS AND COMPOSITIONS FOR TREATMENT OF FORBES-CORI DISEASE
#2031Removal of Cancer Cells by Circulating Virus-Specific Cytotoxic T-Cells Using Cancer Cell Targeted MHC Class 1 Compromising Multi-Function Proteins
#2032HUMAN PROTEIN SCAFFOLD WITH CONTROLLED SERUM PHARMACOKINETICS
#2033Chimeric leptin polypeptide and method of using the same
#2034CS1-specific chimeric antigen receptor engineered immune effector cells
#2035Herpes simplex virus (HSV) with modified tropism, uses and process of preparation thereof
#2036Treatment of cancer using a CD123 chimeric antigen receptor
#2037ANTI-CD19 COMPOSITIONS AND METHODS FOR TREATING CANCER
#2038Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics
#2039Targeting trastuzumab-resistant HER2+ breast cancer with a HER3-targeting nanoparticle
#2040Costimulation of chimeric antigen receptors by MyD88 and CD40 polypeptides
#2041Methods and compositions of treating autoimmune diseases
#2042MODIFIED MICROBIAL TOXIN RECEPTOR FOR DELIVERING AGENTS INTO CELLS
#2043Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
#2044Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12
#2045Devices, systems and methods for optogenetic modulation of action potentials in target cells
#2046STABILIZED SINGLE HUMAN CD4 DOMAINS AND FUSION PROTEINS
#2047IMMUNOGENIC COMPOSITION COMPRISING ALPHA-HEMOLYSIN OLIGOPEPTIDES
#2048Modified T lymphocytes comprising an inducible caspase and methods of apoptosis
#2049MOLECULAR CONJUGATES COMPRISING HUMAN MONOCLONAL ANTIBODIES TO DENDRITIC CELLS
#2050Methods of treating damaged cartilage tissue using growth factors fused to heparin binding sequences
#2051ANTIGEN PRESENTING CELL TARGETED CANCER VACCINES
#2052CD20-binding immunotoxins for inducing cellular internalization and methods using same
#2053Peptide having 5 linked CTL epitopes
#2054METHODS AND THERAPEUTICS COMPRISING LIGAND-TARGETED ELPs
#2055Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof
#2056TETRAVALENT BISPECIFIC ANTIBODIES
#2057Effective generation of tumor-targeted T cells derived from pluripotent stem cells
#2058Fusion protein comprising targeting moiety, cleavage site, and cell membrane penetrating domain, and use thereof
#2059Vault compositions for immunization
#2060Methods and compositions for targeting adipose cells in mammals
#2061Method of introducing a toxin or dye into mammalian pluripotent cells using rBC2LCN
#2062Glucagon/GLP-1 receptor co-agonists
#2063Nucleic acid construct encoding an agonistic anti-CD40 antibody and a type I interferon
#2064Treatment of metastatic tumors
#2065Deimmunized gelonin molecules and therapies
#2066Antigen-Specific T cell redirectors
#2067METHODS FOR INCREASING RED BLOOD CELL LEVELS AND TREATING SICKLE-CELL DISEASE
#2068Fusion proteins that facilitate cancer cell destruction
#2069Disulfide-linked multivalent MHC class I comprising multi-function proteins
#2070Heterodimerized polypeptide
#2071Dual-targeted therapeutic peptide for nasopharyngeal carcinoma, nanoparticles carrying same and uses thereof
#2072Compositions and methods for immunotherapy
#2073Use of fusion protein
#2074Fusion protein comprising granzyme B and use thereof
#2075High-affinity peptide-based anticancer vaccination to overcome tumor resistance to immunostimulatory antibodies and to identify TCRs that can be used successfully in adoptive T cell therapy
#2076Amphipathic peptide
#2077Combination of lenalidomide and polypeptide construct, and uses thereof
#2078Chimeric antigen receptors
#2079Compositions and methods for the display of proteins on the surface of bacteria and their derived vesicles and uses thereof
#2080NOVEL PSEUDOTYPED LENTIVIRAL PARTICLES AND THEIR USE IN THE IN VITRO TARGETED TRANSDUCTION OF UNDIFFERENTIATED PLURIPOTENT HUMAN EMBRYONIC STEM CELLS AND INDUCED PLURIPOTENT STEM CELLS
#2081Therapy of cancer based on targeting adaptive, innate and/or regulatory component of the immune response
#2082Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl tRNA synthetases
#2083Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl tRNA synthetases
#2084ANTI-SERUM ALBUMIN BINDING VARIANTS
#2085ANTIMICROBIAL COMPOSITIONS
#2086Antibody-light fusion products for cancer therapeutics
#2087Recombinant TNF ligand family member polypeptides with antibody binding domain and uses therefor
#2088HIGH-THROUGHPUT ASSAYS FOR HIV-1 ENVELOPE MATURATION AND NOVEL PEPTIDE INHIBITORS AGAINST HIV-1
#2089Conjugated knottin mini-proteins containing non-natural amino acids
#2090COMPOSITIONS AND METHODS FOR IMPROVING PRODUCTION OF RECOMBINANT POLYPEPTIDES
#2091Microtubule-modifying compound
#2092Re-directed immunotherapy
#2093Heterodimers of IL-15 and IL-15R alpha to increase thymic output and to treat lymphopenia
#2094Compositions and methods
#2095Chimeric polypeptides and their use in bacterial decolonization
#2096Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
#2097Compositions and methods for rendering tumor cells susceptible to CD8+ T cell-mediated killing
#2098Compound comprising an autoantigenic peptide and a carrier with a MHC binding motif
#2099Adeno-associated virus virions with variant capsid and methods of use thereof
#2100Targeted TGFβ inhibitors